Mohammad Mahmoud Farhan Al-Halbosiy

Verified email at yahoo.com

Biotechnology Research Center, Al-Nahrain University
Al-Nahrain University



                                         

https://researchid.co/al-halbosiy

RESEARCH INTERESTS

Molecular Immunology and Animal Cell Culture

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Scopus Publications

Scopus Publications

  • The Role of Nkx-6.1 Gene Expression in Diabetic and Non-diabetic Patients
    International Journal of Drug Delivery Technology, eISSN: 09754415, Pages: 237-238, Published: January - March 2022

  • Bioactive levan-Type exopolysaccharide produced by Pantoea agglomerans ZMR7: Characterization and optimization for enhanced production
    Safaa A. S. Al-Qaysi, Halah Al-Haideri, Sana M. Al-Shimmary, Jasim M. Abdulhameed, Othman I. Alajrawy, Mohammad M. Al-Halbosiy, Tarek A. A. Moussa, and Mohamed G. Farahat

    Journal of Microbiology and Biotechnology, ISSN: 10177825, eISSN: 17388872, Pages: 696-704, Published: 1 May 2021 Journal of Microbiology and Biotechnology
    Levan is an industrially important functional biopolymer with considerable applications in food and pharmaceutical fields owing to its safety and biocompatibility. Herein, levan type exopolysaccharide (EPS) produced by Pantoea agglomerans ZMR7 was purified by cold ethanol precipitation and characterized using TLC, FTIR, 1H, and 13C NMR spectroscopy. The maximum production of levan (28.4 g/L) was achieved when sucrose and ammonium chloride were used as carbon and nitrogen sources, respectively, at 35 °C and an initial pH value of 8.0. Some biomedical applications of levan like antitumor, antiparasitic, and antioxidant activities were investigated in vitro. The results revealed the ability of levan at different concentrations to decrease the viability of rhabdomyosarcoma (RD) and breast cancer (MDA) cells compared with untreated cancer cells. Besides, levan appeared to have high antiparasitic activity against the promastigote of Leishmania tropica. Furthermore, levan had strong DPPH radical scavenging (antioxidant) activity. These findings suggest that levan produced by P. agglomerans ZMR7 can serve as a natural biopolymer candidate in pharmaceutical and medical fields.

  • Antimicrobial activity of locally synthesized carbon nanosphere on some pathogenic species of bacteria and parasites
    Baghdad Science Journal, ISSN: 20788665, eISSN: 24117986, Pages: 1-6, Published: 2021 College of Science for Women

  • Cytotoxic activity of green zinc selenide nanoparticles against Hep-G2 cell lines
    Indian Journal of Forensic Medicine and Toxicology, ISSN: 09739122, eISSN: 09739130, Pages: 2072-2078, Published: January-March 2021 Institute of Medico-legal Publications Private Limited

  • Effect gold nanoparticles generated by cold plasma for mineral blood
    M. F. Al-Halbosiy, Ban H. Adil, A. S. Obaid, Maryam Kays Abdullah, and Alzahraa fadhel adnan

    AIP Conference Proceedings, ISSN: 0094243X, eISSN: 15517616, Volume: 2307, Published: 15 December 2020 AIP Publishing

  • In vitro cytotoxicity study of Pt nanoparticles decorated TiO2 nanotube array
    Shaymaa Rajab Baqer, Abdulkareem Alsammarraie, Mahasin Alias, Mohammad Al-Halbosiy, and Amaal Sadiq

    Baghdad Science Journal, ISSN: 20788665, eISSN: 24117986, Pages: 1169-1176, Published: 1 December 2020 College of Science for Women
    Titanium dioxide nanotubes were synthesized by anodizing Ti sheets in the ethylene glycol solution and were covered in Pt nanoparticles onto the surface of TiO2NTs using electrodeposition method from using five derivatives of Mannich base Pt complexes which have been used as precursor of platinum. The mean size, shape, elemental composition of the titanium dioxide nanotubes and platinum deposited on the template were evaluated by different techniques such as field emission scanning electron microscope (FE-SEM), transmission electron microscopy (TEM), X-ray diffraction pattern (XRD), and energy dispersive X-ray (EDX) technique. From all these analyses, the TiO2NTs prepared and Ptnanoparticles deposited on it were identified. The diagnoses proved that all the Pt nanoparticles have a size less than 50 nm. The MCF-7 cancer cell lines and WRL68 normal cell lines were treated with concentration 800, 400,200,100, 50, 25, 12.5µg\\ml of TiO2NTs and Pt\\TiO2NTs(1) and (2) for 48hours using MTT assay.IC50 and inhibition rate were calculated. The result shows that the Pt\\TiO2NTs have more inhibition effect on cancer cell lines than TiO2NTs array.

  • Artemisinin efficacy against old world Leishmania donovani: in vitro and ex vivo study
    M. F. Al-Halbosiy, Hayder Z. Ali, G. M. Hassan and F. Ghaffarifar

    Annals of parasitology, ISSN: 22990631, Pages: 295-302, Published: 2020
    Visceral leishmaniosis is one of the most fatal old-world neglected disease with estimated 90 thousand worldwide cases emerge each year. In Iraq, the cutaneous and visceral form are endemic but available chemotherapies are either toxic with diverse side effects, expensive available drugs or parasite resistant is arising. Artemisinin (ART) is a semi-synthetic compound which proved its effectiveness against protozoan parasites, such as malaria and Leishmania. In this study, the efficacy of different concentrations of pure artemisinin was screened in vitro against promastigotes and axenic amastigotes by MTT assay after 24, 48 and 27 hours follow up. In addition, the infectivity ability and number was investigated of intra-cellular Leishman bodies in treated murine peritoneal macrophages after 24 and 48 hours ART treatment. The results verified ART efficacy against the promastigotes and axenic amastigotes viability with IC50 measured after 24, 48- and 72-hours treatment. Infectivity percentage of murine macrophages and parasite burden were significantly reduced in treated cells. These findings indicate the leishmanicidal activity of ART against the Iraqi isolate of L. donovani and further in vivo study is recommended for assigning ART as a natural anti visceral leishmaniosis compound.

  • Use of cold plasma in the synthesis of gold nanomaterials for parasitic leishmaniasis treatment
    International Journal of Plasma Environmental Science and Technology, ISSN: 18818692, Pages: 1-7, Published: 2020

  • Cloning and Expression of Truncated Haemoglobin Receptor of Leishmania tropica as a Vaccine Candidate
    May Ridha Jaafar, Yaseen Ismael Mamoori, and Mohammad Mahmoud Al-Halbosiy

    Annals of Tropical Medicine and Public Health, ISSN: 17556783, eISSN: 09746005, Published: 2020 Africa Health Research Organization
    Cutaneous leishmaniasis is a tropical disease caused byLeishmania parasiteand vaccination is the best way to control it.In this study, the truncatedHaemoglobin receptor (HbR-N) gene of Leishmaniatropicawas cloned and expressed in Escherichia coli.The sequence of this gene was codon-optimized, synthetically synthesized and amplified using specific primers. pTYB21 plasmid as well as the amplified gene were digested bySapI and PstI and ligated using T4 DNA ligase. The recombinant plasmid was used to transform DH5α Escherichia coli. Transformants were confirmed using colony PCR, digestion of the plasmids using PvuII enzyme as well as DNA sequencing. The recombinant plasmid was used to retransform the T7 express E. coli and the transformants were confirmed using colony PCR. The cell carrying the plasmid was used to express HbR-N protein. The gene expression was analysed by SDS-page polyacrylamide gels. PCR has successfully amplified the HbR-N gene with a molecular size of 398 bp.Transformants carrying the pTYB21_HbR-N plasmid were obtained and designated as MYM1. DNA sequencing showed 100% similarity to HbR gene. The later plasmid was used to retransform T7 express E. coli, several transformants were obtained and they designated as MYM2. The MYM2 bacterial cell was used to express the gene. Finally, SDS-page polyacrylamide gel showed protein bands of the fused protein (intein-HbR-N) with a molecular size of about 70 kDa. In this study, the HbR-N gene was cloned and expressed in E. coli and could be used as a potential vaccine against several Leishmania spp.

  • Polymorphisms of TGF-BETA1 gene (+869T/C) and risk factor in Iraqi Asthma Patients
    Biochemical and Cellular Archives, ISSN: 09725075, eISSN: 09761772, Pages: 1763-1767, Published: 2020

  • Biological activities of iraqi fig (Ficuscarica) crude ethanolic and total flavonoids extracts
    Mohammad Mahmoud Farhan Al-Halbosiy, Zainab Yaseen Mohammed Hasan, Farooq Ibrahem Mohammad, and Baraa Abdulhadi Abdulhameed

    Iraqi Journal of Science, ISSN: 00672904, eISSN: 23121637, Pages: 1612-1621, Published: 2020 University of Baghdad College of Science
    The present study focuses on the biological strategy for treating cancer and parasitic infections, such as leishmaniasis antiparasitic activity, forthe crude alcoholic extract ofFicus leaves and their extracted total flavonoids with a comparison between their effects.The flavonoids were extracted from the leaves of the mature Ficuscaricausing the reflux extraction method. Total flavonoids were detected qualitatively by TLC techniquewhich demonstratedthat the plant was rich indifferent flavonoids, especially Rutin, Quercetin, Kaempferol, luteolin and others. Quantitatively, the plant total flavonoids content was 337.3 mg / 100 g fig leaves calculated as rutin.The biologicaleffects of the crude and purified total flavonoid on cell lines (L-20B and MCF7) and two parasites (Leishmaniatropica ,Leishmaniadonvani) were investigated. Maximum growthinhibition rates forthe total flavonoids onthe cell linesL20B andMCF7 reached 43 % at the concentration of 0.169 mg/ml and 28% at the concentration of 2.7 mg/ml, respectively, in comparison with the negative control. The ethanoliccrude extract had a low effect on L20-B cell line, while the inhibition rate forMCF-7 cell linereached 34% at a concentration of 0.084 mg/ml. For Leishmaniatropica,the total flavonoid and crude plant extractcaused maximum inhibition rates of 48% and 56%, respectively,at a concentration of 2.7 mg/ml for both. Cytotoxicity valueon Leshmaniadonovani was 20% for the crude extract at 1.35 mg/ml concentration, whereas it was11% for the total flavonoids  at a concentration of 0.169 mg/ml. In conclusion, the differences in anticancer and anti-parasitic  activitiesareattributed to differentcompounds present in each extract.

  • Genetic study of thiopurin s-methyltransferase and nudix hydrolase genes in a sample of Iraqi children
    EurAsian Journal of BioSciences, eISSN: 13079867, Pages: 1065-1070, Published: 2020

  • The use of cold atmospheric plasma in pentostam enhancement as Leishmaniasis treatment in vitro
    Ban H. Adil, Mohammad M. Farhan Al-Halbosiy, and Hamid H. Murbat

    AIP Conference Proceedings, ISSN: 0094243X, eISSN: 15517616, Volume: 2190, Published: 11 December 2019 AIP Publishing
    This study illustrates in vitro effect of cold atmospheric plasma (CAP) on the treatment of Leishmania. In addition, the study evaluated the effect of drug treatment (pentostam) and the combination treatment of pentostan and CAP at different doses and incubation time 24 h in order to assess the most effective treatment. The duration of the cold plasma doses was 1 min, 2 min and 3 min, while the pentostam doses were 2.5 µg/ml and 5 µg/ml. The combinations therapies included combining the three cold plasma doses with the pentostam doses to test 6 combinations of treated in vitro. The maximum growth inhibition was given by combination treated 46% and 44% for donovani and tropica leishamnia respectively; these results give an indication that the cold atmospheric plasma is a promising treatment of this parasite that threats people all over the world.

  • Fabrication of hesperidin nanoparticles loaded by poly lactic co-Glycolic acid for improved therapeutic efficiency and cytotoxicity
    Saja H. Ali, Ghassan M. Sulaiman, Mohammad M. F. Al-Halbosiy, Majid S. Jabir, and Anaheed H. Hameed

    Artificial Cells, Nanomedicine and Biotechnology, ISSN: 21691401, eISSN: 2169141X, Pages: 378-394, Published: 4 December 2019 Informa UK Limited
    Abstract Hesperidin, as a flavonone, is recognized as promising anti-inflammatory, antioxidant, and anticancer agent. Its poor bioavailability is crucial bottleneck for therapeutic efficacy. To enhance the stability and bioactive potentials, hesperidin -PLGA-Poloxamer 407 was successfully prepared to minimize or overcome problems associated with hesperidin absorption. The characteristics of nanohesperidin were testing by in vitro dissolution study, XRD, FTIR, PSA and SEM. Antioxidant effects of nanohesperidin were studied. The structure–activity relationship analysis with antioxidant pharmacophore has been performed by using density functional theory method and quantum chemical calculations. The structural properties were investigated using Becke three-parameter hybrid exchange and the Lee–Yang–Parr correction functional methods. Nanohesperidin was found to decrease the H2O2 activity–induced DNA instability. Blood compatibility on human erythrocytes was confirmed by haemolytic and in vitro toxicity assessments. The in vitro anticancer activity of nanohesperidin towards MCF-7 cells using various parameters was carried out. The nanohesperidin was found to exert cell growth arrest, activated DNA fragmentation and induced apoptotic cell death through caspase-3 and p53-dependent pathways. These findings showed that nanohesperidin play an important role in its anticancer effects, suggesting might be used for clinical trials and can represent driving formulation for novel chemotherapeutic agents.

  • Phytochemical analysis, cytotoxicity and antioxidant activity of cuckoo pint (Arum maculatum) leaf extract
    Acta Biologica Szegediensis, ISSN: 1588385X, eISSN: 15884082, Pages: 119-124, Published: 2019

  • In vitro cytotoxic activity of some wild plants extracts against RAW264.7 cell line
    Plant Archives, ISSN: 09725210, Pages: 3983-3986, Published: 2019

  • The activity of aqueous extracts of leaves and roots of dandelion on cancer cell lines
    Plant Archives, ISSN: 09725210, Pages: 3933-3936, Published: 2019

  • Complex synthesis of Cis-[Pt(Asc) (NH <inf>3</inf> ) <inf>2</inf> ] and its effect on human breast cancer MCF-7 cell in vitro
    Mohammed A. Al-Dolaymi, Khalid F. Al-Rawi, Firas T. Al-Shamary, and Mohammad M.F. Al-Halbosiy

    Indonesian Journal of Chemistry, ISSN: 14119420, eISSN: 24601578, Pages: 245-253, Published: 2019 Universitas Gadjah Mada
    Bosom malignancy is the most regularly analyzed disease and the imperative reason for growth-related passing among ladies, accounting for 23% of all new tumor cases and 14% of tumor passing's. L-Ascorbic acid, commonly known as vitamin C is well-known in chemistry since long back. It has tremendous medical applications in several diseases. Therefore, in this paper five concentrations of complex cis-[Pt(Asc)(NH3)2] where Asc=L-ascorbic acid derivative on MCF-7 cell line to detect the changes in five cellular parameters (nuclear intensity, mitochondrial membrane potential, valid cell count, cytochrome C, and membrane permeability) after exposure with 24 h are investigated. The results showed that 400 μg/mL has the highest significant effect on the five parameters (nuclear intensity, mitochondrial membrane potential, valid cell count, cytochrome C, and membrane permeability) when compared with Doxorubicin 20 μM (substance used as anti-cancer) which represent the positive control. Also, the 200 μg/mL showed results close to those of the untreated cells which represent the negative control (-ve) with a very few significant differences.

  • The relationship between Chlamydia pneumoniae infection and TNF-α in cardiovascular disease patients
    Hadeel A. Nasser, May K. Ismael and Mohammed M. F. Al. Halbosiy

    Iraqi Journal of Science, ISSN: 00672904, eISSN: 23121637, Pages: 1836-1842, Published: 31 October 2018 University of Baghdad College of Science
    Over the last few years the role of microorganisms in the pathogenesis of atherosclerosis has been widely discussed.  Advance in basic science have established a fundamental role for inflammation immediating all stages of cardiovascular diseases. Chlamydia pneumoniae activates immune cells to produce cytokines such us TNF-α that are important contributor to atherosclerosis. All blood samples were assayed for molecular detection of Chlamydia pneumonia e by using conventional polymerase chain reaction (PCR) relying on16SrRNAand the level of serum TNF-α measured by enzyme linked immunosorbent assay (ELISA).Seventy patients who suffering from CVD (angina, myocardial Infarction and atherosclerosis) aged between 33-86 years have been investigated and compared to twenty of apparently healthy individuals were studies as control group. Twenty six sample (37.14) %detected positive results for Chlamydia pneumonia e by PCR techniques in patient group, while all control group were negative, furthermore current study revealed a highly significant elevation (p<0.01) in the mean level of TNF-α in sera of patients with CVD compared to control group. Also there were considerable differences in the level of TNF-α between Chlamydia pneumonia e positive and negative within the patient group. The present study concludes there is a significant proportion among patients who infected with C. Pneumoniae and these bacteria play an essential role in the pathogenesis of CVD through stimulation of the inflammatory response.

  • Genetic polymorphism of ITGA2 gene and the risk of heart attack and stroke in Al-Anbar population/Iraq
    Journal of Pharmaceutical Sciences and Research, eISSN: 09751459, Pages: 2305-2308, Published: September 2018

  • The anti-fertility and cytotoxicity effects of cyproterone acetate and phenolic extract of hibiscusrosa sinensis linn flowers in male albino rats
    H.M. Al-Saily, F.N. Al-Hady, and M.M. Al-halbosiy

    Indian Journal of Public Health Research and Development, ISSN: 09760245, eISSN: 09765506, Pages: 177-181, Published: July 2018 Diva Enterprises Private Limited

  • Cytotoxic and apoptotic effects of phenolic extract of hibiscus rosa sinensis linn flowers against cancer cells and normal cells
    H.M. Al-Saily, M.M. Al-halbosiy, and F.N. Al-Hady

    Indian Journal of Public Health Research and Development, ISSN: 09760245, eISSN: 09765506, Pages: 188-192, Published: July 2018 Diva Enterprises Private Limited

  • Cytotoxic effects of new synthesis heterocyclic derivatives of Amoxicillin on some cancer cell lines
    M S Al-Rawi, D F Hussei, A F Al-Taie, M M Al-Halbosiy, and B A Hameed

    Journal of Physics: Conference Series, ISSN: 17426588, eISSN: 17426596, Volume: 1003, Published: 25 May 2018 IOP Publishing

  • Synthesis and characterization of small-sized gold nanoparticles coated by bovine serum albumin (BSA) for cancer photothermal therapy
    Selma M.H. AL-Jawad, Ali A. Taha, Mohammad M.F. Al-Halbosiy, and Lamyaa F.A. AL-Barram

    Photodiagnosis and Photodynamic Therapy, ISSN: 15721000, eISSN: 18731597, Pages: 201-210, Published: March 2018 Elsevier BV
    In the present study, small gold nanoparticles <5 nm coated with natural protein Bovine Serum Albumin (BSA) was synthesized and characterized using UV-vis spectrophotometer, Dynamic Light Scattering (DLS), Transmission Electron Microscopy (TEM), zeta potential and scanning electron microscopy (SEM). Three types of cancer cell lines; Rhabdomyosarcoma (RD), Murine fibroblast (L20B) and RAW 264.7 monocyte-macrophage (MQ) were tested and treated by photothermal strategy, in vitro, by conjugating BSA-AuNPs complex of (0.125, 0.25, 0.5 and 1 mg/ml) concentrations with continuous low power laser irradiation, green (532 nm) and near-infrared (NIR) (800 nm) at 0.5, 1, 2 and 3 min, separately. Cytotoxicity effect was determined by MTT assay. The vital impact of photothermal technique has investigated at 1 mg/ml and 3 min irradiation period as identified in RD cell line in comparison with other types; where cytotoxicity more than 74% was reached. Prominent results were demonstrated in the green and NIR region by pH -induced aggregation effect of small nanoparticles inside the cancer cells, which make the small-sized BSA-AuNPs are promising agents for cancer photothermal therapy.

  • Biological activity of levan produced from rhizospheric soil bacterium brachybacterium phenoliresistens kx139300
    Baghdad Science Journal

    Baghdad Science Journal, ISSN: 20788665, eISSN: 24117986, Pages: 238-243, Published: 2018 College of Science for Women
    The electric quadrupole moments for some scandium isotopes (41, 43, 44, 45, 46, 47Sc) have been calculated using the shell model in the proton-neutron formalism. Excitations out of major shell model space were taken into account through a microscopic theory which is called core polarization effectives. The set of effective charges adopted in the theoretical calculations emerging about the core polarization effect. NushellX@MSU code was used to calculate one body density matrix (OBDM). The simple harmonic oscillator potential has been used to generate the single particle matrix elements. Our theoretical calculations for the quadrupole moments used the two types of effective interactions to obtain the best interaction compared with the experimental data. The theoretical results of the quadrupole moments for some scandium isotopes performed with FPD6 interaction and Bohr-Mottelson effective charge agree with experimental values.

Publications

●Ad'hiah,A.H.;Al-Halbosiy,M.M.F. & Al-Jumaily,R.M.Kh (2007). " Modulating the Hematological and cytogenetic Effects of Mitomycin C by Aqueous Extract of Nut Grass(Cyperus rotundus L.).J.Biotechnology Research Center 1(1):43-51.
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●Al-Halbosiy,M.M.F.;Al-JumaiJly,R.M.Kh.&.Ad'hiah,A.H. (2007) ." The Mutagenic Effects of Mitomycin C by Aqueous Modulating Extract of Alhagi graecorum" Ibn Al-Hatham ,J.Pur&Appl.Sci 20(2):1-7.
● Al-Halbosiy,M.M.F.; Sulaiman,G.M. & Al-JumaiJly,R.M.Kh. (2008)."The modulator effect of Iraqi propolis Extract on Mitomycin C Induced micronucleus formation in albino male mice". faculty, Med.J.Bagdad, 50(1):77-82.
● Al-Halbosiy,M.M.F. (2009)." Modulating the Mutagenic Effects of Mitomycin C by Aqueous Extract of Lentil (Lens culinars)" J.Biotechnology Research Center, 3(1):37-43.
●Al-Jumaily,R.M.Kh &; Ad'hiah,A.H. & Al-Halbosiy,M.M.F. (2010)."Evaluation of some haematological and cytogenetic effects of Ammi majus seed aqueous extract in albino male mice". Journal of Biotechnology Research Center, (special edition) Vol.4 No.1
●Hatem Tallima, Mohammad Farhan Al-Halbosiy, Rashika El Ridi(2011). Enzymatic activity and immunolocalization of Schistosoma mansoni and Schistosoma haematobium neutral
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sphingomyelinase. Molecular & Biochemical Parasitology (178): 23–28.
●Rashika El Ridi, Hatem Tallima, Mohamed Salah, Marwa Aboueldahab, Omar M. Fahmy,Mohammad Farhan Al-Halbosiy, Soheir S. Mahmoud (2012). Efficacy and mechanism of action of arachidonic acid in the treatment of hamsters infected with Schistosoma mansoni or Schistosoma haematobium. International Journal of Antimicrobial Agents (39): 232– 239.
● Mohammed M. F. Al-Halbosiy, Rakad M. Kh. Al- Jumaily, Fadhel M. Lafta & Hussam M. Hassan (2013). Inhibitory Effect of Camel Urine on Neoplastic and Transformed Cell Lines. International Journal for Sciences and Technology Vol. 8, No.2, 31-35.
●Rakad M. Kh. Al- Jumaily, Laith M.J. Al-Shamma, Mohammad M.F. Al-Halbosiy (2013). The ability of rapeseed (brassica napus I.) Seeds oil in inhibiting cell line growth in vitro. Iraqi Journal of Biotechnology, Vol.12, No.1, 106-113.
● Rakad M. Kh. Al- Jumaily, Nawal MJ Al- Shamma, Mohammad M. Al-Halbosiy ,Laith M.J. Al-Shamma (2014). Anticancer Activity of Sunflower (Helianthus annuns L.) Seeds oil against cell line. Iraqi Journal of Science Vol. 54, supplement No.4, 1003-1009.
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●Zainab Y. Mohammed, Saad M. Nada, Mohammad M. Al-Halbosiy, Shaimaa Y.Abdulfattah , Baraa Abdul-Hameed (2014). Cytotoxic effects of Ammi visnaga volatile oil on some cancer cell lines. Journal of Biotechnology Research Center (special edition). Vol.8 No.1, 5-7.
●Mohammad M. F. Al-Halbosiy, Farah Th. Abdulla, Shimaa Y. Abdulfattah, Sabah M. Hussein , Baraa A. Abdul Hameed , Wathiq Q. Shaker and Fathel A.Hasan (2014).Cytogenetic and hormonal study for sample of men infertile in Iraq. International Journal for Sciences and Technology, Vol. 9, No.1: 62-65.
● Abeer M. Badr, Mohammed M. F. Al-Halbosiy, Rashika El Ridi. (2015). Differential immune responses toexcretory─secretoryantigens of lung-stage larvae of Schistosoma mansoniin mice and rats. The Journal of Basic & Applied Zoology. 69, 26–33.
● Mohammed Adel Nouri, Mohammed M. F. Al-Halbosiy, Batol Imran Dheeb, Abdulkareem Jasim Hashim. (2015). Cytotoxicity and Genotoxicity of Gliotoxin on human lymphocytes in vitro. Journal of King Saud University – Science.
● Mohammad M. F. Al-Halbosiy, Rakad M. Kh. Al-Jumaily, Fadhel M . Lafta. (2015). The Exposure Effect of Water Pipe Smoke (WPS) on the Total Count leukocyte, Mitotic Index, Micronucleus Formation and Chromosome Aberration in Albino Male Mice. Journal of Biotechnology Research Center, Vol. 9, No.2: 89-93.
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● Rawaa N. Abdallah1, Raghad K. Allihaibi, Mohammad M.F. Al-Halbosiy and Ali A. Taha (2016). Preparation of Nanoliposomes by Size Exclusion Chromatography to Entrap Soluble Antigens from Leishmania donovani. Iraq Journal of Science (Vol. 57, No.2A, : 814-823).
● Niran A.H. Al-Ogaili, Mohammed M.F. Al-Halbosiy, Mahmoud Zayanal Mohammed, Zainab Al-Hawraa Mohammed, Afyaa Diyaa Rushk. (2017). IN VITRO INVESTIGATION OF ANTIBACTERIAL AND ANTILEISHMANIAL ACTIVITIES OF GUM-RESIN OF BOSWELLIA SERRATA USING (0.5%) DMSO SOLUTION AS AN ALTERNATIVE SOLVENT FOR EXTRACTION. World Journal of Pharmacy and Pharmaceutical Sciences, 6(9): 190-199.
● Hujran Abed Al-raheem Abed, Huda F Hasan and Mohammad MF Al-Halbosiy. (2017). Comparative effect between Mesenchymal Stem Cells (MSCs) and Clomiphine citrate on induced premature ovarian failure (POF) in mice. Journal of Entomology and Zoology Studies 2017; 5(5): 955-963. ● Huda F. Hasan, Esraa M. Krair, Mohammad M.F.Al-Halbosiy. (2017). Evaluating anti-anemic effect of Mesenchymal Stem Cells and Oxymetholone on aplastic anemia induced in mice.
● Rajwa Hasen Essa, Mohammad Mahmood F. Al-Halbosiy, Sundus Hameed Ahmed. (2017). Evaluation, Antioxidant, Antimitotic and Anticancer Activity of Iron Nanoparticles Prepared by Using Water Extract of Vitis vinifera L. Leaves. Journal of Advanced Laboratory Research in Biology, 8 (3) :67-73.
●Afnan R. A. Al-Tekreeti, Mohammad M. F. Al-Halbosiy, Batol I. Dheeb, Abdulkareem J. Hashim, Anaam F. H. Al-Zuhairi, Farooq
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I. Mohammad. (2018). Molecular identification of clinical Candida isolates by simple and randomly amplified polymorphic DNA-PCR. Arabian Journal for Science and Engineering 43: 163-170.
● Selma M.H. AL-Jawad, Ali A. Taha, Mohammad M.F. Al-Halbosiy, Lamyaa F.A. AL-Barram. (2018). Synthesis and characterization of small-sized gold nanoparticles coated by bovine serum albumin (BSA) for cancer photothermal therapy. Photodiagnosis and Photodynamic Therapy 21: 201–210.
● Huda F. Hasan, Esraa M. Krair, Mohammad M.F.Al-Halbosiy. Evaluating anti-anemic effect of Mesenchymal Stem Cells and Oxymetholone on aplastic anemia induced in mice. (2017).