Stalin Antony

Scopus Publications

Photoprotective effects of deinoxanthin against UVA-Induced oxidative damage: an integrative computational and cellular analysis
Karankumar Balamurugan, Antony Stalin, Charan Singh Pawar, N. Rajendra Prasad
Archives of Dermatological Research, 2026
Musizin from Rhamnus wightii and Its Derivatives Attenuate Non-Alcoholic Fatty Liver Disease in Palmitate Oleate–Induced HepG2 Hepatocytes
Tharsius Raja William Raja, Antony Stalin, Veeramuthu Duraipandiyan, Kedike Balakrishna, Savarimuthu Ignacimuthu, et al.
Revista Brasileira De Farmacognosia, 2026
The preference for ammonium may be attributed to a hyperpolarized membrane potential via TWIK-1 channels
Lanying Pan, Brendan Zhu, Simon L Vu, Antony Stalin, Ashley Winters, et al.
Brain Research, 2026
Editorial: Natural medicines for metabolic diseases – computational and pharmacological approaches, Volume II
Antony Stalin, Christudas Sunil, Abd El-Latif Hesham, Savarimuthu Ignacimuthu, Quan Zou, et al.
Frontiers in Pharmacology, 2026
EnDeep4mC predicts DNA N4-methylcytosine sites using a dual-adaptive feature encoding framework in deep ensembles
Shuyu Zhang, Quan Zou, Mengting Niu, Zhibin Lv, Antony Stalin, et al.
Genome Research, 2026
DNA N 4 -methylcytosine (4mC), a key epigenetic modification regulating DNA repair and replication, requires efficient computational detection methods due to experimental limitations. Although machine learning predictors have been proposed, their performance could be enhanced through systematic optimization of feature encoding schemes. Here, we propose EnDeep4mC, a dual-adaptive framework integrating species-specific modeling with ensemble deep learning architectures to systematically optimize feature encoding schemes. Evaluated across six species, EnDeep4mC demonstrates commendable prediction performance and significantly outperforms current state-of-the-art predictors. Cross-species validation confirms its robust transferability from animal to microbe groups. Evolutionary analysis further uncovers the functional differentiation of 4mC sequences in biological evolution: Prokaryotic 4mC relies on stable patterns, whereas eukaryotes achieve regulatory plasticity through dynamic sequence combinations, which provides experimental evidence for species-adaptive encoding strategies.
Editorial: Novel natural therapies for infectious diseases using computational and pharmacological approaches
Antony Stalin, Pachaiyappan Saravana Kumar, Claudio Ferrante, Abd El-Latif Hesham, Savarimuthu Ignacimuthu, et al.
Frontiers in Pharmacology, 2026
Integrating bulk and single cell sequencing data to identify prognostic biomarkers and drug candidates in HBV associated hepatocellular carcinoma
Scientific Reports, 2025
hERG Channel Blockade and Antagonistic Interactions of Three Steroidal Alkaloids from Fritillaria Species
Hui Lu, Tingting Hao, Zixuan Zhang, Chenxin Jiang, Jianwei Xu, et al.
Molecules, 2025
The bulb of Fritillaria species called “Bei Mu” is a well-known traditional Chinese medicine. We have reported some potential off-target effects of “Bei Mu” due to peimine’s blockade of hERG (human Ether-a-go-go-Related Gene) channels. This research investigated the modulatory effects of three major alkaloid analogs of “Bei Mu” and their cooperative effects on hERG channels using manual whole-cell patch-clamp techniques. Results showed that peiminine and sipeimine blocked hERG currents with IC50s of 36.8 ± 2.5 μM and 47.6 ± 9.8 μM, which were close to that of peimine (26.1 ± 3.5 μM). Peiminine-induced blockade increased with increasing depolarizing strengths, durations, and frequencies, which suggested a preferential binding to open or inactivated states. The reduced blockade by the less inactivating S631A mutation supported peiminine‘s inactivation preference. Molecular docking and dynamics simulations confirmed the hERG-blocking activities of the three alkaloids and provided further insight into potential mechanisms. We also discovered antagonistic effects of the three alkaloids at nearly all concentrations tested, which might help reduce potential cardiotoxicities. To our knowledge, this is the first study to investigate combination effects of chemicals from one herb on hERG channels. In conclusion, peiminine and sipeimine can block hERG channels in a way similar to peimine, but antagonistic effects exist among them.
In silico molecular docking analysis on acetylcholinesterase (AChE) inhibition activity on Aedes aegypti and Culex quinquefasciatus by β-isocostic acid
Alex Yagoo, M.C. John Milton, Jelin Vilvest, Antony Stalin
Journal of Asia Pacific Entomology, 2025
Green synthesis of copper hydroxide nanorods using Solanum pubescens leaf extracts: a promising approach for antimicrobial, antioxidant, and anticancer applications
C. Neela Mohan, V. Ayyadurai, Karuppiah Nagaraj, P. Vijaya Kumar, K. Raja, et al.
3 Biotech, 2025
Identifying the DNA methylation preference of transcription factors using ProtBERT and SVM
Yanchao Li, Quan Zou, Qi Dai, Antony Stalin, Ximei Luo
Plos Computational Biology, 2025
Exploration of the regulatory mechanism of norcantharidin on sine oculis homeobox homolog 4 in colon cancer using transcriptome sequencing and bioinformatic
Fanqin Zhang, Chao Wu, Jingyuan Zhang, Zhihong Huang, Antony Stalin, et al.
Journal of Traditional Chinese Medical Sciences, 2025
Activity of Essential Oils From Pentanema indicum (L.) Y. Ling and Chromolaena odorata (L.) R.M.King & H. Rob Against Three Mosquito Species
Pathalam Ganesan, Jeyaraj Selvakumaran, Savarimuthu Ignacimuthu, Badr Aldahmash, Ahmed Rady, et al.
Entomological Research, 2025
Effects of host age and size on progeny production and different foods on the adult longevity of Spalangia nigroaenea Curtis (Hymenoptera: Pteromalidae) reared on puparia of Musca domestica L. (Diptera: Muscidae)
Narayanan Velayudham, Irrusappan Hari, Antony Stalin, Mukesh Kumar Dharmalingam Jothinathan, Rajakrishnan Rajagopal, et al.
Biocontrol Science and Technology, 2025
Enhanced Bioactivity of Streptomycin Bioconjugated Metal Nanoparticles Against Streptomycin Resistant Bacillus Sp
Nishanthi Ramasami, Manikandan Dhayalan, Malathi Selvaraj, Savaas Umar Mohammed Riyaz, Palani Perumal, et al.
Indian Journal of Microbiology, 2024
Anticancer effects of rutin from Fagopyrum tataricum (tartary buckwheat) against osteosarcoma cell line
Dennis Soosai, Ravindhran Ramalingam, Elumalai Perumal, Kaviarasan Veeramani, Charles Pancras, et al.
Molecular Biology Reports, 2024
Antimycobacterial activity of plant compounds against extensively drug resistant (XDR-TB) Mycobacterium tuberculosis
Duraipandiyan Veeramuthu, Ignacimuthu Savarimuthu, Inshad Ali Khan, Hissah Abdulrahman Alodaini, Ashraf Atef Hatamleh, et al.
Journal of King Saud University Science, 2024
Exploring the antiviral inhibitory activity of Niloticin against the NS2B/NS3 protease of Dengue virus (DENV2)
Antony Stalin, Jiajia Han, Appadurai Daniel Reegan, Savarimuthu Ignacimuthu, Shuwen Liu, et al.
International Journal of Biological Macromolecules, 2024
Effectiveness of Bairui granules in the treatment of respiratory tract infections: A systematic review and meta-analysis
Keyan Chai, Haojia Wang, Yueqin Guan, Rui Shi, Antony Stalin, et al.
Medicine United States, 2024
Evaluation of mosquitocidal, histopathological and non-target effect of botanical pesticides from Stemodia viscosa and their mixtures against immature stages of Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus
Jeyaraj Selvakumaran, Kamaraj Ragavendran, Mariappan Muthukanagavel, Savarimuthu Ignacimuthu, Nayagam Vasanth, et al.
Biologia, 2024
Potential inhibition of SARS-CoV-2 infection and its mutation with the novel geldanamycin analogue: Ignaciomycin
Antony Stalin, Pachaiyappan Saravana Kumar, Balakrishnan Senthamarai Kannan, Rajamanikam Saravanan, Savarimuthu Ignacimuthu, et al.
Arabian Journal of Chemistry, 2024
Advances in functional lipid nanoparticles: from drug delivery platforms to clinical applications
Manikandan Dhayalan, Wei Wang, S. U. Mohammed Riyaz, Rakshi Anuja Dinesh, Jayashree Shanmugam, et al.
3 Biotech, 2024
Evaluating the Therapeutic Importance of Gold Nanoparticles Formed by the Biogenic Synthesis Route of Madhuca longifolia Reduction
Manikandan Dhayalan, Sheikdawood Parveen, Sathiyapriya Thirumalaisamy, Faruq Mohammad, Hamad A. Al-Lohedan, et al.
Bioresources, 2024
The anti-hepatocellular carcinoma effect of Aidi injection was related to the synergistic action of cantharidin, formononetin, and isofraxidin through BIRC5, FEN1, and EGFR
Shan Lu, Jiaqi Huang, Jingyuan Zhang, Chao Wu, Zhihong Huang, et al.
Journal of Ethnopharmacology, 2024
Corrigendum to “Integrated serum pharmacochemistry, 16S rRNA sequencing and metabolomics to reveal the material basis and mechanism of Yinzhihuang granule against non-alcoholic fatty liver disease” [J. Ethnopharmacol. 310 (2023) 116418] (Journal of Ethnopharmacology (2023) 310, (S0378874123002866), (10.1016/j.jep.2023.116418))
Yingying Tan, Zhihong Huang, Yingying Liu, Xiaojiaoyang Li, Antony Stalin, et al.
Journal of Ethnopharmacology, 2024
Editorial: Herbal medical products for metabolic diseases - new integrated pharmacological approaches
Antony Stalin, Abd El-Latif Hesham, Avdesh Mishra, Quan Zou, Savarimuthu Ignacimuthu
Frontiers in Pharmacology, 2024
Mosquitocidal efficacy of niloticin, isolated from Limonia acidissima L. (Rutaceae) against filarial vector Culex quinquefasciatus Say. (Diptera: Culicidae)
Appadurai Daniel Reegan, Antony Stalin, Munusamy Rajiv Gandhi, Santiagu Stephen Irudayaraj, Rajakrishnan Rajagopal, et al.
Toxin Reviews, 2024
Topical antifungal keratitis therapeutic potential of Clitoria ternatea Linn. flower extract: phytochemical profiling, in silico modelling, and in vitro biological activity assessment
Poomany Arul Soundara Rajan Yolin Angel, Palanisamy Jeyakumar, Arul Raj Jasmin Suriya, Aliyas Sheena, Ponmurugan Karuppiah, et al.
Frontiers in Microbiology, 2024
Investigating the Potential Mechanism of Huazhi Rougan Granules Against Alcoholic Liver Disease by Network Pharmacology and Experiment
Ying-Ying Tan, Ying-Ying Liu, Yi-Yan Zhai, Yi-Xuan Wang, Zhi-Shan Wu, et al.
World Journal of Traditional Chinese Medicine, 2024
Systematic review and meta-analysis on the efficacy and safety of Injectable Lentinan combined with chemotherapy in the treatment of gastric cancer
Yixuan Wang, Haojia Wang, Keyan Chai, Siyu Guo, Yiyan Zhai, et al.
Phytomedicine, 2024
Identification of key pharmacological components and targets for Aidi injection in the treatment of pancreatic cancer by UPLC-MS, network pharmacology, and in vivo experiments
Haojia Wang, Zhishan Wu, Xiaotian Fan, Chao Wu, Shan Lu, et al.
Chinese Medicine United Kingdom, 2023
Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking
Yingying Tan, Fanqin Zhang, Xiaotian Fan, Shan Lu, Yingying Liu, et al.
Chinese Medicine United Kingdom, 2023
Data mining combines bioinformatics discover immunoinfiltration-related gene SERPINE1 as a biomarker for diagnosis and prognosis of stomach adenocarcinoma
Yiyan Zhai, Xinkui Liu, Zhihong Huang, Jingyuan Zhang, Antony Stalin, et al.
Scientific Reports, 2023
Correction: Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking (Chinese Medicine, (2023), 18, 1, (52), 10.1186/s13020-023-00759-z)
Yingying Tan, Fanqin Zhang, Xiaotian Fan, Shan Lu, Yingying Liu, et al.
Chinese Medicine United Kingdom, 2023
Ecofriendly biofunctionalized gold nanoparticles using naturally available extract and evaluation of antioxidant, anticancer, antimicrobial and their toxicity in brine shrimp
Devan Elumalai, Maduraiveeran Hemavathi, Durai Mary, Rajan Renuka Remya, Hamid Naima, et al.
Biocatalysis and Agricultural Biotechnology, 2023
Effect of biofilm formation and cytotoxicity of biogenic silver nanoparticles (AgNPs) synthesized from a medicinal plant Sterculia foetida L.
N. Vasanth, T. Dons, L. J. Michaelraj, P. Ganesan, S. H. Salmen, et al.
Digest Journal of Nanomaterials and Biostructures, 2023
The Inhibitory Effect of Magnolol on the Human TWIK1 Channel Is Related to G229 and T225 Sites
Jintao Wang, Huan Liu, Zhuolin Sun, Xinyi Zou, Zixuan Zhang, et al.
Molecules, 2023
Elucidation of Immune Regulation Mechanism of Renshen Guben Oral Liquid by Network Pharmacology and Molecular Docking
Ying-Ying Tan, Ying-Ying Liu, Jing-Yuan Zhang, Jia-Lin Li, Pei-Zhi Ye, et al.
World Journal of Traditional Chinese Medicine, 2023
Compound Kushen Injection inhibits epithelial-mesenchymal transition of gastric carcinoma by regulating VCAM1 induced by the TNF signaling pathway
Zhihong Huang, Chao Wu, Wei Zhou, Shan Lu, Yingying Tan, et al.
Phytomedicine, 2023
Integrated network pharmacology analysis and in vitro validation revealed the underlying mechanism of Xiyanping injection in treating coronavirus disease 2019
Jialin Li, Siyu Guo, Yingying Tan, Jingyuan Zhang, Zhishan Wu, et al.
Medicine United States, 2023
Identification of an immune-related 6-lncRNA panel with a good performance for prognostic prediction in hepatocellular carcinoma by integrated bioinformatics analysis
Shan Lu, Xinkui Liu, Chao Wu, Jingyuan Zhang, Antony Stalin, et al.
Medicine United States, 2023
The Strength of hERG Inhibition by Erythromycin at Different Temperatures Might Be Due to Its Interacting Features with the Channels
Dongrong Cheng, Xiaofeng Wei, Yanting Zhang, Qian Zhang, Jianwei Xu, et al.
Molecules, 2023
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels T cell-related prognostic risk model and tumor immune microenvironment modulation in triple-negative breast cancer
Siyu Guo, Xinkui Liu, Jingyuan Zhang, Zhihong Huang, Peizhi Ye, et al.
Computers in Biology and Medicine, 2023
Integrated serum pharmacochemistry, 16S rRNA sequencing and metabolomics to reveal the material basis and mechanism of Yinzhihuang granule against non-alcoholic fatty liver disease
Yingying Tan, Zhihong Huang, Yingying Liu, Xiaojiaoyang Li, Antony Stalin, et al.
Journal of Ethnopharmacology, 2023
Biocontrol efficacy of apigenin isolated from Anisomeles indica (L.) Kuntze against immature stages of Culex quinquefasciatus (Say, 1823) and its in silico studies
Rajan Samuel, Ganesan Pathalam, Velmurugan Babu, Ragavendran Kamaraj, Mutheeswaran Subramanian, et al.
Biocatalysis and Agricultural Biotechnology, 2023
Inhibitory Effects of 2-Aminoethoxydiphenyl Borate (2-APB) on Three KV1 Channel Currents
Wei Zhao, Lanying Pan, Antony Stalin, Jianwei Xu, Liren Wu, et al.
Molecules, 2023
Gold Nanoparticles: Clinical Applications
Sheikdawood Parveen, T. Sathiyapriya, D. Tharani, S. U. Mohammed Riyaz, Rakshi Anuja Dinesh, et al.
Engineering Materials, 2023
Corrigendum: Revealing the mechanism of Huazhi Rougan granule in the treatment of nonalcoholic fatty liver through intestinal flora based on 16S rRNA, metagenomic sequencing and network pharmacology (Frontiers in Pharmacology, (2022), 13, (875700), 10.3389/fphar.2022.875700)
Yingying Liu, Yingying Tan, Jiaqi Huang, Chao Wu, Xiaotian Fan, et al.
Frontiers in Pharmacology, 2023
T cell-related prognostic risk model and tumor immune environment modulation in lung adenocarcinoma based on single-cell and bulk RNA sequencing
Jingyuan Zhang, Xinkui Liu, Zhihong Huang, Chao Wu, Fanqin Zhang, et al.
Computers in Biology and Medicine, 2023
An advanced network pharmacology study to explore the novel molecular mechanism of Compound Kushen Injection for treating hepatocellular carcinoma by bioinformatics and experimental verification
Shan Lu, Ziqi Meng, Yingying Tan, Chao Wu, Zhihong Huang, et al.
BMC Complementary Medicine and Therapies, 2022
Docking studies and thiourea-mediated reduced graphene oxide nanosheets' larvicidal efficacy against Culexquinquefasciatus
Babu Vimalanathan, Judith Vijaya John, Savarimuthu Ignacimuthu, Stalin Antony C, Magesh Daniel, et al.
Experimental Parasitology, 2022
Investigation on the efficiency of Brucea javanica oil emulsion injection with chemotherapy for treating malignant pleural effusion: A meta-analysis of randomized controlled trials
Rui Shi, Zhishan Wu, Haojia Wang, Jingyuan Zhang, Fanqin Zhang, et al.
Frontiers in Pharmacology, 2022
Therapeutic effects of shaogan fuzi decoction in rheumatoid arthritis: Network pharmacology and experimental validation
Lu Shi, Yiying Zhao, Chenran Feng, Feng Miao, Linlin Dong, et al.
Frontiers in Pharmacology, 2022
Single-Cell and Bulk RNA Sequencing Reveal Malignant Epithelial Cell Heterogeneity and Prognosis Signatures in Gastric Carcinoma
Zhihong Huang, Chao Wu, Xinkui Liu, Shan Lu, Leiming You, et al.
Cells, 2022
Identification of molecular mechanisms underlying the therapeutic effects of Xintong granule in coronary artery disease by a network pharmacology and molecular docking approach
Zhihong Huang, Siyu Guo, Changgeng Fu, Wei Zhou, Antony Stalin, et al.
Medicine United States, 2022
Mosquitocidal efficacy of embelin and its derivatives against Aedes aegypti L. and Culex quinquefasciatus Say. (Diptera: Culicidae) and computational analysis of acetylcholinesterase 1 (AChE1) inhibition
Antony Stalin, Appadurai Daniel Reegan, Munusamy Rajiv Gandhi, R.R Saravanan, Kedike Balakrishna, et al.
Computers in Biology and Medicine, 2022
Wearable Flexible Electronics Based Cardiac Electrode for Researcher Mental Stress Detection System Using Machine Learning Models on Single Lead Electrocardiogram Signal
Md Belal Bin Heyat, Faijan Akhtar, Syed Jafar Abbas, Mohammed Al-Sarem, Abdulrahman Alqarafi, et al.
Biosensors, 2022
Revealing the Mechanism of Huazhi Rougan Granule in the Treatment of Nonalcoholic Fatty Liver Through Intestinal Flora Based on 16S rRNA, Metagenomic Sequencing and Network Pharmacology
Yingying Liu, Yingying Tan, Jiaqi Huang, Chao Wu, Xiaotian Fan, et al.
Frontiers in Pharmacology, 2022
Influence of co-ligand on the biological properties of Schiff base metal complexes: Synthesis, characterization, cytotoxicity, and antimicrobial studies
Thamilarasan Vijayan, Jinheung Kim, Mohammad Azam, Saud I. Al‐Resayes, Antony Stalin, et al.
Applied Organometallic Chemistry, 2022
A novel strategy to reveal clinical advantages and molecular mechanism of aidi injection in the treatment of pancreatic cancer based on network meta-analysis and network pharmacology
Haojia Wang, Zhishan Wu, Yingying Liu, Miaomiao Wang, Antony Stalin, et al.
Journal of Ethnopharmacology, 2022
Revealing Calcium Signaling Pathway as Novel Mechanism of Danhong Injection for Treating Acute Myocardial Infarction by Systems Pharmacology and Experiment Validation
Siyu Guo, Yingying Tan, Zhihong Huang, Yikui Li, Weiyu Liu, et al.
Frontiers in Pharmacology, 2022
Synthesis, Molecular Docking and Mosquitocidal Efficacy of Lawsone and its Derivatives Against the Dengue Vector Aedes aegypti L. (Diptera: Culicidae)
Antony Stalin, Paul Dhivya, Ding Lin, Yue Feng, Antony Cruz Asharaja, et al.
Medicinal Chemistry, 2022
A New Strategy to Identify ceRNA-Based CCDC144NL-AS1/SERPINE1 Regulatory Axis as a Novel Prognostic Biomarker for Stomach Adenocarcinoma via High Throughput Transcriptome Data Mining and Computational Verification
Zhihong Huang, Xinkui Liu, Chao Wu, Shan Lu, Stalin Antony, et al.
Frontiers in Oncology, 2022
Genome-wide identification and evolution of WNK kinases in Bambusoideae and transcriptional profiling during abiotic stress in Phyllostachys edulis
RongXiu Liu, Naresh Vasupalli, Dan Hou, Antony Stalin, Hantian Wei, et al.
Peerj, 2022
Computational analysis of single nucleotide polymorphisms (SNPs) in PPAR gamma associated with obesity, diabetes and cancer
Antony Stalin, Ding Lin, Johnson Josephine Princy, Yue Feng, Haiping Xiang, et al.
Journal of Biomolecular Structure and Dynamics, 2022
An in-silico approach to identify the potential hot spots in SARS-CoV-2 spike RBD to block the interaction with ACE2 receptor
Antony Stalin, Ding Lin, Balakrishnan Senthamarai Kannan, Yue Feng, Yanjing Wang, et al.
Journal of Biomolecular Structure and Dynamics, 2022
Erratum to: Copper(ii) complexes supported by modified azo-based ligands: Nucleic acid binding and molecular docking studies (Open Chem. (2022) 20:1(505-516) DOI: 10.1515/chem-2022-0164)
Mamta Tripathi, Ashish Kumar Asatkar, Stalin Antony, Mrinal Kanti Dash, Gourisankar Roymahapatra, et al.
Open Chemistry, 2022
Copper(ii) complexes supported by modified azo-based ligands: Nucleic acid binding and molecular docking studies
Mamta Tripathi, Ashish Kumar Asatkar, Stalin Antony, Mrinal Kanti Dash, Gourisankar Roymahapatra, et al.
Open Chemistry, 2022
Exploring the Multicomponent Synergy Mechanism of Yinzhihuang Granule in Inhibiting Inflammation-Cancer Transformation of Hepar Based on Integrated Bioinformatics and Network Pharmacology
Jingyuan Zhang, Zhihong Huang, Xinkui Liu, Chao Wu, Wei Zhou, et al.
Biomed Research International, 2022
Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking
Jialin Li, Zhihong Huang, Shan Lu, Hua Luo, Yingying Tan, et al.
Medicine United States, 2021
Structure and pharmacological activities of polysaccharides from Anoectochilus roxburghii (Wall.) Lindl
Tong Wu, Shuailing Li, Yuqiu Huang, Zhen He, Ying Zheng, et al.
Journal of Functional Foods, 2021
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment validation
Chao Wu, Zhi-Hong Huang, Zi-Qi Meng, Xiao-Tian Fan, Shan Lu, et al.
Chinese Medicine United Kingdom, 2021
Investigation on the clinical efficacy and mechanism of compound kushen injection in treating esophageal cancer based on multi-dimensional network meta-analysis and in vitro experiment
Wei Zhou, Zhihong Huang, Chao Wu, Shan Lu, Changgeng Fu, et al.
Journal of Ethnopharmacology, 2021
An Advanced Systems Pharmacology Strategy Reveals AKR1B1, MMP2, PTGER3 as Key Genes in the Competing Endogenous RNA Network of Compound Kushen Injection Treating Gastric Carcinoma by Integrated Bioinformatics and Experimental Verification
Wei Zhou, Chao Wu, Chongjun Zhao, Zhihong Huang, Shan Lu, et al.
Frontiers in Cell and Developmental Biology, 2021
Investigation on the mechanisms of guiqi huoxue capsule for treating cervical spondylosis based on network pharmacology and molecular docking
Yingying Liu, Jingyuan Zhang, Xinkui Liu, Wei Zhou, Antony Stalin, et al.
Medicine United States, 2021
A Multidimensional Bayesian Network Meta-Analysis of Chinese Herbal Injections for Treating Non-small Cell Lung Cancer With Gemcitabine and Cisplatin
Mengwei Ni, Zhishan Wu, Haojia Wang, Wei Zhou, Chao Wu, et al.
Frontiers in Pharmacology, 2021
In vitro investigation of biophysical interactions between Ag(I) complexes of bis(methyl)(thia/selena)salen and ct-DNA via multi-spectroscopic, physicochemical and molecular docking methods along with cytotoxicity study
Mamta Tripathi, Rabbani Syed, Antony Stalin, Abdul Malik, Rama Pande, et al.
Luminescence, 2021
Hepatoprotective effect of selected isoandrographolide derivatives on steatotic HepG2 cells and High Fat Diet fed rats
Erenius Toppo, Naif Abdullah Al-Dhabi, Chinnakulandai Sankar, Sanmugapriya Nagul Kumar, Kanniappan Buvanesvaragurunathan, et al.
European Journal of Pharmacology, 2021
Physiochemical characterization and anti-carbapenemase activity of chitosan nanoparticles loaded Aegle marmelos essential oil against K. pneumoniae through DNA fragmentation assay
Govindan Rajivgandhi, Antony Stalin, Chelliah Chenthis Kanisha, Govindan Ramachandran, Natesan Manoharan, et al.
Surfaces and Interfaces, 2021
Mosquitocidal effect of monoterpene ester and its acetyl derivative from Blumea mollis (D. Don) Merr against Culex quinquefasciatus (Diptera: Culicidae) and their insilico studies
Sivanandhan Subramaniyan, Ganesan Pathalam, Stalin Antony, Gabriel Paulraj Michael, Rajan Samuel, et al.
Experimental Parasitology, 2021
Synthesis, absorption, emission and solvatochromic investigation of bioactive isatin tethered acridinedione conjugates
Govindasami Periyasami, Ponmurugan Karuppiah, Antony Stalin, Saradh Prasad, Mostafizur Rahaman, et al.
Materials Today Communications, 2021
Effect of monoterpene ester from Blumea axillaris (Lam.) DC and its acetyl derivative against plant pathogenic fungi and their in silico molecular docking
Subramaniyan Sivanandhan, Ganesan Pathalam, Stalin Antony, Gabriel Paulraj Michael, Kedike Balakrishna, et al.
Natural Product Research, 2021
Geranii herba as a potential inhibitor of SARS-CoV-2 main 3CLpro, spike RBD, and regulation of unfolded protein response: An in silico approach
Selvaraj Arokiyaraj, Antony Stalin, Balakrishnan Senthamarai Kannan, Hakdong Shin
Antibiotics, 2020
Synthesis of a 1,2,3-bistriazole derivative of embelin and evaluation of its effect on high-fat diet fed-streptozotocin-induced type 2 diabetes in rats and molecular docking studies
Antony Stalin, Subramani Kandhasamy, Balakrishnan Senthamarai Kannan, Rama Shanker Verma, Savarimuthu Ignacimuthu, et al.
Bioorganic Chemistry, 2020
Anti-methanogenic effect of rhubarb (Rheum spp.) – An in silico docking studies on methyl-coenzyme M reductase (MCR)
Selvaraj Arokiyaraj, Antony Stalin, Hakdong Shin
Saudi Journal of Biological Sciences, 2019
A competent synthesis and efficient anti-inflammatory responses of isatinimino acridinedione moiety via suppression of in vivo NF-κB, COX-2 and iNOS signaling
Govindasami Periyasami, Paulrayer Antonisamy, Karthikeyan Perumal, Antony Stalin, Mostafizur Rahaman, et al.
Bioorganic Chemistry, 2019
Effect of tiliamosine, a bis, benzylisoquinoline alkaloid isolated from Tiliacora acuminata (Lam.) Hook. f. & Thom on the immature stages of filarial mosquito Culex quinquefasciatus say (Diptera: Culicidae)
Sylvester Darvin Sandhanam, Ganesan Pathalam, Stalin Antony, Rajan Samuel, Gabriel Paulraj Michael, et al.
Experimental Parasitology, 2019
Glucosamine-6-phosphate synthase inhibiting C3-β-cholesterol tethered spiro heterocyclic conjugates: Synthesis and their insight of DFT and docking study
Govindasami Periyasami, Subban Kamalraj, Ramanathan Padmanaban, Santhakumar Yeswanth Kumar, Antony Stalin, et al.
Bioorganic Chemistry, 2019
Hepatoprotective effect of bisbenzylisoquinoline alkaloid tiliamosine from Tiliacora racemosa in high-fat diet/diethylnitrosamine-induced non-alcoholic steatohepatitis
S. Sylvester Darvin, Erenius Toppo, S. Esakkimuthu, T.P. Ajeesh Krishna, S. Antony Ceasar, et al.
Biomedicine and Pharmacotherapy, 2018
Curative effect of arjunolic acid from Terminalia arjuna in non-alcoholic fatty liver disease models
Erenius Toppo, S. Sylvester Darvin, S. Esakkimuthu, K. Buvanesvaragurunathan, T.P. Ajeesh Krishna, et al.
Biomedicine and Pharmacotherapy, 2018
Biocontrol and non-target effect of fractions and compound isolated from Streptomyces rimosus on the immature stages of filarial vector Culex quinquefasciatus Say (Diptera: Culicidae) and the compound interaction with Acetylcholinesterase (AChE1)
Pathalam Ganesan, Antony Stalin, Micheal Gabriel Paulraj, Kedike Balakrishna, Savarimuthu Ignacimuthu, et al.
Ecotoxicology and Environmental Safety, 2018
Effect of compound isolated from Lawsonia inermis (L.) (Myrtales: Lythraceae) on the immature stages of filarial vector Culex quinquefasciatus Say (Diptera: Culicidae) and its docking analysis with Acetylcholinesterase (AChE1)
Sylvester Darvin Sandhanam, Pathalam Ganesan, Antony Stalin, Gabriel Paulraj Michael, Kedike Balakrishna, et al.
Biocatalysis and Agricultural Biotechnology, 2018
Synthesis of novel β-amino alcohols from phenylacetylcarbinol: cytotoxicity activity against A549 cells and molecular docking
Prabhu Mahendran, A. Jeya Rajendran, C. Balachandran, A. Stalin, Saravanan Rangan, et al.
Research on Chemical Intermediates, 2018
Exploration of cell cycle regulation and modulation of the DNA methylation mechanism of pelargonidin: Insights from the molecular modeling approach
Natesan Karthi, Arumugasamy Karthiga, Thangaraj Kalaiyarasu, Antony Stalin, Vaiyapuri Manju, et al.
Computational Biology and Chemistry, 2017
Antihyperlipidemic and hepatoprotective effects of Gardenin A in cellular and high fat diet fed rodent models
Erenius Toppo, S. Sylvester Darvin, S. Esakkimuthu, A. Stalin, K. Balakrishna, et al.
Chemico Biological Interactions, 2017
Myoinositol ameliorates high-fat diet and streptozotocin-induced diabetes in rats through promoting insulin receptor signaling
Poovathumkal James Antony, Gopalsamy Rajiv Gandhi, Antony Stalin, Kedike Balakrishna, Erenius Toppo, et al.
Biomedicine and Pharmacotherapy, 2017
Protective effects of Ficus carica leaves on glucose and lipids levels, carbohydrate metabolism enzymes and β-cells in type 2 diabetic rats
Santiagu Stephen Irudayaraj, Sunil Christudas, Stalin Antony, Veeramuthu Duraipandiyan, Al-Dhabi Naif Abdullah, et al.
Pharmaceutical Biology, 2017
Identifying potential PPARγ agonist/partial agonist from plant molecules to control type 2 diabetes using in silico and in vivo models
Antony Stalin, Santiagu Stephen Irudayaraj, Dhandapani Ramesh Kumar, Kedike Balakrishna, Savarimuthu Ignacimuthu, et al.
Medicinal Chemistry Research, 2016
Antioxidant, antilipidemic and antidiabetic effects of ficusin with their effects on GLUT4 translocation and PPARγ expression in type 2 diabetic rats
Santiagu Stephen Irudayaraj, Antony Stalin, Christudas Sunil, Veeramuthu Duraipandiyan, Naif Abdullah Al-Dhabi, et al.
Chemico Biological Interactions, 2016
In silico molecular docking of niloticin with acetylcholinesterase 1 (AChE1) of Aedes aegypti L. (Diptera: Culicidae): a promising molecular target
Appadurai Daniel Reegan, Antony Stalin, Michael Gabriel Paulraj, Kedike Balakrishna, Savarimuthu Ignacimuthu, et al.
Medicinal Chemistry Research, 2016
Hypoglycemic activity of 6-bromoembelin and vilangin in high-fat diet fed-streptozotocin-induced type 2 diabetic rats and molecular docking studies
Antony Stalin, Santiagu Stephen Irudayaraj, Gopalsamy Rajiv Gandhi, Kedike Balakrishna, Savarimuthu Ignacimuthu, et al.
Life Sciences, 2016
In silico docking analysis to explore the proapoptotic and anti cell proliferative potential of ferulic acid
Indian Journal of Biochemistry and Biophysics, 2016
Isolation and characterization of Anthraquinone from Streptomyces sp. ERINLG-26 with anticancer activity Against adenocarcinoma cell line COLO320
C. Balachandran, V. Duraipandiyan, N. A. Al-Dhabi, A. Stalin, K. Balakrishna, et al.
Applied Biochemistry and Microbiology, 2015
γ-sitosterol a potent hypolipidemic agent: In silico docking analysis
Rangachari Balamurugan, Antony Stalin, Adithan Aravinthan, Jong-Hoon Kim
Medicinal Chemistry Research, 2015
Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARγ in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway
Gopalsamy Rajiv Gandhi, Gnanasekaran Jothi, Poovathumkal James Antony, Kedike Balakrishna, Michael Gabriel Paulraj, et al.
European Journal of Pharmacology, 2014
Polyphenols-rich Cyamopsis tetragonoloba (L.) Taub. beans show hypoglycemic and β-cells protective effects in type 2 diabetic rats
Gopalsamy Rajiv Gandhi, Pautu Vanlalhruaia, Antony Stalin, Santiagu Stephen Irudayaraj, Savarimuthu Ignacimuthu, et al.
Food and Chemical Toxicology, 2014
Insulin sensitization via partial agonism of PPARγ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin in type 2 diabetic rats
Gopalsamy Rajiv Gandhi, Antony Stalin, Kedike Balakrishna, Savarimuthu Ignacimuthu, Michael Gabriel Paulraj, et al.
Biochimica Et Biophysica Acta General Subjects, 2013
Molecular docking of γ-sitosterol with some targets related to diabetes
Rangachari Balamurugan, Antony Stalin, Savarimuthu Ignacimuthu
European Journal of Medicinal Chemistry, 2012

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