- In silico clinical trials: concepts and early adoptions
F Pappalardo, G Russo, FM Tshinanu, M Viceconti
Briefings in bioinformatics 20 (5), 1699-1708 2019
Citations: 256
- First evaluation of QuantiFERON-TB Gold Plus performance in contact screening
L Barcellini, E Borroni, J Brown, E Brunetti, D Campisi, PF Castellotti, ...
European respiratory journal 48 (5), 1411-1419 2016
Citations: 182
- Mutations in disordered regions can cause disease by creating dileucine motifs
K Meyer, M Kirchner, B Uyar, JY Cheng, G Russo, ...
Cell 175 (1), 239-253. e17 2018
Citations: 142
- Agent‐based modeling of the immune system: NetLogo, a promising framework
F Chiacchio, M Pennisi, G Russo, S Motta, F Pappalardo
BioMed research international 2014 (1), 907171 2014
Citations: 140
- Scientific and regulatory evaluation of mechanistic in silico drug and disease models in drug development: Building model credibility
FT Musuamba, I Skottheim Rusten, R Lesage, G Russo, R Bursi, L Emili, ...
CPT: Pharmacometrics & Systems Pharmacology 10 (8), 804-825 2021
Citations: 102
- Modeling biology spanning different scales: an open challenge
F Castiglione, F Pappalardo, C Bianca, G Russo, S Motta
BioMed research international 2014 (1), 902545 2014
Citations: 81
- Computational modeling of PI3K/AKT and MAPK signaling pathways in melanoma cancer
F Pappalardo, G Russo, S Candido, M Pennisi, S Cavalieri, S Motta, ...
PLoS One 11 (3), e0152104 2016
Citations: 74
- Immune-checkpoint inhibitors from cancer to COVID-19: A promising avenue for the treatment of patients with COVID-19
S Vivarelli, L Falzone, F Torino, G Scandurra, G Russo, R Bordonaro, ...
International journal of oncology 58 (2), 145-157 2020
Citations: 71
- The combination of artificial intelligence and systems biology for intelligent vaccine design
G Russo, P Reche, M Pennisi, F Pappalardo
Expert Opinion on Drug Discovery 15 (11), 1267-1281 2020
Citations: 69
- Credibility of In Silico Trial Technologies—A Theoretical Framing
M Viceconti, MA Jurez, C Curreli, M Pennisi, G Russo, F Pappalardo
IEEE journal of biomedical and health informatics 24 (1), 4-13 2019
Citations: 62
- Wild boars’ social structure in the Mediterranean habitat
V Maselli, D Rippa, G Russo, R Ligrone, O Soppelsa, B D’Aniello, P Raia, ...
Italian Journal of Zoology 81 (4), 610-617 2014
Citations: 60
- In silico trial to test COVID-19 candidate vaccines: a case study with UISS platform
G Russo, M Pennisi, E Fichera, S Motta, G Raciti, M Viceconti, ...
BMC bioinformatics 21, 1-16 2020
Citations: 52
- In silico design of recombinant multi-epitope vaccine against influenza A virus
A Maleki, G Russo, GA Parasiliti Palumbo, F Pappalardo
BMC bioinformatics 22 (Suppl 14), 617 2021
Citations: 48
- A computational model to predict the immune system activation by citrus-derived vaccine adjuvants
F Pappalardo, E Fichera, N Paparone, A Lombardo, M Pennisi, G Russo, ...
Bioinformatics 32 (17), 2672-2680 2016
Citations: 47
- Computational modelling approaches to vaccinology
F Pappalardo, D Flower, G Russo, M Pennisi, S Motta
Pharmacological research 92, 40-45 2015
Citations: 47
- Possible Contexts of Use for In Silico Trials Methodologies: A Consensus-Based Review
M Viceconti, L Emili, P Afshari, E Courcelles, C Curreli, N Famaey, L Geris, ...
IEEE Journal of Biomedical and Health Informatics 25 (10), 3977-3982 2021
Citations: 42
- The potential of computational modeling to predict disease course and treatment response in patients with relapsing multiple sclerosis
F Pappalardo, G Russo, M Pennisi, GA Parasiliti Palumbo, G Sgroi, ...
Cells 9 (3), 586 2020
Citations: 42
- Examining the pre-war health burden of Ukraine for prioritisation by European countries receiving Ukrainian refugees
V Marchese, B Formenti, N Cocco, G Russo, J Testa, F Castelli, ...
The Lancet Regional Health–Europe 15 2022
Citations: 38
- Computational modeling of the expansion of human cord blood CD133+ hematopoietic stem/progenitor cells with different cytokine combinations
F Gullo, M Van Der Garde, G Russo, M Pennisi, S Motta, F Pappalardo, ...
Bioinformatics 31 (15), 2514-2522 2015
Citations: 38
- Septins as modulators of endo-lysosomal membrane traffic
K Song, G Russo, M Krauss
Frontiers in cell and developmental biology 4, 124 2016
Citations: 37