Luiz Claudio de Almeida Barbosa

LUIZ CLÁUDIO de Almeida Barbosa, natural de Além Paraíba, MG, é graduado em Química e mestre em Agroquímica pela Universidade Federal de Viçosa (UFV) – com aperfeiçoamento em Química de Produtos Naturais pela Universidade Federal de Minas Gerais (UFMG) – e Ph.D. na área de Síntese Orgânica pela Universidade de Reading (Inglaterra). Realizou estágio de pós-doutoramento na Universidade de Oxford (Inglaterra). Foi Professor Titular do Departamento de Química da UFV até 2012, quando se tornou professor da UFMG. Pesquisador do CNPq desde 1992, publicou mais de 270 artigos científicos. É autor do livro-texto INTRODUÇÃO À QUÍMICA pela Pearson Education do Brasil (. Publicou também pela Editora UFV “Os Pesticidas, o Homem e o Meio Ambiente” e “Espectroscopia no Infravermelho na Caracterização de Compostos Orgânicos”; pela Editora Letramento o livro Nitrogênio: o sétimo elemento.

EDUCATION

PhD - University of Reading (1991); Post-doctoral research Fellow, University of Oxford (2009)

RESEARCH INTERESTS

Organic Synthesis; Natural Products; Essential Oils; History of Chemistry.

Scopus Publications

Synthesis and structure-activity relationships of novel biphenyl containing tetronamides with cyanobactericidal activity
Júnio Gonçalves Silva, Amanda Silva de Miranda, Daiane Szczerbowski, André Mauricio de Oliveira, Giuseppe Forlani, and Luiz Claudio Almeida Barbosa
Elsevier BV



Antibiofilm effect of rubrolide analogues and derived lactams on single-species biofilms
Bernardo Born Passoni, Esteban Rodriguez Herrero, Eduarda Blasi Magini, Andrea de Lima Pimenta, Luiz Claudio Almeida Barbosa, Ulisses Alves Pereira, Helena Cristina Oliveira Francisco, Wim Teughels, and Cesar Augusto Magalhães Benfatti
Elsevier BV



Natural Rubrolides and Their Synthetic Congeners as Inhibitors of the Photosynthetic Electron Transport Chain
Milandip Karak, Jaime A. M. Acosta, Héctor F. Cortez-Hernandez, Johnny L. Cardona, Giuseppe Forlani, and Luiz C. A. Barbosa
American Chemical Society (ACS)
Rubrolides are a family of naturally occurring 5-benzylidenebutenolides, which generally contain brominated phenol groups, and nearly half of them also present a chlorine attached to the butenolide core. Seven natural rubrolides were previously synthesized. When these compounds were tested against the model plant Raphanus sativus, six were found to exert a slight inhibition on plant growth. Aiming to exploit their scaffold as a model for the synthesis of new compounds targeting photosynthesis, nine new rubrolide analogues were prepared. The synthesis was accomplished in 2-4 steps with a 10-39% overall yield from 3,4-dichlorofuran-2(5H)-one. All compounds were evaluated for their ability to inhibit the whole Hill reaction or excluding photosystem I (PSI). Several natural rubrolides and their analogues displayed good inhibitory potential (IC50 = 2-8 μM). Molecular docking studies on the photosystem II-light harvesting complex II (PSII-LHCII supercomplex) binding site were also performed. Overall, data support the use of rubrolides as a model for the development of new active principles targeting the photosynthetic electron transport chain to be used as herbicides.


Design and Synthesis of Eugenol Derivatives Bearing a 1,2,3-Triazole Moiety for Papaya Protection against Colletotrichum gloeosporioides
Ângela Maria Almeida lima, Luíza Carvalheira Moreira, Poliana Rodrigues Gazolla, Mariana Belizario Oliveira, Róbson Ricardo Teixeira, Vagner Tebaldi Queiroz, Matheus Ricardo Rocha, Willian Bucker Moraes, Nayara Araújo dos Santos, Wanderson Romão,et al.
American Chemical Society (ACS)
A series of 19 novel eugenol derivatives containing a 1,2,3-triazole moiety was synthesized via a two-step process, with the key step being a copper(I)-catalyzed azide-alkyne cycloaddition reaction. The compounds were assessed for their antifungal activities against Colletotrichum gloeosporioides, the causative agent of papaya anthracnose. Triazoles 2k, 2m, 2l, and 2n, at 100 ppm, were the most effective, reducing mycelial growth by 88.3, 85.5, 82.4, and 81.4%, respectively. Molecular docking calculations allowed us to elucidate the binding mode of these derivatives in the catalytic pocket of C. gloeosporioides CYP51. The best-docked compounds bind closely to the heme cofactor and within the channel access of the lanosterol (LAN) substrate, with crucial interactions involving residues Tyr102, Ile355, Met485, and Phe486. From such studies, the antifungal activity is likely attributed to the prevention of substrate LAN entry by the 1,2,3-triazole derivatives. The triazoles derived from natural eugenol represent a novel lead in the search for environmentally safe agents for controlling C. gloeosporioides.


Chemical Composition and Content of Essential Oil from Cultivated Bald Cypress (Taxodium distichum L.)
Seyyed Khalil Hosseinihashemi, Sayed Khosrow Hosseinashrafi, Mehrnoush Kelkian, Zohreh Shafighi, and Luiz Claudio Almeida Barbosa
BioResources
The essential oils extracted from the cone scale (CS), seed (SE), and thin branch with leaf (BL) of Taxodium distichum harvested during the winter season were analyzed by gas chromatography-mass spectrometry. Up to 37 components were identified, accounting for more than 96% of the total oil volume in all samples. Monoterpenes (CS 93.4%, SE 85.2%, and BL 72.8%) represented the major constituents of the essential oils, followed by smaller quantities of sesquiterpenoids. Monoterpene hydrocarbons (MH) dominated, with limonene (CS 56.5%, SE 50.5%, and BL 43.8%) and α-pinene (CS 31.7%, SE 26.1%, and BL 16.2%) being the main constituents. Representative minor constituents in the CS oil are camphene (1.3%) and bornyl acetate (2.6%); in the SE oil, β-myrcene (1.7%) and bornyl acetate (5.1%) were found; and in BL essential oil, β-myrcene (3.1%) and bornyl acetate (6%). Sesquiterpene hydrocarbons (CS 4.6%, SE 7.8%, and BL 12.9%) were the other major subclasses of components, with caryophyllene (CS 4.1%, SE 6.8%, and BL 9.3%) as the main constituent. The only oxygen-containing sesquiterpene found was caryophyllene oxide (CS 1.5%, SE 5.5%, and BL 8.3%). The compounds could be of great interest in food, cosmetics, and pharmaceutical applications.


Conchocarpus J. C. Mikan (Rutaceae): Chemical Constituents and Biological Activities
Anderson R. Santos, Vanderlúcia F. de Paula, and Luiz C. A. Barbosa
Wiley
AbstractRutaceae Juss. stands out as a botanical family recognized for its remarkable diversity in taxonomy, worldwide distribution, chemical composition, and biological activity exhibited by its compounds. Conchocarpus J. C. Mikan is one of the main genera of this family, comprising 50 species distributed throughout the Neotropical America. Brazil is the main center of diversity for this genus, hosting 66 % of the species as endemic. This is the first review concerning the genus Conchocarpus, emphasizing its chemical composition and biological activities. The selected papers for this review cover studies on 11 species, of which were identified 88 compounds. Among these, quinoline and acridone alkaloids predominate (57 %), followed by flavonoids, amides, coumarins and terpenoids. The biological activities of extracts and compounds indicate trypanocidal and leishmanicidal actions, as well as cytotoxic, fungicidal, molluscicidal, insecticidal, anticholinesterase and antioxidant activities.


Design, synthesis, docking studies and bioactivity evaluation of 1,2,3-triazole eugenol derivatives
Thiago Antonio de Sousa Cutrim, Fernando Fontes Barcelos, Leandra Martins Meireles, Poliana Aparecida Rodrigues Gazolla, Ângela Maria Almeida Lima, Róbson Ricardo Teixeira, Luiza Carvalheira Moreira, Vagner Tebaldi de Queiroz, Luiz Cláudio Almeida Barbosa, Pedro Alves Bezerra Morais,et al.
Informa UK Limited
Aim: The design, synthesis, docking studies and evaluation of the in vitro antifungal and cytotoxic properties of eugenol (EUG) containing 1,2,3-triazole derivatives are reported. Most of the derivatives have not been reported.Materials & methods: The EUG derivatives were synthesized, molecular docked and tested for their antifungal activity.Results: The compounds showed potent antifungal activity against Trichophyton rubrum, associated with dermatophytosis. Compounds 2a and 2i exhibited promising results, with 2a being four-times more potent than EUG. The binding mode prediction was similar to itraconazole in the lanosterol-14-α-demethylase wild-type and G73E mutant binding sites. Additionally, the pharmacokinetic profile prediction suggests good gastrointestinal absorption and potential oral administration.Conclusion: Compound 2a is a promising antifungal agent against dermatophytosis caused by T. rubrum.


Effects of Synthetic Tetronamides and Methylated Denigrins on Bacterial Quorum Sensing and Biofilm Formation
Sweta Roy, Jaime A. M. Acosta, Milandip Karak, Isabela Ramirez-Velez, Kohei Torikai, Dacheng Ren, and Luiz C. A. Barbosa
American Chemical Society (ACS)
Detrimental biofilms of bacterial pathogens cause chronic infections with a high-level tolerance to antibiotics. To identify new control agents, we synthesized and tested a total of 14 tetronamides (including 5 new compounds) and 6 denigrin intermediates on the model species Escherichia coli. At a concentration of 50 μg/mL, two tetronamides and two methylated denigrins exhibited significant inhibitory effects against biofilm formation of E. coli RP437, e.g., by 60 and 94%, respectively. Structural analysis of the tested compounds revealed that p-methoxybenzylidene and p-methoxyphenethyl moieties of denigrins are important for biofilm inhibition, while the former group is also essential to the activity against quorum sensing (QS) via AI-2. Specifically, tetramethyldenigrin B has strong inhibitory effects against both E. coli biofilm formation and AI-2-mediated QS and thus provides a promising lead structure for designing better control agents. Consistently, tetramethyldenigrin B also showed inhibitory activity against biofilm formation of uropathogenic E. coli. Together, these findings provide new insights for the rational design of novel biofilm and QS inhibitors.


Rubrolide analogues as urease inhibitors
Jodieh Oliveira Santana Varejão, Luiz Cláudio Almeida Barbosa, Eduardo Vinícius Vieira Varejão, Nidia Magally Galdámez Coreas, Vinicius Stefano Santos Morais, André Mauricio de Oliveira, Rosimeire Coura Barcelos, Célia Regina Álvares Maltha, and Luzia Valentina Modolo
Springer Science and Business Media LLC



Chemical composition and larvicidal activity of essential oils of three Artemisia species
Paula Tatiana Lopes Seixas, Antonio Jacinto Demuner, Luiz Claudio Almeida Barbosa, Cristiane Isaac Cerceau, Daiane Einhardt Blank, Marcelo Henrique Dos Santos, Elizeu de Sá Farias, and Marcelo Coutinho Picanço
Wiley



Removing phorbol esters from the biomass to add extra value to the byproduct from deoiling seeds of Jatropha curcas in the biodiesel industry
Dayana A. Rodrigues, Antonio J. Demuner, Luiz C. A. Barbosa, Gustavo A. M. Pereira, José D. Fabris, Félix G. de Siqueira, Márcio T. Pereira, Abelardo Silva Junior, and Otávio V. Carvalho
Springer Science and Business Media LLC



Powerful antioxidants within Cupressus arizonica Greene female cones and leaves essential oil
Seyyed Khalil Hosseinihashemi, Fatemeh Barzegari, Hadi Baseri, and Luiz Claudio Almeida Barbosa
Informa UK Limited
The composition and antioxidant activity of the essential oil obtained from the female cones and leaves of Cupressus arizonica were assessed using the DPPH assay. The total oil yields obtained through hydrodistillation from the female cones and leaves were 1.9% (v/w) and 0.65% (v/w), respectively. The GC-MS chemical analysis of the oils from the female cones and leaves resulted in the identification of 17 and 45 compounds, respectively. Moreover, the essential oils obtained from C. arizonica female cones were predominantly composed of monoterpene hydrocarbons, with α-pinene being the most abundant component at 72.20%. In contrast, the oil extracted from the leaves was rich in oxygenated monoterpenes, particularly umbellulone (17.33%). The oils extracted from the leaves exhibited remarkable DPPH radical scavenging activity, displaying a value of 95.6%. This value was comparable to that of ascorbic acid (99.6%) and BHT (96.9%) when tested at a concentration of 59 mg/mL.


New amides derived from sclareolide as anticholinesterase agents
Júnio G. Silva, Tatiane F. Borgati, Samuel M.G. Lopes, Niels Heise, Sophie Hoenke, René Csuk, and Luiz C.A. Barbosa
Elsevier BV



Natural and synthetic inhibitors of photosynthesis light reactions




Montmorillonite K10 Clay Catalyzed Synthesis of Novel β-Aminocarbonyl Compounds and Their Biological Evaluation
Gottimukkala Rambabu, Yarragudi Bathal Reddy Kiran, Yadamari Tarakeswar, Shaik Ibrahim Khalivulla, Luiz Claudio Almeida Barbosa, and Vijayaparthasarathi Vijayakumar
Wiley
An efficient and reusable green catalyst for the synthesis of β-aminocarbonyl compounds has been developed. In this new and greener approach, β-aminocarbonyl compounds (1a-1r) were obtained by Montmorillonite K10 clay catalyzed reaction of aryl amines, aliphatic/aromatic aldehydes and β-ketoesters. Molecular docking investigations were performed for all compounds (1a-1r) with the proteins PDB ID: 1JIJ and 1KZN for S. aureus and E. coli, respectively. For all compounds good to strong interactions with the active sites were observed. The biological activities of β-aminocarbonyl compounds were further assessed for their antibacterial and antioxidant activities. The results confirmed that β-aminocarbonyl compounds could be further developed into new drugs with potent antibacterial and antioxidant activities.


Synthesis and medicinal chemistry of tetronamides: Promising agrochemicals and antitumoral compounds
Júnio G. Silva, Amanda S. de Miranda, Fyaz M.D. Ismail, and Luiz C.A. Barbosa
Elsevier BV



Functionalization of poly(lactic-co-glycolic acid) nanofibrous membranes with antibiofilm compounds
Thaise C. Geremias, Marcos A. Batistella, Ricardo R. S. Magini, Selene M. A. Guelli U. de Souza, Cesar V. Franco, Luiz C. A. Barbosa, Ulisses A. Pereira, Juan P. Hinestroza, Andréa L. Pimenta, and Antônio A. Ulson de Souza
Wiley



Cadiolide analogues and their precursors as new inhibitors of bacterial quorum sensing and biofilm formation
Thais A. Moreira, Isabel V. Antolínez, Wagner O. Valença, Sweta Roy, Isabela Ramirez, Luiz C.A. Barbosa, and Dacheng Ren
Elsevier BV



Asymmetric Transfer Hydrogenation of Aryl Heteroaryl Ketones using Noyori-Ikariya Catalysts
Ye Zheng, Jaime A. Martinez‐Acosta, Mohammed Khimji, Luiz C. A. Barbosa, Guy J. Clarkson, and Martin Wills.
Wiley



Caryocar brasiliense Camb. fruits from the Brazilian Cerrado as a rich source of carotenoids with pro-vitamin A activity
Katalin C. Geöcze, Luiz C.A. Barbosa, Cláudio F. Lima, Mário G. Ferruzzi, Paulo H. Fidêncio, Helena M.P. Sant’ana, and Flaviano O. Silvério
Elsevier BV
Abstract Caryocar brasiliense Camb. is the best-known fruit of the Brazilian Cerrado. This fruit has yellow pulp containing several carotenoids and has a strong and exotic flavor; however, its composition may vary due to factors such as genotypic differences, seasonality, cultivation forms, climatic and soil characteristics, maturation stage, type of storage and processing. Therefore, the present study aimed to determine the chemical composition of carotenoids with pro-vitamin A activity of C. brasiliense fruits from 18 Brazilian municipalities. The vitamin A value expressed as μg Retinol Activity Equivalent (RAE) in the fresh fruit and carotenoid profile were determined by high-performance liquid chromatography coupled to a diode array detector (HPLC- DAD). The main carotenoids found were β-cryptoxanthin and β-carotene. High variation in vitamin A values were observed, especially among the fruits from Gato-Preto-MA with (1.4 µg RAE/100 g fresh fruit) and Januaria-MG (719 µg RAE/100 g fresh fruit). PC1 and PC2 explored about 98.80% of the data variance in the multivariate analysis, Principal Component Analysis (PCA) and Hierarchical Cluster Analysis (HCA) and organized the C. brasiliense fruits in three clusters by decreasing vitamin A values. The fruits from the municipalities of Januaria, Japonvar, Arinos, Salinas and Montes Claros showed higher carotenoid content.


Acetic Acid-Mediated Synthesis of Kojic Acid Derivatives
Y. B. Kiran, G. Rambabu, V. Vijayakumar, and L. C. A. Barbosa
Pleiades Publishing Ltd
A green acetic acid-mediated synthesis of kojic acid derivatives through a multicomponent reaction (MCR) has been developed. This new protocol is simple and efficient; it involves a one-pot reaction of equimolar amounts of kojic acid, aromatic aldehydes, and several active methylene compounds at 90°C in 3 h and results in the formation of a wide range of kojic acid derivatives with high yields. Furthermore, the formation of acyclic product when only kojic acid reacted with benzaldehyde under similar reaction conditions has been explored.


Antibacterial and Cytotoxic Activity of Ruthenium-p-cymene Complexes with 2-Methylquinolin-8-ol Derivatives
Amalyn Nain‐Perez, Luiz C. A. Barbosa, Maria H. Araujo, João P. A. Martins, Jacqueline A. Takahashi, Geane Oliveira, Renata Diniz, Lucie Heller, Sophie Hoenke, and René Csuk
Wiley



A new tropane alkaloid and other metabolites from Erythroxylum macrocalyx (Erythroxylaceae) and their antiproliferative activities
Lauro J.C. da Silva, Léia A. Alves, Valdenizia R. Silva, Luciano S. Santos, Daniel P. Bezerra, Milena B.P. Soares, Antonio C. Doriguetto, Luiz C.A. Barbosa, Jeferson C. do Nascimento, Guadalupe E.L. Macedo,et al.
Elsevier BV
Abstract A new tropane alkaloid 7β-acetoxy-6β-benzoyloxy-3α-hydroxytropane (1) was isolated from the twigs of Erythroxylum macrocalyx Mart. (Erythroxylaceae), along with the known substances: 6β,7β-dibenzoyloxy-3α-hydroxytropane (2), 6β,7β-dihydroxy-3α-(phenylacetoxy)tropane (3), 3α-benzoyloxy-6β,7β-dihydroxytropane (4), 6β-benzoyloxy-3α-(4-hydroxy-3,5-dimetoxybenzoyloxy)tropane (5), ombuin-3-rutinoside-5-glucoside (6), lupeol (7), taraxerol (8) and lupenone (9). Compounds 1 and 2 were also isolated from the leaves. The structures were established by analyses of 1D- and 2D-NMR and MS data, as well as by comparison with literature data for known compounds. The structure of 2 was also supported by X-ray crystallography analyses. The compounds were evaluated in vitro for their antibacterial and antiproliferative activities. Compound 5 showed high antiproliferative activity on liver hepatocellular carcinoma cells (HepG2) with IC50 value of 3.66 μg mL−1 (8.29 μmol L-1), but no cytotoxic effect (IC50 > 25 μg mL-1) on human lymphoblast cell line. This study reveals the potential use of 5 as prototype for the synthesis of new antiproliferative agents.


Comparative study of five Artemisia species submmited to different doses of mineral fertilization.




Composition proximate, bioactive compounds and antioxidant capacity of Butia capitata
Maria Cristina de Albuquerque BARBOSA, Queila da Silva ROSA, Leandro de Morais CARDOSO, Antônio Frederico de Freitas GOMIDES, Luiz Cláudio de Almeida BARBOSA, Helena Maria Pinheiro SANT’ANNA, Soraia Silva PINHEIRO, Maria do Carmo Gouveia PELUZIO, Reinaldo Duque Brasil Landulfo TEIXEIRA, and Maria Anete Santana VALENTE
FapUNIFESP (SciELO)
Fruit consumption by humans is recognized to be important because it provides nutrients and bioactive compounds that contribute to reducing the risk of developing various diseases, including non-communicable diseases and chronic diseases (Slavin & Lloyd, 2012). In this context, several fruits underutilized in human food have been receiving special attention from the scientific community as a source of nutrients, bioactive compounds and due to their nutritional and functional properties.

RECENT SCHOLAR PUBLICATIONS

Synthesis and structure-activity relationships of novel biphenyl containing tetronamides with cyanobactericidal activity
JG Silva, AS de Miranda, D Szczerbowski, AM de Oliveira, G Forlani, ...
Journal of Molecular Structure 1321, 139848 2025



Conchocarpus J. C. Mikan (Rutaceae): Chemical Constituents and Biological Activities
AR Santos, VF de Paula, LCA Barbosa
Chemistry & Biodiversity 22 (2), e202402119 2025



JOS ISRAEL VARGAS: ESSENCES OF THE LIFE AND WORK OF A SCIENCE LEADER IN BRAZIL
LCA Barbosa, LE Faria, JD Fabris
Qumica Nova 48, e-20250087 2025



JOS ISRAEL VARGAS: ESSNCIAS DA VIDA E OBRA DE UM LDER DA CINCIA NO BRASIL
LCA Barbosa, LE Faria, JD Fabris
Qumica Nova 48 (3), e-20250087 2025



HUMPHRY DAVY NAS PGINAS DE PERIDICOS BRASILEIROS DO INCIO DO SCULO XIX
LCA Barbosa, PGM Gomes, CAL Figueiras
Qumica Nova 48 (2), e-20250076 2025



HUMPHRY DAVY ON THE PAGES OF BRAZILIAN EARLY-NINETEENTH CENTURY PUBLICATIONS.
LCA Barbosa, PGM Gomes, CAL Figueiras
QUIMICA NOVA 48 (2) 2025



A Qumica nos primrdios de Belo Horizonte: Sujeitos e Instituies Pioneiras na Capital Mineira
RRC Silva, LC de Almeida Barbosa, CAL Filgueiras
Revista Eletrnica Histria em Reflexo 20 (38), 376-405 2024



Antibiofilm effect of rubrolide analogues and derived lactams on single-species biofilms
BB Passoni, ER Herrero, EB Magini, A de Lima Pimenta, LCA Barbosa, ...
Journal of Molecular Structure 1313, 138616 2024



ANLISE DO PERFIL CLNICO DE PACIENTES COM LEUCEMIA MIELOIDE CRNICA NO AMAZONAS
LMS Souza, MGS Vasconcelos, KKR Gomes, VC Costa, ...
Hematology, Transfusion and Cell Therapy 46, S480-S481 2024



CASO RARO DE LEUCEMIA LINFOBLSTICA AGUDA B COM TRANSLOCAO BCR:: ABL1 P190 E VARIANTE FLT3-ITD EM PACIENTE DE MANAUS, AMAZONAS
ROD Santos, NP Garcia, LCA Barbosa, WO Azevedo, AMA Marrie, ...
Hematology, Transfusion and Cell Therapy 46, S370-S371 2024



Design, synthesis, docking studies and bioactivity evaluation of 1, 2, 3-triazole eugenol derivatives
TA de Sousa Cutrim, FF Barcelos, LM Meireles, PA Rodrigues Gazolla, ...
Future Medicinal Chemistry 16 (18), 1883-1897 2024



Natural rubrolides and their synthetic congeners as inhibitors of the photosynthetic electron transport chain
M Karak, JAM Acosta, HF Cortez-Hernandez, JL Cardona, G Forlani, ...
Journal of Natural Products 87 (9), 2272-2280 2024



Design and Synthesis of Eugenol Derivatives Bearing a 1,2,3-Triazole Moiety for Papaya Protection against Colletotrichum gloeosporioides
AM Almeida lima, LC Moreira, PR Gazolla, MB Oliveira, RR Teixeira, ...
Journal of Agricultural and Food Chemistry 72 (22), 12459-12468 2024



Chemical composition and content of essential oil from cultivated bald cypress (Taxodium distichum L.)
SK Hosseinihashemi, SK Hosseinashrafi, M Kelkian, Z Shafighi, ...
BioResources 19 (1), 751 2024



Powerful antioxidants within Cupressus arizonica Greene female cones and leaves essential oil
SK Hosseinihashemi, F Barzegari, H Baseri, LCA Barbosa
Natural Product Research, 1-10 2023



Effects of Synthetic Tetronamides and Methylated Denigrins on Bacterial Quorum Sensing and Biofilm Formation
S Roy, JAM Acosta, M Karak, I Ramirez-Velez, K Torikai, D Ren, ...
ACS omega 8 (41), 37798-37807 2023



Rubrolide analogues as urease inhibitors
JOS Varejo, LCA Barbosa, EVV Varejo, NMG Coreas, VSS Morais, ...
Monatshefte fr Chemie-Chemical Monthly 154 (10), 1177-1187 2023



ANALYSIS OF THE ESSENTIAL OIL OF ARTEMISIA ABSINTHIUM IN TWO HARVEST TIMES.
PT Lopes Seixas, A Jacinto Demuner, H Guilhon de Castro, ...
Revista Foco (Interdisciplinary Studies Journal) 16 (3) 2023



ANALYSIS OF THE ESSENTIAL OIL OF ARTEMISIA ABSINTHIUM IN TWO HARVEST TIMES
PTL Seixas, AJ Demuner, HG de Castro, LCA Barbosa
REVISTA FOCO 16 (3), e1224-e1224 2023



Chemical composition and larvicidal activity of essential oils of three Artemisia species
PTL Seixas, AJ Demuner, LCA Barbosa, CI Cerceau, DE Blank, ...
Journal of Applied Entomology 147 (2), 116-125 2023

MOST CITED SCHOLAR PUBLICATIONS

Phenolic compounds and antioxidant capacity of Brazilian mango (Mangifera indica L.) varieties
SMR Ribeiro, LCA Barbosa, JH Queiroz, M Kndler, A Schieber
Food chemistry 110 (3), 620-626 2008
Citations: 519



Espectroscopia no infravermelho: na caracterizao de compostos orgnicos
LC de Almeida Barbosa
Ed. UFV 2007
Citations: 395



Chemical Variability and Biological Activities of Eucalyptus spp. Essential Oils
LCA Barbosa, CA Filomeno, RR Teixeira
Molecules 21 (12), 1671 2016
Citations: 270



Evaluation of the Chemical Composition of Brazilian Commercial Cymbopogon citratus (D.C.) Stapf Samples
LCA Barbosa, UA Pereira, AP Martinazzo, CR Maltha, RR Teixeira, ...
Molecules 13 (8), 1864-1874 2008
Citations: 200



Seasonal variation in the composition of volatile oils from Schinus terebinthifolius Raddi
LCA Barbosa, AJ Demuner, AD Clemente, VF Paula, F Ismail
Qumica Nova 30, 1959-1965 2007
Citations: 199



Recent mechanistic developments and next generation catalysts for the Sonogashira coupling reaction
M Karak, LCA Barbosa, GC Hargaden
Rsc Advances 4 (96), 53442-53466 2014
Citations: 171



Plant compounds insecticide activity against Coleoptera pests of stored products
MD Moreira, MC Picano, LCA Barbosa, RNC Guedes, MR Campos, ...
Pesquisa Agropecuria Brasileira 42, 909-915 2007
Citations: 167



Synthesis and insecticidal activity of new amide derivatives of piperine
VF Paula, LCA Barbosa, AJ Demuner, D Pil‐Veloso, MC Picano
Pest Management Science 56 (2), 168-174 2000
Citations: 155



Chemical composition and antibacterial activity of essential oils from verbenaceae species: alternative sources of (E)-caryophyllene and germacrene-D
RM Montanari, LCA Barbosa, AJ Demuner, CJ Silva, LS Carvalho, ...
Qumica Nova 34, 1550-1555 2011
Citations: 139



Compounds from Ageratum conyzoides: isolation, structural elucidation and insecticidal activity
MD Moreira, MC Picanco, LCA Barbosa, RNC Guedes, EC Barros, ...
Pest Management Science: Formerly Pesticide Science 63 (6), 615-621 2007
Citations: 132



Determination of Eucalyptus spp lignin S/G ratio: A comparison between methods
CA Nunes, CF Lima, LCA Barbosa, JL Colodette, AFG Gouveia, ...
Bioresource technology 101 (11), 4056-4061 2010
Citations: 125



Seasonal Variation in the Chemical Composition and Antimicrobial Activity of Volatile Oils of Three Species of Leptospermum (Myrtaceae) Grown in Brazil
AJ Demuner, LCA Barbosa, CG Magalhaes, CJ Da Silva, CRA Maltha, ...
Molecules 16 (2), 1181-1191 2011
Citations: 113



Dissolving pulp production from bamboo
LAR Batalha, JL Colodette, JL Gomide, LCA Barbosa, CRA Maltha, ...
BioResources 7 (1), 640-651 2012
Citations: 109



Chemical composition and antibacterial activities from the essential oils of Myrtaceae species planted in Brazil
CJ Silva, LCA Barbosa, AJ Demuner, RM Montanari, AL Pinheiro, I Dias, ...
Qumica Nova 33, 104-108 2010
Citations: 106



Introduo Qumica Orgnica
LCA Barbosa
Pearson Prentie Hall 2011
Citations: 104



Os pesticidas, o homem eo meio ambiente
LC de Almeida Barbosa
UFV 2004
Citations: 98



Antibacterial Activity of the Alkaloid-Enriched Extract from Prosopis juliflora Pods and Its Influence on in Vitro Ruminal Digestion
ET Dos Santos, MLA Pereira, CFPG Da Silva, LC Souza-Neta, R Geris, ...
International journal of molecular sciences 14 (4), 8496-8516 2013
Citations: 95



Determinao da relao siringila/guaiacila da lignina em madeiras de eucalipto por pirlise acoplada cromatografia gasosa e espectrometria de massas (PI CG/EM)
LCA Barbosa, CRA Maltha, VL Silva, JL Colodette
Qumica Nova 31, 2035-2041 2008
Citations: 94



Comparative study of the essential oils of seven Melaleuca (Myrtaceae) species grown in Brazil
CJ Silva, LCA Barbosa, CRA Maltha, AL Pinheiro, FMD Ismail
Flavour and fragrance journal 22 (6), 474-478 2007
Citations: 91



Influncia da temperatura do ar de secagem sobre o teor e a composio qumica do leo essencial de Lippia alba (Mill) NE Brown
FF Barbosa, LCA Barbosa, EC Melo, FM Botelho, RHS Santos
Qumica Nova 29, 1221-1225 2006
Citations: 91