PhD from Osmania University
MPhil from Vinayaka missions University
MSc Chemistry from Osmania University College for Women
from Osmania University College for Women
Intermediate from Mother's Girls
X (ICSE) from Sri Sai Public School.
RESEARCH INTERESTS
Organic synthesis of heterocyclic compounds bearing oxazole, imidazole and imidazolone rings. Molecular docking studies and and bacterial studies
1-(3-acetyl phenyl)-4-(4-arylidene)-2-phenyl-1h-imidazol-5(4h)-ones: Synthesis, spectroscopic characterization, antimicrobial and molecular docking studies Y. Aparna, D. Sandhya, N. J. P. Subhashini, L. N. Sharada Rasayan Journal of Chemistry, 2021 Imidazole rings are privileged moieties in heterocyclic chemistry since they permit functional group and structural modifications to synthesize abundant substituted heterocycles. Thus, the pursuit of exploring many more alterations on imidazole moiety needs to be continued. In the present work an array of the new imidazolone derivatives was prepared as per the expedient method. The moieties were characterized by FTIR,1HNMR, 13CNMR and Mass spectra. Docking was studied to exemplify the binding connections of intended scaffolds with the crystal structure of proteinreductase of Staphylococcusaureus pdbid:4NZ9.The synthesized compounds were tested for antibacterial activity by the agar diffusion method. All the compounds showed potent activity against diverse bacterial species.
Substituted Arylidene Imidazolones: Synthesis, Spectral Characterization and Molecular Docking Studies Y Aparna, NJP Subhashini Chemistry and Biochemistry: Research Progress Vol. 9, 103-113 , 2026 2026
Microwave assisted synthesis of new quinolone and coumarin molecular hybrids: SAR, molecular modelling studies as dual antagonists and its antimicrobial evaluation targeting … TL Viveka, G Angajala, V Aruna, M Nakka, Y Aparna Journal of Molecular Structure 1303, 137482 , 2024 2024 Citations: 4
ANTIBACTERIAL ACTIVITY AND RELATED ISSUES OF NATURAL DYES IN TEXTILES, THEIR EFFECTIVE DATA ANALYSIS YA K. Sai Srikari , T. Vishnu , K. Nagaiah Heterocyclic Letters 13 (4), 737-745 , 2023 2023
Synthesis, Antimicrobial Evaluation, and In Silico Molecular Docking Studies of Chalcone-Based 1,2,3-Triazoles BPYA Ch. Prasad, P. Nagesh, Ch. Kishan, V. Murali Krishna, A. Balaswamy, V ... Russian journal of General Chemistry 93 (5), 1162 - 1170 , 2023 2023 Citations: 3
An Assessment on Oxazolones-their Reactions and Applications Y Aparna Novel Aspects on Chemistry and Biochemistry Vol. 1 1, 121-136 , 2023 2023
ANTIFUNGAL ACTIVITY, MOLECULAR DOCKING ON COVID-19 MAIN PROTEASE AND PHARMACOKINETICS OFIMIDAZOLONE ANALOGUES YA T.Vishnua ,K.Sandhyaa ,K.ArunaKumaria Heterocyclic letters 13 (1), 93-104 , 2023 2023
A Heterogeneous approach to synthesis of azlactones Y Aparna International journal of Pharmaceutical research and applications 7 (02 … , 2022 2022
Synthesis, Spectral characterization, DNA binding, and Antimicrobial studies of Cu(II), Ni(II) and Co(II) Binary metal complexes derived from 1-(2- methyl-1H-indol-5-ylimino … YA L.N.Sharada, Maryam Sabha, SNT Sunita International Journal of research and analytical reviews 8 (5), 837-849 , 2021 2021
1-(3-ACETYL PHENYL)-4-(4-ARYLIDENE)-2-PHENYL-1H-IMIDAZOL-5 (4H)-ONES: SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, ANTIMICROBIAL AND MOLECULAR DOCKING STUDIES Y Aparna, D Sandhya, NJP Subhashini, LN Sharada Rasayan Journal of Chemistry 14 (4) , 2021 2021
A comparative study of Oxazolones and imidazolones-A review Y Aparna IJARBEST 7 (9), 16-34 , 2021 2021
Cytotoxic activity, corrosion inhibition activity and molecular docking studies of Imidazolone scaffolds-A review LNS Y Aparna1 , NJP Subhashini2 International Journal of Advanced Chemistry Research 3 (1, 2021), 19-24 , 2021 2021
Synthesis and Antimicrobial Activity of Novel Bis-1,2,3-triazol-1 H -4-yl-substituted Aryl Benzimidazole-2-thiol Derivatives Y Aparna, G Nirmala, NJP Subhashini, LN Sharada, S Sreekanth Russian Journal of General Chemistry 90 (8), 1501-1506 , 2020 2020 Citations: 15
Ternary Cu (II) complexes: synthesis, structural elucidation, and biological studies (DNA binding, cleavage, antibacterial, cytotoxicity) LN Sharada, SNT Sunitha, M Sabha, TL Viveka, Y Aparna, M Prasad Research on Chemical Intermediates 46 (7), 3341-3360 , 2020 2020 Citations: 10
Synthesis, Characterization, Molecular Docking, and Antimicrobial Activity of New Arylidene-Substituted Imidazoles Y Aparna, LN Sharada, NJP Subhashini, S Sreekanth Russian Journal of General Chemistry 89 (6), 1202-1208 , 2019 2019 Citations: 7
ANTIMICROBIAL & ANTIFUNGAL ACTIVITY OF SUBSTITUTED 4-ARYLIDENE 2-(HYDROXY PHENYL) OXAZOL-5(4H)-ONES LNS 1Y. Aparna International Journal of Creative Research Thoughts, 346-352 , 2018 2018
Synthesis, Characterization and Molecular Docking Studies Of New Erlenmeyer Azlactones LV 1Prof L. N. Sharada*, 2Y.Aparna, 3Saba, 4Sunita IOSR Journal of Applied Chemistry (IOSR-JAC) 8 (Issue 8 Ver. II), PP 30-36 , 2015 2015
A Review on Reactions and Applications of Oxazolones LN Sharada, Y Aparna, M Saba, SNT Sunitha, L Viveka International Journal of Scientific and Research Publication 5, 1-9 , 2015 2015 Citations: 9
SYNTHESIS AND ANTI-MICROBIAL AGENTS OF NOVEL (E)-N'-4, 4’-DIFLUORO-CYCLOHEXANECARBOXYLIC ACID (SUBSTITUTED-BENZYLIDENE)-HYDRAZIDE DERIVATIVES LNS Tella.Lakshmi Viveka, Mariyam Saba, S.N.T.Sunitha, Y.Aparna WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES 4 (05), 1087-1105 , 2015 2015
Azlactones in heterocyclic synthesis: Part-V-Condensation of Azlactones with 4-nitrobenzene-1, 2-diamine Y Aparna, NJP Subhashini J. Chem. Pharm. Res 2 (3), 473-477 , 2010 2010
MOST CITED SCHOLAR PUBLICATIONS
Synthesis and Antimicrobial Activity of Novel Bis-1,2,3-triazol-1 H -4-yl-substituted Aryl Benzimidazole-2-thiol Derivatives Y Aparna, G Nirmala, NJP Subhashini, LN Sharada, S Sreekanth Russian Journal of General Chemistry 90 (8), 1501-1506 , 2020 2020 Citations: 15
Ternary Cu (II) complexes: synthesis, structural elucidation, and biological studies (DNA binding, cleavage, antibacterial, cytotoxicity) LN Sharada, SNT Sunitha, M Sabha, TL Viveka, Y Aparna, M Prasad Research on Chemical Intermediates 46 (7), 3341-3360 , 2020 2020 Citations: 10
A Review on Reactions and Applications of Oxazolones LN Sharada, Y Aparna, M Saba, SNT Sunitha, L Viveka International Journal of Scientific and Research Publication 5, 1-9 , 2015 2015 Citations: 9
Synthesis, Characterization, Molecular Docking, and Antimicrobial Activity of New Arylidene-Substituted Imidazoles Y Aparna, LN Sharada, NJP Subhashini, S Sreekanth Russian Journal of General Chemistry 89 (6), 1202-1208 , 2019 2019 Citations: 7
Microwave assisted synthesis of new quinolone and coumarin molecular hybrids: SAR, molecular modelling studies as dual antagonists and its antimicrobial evaluation targeting … TL Viveka, G Angajala, V Aruna, M Nakka, Y Aparna Journal of Molecular Structure 1303, 137482 , 2024 2024 Citations: 4
Synthesis, Antimicrobial Evaluation, and In Silico Molecular Docking Studies of Chalcone-Based 1,2,3-Triazoles BPYA Ch. Prasad, P. Nagesh, Ch. Kishan, V. Murali Krishna, A. Balaswamy, V ... Russian journal of General Chemistry 93 (5), 1162 - 1170 , 2023 2023 Citations: 3
Substituted Arylidene Imidazolones: Synthesis, Spectral Characterization and Molecular Docking Studies Y Aparna, NJP Subhashini Chemistry and Biochemistry: Research Progress Vol. 9, 103-113 , 2026 2026
ANTIBACTERIAL ACTIVITY AND RELATED ISSUES OF NATURAL DYES IN TEXTILES, THEIR EFFECTIVE DATA ANALYSIS YA K. Sai Srikari , T. Vishnu , K. Nagaiah Heterocyclic Letters 13 (4), 737-745 , 2023 2023
An Assessment on Oxazolones-their Reactions and Applications Y Aparna Novel Aspects on Chemistry and Biochemistry Vol. 1 1, 121-136 , 2023 2023
ANTIFUNGAL ACTIVITY, MOLECULAR DOCKING ON COVID-19 MAIN PROTEASE AND PHARMACOKINETICS OFIMIDAZOLONE ANALOGUES YA T.Vishnua ,K.Sandhyaa ,K.ArunaKumaria Heterocyclic letters 13 (1), 93-104 , 2023 2023
A Heterogeneous approach to synthesis of azlactones Y Aparna International journal of Pharmaceutical research and applications 7 (02 … , 2022 2022
Synthesis, Spectral characterization, DNA binding, and Antimicrobial studies of Cu(II), Ni(II) and Co(II) Binary metal complexes derived from 1-(2- methyl-1H-indol-5-ylimino … YA L.N.Sharada, Maryam Sabha, SNT Sunita International Journal of research and analytical reviews 8 (5), 837-849 , 2021 2021
1-(3-ACETYL PHENYL)-4-(4-ARYLIDENE)-2-PHENYL-1H-IMIDAZOL-5 (4H)-ONES: SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION, ANTIMICROBIAL AND MOLECULAR DOCKING STUDIES Y Aparna, D Sandhya, NJP Subhashini, LN Sharada Rasayan Journal of Chemistry 14 (4) , 2021 2021
A comparative study of Oxazolones and imidazolones-A review Y Aparna IJARBEST 7 (9), 16-34 , 2021 2021
Cytotoxic activity, corrosion inhibition activity and molecular docking studies of Imidazolone scaffolds-A review LNS Y Aparna1 , NJP Subhashini2 International Journal of Advanced Chemistry Research 3 (1, 2021), 19-24 , 2021 2021
ANTIMICROBIAL & ANTIFUNGAL ACTIVITY OF SUBSTITUTED 4-ARYLIDENE 2-(HYDROXY PHENYL) OXAZOL-5(4H)-ONES LNS 1Y. Aparna International Journal of Creative Research Thoughts, 346-352 , 2018 2018
Synthesis, Characterization and Molecular Docking Studies Of New Erlenmeyer Azlactones LV 1Prof L. N. Sharada*, 2Y.Aparna, 3Saba, 4Sunita IOSR Journal of Applied Chemistry (IOSR-JAC) 8 (Issue 8 Ver. II), PP 30-36 , 2015 2015
SYNTHESIS AND ANTI-MICROBIAL AGENTS OF NOVEL (E)-N'-4, 4’-DIFLUORO-CYCLOHEXANECARBOXYLIC ACID (SUBSTITUTED-BENZYLIDENE)-HYDRAZIDE DERIVATIVES LNS Tella.Lakshmi Viveka, Mariyam Saba, S.N.T.Sunitha, Y.Aparna WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES 4 (05), 1087-1105 , 2015 2015
Azlactones in heterocyclic synthesis: Part-V-Condensation of Azlactones with 4-nitrobenzene-1, 2-diamine Y Aparna, NJP Subhashini J. Chem. Pharm. Res 2 (3), 473-477 , 2010 2010