HISTOLOGICAL EFFECT OF HPC HORMONE ON BONE HEALING AFTER ITS APPLICATION ON SURGICALLY CREATED DEFECT HUDA A. SALIM, MOHANAD ALFAHAD, ZIAD HAZIM DELEME Assiut Veterinary Medical Journal Egypt, 2024 Bone is highly vascularized living connective tissue responsible for important metabolic and mechanical functions. Progesterone was first isolated in 1934 by groups investigating the endocrine function of the corpus luteum. Sixty adult male domestic rabbits were selected, with an average weight of 1750 g and an age range of 8 to 10 months. After the rabbit was anesthetized, an incision 4 cm in length was made in the left leg above the femoral bone, followed by dissection of the muscle, fascia, and periosteum to expose the femoral bone. Two holes were made with a round bur of 3 mm, and the space between holes is about 1 cm. Each hole is away from the edge of the femoral bone by 1 cm. In the control negative group, the two holes were lifted without filling with any material, while in the control positive group, the two holes were filled by placement of gel-foam pieces, and in the study group, the holes were filled with gel-foam, which was soaked in hydroxyprogesterone caproate. The study group showed a closed defect faster than the other two groups; in seven days, it showed a narrow defect bone site area between the edge of the old bone under its granulation tissue, connective tissue with high new bone formation, cartilaginous tissue, and well angiogenesis, with a significance of p-value 0.033. In conclusion, HPC accelerates bone healing in different time intervals by activating osteoblasts to form bone.
Oral and Maxillofacial Lesions in COVID 19 Infection from Mosul Hospital in Iraq: Epidemiological Study and Approach to Classification and Treatment. Alyaa Ismael Naser, Marwa Nazar Al-Sarraj, Ziad H. Deleme, and Journal of Oral Research, 2021 During the COVID-19 pandemic, many manifestations of the disease appear in the oral, perioral and maxillofacial regions, either related to the virus itself or to the drugs used in the treatment. Aim: This study aims to identify the most common oral and perioral lesions in hospitalized patients with COVID-19 in the city of Mosul and their management; and also to evaluate the incidence and prevalence of these lesions. Material and Methods: Prospective study included 338 patients (138 females, 200 males) who had positive PCR results for SARS-CoV-2, with oral manifestations. All data were analyzed taking the means, frequencies, and percentage. Results: The most common lesions were colored lesions (31%) and stomatalgia (27%). The most common oral disorder and prior comorbidity combination was stomatalgia in patients with a history of hypertension. The most common associated systemic diseases were diabetes mellitus (19%) followed by hypertension (17%). Macular lesions had a higher response to drugs (40%) followed by stomatalgia (28%), in comparison with necrotic lesions (0%). Treatment of oral lesions included surgical interventions (26%) as well as conventional medical treatment (74%). Conclusion: Oral and perioral disorders during COVID-19 are transitory and more evidence is warranted to efficiently address these comorbidities in the short term.
Estimation of time utilized in suturing of oral flaps post-surgical wisdom teeth removal using negus knot pusher instrument (A comparative study) Noor Sulaiman, Ziad Deleme, Saif Ali Brazilian Dental Science, 2021 Wisdom teeth were the most common teeth affected among the rest of the teeth, these teeth need accurate evaluation and diagnosis, surgical removal of impacted wisdom needs time for incision, bone removal and suture, so the use of any instrument helps to reduce this time is essential. Objective The objectives of this study were to estimate the time needed for the suture of oral flaps post-surgical removal of the lower wisdom teeth by using Negus knot pusher and compare it with the time used for stitching in conventional manual holding single stitching. Material and Methods: Data had been collected from thirty patients through history, clinical examination and radiographic assessment, followed by classical surgical removal performed on the same principles for all patients, at the suture level patients divided arbitrarily into two groups, control group 15 patients and 15 patients Negus pusher group, using Negus knot pusher, which is usually used to hold the stitch and stop bleeding post tonsillectomy operations by ligation, time elapsed for suturing with knot tying is calculated for both groups. Results: Among the 30 patients incorporated in the clinical study, control group mean was (1 minutes and 11 seconds and 70 milliseconds) while for the pusher group was (1 minutes and 32 seconds and 57 milliseconds), the comparison by means of T-test was not significant with the (0.424) value. Conclusion: the Negus pusher instrument can be used for the knotting stiches post wisdom teeth removal as an auxiliary tool and the time can be shortened by the use of a modified handling technique and more satisfaction for patients. Keywords Time; Suturing; Wisdom teeth; Negus knot pusher.
The effects of bioadhesive hyaluronic acid gel versus diclofenac after surgical removal of impacted wisdom teeth Abdul Hammed N, Ziad H. Deleme, and Journal of Oral Research, 2019 Surgical extraction of impacted lower wisdom teeth is a frequent minor intraoral surgical process. It is regularly linked with aching and postoperative consequences as pain and swelling. The aim of this study is to evaluate the efficacy of two methods in reducing swelling and pain subsequent to the removal of impacted wisdom teeth. This randomized study incorporated 20 patients with impacted wisdom teeth of different surgical complexity. Topical hyaluronic acid gel 2g/2ml with aloe vera (Kin®Care) was given to the patients to be applied to the surgical area three times a day, or diclofenac sodium tablet 50mg (Voltaren®) to be taken every eight hours, for one week. Swelling was estimated using a strip gauge technique, and pain with a visual analogue scale. Evaluations were made on day one of surgical treatment and on 72hrs and one week later. Statistically no significant differences were identified regarding the swelling and pain values between the two treatment groups on the third and seventh day after surgery. Hyaluronic acid gel was as efficient as diclofenac tablets in reducing the two parameters. The use of hyaluronic acid may be advantageous in medically compromised patient such as those with hypertension, chronic asthma, gastric ulcers or in those with any contraindications to using non-steroidal anti-inflammatory drugs, or in pregnant patients to reduce pain and swelling subsequent to impacted wisdom teeth surgery.
Publications
1 Incidence of Mandibular Fractures Associated with Head Injury in Ninavah Governorate (2006-2007) Al–Rafidain Dent J. 2011; 11(2): 370-375.
2 Oral and Rectal Sedation with Diazepam for Uncooperative Child during Dental Procedure Al–Rafidain Dent J. 2012; 12(2): 321-328.
3 The Impact of General and Local Factors as Criterions of Assessment for the Difficult Lower Wisdom Tooth. A Retrospective Study Al–Rafidain Dent J. 2014; 14(1):115-122.
4 Evaluation of Some Properties of Prepared Indomethacin Mouth Wash and Its Effect on Gingival Index Score Al–Rafidain Dent J. 2014; 14(2):259-265.
5 The Use of Three Different Suturing Techniques for Wound Closure of Mucoperiosteal Flaps After Surgical Removal of Impacted Lower Wisdom Teeth (Comparative Study) Al–Rafidain Dent J. 2017; 17(1):98-107.
6 Assessment of Peri Implant Osteal Changes by Radiographic Evaluation Using Standard Orthopantomograph and Periapical View a Retrospective Study Al–Rafidain Dent J. 2018,18(1):59-66.
7 Inter oral surgeon’s estimation and performance of dental implant as a restoration of oral occlusal integrity (a survey study questionnaire) International Journal of Enhanced Research in Science, Technology & Engineering Vol. 7 Issue 5, May-2018,
8 The effects of bio adhesive hyaluronic acid gel versus diclofenac after surgical removal of impacted wisdom teeth. Journal of Oral Research Special Issue 2019;S1:28-31.
9 Kinesiology tape in comparison with oral Diclofenac sodium in reducing swelling after surgical removal of lower wisdom teeth Al–Rafidain Dent J. 2019;19(1):90-97.
10 The Effects of Bio Adhesive Chlorhexidine Gel, NSAIDs on Post-operative Sequelae after Periapical Surgery of Upper Anterior Teeth International Journal of Dental Sciences and Research,
2020, Vol. 8, No. 1, 27-30
