Systematic review of preclinical and clinical evidence of Sacha inchi Terence Yew Chin Tan, Puteri Sofia Nadira Megat Kamaruddin, Siti Hajar Muhamad Rosli, Han Yin Lim, Janice Sue Wen Chan, Wan Ahmad Syazani Mohamed, Puspawathy Krishnan, Mohd Naeem Mohd Nawi, Ida Farah Ahmad, Nur Es Naini Awalludin, Sophia Rasheeqa Ismail Discover Food, 2026 Abstract Background Sacha inchi (Plukenetia volubilis), a member of the Euphorbiaceae family, has long been valued for its nutritional and medicinal properties, including use in food and cosmetic industries as a poultice to soften, revitalize, and rejuvenate the skin. Its health benefits are attributed to its rich content of essential nutrients and phytocompounds. Objective This review systematically explores and compiles current scientific evidence on the efficacy of Sacha inchi. Methods Publications were identified and selected according to the PRISMA guidelines, with predetermined inclusion criteria. Databases searched included Web of Science, CENTRAL, LILACS, Scopus, PubMed®, and EBSCOhost. Results Thirteen articles were included, primarily using oil-based extracts or products, with treatment durations ranging from one month to 20 months in human studies and 75 min to 3.5 months in animal studies. Clinical findings support the benefits of Sacha inchi for metabolic syndrome, cognitive enhancement, dry eye syndrome, and dermatological health, while animal studies suggest potential effects in managing hypertension, hyperlmia, and offering neuroprotection. Conclusions However, there remains a lack of comprehensive evaluation of specific formulations or extracts in both clinical and preclinical settings. Further research is needed, particularly regarding safety data at higher doses and for prolonged use.
The effects of school-based hygiene intervention programme: Systematic review and meta-analysis Sophia Rasheeqa Ismail, Ranina Radzi, Puteri Sofia Nadira Megat Kamaruddin, Ezarul Faradianna Lokman, Han Yin Lim, Nusaibah Abdul Rahim, Hui Yin Yow, Daarshini Arumugam, Alex Ngu, Annie Ching Yi Low, Eng Hwa Wong, Sapna Patil, Priya Madhavan, Ruslin Bin Nordin, Esther van der Werf, Nai Ming Lai Plos One, 2024 Children are susceptible to infections due to frequent participation in school group activities and their often-suboptimal hygiene practices. Frequent infections in children affect school attendance, academic performances, and general health. The effectiveness of school-based hygiene-related intervention programmes need to be informed by updated high-quality synthesised evidence. In this systematic review, we searched PubMed and Cochrane CENTRAL for randomised and non-randomised interventional studies that evaluated school-based hygiene-related interventions. We assessed risk-of-bias (Cochrane risk-of-bias 2 tool), performed random-effect meta-analysis (RevMan 5.4) and rated certainty-of-evidence (GRADE). Thirty-nine trials (41 reports), published from 2011 to 2024 from 22 countries were included. Twenty-three studies contributed data for meta-analysis. All school-based interventions were compared with standard curriculum and demonstrated very low to low certainty-of-evidence due to study methodological limitations and imprecision. Hand-body hygiene interventions may improve knowledge, attitudes and practices (SMD 2.30, 95%CI 1.17 to 3.44, 6 studies, 7301 participants), increase handwashing practices (RR 1.75, 95%CI 1.41 to 2.17, 5 studies, 5479 participants), and reduce infection-related absenteeism (RR 0.74, 95%CI 0.66 to 0.83, 5 studies, 1017852 observations). Genital hygiene interventions may improve attitude (SMD 6.53, 95%CI 2.40 to 10.66, 2 studies, 2644 participants) and practices (RR 2.44, 95%CI 1.28 to 4.68, 1 study, 1201 participants). However, intervention effects on oral hygiene appeared mixed, with worsening of the oral hygiene score (SMD 3.12, 95%CI 1.87 to 4.37, 2 studies, 652 participants) but improved dental hygiene (SMD -0.33, 95%CI -0.53 to -0.13, 3 studies, 4824 participants) and dental caries scores (SMD -0.34, 95%CI -0.52 to -0.16, 4 studies, 2352 participants). Limited evidence suggests that interventions targeting hand-body and genital hygiene practices may improve knowledge, practices, and infection-related absenteeism. However, the effects on oral hygiene intervention appeared mixed. Future research should strengthen randomisation and intervention documentation, and evaluate hygiene-related behaviour, academic performances and health outcomes.
Risk Factors of Secondary Cardiovascular Events in a Multi-Ethnic Asian Population with Acute Myocardial Infarction: A Retrospective Cohort Study from Malaysia Sophia Rasheeqa Ismail, Mohd Shawal Faizal Mohammad, Adam S. Butterworth, Rajiv Chowdhury, John Danesh, Emanuele Di Angelantonio, Simon J. Griffin, Lisa Pennells, Angela M. Wood, Mohd Fairulnizal Md Noh, Shamsul Azhar Shah Journal of Cardiovascular Development and Disease, 2023 This retrospective cohort study investigated the incidence and risk factors of major adverse cardiovascular events (MACE) after 1 year of first-documented myocardial infarctions (MIs) in a multi-ethnic Asian population. Secondary MACE were observed in 231 (14.3%) individuals, including 92 (5.7%) cardiovascular-related deaths. Both histories of hypertension and diabetes were associated with secondary MACE after adjustment for age, sex, and ethnicity (HR 1.60 [95%CI 1.22–2.12] and 1.46 [95%CI 1.09–1.97], respectively). With further adjustments for traditional risk factors, individuals with conduction disturbances demonstrated higher risks of MACE: new left-bundle branch block (HR 2.86 [95%CI 1.15–6.55]), right-bundle branch block (HR 2.09 [95%CI 1.02–4.29]), and second-degree heart block (HR 2.45 [95%CI 0.59–10.16]). These associations were broadly similar across different age, sex, and ethnicity groups, although somewhat greater for history of hypertension and BMI among women versus men, for HbA1c control in individuals aged >50 years, and for LVEF ≤ 40% in those with Indian versus Chinese or Bumiputera ethnicities. Several traditional and cardiac risk factors are associated with a higher risk of secondary major adverse cardiovascular events. In addition to hypertension and diabetes, the identification of conduction disturbances in individuals with first-onset MI may be useful for the risk stratification of high-risk individuals.
Systematic review and meta-analysis of prognostic models in Southeast Asian populations with acute myocardial infarction Sophia Rasheeqa Ismail, Muhamad Khairul Nazrin Khalil, Mohd Shawal Faizal Mohamad, Shamsul Azhar Shah Frontiers in Cardiovascular Medicine, 2022 BackgroundThe cultural and genetic diversity of the Southeast Asian population has contributed to distinct cardiovascular disease risks, incidence, and prognosis compared to the Western population, thereby raising concerns about the accuracy of predicted risks of existing prognostic models.ObjectivesWe aimed to evaluate the predictive performances of validated, recalibrated, and developed prognostic risk prediction tools used in the Southeast Asian population with acute myocardial infarction (AMI) events for secondary eventsMethodsWe searched MEDLINE and Cochrane Central databases until March 2022. We included prospective and retrospective cohort studies that exclusively evaluated populations in the Southeast Asian region with a confirmed diagnosis of an AMI event and evaluated for risk of secondary events such as mortality, recurrent AMI, and heart failure admission. The CHARMS and PRISMA checklists and PROBAST for risk of bias assessment were used in this review.ResultsWe included 7 studies with 11 external validations, 3 recalibrations, and 3 new models from 4 countries. Both short- and long-term outcomes were assessed. Overall, we observed that the external validation studies provided a good predictive accuracy of the models in the respective populations. The pooled estimate of the C-statistic in the Southeast Asian population for GRACE risk score is 0.83 (95%CI 0.72–0.90, n = 6 validations) and for the TIMI risk score is 0.80 (95%CI: 0.772–0.83, n = 5 validations). Recalibrated and new models demonstrated marginal improvements in discriminative values. However, the method of predictive accuracy measurement in most studies was insufficient thereby contributing to the mixed accuracy effect. The evidence synthesis was limited due to the relatively low quality and heterogeneity of the available studies.ConclusionBoth TIMI and GRACE risk scores demonstrated good predictive accuracies in the population. However, with the limited strength of evidence, these results should be interpreted with caution. Future higher-quality studies spanning various parts of the Asian region will help to understand the prognostic utility of these models better.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?%20RecordID=228486.
FACTORS AND CHARACTERISTICS ASSOCIATED WITH ASYMPTOMATIC COVID-19 INFECTION IN A DISTRICT SETTING IN MALAYSIA Asraf Qamruddin, Sophia Rasheeqa Ismail, Awanis Sharif, Reza Murad Qamruddin Malaysian Journal of Public Health Medicine, 2022 We aimed to determine the prevalence, characteristics, and risk factors associated with asymptomatic COVID-19 cases in a district setting in Malaysia. We included all confirmed COVID-19 cases within the district from inception to March 2021. Out of 3,051 confirmed COVID-19 cases, 1,862 (61.0%) were asymptomatic. Asymptomatic cases were mostly men, younger, non-Malaysians and had fewer comorbidities. The highest prevalence of asymptomatic cases was from prisons and factories. Male gender (adjusted OR 2.02; 95%CI 1.69 – 2.43), non-Malaysians (adjusted OR 20.00; 95%CI 14.75 – 27.64), current smoking status (adjusted OR 12.06; 95%CI 6.74 – 23.94), prisoners (adjusted OR 19.02; 95%CI 12.30 – 30.57), and higher CT values were significantly associated with asymptomatic COVID-19 infection. To ensure more targeted public health prevention and infection containment strategies, authorities and employers should be more aware of their local population's heterogeneity, risk factors, and unique conditions.
Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study Rajiv Chowdhury, Mohd Fairulnizal Md Noh, Sophia Rasheeqa Ismail, Kim Robin van Daalen, Puteri Sofia Nadira Megat Kamaruddin, Siti Hafizah Zulkiply, Nur Hayati Azizul, Norhayati Mustafa Khalid, Azizan Ali, Izyan Mohd Idris, Yong Shih Mei, Shazana Rifham Abdullah, Norfashihah Faridus, Nur Azirah Md Yusof, Nur Najwa Farahin M Yusoff, Rahman Jamal, Aizai Azan Abdul Rahim, Abdul Kahar Abdul Ghapar, Ammu Kutty Radhakrishnan, Alan Yean Yip Fong, Omar Ismail, Saravanan Krishinan, Chuey Yan Lee, Liew Houng Bang, Eashwary Mageswaren, Kauthaman Mahendran, Nor Hanim Mohd Amin, Gunavathy Muthusamy, Aaron Ong Hean Jin, Ahmad Wazi Ramli, Noel Thomas Ross, Anwar Irawan Ruhani, Mansor Yahya, Yusniza Yusoff, Siti Khairani Zainal Abidin, Laryssa Amado, Thomas Bolton, Sophie Weston, Jason Crawte, Niko Ovenden, Ank Michielsen, Md Mostafa Monower, Wan Rozita Wan Mahiyuddin, Angela Wood, Emanuele Di Angelantonio, Nur Suffia Sulaiman, John Danesh, Adam S Butterworth Jmir Research Protocols, 2022 Background Although the burden of premature myocardial infarction (MI) is high in Malaysia, direct evidence on the determinants of MI in this multi-ethnic population remains sparse. Objective The Malaysian Acute Vascular Events Risk (MAVERIK) study is a retrospective case-control study established to investigate the genomic, lipid-related, and other determinants of acute MI in Malaysia. In this paper, we report the study protocol and early results. Methods By June 2019, we had enrolled approximately 2500 patients with their first MI and 2500 controls without cardiovascular disease, who were frequency-matched by age, sex, and ethnicity, from 17 hospitals in Malaysia. For each participant, serum and whole blood have been collected and stored. Clinical, demographic, and behavioral information has been obtained using a 200-item questionnaire. Results Tobacco consumption, a history of diabetes, hypertension, markers of visceral adiposity, indicators of lower socioeconomic status, and a family history of coronary disease were more prevalent in cases than in controls. Adjusted (age and sex) logistic regression models for traditional risk factors indicated that current smoking (odds ratio [OR] 4.11, 95% CI 3.56-4.75; P<.001), previous smoking (OR 1.34, 95% CI 1.12-1.60; P=.001), a history of high blood pressure (OR 2.13, 95% CI 1.86-2.44; P<.001), a history of diabetes mellitus (OR 2.72, 95% CI 2.34-3.17; P<.001), a family history of coronary heart disease (OR 1.28, 95% CI 1.07-1.55; P=.009), and obesity (BMI >30 kg/m2; OR 1.19, 95% CI 1.05-1.34; P=.009) were associated with MI in age- and sex-adjusted models. Conclusions The MAVERIK study can serve as a useful platform to investigate genetic and other risk factors for MI in an understudied Southeast Asian population. It should help to hasten the discovery of disease-causing pathways and inform regionally appropriate strategies that optimize public health action. International Registered Report Identifier (IRRID) RR1-10.2196/31885
Evidence of disease severity, cognitive and physical outcomes of dance interventions for persons with Parkinson’s Disease: a systematic review and meta-analysis Sophia Rasheeqa Ismail, Shaun Wen Huey Lee, Dafna Merom, Puteri Sofia Nadira Megat Kamaruddin, Min San Chong, Terence Ong, Nai Ming Lai BMC Geriatrics, 2021 Background Patients with Parkinson’s Disease (PD) usually experience worsening of both motor and non-motor symptoms. Dancing has been postulated to help patients with Parkinson’s via several mechanisms that lead to improved physical, cognitive and social functions. Methods This systematic review was conducted following Cochrane methodology and reported following the PRISMA guideline. Four databases (up to June 2021) were searched for RCTs comparing dance to standard or other physical therapy for improvements in disease severity, quality of life, cognitive and physical outcomes as well as adverse events in patients with PD. We synthesised data using RevMan and included certainty-of-evidence rating (GRADE) for major outcomes. Results A total of 20 RCTs (N = 723) articles that evaluated Tango, Ballroom, Irish, Waltz-Foxtrot, Folk, Turo, mixed dances and a PD-tailored dance were included. Dancers (versus non-dancers) had better motor experience (MDS-UPDRS 3) (MD -6.01, 95 % CI -9.97 to -3.84; n = 148; 5 RCTs) and improved balance (MiniBest Test) (MD 4.47, 95 % CI 2.29 to 6.66; n = 95; 3 RCTs), with no consistent differences on gait, agility and cognitive outcomes. Small samples and methodological limitations resulted in low-certainty-evidence across outcomes. Conclusions Apart from a suggestion that dance intervention modestly reduced motor disease severity and improved certain aspects of balance, there is insufficient evidence on all other outcomes, such as agility and motor function, cognitive, mood and social outcomes, quality of life as well as adverse events including the risk of fall. As evidence is insufficient to inform practice, evidence of benefits on motor disease severity and balance needs to be considered in the context of user-perception of benefit versus harm and acceptability in the development of practice guideline recommendations.
Effects of palm oil consumption on biomarkers of glucose metabolism: A systematic review Siti Hafizah Zulkiply, Vimala Balasubramaniam, Nur Ain Abu Bakar, Aswir Abd Rashed, Sophia Rasheeqa Ismail Plos One, 2019 Introduction Vegetable oil is an important source of fatty acids, and as palm oil being the highest consumed vegetable oil in many countries, its high saturated fatty acid content has led many concerns on cardiometabolic health. Dietary fatty acids has also been linked to affect glucose metabolism and insulin sensitivity. This systematic review is aimed at critically evaluating the available evidence on the association of palm oil with the biomarkers of glucose metabolism as compared to other vegetable oils. Methods We systemically searched PubMed, CENTRAL and Scopus up to June 2018. We searched for published interventional studies on biomarkers of glucose metabolism (defined as fasting glucose, fasting insulin, HOMA, 2-hour post prandial glucose and HbA1C) that compared palm oil- or palm olein-rich diets with other edible vegetable oils (such as olive oil, canola oil and soybean oil). Two reviewers independently extracted data and assessed study risks of bias. Mean differences of outcomes were pooled for the meta-analysis. Results We identified 1921 potentially eligible articles with only eight included studies. Seven randomised cross-over trials and one parallel trial were included. Study population were among young to middle-aged, healthy, non-diabetic, and normal weight participants. Intervention duration ranged from three to seven weeks, and fat substitution ranged from 15% to 20% energy. There were insignificant differences in fasting glucose when compared to partially hydrogenated soybean oil [-0.15mmol/L (-0.46,0.16) P = 0.33, I2 = 48%], soybean oil [0.05mmol/L (-0.09,0.18) P = 0.49, I2 = 0%] and olive oil [0.04mmol/L (-0.09,0.17) P = 0.76, I2 = 0%]. Insignificant effects were also seen on fasting insulin when compared to partially hydrogenated soybean oil [1.72pmol/L (-11.39,14.84) P = 0.80, I2 = 12%] and olive oil diet [-0.14pmol/L (-4.87,4.59) P = 0.95, I2 = 0%]. Conclusion Current evidence on the effects of palm oil consumption on biomarkers of glucose metabolism is poor and limited to only healthy participants. We conclude that little or no additional benefit will be obtained by replacing palm oil with other oils rich in mono or polyunsaturated fatty acids for changes in glucose metabolism.
Systematic review of palm oil consumption and the risk of cardiovascular disease Sophia Rasheeqa Ismail, Siti Khuzaimah Maarof, Syazwani Siedar Ali, Azizan Ali Plos One, 2018 Background The high amount of saturated fatty acids (SFA) coupled with the rising availability and consumption of palm oil have lead to the assumption that palm oil contributes to the increased prevalence of cardiovascular diseases worldwide. We aimed at systematically synthesising the association of palm oil consumption with cardiovascular disease risk and cardiovascular disease-specific mortality. Methods We systematically searched Central, Medline and Embase databases up to June 2017 without restriction on setting or language. We performed separate searches based on the outcomes: coronary heart disease and stroke, using keywords related to these outcomes and palm oil. We searched for published interventional and observational studies in adults (Age: >18 years old). Two investigators extracted data and a consensus was reached with involvement of a third. Only narrative synthesis was performed for all of the studies, as the data could not be pooled. Results Our search retrieved 2,738 citations for stroke with one included study and 1,777 citations for coronary heart disease (CHD) with four included studies. Palmitic acid was reported to be associated with risk of myocardial infarction (MI) (OR 2.76; 95%CI = 1.39–5.47). Total SFA intake was reported to be not significant for risk of MI. Varying intake of fried foods, highest contributor to total SFA with 36% of households using palm oil for frying, showed no significant associations to risk of MI. Odds of developing first non-fatal acute MI was higher in palm oil compared to soybean oil with 5% trans-fat (OR = 1.33; 95%CI = 1.09–1.62) than palm oil compared to soybean oil with 22% trans-fat (OR = 1.16; 95%CI = 0.86–1.56). Nevertheless, these risk estimates were non-significant and imprecise. The trend amongst those taking staple pattern diet (characterised by higher palm oil, red meat and added sugar consumption) was inconsistent across the factor score quintiles. During the years of 1980 and 1997, for every additional kilogram of palm oil consumed per-capita annually, CHD mortality risk was 68 deaths per 100,000 (95% CI = 21–115) in developing countries and 17 deaths per 100,000 (95%CI = 5.3–29) in high-income countries, whereas stroke was associated with 19 deaths per 100,000 (95%CI = -12–49) and 5.1 deaths per 100,000 (95% CI: -1.2–11) respectively. The evidence for the outcomes of this review were all graded as very low. The findings of this review should be interpreted with some caution, owing to the lack of a pooled effect estimate of the association, significant bias in selection criteria and confounding factors, inclusion of other food items together with palm oil, and the possible out-dated trend in the ecological study. Conclusion In view of the abundance of palm oil in the market, quantifying its true association with CVD outcomes is challenging. The present review could not establish strong evidence for or against palm oil consumption relating to cardiovascular disease risk and cardiovascular disease-specific mortality. Further studies are needed to establish the association of palm oil with CVD. A healthy overall diet should still be prioritised for good cardiometabolic health.
RECENT SCHOLAR PUBLICATIONS
Systematic review of preclinical and clinical evidence of Sacha inchi TYC Tan, PSNM Kamaruddin, SHM Rosli, HY Lim, JSW Chan, ... Discover Food , 2026 2026
Cocoa: Production, Composition and Health Effects TYC Tan, XY Lim, SR Ismail, SHM Rosli, JSW Chan, K Jetly, FH Mohkiar, ... Elsevier , 2026 2026
The effects of school-based hygiene intervention programme: Systematic review and meta-analysis SR Ismail, R Radzi, PSN Megat Kamaruddin, EF Lokman, HY Lim, ... Plos one 19 (10), e0308390 , 2024 2024 Citations: 31
Risk factors of secondary cardiovascular events in a multi-ethnic Asian population with acute myocardial infarction SR Ismail, MSF Mohammad, AS Butterworth, R Chowdhury, J Danesh, ... International Journal of Cardiology 393, 131450 , 2023 2023
Risk factors of secondary cardiovascular events in a multi-ethnic Asian population with acute myocardial infarction: A retrospective cohort study from Malaysia SR Ismail, MSF Mohammad, AS Butterworth, R Chowdhury, J Danesh, ... Journal of Cardiovascular Development and Disease 10 (6), 250 , 2023 2023 Citations: 7
Cigarette smoking and first onset of myocardial infarction in Malaysia NAZ Abidin, SR Abdullah, SR Ismail, MFM Noh International Journal of Cardiology 369, 48 , 2022 2022
Analysis of heavy metal levels in nails of myocardial infarction patients using inductively coupled plasma-mass spectrometry: The MAVERIK case-control study protocol RJM Salim, MFM Noh, ZF Annual, N Faridus, MF Zulkifle, NS Sulaiman, ... International Journal of Cardiology 369, 44 , 2022 2022
Elevated lipoprotein (a) another significant predictor of first-onset myocardial infarction among Malaysian adults YZ Tan, SR Abdullah, SR Ismail, MFM Noh International Journal of Cardiology 369, 45-46 , 2022 2022
Association between anthropometric factors and first-onset acute myocardial infarction: The MAVERIK case-control study FH Mohkiar, SR Abdullah, SR Ismail, MFM Noh International Journal of Cardiology 369, 48 , 2022 2022
Systematic review and meta-analysis of prognostic models in Southeast Asian populations with acute myocardial infarction SR Ismail, MKN Khalil, MSF Mohamad, S Azhar Shah Frontiers in Cardiovascular Medicine 9, 921044 , 2022 2022 Citations: 9
FACTORS ASSOCIATED WITH ASYMPTOMATIC COVID-19 INFECTION IN A DISTRICT SETTING IN MALAYSIA A Qamruddin, SR Ismail, A Sharif, RM Qamruddin Malaysian Journal of Public Health Medicine 22 (1), 28-37 , 2022 2022
Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study R Chowdhury, MFM Noh, SR Ismail, KR van Daalen, PSNM Kamaruddin, ... JMIR Research Protocols 11 (2), e31885 , 2022 2022 Citations: 1
Evidence of disease severity, cognitive and physical outcomes of dance interventions for persons with Parkinson’s Disease: a systematic review and meta-analysis SR Ismail, SWH Lee, D Merom, PSN Megat Kamaruddin, MS Chong, ... BMC geriatrics 21 (1), 503 , 2021 2021 Citations: 53
Effects of palm oil consumption on biomarkers of glucose metabolism: A systematic review SH Zulkiply, V Balasubramaniam, NA Abu Bakar, A Abd Rashed, ... PloS one 14 (8), e0220877 , 2019 2019 Citations: 32
Systematic review of palm oil consumption and the risk of cardiovascular disease SR Ismail, SK Maarof, S Siedar Ali, A Ali PLoS One 13 (2), e0193533 , 2018 2018 Citations: 157
Therapy-related strategies to improve adherence to cardiovascular medications SR Ismail, S Tsoli, R Chowdhury Medicographia 39, 280-288 , 2017 2017 Citations: 4
Therapy-related strategies to improve adherence to diabetic medications SR Ismail, S Tsoli, R Chowdhury Medicographia 39 (4), 289-297 , 2017 2017
Reclamation from palm oil mill effluent using an integrated zero discharge membrane-based process AL Ahmad, I Idris, CY Chan, S Ismail Polish Journal of Chemical Technology 17 (4) , 2015 2015 Citations: 23
Gerwin, BI 142, 55 T Abe, Y Akasaki, T Akimoto, M Akiyama, A Ali, MC Alonso, A Asai, ... Cancer Letters 142 (221), 222 , 1999 1999
Clarification of Microbial Extracts by Microfiltration with Limiting Permeate Slux Operation BS Baharin, S Ismail, AB Ali Secretariat 9th National Biotechnology Seminar c/o Centre for Gene Analysis … , 1997 1997
MOST CITED SCHOLAR PUBLICATIONS
Systematic review of palm oil consumption and the risk of cardiovascular disease SR Ismail, SK Maarof, S Siedar Ali, A Ali PLoS One 13 (2), e0193533 , 2018 2018 Citations: 157
Evidence of disease severity, cognitive and physical outcomes of dance interventions for persons with Parkinson’s Disease: a systematic review and meta-analysis SR Ismail, SWH Lee, D Merom, PSN Megat Kamaruddin, MS Chong, ... BMC geriatrics 21 (1), 503 , 2021 2021 Citations: 53
Effects of palm oil consumption on biomarkers of glucose metabolism: A systematic review SH Zulkiply, V Balasubramaniam, NA Abu Bakar, A Abd Rashed, ... PloS one 14 (8), e0220877 , 2019 2019 Citations: 32
The effects of school-based hygiene intervention programme: Systematic review and meta-analysis SR Ismail, R Radzi, PSN Megat Kamaruddin, EF Lokman, HY Lim, ... Plos one 19 (10), e0308390 , 2024 2024 Citations: 31
Reclamation from palm oil mill effluent using an integrated zero discharge membrane-based process AL Ahmad, I Idris, CY Chan, S Ismail Polish Journal of Chemical Technology 17 (4) , 2015 2015 Citations: 23
Systematic review and meta-analysis of prognostic models in Southeast Asian populations with acute myocardial infarction SR Ismail, MKN Khalil, MSF Mohamad, S Azhar Shah Frontiers in Cardiovascular Medicine 9, 921044 , 2022 2022 Citations: 9
Risk factors of secondary cardiovascular events in a multi-ethnic Asian population with acute myocardial infarction: A retrospective cohort study from Malaysia SR Ismail, MSF Mohammad, AS Butterworth, R Chowdhury, J Danesh, ... Journal of Cardiovascular Development and Disease 10 (6), 250 , 2023 2023 Citations: 7
Therapy-related strategies to improve adherence to cardiovascular medications SR Ismail, S Tsoli, R Chowdhury Medicographia 39, 280-288 , 2017 2017 Citations: 4
Investigating Genetic and Other Determinants of First-Onset Myocardial Infarction in Malaysia: Protocol for the Malaysian Acute Vascular Events Risk Study R Chowdhury, MFM Noh, SR Ismail, KR van Daalen, PSNM Kamaruddin, ... JMIR Research Protocols 11 (2), e31885 , 2022 2022 Citations: 1
Systematic review of preclinical and clinical evidence of Sacha inchi TYC Tan, PSNM Kamaruddin, SHM Rosli, HY Lim, JSW Chan, ... Discover Food , 2026 2026
Cocoa: Production, Composition and Health Effects TYC Tan, XY Lim, SR Ismail, SHM Rosli, JSW Chan, K Jetly, FH Mohkiar, ... Elsevier , 2026 2026
Risk factors of secondary cardiovascular events in a multi-ethnic Asian population with acute myocardial infarction SR Ismail, MSF Mohammad, AS Butterworth, R Chowdhury, J Danesh, ... International Journal of Cardiology 393, 131450 , 2023 2023
Cigarette smoking and first onset of myocardial infarction in Malaysia NAZ Abidin, SR Abdullah, SR Ismail, MFM Noh International Journal of Cardiology 369, 48 , 2022 2022
Analysis of heavy metal levels in nails of myocardial infarction patients using inductively coupled plasma-mass spectrometry: The MAVERIK case-control study protocol RJM Salim, MFM Noh, ZF Annual, N Faridus, MF Zulkifle, NS Sulaiman, ... International Journal of Cardiology 369, 44 , 2022 2022
Elevated lipoprotein (a) another significant predictor of first-onset myocardial infarction among Malaysian adults YZ Tan, SR Abdullah, SR Ismail, MFM Noh International Journal of Cardiology 369, 45-46 , 2022 2022
Association between anthropometric factors and first-onset acute myocardial infarction: The MAVERIK case-control study FH Mohkiar, SR Abdullah, SR Ismail, MFM Noh International Journal of Cardiology 369, 48 , 2022 2022
FACTORS ASSOCIATED WITH ASYMPTOMATIC COVID-19 INFECTION IN A DISTRICT SETTING IN MALAYSIA A Qamruddin, SR Ismail, A Sharif, RM Qamruddin Malaysian Journal of Public Health Medicine 22 (1), 28-37 , 2022 2022
Therapy-related strategies to improve adherence to diabetic medications SR Ismail, S Tsoli, R Chowdhury Medicographia 39 (4), 289-297 , 2017 2017
Gerwin, BI 142, 55 T Abe, Y Akasaki, T Akimoto, M Akiyama, A Ali, MC Alonso, A Asai, ... Cancer Letters 142 (221), 222 , 1999 1999
Clarification of Microbial Extracts by Microfiltration with Limiting Permeate Slux Operation BS Baharin, S Ismail, AB Ali Secretariat 9th National Biotechnology Seminar c/o Centre for Gene Analysis … , 1997 1997
