Filippo Maria Cogiamanian

Scopus Publications

Clinical usability of telephone-based cognitive screening tests in Parkinson's disease
Angelica De Sandi, Edoardo Nicolò Aiello, Federica Verardo, Denise Mellace, Angelica Marfoli, et al.
Journal of Parkinson S Disease, 2026
Background Accessible screening tools are crucial for the early detection of cognitive impairment in Parkinson's disease (PD), especially in contexts where in-person assessments are not feasible. Objective To assess the clinical usability of telephone-based cognitive screening (TBCS) tools in PD patients. Methods Forty-two non-demented PD individuals and N = 103 healthy controls (HCs) underwent a TBCS battery including the Telephone Interview for Cognitive Status (TICS), the Telephone-based Frontal Assessment Battery (t-FAB) and sub-tests from the Telephone-based Verbal Fluency Battery (t-VFB) and Telephone Language Screener (TLS). PD individuals were also administered the Montreal Cognitive Assessment (MoCA) in person and assessed for behavior and cognitive-driven functional independence via caregiver-report questionnaires administered over the telephone (Neuropsychiatric Inventory, NPI and Amsterdam IADL Questionnaire – 30-item version, A-IADL-Q-30, respectively). Correlations were run to test the construct and ecological validity of TBCS tests in PD individuals; ROC analyses were run to test the capability of TBCS tests to discriminate PD individuals from HCs and PD individuals with a defective MoCA from those performing normally (PD-MCI vs. PD-CN). Results The vast majority of TBCS measures were significantly associated with the MoCA and A-IADL-Q-30 scores, supporting convergent and ecological validity, respectively; TBCS measures also diverged from the NPI. TBCS measures of global cognition and executive-attentive measures discriminated PD individuals from HCs with acceptable accuracy (AUC = 0.71–0.75), showing, by contrast, a better performance in differentiating PD-MCI from PD-CN groups (AUC = 0.74–0.89). Conclusion TBCS tests are clinimetrically sound tools for identifying cognitive deficits in PD.
Perilead Edema in Deep Brain Stimulation: Long-Term Outcomes and Etiologic Correlates
Luigi G. Remore, Giorgio Fiore, Elena Pirola, Linda Borellini, Francesca Mameli, et al.
Neuromodulation, 2026
Triple perspective: assessing deep brain stimulation outcomes in Parkinson's disease
Denise Mellace, Francesca Mameli, Fabiana Ruggiero, Filippo Cogiamanian, Linda Borellini, et al.
BMC Neurology, 2025
Long-Term Motor and Cognitive Outcome of Deep Brain Stimulation in Patients With Parkinson Disease With a GBA1 Pathogenic Variant
Micol Avenali, Carlo Alberto Artusi, Roberto Cilia, Giulia Giannini, Giada Cuconato, et al.
Neurology, 2025
The Emotional Landscape of Multiple System Atrophy: A Preliminary Personality-Based Perspective
Eleonora Zirone, Giulia Franco, Federica Arienti, Roberta Ferrucci, Alessandro Di Maio, et al.
Journal of Clinical Medicine, 2025
Background: Multiple System Atrophy (MSA) is a rapidly progressing neurodegenerative movement disorder characterized by autonomic failure, parkinsonism, and cerebellar ataxia. While its non-motor symptoms are well-documented, personality features in MSA remain underexplored. This study characterizes the personality traits of non-demented patients with MSA and explores their association with clinical variables. Methods: Twenty-six patients with MSA were assessed using the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF). Dementia was excluded by Montreal Cognitive Assessment. Descriptive statistics and non-parametric analyses were conducted to examine clinical, demographic, and MMPI-2-RF variables. Results: Patients commonly showed elevated scores in somatic domains: Somatic Complaints (39%), Malaise (58%), and Neurological Complaints (85%), as well as in internalizing emotional traits: Low Positive Emotions (39%), Introversion (46%), Suicidal Ideation (46%), and Hopelessness (54%). Externalizing behavioral traits were absent, with only 4–8% of patients showing elevations in aggression or behavioral dysfunction. Strong correlations were found between somatic and emotional traits (r = 0.656, p < 0.001), and between Neurological Complaints and disease duration (r = 0.662, p < 0.001). Conclusions: This exploratory study reveals a distinct personality pattern in MSA, characterized by marked suicidal ideation, emotional vulnerability with internalizing coping, and absence of externalizing behaviors. These features highlight the need for suicide risk screening, interventions to alleviate psychological suffering, and tailored multidisciplinary care. Larger, longitudinal studies are warranted to confirm these preliminary results and clarify whether these traits reflect premorbid personality, early disease manifestations, or secondary responses, as well as their prognostic and clinical relevance.
Letter to the Editors: Comments on “Clinical and Imaging Correlates of Medication Reduction in Globus Pallidus Stimulation for Parkinson's Disease”
Luigi G. Remore, Filippo Cogiamanian, Ioannis U. Isaias, Marco Locatelli
Movement Disorders Clinical Practice, 2025
Exploring the relationship between dystonia and STN-DBS in Parkinson’s disease: insights from a single-centre cohort
Luigi G. Remore, Delia Gagliardi, Linda Borellini, Alfonso Fasano, Valeria Lo Faso, et al.
Neurological Sciences, 2025
Introduction Motor side effects may emerge after deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson’s disease (PD) patients. Out of 60 PD patients, we observed 16 patients displaying de novo dystonic symptoms after the implantation and 11 dystonic PD patients without benefit from the stimulation. We hypothesized that a common neural pathway may cause dystonia in both conditions. Our study aims to investigate the clinical and connectivity substrates of dystonia after STN-DBS. Methods We divided our cohort into four groups: 16 patients displaying dystonia after STN-DBS, 11 patients with previously known dystonia not improving after surgery, 14 patients with dystonic symptoms relieved by the stimulation and 19 controls who never experienced dystonia. MANOVA was used to compare clinical data and the distance of the active contact center from the STN border among the four groups. Finally, we reconstructed the “sour” spots for dystonic symptoms and the associated structural and functional connectivity using a Parkinsonian normative connectome. Results De novo dystonic and not-improved dystonic patients had a statistically significant longer PD duration before surgery (p = 0.001) and a greater active contact-STN distance (p < 0.001). Moreover, the “sour” spots were similar in both groups and structural and functional connectivity profiles were associated with brain areas correlated with dystonia pathophysiology (cerebellum, midbrain, parietal and temporal cortices). Conclusions We formulated a two-hit model for dystonia after STN-DBS: a clinical feature of Parkinsonian patients causes predisposing altered plasticity contributing to dystonic symptoms development when coupled with the stimulation of dystonia-related subcortical and cortical structures.
Regression-based thresholds to detect clinical changes in verbal fluency after STN-DBS in Parkinson's disease
Francesca Mameli, Edoardo Nicolò Aiello, Fabiana Ruggiero, Eleonora Zirone, Linda Borellini, et al.
Parkinsonism and Related Disorders, 2025
Deep Brain Stimulation in Parkinson Disease: A Switch for On/Off Dystonia
Valeria Lo Faso, Luigi Schisano, Luigi Gianmaria Remore, Leonardo Tariciotti, Giorgio Fiore, et al.
World Neurosurgery, 2025
Co-Design of a Mixed Reality Application to Support Freezing of Gait Rehabilitation
Eleonora Chitti, D. Andrea Montereale, Angelica De Sandi, Enrico Mailland, Linda Borrellini, et al.
Segah 2025 2025 IEEE 13th Conference on Serious Games and Applications for Health, 2025
Can total electrical energy (TEED) after subthalamic DBS alter verbal fluency in Parkinson's disease patients? A preliminary evidence
Fabiana Ruggiero, Francesca Mameli, Edoardo Nicolò Aiello, Eleonora Zirone, Filippo Cogiamanian, et al.
CNS Spectrums, 2024
RAB32 mutation in Parkinson's disease [2]
Edoardo Monfrini, Raffaella Minardi, Franco Valzania, Giovanna Calandra-Buonaura, Paola Mandich, et al.
Lancet Neurology, 2024
The Protective Role of Cognitive Reserve: A Preliminary Study on Parkinsonian Patients Undergoing Deep Brain Stimulation
Eleonora Zirone, Fabiana Ruggiero, Maria Takeko Molisso, Roberta Ferrucci, Angelica De Sandi, et al.
Journal of Clinical Medicine, 2024
The role of SWI sequence during the preoperative targeting of the subthalamic nucleus for deep brain stimulation in Parkinson's disease: A retrospective cohort study
Luigi Gianmaria Remore, Leonardo Tariciotti, Giorgio Fiore, Elena Pirola, Linda Borellini, et al.
World Neurosurgery X, 2024
The Clinical Spectrum of ANO3—Report of a New Family and Literature Review
Marco Percetti, Michela Zini, Paola Soliveri, Filippo Cogiamanian, Mariarosa Ferrara, et al.
Movement Disorders Clinical Practice, 2024
Are patients with GBA-Parkinson disease good candidates for deep brain stimulation? A longitudinal multicentric study on a large Italian cohort
Micol Avenali, Roberta Zangaglia, Giada Cuconato, Ilaria Palmieri, Alberto Albanese, et al.
Journal of Neurology Neurosurgery and Psychiatry, 2023
Energy Delivered by Subthalamic Deep Brain Stimulation for Parkinson Disease Correlates With Depressive Personality Trait Shift
Francesca Mameli, Fabiana Ruggiero, Michelangelo Dini, Sara Marceglia, Marco Prenassi, et al.
Neuromodulation, 2023
Case report: Clinical and molecular characterization of two siblings affected by Brody myopathy
Daniele Velardo, Sara Antognozzi, Martina Rimoldi, Serena Pagliarani, Filippo Cogiamanian, et al.
Frontiers in Neurology, 2023
Author Correction: Eight-hours conventional versus adaptive deep brain stimulation of the subthalamic nucleus in Parkinson’s disease (npj Parkinson's Disease, (2021), 7, 1, (88), 10.1038/s41531-021-00229-z)
Tommaso Bocci, Marco Prenassi, Mattia Arlotti, Filippo Maria Cogiamanian, Linda Borellini, et al.
Npj Parkinson S Disease, 2022
Indication and eligibility of glioma patients for awake surgery: A scoping review by a multidisciplinary perspective
Giorgio Fiore, Giorgia Abete-Fornara, Arianna Forgione, Leonardo Tariciotti, Mauro Pluderi, et al.
Frontiers in Oncology, 2022
Peri-lead edema and local field potential correlation in post-surgery subthalamic nucleus deep brain stimulation patients
Marco Prenassi, Linda Borellini, Tommaso Bocci, Elisa Scola, Sergio Barbieri, et al.
Frontiers in Human Neuroscience, 2022
Eight-hours conventional versus adaptive deep brain stimulation of the subthalamic nucleus in Parkinson’s disease
Tommaso Bocci, Marco Prenassi, Mattia Arlotti, Filippo Maria Cogiamanian, Linda Borrellini, et al.
Npj Parkinson S Disease, 2021
Subclinical myopathic changes in COVID-19
Davide Villa, Gianluca Ardolino, Linda Borellini, Filippo Cogiamanian, Maurizio Vergari, et al.
Neurological Sciences, 2021
The Relationship Between Electrical Energy Delivered by Deep Brain Stimulation and Levodopa-Induced Dyskinesias in Parkinson's Disease: A Retrospective Preliminary Analysis
Marco Prenassi, Mattia Arlotti, Linda Borellini, Tommaso Bocci, Filippo Cogiamanian, et al.
Frontiers in Neurology, 2021
Effective Connectivity During Rest and Music Listening: An EEG Study on Parkinson’s Disease
Eleonora Maggioni, Federica Arienti, Stella Minella, Francesca Mameli, Linda Borellini, et al.
Frontiers in Aging Neuroscience, 2021

Filippo Maria Cogiamanian

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Scopus Publications