Dr. Zimarino is a clinical and interventional cardiologist, with >30 years of working experience in Italy, France, USA, and Canada.
He has been invited as faculty in major international and national clinical and interventional cardiology congresses.
He edited 3 monographs, and coauthored 12 chapters of books in Italian, English, and French.
He has >180 manuscripts currently referenced on Pubmed.
He is the director of CCU and Cardiology Department at "SS. Annunziata" Hospital in Chieti (ASL 2 Abruzzo).
EDUCATION
1982-1988 School and Degree in Medicine at the “G. d’Annunzio” University - Chieti (Italy)
1988-1992 Resident in Cardiology at "Alma Mater” University - Bologna (Italy)"
1992-1993 Fellow in Interventional Cardiology at Parly 2 (Paris, France)
2003-2006 PhD at the "G. d’Annunzio” University - Chieti (Italy)
RESEARCH INTERESTS
Marco Zimarino performs coronary intervention (particular interest in imaging, complex lesions, and adjunctive drug treatment) and structural intervention (aortic and mitral valve, closure of PFO).
Prognostic Role and Therapeutic Implications of Intravascular Optical Coherence Tomography Detected Coronary Plaque Microstructures in Patients with Coronary Artery Disease Michele Russo, Elena Bacigalupi, Francesco Radico, Luca Scorpiglione, Filippo Luca Gurgoglione, et al. Journal of Clinical Medicine, 2025 Intracoronary optical coherence tomography (OCT) is a highly accurate and sensitive imaging tool capable of providing high resolution visualization of atherosclerotic coronary plaque morphology and microstructures in vivo. OCT has proven to be useful in clinical practice, particularly in percutaneous coronary intervention (PCI) guidance, assessment of stent-related complications, and elucidation of the pathobiological cause of acute coronary syndrome. Notably, OCT allows for the detection of specific plaque features (i.e., thin cap fibroatheroma, lipid-rich plaque, macrophage infiltration, healed plaques, microvessels, etc.) that are known to carry prognostic significance in the context of coronary artery disease (CAD). These insights may offer valuable information about the patient’s overall atherosclerotic background, potentially supporting more personalized secondary prevention strategies, including lifestyle modification and targeted pharmacologic therapies. Recently, the role of preventive PCI in plaques with high-risk features has also been investigated with promising—though still preliminary—results. In this narrative review, we primarily aim to discuss studies evaluating the prognostic value of OCT-identified coronary plaque microstructures. We also assessed potential therapeutic implications in the management of patients with CAD.
Ultra-Short Term Evaluation of Coronary Vessel Wall Changes in Reference Segments Adjacent to Culprit Lesions in ST-Segment Elevation Myocardial Infarction Journal of Invasive Cardiology, 2021
Is complete revascularisation mandated for all patients with multivessel coronary artery disease? Carlo De Innocentiis, Institute of Cardiology and Centre of Excellence on Ageing, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy, Marco Zimarino, Institute of Cardiology and Centre of Excellence on Ageing, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy, Raffaele De Caterina, et al. Interventional Cardiology Reviews Research Resources, 2018
Localizing factors in atherosclerosis Irene Pescetelli, Marco Zimarino, Angelo Ghirarduzzi, Raffaele De Caterina Journal of Cardiovascular Medicine, 2015
The optimal time window for percutaneous coronary intervention in thrombolysis-treated ST-elevation myocardial infarction Giornale Italiano Di Cardiologia, 2010
Vulnerable plaque imaging: Is it time for its application in clinical practice? Giornale Italiano Di Cardiologia, 2010
QT dispersion and myonecrosis after stent percutaneous coronary intervention Italian Heart Journal Supplement Official Journal of the Italian Federation of Cardiology, 2004
Influence of device selection on angiographic outcomes for the treatment of in-stent restenosis. A sub analysis from the Washington Radiation for In-Stent Restenosis Trial (WRIST) Italian Heart Journal, 2002
Magnetocardiography: Current status and perspectives. Part I: Physical principles and instrumentation Italian Heart Journal, 2002
Magnetocardiography: Current status and perspectives. Part II: Clinical applications Italian Heart Journal, 2002
Endothelial cell transfections: a way for studying promoter activity of genes involved in atherogenesis. Italian Heart Journal Official Journal of the Italian Federation of Cardiology, 2000
Rescue coronary angioplasty: a crotch for limping thrombolysis? Cardiologia Rome Italy, 1999
Single coronary artery with a right origin: angiography identification of the R-II subgroup Cardiologia Rome Italy, 1999
Color duplex scanning for the identification of extracranial atherosclerosis in patients with suspected coronary artery disease. Cardiologia Rome Italy, 1999
Carotid atherosclerosis in patients with suspected coronaropathy: Relationship with traditional risk factors in the two vascular districts Giornale Italiano Di Cardiologia, 1999
Percutaneous coronary angioplasty of radial artery conduits Giornale Italiano Di Cardiologia, 1998
Bail-out of stent jail: Stent delivery through stent struts Journal of Invasive Cardiology, 1996
Right coronary artery subselective angiography with a 5-French catheter mimicking a coronary arteriovenous fistula American Journal of Cardiac Imaging, 1995
Adjustment of pulmonary capillary wedge pressure for wave delay increases the accuracy of mitral valve area measurement Journal of Heart Valve Disease, 1995
Coronary angioplasty during acute myocardial infarction Giornale Italiano Di Cardiologia, 1995
Multi-instrumental revascularization adjusted to the coronary lesions (MIRACLE). The role of new technologies Archives Des Maladies Du Coeur Et Des Vaisseaux, 1995
Short-term efficacy of high speed rotational atherectomy with and balloon angioplasty in the treatment of lesions located at the ostium of a coronary branch Cardiologia Rome Italy, 1994
Preliminary experience in the treatment of complex stenosis in the aged (> or = 70 years) with high-speed rotational atherotomy followed by conventional PTCA Giornale Italiano Di Cardiologia, 1994
Comparison between transthoracic and transesophageal echocardiography in the evaluation of candidates to percutaneous mitral valvuloplasty Cardiologia Rome Italy, 1994
Tandem balloon angioplasty X. Favereau, T. Corcos, M. Zimarino, G. Souffrant Catheterization and Cardiovascular Diagnosis, 1993
Role of the different percutaneous revascularization techniques in single and multivessel coronary artery disease. Cardiologia Rome Italy, 1993
Chest roentgenology and angiography of the ischemic heart disease Rays International Journal of Radiological Sciences, 1993
The 24-hour hemodynamic changes after percutaneous mitral valvuloplasty Cardiologia Rome Italy, 1993
Critical mitral stenosis in pregnancy: description of a case treated with percutaneous valvuloplasty Cardiologia Rome Italy, 1992