Syeda Mahwish Bakht

@uminho.pt

PhD. Student
I3Bs - Research Institute on Biomaterials, Biodegradables and Bi



                    

https://researchid.co/mahwishbakht

Experienced Associate Researcher in fabrication of a tubular polydimethylsiloxane (PDMS) platform for modeling blood vessels in vitro for organ/tissue on chip applications. Currently working on developing innovative strategies utilizing natural materials for development of microchips via additive manufacturing and microfluidics techniques to generate physiologically relevant in-vitro tissue models for disease modeling and drug testing applications.

EDUCATION

2017-Present: 3Bs Research Group, University of Minho, Portugal.
Research Degree Ph.D. Field of study: Tissue Engineering Regenerative Medicine

2013-2016: COMSATS Institute of Information and Technology, Abbottabad, Pakistan
Research Degree M. Phil Field of study: Pharmaceutical Sciences 1st Division

2008-2013: COMSATS Institute of Information and Technology, Abbottabad, Pakistan Professional Degree Doctor of Pharmacy 1st Division

RESEARCH INTERESTS

3D/Bioprinting, Microfluidics, Organ/Tissue on chip, Disease Modeling and Drug testing

1652

Scholar Citations

10

Scholar h-index

11

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Human Tendon‐on‐Chip: Unveiling the Effect of Core Compartment‐T Cell Spatiotemporal Crosstalk at the Onset of Tendon Inflammation
    SM Bakht, A Pardo, M Gomez‐Florit, D Caballero, SC Kundu, RL Reis, ...
    Advanced Science 11 (41), 2401170 2024

  • Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell‐Scale Biophysical Cues in Bioengineered Constructs (Adv. Funct. Mater. 29/2024)
    SPB Teixeira, A Pardo, SM Bakht, M Gomez‐Florit, RL Reis, ME Gomes, ...
    Advanced Functional Materials 34 (29), 2470162 2024

  • Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell‐Scale Biophysical Cues in Bioengineered Constructs
    SPB Teixeira, A Pardo, SM Bakht, M Gomez‐Florit, RL Reis, ME Gomes, ...
    Advanced Functional Materials, 2312961 2024

  • 3D WRITING OF MULTICELLULAR TENDON-ON-CNC-CHIP MODELS
    RF Monteiro, SM Bakht, M Gomez-Florit, RL Reis, ME Gomes, ...
    Orthopaedic Proceedings 106 (SUPP_2), 15-15 2024

  • 3D BIOMIMETIC CONSTRUCTS STEER STEM CELL COMMITMENT BY SYNERGISTIC MODULATION OF BIOPHYSICAL CUES AND GROWTH FACTOR SIGNALLING
    SPB Teixeira, A Pardo, SM Bakht, M Gomez-Florit, RL Reis, ME Gomes, ...
    Orthopaedic Proceedings 106 (SUPP_1), 13-13 2024

  • COMBINING MAGNETICALLY ASSISTED AND MATRIX-ASSISTED 3D BIOPRINTING FOR ANISOTROPIC TISSUE ENGINEERING
    SM Bakht, A Pardo, RL Reis, RMA Domingues, ME Gomes
    Orthopaedic Proceedings 106 (SUPP_2), 59-59 2024

  • MIRNA-LADEN MAGNETIC-RESPONSIVE BIOINK FOR TENDON AND ENTHESIS TISSUE ENGINEERING
    CJP Silva, R Dominguez, SM Bakht, A Pardo, V Joris, AI Gonalves, ...
    Orthopaedic Proceedings 106 (SUPP_2), 74-74 2024

  • Innovative approaches to the use of nanotools for creating tendon tissue-mimetic constructs and disease models
    SM Bakht
    2023

  • Automated Biofabrication of Multicellular Human Tendon Microphysiological Systems Within a Biomimetic Fibrillar Support Platform
    RF Monteiro, SM Bakht, MG Florit, RL Reis, ME Gomes, R Domingues
    TISSUE ENGINEERING PART A 29 (13-14) 2023

  • Bioinspired Hydrogels Promote Tenogenic Stem Cell Commitment by Synergistic Control over Topographical Cues and Growth Factor Signaling
    SPB Teixeira, A Pardo, SM Bakht, MG Florit, RL Reis, ME Gomes, ...
    TISSUE ENGINEERING PART A 29 (13-14) 2023

  • DIRECTING STEM CELL COMMITMENT IN 3D BIOINSPIRED HYDROGELS BY GROWTH FACTOR SEQUESTRATION USING MOLECULARLY IMPRINTED NANOPARTICLES
    SP Barbosa Teixeira, A Pardo, SM Bakht, M Gomez-Florit, RL Reis, ...
    TISSUE ENGINEERING PART A 29 (11-12), 860-861 2023

  • Writing 3D In Vitro Models of Human Tendon within a Biomimetic Fibrillar Support Platform
    RF Monteiro, SM Bakht, M Gomez-Florit, FC Stievani, ALG Alves, RL Reis, ...
    ACS Applied Materials & Interfaces 15 (44), 50598-50611 2023

  • Magnetically‐assisted 3D bioprinting of anisotropic tissue‐mimetic constructs
    A Pardo, SM Bakht, M Gomez‐Florit, R Rial, RF Monteiro, SPB Teixeira, ...
    Advanced Functional Materials 32 (50), 2208940 2022

  • Tendon derived extracellular matrix hydrogel for injection and bioprinting
    ALG Alves, FC Stievani, M Gomez-Florit, SM Bakht, JPH Pfeifer, ...
    Mary Ann Liebert, Inc 2022

  • 3D bioprinting of miniaturized tissues embedded in self‐assembled nanoparticle‐based fibrillar platforms
    SM Bakht, M Gomez‐Florit, T Lamers, RL Reis, RMA Domingues, ...
    Advanced Functional Materials 31 (46), 2104245 2021

  • Engineering next-generation bioinks with nanoparticles: moving from reinforcement fillers to multifunctional nanoelements
    SM Bakht, A Pardo, M Gmez-Florit, RL Reis, RMA Domingues, ...
    Journal of Materials Chemistry B 9 (25), 5025-5038 2021

  • Natural Materials
    M Gmez-Florit, RMA Domingues, SM Bakht, BB Mendes, RL Reis, ...
    Biomaterials Science, 361-375 2020

  • Perforated and Endothelialized elastomeric tubes for vascular modeling
    M Duchamp, SM Bakht, J Ju, IK Yazdi, W Zhang, YS Zhang
    Advanced materials technologies 4 (9), 1800741 2019

  • Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the inhibition of monoamine oxidases: Synthesis, in vitro biological evaluation and molecular
    N Abbas, S Zaib, SM Bakht, A Ibrar, I Khan, S Batool, A Saeed, J Iqbal
    Bioorganic Chemistry 70, 17-26 2017

  • Bioprinting: Rapid continuous multimaterial extrusion bioprinting (Adv. Mater. 3/2017)
    W Liu, YS Zhang, MA Heinrich, F De Ferrari, HL Jang, SM Bakht, ...
    Advanced Materials 29 (3) 2017

MOST CITED SCHOLAR PUBLICATIONS

  • 3D bioprinting for tissue and organ fabrication
    YS Zhang, K Yue, J Aleman, K Mollazadeh-Moghaddam, SM Bakht, ...
    Annals of biomedical engineering 45, 148-163 2017
    Citations: 743

  • Rapid continuous multimaterial extrusion bioprinting
    W Liu, YS Zhang, MA Heinrich, F De Ferrari, HL Jang, SM Bakht, ...
    Advanced materials 29 (3), 1604630 2017
    Citations: 465

  • Elastomeric free-form blood vessels for interconnecting organs on chip systems
    W Zhang, YS Zhang, SM Bakht, J Aleman, SR Shin, K Yue, M Sica, ...
    Lab on a Chip 16 (9), 1579-1586 2016
    Citations: 116

  • Synthesis, biological evaluation and molecular docking of N-phenyl thiosemicarbazones as urease inhibitors
    A Hameed, KM Khan, ST Zehra, R Ahmed, Z Shafiq, SM Bakht, M Yaqub, ...
    Bioorganic chemistry 61, 51-57 2015
    Citations: 83

  • Exploration of a library of triazolothiadiazole and triazolothiadiazine compounds as a highly potent and selective family of cholinesterase and monoamine oxidase inhibitors
    I Khan, SM Bakht, A Ibrar, S Abbas, S Hameed, JM White, UA Rana, ...
    RSC Advances 5 (27), 21249-21267 2015
    Citations: 51

  • Magnetically‐assisted 3D bioprinting of anisotropic tissue‐mimetic constructs
    A Pardo, SM Bakht, M Gomez‐Florit, R Rial, RF Monteiro, SPB Teixeira, ...
    Advanced Functional Materials 32 (50), 2208940 2022
    Citations: 46

  • Engineering next-generation bioinks with nanoparticles: moving from reinforcement fillers to multifunctional nanoelements
    SM Bakht, A Pardo, M Gmez-Florit, RL Reis, RMA Domingues, ...
    Journal of Materials Chemistry B 9 (25), 5025-5038 2021
    Citations: 39

  • 3D bioprinting of miniaturized tissues embedded in self‐assembled nanoparticle‐based fibrillar platforms
    SM Bakht, M Gomez‐Florit, T Lamers, RL Reis, RMA Domingues, ...
    Advanced Functional Materials 31 (46), 2104245 2021
    Citations: 34

  • Pyrazolobenzothiazine-based carbothioamides as new structural leads for the inhibition of monoamine oxidases: design, synthesis, in vitro bioevaluation and molecular docking
    SMA Abid, S Aslam, S Zaib, SM Bakht, M Ahmad, MM Athar, JM Gardiner, ...
    Medchemcomm 8 (2), 452-464 2017
    Citations: 24

  • Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the inhibition of monoamine oxidases: Synthesis, in vitro biological evaluation and molecular
    N Abbas, S Zaib, SM Bakht, A Ibrar, I Khan, S Batool, A Saeed, J Iqbal
    Bioorganic Chemistry 70, 17-26 2017
    Citations: 22

  • Writing 3D In Vitro Models of Human Tendon within a Biomimetic Fibrillar Support Platform
    RF Monteiro, SM Bakht, M Gomez-Florit, FC Stievani, ALG Alves, RL Reis, ...
    ACS Applied Materials & Interfaces 15 (44), 50598-50611 2023
    Citations: 10

  • Perforated and Endothelialized elastomeric tubes for vascular modeling
    M Duchamp, SM Bakht, J Ju, IK Yazdi, W Zhang, YS Zhang
    Advanced materials technologies 4 (9), 1800741 2019
    Citations: 7

  • Natural Materials
    M Gmez-Florit, RMA Domingues, SM Bakht, BB Mendes, RL Reis, ...
    Biomaterials Science, 361-375 2020
    Citations: 6

  • Prescribing Practice of Antibiotics Amongst Children; Physicians’ Behavior and Knowledge
    H Ullah, SA Khan, SM Bakht, Y Tehseen, S Karim, A Baseer, G Murtaza
    Lat. Am. J. Pharm 31 (9), 1367-9 2012
    Citations: 5

  • Guiding Stem Cell Tenogenesis by Modulation of Growth Factor Signaling and Cell‐Scale Biophysical Cues in Bioengineered Constructs
    SPB Teixeira, A Pardo, SM Bakht, M Gomez‐Florit, RL Reis, ME Gomes, ...
    Advanced Functional Materials, 2312961 2024
    Citations: 1

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

2020: Natural Materials Manuel Gómez-Florit,Rui M.A. Domingues,Syeda Mahwish Bakht,Bárbara B. Mendes,Rui L. Reis,Manuela E. Gomes
Biomaterials Science 1.3.6 Elsevier 2020 (10.1016/

2019: Perforated and Endothelialized Elastomeric Tubes for Vascular Modeling Margaux Duchamp, Syeda Mahwish Bakht, Jie Ju, Iman K. Yazdi, Weijia Zhang, and Yu Shrike Zhang Advanced Materials Technologies (

2016: Pyrazolobenzothiazine-based carbothioamides as new structural leads for the inhibition of monoamine oxidases: design, synthesis, in-vitro bioevaluation and molecular docking studies. Syed Mobasher Ali Abid, Sana Aslam, Sumera Zaib, Syeda Mahwish Bakht, Matloob Ahmad, Muhammad Makshoof Athar, John M. Gardiner and Jamshed Iqbal. Med. Chem. Commun., 2017,8, 452-464

2016: Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the inhibition of monoamine oxidases: Synthesis, in vitro biological evaluation and molecular modelling analysis. Abbas N, Zaib S, Bakht SM, Ibrar A, Khan I, Batool S, Saeed A, Iqbal J. Bioorg Chem. 2016 Nov 9. doi: 10.1016/j..

2016: Rapid Continuous Multimaterial Extrusion Bioprinting. Wanjun Liu, Yu Shrike Zhang, Marcel A. Heinrich, Fabio De Ferrari, Hae Lin Jang, Syeda Mahwish Bakht, Mario Mois´es Alvarez, Jingzhou Yang, Yi-Chen Li, Grissel Trujillo-de Santiago, Amir K. Miri, Kai Zhu, Parastoo Khoshakhlagh, Gyan Prakash,Hao Cheng, Xiaofei Guan, Zhe Zhong, Jie Ju, Geyunjian Zhu, Xiangyu Jin, Su Ryon Shin, Mehmet Remzi Dokmeci, and Ali Khademhosseini. Adv Mater. 2016 Nov 17. doi: 10.1002/

2016: Elastomeric Free-Form Blood Vessels for Interconnecting Organs on Chip Systems. Weijia Zhang, Yu Shrike Zhang, Syeda Mahwish Bakht, Julio Aleman, Su-Ryon Shin, Kan Yue, Marco Sica, João Ribas, Margaux Duchamp, Ramin Banan Sadeghian, Duckjin Kim, Mehmet Remzi Dokmeci Anthony Atala, and Ali Khademhosseini. Lab Chip. 2016 Apr 26;16(9):1579-86. doi: 10.1039/c6lc00001k.

2016:3D Bioprinting for Tissue and Organ Fabrication. Yu Shrike Zhang, Kan Yue, Julio Aleman, Kamyar Mollazadeh-Moghaddam, Syeda Mahwish Bakht, Jingzhou Yang, Weitao Jia, Valeria Dell'Erba, Pribpandao Assawes, Su Ryon Shin, Mehmet Remzi Dokmeci, Rahmi Oklu, Ali Khademhosseini Ann Biomed Eng 2016 Apr 28. Epub 2016 Apr 28.

2015: Synthesis, biological evaluation and molecular docking of N-phenyl thiosemicarbazones as urease inhibitors. Abdul Hameed, Khalid Mohammed Khan, Syeda Tazeen Zehra, Ramasa Ahmed, Zahid Shafiq, Syeda Mahwish Bakht, Muhammad Yaqub, Mazhar Hussain, Antonio de la Vega de León, Norbert Furtmann, Jürgen Bajorath, Hazoor Ahmad Shad, Muhammad Nawaz Tahir, Jamshed Iqbal. Bioorg. Chem Volume 61, 2015, 8 Pages 51–57.

2015: Exploration of a library of triazolothiadiazole and triazolothiadiazine compounds as a highly potent and selective family of cholinesterase and monoamine oxidase inhibitors: Design, synthesis, X-ray diffraction analysis and molecular docking studies. Imtiaz Khan,Syeda Mahwish Bakht, Aliya Ibrar,Saba Abbas,Shahid Hameed,Jonathan M. White,Usman Ali Rana,Sumera Zaib,Mohammad Shahid and Jamshed Iqbal. RSC Adv., 2015, 5, 21249-21267.

INDUSTRY EXPERIENCE

Amson vaccines & pharma pvt limited