Pediatrics, Perinatology and Child Health, Infectious Diseases
3
Scopus Publications
27
Scholar Citations
3
Scholar h-index
Scopus Publications
Risk factors of immature retina on the first screening for retinopathy of prematurity Wedi Iskandar Kartamihardja, Gilang Mutiara, Yanuar Zulkifli Harun, Maulya Listrianti, Bestari Yuniah, Mayasari Kuntoyo Paediatrica Indonesiana Paediatrica Indonesiana, 2023 Background Immature retina is characterized by peripheral retinal avascularity. Retinal development is influenced by risk factors that affect retinal maturity.
 Objective To identify risk factors for immature retina on the first retinopathy of prematurity (ROP) screening at the Neonatology Care Unit, Al-Islam Hospital, Bandung, in 2013-2021.
 Methods This case-control, retrospective, observational study was performed by evaluating medical records of preterm infants screened for ROP. The subjects were divided into two groups, immature retina and mature retina. We recorded potential risk factors including gestational age (GA), birth weight (BW), birth weight for gestational age, respiratory distress syndrome (RDS), oxygen therapy >7 days, asphyxia, sepsis, multiple transfusion, apnea of prematurity (AOP), patent ductus arteriosus (PDA), and bronchopulmonary dysplasia (BPD) and analyzed them for potential associations with retinal development.
 Results On the first ROP screening of 203 premature infants, 5 (2.5%) had ROP, 90 (44.6%) had immature retinas, and 107 (53.0%) had mature retinas. Bivariate logistic regression analysis showed significant relationships between immature retina (P<0.05), GA (OR=0.575; P=0.000), BW (OR=0.997; P=<0.001), gestational age maturity (OR=2.639; P=0.006), RDS (OR=1.809; P=0.042), oxygen therapy of >7 days (OR=4.494; P=0.002), sepsis (OR=2.028; P=0.034), multiple transfusions (OR=4.656; P=0.000), AOP (OR=2.553; P=0.002), PDA (OR=2.119; P=0.030). Multivariate regression analysis revealed a significant simultaneous relationship between all the risk factors and immature retina, with a Nägelkerke R2 value of 0.421.
 Conclusion GA, BW, gestational age maturity, oxygen therapy of >7 days, sepsis, multiple transfusions, AOP, and PDA are significant risk factors of immature retina, be it independently or simultaneously.
Congenital neurosyphilis presenting as neonatal sepsis Wedi Iskandar, Vidi Permatagalih, Aris Primadi, Uni Gamayani Journal of Infection in Developing Countries, 2022 Introduction: Congenital syphilis involves any organs with various symptoms, including neurological signs. Neurosyphilis is a severe syphilis complication that can develop at any stage of illness.
 Case presentation: A 2,520 g male infant was spontaneously born at term from an untreated syphilis mother. Physical examination revealed decreased consciousness, respiratory distress, seizure, but without neurologic abnormality sign. The serum and cerebrospinal fluid Venereal Disease Research Laboratory and Treponemal Pallidum Hemagglutination Assay TPHA tests titters were 1:16 and 1:1,280, respectively. The diagnosis at admission was respiratory failure and neonatal sepsis. The infant was mechanically ventilated and treated with early management of sepsis. Blood culture was sterile later on. Then, the infant was administered intramuscular benzathine penicillin G (50,000 units/kg/dose) for a total of three weeks. The infant's condition was improved during the treatment.
 Conclusions: There are many challenges associated with screening and monitoring neurosyphilis in congenital syphilis. Congenital syphilis presenting as sepsis is easily misdiagnosed as bacterial sepsis.
Survival of Respiratory Failure within the First 72 Hours in Preterm Infants with Respiratory Distress Based on the Downes Score Assessment Wedi Iskandar, Hana Sofia Rachman, Vidi Permata Galih, Forestiera Qadriq Indikurnia, Muhammad Faishal Hafizh Iranian Journal of Neonatology, 2022 Background: Respiratory distress in neonates is the most common condition of preterm infants receiving treatment in the neonatal intensive care unit. As a clinical assessment of respiratory distress, the Downes score can predict the risk of respiratory failure. The present study aimed to determine the survival of respiratory failure in the first 72 h in preterm infants with respiratory distress based on the Downes score assessment.Methods: A prospective cohort survival analysis was performed at three hospitals in Indonesia (Al-Islam Hospital, Bandung, Al-Ihsan Hospital, Bandung, and Cibabat Hospital, Cimahi) from April to July 2021. Subjects were infants aged 28-36 weeks, with respiratory distress based on the Downes score within the first 2, 6, 12, 24, 48, and 72 h after delivery. The analyzed variables included birth weight ([BW], <1500 vs. 1500-2500 g), gestational age ([GA], 28-32 vs. 32-37 weeks), and 5-min APGAR score (<7 vs. >7). Bivariate and multivariate analyses were conducted with Cox regression proportional hazard and the Kaplan-Meier estimate of survival rate was also performed. In addition, the adjusted hazard ratio (aHR) was calculated, and a P-value of less than 0.05 was considered statistically significant.Results: Of the 89 subjects who met the criteria, 20 (22.47%) experienced respiratory failure. The multivariate analysis including BW (aHR: 1.846, 95%CI: 0.570-5.979, P> 0.05), GA (aHR: 2.273, 95 %CI: 0.697-7.416, P>0.05), and the 5-min APGAR score (aHR: 2.049, 95%CI: 0.811-5.179, P>0.05) estimated the survival rate for respiratory failure at the age of 72 h at 74.7% (standard error: 0.05%).Conclusion: A GA of <32 weeks, a BW of <1500 g, and the condition of asphyxia simultaneously increased the aHR of respiratory failure, with an estimated survival rate of 74.7%.
RECENT SCHOLAR PUBLICATIONS
Pendampingan Usaha Kesehatan Gigi dan Mulut pada Anak Sekolah Dasar Islam Terpadu Al Fitrah, Kecamatan Ranca Sari, Kota Bandung W Iskandar, M Iqbal, LM Kurniawati, Y Triyani Idea: Jurnal Humaniora 4 (1), 23-29 , 2025 2025
Evaluating Risk Factors for Late-onset Neonatal Sepsis W Iskandar, RD Juniartho, Y Triyani, V Permatagalih Global Medical & Health Communication (GMHC) 13 (2), 108–114-108–114 , 2025 2025
Evaluating Risk Factors for Early-onset Neonatal Sepsis W Iskandar, RD Juniartho, Y Triyani, V Permatagalih GLOBAL MEDICAL & HEALTH COMMUNICATION Учредители: Universitas Islam Bandung … , 2024 2024 Citations: 1
Hubungan Suplementasi Vitamin D dengan Pencegahan dan Pengobatan Tuberkulosis pada Anak AY Fadhilah, H Garna, W Iskandar Jurnal Riset Kedokteran, 31-36 , 2023 2023 Citations: 1
Risk factors of immature retina on the first screening for retinopathy of prematurity WI Kartamihardja, G Mutiara, YZ Harun, M Listrianti, B Yuniah, M Kuntoyo Paediatrica Indonesiana 63 (3), 189-94 , 2023 2023
Risk factors of immature retina on the first screening for retinopathy of prematurity. W Iskandar, G Mutiara, YZ Harun, M Listrianti, B Yuniah, M Kuntoyo Paediatrica Indonesiana 63 (3) , 2023 2023
PKM MANAJEMEN LAKTASI DALAM UPAYA PENURUNAN STUNTING DI KABUPATEN BANDUNG BARAT M Putri, W Iskandar, W Maharani, MF Afif, RS Prawiradilaga DHARMAKARYA: Jurnal Aplikasi Ipteks untuk Masyarakat 12 (4), 481-485 , 2023 2023
Hubungan Prematuritas dengan Keterlambatan Bicara pada Anak Usia Dua sampai Lima Tahun FO Duwandani, W Iskandar, C Tresnasari Jurnal Riset Kedokteran, 15-20 , 2022 2022 Citations: 9
Congenital neurosyphilis presenting as neonatal sepsis W Iskandar, V Permatagalih, A Primadi, U Gamayani The Journal of Infection in Developing Countries 16 (06), 1113-1117 , 2022 2022 Citations: 8
Survival of Respiratory Failure within the First 72 Hours in Preterm Infants with Respiratory Distress Based on the Downes Score Assessment. W Iskandar, HS Rachman, VP Galih, FQ Indikurnia, MG Hafizh Iranian Journal of Neonatology 13 (2) , 2022 2022 Citations: 1
Systematic review: Perbandingan efektivitas pemberian terapi ivermektin dengan permetrin pada pengobatan skabies R Meidina, RDI Astuti, W Iskandar Jurnal Integrasi Kesehatan & Sains 3 (2), 142-147 , 2021 2021 Citations: 3
The influence of gestational age and birth weight on neonatal mortality W Iskandar, Y Andayani, L Marlia, B Burhan, A Primadi Global Medical & Health Communication (GMHC) 8 (3) , 2020 2020 Citations: 4
MOST CITED SCHOLAR PUBLICATIONS
Hubungan Prematuritas dengan Keterlambatan Bicara pada Anak Usia Dua sampai Lima Tahun FO Duwandani, W Iskandar, C Tresnasari Jurnal Riset Kedokteran, 15-20 , 2022 2022 Citations: 9
Congenital neurosyphilis presenting as neonatal sepsis W Iskandar, V Permatagalih, A Primadi, U Gamayani The Journal of Infection in Developing Countries 16 (06), 1113-1117 , 2022 2022 Citations: 8
The influence of gestational age and birth weight on neonatal mortality W Iskandar, Y Andayani, L Marlia, B Burhan, A Primadi Global Medical & Health Communication (GMHC) 8 (3) , 2020 2020 Citations: 4
Systematic review: Perbandingan efektivitas pemberian terapi ivermektin dengan permetrin pada pengobatan skabies R Meidina, RDI Astuti, W Iskandar Jurnal Integrasi Kesehatan & Sains 3 (2), 142-147 , 2021 2021 Citations: 3
Evaluating Risk Factors for Early-onset Neonatal Sepsis W Iskandar, RD Juniartho, Y Triyani, V Permatagalih GLOBAL MEDICAL & HEALTH COMMUNICATION Учредители: Universitas Islam Bandung … , 2024 2024 Citations: 1
Hubungan Suplementasi Vitamin D dengan Pencegahan dan Pengobatan Tuberkulosis pada Anak AY Fadhilah, H Garna, W Iskandar Jurnal Riset Kedokteran, 31-36 , 2023 2023 Citations: 1
Survival of Respiratory Failure within the First 72 Hours in Preterm Infants with Respiratory Distress Based on the Downes Score Assessment. W Iskandar, HS Rachman, VP Galih, FQ Indikurnia, MG Hafizh Iranian Journal of Neonatology 13 (2) , 2022 2022 Citations: 1
Pendampingan Usaha Kesehatan Gigi dan Mulut pada Anak Sekolah Dasar Islam Terpadu Al Fitrah, Kecamatan Ranca Sari, Kota Bandung W Iskandar, M Iqbal, LM Kurniawati, Y Triyani Idea: Jurnal Humaniora 4 (1), 23-29 , 2025 2025
Evaluating Risk Factors for Late-onset Neonatal Sepsis W Iskandar, RD Juniartho, Y Triyani, V Permatagalih Global Medical & Health Communication (GMHC) 13 (2), 108–114-108–114 , 2025 2025
Risk factors of immature retina on the first screening for retinopathy of prematurity WI Kartamihardja, G Mutiara, YZ Harun, M Listrianti, B Yuniah, M Kuntoyo Paediatrica Indonesiana 63 (3), 189-94 , 2023 2023
Risk factors of immature retina on the first screening for retinopathy of prematurity. W Iskandar, G Mutiara, YZ Harun, M Listrianti, B Yuniah, M Kuntoyo Paediatrica Indonesiana 63 (3) , 2023 2023
PKM MANAJEMEN LAKTASI DALAM UPAYA PENURUNAN STUNTING DI KABUPATEN BANDUNG BARAT M Putri, W Iskandar, W Maharani, MF Afif, RS Prawiradilaga DHARMAKARYA: Jurnal Aplikasi Ipteks untuk Masyarakat 12 (4), 481-485 , 2023 2023
