Surfacehcm

@surfacehcm.vn

Surfacehcm



                                                     

https://researchid.co/surfacehcm

Surfacehcm - Địa điểm uy tín mua bán các sản phẩm công nghệ: Máy tính Microsoft Surface, phụ kiện công nghệ chính hãng, uy tín, giá tốt nhất thị trường, cam kết hàng luôn có sẵn.

Surfacehcm
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47832

Scholar Citations

109

Scholar h-index

282

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation
    C Liu, A Karabina, A Meller, A Bhattacharjee, CJ Agostino, GR Bowman, ...
    Proceedings of the National Academy of Sciences 121 (9), e2315472121 2024

  • One must reconstitute the functions of interest from purified proteins
    JA Spudich
    Frontiers in Physiology 15, 1390186 2024

  • Broad therapeutic benefit of myosin inhibition in hypertrophic cardiomyopathy
    L Sen Martin, A Fernandez Trasancos, MA Lopez Unzu, D Pathak, ...
    bioRxiv, 2024.03. 22.584986 2024

  • Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically
    N Nandwani, D Bhowmik, MC Childers, RR Goluguri, A Dawood, ...
    bioRxiv, 2024.02. 29.582851 2024

  • Motility Assay to Probe the Calcium Sensitivity of Myosin and Regulated Thin Filaments
    C Liu, KM Ruppel, JA Spudich
    Familial Cardiomyopathies: Methods and Protocols, 169-189 2023

  • Cryo-electron tomography reveals the structural diversity of cardiac proteins in their cellular context
    RA Woldeyes, M Nishiga, AS Vander Roest, L Engel, P Giri, ...
    bioRxiv 2023

  • Abstract EC. 03: Distinct Molecular Signatures Of HCM-And DCM-causing Mutations At The Same Residue In The Transducer Of Cardiac Myosin
    M Kawana, RR Goluguri, A Dawood, JA Spudich, K Ruppel
    Circulation Research 133 (Suppl_1), AEC. 03-AEC. 03 2023

  • Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients
    S Nag, SK Gollapudi, CL Del Rio, JA Spudich, R McDowell
    Science Advances 9 (30), eabo7622 2023

  • Homologous mutations in [... formula...], embryonic, and perinatal muscle myosins have divergent effects on molecular power generation
    C Liu, A Karabina, A Meller, A Bhattacharjee, CJ Agostino, GR Bowman, ...
    bioRxiv 2023

  • Structural changes in myosin affect chemo-mechanical properties of the myosin-actin interaction
    D Pathak, N Nandwani, JA Spudich, K Ruppel
    Biophysical Journal 122 (3), 147a 2023

  • Changes in myosin biomechanics influence growth and maturation of iPSC-cardiomyocytes
    D Bernstein, AS Vander Roest, S Wu, B Pruitt, M Zhao, G Fajardo, ...
    Biophysical Journal 122 (3), 148a 2023

  • Sarcomere dynamics simulations to uncover mechanisms in hypertrophic cardiomyopathy
    AS Vander Roest, JA Spudich, K Ruppel, M Regnier, D Bernstein
    Biophysical Journal 122 (3), 148a-149a 2023

  • Molecular characterization of a novel MYH7 mutation Q222H in a patient with severe dilated cardiomyopathy
    M Kawana, RR Goluguri, A Dawood, JA Spudich, K Ruppel
    Biophysical Journal 122 (3), 258a 2023

  • Cryo-EM structure of the folded-back state of human β-cardiac myosin
    A Grinzato, D Auguin, C Kikuti, N Nandwani, D Moussaoui, D Pathak, ...
    Biophysical Journal 122 (3), 258a-259a 2023

  • Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration
    S Lee, AS Vander Roest, C Blair, K Kao, SB Bremner, MC Childers, ...
    bioRxiv, 2023.06. 08.544276 2023

  • Hypertrophic cardiomyopathy: mutations to mechanisms to therapies
    M Kawana, JA Spudich, KM Ruppel
    Frontiers in Physiology 13, 975076 2022

  • A small-molecule myosin inhibitor as a targeted multi-stage antimalarial
    DV Trivedi, A Karabina, G Bergnes, A Racca, H Wander, S Jung, N Mittal, ...
    bioRxiv, 2022.09. 09.507317 2022

  • Hypertrophic cardiomyopathy mutations in the pliant and light chain-binding regions of the lever arm of human β-cardiac myosin have divergent effects on myosin function
    MM Morck, D Bhowmik, D Pathak, A Dawood, J Spudich, KM Ruppel
    Elife 11, e76805 2022

  • Allosteric destabilization of the super-relaxed state of cardiac myosin by hypertrophic cardiomyopathy-causing mutations
    N Nandwani, D Bhowmik, A Dawood, K Ruppel, JA Spudich
    Biophysical Journal 121 (3), 292a 2022

  • First-in-class drug candidate (MPH-220) efficiently improves spastic gait disorders by selective inhibition of fast skeletal muscle myosin-2
    M Gyimesi, AI Horvath, D Turos, SK Suthar, M Penzes, L Canon, C Kikuti, ...
    Biophysical Journal 121 (3), 291a 2022

MOST CITED SCHOLAR PUBLICATIONS

  • The regulation of rabbit skeletal muscle contraction: I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of
    JA Spudich, S Watt
    Journal of biological chemistry 246 (15), 4866-4871 1971
    Citations: 5486

  • Single myosin molecule mechanics: piconewton forces and nanometre steps
    JT Finer, RM Simmons, JA Spudich
    Nature 368 (6467), 113-119 1994
    Citations: 2433

  • Disruption of the Dictyostelium Myosin Heavy Chain Gene by Homologous Recombination
    A De Lozanne, JA Spudich
    Science 236 (4805), 1086-1091 1987
    Citations: 1187

  • Fluorescent actin filaments move on myosin fixed to a glass surface.
    SJ Kron, JA Spudich
    Proceedings of the National Academy of Sciences 83 (17), 6272-6276 1986
    Citations: 1099

  • Optimized localization analysis for single-molecule tracking and super-resolution microscopy
    KI Mortensen, LS Churchman, JA Spudich, H Flyvbjerg
    Nature methods 7 (5), 377-381 2010
    Citations: 1010

  • Myosin-V is a processive actin-based motor
    AD Mehta, RS Rock, M Rief, JA Spudich, MS Mooseker, RE Cheney
    Nature 400 (6744), 590-593 1999
    Citations: 978

  • Single-molecule biomechanics with optical methods
    AD Mehta, M Rief, JA Spudich, DA Smith, RM Simmons
    Science 283 (5408), 1689-1695 1999
    Citations: 927

  • Quantitative measurements of force and displacement using an optical trap
    RM Simmons, JT Finer, S Chu, JA Spudich
    Biophysical journal 70 (4), 1813-1822 1996
    Citations: 721

  • Myosin subfragment-1 is sufficient to move actin filaments in vitro
    YY Toyoshima, SJ Kron, EM McNally, KR Niebling, C Toyoshima, ...
    Nature 328 (6130), 536-539 1987
    Citations: 652

  • Nonmuscle contractile proteins: the role of actin and myosin in cell motility and shape determination
    M Clarke, JA Spudich
    Annual review of biochemistry 46 (1), 797-822 1977
    Citations: 644

  • Myosin structure and function in cell motility
    HM Warrick, JA Spudich
    Annual review of cell biology 3 (1), 379-421 1987
    Citations: 639

  • A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice
    EM Green, H Wakimoto, RL Anderson, MJ Evanchik, JM Gorham, ...
    Science 351 (6273), 617-621 2016
    Citations: 609

  • Movement of myosin-coated fluorescent beads on actin cables in vitro
    MP Sheetz, JA Spudich
    Nature 303 (5912), 31-35 1983
    Citations: 598

  • How molecular motors work
    JA Spudich
    Nature 372 (6506), 515-518 1994
    Citations: 597

  • The neck region of the myosin motor domain acts as a lever arm to generate movement.
    TQ Uyeda, PD Abramson, JA Spudich
    Proceedings of the National Academy of Sciences 93 (9), 4459-4464 1996
    Citations: 577

  • Myosin step size: estimation from slow sliding movement of actin over low densities of heavy meromyosin
    TQP Uyeda, SJ Kron, JA Spudich
    Journal of molecular biology 214 (3), 699-710 1990
    Citations: 554

  • Myosin-V stepping kinetics: a molecular model for processivity
    M Rief, RS Rock, AD Mehta, MS Mooseker, RE Cheney, JA Spudich
    Proceedings of the National Academy of Sciences 97 (17), 9482-9486 2000
    Citations: 502

  • [33] Assays for actin sliding movement over myosin-coated surfaces
    SJ Kron, YY Toyoshima, TQP Uyeda, JA Spudich
    Methods in enzymology 196, 399-416 1991
    Citations: 497

  • Cytoskeletal elements of chick embryo fibroblasts revealed by detergent extraction
    S Brown, W Levinson, JA Spudich
    Journal of supramolecular structure 5 (2), 119-130 1976
    Citations: 475

  • Myosin VI is a processive motor with a large step size
    RS Rock, SE Rice, AL Wells, TJ Purcell, JA Spudich, HL Sweeney
    Proceedings of the National Academy of Sciences 98 (24), 13655-13659 2001
    Citations: 458