Thirukkumar

@amrita.edu

Assistant Professor (Food Science)
Amrita School of Agricultural Sciences

Thirukkumar


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https://researchid.co/thirukkumar

RESEARCH, TEACHING, or OTHER INTERESTS

Food Science, Horticulture, Nutrition and Dietetics, Plant Science
14

Scopus Publications

392

Scholar Citations

8

Scholar h-index

6

Scholar i10-index

Scopus Publications

  • Study on various green aqueous extraction techniques for extracting cottonseed milk to improve nutritional quality
    Thirukkumar Subramani, Hemalatha Ganapathyswamy, Vellaikumar Sampathrajan, UmaMaheswari Thiyagamoorthy
    Journal of Cotton Research, 2026
    Background Plant-based milk is in demand worldwide due to issues such as lactose intolerance, milk allergies, and the environmental impact of dairy farming. Gossypol, which is toxic at certain levels, underutilizes cottonseed for human consumption, despite its high protein and oil contents for emulsion formation. The nutrient contents and interaction of gossypol with protein compounds of the different extracted cottonseed milk samples from modified aqueous extraction (MAE), ultrasonic-assisted aqueous extraction (UAAE), enzymatic-assisted aqueous extraction (EAAE), and conventional aqueous extraction (CAE) methods were analyzed. Results The extraction techniques substantially affected the protein levels and amino acid composition of the milk samples, whereas the fatty acid profile content remained unaltered. Additionally, physicochemical properties such as extraction yield, viscosity, color values, and total acidity are significantly influenced by the extraction methods. The crude protein, crude fat, and gossypol content in the extracted cottonseed milk samples ranged from 2.44 to 3.52 g per 100 mL, 1.594 to 2.953 g per 100 mL, and 42.0 to 67.3 mg·kg −1 (wet basis), respectively. Fourier transform infrared spectroscopy (FTIR) spectra revealed α-helix bands at 1 656.74 cm⁻ 1 in CAE, MAE, and UAAE, and at 1 659.63 cm⁻ 1 in EAAE, indicating alterations in gossypol levels and amine/amide group intensities. EAAE cottonseed milk presented the highest protein and crude fat contents, as well as superior total phenology, flavonoid, and antioxidant activities, making it the most nutritious among all approaches. Conclusions The cottonseed milk samples from the adopted treatments provided the right amount of nutrients and permissible levels of gossypol for human consumption. This study highlights the potential use of cottonseed as a cottonseed-based milk by using the EAAE extraction method, which effectively mitigates gossypol toxicity while preserving essential nutrients and bioactive compounds. The results provide a foundation for future research into the nutritional and functional properties of cottonseed milk as a potential plant-based milk source and alternative dairy system. Graphical Abstract
  • Effect of optimized germination on nutritional functional and phytochemical characteristics of green gram
    Thirukkumar Subramani, Sivasankari Ruckmangathan, Hemalatha Ganapathyswamy, Sivasubramanin Palanisamy, Murugesan Palaniappan, et al.
    Scientific Reports, 2026
  • Deciphering the Significance of Millets as a Superfood in Promoting Gut Health: A Review
    Uma Maheswari Thiyagamoorthy, Sujitha Palanisamy, Jeyakumar Saranya Packialakshmi, Geethanjali Sadayandi, Karpagapandi Lakshmanan, et al.
    Food Reviews International, 2026
  • Therapeutic and Environmental Potential of Mushrooms in Ancient and Modern Contexts: A Review
    Parthasarathy Seethapathy, Thirukkumar Subramani, Nadir Ayrilmis, Hrishikesh Patil
    International Journal of Medicinal Mushrooms, 2025
    Mushrooms are the healthiest, safest, most nutritious foods and are vital to human well-being. In historical contexts, religious teachings influenced the treatment of diseases, with ethnomycological knowledge suggesting that mushrooms held divine clues due to their unique appearances. The use of mushrooms was often linked to the "doctrine of signatures," where their morphological resemblance to human organs, such as the ear, kidney, and lungs, prompted researchers to theorize that products derived from mushrooms might be effective in treating health concerns. A wide variety of edible and wild mushrooms are now recognized for their bioactive compounds, which are valuable in biopharmaceuticals and dietary supplements. The compounds exhibit a range of therapeutic properties, encompassing immune enhancement, antioxidant effects, anti-inflammatory actions, antiviral capabilities, and anti-neoplastic activities. Modern science has corroborated many of these traditional insights, revealing mushrooms as sources of bioactive compounds with therapeutic potential. The intertwined filamentous mycelium of mushrooms is also attracting interest for its biocomposite uses in sustainable and environmentally friendly businesses. Biocomposite materials suitable for construction and building applications can be produced by creating a mycelial matrix or a self-forming adhesive using non-food fungal mycelia flour. This review explores the ethnomycological background, therapeutic potential, and innovative uses of mushroom mycelium in biocomposites, highlighting their role in health, wellness, and sustainable development.
  • Systematic review for seasonal crop diversity influence on the double burden of malnutrition in rural communities
    Veryson Mutandani, Thirukkumar Subramani, Murugasridevi Kalirajan, Sudheesh Manalil
    Frontiers in Sustainable Food Systems, 2025
    This systematic review investigates the influence of seasonal crop diversity on the double burden of malnutrition in rural communities across low-and middle-income countries. The review analyzed n = 22 peer-reviewed studies published in the online databases Scopus, PubMed, Google scholar, and the Food and Agriculture Organization’s sub-websites, HINARI and AGORA, between January 2017 and April 2024. The review used the preferred reporting items for systematic reviews and meta-analyses (PRISMA) 2020 set of guidance to explore how variations in seasonal crop production affect dietary diversity and nutritional outcomes among vulnerable populations. Article quality appraisal using the Effective Public Health Practice Project (EPHPP) tool revealed mixed methodological rigor across eight domains in underpowered studies (n = 18, weak; n = 4, moderate; n = 0, strong), emphasizing the need for caution when interpreting the findings. The findings indicate that increased seasonal crop diversity correlates with improved dietary practices and food security. Yet, challenges of resource access and market constraints hindered these benefits. The systematic review further identified critical gaps in current research and emphasized the need for integrated strategies that promote seasonal crop diversity as a tool to combat malnutrition effectively. The insights gained aimed to inform policy decisions and guide future research efforts focused on enhancing nutrition during conditionally lean seasons.
  • Effect of Germinated Brown Rice Supplementation on Prediabetes Markers: A 120-Day Dietary Intervention Study in Selected Female Groups
    Hemalatha Ganapathyswamy, Thirukkumar Subramani, Kanmani Kalaivanan, Adiyaman Pannerselvam, Amutha Sundararajan
    Rice Science, 2025
  • Development of millet beverage for combating vitamin B12 deficiency in order to achieve food security
    Sheela Punniyamoorthy, Thirukkumar Subramani, Kanchana Shanmugavel, Vellaikumar Sampathrajan, Uma Maheswari Thiyagamoorthy
    Journal of Food Science and Technology, 2025
  • Effect of cottonseed milk on growth performance, hematological and semen characteristics in male Wistar albino rats
    Thirukkumar Subramani, Hemalatha Ganapathyswamy, Vellaikumar Sampathrajan, C. David Raj
    Food Production Processing and Nutrition, 2023
    Various plant based milk extract is appropriate for human nutrition among which cottonseed is one of the potential crops with the advantages of stable milk emulsion, improved nutrient profile with affordable waste utilization. Although cottonseed milk is a popular indigenous beverage, it has not been exploited worldwide for regular consumption owing to the presence of gossypol. The gossypol toxicity and associated gossypol-iron complex formation in the intestine lead to changes in hematological characteristics and alternation of sperm motility in monogastric animals. Male Wistar albino rats weighing 60 to 70 g were divided into four groups of five animals each. The group fed the standard diet (STD) served as control, and the experimental groups included the group (i) rats fed cottonseed diet (CSD) supplemented at 10% of cottonseed level (ii) rats fed conventional aqueous extracted cottonseed milk (CCM) diet (CAD) and (iii) rats fed enzymatic assisted aqueous extracted cottonseed milk (ECM) diet (EAD). The CAD and EAD feed was administrated @ 1 ml/100 g of animal body weight /day for the study period of 45 days among the experimental groups and control group. A significant difference in weight gain of the experimental rats was noticed between the CCM and ECM cottonseed milk extracts fed experimental groups compared with the standard and cottonseed fed groups. The rats fed with CSD, CCM and ECM diet exhibited higher white blood cell counts, also reducing the red blood cells count, hemoglobin hematocrit and platelet in the group compared with STD. No significant difference in semen motility characteristics was noticed among the CSD, CCM and ECM fed groups. In conclusion, the intake of less than the permissible level of gossypol from selected cottonseed and its aqueous extracted milk samples has influenced the hematological parameters and whereas an improved effect was shown in semen characteristics. Graphical Abstract
  • Physico-chemical, structural, and functional properties of protein concentrate from selected pulses: A comparative study
    Sivasankari Ruckmangathan, Hemalatha Ganapathyswamy, Amutha Sundararajan, Umamaheswari Thiyagamoorthy, Rick Green, et al.
    Journal of Food Processing and Preservation, 2022
    The selected pulses viz., chickpea, faba bean, red lentil, and red gram were used for the extraction of protein concentrates using alkaline extraction followed by the isoelectric precipitation. The effect of processing on moisture, protein, lipid, ash, and carbohydrate content of pulse flours and respective protein concentrates (PC) ranged between 5.05% and 13.40%; 17.10% and 84.80%; 1.09% and 5.30%; 2.24% and 3.27%; 3.37 and 60.90%, respectively. The amino acid profile of the pulse protein concentrates (PPC) was on par with that of soybean PC and meets the amino acid requirements of children and adults as per the FAO (Food and Agriculture Organization) specifications. The PC had a smaller particle size (126.70–192.70 nm) than pulse flours (251.90–301.90 nm). Water holding capacity (WHC) and oil holding capacity (OHC) of PC were higher than pulse flours. The solubility of protein concentrates was high at acidic and alkaline pH and low at pH 4.5 (isoelectric pH). The significant reduction in anti‐nutritional factors and better protein digestibility resulted from processing of pulse flours. The processing of pulses into PC will serve as a potential functional food ingredient in various food formulations.Novelty impact statementPulses are processed for the extraction of their fractions and utilized for better food product development. In this research, pulse protein concentrate was extracted from easily available pulses for better utilization and the properties were studied for the development of PPC‐incorporated food products similar to soy protein. In the future, all pulse proteins can be used as alternative proteins for soybean to meet our nutritional requirements in a cheaper manner.
  • Effect of processing on selected pesticide residues in cottonseed (Gossypium spp.)
    Thirukkumar Subramani, Hemalatha Ganapathyswamy, Vellaikumar Sampathrajan, Amutha Sundararajan, Murugan Marimuthu
    Journal of Food Safety, 2022
  • Optimization of extraction parameters to improve cottonseed milk yield and reduce gossypol levels using response surface methodology (RSM)
    Thirukkumar Subramani, Hemalatha Ganapathyswamy, Vellaikumar Sampathrajan, Amutha Sundararajan
    Journal of Food Processing and Preservation, 2022
  • Effect of simple processing on selected pesticide residues in cottonseed (Gossypium spp.)
    Thirukkumar Subramani, Hemalatha Ganapathyswamy, Vellaikumar Sampathrajan, Amutha Sundararajan, Murugan Marimuthu
    Journal of Applied and Natural Science, 2022
  • Influence of enzymes and extraction conditions on high yield of cottonseed milk
    S. Thirukkumar, G. Hemalatha, S. Vellaikumar, M. Murugan, S. Amutha, et al.
    Journal of Environmental Biology, 2021
  • An overview of liposomal nano-encapsulation techniques and its applications in food and nutraceutical
    Thirukkumar Subramani, Hemalatha Ganapathyswamy
    Journal of Food Science and Technology, 2020

RECENT SCHOLAR PUBLICATIONS

  • Effect of optimized germination on nutritional functional and phytochemical characteristics of green gram
    T Subramani, S Ruckmangathan, H Ganapathyswamy, S Palanisamy, ...
    Scientific Reports , 2026
    2026
    Citations: 1
  • Study on various green aqueous extraction techniques for extracting cottonseed milk to improve nutritional quality
    T Subramani, H Ganapathyswamy, V Sampathrajan, UM Thiyagamoorthy
    Journal of Cotton Research 9 (1), 6 , 2026
    2026
  • Deciphering the Significance of Millets as a Superfood in Promoting Gut Health: A Review
    UM Thiyagamoorthy, S Palanisamy, JS Packialakshmi, G Sadayandi, ...
    Food Reviews International, 1-24 , 2025
    2025
    Citations: 1
  • Evaluation of the Nutritional and Therapeutic Potential of Faba Bean Probiotic Yogurt in Ulcerative Colitis-Induced Mouse
    H Ganapathyswamy, U Thiyagamoorthy, S Thirukkumar, H Devagopalan, ...
    Available at SSRN 5603990 , 2025
    2025
  • Systematic review for seasonal crop diversity influence on the double burden of malnutrition in rural communities
    V Mutandani, T Subramani, M Kalirajan, S Manalil
    Frontiers in Sustainable Food Systems 9, 1542711 , 2025
    2025
    Citations: 3
  • Development of millet beverage for combating vitamin B12 deficiency in order to achieve food security
    S Punniyamoorthy, T Subramani, K Shanmugavel, V Sampathrajan, ...
    Journal of Food Science and Technology, 1-11 , 2025
    2025
    Citations: 4
  • Therapeutic and environmental potential of mushrooms in ancient and modern contexts: A review
    P Seethapathy, T Subramani, N Ayrilmis, H Patil
    International Journal of Medicinal Mushrooms 27 (4) , 2025
    2025
    Citations: 5
  • Evaluation of functional, physical and nutritional characteristics of the nutrient‐rich composite bread with wheat, soybean, and moringa flours
    T Subramani, A Sivakumar, J Murugan
    Food Biomacromolecules 1 (2), 35-44 , 2024
    2024
    Citations: 2
  • Effect of Germinated Brown Rice Supplementation on Prediabetes Markers: A 120-Day Dietary Intervention Study in Selected Female Group
    H Ganapathyswamy, T Subramani, K Kanmani, P Adiyaman, ...
    Rice Science, 4 , 2024
    2024
    Citations: 2
  • Assessing the Physicochemical Characteristics: A Comparative Analysis of Various Drying Methods in Osmotic Treated Fruit Slices
    T Subramani, KC Anjusree, S Manalil
    Asian Journal of Dairy and Food Research , 2024
    2024
  • Effect of cottonseed milk on growth performance, hematological and semen characteristics in male Wistar albino rats
    T Subramani, H Ganapathyswamy, V Sampathrajan, C David Raj
    Food Production, Processing and Nutrition 5 (1), 9 , 2023
    2023
    Citations: 1
  • Physico‐chemical, structural, and functional properties of protein concentrate from selected pulses: A comparative study
    S Ruckmangathan, H Ganapathyswamy, A Sundararajan, ...
    Journal of Food Processing and Preservation 46 (12), e17169 , 2022
    2022
    Citations: 27
  • Optimization of extraction parameters to improve cottonseed milk yield and reduce gossypol levels using response surface methodology (RSM)
    T Subramani, H Ganapathyswamy, V Sampathrajan, A Sundararajan
    Journal of Food Processing and Preservation 46 (6), e15945 , 2022
    2022
    Citations: 10
  • Effect of processing on selected pesticide residues in cottonseed (Gossypium spp.)
    T Subramani, H Ganapathyswamy, V Sampathrajan, A Sundararajan, ...
    Journal of Food Safety, e13002 , 2022
    2022
    Citations: 1
  • Influence of enzymes and extraction conditions on high yield of cottonseed milk
    S Thirukkumar, G Hemalatha, S Vellaikumar, M Murugan, S Amutha
    Journal of Environmental Biology 42, 1195-1200 , 2021
    2021
    Citations: 2
  • Studies on selected cotton seed (Gossypium sp) varieties nutrient profile for human consumption in Tamil Nadu
    S THIRUKKUMAR, G HEMALATHA, S VELLAIKUMAR, S AMUTHA, ...
    J. Cotton Res. Dev. 35 (1), 79-87 , 2021
    2021
    Citations: 9
  • Green extract assisted bioactive compounds from fruits and vegetables
    S Thirukkumar, P Vennila, G Hemalatha
    Recent Innovations in Food and Nutritional Sciences 1, 132-149 , 2020
    2020
  • An overview of liposomal nano-encapsulation techniques and its applications in food and nutraceutical
    T Subramani, H Ganapathyswamy
    Journal of Food Science and Technology 57 (10), 3545-3555 , 2020
    2020
    Citations: 237
  • PROCESSING OF BLENDED BEVERAGES AND ITS STORAGE STABILITY
    S Thirukkumar, P Vennila
    Trends & Prospects in Processing of Horticultural Crops, 105-120 , 2019
    2019
    Citations: 7
  • Development of Low Glycemic Gluten Free Bread from Barnyard Millet and Lentil Flour
    G Hemalatha, S Thirukkumar
    International Journal of Nutrition and Food Engineering 12 (6) , 2018
    2018

MOST CITED SCHOLAR PUBLICATIONS

  • An overview of liposomal nano-encapsulation techniques and its applications in food and nutraceutical
    T Subramani, H Ganapathyswamy
    Journal of Food Science and Technology 57 (10), 3545-3555 , 2020
    2020
    Citations: 237
  • Identification of bioactive components in Moringa oleifera fruit by GC-MS
    K Shunmugapriya, P Vennila, S Thirukkumar, M Ilamaran
    J. Pharmacogn. Phytochem 6 (3), 748-751 , 2017
    2017
    Citations: 29
  • Physico‐chemical, structural, and functional properties of protein concentrate from selected pulses: A comparative study
    S Ruckmangathan, H Ganapathyswamy, A Sundararajan, ...
    Journal of Food Processing and Preservation 46 (12), e17169 , 2022
    2022
    Citations: 27
  • Studies on preparation of processed horse gram (Macrotyloma uniflorum) flour incorporated chappathi
    S Thirukkumar, G Sindumathi
    Int J Sci Res 3 (3), 110-111 , 2014
    2014
    Citations: 14
  • Physico-chemical characteristics of noni fruit juice blended squashes during storage
    S Thirukkumar, P Vennila, S Kanchana
    Int. J. Chem. Stud 6 (1), 449-455 , 2018
    2018
    Citations: 13
  • Optimization of extraction parameters to improve cottonseed milk yield and reduce gossypol levels using response surface methodology (RSM)
    T Subramani, H Ganapathyswamy, V Sampathrajan, A Sundararajan
    Journal of Food Processing and Preservation 46 (6), e15945 , 2022
    2022
    Citations: 10
  • Studies on selected cotton seed (Gossypium sp) varieties nutrient profile for human consumption in Tamil Nadu
    S THIRUKKUMAR, G HEMALATHA, S VELLAIKUMAR, S AMUTHA, ...
    J. Cotton Res. Dev. 35 (1), 79-87 , 2021
    2021
    Citations: 9
  • Investigation of total antioxidant activity and phenol in Indian noni fruit (Morinda citrifolia Linn.) juice extraction
    S Thirukkumar, P Vennila, TU Maheswari
    Journal of Pharmacognosy and Phytochemistry 6 (2), 241-243 , 2017
    2017
    Citations: 8
  • PROCESSING OF BLENDED BEVERAGES AND ITS STORAGE STABILITY
    S Thirukkumar, P Vennila
    Trends & Prospects in Processing of Horticultural Crops, 105-120 , 2019
    2019
    Citations: 7
  • Standardization of gluten free chickpea flour based cake mix by using Response Surface Methodology
    S Thirukkumar, G Hemalatha, L Senthamaraiselvi
    International Journal of Current Microbiology and Applied Sciences 8 (6 … , 2017
    2017
    Citations: 7
  • Therapeutic and environmental potential of mushrooms in ancient and modern contexts: A review
    P Seethapathy, T Subramani, N Ayrilmis, H Patil
    International Journal of Medicinal Mushrooms 27 (4) , 2025
    2025
    Citations: 5
  • Studies on Extraction of juice from Noni fruits (Morinda citrifolia Linn.)
    S Thirukkumar, P Vennila, S Kanchana, T Uma Maheswari
    Indian Journal of Natural Sciences 7 (40), 11988-11994 , 2017
    2017
    Citations: 5
  • Development of millet beverage for combating vitamin B12 deficiency in order to achieve food security
    S Punniyamoorthy, T Subramani, K Shanmugavel, V Sampathrajan, ...
    Journal of Food Science and Technology, 1-11 , 2025
    2025
    Citations: 4
  • Effect of utilization of horse gram flour by simple processing methods.
    S Thirukkumar, G Gurumeenakshi
    2015
    Citations: 4
  • Systematic review for seasonal crop diversity influence on the double burden of malnutrition in rural communities
    V Mutandani, T Subramani, M Kalirajan, S Manalil
    Frontiers in Sustainable Food Systems 9, 1542711 , 2025
    2025
    Citations: 3
  • Evaluation of functional, physical and nutritional characteristics of the nutrient‐rich composite bread with wheat, soybean, and moringa flours
    T Subramani, A Sivakumar, J Murugan
    Food Biomacromolecules 1 (2), 35-44 , 2024
    2024
    Citations: 2
  • Effect of Germinated Brown Rice Supplementation on Prediabetes Markers: A 120-Day Dietary Intervention Study in Selected Female Group
    H Ganapathyswamy, T Subramani, K Kanmani, P Adiyaman, ...
    Rice Science, 4 , 2024
    2024
    Citations: 2
  • Influence of enzymes and extraction conditions on high yield of cottonseed milk
    S Thirukkumar, G Hemalatha, S Vellaikumar, M Murugan, S Amutha
    Journal of Environmental Biology 42, 1195-1200 , 2021
    2021
    Citations: 2
  • Effect of optimized germination on nutritional functional and phytochemical characteristics of green gram
    T Subramani, S Ruckmangathan, H Ganapathyswamy, S Palanisamy, ...
    Scientific Reports , 2026
    2026
    Citations: 1
  • Deciphering the Significance of Millets as a Superfood in Promoting Gut Health: A Review
    UM Thiyagamoorthy, S Palanisamy, JS Packialakshmi, G Sadayandi, ...
    Food Reviews International, 1-24 , 2025
    2025
    Citations: 1