Vijayachitra Modhukur

@ut.ee

Researcher, Faculty of Medicine, Institute of Clinical Medicine
University of Tartu

RESEARCH INTERESTS

Bioinformatics, Reproduction, Cancer biology
1689

Scholar Citations

14

Scholar h-index

17

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Aberrant epithelial differentiation may contribute to endometrial polyp formation: insights from single-cell analysis
    ADS Pathare, A Lawarde, K Täär, SV Moreno, A Apostolov, V Modhukur, ...
    Systems Biology in Reproductive Medicine 72 (1), 131-148 , 2026
    2026
  • EMMA-STRAT: A Multi-Omics Based Machine Learning Framework for Stratification of Endometrial Carcinoma Molecular Subtypes and MSI Status
    N Patel, A Salumets, V Modhukur
    2026
  • Peer Support in Online Discussions of Male Infertility: A Natural Language Processing Study of Reddit
    M Khatun, N Patel, M Loid, A Destouni, P Lingasamy, S Lulu S, M Peters, ...
    medRxiv, 2026.03. 09.26347980 , 2026
    2026
  • VEGF-D and VEGF-C as Biomarkers in Endometrial Cancer: Association with Tumor Grade, Stage and Lymphovascular Invasion
    O Khoptiana, O Mushii, M Karasek, V Adhikary, V Modhukur, M Bobinski, ...
    2026
  • Temporal evolution of digital health communication in Rheumatoid Arthritis: A longitudinal NLP analysis of reddit discussions (2018–2024)
    N Patel, R Sharma, P Lingasamy, V Sundararajan, SL S, V Modhukur
    PLoS One 21 (1), e0341006 , 2026
    2026
    Citations: 1
  • Understanding user perceptions of DeepSeek: insights from sentiment, topic and network analysis using a Reddit-based study
    N Patel, R Sharma, P Lingasamy, V Sundararajan, S Lulu Sudhakaran, ...
    Frontiers in Artificial Intelligence 8, 1703949 , 2026
    2026
    Citations: 1
  • Serum-MiR-CanPred: deep learning framework for pan-cancer classification and miRNA-targeted drug discovery
    N Patel, A Lawarde, SM Surisetti, P Thiruselvam, P Lingasamy, ...
    RNA biology 22 (1), 1-19 , 2025
    2025
    Citations: 2
  • Explainable machine learning for preoperative relapse prediction in molecularly stratified endometrial cancer: A single-center finnish cohort study
    SV Moreno, M Khatun, A Pasanen, R Bützow, A Salumets, M Loukovaara, ...
    Computational and Structural Biotechnology Journal , 2025
    2025
  • Corrigendum to “OncoProExp: An interactive shiny web application for comprehensive cancer proteomics and phosphoproteomics analysis”[Comput. Struct. Biotechnol. J. 27 (2025 …
    ES Rahmani, P Lingasamy, S Khojand, A Lawarde, SV Moreno, ...
    2025
  • OncoProExp: An interactive shiny web application for comprehensive cancer proteomics and phosphoproteomics analysis
    ES Rahmani, P Lingasamy, S Khojand, A Lawarde, SV Moreno, ...
    Computational and structural biotechnology journal , 2025
    2025
    Citations: 3
  • Aberrant epithelialization: A plausible factor for the development of endometrial polyps
    ADS Pathare, A Lawarde, K Täär, SV Moreno, A Apostolov, V Modhukur, ...
    bioRxiv, 2025.08. 18.670791 , 2025
    2025
  • Correction: Artificial intelligence in cancer epigenomics
    K Sahoo, P Lingasamy, SL Sudhakaran, A Salumets, V Sundararajan, ...
    2025
  • Proteome changes associated with effect of high dose single-fractionation radiation on lung adenocarcinoma cell lines
    E Leis, V Modhukur, H Lust, M Vardja, M Saarma, I Ilves, M Pütsepp, ...
    Scientific Reports 15 (1), 24245 , 2025
    2025
    Citations: 1
  • Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine
    K Sahoo, P Lingasamy, M Khatun, SL Sudhakaran, A Salumets, ...
    Epigenetics & chromatin 18 (1), 35 , 2025
    2025
    Citations: 45
  • Tumor Tissue-of-Origin Classification Using miRNA-mRNA-lncRNA Interaction Networks and Machine Learning Methods
    A Lawarde, M Khatun, P Lingasamy, A Salumets, V Modhukur
    Frontiers in Bioinformatics 5, 1-29 , 2025
    2025
    Citations: 6
  • OncoProExp: An Interactive Shiny Web Application for Comprehensive Cancer Proteomics and Phosphoproteomics Analysis
    P Lingasamy, S Khojand, A Lawarde, S Vela Moreno, A Salumets, ...
    2025
  • OncoProExp: An Interactive Shiny Web Application for Comprehensive Cancer Proteomics and Phosphoproteomics Analysis
    E Sharif Rahmani, P Lingasamy, S Khojand, A Lawarde, S Vela Moreno, ...
    bioRxiv, 2025.03. 06.641407 , 2025
    2025
  • Hypoxic conditions affect transcriptome of endometrial stromal cells in endometriosis and promote TGFBI axis
    M Sarsenova, NR Boggavarapu, K Kask, V Modhukur, K Samuel, H Karro, ...
    Frontiers in Endocrinology 15, 1465393 , 2024
    2024
    Citations: 4
  • Stanniocalcin protein expression in female reproductive organs: literature review and public cancer database analysis
    M Khatun, V Modhukur, TT Piltonen, JS Tapanainen, A Salumets
    Endocrinology 165 (10), bqae110 , 2024
    2024
    Citations: 5
  • Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level
    M Sarsenova, A Lawarde, ADS Pathare, M Saare, V Modhukur, ...
    Communications biology 7 (1), 1026 , 2024
    2024
    Citations: 38

MOST CITED SCHOLAR PUBLICATIONS

  • MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data.
    V Modhukur, T , Iljasenko, T Metsalu, K Lokk, J Laisk-Podar, Triin and Vilo
    Epigenomics , 2018
    2018
    Citations: 567
  • DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
    K Lokk, V Modhukur, B Rajashekar, K Märtens, R Mägi, R Kolde, ...
    Genome Biology 15 (4) , 2014
    2014
    Citations: 525
  • The influence of menstrual cycle and endometriosis on endometrial methylome
    S Merli, M Vijayachitra, S Marina, R Balaji, R Kadri, S Denissa, K Helle, ...
    Clinical Epigenetics 8 (2), 1-10 , 2016
    2016
    Citations: 78
  • Uterine fluid microRNAs are dysregulated in women with recurrent implantation failure
    C Von Grothusen, C Frisendahl, V Modhukur, PG Lalitkumar, M Peters, ...
    Human Reproduction 37 (4), 734-746 , 2022
    2022
    Citations: 64
  • Glycosyltransferase functions of E. coli O-antigens
    M Lundborg, V Modhukur, G Widmalm
    Glycobiology 20 (3), 366-368 , 2010
    2010
    Citations: 52
  • DNA methylation changes in endometrium and correlation with gene expression during the transition from pre-receptive to receptive phase
    V Kukushkina, V Modhukur, M Suhorutšenko, M Peters, R Mägi, ...
    Scientific reports 7 (1), 3916 , 2017
    2017
    Citations: 51
  • Machine Learning Approaches to Classify Primary and Metastatic Cancers Using Tissue of Origin-Based DNA Methylation Profiles
    V Modhukur, S Sharma, M Mondal, A Lawarde, K Kask, R Sharma, ...
    Cancers 13 (15), 16 , 2021
    2021
    Citations: 46
  • Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicine
    K Sahoo, P Lingasamy, M Khatun, SL Sudhakaran, A Salumets, ...
    Epigenetics & chromatin 18 (1), 35 , 2025
    2025
    Citations: 45
  • Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level
    M Sarsenova, A Lawarde, ADS Pathare, M Saare, V Modhukur, ...
    Communications biology 7 (1), 1026 , 2024
    2024
    Citations: 38
  • MethSurv: A web tool to perform multivariable survival analysis using DNA methylation data. Epigenomics 10, 277–288
    V Modhukur, T Iljasenko, T Metsalu, K Lokk, T Laisk-Podar, J Vilo
    2018
    Citations: 34
  • Users’ Concerns About Endometriosis on Social Media: Sentiment Analysis and Topic Modeling Study
    R Goel, V Modhukur, K Täär, A Salumets, R Sharma, M Peters
    Journal of Medical Internet Research , 2023
    2023
    Citations: 31
  • Exploring immunome and microbiome interplay in reproductive health: current knowledge, challenges, and novel diagnostic tools
    P Lingasamy, V Modhukur, R Mändar, A Salumets
    Seminars in reproductive medicine 41 (05), 172-189 , 2023
    2023
    Citations: 21
  • Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders
    A Pauliina, V Jussi, M Heidi, M Vijayachitra, S Joonas, W Essi, R Karit, ...
    BMC Medicine , 2022
    2022
    Citations: 16
  • MBMethPred: A Computational Framework for the Accurate Classification of Childhood Medulloblastoma Subgroups Using Data Integration and AI-Based Approaches
    E Sharif Rahmani, A Lawarde, P Lingasamy, S Vela Moreno, A Salumets, ...
    Frontiers in Genetics 14 , 2023
    2023
    Citations: 14
  • MethSurv: a web tool to perform multivariable survival analysis using DNA methylation data. Epigenomics. 2018; 10 (3): 277–88
    V Modhukur, T Iljasenko, T Metsalu, K Lokk, T Laisk-Podar, J Vilo
    2017
    Citations: 13
  • ExplORRNet: an interactive web tool to explore stage-wise miRNA expression profiles and their interactions with mRNA and lncRNA in human breast and gynecological cancers
    A Lawarde, ES Rahmani, A Nath, D Lavogina, J Jaal, A Salumets, ...
    Non-coding RNA Research 9 (1), 125-140 , 2024
    2024
    Citations: 12
  • Increased risk of Graves ophthalmopathy in patients with increasing TRAb after radioiodine treatment and the impact of CTLA4 on TRAb titres
    B Shahida, K Tsoumani, T Planck, V Modhukur, P Asp, A Sundlöv, ...
    Endocrine 75 (3), 856-864 , 2022
    2022
    Citations: 11
  • Erratum to: DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns
    K Lokk, V Modhukur, B Rajashekar, K Märtens, R Mägi, R Kolde, ...
    Genome biology 17, 224 , 2016
    2016
    Citations: 9
  • Next Generation Sequencing Analysis of Lung Cancer Datasets: A Functional Genomics Perspective
    P Pappu, D Madduru, M Chandrasekharan, V Modhukur, S Nallapeta, ...
    Indian Journal of Cancer 53 (1), 1-7 , 2016
    2016
    Citations: 9
  • Tumor Tissue-of-Origin Classification Using miRNA-mRNA-lncRNA Interaction Networks and Machine Learning Methods
    A Lawarde, M Khatun, P Lingasamy, A Salumets, V Modhukur
    Frontiers in Bioinformatics 5, 1-29 , 2025
    2025
    Citations: 6