Alexandre Prola

@unige.ch

Faculty of Medicine, Department of Cell Physiology and Metabolism
University of Geneva

Alexandre Prola


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https://researchid.co/alexandreprola
2553

Scholar Citations

20

Scholar h-index

24

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • CtBP1 sustains activity-dependent muscle properties and dampens synaptic, contractile and metabolic changes triggered by denervation
    O Cattaneo, G Lopez, J Rajendran, F Chabry, N Liaudet, S Startchik, ...
    Skeletal Muscle , 2026
    2026
  • Transient hypoxia followed by progressive reoxygenation is required for muscle repair
    M Quétin, A Der Vartanian, C Dubois, J Berthier, M Ledoux, S Michineau, ...
    EMBO reports, 1-21 , 2026
    2026
  • Skeletal muscle fibre type determines mitochondrial and metabolic responses to hypoxia and pulmonary inflammation
    A Gavrielatos, C Cottet-Rousselle, N Brocker, C Tellier, A Achouri, A Prola, ...
    bioRxiv, 2025.10. 06.680623 , 2025
    2025
  • CtBP1 coordinates synaptic, metabolic and contractile changes induced by denervation in skeletal muscle
    O Cattaneo, G Lopez, J Rajendran, F Chabry, A Prola, N Liaudet, ...
    bioRxiv, 2025.03. 29.646097 , 2025
    2025
  • Cardiolipin deficiency disrupts electron transport chain to drive steatohepatitis
    MJ Brothwell, G Cao, JA Maschek, AM Poss, AD Peterlin, L Wang, ...
    bioRxiv, 2024.10. 10.617517 , 2025
    2025
    Citations: 6
  • Cardiolipin deficiency disrupts CoQ-complex III interface in steatohepatitis
    MJ Brothwell, G Cao, JA Maschek, AM Poss, AD Peterlin, L Wang, ...
    2025
  • Cardiolipin deficiency disrupts CoQ redox state and induces steatohepatitis
    MJ Brothwell, G Cao, JA Maschek, AM Poss, AD Peterlin, L Wang, ...
    bioRxiv, 2024.10. 10.617517 , 2024
    2024
  • Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of …
    A Tollance, A Prola, D Michel, A Bouche, A Turzi, D Hannouche, S Berndt, ...
    Stem Cell Reviews and Reports 20 (7), 1981-1994 , 2024
    2024
    Citations: 3
  • PINK1 deficiency alters muscle stem cell fate decision and muscle regenerative capacity
    G Cairns, M Thumiah-Mootoo, MR Abbasi, M Gourlay, J Racine, ...
    Stem Cell Reports 19 (5), 673-688 , 2024
    2024
    Citations: 19
  • mTORC1-dependent SOCE activity regulates synaptic gene expression and muscle response to denervation
    A Prola, O Dupont, J Rajendran, F Chabry, S Koenig, M Frieden, ...
    bioRxiv, 2024.04. 01.587665 , 2024
    2024
  • Identification of a muscle-specific isoform of VMA21 as a potent actor in X-linked myopathy with excessive autophagy pathogenesis
    I Cocchiararo, O Cattaneo, J Rajendran, F Chabry, M Cornut, H Soldati, ...
    Human Molecular Genetics 32 (24), 3374-3389 , 2023
    2023
    Citations: 6
  • Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease
    N Khadhraoui, A Prola, A Vandestienne, J Blondelle, L Guillaud, ...
    Molecular metabolism 69, 101677 , 2023
    2023
    Citations: 5
  • Cardiolipin alterations during obesity: exploring therapeutic opportunities
    A Prola, F Pilot-Storck
    Biology 11 (11), 1638 , 2022
    2022
    Citations: 19
  • Metabolic regulation of adult muscle stem cells
    A Prola, L Neff, O Dorchies, V Allamand, F Relaix, P Castets
    Myologie 2022 , 2022
    2022
  • Punicalagin targets atherosclerosis: gene expression profiling of THP-1 macrophages treated with punicalagin and molecular docking
    E Huwait, S Almowallad, R Al-Massabi, S Saddeek, K Gauthaman, ...
    Current Issues in Molecular Biology 44 (5), 2153-2166 , 2022
    2022
    Citations: 14
  • Thymoquinone (TQ) inhibits inflammation and migration of THP-1 macrophages: mechanistic insights into the prevention of atherosclerosis using in-vitro and in-silico analysis
    E Huwait, N Al-Gharawi, MA Al-Ghamdi, M Gari, A Prola, ...
    Current Issues in Molecular Biology 44 (4), 120 , 2022
    2022
    Citations: 7
  • Isolation and Phospholipid Enrichment of Muscle Mitochondria and Mitoplasts
    A Prola, A Vandestienne, N Baroudi, F Joubert, L Tiret, F Pilot-Storck
    Bio-protocol 11 (20), e4201-e4201 , 2021
    2021
    Citations: 1
  • Endurance is improved in female rats after living high-training high despite alterations in skeletal muscle
    A Malgoyre, A Prola, A Meunier, R Chapot, B Serrurier, N Koulmann, ...
    Frontiers in Sports and Active Living 3, 663857 , 2021
    2021
    Citations: 9
  • Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming
    J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier, Z Koumaiha, K Kefi, ...
    Cell metabolism 33 (2), 283-299. e9 , 2021
    2021
    Citations: 319
  • Perspectives on skeletal muscle stem cells
    F Relaix, M Bencze, MJ Borok, A Der Vartanian, F Gattazzo, ...
    Nature communications 12 (1), 692 , 2021
    2021
    Citations: 421

MOST CITED SCHOLAR PUBLICATIONS

  • Perspectives on skeletal muscle stem cells
    F Relaix, M Bencze, MJ Borok, A Der Vartanian, F Gattazzo, ...
    Nature communications 12 (1), 692 , 2021
    2021
    Citations: 421
  • Platelets facilitate the wound-healing capability of mesenchymal stem cells by mitochondrial transfer and metabolic reprogramming
    J Levoux, A Prola, P Lafuste, M Gervais, N Chevallier, Z Koumaiha, K Kefi, ...
    Cell metabolism 33 (2), 283-299. e9 , 2021
    2021
    Citations: 319
  • SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation
    A Prola, J Pires Da Silva, A Guilbert, L Lecru, J Piquereau, M Ribeiro, ...
    Cell Death & Differentiation 24 (2), 343-356 , 2017
    2017
    Citations: 246
  • Downregulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
    J Piquereau, F Caffin, M Novotova, A Prola, A Garnier, P Mateo, D Fortin, ...
    Cardiovascular Research , 2012
    2012
    Citations: 231
  • Hypothalamic AgRP‐neurons control peripheral substrate utilization and nutrient partitioning
    A Joly‐Amado, RGP Denis, J Castel, A Lacombe, C Cansell, C Rouch, ...
    The EMBO journal 31 (22), 4276-4288 , 2012
    2012
    Citations: 148
  • Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway
    M Boussabbeh, I Ben Salem, A Prola, A Guilbert, H Bacha, S Abid-Essefi, ...
    Toxicological sciences 144 (2), 328-337 , 2015
    2015
    Citations: 129
  • Necroptosis mediates myofibre death in dystrophin-deficient mice
    JE Morgan, A Prola, V Mariot, V Pini, J Meng, C Hourde, J Dumonceaux, ...
    Nature communications 9 (1), 3655 , 2018
    2018
    Citations: 123
  • Mitochondrial physiology
    C Gourlay
    bioenergetic communications 1 (1), 1-44 , 2020
    2020
    Citations: 122
  • Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2
    C Gallerne, A Prola, C Lemaire
    Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (6), 1356-1366 , 2013
    2013
    Citations: 108
  • Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress
    IB Salem, A Prola, M Boussabbeh, A Guilbert, H Bacha, S Abid-Essefi, ...
    Cell Stress and Chaperones 20 (6), 927-938 , 2015
    2015
    Citations: 85
  • Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy
    N Diguet, Y Mallat, R Ladouce, G Clodic, A Prola, E Tritsch, J Blanc, ...
    Journal of Biological Chemistry 286 (40), 35007-35019 , 2011
    2011
    Citations: 69
  • HACD1 , a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth
    J Blondelle, Y Ohno, V Gache, S Guyot, S Storck, N Blanchard-Gutton, ...
    Journal of molecular cell biology 7 (5), 429-440 , 2015
    2015
    Citations: 64
  • Endoplasmic reticulum stress induces cardiac dysfunction through architectural modifications and alteration of mitochondrial function in cardiomyocytes
    A Prola, Z Nichtova, J Pires Da Silva, J Piquereau, K Monceaux, ...
    Cardiovascular Research 115 (2), 328-342 , 2019
    2019
    Citations: 59
  • Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1‐deficient mice
    F Caffin, A Prola, J Piquereau, M Novotova, DJ David, A Garnier, D Fortin, ...
    The Journal of physiology 591 (23), 6017-6037 , 2013
    2013
    Citations: 59
  • Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle
    A Prola, J Blondelle, A Vandestienne, J Piquereau, RGP Denis, S Guyot, ...
    Science advances 7 (1), eabd6322 , 2021
    2021
    Citations: 57
  • Crocin and quercetin prevent PAT‐induced apoptosis in mammalian cells: Involvement of ROS‐mediated ER stress pathway
    M Boussabbeh, A Prola, I Ben Salem, A Guilbert, H Bacha, C Lemaire, ...
    Environmental Toxicology 31 (12), 1851-1858 , 2016
    2016
    Citations: 55
  • Activation of ER stress and apoptosis by α-and β-zearalenol in HCT116 cells, protective role of Quercetin
    IB Salem, A Prola, M Boussabbeh, A Guilbert, H Bacha, C Lemaire, ...
    Neurotoxicology 53, 334-342 , 2016
    2016
    Citations: 47
  • Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus
    L Delavallée, N Mathiah, L Cabon, A Mazeraud, MN Brunelle-Navas, ...
    Molecular metabolism 40, 101027 , 2020
    2020
    Citations: 42
  • Crocin protects human embryonic kidney cells (HEK293) from α-and β-zearalenol-induced ER stress and apoptosis
    I Ben Salem, M Boussabbeh, A Prola, A Guilbert, H Bacha, C Lemaire, ...
    Environmental Science and Pollution Research 23 (15), 15504-15514 , 2016
    2016
    Citations: 30
  • Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress
    A Salah, C Bouaziz, A Prola, J Pires Da Silva, H Bacha, S Abid-Essefi, ...
    Journal of Toxicology and Environmental Health, Part A 80 (23-24), 1230-1241 , 2017
    2017
    Citations: 28