Victor R. Lazar

@srmist.edu.in

Assistant Professor, Medicine & Health Sciences
Medicine & Health Sciences
SRM Institute of Science and Technology

Victor R. Lazar


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https://researchid.co/victorlazar

EDUCATION

PhD Radiology
M.Sc. Medical Imaging
B.Sc. Radiology and Imaging Technology

RESEARCH, TEACHING, or OTHER INTERESTS

Radiology, Nuclear Medicine and imaging, Orthopedics and Sports Medicine, Dentistry
6

Scopus Publications

107

Scholar Citations

4

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Automated deep learning pipeline for measuring lumbar thecal sac AP diameter on mid-sagittal MR images
    Akash Nixon, Victor Rakesh Lazar, Saikiran Pendem, Karan Sekar, Senthil Kumar Aiyappan, Sundara Raja Perumal
    BMC Medical Imaging, 2026
    OBJECTIVE: To develop and validate an automated, disc-level deep learning pipeline for quantitative measurement of anteroposterior (AP) thecal sac diameter on mid-sagittal lumbar T2-weighted MRI. MATERIALS AND METHODS: In this retrospective study, 511 mid-sagittal lumbar T2 MRI examinations were included after screening 758 cases and applying predefined exclusions. The workflow combined YOLOv8 oriented bounding boxes (OBB) for disc-level localization and orientation estimation, homography-based ROI warping, Attention U-Net segmentation, and skeleton-based AP diameter computation in millimeters using DICOM pixel spacing. Validation was performed on internal (50) and external (50; RSNA 2024 lumbar dataset) cohorts with two radiologists providing the reference standard. RESULT: Inter-reader agreement was excellent (ICC (2, 1) = 0.967; 711 paired measurements). Against the reader-mean reference, the pipeline achieved an overall MAE of 0.994 mm (711 disc-level measurements). Internal validation showed MAE 0.909 mm (357 measurements) and external validation MAE 1.079 mm (354 measurements). Severity-wise MAE remained ~ 1 mm (mild 0.930 mm; moderate 1.234 mm; severe 1.038 mm). Automatic disc-level labeling was performed, and OBB-derived orientation significantly improved AP measurement-line validity versus axis-aligned detection (acceptable lines 99.02% vs. 77.64%). CONCLUSION: An orientation-aware YOLOv8-OBB + Attention U-Net pipeline enables automated, disc-level AP thecal sac diameter quantification on mid-sagittal lumbar MRI with ~ 1 mm error relative to expert reference, supporting standardized morphometric reporting and measurement-driven assessment of lumbar stenosis.
  • Europium-doped cerium oxide nanoparticle-impregnated Hyalgan® (CartiOxgel): an intra-articular contrast agent for X-ray CT and optical imaging
    Hema Brindha Masanam, Sina Jafari, Ashwin Kumar Narasimhan, Priyatha Premanth, Margaret Salomi, Victor R. Lazar, Sentil Kumar Aiyappan, Sruthi Ann Alex
    Rsc Advances, 2025
    CartiOxgel, a hybrid nano-contrast agent (EuC NPs in Hyalgan®), shows superior contrast and visibility in live X-ray CT imaging of Wistar rat knees post intra-articular injection, compared to commercial Omnipaque™ iodine.
  • Post Contrast-Acute Kidney Injury in CT Imaging: A Knowledge, Perception and Practice Assessment among Radiographers and Radiologists
    Punitha Pavadai, Victor Rakesh Lazar, Kirthi Sathyakumar, Senthil Kumar Aiyappan, Preethi Baskar, et al.
    Giornale Italiano Di Nefrologia, 2025
    This research highlights the important roles of radiologists and radiographers in managing and preventing PC-AKI. There are significant knowledge gaps, particularly in emergency situations and when dealing with pregnant or paediatric patients. Radiographers, in particular, demonstrate a lack of understanding regarding PC-AKI prevention, indicating a need for specialized training.
  • Generative Pre-trained Transformer: Trends, Applications, Strengths and Challenges in Dentistry: A Systematic Review
    Sibyl Siluvai, Vivek Narayanan, Vinoo Subramaniam Ramachandran, Victor Rakesh Lazar
    Healthcare Informatics Research, 2025
    Objectives: The integration of large language models (LLMs), particularly those based on the generative pre-trained transformer (GPT) architecture, has begun to revolutionize various fields, including dentistry. Despite these promising applications, the use of GPT in dentistry presents several challenges. Ongoing research and the development of robust ethical frameworks are essential to mitigate these issues and enhance the responsible deployment of GPT technologies in clinical settings. Hence, this systematic review aims to explore the trends, applications, strengths, and challenges associated with the use of GPT in dentistry.Methods: Articles were selected if they contained detailed information on the application of GPT in dentistry. The search strategy used in systematic reviews follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Our search of databases and other sources yielded a total of 704 studies. After removing duplicates and conducting a full-text screening, 16 articles were included in the review. The methodological quality of the research was evaluated using the Critical Appraisal Skills Programme (CASP) checklist.Results: Out of a total of 91 articles published on GPT in dentistry, 20 were editorials and 11 were narrative reviews; these were excluded, leaving 60 original research articles for further analysis. The articles were assessed based on the type of results they provided. Ultimately, 16 articles that reported positive findings with robust methodology were included in this reviewConclusions: The results highlight mixed responses; therefore, further research on integration into clinical workflows must be conducted with extensive methodological rigor.
  • Nutritional Status, Prevalence of Early Childhood Caries, and its Association among Preschool Children in Northeast India
    Nandita Kshetrimayum, Sibyl Siluvai, Prabhat Kumar Chaudhuri, Talisunup Longkumar, Darshana Bennadi, Victor Rakesh Lazar
    Contemporary Clinical Dentistry, 2023
    Background: Early childhood caries (ECC) is a common public health problem in developing countries. Children with severe decay can also have altered eating habits and preferences. Therefore, ECC can influence nutritional health. Aim: The aim is to find the prevalence of ECC and nutritional status and to evaluate its association among preschool children in Northeast India. Study Design and Data Collection Methods: This descriptive cross-sectional study was conducted among 384 preschool children aged 2–6 years. The sampling unit comprised the children attending the pediatric dentistry department of one dental college. Information regarding sociodemographic factors, child feeding habits, and child oral hygiene practices was obtained from the parents using a pretested questionnaire. Weight and height were evaluated to assess the nutritional status. The decay, missing, filled teeth index for primary teeth was used to determine the dental caries status. Results: The mean value of carious teeth for 384 children aged 2–6 years was 5.6 ± 2.43. Most kids who had caries (74.7%) belonged to the moderate category (dmft >7), followed by the low sort, which was 16.7%, and then by those in the higher class (8.6%). The body mass index (BMI) for age revealed that 5.2% were overweight, 15.1% were thin, and 8.3% were obese. Most of those with high caries (i.e., dmft >7) were underweight or in the normal weight category. Pearson correlation showed no significant correlation between ECC with BMI-for-age (r = 0.04, P > 0.05). Conclusion: The prevalence of dental caries among children below the age of 5 years in Imphal was high. The risk factors for ECC included age, low maternal education, improper feeding, and oral hygiene habits. However, the results revealed no significant relationship between ECC and BMI.
  • The high bone mass phenotype is characterised by a combined cortical and trabecular bone phenotype: Findings from a pQCT case-control study
    Celia L. Gregson, Adrian Sayers, Victor Lazar, Sue Steel, Elaine M. Dennison, Cyrus Cooper, George Davey Smith, Jörn Rittweger, Jon H. Tobias
    Bone, 2013
    High bone mass (HBM), detected in 0.2% of DXA scans, is characterised by a mild skeletal dysplasia largely unexplained by known genetic mutations. We conducted the first systematic assessment of the skeletal phenotype in unexplained HBM using pQCT in our unique HBM population identified from screening routine UK NHS DXA scans. pQCT measurements from the mid and distal tibia and radius in 98 HBM cases were compared with (i) 65 family controls (constituting unaffected relatives and spouses), and (ii) 692 general population controls. HBM cases had substantially greater trabecular density at the distal tibia (340 [320, 359] mg/cm(3)), compared to both family (294 [276, 312]) and population controls (290 [281, 299]) (p<0.001 for both, adjusted for age, gender, weight, height, alcohol, smoking, malignancy, menopause, steroid and estrogen replacement use). Similar results were obtained at the distal radius. Greater cortical bone mineral density (cBMD) was observed in HBM cases, both at the midtibia and radius (adjusted p<0.001). Total bone area (TBA) was higher in HBM cases, at the distal and mid tibia and radius (adjusted p<0.05 versus family controls), suggesting greater periosteal apposition. Cortical thickness was increased at the mid tibia and radius (adjusted p<0.001), implying reduced endosteal expansion. Together, these changes resulted in greater predicted cortical strength (strength strain index [SSI]) in both tibia and radius (p<0.001). We then examined relationships with age; tibial cBMD remained constant with increasing age amongst HBM cases (adjusted β -0.01 [-0.02, 0.01], p=0.41), but declined in family controls (-0.05 [-0.03, -0.07], p<0.001) interaction p=0.002; age-related changes in tibial trabecular BMD, CBA and SSI were also divergent. In contrast, at the radius HBM cases and controls showed parallel age-related declines in cBMD and trabecular BMD. HBM is characterised by increased trabecular BMD and by alterations in cortical bone density and structure, leading to substantial increments in predicted cortical bone strength. In contrast to the radius, neither trabecular nor cortical BMD declined with age in the tibia of HBM cases, suggesting attenuation of age-related bone loss in weight-bearing limbs contributes to the observed bone phenotype.

RECENT SCHOLAR PUBLICATIONS

  • Awareness, Perceptions and Preferences of Various Teaching and Learning Methodologies Among Medical Imaging Technology Students in Chennai
    S Hari, K Sekar, VR Lazar, A Nixon, S Siluvai, EV Kumar, SK Aiyappan
    2026.0
  • Automated deep learning pipeline for measuring lumbar thecal sac AP diameter on mid-sagittal MR images
    A Nixon, VR Lazar, S Pendem, K Sekar, SK Aiyappan, SR Perumal
    BMC Medical Imaging , 2026
    2026.0
  • Post Contrast-Acute Kidney Injury in CT Imaging: A Knowledge, Perception and Practice Assessment among Radiographers and Radiologists
    P Pavadai, VR Lazar, K Sathyakumar, SK Aiyappan, P Baskar, ...
    Giornale italiano di nefrologia: organo ufficiale della Societa italiana di … , 2025
    2025.0
  • Generative pre-trained transformer: Trends, applications, strengths and challenges in dentistry: A systematic review
    S Siluvai, V Narayanan, VS Ramachandran, VR Lazar
    Healthcare Informatics Research 31 (2), 189-199 , 2025
    2025.0
    Citations: 5
  • Europium-doped cerium oxide nanoparticle-impregnated Hyalgan®(CartiOxgel): an intra-articular contrast agent for X-ray CT and optical imaging
    HB Masanam, S Jafari, AK Narasimhan, P Premanth, M Salomi, VR Lazar, ...
    RSC advances 15 (29), 23374-23395 , 2025
    2025.0
    Citations: 4
  • Salivary Duct Cyst: A Rare Case Report
    D Vinayachandran, SK Balasubramanian, S Siluvai, VR Lazar, ...
    Achievements and Challenges of Medicine and Medical Science Vol. 2, 1-14 , 2024
    2024.0
  • Navigating Barriers to Oral Health Challenges Faced by Children With Autism Spectrum Disorder: A Scoping Review
    J Alexander, S Siluvai, AM George, I KP, VR Lazar, N Kshetrimayum
    Cureus 16 (8) , 2024
    2024.0
    Citations: 7
  • Nutritional Status, Prevalence of Early Childhood Caries, and its Association among Preschool Children in Northeast India
    N Kshetrimayum, S Siluvai, PK Chaudhuri, T Longkumar, D Bennadi, ...
    Contemporary Clinical Dentistry 14 (4), 300-306 , 2023
    2023.0
    Citations: 1
  • Automated Deep Learning Pipeline for Measuring Lumbar Thecal Sac AP
    A Nixon¹, VR Lazar, S Pendem, K Sekar⁴, SK Aiyappan⁵, SR Perumal⁶
    Remote Sensing, 60 , 2022
    2022.0
  • Commissioning of a new wide-bore MRI scanner for radiotherapy planning of head and neck cancer
    GP Liney, SC Owen, AKE Beaumont, VR Lazar, DJ Manton, AW Beavis
    The British Journal of Radiology 86 (1027), 20130150 , 2013
    2013.0
    Citations: 52
  • The high bone mass phenotype is characterised by a combined cortical and trabecular bone phenotype: Findings from a pQCT case–control study
    CL Gregson, A Sayers, V Lazar, S Steel, EM Dennison, C Cooper, ...
    Bone 52 (1), 380-388 , 2013
    2013.0
    Citations: 34
  • PD-0326 COMMISSIONING OF A NEW WIDE BORE MRI SCANNER FOR RADIOTHERAPY PLANNING OF HEAD & NECK CANCER
    SC Owen, GP Liney, AKE Beaumont, DJ Manton, VR Lazar, AW Beavis
    Radiotherapy and Oncology 103, S129-S130 , 2012
    2012.0
  • THE UNIVERSITY OF HULL
    VR Lazar
    2011.0
  • The high bone mass phenotype is characterised by increased subcutaneous and intra-muscular fat, but decreased marrow fat
    C Gregson, A Sayers, S Steel, V Lazar, J Rittweger, J Tobias
    Front. Endocrinol. Conference Abstract: 2011 joint meeting of the Bone … , 2011
    2011.0
  • Quantification using Textural Analysis on MR Bone Data
    VR Lazar, GP Liney, DJ Manton, P Gibbs, C Gregson, S Steel, J Rittweger, ...
    Proc. Intl. Soc. Mag. Reson. Med 19, 3235 , 2011
    2011.0
  • Quantification of bone using a 3.0 tesla clinical magnetic resonance scanner
    VR Lazar
    University of Hull , 2011
    2011.0
    Citations: 2
  • Software tools for MR and pQCT bone quantification
    VR Lazar, GP Liney, DJ Manton, P Gibbs, M Lowry, CL Gregson, ...
    Proceedings of the ISMRM-ESMRMB Joint Annual Meeting , 2010
    2010.0
    Citations: 1
  • Preliminary in-vivo bone quantification results using MR and pQCT
    VR Lazar, GP Liney, DJ Manton, P Gibbs, M Lowry, CL Gregson, ...
    Proc. Intl. Soc. Mag. Reson. Med 18, 784 , 2010
    2010.0
  • Anomalous lipid signal investigation when measuring water/lipid signal with unsuppressed< 1> H MR spectroscopy
    VR Lazar, DJ Manton, T Schirmer, R Noeske, GP Liney, M Lowry, M Lorch, ...
    ISMRM-ESMRMB Joint Annual Meeting 2010 , 2010
    2010.0
    Citations: 1
  • INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
    C Esther, VR Lazar

MOST CITED SCHOLAR PUBLICATIONS

  • Commissioning of a new wide-bore MRI scanner for radiotherapy planning of head and neck cancer
    GP Liney, SC Owen, AKE Beaumont, VR Lazar, DJ Manton, AW Beavis
    The British Journal of Radiology 86 (1027), 20130150 , 2013
    2013.0
    Citations: 52
  • The high bone mass phenotype is characterised by a combined cortical and trabecular bone phenotype: Findings from a pQCT case–control study
    CL Gregson, A Sayers, V Lazar, S Steel, EM Dennison, C Cooper, ...
    Bone 52 (1), 380-388 , 2013
    2013.0
    Citations: 34
  • Navigating Barriers to Oral Health Challenges Faced by Children With Autism Spectrum Disorder: A Scoping Review
    J Alexander, S Siluvai, AM George, I KP, VR Lazar, N Kshetrimayum
    Cureus 16 (8) , 2024
    2024.0
    Citations: 7
  • Generative pre-trained transformer: Trends, applications, strengths and challenges in dentistry: A systematic review
    S Siluvai, V Narayanan, VS Ramachandran, VR Lazar
    Healthcare Informatics Research 31 (2), 189-199 , 2025
    2025.0
    Citations: 5
  • Europium-doped cerium oxide nanoparticle-impregnated Hyalgan®(CartiOxgel): an intra-articular contrast agent for X-ray CT and optical imaging
    HB Masanam, S Jafari, AK Narasimhan, P Premanth, M Salomi, VR Lazar, ...
    RSC advances 15 (29), 23374-23395 , 2025
    2025.0
    Citations: 4
  • Quantification of bone using a 3.0 tesla clinical magnetic resonance scanner
    VR Lazar
    University of Hull , 2011
    2011.0
    Citations: 2
  • Nutritional Status, Prevalence of Early Childhood Caries, and its Association among Preschool Children in Northeast India
    N Kshetrimayum, S Siluvai, PK Chaudhuri, T Longkumar, D Bennadi, ...
    Contemporary Clinical Dentistry 14 (4), 300-306 , 2023
    2023.0
    Citations: 1
  • Software tools for MR and pQCT bone quantification
    VR Lazar, GP Liney, DJ Manton, P Gibbs, M Lowry, CL Gregson, ...
    Proceedings of the ISMRM-ESMRMB Joint Annual Meeting , 2010
    2010.0
    Citations: 1
  • Anomalous lipid signal investigation when measuring water/lipid signal with unsuppressed< 1> H MR spectroscopy
    VR Lazar, DJ Manton, T Schirmer, R Noeske, GP Liney, M Lowry, M Lorch, ...
    ISMRM-ESMRMB Joint Annual Meeting 2010 , 2010
    2010.0
    Citations: 1
  • Awareness, Perceptions and Preferences of Various Teaching and Learning Methodologies Among Medical Imaging Technology Students in Chennai
    S Hari, K Sekar, VR Lazar, A Nixon, S Siluvai, EV Kumar, SK Aiyappan
    2026.0
  • Automated deep learning pipeline for measuring lumbar thecal sac AP diameter on mid-sagittal MR images
    A Nixon, VR Lazar, S Pendem, K Sekar, SK Aiyappan, SR Perumal
    BMC Medical Imaging , 2026
    2026.0
  • Post Contrast-Acute Kidney Injury in CT Imaging: A Knowledge, Perception and Practice Assessment among Radiographers and Radiologists
    P Pavadai, VR Lazar, K Sathyakumar, SK Aiyappan, P Baskar, ...
    Giornale italiano di nefrologia: organo ufficiale della Societa italiana di … , 2025
    2025.0
  • Salivary Duct Cyst: A Rare Case Report
    D Vinayachandran, SK Balasubramanian, S Siluvai, VR Lazar, ...
    Achievements and Challenges of Medicine and Medical Science Vol. 2, 1-14 , 2024
    2024.0
  • Automated Deep Learning Pipeline for Measuring Lumbar Thecal Sac AP
    A Nixon¹, VR Lazar, S Pendem, K Sekar⁴, SK Aiyappan⁵, SR Perumal⁶
    Remote Sensing, 60 , 2022
    2022.0
  • PD-0326 COMMISSIONING OF A NEW WIDE BORE MRI SCANNER FOR RADIOTHERAPY PLANNING OF HEAD & NECK CANCER
    SC Owen, GP Liney, AKE Beaumont, DJ Manton, VR Lazar, AW Beavis
    Radiotherapy and Oncology 103, S129-S130 , 2012
    2012.0
  • THE UNIVERSITY OF HULL
    VR Lazar
    2011.0
  • The high bone mass phenotype is characterised by increased subcutaneous and intra-muscular fat, but decreased marrow fat
    C Gregson, A Sayers, S Steel, V Lazar, J Rittweger, J Tobias
    Front. Endocrinol. Conference Abstract: 2011 joint meeting of the Bone … , 2011
    2011.0
  • Quantification using Textural Analysis on MR Bone Data
    VR Lazar, GP Liney, DJ Manton, P Gibbs, C Gregson, S Steel, J Rittweger, ...
    Proc. Intl. Soc. Mag. Reson. Med 19, 3235 , 2011
    2011.0
  • Preliminary in-vivo bone quantification results using MR and pQCT
    VR Lazar, GP Liney, DJ Manton, P Gibbs, M Lowry, CL Gregson, ...
    Proc. Intl. Soc. Mag. Reson. Med 18, 784 , 2010
    2010.0
  • INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
    C Esther, VR Lazar