Hafsat Rufai Ahmad

RESEARCH, TEACHING, or OTHER INTERESTS

Pediatrics, Perinatology and Child Health, Hematology, Public Health, Environmental and Occupational Health, Oncology

Scopus Publications

Binder and disintegrant performance of native and thermally modified dioscorea cayenensis starches in paracetamol tablet formulations
, Usaini Dauda, Garba Khalid, , Hassan Musa, Partap Bhatia, , Mohammed Hassan, , Abdurrahman Yola,et al.
University of Benin
The versatility of starch as pharmaceutical excipient is gaining attention in the development of natural polymers for application in tablet formulations. In this study, we reported the binder and disintegrant properties of native and modified starches extracted from Dioscorea cayenensis . The extracted starch was modified by pregelatinization (PGS1) and ethanol dehydrated pregelatinization (PGS2) and was employed as binder and disintegrant in paracetamol tablet formulations via wet granulation. Two-way analysis of variance indicated significant differences between tablet properties, measured in terms of hardness, friability and disintegration time, with respect to the starch type and concentration. Multiple comparison computed using Bonferroni post-hoc analysis indicated higher values of tablet hardness in PGS2 than PGS1 and unmodified starch (UMS) ( p <0.01). UMS had the highest friability implying poor mechanical quality (Friability >3%). At 2-7% concentrations, PGS1, PGS2 and UMS demonstrated acceptable United State Pharmacopoeial disintegration time profiles for uncoated tablets. Overall results demonstrated an improved quality of the modified starches compared to the UMS with the potential application of PSG1 as binder and disintegrant in different ratios for immediate release tablet formulation. PSG2 was shown to make a good binder when sustained-release of API is required.


Evaluation of acid hydrolysed starch derived from Digitaria iburua as binder




Preparation and characterization of dialdehyde starch and its' cross-linking with copper (II) ion




Breast-cancer screening with trained volunteers in a rural area of Sudan: A pilot study
Dafalla Omer Abuidris, Ahmed Elsheikh, Majdeldien Ali, Hassan Musa, Elgaili Elgaili, Anas O Ahmed, Imadeldien Sulieman, and Sulma Ibrahim Mohammed
Elsevier BV



Formulation and evaluation of ascorbic acid tablets by direct compression using microcrystalline starch as a direct compression excipient




Evaluation of finger millet (Eleusine coracana) starch as a binder in high dose tablets




Evaluaton of barley hordeum vulgare starch as tablet disintegrant




Assessment of physicochemical properties of metronidazole tablets marketed in Zaria, Nigeria




Studies on some physicochemical properties of native and modified starches from digitaria iburua and Zea mays




Evaluation of the glidant property of Fonio starch




Evaluation of the powder and compaction properties of microcrystalline starch (MCS) derived from cassava (Manihot Esculenta Crantz) starch by enzymatic hydrolysis




Determination of arsenic concentration in well and borehole waters in Zaria, Nigeria
H. Musa, I.A. Yakasai, K.Y. Musa, A.B. Isah, and K. Mshelbwala
Science Alert



The concentration of cadmium in borehole and well waters in Zaria, Nigeria
H. Musa, I.A Yakasai, H.H. Musa, K.Y Musa, and M.S. Gwarzo
Science Alert



Toxicity studies on the methanolic extract of Portulaca oleracea L. (Fam. Portulacaceae)
K.Y. Musa, A. Ahmed, G. Ibrahim, O.E. Ojonugwa, M. Bisalla, H. Musa, and U.H. Danmalam
Science Alert



Prevalence of sexually transmitted diseases (STD) among women in a suburban Sudanese community




Antimicrobial agent resistance in bacterial isolates from patients with diarrhea and urinary tract infection in the Sudan
A A Ahmed, Z Karrar, H S Hassan, A B Ahmed, H A Musa, H Osman, and A M Mansour
American Society of Tropical Medicine and Hygiene
Antimicrobial sensitivity tests were performed on four-hundred and ninety-seven bacterial isolates from Sudanese patients with diarrhea or urinary tract infections. Shigella dysenteriae type I and enteropathogenic Escherichia coli showed high resistance rates (percentage of isolates showing antibiotic resistance) against the commonly-used antimicrobial agents: ampicillin, amoxicillin, chloramphenicol, tetracycline, cotrimoxazole, nalidixic acid, sulfonamide, and neomycin, and were completely sensitive to ciprofloxacin. Eighteen resistance patterns against nine antimicrobial agents tested were observed in enteric pathogens. Resistance to ampicillin, amoxicillin, tetracycline, cotrimoxazole, and sulfonamide was the most frequent pattern. The common urinary pathogens, E. coli, Klebsiella pneumoniae, and Proteus mirabilis showed high rates of resistance to ampicillin, amoxicillin, cotrimoxazole, tetracycline, sulfonamide, trimethoprim, streptomycin, and carbenicillin. We recommend that physicians seek updated knowledge of the common antibiotic-sensitivity patterns when starting empirical antibiotic therapy in Sudanese patients with diarrhea or urinary tract infection.


First report of MRSA from hospitalized patients in Sudan [4]




Water quality and public health in northern Sudan: A study of rural and peri-urban communities
H. A. Musa, P. Shears, S. Kafi, and S. K. Elsabag
Oxford University Press (OUP)
Access to adequate supplies of good quality drinking water continues to be limited among many rural and peri‐urban communities in Africa, despite several decades of water improvement programmes. The present study investigated water quality at the source and point of consumption among rural and peri‐urban communities in northern Sudan. Faecal coliform counts were determined by the membrane filtration technique and geometric mean counts compared in different seasons and among the different communities. Among nomadic pastoralists and riverine villages, both water sources and water stored for consumption had faecal coliform counts grossly in excess of WHO standards, with higher counts at the end of the rainy season. In the peri‐urban community on the outskirts of Omdurman, while water quality from the distribution system had faecal coliform counts generally below 10 dl−1, after storage, water was of considerably lower quality, with faecal coliform counts up to 1000 d1−1. The highest counts again occurred in the rainy season. Rates of diarrhoeal disease for Khartoum province were also greatest towards the end of the rainy season. The study has shown that poor quality water continues to be a major risk factor for public health in these communities.


Antibiotic resistant Escherichia coli in a Sudanese hospital [2]
H.A. Musa and P. Shears
Elsevier BV



Occurrence in Sudan of Shigella dysenteriae type 1 with transferable antimicrobial resistance
H. A. Musa, H. S. Hassan, and P. Shears
Informa UK Limited

RECENT SCHOLAR PUBLICATIONS

Design and Implementation of a Sickle Cell Disease Electronic Registry in Resource Limited Setting in Nigeria—A Pilot Study
MA Idris, L Ruggieri, HR Ahmad, A Hassan, IN Ibrahim, FJ Adullahi, ...
Hemato 5 (3), 340-349 2024



The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria
OO Ojewunmi, TA Adeyemo, AI Oyetunji, B Inyang, A Akinrindoye, ...
Human Molecular Genetics 33 (10), 919-929 2024



Quality of Life as a Predictor of Childhood Cancer Treatment Abandonment
JF Abdullahi, SU Abdullahi, Y Abubakar, MN Adebiyi, HR Ahmad
Journal of Medical and Basic Scientific Research 4 (3-4) 2023



Prevalence and pattern of sensorineural hearing loss among children and adolescents with sickle cell disease in a tertiary health facility, Northwest Nigeria
A Solomon, SN Adebola, I Abdulkadir, H Ahmad, MI Babatunde, ...
Annals of African Medical Research 6 (1) 2023



Intellectual disability is a very common co-morbid condition among children with previously untreated epilepsy in northern Nigeria
E Trevathan, M Umar, AT Abdullahi, AO Kalu, HB Salihu, H Yakubu, ...
EPILEPSIA 64, 535-536 2023



Epilepsy diagnostic accuracy by epilepsy-trained community health workers compared to community physicians: results from the BRIDGE non-inferiority cluster randomized clinical
AT Abdullahi, U Sabo, H Ahmad, F Nuhu, H Adamu, L Habiba, A Ibrahim, ...
EPILEPSIA 64, 102-103 2023



Clinico-demographic characteristics, morbidity and mortality patterns of sickle cell disease in a tertiary institution
JA Faruk, MN Adebiyi, HR Ahmad
Sahel Medical Journal 25 (2), 52-56 2022



Epilepsy education via Hausa-language radio broadcasts: a key component of Bridging the Childhood Epilepsy Treatment Gap in Africa (BRIDGE) project
AS Salihu, A Taura, H Ahmad, F Nuhu, I Sodangi, H Adamu, U Sabo, ...
EPILEPSIA 62, 180-181 2021



Bridging the childhood epilepsy treatment Gap in Africa (BRIDGE): A cluster randomized clinical trial of task-shifted epilepsy care
A Taura, H Ahmad, F Nuhu, U Sabo, H Adamu, I Sodangi, M Aliyu, ...
EPILEPSIA 62, 23-24 2021



The Childhood Epilepsy Treatment Gap in Northern Nigeria
E Trevathan, A Taura, H Ahmad, F Nuhu, AS Salihu, H Adamu, UA Sabo, ...
ANNALS OF NEUROLOGY 90, S127-S127 2021



Screening for neurodevelopmental disorders among children with untreated epilepsy in Northern Nigeria
E Trevathan, A Taura, H Ahmad, F Nuhu, U Sabo, H Adamu, A Salihu, ...
Journal of the Neurological Sciences 429 2021



Childhood leukemia outcomes in a low-resource tertiary care setting
JA Faruk, NM Adebiyi, HR Ahmad
The Egyptian Journal of Haematology 46 (3), 170-174 2021



Comparison of Three Biomarkers with Blood Culture Yield in Children with Sickle Cell Anaemia at an Acute Care Tertiary Setting of North-Western Nigeria
JA Faruk, S Aliyu, MN Adebiyi, Y Abubakar, HA Abdulrauf, M Ibrahim, ...
Journal of Medical and Basic Scientific Research 2 (1), 37-43 2021



Chronic Myeloid Leukaemia in A 6-Year Old Nigerian Girl Treated with a Tyrosine Kinase Inhibitor: A Case Report
JA Faruk, MN Adebiyi, HA Abdulrauf, AD Waziri, HR Ahmad
Tropical Journal of Health Sciences 28 (2), 49-52 2021



The use of Virtual Media in Postgraduate Medical Training during the COVID-19 Pandemic: Experience from a Resource-Constrained Setting
JA Faruk, Y Abubakar, HR Ahmad, A Isa
The Nigerian Journal of General Practice 19 (1), 27-31 2021



Challenges of Managing Childhood Cancers in Resource-Constrained Settings: A Case of Sarcoma Botryoides in a 3-Year-Old Girl
Y Abubakar, JA Faruk, HR Ahmad, DE Suleiman
Annals of Tropical Pathology 11 (2), 193-195 2020



Hematological parameters of children with sickle cell anemia in steady and crisis states in Zaria, Nigeria
Y Abubakar, HR Ahmad, JA Faruk
Annals of Tropical Pathology 10 (2), 122-125 2019



Giant congenital melanocytic nevi: case report and review of literature
Y Abubakar, HR Ahmad, JA Faruk
Sub-Saharan African Journal of Medicine 5 (4), 138-141 2018



The use of hydroxycarbamide in children with sickle cell anemia
HR Ahmad, JA Faruk, AM Sobowale, A Solomon, AN Mustapha, ...
Sahel Medical Journal 21 (4), 189-193 2018



Carcinoma of the colon in a child
HR Ahmad, JA Faruk, TT Sholadoye, AJ Mohammed, HO Aliyu, SM Mado, ...
Journal of Community and Supportive Oncology 16 (3), E152-E155 2018

MOST CITED SCHOLAR PUBLICATIONS

Pattern and outcomes of childhood malignancies at Ahmadu bello university teaching hospital, Zaria
HR Ahmad, JA Faruk, M Abdullahi, AA Olorunkooba, H Ishaku, ...
Sub-Saharan African Journal of Medicine 3 (3), 127-131 2016
Citations: 19



Hematological parameters of children with sickle cell anemia in steady and crisis states in Zaria, Nigeria
Y Abubakar, HR Ahmad, JA Faruk
Annals of Tropical Pathology 10 (2), 122-125 2019
Citations: 14



The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria
OO Ojewunmi, TA Adeyemo, AI Oyetunji, B Inyang, A Akinrindoye, ...
Human Molecular Genetics 33 (10), 919-929 2024
Citations: 7



Evaluation of the cognitive effect of newborn resuscitation training on health-care workers in selected states in Northern Nigeria
LW Umar, HRI Ahmad, A Isah, HW Idris, L Hassan, FL Abdullahi, I Hassan, ...
Annals of African medicine 17 (1), 33-39 2018
Citations: 7



Typhoid fever in children presenting to paediatric medical wards of Ahmadu Bello University Teaching Hospital Zaria: a 13-month review
LW Umar, H Adelaiye, M Adebiyi, GO Adeoye, HR Ahmad, F Giwa
Nigerian Journal of Paediatrics 40 (3), 211-216 2013
Citations: 6



Carcinoma of the colon in a child
HR Ahmad, JA Faruk, TT Sholadoye, AJ Mohammed, HO Aliyu, SM Mado, ...
Journal of Community and Supportive Oncology 16 (3), E152-E155 2018
Citations: 5



Assessment of tuberculin reactivity of BCG-vaccinated infants in Zaria, Nigeria
MJ Gambo, UM Lawan, HR Ahmad, WN Ogala
Nigerian Journal of Basic and Clinical Sciences 11 (2), 104-109 2014
Citations: 4



The use of hydroxycarbamide in children with sickle cell anemia
HR Ahmad, JA Faruk, AM Sobowale, A Solomon, AN Mustapha, ...
Sahel Medical Journal 21 (4), 189-193 2018
Citations: 3



Giant congenital melanocytic nevi: case report and review of literature
Y Abubakar, HR Ahmad, JA Faruk
Sub-Saharan African Journal of Medicine 5 (4), 138-141 2018
Citations: 2



Clinico-demographic characteristics, morbidity and mortality patterns of sickle cell disease in a tertiary institution
JA Faruk, MN Adebiyi, HR Ahmad
Sahel Medical Journal 25 (2), 52-56 2022
Citations: 1



Childhood leukemia outcomes in a low-resource tertiary care setting
JA Faruk, NM Adebiyi, HR Ahmad
The Egyptian Journal of Haematology 46 (3), 170-174 2021
Citations: 1



The management of stroke in sickle cell anemia: A single site experience in a low-income setting
JA Faruk, HR Ahmad, GO Ogunrinde, NH Usman
Sub-Saharan African Journal of Medicine 4 (1), 3-8 2017
Citations: 1



Sarcomatoid renal cell carcinoma in an adolescent with sickle cell anaemia
HR Ahmad, JA Faruk, MA Bugaje, A Solomon, MOA Samaila, RM Akuse
Case Reports in Oncological Medicine 2017 (1), 2129450 2017
Citations: 1