Dr. Mohammad Chand Jamali is a senior clinical scientist and academician with over 25 years of professional experience in pathology and laboratory medicine. His career has been deeply rooted in diagnostic sciences, clinical biochemistry, and translational laboratory research, with sustained engagement in quality-assured and accredited laboratory environments.
He holds three PhDs in Biochemistry, Medicinal Chemistry, and Hospital Management. He also earned a Master’s degree in Criminology and Forensic Science with specialization in Forensic Toxicology and Forensic Pharmacology, reflecting his interdisciplinary expertise in analytical sciences, toxicological investigations, and evidence-based laboratory interpretation. In addition, he holds an MS and a Master of Public Health (MPH).
Dr. Jamali’s professional focus integrates clinical diagnostics, biomarker research, immune mediators, metabolic disorders, laboratory quality systems, and healthcare governance. As Asso
EDUCATION
Dr. Mohammad Chand Jamali is a senior academic and clinical scientist specializing in Pathology and laboratory medicine. He holds PhDs in Biochemistry, Medicinal Chemistry, and Hospital Management, and a Master’s degree in Criminology and Forensic Science (Forensic Toxicology and Forensic Pharmacology), along with an MS and MPH. He currently serves as Associate Professor at Liwa University, UAE.
RESEARCH, TEACHING, or OTHER INTERESTS
Multidisciplinary, Epidemiology, Health Informatics, Biochemistry, Genetics and Molecular Biology
Ethnomedicinal Uses, Phytochemical Constituents and Pharmacological Properties of Clerodendrum infortunatum Linn: A Review Rezwan Ahmed Mahedi, Sadia Afrin, Shokhida Rasulova Shukhrat Kizi, Mohammad Chand Jamali, Nikolaos Syrmos, et al. Natural Product Communications, 2026 Background Clerodendrum infortunatum L., a member of the Lamiaceae family, is an important ethnopharmacologically relevant plant that is widely used in the traditional management of infectious, inflammatory, metabolic, and parasitic diseases in South and Southeast Asia. Although this plant is widely used in traditional medicine, scientific evidence is still in an unorganized state. Objective The purpose of this review is to present consolidated information on ethnomedicinal uses, phytoconstituents, and pharmacological properties of Clerodendrum infortunatum. Methods Appropriate keywords were used in the search for relevant literature from Google Scholar and PubMed databases regarding the phytochemical, ethnomedicinal, and pharmacological effects of Clerodendrum infortunatum . Results Ethnomedical research shows that stems, roots, leaves, and flowers can be used as treatments for fever, helminthiasis, wound healing, inflammation, respiratory issues, skin problems, and envenomation. In secondary metabolite studies, research found elements such as flavonoids, phenolic acids, clerodane diterpenoids, phenolic acids, steroids, saponins, fatty acids, and nitrogen compounds. Preclinical research, mostly in vitro and in vivo studies, reports evidence of a wide range of biological activities such as inflammation, anti-infection, anti-helminth, liver protection, anti-diabetic, pain relief, anti-epileptic, wound healing, and anticancer activities. Conclusion The available evidence is mainly preclinical and has little to no mechanistic explanation, varies in extraction procedures, lacks standardization in plant matter, and has underdeveloped toxicity and pharmacokinetic studies. There are no clinical trials in humans, and some parts of plants, especially the fruits and flowers, are still understudied. Clerodendrum infortunatum is an ethnopharmacologically relevant species with some hopeful preclinical data, but the rigorous phytochemical standardisation, mechanistic study, thorough clinical trial design are critical to prove the potential of this plant in evidence-based therapeutics.
Clinical and Histopathological Evaluation of the Sinopharm COVID-19 Vaccine's Effects on Newborns and Placenta in Pregnant Women Sameh Fawzy Elsonbaty, Mohammad Chand Jamali, Maxime Merheb, Hend Mohamed Ahmed Hamed, Mohammed Abdalhamied M. Abushohada, et al. Research Journal of Pharmacy and Technology, 2026 The COVID-19 pandemic presents significant medical challenges, including unclear perinatal issues. Infection can occur at any stage of pregnancy, potentially leading to in utero transmission. Most studies indicate no significant clinical impact on fetal malformations or neonatal death from fetal infection. This study evaluates the importance of vaccinating pregnant women against COVID-19 and the potential for in utero transmission, correlating these factors with pathological findings in placental tissues and newborns. It examines how placental changes may contribute to neonatal symptoms and how vaccination reduces complications for both mothers and neonates. The study involves a retrospective clinicopathological analysis of 50 placental autopsies from non-vaccinated pregnant women aged 25-30 years infected with COVID-19 during the 2nd or 3rd trimester, compared to 50 autopsies from vaccinated women (with the Sinopharm vaccine) in the same age range and trimesters. Findings suggest that COVID-19 infection in non-vaccinated mothers leads to placental issues like placentitis and vessel obstruction, causing decreased perfusion, placental insufficiency, and perinatal problems such as fetal hypoxia. Vaccinated mothers showed minimal or no such complications. The study highlights the intimate relationship between neonatal complications and intrauterine COVID-19 infection, suggesting that including the COVID-19 vaccine in premarital vaccination programs could prevent these issues, benefiting both mothers and neonates.
Quantitative Analysis of Methanolic and Dichloromethane Extracts of Araucaria heterophylla: Formulation as Radical Scavenging Agents and Assessment of Flavonoid Content and Total Phenolic Ankita Ghosh, Mustafa Mudhafar, Raed Fanoukh Aboqader Al-Aouadi, Othman Mahjoob Khalaf, Md Abu Sayeed, et al. Research Journal of Pharmacy and Technology, 2026 Introduction: Araucaria heterophylla, commonly known as Norfolk Island Pine, is a plant with significant medicinal potential due to its rich phytochemical composition. This study aims to explore its antioxidant properties, given its widespread ornamental use and reported pharmacological activities. Secondary metabolites, a type of bioactive molecule with many functions, are abundant in Araucaria heterophylla. The secondary metabolites flavonoids, phenolic acid, and tannin have been found to have anti-inflammatory, antiviral, antibacterial, antioxidant, and anticancer properties. Objective: The objective of this study is to investigate the antioxidant activity of Araucaria heterophylla leaves through extraction and evaluation methods, shedding light on its medicinal relevance and it was also conducted to analyze the phytochemical and determine the total flavonoid, tannin, and phenolic content of Araucaria heterophylla leaves extract using two different solvents (methanol and dichloromethane) using UV-Vis spectrophotometric. Material and Methods: Araucaria heterophylla leaves were gathered, air-dried, and then extracted with methanol. To measure antioxidant activity, we used the DPPH free radical scavenging test, and to find the total antioxidant capacity, we used the phosphor molybdenum technique. To determine the total content of tannin, phenolic, and flavonoid in Araucaria heterophylla, the methanolic extract was made after the plant was recognized by NHB (ID No: DACB 48435). The total phenolic and tannin content was investigated using the Folin-Ciocaltu technique. Result: The methanolic and dichloromethane extracts exhibited significant antioxidant activity, with IC50 values of 45.98 μg/mL and 58.70 μg/mL, respectively. These results suggest the presence of potent antioxidant compounds in Araucaria heterophylla, highlighting its therapeutic potential. The A. heterophylla leaf methanolic and dichloromethane extracts had remarkable antioxidant effects due to their high flavonoid and phenolic content. Conclusion: Araucaria heterophylla leaves demonstrate promising antioxidant properties attributed to their flavonoid and phenolic content. Further research focusing on standardization, stability, and clinical trials could lead to the development of novel therapeutic agents from this plant.
Sirtuin1: A Potential Key Regulator in Alzheimer's Disease Pathophysiology and Therapeutics Preeti Chandola, Smita Jain, Pragya Sharma, Mohammad Chand Jamali, Jaya Dwivedi, et al. Current Enzyme Inhibition, 2025 Sirtuin 1 (SIRT1), an NAD+-dependent deacetylase, plays a vital role in neurodegenerative diseases, particularly Alzheimer’s disease (AD). SIRT1 exerts neuroprotective effects by modulating oxidative stress, neuroinflammation, and mitochondrial function while promoting neuronal survival. It enhances amyloid-β (Aβ) clearance by activating α-secretase and inhibiting β-secretase, thereby reducing Aβ aggregation. Beyond protein aggregation, SIRT1 also influences mitochondrial biogenesis and function via peroxisome proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1α), thereby enhancing energy metabolism and reducing oxidative damage. Moreover, SIRT1-mediated deacetylation of nuclear factor kappa B (NF-κB) suppresses neuroinflammation, further contributing to neuroprotection. Preclinical studies highlight the therapeutic potential of SIRT1 activators, such as resveratrol, in improving cognitive function and reducing AD pathology. However, challenges such as bioavailability, pharmacokinetics, and the lack of definitive clinical validation hinder its therapeutic translation. Emerging research suggests that lifestyle factors, including caloric restriction, exercise, and sleep modulation, may naturally enhance SIRT1 activity, offering alternative approaches for AD prevention. Despite promising evidence, further research is required to fully elucidate the mechanisms underlying SIRT1’s role in AD and to develop effective, targeted therapies. This review underscores SIRT1’s multifaceted involvement in AD pathophysiology and its potential as a therapeutic target, calling for multidisciplinary efforts to advance its clinical application.
Exploring creative linkages of healthcare industry and academia in United Arab Emirates (1970 – 2018) International Journal of Scientific and Technology Research, 2020
Involvement of the PD-1 pathway in the modulation of immune responses during allergic diseases AH Mohamed, RI Al-Samawi, MC Jamali, S Abdul-Jabbar Ali, AA Patel, ... Inflammation Research 75 (1), 75 , 2026 2026
Ethnomedicinal Uses, Phytochemical Constituents and Pharmacological Properties of Clerodendrum infortunatum Linn: A Review RA Mahedi, S Afrin, SR Shukhrat Kizi, MC Jamali, N Syrmos, G Bexruz, ... Natural Product Communications 21 (4), 1934578X261440432 , 2026 2026
Blockchain and Cryptocurrency: Regulatory Challenges & Opportunities P Priyadarshi, S Kumar, AN Sinha, N Singh, M Jamali Regulation and Inclusivity in Finance and Accounting: Navigating Regulatory … , 2026 2026
Quantitative Analysis of Methanolic and Dichloromethane Extracts of Araucaria heterophylla: Formulation as Radical Scavenging Agents and Assessment of Flavonoid Content and … A Ghosh, M Mudhafar, RFA Al-Aouadi, OM Khalaf, MA Sayeed, M Imran, ... Research Journal of Pharmacy and Technology 19 (2), 795-803 , 2026 2026
Engineering scFv immunotherapies: From CAR T cells to bispecific antibodies MC Jamali, AGM Gaffer, HG Hassan, SAJ Ali, MK Sulaiman, A Tariq, ... International Immunopharmacology 166, 115597 , 2025 2025 Citations: 2
The immunobiological functions and therapeutic applications of interleukin-17 family in cancer N Mansuri, HM Asma'a, M Ahsan, SAJ Ali, MA Qureshi, WA Aldhaaban, ... Current Research in Translational Medicine 73 (4), 103527 , 2025 2025 Citations: 1
Bortezomib in multiple myeloma management H Iqbal, MN Islam, S Chakravarthi, MC Jamali, RA Mahedi, S Afrin, P Roy, ... Universa Medicina 44 (3), 380-393 , 2025 2025
Ethnomedicinal Significance, Phytochemical Profile, and Therapeutic Potentials of Artocarpus chama (Chapalish): A Review S Afrin, T Sultana, MM Rana, MM Rahman, A Hasan, AMW Hasan, ... Research Journal of Pharmacy and Technology 18 (10), 5109-5118 , 2025 2025 Citations: 1
Receptor-based pharmacophore modelling for the discovery of Sirtuin 1 modulators in Alzheimer’s disease P Chandola, S Jain, R Singh, MC Jamali, J Dwivedi, S Sharma, KM Keli, ... Analytical Chemistry Letters 15 (4), 637-652 , 2025 2025
Foundations of Medical Physiology and Clinical Pharmacology: An Integrated Foundation of Physiological Concepts and Clinical Pharmacology for Medical Education and Practice| Dr … MC Jamali, R Singh, P Singh, MP Swain Academic Guru Publishing House , 2025 2025
The role of probiotics in promoting systemic immune tolerance in systemic lupus erythematosus AH Mohamed, A Shafie, RI Al-Samawi, MC Jamali, AA Ashour, ... Gut Pathogens 17 (1), 45 , 2025 2025 Citations: 10
Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease MC Jamali, AH Mohamed, A Jamal, MA Kamal, W Al Abdulmonem, ... Journal of Inflammation 22 (1), 17 , 2025 2025 Citations: 7
A Narrative Review on Morphological Description, Ethnomedicinal Usage, Phytochemical Constituents and Pharmacological Activities: Microcos paniculata S Afrin, MS Islam, SB Kondaveeti, HS Batra, R Azmee, M Azmee, F Jakir, ... Research Journal of Pharmacy and Technology 18 (3), 1419-1427 , 2025 2025 Citations: 1
Human Anatomy and Medical Physiology: An Integrated Approach MC Jamali Academic Guru Publishing House , 2025 2025
Sirtuin1: A Potential Key Regulator in Alzheimer's Disease Pathophysiology and Therapeutics P Chandola, S Jain, P Sharma, MC Jamali, J Dwivedi, S Sharma Current Enzyme Inhibition , 2025 2025 Citations: 1
Computational and Systematic Analysis of Zosurabalpin (RG6006) against Cancerous and Pathogenic Microbial Proteins S Afrin, RA Mahedi, MJ Kadham, MC Jamali, S Das, H Iqbal, ... Research Journal of Pharmacy and Technology 18 (8), 3541-3548 , 2025 2025
Gene characterization and computational identification of potential phytochemicals against non-small cell lung carcinoma S Srivastava, A Bagri, VJ Upadhye, AG Mostafa, MC Jamali, SP Kollur, ... Plant Science Today 12 (3) , 2025 2025
Chapter-2 Viral Mechanisms and Pathogenesis MC Jamali, S Afrin, MA Sayeed, S Paul, AMW Hasan, LC De Guia, ... Emerging Trends in Medical Sciences, 9 , 2025 2025
Exposures to poisoning to forensic investigations and public health views-A toxicology tapestry P Viktor, L Kaur, HPJS Pillai, OM Khalaf, M Mudhafar, H Hasan, J Devi, ... Research Journal of Pharmacy and Technology 18 (1), 402-408 , 2025 2025 Citations: 3
Diabetic kidney disease: an overview of prevalence, risk factors, and biomarkers. Clin Epidemiol Glob Health. 2021; 9: 2–6 S Hussain, MC Jamali, A Habib, MS Hussain, M Akhtar, AK Najmi 2025 Citations: 12
MOST CITED SCHOLAR PUBLICATIONS
Diabetic kidney disease: An overview of prevalence, risk factors, and biomarkers S Hussain, MC Jamali, A Habib, MS Hussain, M Akhtar, AK Najmi Clinical Epidemiology and Global Health 9, 2-6 , 2021 2021 Citations: 222
Burden of diabetes mellitus and its impact on COVID-19 patients: a meta-analysis of real-world evidence S Hussain, H Baxi, MC Jamali, N Nisar, MS Hussain Diabetes & Metabolic Syndrome: Clinical Research & Reviews 14 (6), 1595-1602 , 2020 2020 Citations: 75
Interleukin-6 serves as a critical factor in various cancer progression and therapy AH Mohamed, AT Ahmed, W Al Abdulmonem, DO Bokov, A Shafie, ... Medical Oncology 41 (7), 182 , 2024 2024 Citations: 64
No association between proton pump inhibitor use and risk of dementia: Evidence from a meta‐analysis S Hussain, A Singh, S Zameer, MC Jamali, H Baxi, SO Rahman, M Alam, ... Journal of gastroenterology and hepatology 35 (1), 19-28 , 2020 2020 Citations: 54
Effects of long-term dehydration on stress markers, blood parameters, and tissue morphology in the dromedary camel ( Camelus dromedarius ) MA Ali, H Abu Damir, MA Adem, OM Ali, N Amir, AAM Shah, ... Frontiers in Veterinary Science 10, 1236425 , 2023 2023 Citations: 22
Impact of bariatric surgery in reducing macrovascular complications in severely obese T2DM patients S Hussain, MS Khan, MC Jamali, AN Siddiqui, G Gupta, MS Hussain, ... Obesity Surgery 31 (5), 1929-1936 , 2021 2021 Citations: 17
Non-linear optical activity and biological evaluation of organic compounds by experimental and theoretical techniques P Chandola, J Dwivedi, MC Jamali Eur. Chem. Bull. 12 (4), 19608-19619 , 2023 2023 Citations: 16
Diabetic kidney disease: an overview of prevalence, risk factors, and biomarkers. Clin Epidemiol Glob Health. 2021; 9: 2–6 S Hussain, MC Jamali, A Habib, MS Hussain, M Akhtar, AK Najmi 2025 Citations: 12
ANTIMICROBIAL ACTIVITY OF PHYLLANTHUS EMBLICA MC Jamali Journal of Bioinnovation 5 (vi), 979-984 , 2016 2016 Citations: 11
The role of probiotics in promoting systemic immune tolerance in systemic lupus erythematosus AH Mohamed, A Shafie, RI Al-Samawi, MC Jamali, AA Ashour, ... Gut Pathogens 17 (1), 45 , 2025 2025 Citations: 10
Lean and Six Sigma in healthcare: Examining the impact on patient safety and quality of care A Jain, R Sharma, MC Jamali Seybold Rep 18, 2680-95 , 2023 2023 Citations: 8
Biological mechanisms and therapeutic prospects of interleukin-33 in pathogenesis and treatment of allergic disease MC Jamali, AH Mohamed, A Jamal, MA Kamal, W Al Abdulmonem, ... Journal of Inflammation 22 (1), 17 , 2025 2025 Citations: 7
Eltrombopag Olamine in Dengue Fever:Systematic Review of Clinical Trials and Beyond FR Sadia Afrin,Md. Shanzid Hasan,Md. Rezwan Ahmed Mahedi,Ovijet Chandra Kuri ... Research Journal of Pharmacy and Technology 17 (6), 2778-2782 , 2024 2024 Citations: 7
The Importance of Bioinformatics in the field of Biomedical Science S Shahi, SK Singh, MC Jamali International Journal of Bioinformatics 1 (1), 1-5 , 2022 2022 Citations: 7
Amputation risk in type II diabetes mellitus patients treated with SGLT-2 inhibitors: a systematic literature review of randomized clinical trials F Hoda, MC Jamali, M Arshad, MA Habib, M Akhtar, AK Najmi Drug Research 74 (09), 425-432 , 2024 2024 Citations: 6
Exploring The Massive Amounts of Biological Data and Its Role in Treating Patients S Shahi, SK Singh, MC Jamali International Journal of Medical Sciences 2 (1), 2815-0562 , 2022 2022 Citations: 6
Assessment of Biochemical Markers for Early Detection and Monitoring of Cardiovascular Diseases: Myocardial Infarction and Heart Failure SM Nair, A Pareek, MC Jamali Quality Assurance 15 (1), 288-95 , 2024 2024 Citations: 5
Current Thoughts on Dementia GM Ashraf, MS Uddin 2022 Citations: 5
Synthesis, Characterization and Targeted Drug Delivery of Curcumin-Loaded PLGA Nanoparticles MC Jamali, AGM Gaffer, E Sameh, J Yasin Journal of Angiotherapy 8 (10), 1-6 , 2024 2024 Citations: 4
Emerging Biomarkers for Early Detection of Cardiovascular Disease MJ Kutagolla Peera, Anurag Rawat, Sarath M. Nair, Obaiah Jamakal Journal of Advance Zoology 44 (S3), 1672-1683 , 2023 2023 Citations: 4