KAUSHIK MISRA

Scopus Publications

Synthesis, Molecular Docking of Phenolic Amides and 2, 3 Diphenylacrylamide; Active Against Acid Fast Bacteria
Kaushik Misra, Ahindra Nag, Sharmi Ganguly, Himadri Sekhar Maity, Avinash Sonawane
Chemistryselect, 2025
A novel classes of hybrid molecules were synthesized where substituted phenolic acids and substituted 2, 3 diphenylacrylic acids (combretastatin analogue) were linked with phenastatin analogue through an amide linkage, respectively. In vitro study revealed that the novel amides (E)‐3‐(3,4‐dihydroxyphenyl)‐N‐(4‐(2,3,4‐ trimethoxybenzoyl) phenyl)acrylamide (9), 3,4,5‐trihydroxy‐N‐(4‐(2,3,4‐trimethoxybenzoyl) phenyl)benzamide (14), and (E)‐2,3‐bis(4‐hydroxyphenyl)‐N‐(4‐(2,3,4‐trimethoxybenzoyl)phenyl)acrylamide (20) were active against M. smegmatis with MIC value less than 50 µg mL−1, and a docking study showed those specific molecules were interacting with various amino acid residues of FabG4 of MTb. These novel amides might be useful for developing an alternative antibacterial agent which could control secondary infection, after a details SAR study.
Synthesis of β-Amino Alcohols from Value-Added Plant-Polyphenols Using ACC as a Green Reaction Medium and Mechanistic Study from DFT Analysis
Kaushik Misra, Bipasa Halder, Flora Banerjee, Gourhari Jana, Himadri Sekhar Maity, Aditya Balasaheb Kachave, Ahindra Nag
Polycyclic Aromatic Compounds, 2023
A simple, new, and cost-efficient alternative route has been designed for the synthesis of unique β-amino alcohols under metal-free condition from new type of 1,2- disubstituted styrene epoxides obtained from substituted p-hydroxycinnamic acids via greener approach. It was followed by density functional theory (DFT) based computational study to investigate the mechanistic path for generating acetylated amino alcohols i.e. the main key step for the formation of β-amino alcohols. Graphical Abstract
N -(2-Bromo-4-fluorophenyl)-3-(3,4-dihydroxyphenyl)-acrylamide (CPAM), a small catecholic amide as an antioxidant, anti diabetic and antibacterial compound
Kaushik Misra, Ahindra Nag, Avinash Sonawane
Rsc Advances, 2016
The trans conformation ofN-(2-bromo-4-fluorophenyl)-3-(3,4-dihydroxyphenyl)-acrylamide (CPAM), a small catecholic amide with halogen moieties, may be used as an anti diabetic compound.
CSJ acting as a versatile highly efficient greener resource for organic transformations
Himadri Sekhar Maity, Kaushik Misra, Tanushree Mahata, Ahindra Nag
Rsc Advances, 2016
We have reported the simple, new, greener biotransformation for the selective reduction of aromatic aldehydes, decarboxylation of aromatic acids and hydrolysis of aromatic compounds byCucumis sativusL. juice (CSJ).
Radical scavenging and antibacterial activity of caffemides against gram positive, gram negative and clinical drug resistance bacteria
Kaushik Misra, Himadri Sekhar Maity, Ahindra Nag, Avinash Sonawane
Bioorganic and Medicinal Chemistry Letters, 2016
New greener alternatives for bioreduction of aromatic aldehydes and decarboxylation of aromatic acids using juice of fruits
Kaushik Misra, Himadri Sekhar Maity, Subhankar Chanda, Ahindra Nag
Journal of Molecular Catalysis B Enzymatic, 2012
Valuable Vinylphenols from Rapeseed and Canola: Decarboxylative Pathways
Crystal L. Snyder, R. Weselake
Canola and Rapeseed Production Processing Food Quality and Nutrition, 2012

KAUSHIK MISRA

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Scopus Publications