TACHITA VLAD-BUBULAC
@icmpp.ro
Scopus Publications
- Advanced polyethersulfone membranes with silver-loaded zeolite for simultaneous heavy metal removal and antibacterial protection
Ioana-Antonia Iftimie, Diana Serbezeanu, Tăchiţă Vlad-Bubulac, Alexandra Bargan, Daniela Rusu, et al.
Colloids and Surfaces A Physicochemical and Engineering Aspects, 2026 - Tailoring thermal, structural, and photocatalytic properties of electrospun poly(ether ether ketone) nanocomposite membranes through TiO2 integration
Diana Serbezeanu, Tachita Vlad-Bubulac, Daniela Rusu, Gabriela Lisa, Lavinia Lupa, et al.
Journal of Environmental Chemical Engineering, 2026 - Study on the Structure, Thermal Properties and Antibacterial Properties of Phosphorus-Modified PVA/TiO2 Composite Films
Alina-Mirela Ipate, Diana Serbezeanu, Ioana-Antonia Iftimie, Gabriela Lisa, Cristina-Mihaela Rîmbu, et al.
Gels, 2025
Phosphorus-modified poly(vinyl alcohol) (PVA) has recently gained increasing attention as a functional polymeric matrix suitable for gel-based systems, owing to its biocompatibility, film-forming ability, and capacity to develop semi-interpenetrating networks. In this work, PVA was chemically modified through the nucleophilic substitution of its hydroxyl groups with the chloride groups of phenyl dichlorophosphate, following a literature-reported method carried out in N,N-dimethylformamide (DMF) as reaction medium, resulting in phosphorus-containing PVA networks (PVA-OP3). Hybrid gel-like films were then prepared by incorporating titanium dioxide nanoparticles (TiO2 NPs), known for their antimicrobial activity, low toxicity, and high stability. The resulting composites were structurally, morphologically, and thermally characterized using FTIR, SEM, and thermogravimetric analysis. The incorporation of TiO2 NPs significantly improved the thermal stability, with T5% increasing from 240 °C for neat PVA-OP3 to 288 °C for the optimal composite, increased the char residue from 4.5% for the neat polymer to 30.1% for PVA-OP3/TiO2-4, and enhanced antimicrobial activity against both Gram-positive and Gram-negative bacteria. These findings demonstrate that PVA-OP3/TiO2 hybrid films possess promising potential as advanced biomaterials for biomedical, protective, and environmental applications. - Multifaceted Nanocomposites Combining Phosphorylated PVA, MXene, and Cholesteric Liquid Crystal: Design and Application Insights
Nanomaterials, 2025 - Dielectric anisotropy in self-assembling MXene-based lyotropic nematic compounds
Marius Andrei Olariu, Tăchiță Vlad-Bubulac, Tudor Alexandru Filip, Ina Turcan
Journal of Physics D Applied Physics, 2024
The formation of a lyotropic liquid crystal phase at the level of MXene-based aqueous dispersions due to the self-assembling capacity of these two-dimensional (2D) materials has been previously successfully reported. However, the influence of electrical external factors has been less studied in spite of the fact that understanding the electrical behaviour of 2D-based liquid crystal compounds is vital for fostering the development of new innovative applications. Consequently, within this paper, we report an in-depth evaluation of the dielectric properties of liquid crystalline phases in Ti3C2 MXene aqueous dispersions. The dependence on the low voltage of planar ε ⊥ ′ to homeotropic ε ∥ ′ orientational transition is emphasized and discussed, while the influence of the electric field frequency at the level of dielectric anisotropy is assessed in respect to various concentrations of MXene flakes within the same 2D-based compounds. Nonetheless, dielectric spectroscopy highlights the biphasic nature (containing both nematic and isotropic phases) of the studied aqueous Ti3C2 MXene inks visible up to 20% MXene. Above this concentration, the existence of a pure nematic phase in the dispersion of highMXene concentration (>20 wt%) was detected based on the evaluation of dielectric permittivity against various voltage values. - Dielectrophoretic direct assembling of Mxene flakes at the level of screen-printed interdigitated microelectrodes and their evaluation in gas sensing applications
Ina Turcan, Tudor Alexandru Filip, Tăchiță Vlad-Bubulac, Daniela Rusu, Marius Andrei Olariu
2d Materials, 2024
Controlling, orientating, and assembling 2D materials is critical for their successful exploitation as active elements in various applications, particularly for sensors. Despite the increased interest in exploiting the properties of MXenes, to date, the direct dielectrophoretic assembly of this category of materials has not been reported. Thus, this work presents an experimental study on dielectrophoretic assembly of pristine MXene flakes at the level of screen-printed interdigitated microelectrodes. The development of MXene uniaxial ‘bridges’ across electrode micro-gaps can be controlled by convenient dielectrophoretic parameters such as voltage and frequency, which are thoroughly discussed. Moreover, appropriate frequencies for avoiding parasitic electrokinetic phenomena (AC electro-osmosis, electrothermal effect) that hamper the application of dielectrophoresis were identified. Finally, the proposed methodology for assembling MXene flakes demonstrates its feasibility of being used for development of chemiresistors as of satisfactory response of pristine MXene ‘bridges’ to ethanol atmosphere. - Differential insights into structural dynamics and photophysical behavior of two phosphorus-containing diesters
Elena Perju, Diana Serbezeanu, Mihaela Homocianu, Mihaela Avadanei, Tăchiţă Vlad-Bubulac
New Journal of Chemistry, 2024
ATR-FTIR spectroscopy was first used as an important and complementary technique to investigate the phase transition of two phosphorus-containing diesters, representing a pioneering study on organophosphorus-based liquid crystals. - Antimicrobial Activity of Artemisia dracunculus Oil-Loaded Agarose/Poly(Vinyl Alcohol) Hydrogel for Bio-Applications
Cristina Mihaela Rîmbu, Diana Serbezeanu, Tăchiță Vlad-Bubulac, Dana Mihaela Suflet, Iuliana Motrescu, et al.
Gels, 2024
In this study, the potential use of Artemisia dracunculus essential oil in bio-applications was investigated. Firstly, the phytochemicals from Artemisia dracunculus were analyzed by different methods. Secondly, the Artemisia dracunculus essential oil was incorporated into the hydrogel matrix based on poly(vinyl alcohol) (PVA) and agar (A). The structural, morphological, and physical properties of the hydrogel matrix loaded with different amounts of Artemisia dracunculus essential oil were thoroughly investigated. FTIR analysis revealed the successful loading of the essential oil Artemisia dracunculus into the PVA/A hydrogel matrix. The influence of the mechanical properties and antimicrobial activity of the PVA/A hydrogel matrix loaded with different amounts of Artemisia dracunculus was also assessed. The antimicrobial activity of Artemisia dracunculus (EO Artemisia dracunculus) essential oil was tested using the disk diffusion method and the time-kill assay method after entrapment in the PVA/A hydrogel matrices. The results showed that PVA/agar-based hydrogels loaded with EO Artemisia dracunculus exhibited significant antimicrobial activity (log reduction ratio in the range of 85.5111–100%) against nine pathogenic isolates, both Gram-positive (S. aureus, MRSA, E. faecalis, L. monocytogenes) and Gram-negative (E. coli, K. pneumoniae, S. enteritidis, S. typhimurium, and A. salmonicida). The resulted biocompatible polymers proved to have enhanced properties when functionalized with the essential oil of Artemisia dracunculus, offering opportunities and possibilities for novel applications. - Evaluation of Poly(vinyl alcohol)–Xanthan Gum Hydrogels Loaded with Neomycin Sulfate as Systems for Drug Delivery
Diana Serbezeanu, Manuela Maria Iftime, Gabriela-Liliana Ailiesei, Alina-Mirela Ipate, Alexandra Bargan, et al.
Gels, 2023
In recent years, multidrug-resistant bacteria have developed the ability to resist multiple antibiotics, limiting the available options for effective treatment. Raising awareness and providing education on the appropriate use of antibiotics, as well as improving infection control measures in healthcare facilities, are crucial steps to address the healthcare crisis. Further, innovative approaches must be adopted to develop novel drug delivery systems using polymeric matrices as carriers and support to efficiently combat such multidrug-resistant bacteria and thus promote wound healing. In this context, the current work describes the use of two biocompatible and non-toxic polymers, poly(vinyl alcohol) (PVA) and xanthan gum (XG), to achieve hydrogel networks through cross-linking by oxalic acid following the freezing/thawing procedure. PVA/XG-80/20 hydrogels were loaded with different quantities of neomycin sulfate to create promising low-class topical antibacterial formulations with enhanced antimicrobial effects. The inclusion of neomycin sulfate in the hydrogels is intended to impart them with powerful antimicrobial properties, thereby facilitating the development of exceptionally efficient topical antibacterial formulations. Thus, incorporating higher quantities of neomycin sulfate in the PVA/XG-80/20-2 and PVA/XG-80/20-3 formulations yielded promising cycling characteristics. These formulations exhibited outstanding removal efficiency, exceeding 80% even after five cycles, indicating remarkable and consistent adsorption performance with repeated use. Furthermore, both PVA/XG-80/20-2 and PVA/XG-80/20-3 formulations outperformed the drug-free sample, PVA/XG-80/20, demonstrating a significant enhancement in maximum compressive stress. - Simultaneous Enhancement of Flame Resistance and Antimicrobial Activity in Epoxy Nanocomposites Containing Phosphorus and Silver-Based Additives
Tăchiță Vlad-Bubulac, Corneliu Hamciuc, Diana Serbezeanu, Ana-Maria Macsim, Gabriela Lisa, et al.
Molecules, 2023
The design and manufacture of innovative multifunctional materials possessing superior characteristics, quality and standards, rigorously required for future development of existing or emerging advanced technologies, is of great importance. These materials should have a very low degree of influence (or none) on the environmental and human health. Adjusting the properties of epoxy resins with organophosphorus compounds and silver-containing additives is key to the simultaneous improvement of the flame-resistant and antimicrobial properties of advanced epoxy-based materials. These environmentally friendly epoxy resin nanocomposites were manufactured using two additives, a reactive phosphorus-containing bisphenol derived from vanillin, namely, (4-(((4-hidroxyphenyl)amino)(6-oxido-6H-dibenzo[c,e][1,2]oxaphosphinin-6-yl)methyl)-2-methoxyphenyl) phenylphosphonate (BPH), designed as both cross-linking agent and a flame-retardant additive for epoxy resin; and additional silver-loaded zeolite L nanoparticles (Ze–Ag NPs) used as a doping additive to impart antimicrobial activity. The effect of BPH and Ze–Ag NPs content on the structural, morphological, thermal, flame resistance and antimicrobial characteristics of thermosetting epoxy nanocomposites was investigated. The structure and morphology of epoxy nanocomposites were investigated via FTIR spectroscopy and scanning electron microscopy (SEM). In general, the nanocomposites had a glassy and homogeneous morphology. The samples showed a single glass transition temperature in the range of 166–194 °C and an initiation decomposition temperature in the range of 332–399 °C. The introduction of Ze–Ag NPs in a concentration of 7–15 wt% provided antimicrobial activity to epoxy thermosets. - Flame-Resistant Poly(vinyl alcohol) Composites with Improved Ionic Conductivity
Diana Serbezeanu, Corneliu Hamciuc, Tăchiță Vlad-Bubulac, Alina-Mirela Ipate, Gabriela Lisa, et al.
Membranes, 2023 - Organophosphorus Reinforced Poly(vinyl alcohol) Nanocomposites Doped with Silver-Loaded Zeolite L Nanoparticles as Sustainable Materials for Packaging Applications
Tăchiță Vlad-Bubulac, Corneliu Hamciuc, Diana Serbezeanu, Dana Mihaela Suflet, Daniela Rusu, et al.
Polymers, 2023 - Design and Synthesis of Amphiphilic Graft Polyphosphazene Micelles for Docetaxel Delivery
Diana Serbezeanu, Tǎchițǎ Vlad-Bubulac, Ana-Maria Macsim, Vera Bǎlan
Pharmaceutics, 2023 - Evaluation of the Antibacterial Properties of Polyvinyl Alcohol-Pullulan Scaffolds Loaded with Nepeta racemosa Lam. Essential Oil and Perspectives for Possible Applications
Constantin Lungoci, Cristina Mihaela Rîmbu, Iuliana Motrescu, Diana Serbezeanu, Cristina Elena Horhogea, et al.
Plants, 2023 - Eco-friendly flame retardant epoxy nanocomposites based on polyphosphonate and halloysite nanotubes
Corneliu Hamciuc, Tăchiță Vlad‐Bubulac, Diana Serbezeanu, Gabriela Lisa, Ion Anghel, et al.
Journal of Vinyl and Additive Technology, 2023 - Electrospun Nanofibers Based on Polymer Blends with Tunable High-Performance Properties for Innovative Fire-Resistant Materials
Diana Serbezeanu, Corneliu Hamciuc, Tăchiță Vlad-Bubulac, Mihaela-Dorina Onofrei, Alexandra Bargan, et al.
Polymers, 2022 - Optical and Flame-Retardant Properties of a Series of Polyimides Containing Side Chained Bulky Phosphaphenanthrene Units
Mihaela Homocianu, Diana Serbezeanu, Gabriela Lisa, Mihai Brebu, Tăchiță Vlad-Bubulac
International Journal of Molecular Sciences, 2022 - Thermal Properties and Flammability Characteristics of a Series of DGEBA-Based Thermosets Loaded with a Novel Bisphenol Containing DOPO and Phenylphosphonate Units
Corneliu Hamciuc, Tăchiță Vlad-Bubulac, Diana Serbezeanu, Ana-Maria Macsim, Gabriela Lisa, et al.
Materials, 2022 - Tailoring Thermal and Electrical Properties of Jeffamine Segmented Polyetherimide Composite Films Containing BaTiO3 particles
Corneliu Hamciuc, Gabriela Lisa, Diana Serbezeanu, Luiza Mădălina Grădinaru, Mihai Asăndulesa, et al.
Polymers, 2022 - Effects of Phosphorus and Boron Compounds on Thermal Stability and Flame Retardancy Properties of Epoxy Composites
Corneliu Hamciuc, Tăchiță Vlad-Bubulac, Diana Serbezeanu, Ana-Maria Macsim, Gabriela Lisa, et al.
Polymers, 2022 - Electrospun Copoly(ether imide) Nanofibers Doped with Silver-Loaded Zeolite as Materials for Biomedical Applications
Corneliu Hamciuc, Tăchiţă Vlad-Bubulac, Maria Bercea, Dana Mihaela Suflet, Florica Doroftei, et al.
ACS Applied Polymer Materials, 2022 - Fabrication of Poly(vinyl alcohol)/Chitosan Composite Films Strengthened with Titanium Dioxide and Polyphosphonate Additives for Packaging Applications
Tăchiță Vlad-Bubulac, Corneliu Hamciuc, Cristina Mihaela Rîmbu, Magdalena Aflori, Maria Butnaru, et al.
Gels, 2022 - Phosphorylated Poly(vinyl alcohol) Electrospun Mats for Protective Equipment Applications
Diana Serbezeanu, Tăchiță Vlad-Bubulac, Mihaela Dorina Onofrei, Florica Doroftei, Corneliu Hamciuc, et al.
Nanomaterials, 2022 - Development of histamine reinforced poly(vinyl alcohol)/chitosan blended films for potential biomedical applications
Diana Serbezeanu, Maria Bercea, Maria Butnaru, Alexandru Alin Enache, Cristina Mihaela Rîmbu, et al.
Journal of Applied Polymer Science, 2022 - Tunable Properties via Composition Modulations of Poly(vinyl alcohol)/Xanthan Gum/Oxalic Acid Hydrogels
Alin Alexandru Enache, Diana Serbezeanu, Tăchiță Vlad-Bubulac, Alina-Mirela Ipate, Dana Mihaela Suflet, et al.
Materials, 2022
