Dr. Hasan Abd Ali Khudhair is a Lecturer at Southern Technical University, Al-Nasiriyah Technical Institute, Iraq. He is with strong interest in Molecular Clinical Immunology and specialty in this field. His Ph. D. thesis was focused on immunology of pancreatic beta cells stress and/or death in type 1 diabetes mellitus patients. He was published numerous scientific researches and currently working as a reviewer in several scientific journals. His reviewing interests: Clinical Immunology, Clinical Immunobacteriology, Molecular Clinical Immunology, Endocrinology and Immunopathology.
EDUCATION
Ph. D. Degree in Medical Laboratory Technology (2020)
M. Sc. Degree in Medical Laboratory Technology (2014)
B. Sc. Degree in Laboratory Investigations Science (2011)
Correlation between adiponectin levels, insulin resistance, and oxidative stress in polycystic ovary syndrome patients: implications for novel therapeutic approaches Zainab Mohammed Talib, Khwam R. Hussein, Hasan Abd Ali Khudhair Anaesthesia Pain and Intensive Care, 2025 Background & objective: Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder characterized by metabolic dysfunction, including insulin resistance and oxidative stress. Adiponectin, an adipokine that has anti-inflammatory and insulin-sensitizing properties, may be essential to the pathogenesis of PCOS.Methodology: To assess the relationship between serum adiponectin levels, IR indices (insulin, fasting blood glucose, HOMA-IR), oxidative stress (as determined by the total antioxidant capacity), and lipid profile parameters in PCOS women in comparison to healthy controls. A case-control study was conducted involving 45 PCOS patients and 45 age-matched HCs. Biochemical markers, including insulin, FBG, lipid profile, adiponectin, and TAC were analyzed. Statistical tests such as t-test, Chi-square, Spearman's correlation, and Mann-Whitney U test were applied.Results: PCOS patients exhibited significantly elevated levels of total cholesterol, LDL-C and reduced adiponectin in comparison to healthy controls (HCs). Although levels of HOMA-IR and insulin were unexpectedly lower in PCOS patients, FBG was higher. HOMA-IR and adiponectin were discovered to have a paradoxical positive relationship. TAC showed a non-significant inverse relationship with HOMA-IR in PCOS patients but a significant one in healthy controls. Higher TAC levels were associated with elevated TG and VLDL, and reduced HDL levels.Conclusions: The findings of the study indicate a complex interaction among adiponectin, oxidative stress, and insulin resistance in PCOS, with potential dysregulation in adiponectin signaling. Elevated TAC levels may reflect compensatory mechanisms rather than protection, emphasizing the need for targeted therapeutic strategies.Keywords: PCOS; Adiponectin; HOMA-IR; Oxidative Stress; DyslipidemiaAbbreviations: ADP: adiponectin, BMI: body mass index, ELISA: enzyme-linked immunosorbent assay, FBG: fasting blood glucose, HDL-C: high-density lipoprotein-cholesterol, HCs: healthy controls, HOMA-IR: homeostatic model assessment of IR, IR: insulin resistance, LDL: low-density lipoprotein, OS: oxidative stress, PCOS: Polycystic ovary syndrome, ROS: reactive oxygen species, SD: standard deviations, T2D: type 2 diabetes, TAC: total antioxidant capacity, TC: total cholesterol, TG: triglyceride, VLDL: very low-density lipoprotein.Citation: Talib ZM, Hussein KR, Khudhair HAA. Correlation between adiponectin levels, insulin resistance, and oxidative stress in polycystic ovary syndrome patients: Implications for novel therapeutic approaches. Anaesth. pain intensive care 2025;29(8):919-931. DOI: 10.35975/apic.v29i8.3019.Received: June 17, 2025; Revised: August 21, 2025; Accepted: August 21, 2025
Impact of Mineral Metabolism and Hormonal Dysregulation on Bone Health in β-Thalassemia Major: A Case–control Biochemical Study Murtadha Ali Nazzal, Abdulkareem M. Jewad, Hasan Abd Ali Khudhair Journal of Applied Hematology, 2025 BACKGROUND: β-thalassemia major (β-TM) is a genetic disorder characterized by excessive iron accumulation caused by continued blood transfusion, together with the development of chronic anaemia, which may also cause complications related to weakened bones. OBJECTIVES: The purpose of this research was to investigate and compare the concentration levels of different biochemical markers related to mineral metabolism; phosphate (PO4), calcium (Ca +2 ), vitamin D3 (VD3), and the hormonal markers related to bone metabolism; parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF-23) against those of healthy controls (HCs), as well as the levels of the biomarker used to evaluate the potential for iron overload; ferritin (FER) and the concentration of hemoglobin (Hb). MATERIALS AND METHODS: Between September 2024 and January 2025, at the Thi-Qar Centre for Genetic Disorders in Thi-Qar, Iraq, an investigation was carried out with a biochemical design as a case-control trial. The sample consisted of 50 β-TM patients matched on sex between the ages of 18-45 years, who were compared to 49 HCs (24 male, 25 female), and were between the ages of 18-49 years. The serum concentrations of the study biomarkers were assessed using either spectrophotometric or standardised immunoassays and analysed using either the Mann-Whitney U Test, Chi-Square, t -test or Spearman's correlation coefficient. RESULTS: There was a statistically significant ( P < 0.001) increase in FGF-23, PO4 and FER levels in patients compared to the healthy group with significantly decreased levels of VD3, Ca +2 , PTH and Hb. There was a very strong negative correlation between PTH and PO4 ( r = -0.93; P < 0.001) and a strong positive correlation between PTH and Ca 2+ ( r = 0.57; P < 0.001). FGF-23 levels were also elevated, yet there were no statistically significant correlations between FGF-23 and any of the other parameters included in this analysis. Therefore, it appears that FGF-23 is regulated in a different manner than the other biomarkers assessed in this study. CONCLUSIONS: Dysregulated levels of mineral and/or hormonal suggest decreased bone turnover in patients with β-TM.
Association of Hemoglobin and Iron Overload with Bone Turnover Markers in β-Thalassemia Major Patients: A Novel Biomarker Approach Murtadha Ali Nazzal, Abdulkareem M. Jewad, Hasan Abd Ali Khudhair Journal of Applied Hematology, 2025 BACKGROUND: β-thalassemia major is a severe genetic disorder characterized by chronic anemia and iron overload due to frequent transfusions. These pathological changes can significantly disrupt bone metabolism, increasing the risk of osteoporosis and fractures. OBJECTIVES: The objective is to investigate the association between hemoglobin (Hb) levels, iron overload (serum ferritin), bone turnover markers, osteoprotegerin (OPG), receptor activator of nuclear factor-kappa β ligand (RANKL), bone-specific alkaline phosphatase (BAP), and C-terminal telopeptides of type I collagen (CTX), in patients with β-thalassemia major. MATERIALS AND METHODS: In Thi-Qar Province, a case–control research was carried out at the Genetic and Hematology Center. Fifty β-thalassemia major patients (25 males, 25 females; 18–45 years) receiving regular blood transfusions were compared to 49 healthy controls (24 males, 25 females; 18–49 years). Serum ferritin, Hb, OPG, RANKL, BAP, and CTX levels were measured using automated analyzers and enzyme-linked immunosorbent assay kits. Statistical analyses included t-tests, correlation coefficients, and frequency distributions. RESULTS: Compared to controls, β-thalassemia major patients had significantly lower Hb levels (mean 7.45 ± 1.22 g/dL, P < 0.001) and markedly elevated ferritin (mean 1434 ± 1079 ng/mL, P < 0.001). OPG, RANKL, BAP, and CTX levels were all elevated in the patient group (P < 0.05 for all), indicating a significant change in bone turnover markers. Thus, RANKL and CTX (r = 0.91), CTX and BAP (r = 0.94), and RANKL and OPG (r = 0.90) all showed strong positive correlations, suggesting coordinated dysregulation of bone metabolism. CONCLUSIONS: Iron overload and chronic anemia are the primary drivers of the severe disruptions in bone turnover linked to β-thalassemia major. A high bone turnover state is suggested by elevated bone resorption and formation biomarkers, which could be a factor in skeletal consequences. The possible use of these indicators to manage bone disease and diagnose β-thalassemia major early is supported by these results.
Vitamin D in regulating immune response in patients with recurrent pregnancy loss: a case-control study Hasan Abd Ali Khudhair Medical Journal of Indonesia, 2025 BACKGROUND Recurrent pregnancy loss (RPL) is linked to lower vitamin D levels and altered immune responses, though unclear mechanisms. This study aimed to identify the effect of vitamin D on the balance between interleukin (IL)-10/IL-17A in women with RPL. METHODS This case-control study was conducted at the Bint Al-Huda Teaching Hospital, Thi-Qar Governorate, Iraq, from August 2022 to March 2023. Three study groups were included: RPL (47 women), non-aborted pregnant (40 women), and control (38 women). The sera concentrations of IL-17A, vitamin D, and IL-10 had been quantitatively detected using ELISA. SPSS was used for statistical analysis. RESULTS Women with RPL had significantly lower vitamin D levels (19.6 ng/ml) and higher IL-17A levels (35.66 ng/l) than the non-aborted pregnant (23.46 ng/ml, 24.04 ng/l) and control groups (25.69 ng/ml, 19.87 ng/l). IL-10 levels were substantially depleted in the RPL group (3.96 pg/ml), leading to a statistically lower IL-10/IL-17A ratio (0.19) than in the non-aborted pregnant (0.58) and control (1.60) groups. Regression analysis revealed a valuable positive association between vitamin D and IL-17A in all groups and between vitamin D and IL-10/IL-17A ratio in RPL and control groups. Vitamin D was also significantly associated with IL-10 in the non-aborted pregnant group. However, no statistical relationship was reported between vitamin D and IL-10 levels in the RPL and control groups. CONCLUSIONS Increased IL-17A and decreased IL-10 contributed to unexplained RPL. The IL-10/IL-17A ratio predicted endometrial function, and vitamin D affects these cytokines, potentially reducing inflammation.
Exploring the diagnostic potential of micro-RNA-320 and anti-Müllerian hormone in women with polycystic ovary syndrome – a case-control study Zainab Mohammed Talib, Khwam R. Hussein, Hasan Abd Ali Khudhair European Journal of Clinical and Experimental Medicine, 2025 Introduction and aim. Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder characterized by hormonal imbalance, insulin resistance, and reproductive dysfunction. Due to its heterogeneous clinical presentation, diagnosis remains challenging. MicroRNA-320a-3p and anti-Müllerian hormone (AMH) have recently emerged as promising biomarkers. This study aimed to assess their diagnostic potential in women with PCOS.Material and methods. A case-control study was performed in 90 women aged 18–40 years, including 45 patients with polycystic ovary syndrome and 45 age- and body mass index-matched healthy controls. Hormonal and metabolic markers were measured using standard immunoassays, and the expression of microRNA-320a-3p was quantified using real-time polymerase chain reaction. Results. Patients with polycystic ovary syndrome demonstrated significantly higher levels of luteinizing hormone (9.45±6.0 vs 5.09±2.2 mIU/mL), increased luteinizing hormone to follicle-stimulating hormone ratio (1.64±0.87 vs 0.76±0.3), and elevated fasting blood glucose (105.5±14.7 vs 94.3±13.5 mg/dL), all with p<0.001. Contrary to expectations, insulin and homeostatic model assessment for insulin resistance values were lower in the polycystic ovary syndrome group, possibly reflecting a predominance of non-obese phenotypes. AMH levels were also reduced (2.27±1.0 vs 3.34±1.1 ng/mL, p<0.001). Expression of microRNA-320a-3p was significantly downregulated (0.61±1.27 vs 2.81±5.03-fold, p=0.0009). MicroRNA-320a-3p expression correlated positively with luteinizing hormone levels and the luteinizing hormone to follicle-stimulating hormone ratio, while AMH was associated with insulin resistance. The combined use of both markers improved diagnostic differentiation between groups. Conclusion. MicroRNA-320a-3p and AMH show promise as diagnostic biomarkers in polycystic ovary syndrome. Their integration with traditional clinical markers may enhance diagnostic accuracy and provide deeper insight into the pathophysiological complexity of the disorder.
Serum ceramide and meteorin-like protein as potential biomarkers of type 2 diabetes mellitus Hussein Saeed Sfayyih International Journal of Medical Biochemistry, 2025 . Objectives: The recent research aims to detect ceramide and meteorin-like proteins as potential markers for identifying type 2 diabetes and monitoring its progression. Methods: A cross-sectional study included three groups: type 2 diabetes without hypertension, type 2 diabetes with hypertension, and healthy control groups. Serum ceramide, meteorin-like protein, insulin, fasting blood glucose, lipid profile, and hemoglobin A1c levels were measured. Results: Higher concentrations of ceramide, fasting blood glucose, hemoglobin A1c, and the homeostatic model assessment of insulin resistance were observed in both type 2 diabetes groups compared to the healthy control group. In the type 2 diabetes group with hypertension, total cholesterol was elevated compared to the other study groups; however, the concentration of low/very-low-density lipoprotein was statistically higher than in the healthy control group. Serum meteorin-like protein was statistically lower in the type 2 diabetes group with hypertension than in the other study groups and positively correlated with fasting blood glucose in type 2 diabetes with hypertension. The ceramide level showed a significant positive correlation with meteorin-like protein across all study groups and with systolic blood pressure in the type 2 diabetes group with hypertension. In type 2 diabetes without hypertension, ceramide negatively correlated with the homeostatic model assessment of insulin resistance and fasting blood glucose. Conclusion: Elevated ceramide levels could accelerate type 2 diabetes progression. Meteorin-like protein levels were lower in type 2 diabetes with hypertension and higher in type 2 diabetes without hypertension. It positively correlated with fasting blood glucose in type 2 diabetes with hypertension, suggesting that meteorin-like protein may play a potential role in glycemic and blood pressure control.
Clinical significances of circulating serum fetuin-A, netrin-1, and a-hydroxybutyrate levels in type 2 diabetes mellitus patients with and without hypertension Hasan Abd Ali Khudhair, Abdulkareem M. Jewad, Hasan Abd Ali Khudhair Anaesthesia Pain and Intensive Care, 2024 Background & Objective: Type 2 diabetes (T2D) is a rising global health issue, with biomarkers such as fetuin-A (Fet-A), netrin-1 (NTN-1), and alpha-hydroxybutyrate (α-HB) showing potential for early diagnosis and management. These biomarkers can help predict T2D risk and understand insulin resistance (IR), emphasizing the need for further research. The current investigation evaluated the effectiveness of Fet-A, NTN-1, and, α-HB as novel biomarkers to diagnose T2D with hypertension.Methodology: A cross-sectional study was conducted from August to December 2023, involved 60 diabetic participants, which were divided into two groups: T2D without hypertension and T2D with hypertension. A third group consisted of 30 healthy controls (HC) for comparison. Serum samples were analyzed for fasting blood glucose (FBG) using the Roche/Cobas c111 system, as well as insulin, Fet-A, NTN-1, and α-HB levels using kits for the enzyme-linked immune-sorbent assay (ELISA). Descriptive statistics were used in the statistical package for social sciences (SPSS) for data analysis.Results: The study found significantly elevated Fet-A, NTN-1, and α-HB levels in T2D patients compared to HC, with no significant differences between T2D subgroups. Fetuin-A and α-HB showed non-significant correlations with FBG and homeostatic model assessment of IR (HOMA-IR) across all groups. NTN-1 positively correlated with FBG and HOMA-IR in T2D patients with hypertension.Conclusions: Elevated levels of fetuin-A and netrin-1, regardless of the presence of hypertension, are suggested by the study as possible biomarkers for the diagnosis of T2D. Netrin-1's significant correlation with HOMA-IR in hypertensive T2D patients underscores its utility in assessing insulin resistance severity. Although alpha-hydroxybutyrate levels were higher in T2D patients, their non-significant correlation with FBG and HOMA-IR requires further research. These biomarkers could aid in early diagnosis and disease monitoring for T2D management.Abbreviations: α-KB - α-ketobutyrate; ELISA - enzyme linked immune-sorbent assay; FA - fatty acids; FBG - fasting blood glucose; Fet-A - fetuin-A; HOMA-IR - homeostatic model assessment of IR; IR - insulin resistance; NAD - nicotinamide adenine dinucleotide; NADH - nicotinamide adenine dinucleotide hydrogen; ng - nanograms; NTN-1 - netrin-1; PB - peripheral blood; pg - picogram; SPSS - Statistical Package for Social Sciences; T2D - Type-2 diabetes mellitus; α-HB - alpha-hydroxybutyrateKeywords: Diabetes, Fetuin-A, Netrin-1, α-HB, HOMA-IR.Citation: Sfayyih HS, Jewad AM, Khudhair HAA. Clinical significance of circulating serum fetuin-A, netrin-1, and ɑ-hydroxybutyrate levels in type-2 diabetes mellitus patients with and without hypertension. Anaesth. pain intensive care 2024;28(5):883−893; DOI: 10.35975/apic.v28i5.2569Received: Jul 22, 2024; Reviewed: August 10, 2024; Accepted: August 15, 2024
Evaluation of the Possible Pathophysiological Role of Redox Status in Patients with Sickle Cell Anemia Wiqar Fadheel Shanan, Mahdi Murshd Thuwaini, Hasan Abd Ali Khudhair Journal of Applied Hematology, 2024 BACKGROUND: The disease of sickle cell anemia (SCA) is an inherited blood disease that causes several complications, and oxidative stress (OS) may play a very important role in its complications and pathophysiology. OBJECTIVE: The aims of the study is to evaluate the possible pathophysiological role of some antioxidant and oxidant biomarkers within SCA patients and to evaluate the correlation of OS and atherogenic index of plasma (AIP) to predict the cardiovascular risk in SCA subjects. MATERIALS AND METHODS: A case–control research includes three study groups: SCA patients, sickle cell trait (SCT) subjects, and healthy controls (HCs). All study groups were evaluated for their serum catalase (CAT), serum superoxide dismutase (SOD), glutathione peroxidase (GPx), and malondialdehyde (MDA) as well as plasma triglycerides and high-density lipoprotein cholesterol. Data were collected, tabulated, and statistically analyzed using (SPSS) version 31 program. The frequencies, relative frequencies, and means were obtained as descriptive methods. The associations among parameters were obtained using the Chi-square statistical method. RESULTS: The results revealed significantly lower levels of serum SOD and GPx among sickle cell disease (SCD) and SCT subjects than the HCs, whereas the inverse findings were reported for CAT and AIP. However, the MDA results revealed a significantly higher level in SCD patients compared to SCT and HC. Furthermore, the levels of SOD and MDA were positively associated in all study groups, and the levels of GPx and MDA were negatively correlated in SCD and SCT groups. The AIP was positively correlated with MDA in the SCT group and negatively correlated with CAT in the SCD group. CONCLUSIONS: The conclusion of the study indicated the presence of an OS and antioxidant compensatory status in patients with SCD and the SCT subjects. The altered biomarkers in SCA patients made it clear that the impairment and generation of OS in this disease, as well as antioxidant biomarkers, are contributory factors toward cellular redox homeostasis. This addressed the aim of the study.
Detecting the Prevalence of Hepatitis C Virus among Iraqi People Hasan Abd Ali Khudhair, Ali A H Albakaa, Khwam R Hussein International Journal of Biomedicine, 2023 Background: Infection with the hepatitis C virus (HCV) is a major public health issue worldwide and remains a vital etiology of long-term hepatitis. This study aimed to detect the prevalence of HCV infection among Iraqi people. This research was proposed to detect the frequency of HCV infection in renal failure patients, thalassemia patients, blood donors, and Iraqi medical staff. Such prevalence potentially could assist in the development of a preventive program for this infection and orient future studies. Methods and Results: Cross-sectional research was conducted in Thi-Qar Province (Iraq). The enrolled 1650 individuals (1180 males and 470 females, age range of 1-85 years) were classified into four study groups. Group 1 included 120 patients with renal failure, Group 2 included 220 patients suffering from thalassemia, Group 3 included 1259 blood donor subjects, and Group 4 included 51 subjects from the medical staff. Serum anti-HCV-IgG-Abs were detected qualitatively by a human HCV-IgG-ELISA Kit (MyBioSource, USA). The findings revealed that out of 1650 subjects, only 53(3.2%) were infected with HCV. The highest prevalence was reported among thalassemia patients 34/220(15.45%), followed by renal failure patients 8/120(6.66%) and then the medical staff group 3/51(5.88%), whereas the lowest prevalence was reported among the blood donor group 8/1259(0.64%). The total infection rate of HCV was higher among males [33/53(62.3%)] than females [20/53(37.7%)], with significant differences (P<0.05). We found a significant difference in HCV infection rate according to the age range of the study subjects (P<0.05). The higher infection percentages of 29/53(54.7%) and 15/53(28.3%) were found in age groups of 1-20 years and 21-40 years, respectively, followed by the age group of 41-60 years, which had infection percentages of 7/53(13.2%), while the lowest infection rate was reported in the age group of more than 60 years, which was 2/53(3.8%). Conclusion: The frequency rate of HCV infection among Iraqi people is similar to those in most Asian and non-Asian studied populations, and the infection rate was higher in males and inversely correlated with the age of the subjects. The main routes of HCV infection were blood transfusions, renal dialysis, and HCWs. Thalassemic and hemodialysis patients were potentially vulnerable to HCV infection. Effective screening methods and blood donor screening protocols are likely required to prevent the spread of HCV infection.
Evaluating the roles of interleukin-17, C3, C4, antinuclear antibody, and antiphospholipid antibody in the pathophysiology of systemic lupus erythematosus HAA Khudhair, SF Lafta European Journal of Clinical and Experimental Medicine , 2026 2026
Exploring the diagnostic potential of micro-RNA-320 and anti-Müllerian hormone in women with polycystic ovary syndrome‒a case-control study ZM Talib, KR Hussein, HAA Khudhair European Journal of Clinical and Experimental Medicine 23 (4), 1000–1010 … , 2025 2025
Correlation between adiponectin levels, insulin resistance, and oxidative stress in polycystic ovary syndrome patients: implications for novel therapeutic approaches ZM Talib, KR Hussein, HAA Khudhair Anaesthesia, Pain & Intensive Care 29 (8), 919-931 , 2025 2025
Impact of Mineral Metabolism and Hormonal Dysregulation on Bone Health in β-Thalassemia Major: A Case–control Biochemical Study MA Nazzal, AM Jewad, HAA Khudhair Journal of Applied Hematology 16 (4), 334-341 , 2025 2025
Association of Hemoglobin and Iron Overload with Bone Turnover Markers in β-Thalassemia Major Patients: A Novel Biomarker Approach MA Nazzal, AM Jewad, HAA Khudhair Journal of Applied Hematology 16 (3), 275-280 , 2025 2025
Vitamin D in regulating immune response in patients with recurrent pregnancy loss: a case-control study HAA Khudhair Medical Journal of Indonesia 34 (1), 37-43 , 2025 2025
Vitamin D in regulating immune response in patients with recurrent pregnancy loss: a case-control study H Abd Ali Khudhair Faculty Of Medicine Universitas Indonesia , 2025 2025
Serum ceramide and meteorin-like protein as potential biomarkers of type 2 diabetes mellitus. HS Sfayyih, AM Jewad, HA Ali Khudhair International Journal of Medical Biochemistry 8 (1) , 2025 2025 Citations: 1
Vitamin E and Selenium Status as Antioxidants Biomarkers in Patients with Sickle Cell Anemia WF Shanan, MM Thuwaini, HAA Khudhair Thi-qar Medical journal 28 (2), 169-187 , 2024 2024
Clinical significances of circulating serum fetuin-A, netrin-1, and ɑ-hydroxybutyrate levels in type 2 diabetes mellitus patients with and without hypertension HS Sfayyih, AM Jewad, HAA Khudhair Anaesthesia, Pain & Intensive Care 28 (5), 883-893 , 2024 2024 Citations: 1
Clinical significances of circulating serum fetuin-A, netrin-1, and ɑ-hydroxybutyrate levels in type 2 diabetes mellitus patients with and without hypertension. Anaesth Pain … HS Sfayyih, AM Jewad, HAA Khudhair Anaesthesia, Pain & Intensive Care 28, 883-893 , 2024 2024
Evaluation of the Possible Pathophysiological Role of Redox Status in Patients with Sickle Cell Anemia WF Shanan, MM Thuwaini, HAA Khudhair Journal of Applied Hematology 15 (3), 219-227 , 2024 2024 Citations: 1
Evaluation the Role of Certain Pancreatic Beta Cells Stress and/or Death Biomarkers in Patients with Diabetes Mellitus Type 1 HC Awad, KR Hussein, HAA Khudhair, MT Altemimi University of Thi-Qar Journal Of Medicine 26 (2), 130-145 , 2023 2023 Citations: 1
MICRORNA-21 AS NOVEL BIOMARKER FOR PANCREATIC BETA CELLS STRESS AND/OR DEATH IN PATIENTS WITH DIABETES MELLITUS TYPE HC Awad, KR Hussein, HAA Khudhair EUROMEDITERRANEAN BIOMEDICAL JOURNAL 18 (23), 108-114 , 2023 2023 Citations: 2
A study of the roles of some immunological biomarkers in the diagnosis of rheumatoid arthritis HAA Khudhair Journal of Medicine and Life 16 (8), 1194 , 2023 2023 Citations: 18
The Role of Helicobacter pylori in Induction of Gastric Autoimmunity SJ Abd-Alsaheb, HAA Khudhair, KM Dakhel University of Thi-Qar Journal of Science 10 (1 (SI)), 210-218 , 2023 2023
Evaluation of Selenium and Vitamin E Levels in Women with Recurrent Miscarriage ZJ AbduLshaheed, AAH Albakaa, HAA Khudhair University of Thi-Qar Journal of Science 10 (1 (SI)), 77-83 , 2023 2023 Citations: 1
Study the role of oxidative stress in helicobacter pylori induced gastro-intestinal diseases SJ Abd-alsaheb, KM Dakhel, HAA Khudhair International Journal of Health Sciences 6 (S7), 4208–4223 , 2022 2022
Study the Effect of Pregnancy on Oxidative Stress Status in Pregnant Women with Gingivitis HAA Khudhair, NA Hamzah, WRN Al Muhsen Journal of Medicinal and Chemical Sciences 5 (7), 1253-1264 , 2022 2022 Citations: 2
Role of Vitamin D, Interleukin-17A and Interleukin-10 Levels in Women with Recurrent Miscarriage ZJ AbduLshaheed, AAH Albakaa, HAA Khudhair International journal of health sciences 6 (S5), 6149-6165 , 2022 2022
MOST CITED SCHOLAR PUBLICATIONS
A study of the roles of some immunological biomarkers in the diagnosis of rheumatoid arthritis HAA Khudhair Journal of Medicine and Life 16 (8), 1194 , 2023 2023 Citations: 18
Detection the Prevalence of Hepatitis C Virus among Iraqi People HAA Khudhair, AAH Albakaa, KR Hussein bioRxiv, 2020.11. 28.401968 , 2020 2020 Citations: 11
Beta-cell Death and/or Stress Biomarkers in Diabetes Mellitus Type 1 MM Sheet, HAA Khudhair Al-Kufa University Journal for Biology 11 (1), 108-119 , 2019 2019 Citations: 7
Changes in Blood Biochemical Parameters in Bodybuilders Using Supplements, Steroids and their Effect on the Kidneys in Iraq WRNAM Ali A. H. Albakaa , Hasan Abd Ali Khudhair Annals of Tropical Medicine and Public Health 23 (13A), 231-334 , 2020 2020 Citations: 4
MICRORNA-21 AS NOVEL BIOMARKER FOR PANCREATIC BETA CELLS STRESS AND/OR DEATH IN PATIENTS WITH DIABETES MELLITUS TYPE HC Awad, KR Hussein, HAA Khudhair EUROMEDITERRANEAN BIOMEDICAL JOURNAL 18 (23), 108-114 , 2023 2023 Citations: 2
Study the Effect of Pregnancy on Oxidative Stress Status in Pregnant Women with Gingivitis HAA Khudhair, NA Hamzah, WRN Al Muhsen Journal of Medicinal and Chemical Sciences 5 (7), 1253-1264 , 2022 2022 Citations: 2
Serum ceramide and meteorin-like protein as potential biomarkers of type 2 diabetes mellitus. HS Sfayyih, AM Jewad, HA Ali Khudhair International Journal of Medical Biochemistry 8 (1) , 2025 2025 Citations: 1
Clinical significances of circulating serum fetuin-A, netrin-1, and ɑ-hydroxybutyrate levels in type 2 diabetes mellitus patients with and without hypertension HS Sfayyih, AM Jewad, HAA Khudhair Anaesthesia, Pain & Intensive Care 28 (5), 883-893 , 2024 2024 Citations: 1
Evaluation of the Possible Pathophysiological Role of Redox Status in Patients with Sickle Cell Anemia WF Shanan, MM Thuwaini, HAA Khudhair Journal of Applied Hematology 15 (3), 219-227 , 2024 2024 Citations: 1
Evaluation the Role of Certain Pancreatic Beta Cells Stress and/or Death Biomarkers in Patients with Diabetes Mellitus Type 1 HC Awad, KR Hussein, HAA Khudhair, MT Altemimi University of Thi-Qar Journal Of Medicine 26 (2), 130-145 , 2023 2023 Citations: 1
Evaluation of Selenium and Vitamin E Levels in Women with Recurrent Miscarriage ZJ AbduLshaheed, AAH Albakaa, HAA Khudhair University of Thi-Qar Journal of Science 10 (1 (SI)), 77-83 , 2023 2023 Citations: 1
Detection of Beta-cell Stress and/or Death Biomarkers in Patients with Diabetes Mellitus Type 1 and their First Degree Relatives HAA Khudhair 2020 Citations: 1
Possible Roles of miRNAs-25 and 375 as Potent Biomarkers for β-cells Stress and/or Death in Diabetes Type 1 Patients and their First Degree Relatives MMSHAA Khudhair International Journal of Pharmaceutical Research 11 (3), 148-155 , 2019 2019 Citations: 1
Study the Relationship between Helicobacter pylori Infection and ABO Blood Groups and Rh Status HAA Khudhair Journal of College of Education for Pure Sciences(JCEPS) 7 (3), 48-56 , 2017 2017 Citations: 1
Evaluating the roles of interleukin-17, C3, C4, antinuclear antibody, and antiphospholipid antibody in the pathophysiology of systemic lupus erythematosus HAA Khudhair, SF Lafta European Journal of Clinical and Experimental Medicine , 2026 2026
Exploring the diagnostic potential of micro-RNA-320 and anti-Müllerian hormone in women with polycystic ovary syndrome‒a case-control study ZM Talib, KR Hussein, HAA Khudhair European Journal of Clinical and Experimental Medicine 23 (4), 1000–1010 … , 2025 2025
Correlation between adiponectin levels, insulin resistance, and oxidative stress in polycystic ovary syndrome patients: implications for novel therapeutic approaches ZM Talib, KR Hussein, HAA Khudhair Anaesthesia, Pain & Intensive Care 29 (8), 919-931 , 2025 2025
Impact of Mineral Metabolism and Hormonal Dysregulation on Bone Health in β-Thalassemia Major: A Case–control Biochemical Study MA Nazzal, AM Jewad, HAA Khudhair Journal of Applied Hematology 16 (4), 334-341 , 2025 2025
Association of Hemoglobin and Iron Overload with Bone Turnover Markers in β-Thalassemia Major Patients: A Novel Biomarker Approach MA Nazzal, AM Jewad, HAA Khudhair Journal of Applied Hematology 16 (3), 275-280 , 2025 2025
Vitamin D in regulating immune response in patients with recurrent pregnancy loss: a case-control study HAA Khudhair Medical Journal of Indonesia 34 (1), 37-43 , 2025 2025
Publications
Changes in Blood Biochemical Parameters in Bodybuilders Using Supplements, Steroids and their Effect on the Kidneys in Iraq (2020)
Possible Roles of miRNAs-25 and 375 as Potent Biomarkers for β-cells Stress and/or Death in Diabetes Type 1 Patients and their First Degree Relatives (2019)
Detection of Potential β-cell Stress and/or Death Biomarkers in Patients with Type 1 Diabetes Mellitus in Thi-Qar Province (Ph. D. Thesis, 2019)
Beta-cell Death and/or Stress Biomarkers in Diabetes Mellitus Type 1 (2019)
Study the Relationship between Helicobacter pylori Infection and ABO Blood Groups and RH Status (2017)
The Role of CagA+ Strains in the Immune Response in Helicobacter pylori Patients (2014)
Humoral and Cell Mediated Immuno-Modulatory Trend in Helicobacter pylori-Induced Gastrointestinal Diseases (M.Sc. Thesis, 2013)
