Klingbeil

@ipen.br

Centro de Tecnologia das Radiações
Instituto de Pesquisas Energéticas e Nucleares IPEN/CNEN-SP

EDUCATION

Dental School: Universidade Católica de Campinas (PUCC)
Master Degree: Centro de Tecnologia das Radiações; Instituo de Pesquisas Energéticas e Nucleares IPEN/CNEN-SP
PhD: Faculdade de Odontologia - FOUSP; Universidade de São Paulo - USP.

RESEARCH INTERESTS

Cell culture, Tissue Engineering, Primay culture, Cell biology, Oral Pathology, Periodontology, Biocompatibility, Citotoxicicity tests, squamous cell carcinoma, Cell proliferation, Fibroblasts, Mesenchymal cells, Scaffolds biocompatibility.

273

Scholar Citations

9

Scholar h-index

9

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • A biological study of gelatin-PVA based scaffold functionalized with albumin for biomedical purposes
    JO VARCA, F KLINGBEIL, KM NOGUEIRA, CS LIMA, CC da CRUZ, ...
    2023

  • Development of collagen/nanohydroxyapatite scaffolds containing plant extract intended for bone regeneration
    CF Garcia, CA Marangon, LC Massimino, MFG Klingbeil, VCA Martins, ...
    Materials Science and Engineering: C 123, 111955 2021

  • Use of collagen and auricular cartilage in bioengineering: Scaffolds for tissue regeneration
    LC Massimino, V da Conceio Amaro Martins, VAS Vulcani, ...
    Cell and Tissue Banking, 1-12 2020

  • Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Maytenus ilicifolia Roots Associated with
    C Hernandes, L Miguita, RO de Sales, EP Silva, POR Mendona, ...
    Molecules 25 (3), 760 2020

  • Candida albicans-Cell Interactions Activate Innate Immune Defense in Human Palate Epithelial Primary Cells via Nitric Oxide (NO) and β-Defensin 2 (hBD-2)
    AR Casaroto, RA da Silva, S Salmeron, MLR Rezende, TJ Dionsio, ...
    Cells 8 (7), 707 2019

  • Development of gelatin based scaffold by gamma radiation for application as platelet rich plasma support for wound treatment
    JPRO VARCA, A Ferrari, DR Pignata, SK Guazzelli, MFG KLINGBEIL, ...
    Regenerative Research 2019

  • Avoiding chemotherapy resistance in squamous cell carcinomas: anticancer activities of terpenoids and their impact on the regulation of microRNAs
    C Hernandes, B Silva, MFG Klingbeil, MB Mathor, AMS Pereira, ...
    Cancer Research 77 (13_Supplement), 5456-5456 2017

  • Irradiated Murine Fibroblast As Feeder Layer Used in Human Ceel Culture
    TL ALMEIDA, MFG KLINGBEIL, D YOSHITO, MR HERSON, P CAPRONI, ...
    2017

  • Cultivo de fibroblastos murinos 3T3-J2 e posterior irradiao para utilizao como camada de sustentao" Feeder Layer" no cultivo de queratincitos bucais humanos
    TL ALMEIDA, MFG KLINGBEIL, MB MATHOR
    2016

  • Anlise dos resultados obtidos com o teste:" Eficiencia de Formao de Colnias (CFE)", aplicado no cultivo de queratincitos bucais humanos
    D Yoshito, MFG Klingbeil, MB MATHOR, PIDEB DE INICIAO, ...
    2016

  • Citotoxicidade do Viscum album L. em clulas de carcinoma epidermoide da cavidade bucal. Cytotoxicity of mistletoe (Viscum album L.) in oral squamous cell carcinoma.
    MFG KLINGBEIL, LR SARDINHA, MB MATHOR, DS PINTO JR
    Editora Antroposfica 2016

  • Comparison between interdental brush and dental floss controlling interproximal biofilm in teeth and implants
    M Luz, MFG Klingbeil, PSG Henriques, HR Lewgoy
    Dent. Health Curr. Res 2 2016

  • Citotoxicidade do Viscum album L. em clulas de carcinoma epidermoide da cavidade bucal
    MFG Klingbeil, LR Sardinha, MB Mathor, DS Pinto Jnior
    Arte Med. Ampl, 8-13 2016

  • c-Jun, pc-Jun, and p27 are differently expressed in oral leukoplakias in smokers and never-smokers
    JS Lima, L Correa, MFG Klingbeil, SCOM de Sousa
    Oral surgery, oral medicine, oral pathology and oral radiology 121 (1), 73-80 2016

  • Cncer e doena periodontal
    MFG Klingbeil, AEA Rodrigues, PSG Henriques
    Perionews, 34-41 2015

  • High-throughput sequencing of small RNA transcriptomes reveals critical biological features targeted by microRNAs in cell models used for squamous cell cancer research
    P Severino, LS Oliveira, N Torres, FM Andreghetto, ...
    BMC genomics 14, 1-15 2013

  • Cytotoxic effects of mistletoe (Viscum album L.) in head and neck squamous cell carcinoma cell lines
    MFG KLINGBEIL, FCA XAVIER, LR SARDINHA, P Severino, ...
    2013

  • MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation. BMC Cancer (Online), v
    P EVERINO, H BRGGEMANN, F ANDREGHETTO, C CAMPS, ...
    2013

  • MicroRNAs and cell proliferation in head and neck squamous cell carcinoma
    FM Andreghetto, MFG Klingbeil, RM Soares, DS Pinto-Junior, MB Mathor, ...
    BMC Proceedings 7, 1-1 2013

  • Epithelium: Composition, Functions and Pathology
    MFG KLINGBEIL, FS GIUDICE, FF SPERANDIO, DS PINTO JR
    ENDOTHELIUM AND EPITHELIUM Composition, Functions and Pathology 1, 1-33 2012

MOST CITED SCHOLAR PUBLICATIONS

  • Comparison of two cellular harvesting methods for primary human oral culture of keratinocytes
    MFG KLINGBEIL, MR HERSON, EB CRISTO, DS PINTO JR, D YOSHITO, ...
    2009 10, 197-204
    Citations: 51

  • Cytotoxic effects of mistletoe (Viscum album L.) in head and neck squamous cell carcinoma cell lines
    MFG KLINGBEIL, FCA XAVIER, LR SARDINHA, P Severino, ...
    2013
    Citations: 46

  • Development of collagen/nanohydroxyapatite scaffolds containing plant extract intended for bone regeneration
    CF Garcia, CA Marangon, LC Massimino, MFG Klingbeil, VCA Martins, ...
    Materials Science and Engineering: C 123, 111955 2021
    Citations: 34

  • Anticancer Activities of the Quinone-Methide Triterpenes Maytenin and 22-β-hydroxymaytenin Obtained from Cultivated Maytenus ilicifolia Roots Associated with
    C Hernandes, L Miguita, RO de Sales, EP Silva, POR Mendona, ...
    Molecules 25 (3), 760 2020
    Citations: 22

  • Candida albicans-Cell Interactions Activate Innate Immune Defense in Human Palate Epithelial Primary Cells via Nitric Oxide (NO) and β-Defensin 2 (hBD-2)
    AR Casaroto, RA da Silva, S Salmeron, MLR Rezende, TJ Dionsio, ...
    Cells 8 (7), 707 2019
    Citations: 21

  • Use of collagen and auricular cartilage in bioengineering: Scaffolds for tissue regeneration
    LC Massimino, V da Conceio Amaro Martins, VAS Vulcani, ...
    Cell and Tissue Banking, 1-12 2020
    Citations: 20

  • High-throughput sequencing of small RNA transcriptomes reveals critical biological features targeted by microRNAs in cell models used for squamous cell cancer research
    P Severino, LS Oliveira, N Torres, FM Andreghetto, ...
    BMC genomics 14, 1-15 2013
    Citations: 19

  • Comparison between interdental brush and dental floss controlling interproximal biofilm in teeth and implants
    M Luz, MFG Klingbeil, PSG Henriques, HR Lewgoy
    Dent. Health Curr. Res 2 2016
    Citations: 13

  • c-Jun, pc-Jun, and p27 are differently expressed in oral leukoplakias in smokers and never-smokers
    JS Lima, L Correa, MFG Klingbeil, SCOM de Sousa
    Oral surgery, oral medicine, oral pathology and oral radiology 121 (1), 73-80 2016
    Citations: 10

  • Multiple myeloma with primary manifestation in mandibular area
    PS da Silva Santos, MFG KLINGBEIL, AC ABRAHO, M Gallottini, ...
    2012
    Citations: 8

  • Evaluation of microRNA expression in head and neck squamous cell carcinoma cell lines and in primary culture of oral keratinocytes
    FM Andreghetto, MFG Klingbeil, RM Soares, R Sitnik, DS Pinto Junior, ...
    Einstein (So Paulo) 9, 442-448 2011
    Citations: 8

  • Oral Koilocytic Dysplasia: long-term clinical control. A case report
    MFG KLINGBEIL, MDM Lima, M MAGALHES, DS PINTO JR, ...
    2012
    Citations: 7

  • IS IT SAFE TO UTILIZE IN VITRO RECONSTITUTED HUMAN ORAL EPITHELIUM? AN ONCOGENETIC PATHWAY STUDY
    MFG KLINGBEIL, MB MATHOR, FS GIUDICE, D YOSHITO, DS PINTO JR
    2010
    Citations: 5

  • Comparao de dois mtodos de obteno celular para cultura primaria de queratincitos bucais humanos
    MFG Klingbeil
    Dissertao de Mestrado em Cincias na rea de Tecnologia Nuclear-Aplicaes 2006
    Citations: 3

  • Irradiated Murine Fibroblast As Feeder Layer Used in Human Ceel Culture
    TL ALMEIDA, MFG KLINGBEIL, D YOSHITO, MR HERSON, P CAPRONI, ...
    2017
    Citations: 2

  • MicroRNAs and cell proliferation in head and neck squamous cell carcinoma
    FM Andreghetto, MFG Klingbeil, RM Soares, DS Pinto-Junior, MB Mathor, ...
    BMC Proceedings 7, 1-1 2013
    Citations: 1

  • Avaliao da expresso de microRNAs em linhagens celulares de carcinoma epidermoide de cabea e pescoo e em cultura primria de queratincitos orais
    FM Andreghetto, MFG Klingbeil, RM Soares, R Sitnik, DS Pinto Junior, ...
    einstein (So Paulo) 9, 442-448 2011
    Citations: 1

  • Adenomatoid odontogenic tumour: A case report
    MFG KLINGBEIL, MAP Albuquerque, FS GIUDICE, MGP Cavalcanti, ...
    2011
    Citations: 1

  • The comparison of two methods to obtain human oral keratinocytes in primary culture
    MFG Klingbeil
    2006
    Citations: 1

Publications

LIMA, JOELMA SOUSA ; CORREA, LUCIANA ; GUARIZO KLINGBEIL, MARIA FÁTIMA ; ORSINI MACHADO DE SOUSA, SUZANA C. . c-Jun, pc-Jun, and p27 are differently expressed in oral leukoplakias in smokers and never-smokers. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, v. 121, p. 73-80, 2016.

KLINGBEIL, M.F.G.; RODRIGUES, A. E. A. ; HENRIQUES, P. S. G. . Câncer e Doença Periodontal. Perionews (São Paulo), v. 9, p. 34-41-41, 2015.

KLINGBEIL, M.F.G.; XAVIER, FCA ; SARDINHA, LR ; S, P ; MATHOR, M. B. ; Rodrigues, RV ; PINTO JR, D. S. . Cytotoxic effects of mistletoe (Viscum album L.) in head and neck squamous cell carcinoma cell lines. Oncology Reports, p. 2316-2322, 2013.
Citações:8|6

SEVERINO, PATRICIA ; OLIVEIRA, LILIANE ; TORRES, NATALIA ; ANDREGHETTO, FLAVIA ; DE FATIMA GUARIZO KLINGBEIL, MARIA ; MOYSES, RAQUEL ; WÜNSCH-FILHO, VICTOR ; NUNES, FABIO ; MATHOR, MONICA ; PASCHOAL, ALEXANDRE ; DURHAM, ALAN . High-throughput sequencing of small RNA transcriptomes reveals critical biological features targeted by microRNAs in cell models used for squamous cell cancer research. BMC Genomics, v. 14, p. 735, 2013.
Citações:7|8

SEVERINO, PATRICIA ; BRÜGGEMANN, HOLGER ; ANDREGHETTO, FLAVIA ; CAMPS, CARME ; KLINGBEIL, MARIA DE FATIMA ; DE PEREIRA, WELBERT ; SOARES, RENATA ; MOYSES, RAQUEL ; WÜNSCH-FILHO, VICTOR ; MATHOR, MONICA ; NUNES, FABIO ; RAGOUSSIS, JIANNIS ; TAJARA, ELOIZA . MicroRNA expression profile in head and neck cancer: HOX-cluster embedded microRNA-196a and microRNA-10b dysregulation implicated in cell proliferation. BMC Cancer (Online), v. 13, p. 533, 2013.
Citações:24|17

da Silva Santos, P.S. ; KLINGBEIL, M.F.G. ; ABRAHÃO, A.C. ; Gallottini, M. ; de Sousa, S.C.O.M. . Multiple myeloma with primary manifestation in mandibular area. Oral Surgery (Print), v. 5, p. 26-29, 2012.
Citações:3

KLINGBEIL, M.F.G.; Lima, MDM ; MAGALHÃES, M.H.C.G. ; PINTO JR, D. S. ; Lemos Jr., CA . Oral Koilocytic Dysplasia: long-term clinical control. A case report. Minerva Stomatologica (Testo stampato), v. 61, p. 288-293, 2012.
Citações:3

KLINGBEIL, M.F.G.; Albuquerque, MAP ; GIUDICE, F. S. ; Cavalcanti, MGP ; PINTO JR, D. S. . ?Adenomatoid odontogenic tumour: A case report?. Pediatric Dental Journal, v. 21, p. 1-6, 2011.

Andreghetto, FM ; KLINGBEIL, M.F.G. ; SOARES, R ; PINTO JR, D. S. ; MATHOR, M. B. ; Nunes, FD ; S, P . Evaluation of microRNA expression in head and neck squamous cell carcinoma cell lines and in primary. Einstein (São Paulo), v. 9, p. 442-448, 2011.

KLINGBEIL, M.F.G.; MATHOR, M. B. ; GIUDICE, FS ; YOSHITO, D. ; PINTO JR, D. S. . IS IT SAFE TO UTILIZE IN VITRO RECONSTITUTED HUMAN ORAL EPITHELIUM? AN ONCOGENETIC PATHWAY STUDY. Cell and Tissue Banking (Dordrecht. Online), v. 00, p. PMID:20730566[P-00, 2010.
Citações:3|2

KLINGBEIL, M.F.G.; HERSON, M. R. ; CRISTO, E.B. ; PINTO JR, D. S. ; YOSHITO, D. ; MATHOR, M. B. . Comparison of two cellular harvesting methods for primary human oral culture of keratinocytes. Cell and Tissue Banking (Dordrecht. Online), v. 10, p. 197-204, 2009.
Citações:6|13