Vinícius Augusto Simão

@usp.br

University of Sao Paulo



                    

https://researchid.co/mormvin
12

Scopus Publications

158

Scholar Citations

7

Scholar h-index

6

Scholar i10-index

Scopus Publications

  • Adipose-derived stem cells (ASCs) culture in spinner flask: improving the parameters of culture in a microcarrier-based system
    Vinícius Augusto Simão, Heloisa Brand, Roseli Nunes da Silveira-Antunes, Josianne Thomazini Fukasawa, Jaci Leme, Aldo Tonso, and João Tadeu Ribeiro-Paes

    Springer Science and Business Media LLC

  • Epigenetic Mechanisms Involved in Inflammaging-Associated Hypertension
    Vinícius Augusto Simão, León Ferder, Walter Manucha, and Luiz Gustavo A. Chuffa

    Springer Science and Business Media LLC

  • Melatonin Regulates the Daily Levels of Plasma Amino Acids, Acylcarnitines, Biogenic Amines, Sphingomyelins, and Hexoses in a Xenograft Model of Triple Negative Breast Cancer
    Rubens Paula Junior, Luiz Gustavo de Almeida Chuffa, Vinicius Augusto Simão, Nathália Martins Sonehara, Roger Chammas, Russel J. Reiter, and Debora Aparecida Pires de Campos Zuccari

    International journal of molecular sciences MDPI AG
    Metabolic dysregulation as a reflection of specific metabolite production and its utilization is a common feature of many human neoplasms. Melatonin, an indoleamine that is highly available during darkness, has a variety of metabolic functions in solid tumors. Because plasma metabolites undergo circadian changes, we investigated the role of melatonin on the profile of amino acids (AAs), biogenic amines, carnitines, sphingolipids, and hexoses present in the plasma of mice bearing xenograft triple negative breast cancer (MDA-MB-231 cells) over 24 h. Plasma concentrations of nine AAs were reduced by melatonin, especially during the light phase, with a profile closer to that of non-breast cancer (BC) animals. With respect to acylcarnitine levels, melatonin reduced 12 out of 24 molecules in BC-bearing animals compared to their controls, especially at 06:00 h and 15:00 h. Importantly, melatonin reduced the concentrations of asymmetric dimethylarginine, carnosine, histamine, kynurenine, methionine sulfoxide, putrescine, spermidine, spermine, and symmetric dimethylarginine, which are associated with the BC metabolite sets. Melatonin also led to reduced levels of sphingomyelins and hexoses, which showed distinct daily variations over 24 h. These results highlight the role of melatonin in controlling the levels of plasma metabolites in human BC xenografts, which may impact cancer bioenergetics, in addition to emphasizing the need for a more accurate examination of its metabolomic changes at different time points.

  • Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved
    Virna Margarita Martín Giménez, Luiz Gustavo A. Chuffa, Vinícius Augusto Simão, Russel J. Reiter, and Walter Manucha

    Elsevier BV

  • Melatonin-loaded nanocarriers: New horizons for therapeutic applications
    Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Adriana Alonso Novais, Vinícius Augusto Simão, Virna Margarita Martín Giménez, Walter Manucha, Debora Aparecida Pires de Campos Zuccari, and Russel J. Reiter

    MDPI AG
    The use of nanosized particles has emerged to facilitate selective applications in medicine. Drug-delivery systems represent novel opportunities to provide stricter, focused, and fine-tuned therapy, enhancing the therapeutic efficacy of chemical agents at the molecular level while reducing their toxic effects. Melatonin (N-acetyl-5-methoxytriptamine) is a small indoleamine secreted essentially by the pineal gland during darkness, but also produced by most cells in a non-circadian manner from which it is not released into the blood. Although the therapeutic promise of melatonin is indisputable, aspects regarding optimal dosage, biotransformation and metabolism, route and time of administration, and targeted therapy remain to be examined for proper treatment results. Recently, prolonged release of melatonin has shown greater efficacy and safety when combined with a nanostructured formulation. This review summarizes the role of melatonin incorporated into different nanocarriers (e.g., lipid-based vesicles, polymeric vesicles, non-ionic surfactant-based vesicles, charge carriers in graphene, electro spun nanofibers, silica-based carriers, metallic and non-metallic nanocomposites) as drug delivery system platforms or multilevel determinations in various in vivo and in vitro experimental conditions. Melatonin incorporated into nanosized materials exhibits superior effectiveness in multiple diseases and pathological processes than does free melatonin; thus, such information has functional significance for clinical intervention.

  • Nandrolone decanoate causes uterine injury by changing hormone levels and sex steroid receptors in a dose- and time-dependent manner
    Vinícius Augusto Simão, Luiz Antonio Lupi Júnior, Gabriel Adan Araujo Leite, Isabel Cristina Cherici Camargo, and Luiz Gustavo de Almeida Chuffa

    Elsevier BV
    Different doses of nandrolone decanoate (ND) were used to investigate the expression of uterine sex steroid receptors (AR, ER-α, and ER-β) and the levels of serum sex hormones after treatment and recovery periods in adult rats. ND doses of 1.87, 3.75, 7.5, or 15 mg/kg b.w. or mineral oil (control group) were injected subcutaneously for 15 days, and the experimental groups were divided into three periods of evaluation: (a) ND treatment for 15 days, (b) ND treatment followed by 30-day-recovery and (c) ND treatment followed by 60-day-recovery. Estrous cycle was monitored daily. At the end of each experimental period, rats were euthanized for the collection of serum samples and uterine tissues. All animals showed persistent diestrus and only the highest ND dose was capable of inducing persistent diestrus until 60-day-recovery. Immunoexpression of uterine sex steroid receptors varied in a time-dependent manner. While AR expression was increase after treatment period, ER-α and ER-β expressions decreased after 60- and 30-day-recovery, respectively. ND also increased the serum levels of testosterone, 17β-estradiol, and dihydrotestosterone, especially at the highest doses of 7.5 and 15 mg ND/kg until 30 days of recovery. The levels of progesterone were significantly reduced in all ND-treated animals. No significant difference was observed in the levels of follicle-stimulating hormone, whereas the levels of luteinizing hormone varied according to specific dose and period. We conclude that uterine sex steroid receptors and sex hormones are affected by ND administration and these alterations can be only restored following lower doses and long recovery periods.

  • Metabolic and proliferation evaluation of human adipose-derived mesenchymal stromal cells (ASC) in different culture medium volumes: standardization of static culture
    Vinícius Augusto Simão, Caetano Pedro Evangelista-Ribeiro, Heloisa Brand, Lougan Lagass-Pereira, Laís Fernanda Marques, Pedro Henrique Benites-Aoki, Roseli Nunes da Silveira-Antunes, Aldo Tonso, and João Tadeu Ribeiro-Paes

    Elsevier BV
    Adipose-derived mesenchymal stromal/stem cells (ASC) have acquired a prominent role in tissue engineering and regenerative medicine. However, the standardization of basic culture procedures in this cellular type is still not well established according to the main qualitative cellular attributes. We evaluate the cell growth profile of human ASC in a different culture medium volumes and their nutritional composition utilizing static cultivation. Culture medium volumes (5, 10 and 15 mL/25 cm2) in T-flasks were evaluated by kinetic parameters and the metabolic composition was determined by biochemical analysis and Fourier transform infrared (FT-IR) absorption spectroscopy. 50% renewal of culture medium volume every 48 h was adopted. Immunophenotypic characterization and cell differentiation were performed. There was no difference (p > 0.05) in the kinetic parameters of cell proliferation between the culture medium volumes or in FT-IR composition. However, the concentrations of glucose, glutamine, lactate, and glutamate varied significantly during the cultivation process as a function of the medium volume. ASC presented specific antigens and differentiation potential of mesenchymal stromal/stem cells. It was concluded that the minimal culture medium volume (5 mL/25 cm2 in static culture) was sufficient to maintain the stability, potency, and growth of ASC, representing an economic and safe standardization for this cell culture process.

  • Histopathological changes in androgenized ovaries are recovered by melatonin treatment
    Bianca R. de Souza, Luiz Gustavo de Almeida Chuffa, Vinícius Augusto Simão, and Isabel C. C. Camargo

    Wiley
    Nandrolone decanoate (ND) is a synthetic steroid, which promotes adverse effects on the ovarian tissue, and melatonin (MLT) exhibits a number of beneficial properties in the reproductive system. This study evaluated the general features of the ovarian tissue and the immunoexpression of sex steroid receptors in ND‐treated rats that were submitted to short‐term melatonin treatment. Adult rats received mineral oil (control group) and ND at doses of 7.5 mg/kg for 15 days (ND‐treated group). The treatment with MLT (10mg/kg for 7 days) was given alone, before or in combination with ND. All ND‐treated animals showed persistent dioestrus. In the androgenized groups that received MLT, ovarian morphology and size, and the number/area of corpora lutea were recovered. The number of healthy and atretic follicles was recovered when MLT was administered prior to ND; this was similar to the ovaries of control and MLT groups. There was a decrease in estrogen receptors immunostaining in the follicles of androgenized rats that were treated with MLT, and pretreatment with MLT reduced the expression of androgen receptor in atretic follicles and corpora lutea, when compared with ND‐treated group. We conclude that MLT treatment recovered the histopathological aspects of the androgenized ovaries, and MLT pretreatment was the most effective.

  • Sex steroid receptors profiling is influenced by nandrolone decanoate in the ampulla of the fallopian tube: Post-treatment and post-recovery analyses
    G.H.B. Andrade, V.A. Simão, B.R. Souza, L.G.A. Chuffa, and I.C.C. Camargo

    Elsevier BV
    Anabolic androgenic steroids (AAS) are recommended for therapeutic clinic, but their use has increased in recent decades for aesthetic reasons. No study has evaluated the impact of AAS in the fallopian tube, after treatment and recovery periods. Herein, the aim of study was to investigate the effects of Nandrolone Decanoate (ND), administered in different doses (1.87; 3.75; 7.5 and 15 mg/kg) on the ampulla of the fallopian tube in rats, following post-treatment (PT; 15 consecutive days) and post-recovery (PR; 30 consecutive days) periods. The control group received mineral oil. Estrous cycle was monitored daily during both periods and in sequence the rats (n = 8/group/period) were killed. All ND-treated animals showed estral acyclicity during the PT and PR periods, but the histomorphometric changes in the fallopian tube varied according to the ND dose level. The expression of AR, ERα and ERβ varied in the nucleus and cytoplasm of epithelial cells. No AR expression was observed in the stroma. The muscle cells exhibited variation in immunostaining. In conclusion, ND promoted histomorphometric and immunohistochemical changes in the ampullary portion of the fallopian tube after treatment and recovery periods in a dose-independent manner.

  • Ovarian sex steroid receptors and sex hormones in androgenized rats
    Vinícius Augusto Simão, Luiz Gustavo de Almeida Chuffa, and Isabel Cristina Cherici Camargo

    Bioscientifica
    This study evaluated for the first time the effects of different doses of the anabolic steroid nandrolone decanoate (ND) on the expression of ovarian steroid receptors (AR, ER-α (ESR1) and ER-β (ESR2)) and related sex hormones after treatment and recovery periods in adult rats. The animals were injected subcutaneously with doses of ND (1.87, 3.75, 7.5 or 15 mg/kg b.w.) or mineral oil (control group) for 15 days, and the experimental groups were divided into three periods of evaluation: (a) ND treatment for 15 days, (b) ND treatment and recovery for a period of 30 days and (c) ND treatment and recovery for a period of 60 days. Estrous cycle was monitored daily. At the end of each period, rats were killed for collection of blood and ovaries. Persistent diestrus occurred in all rats during ND treatment and after 30-day recovery. The highest dose of ND was able to maintain all rats arrested at diestrus until 60-day recovery. The expression of steroid receptors varied in a dose- and period-dependent manner, having a more pronounced response with the dose of 15 mg ND/kg. ND treatment increased serum levels of testosterone, 17β-estradiol and dihydrotestosterone, especially at the highest doses of 7.5 and 15 mg ND/kg. No change was observed in the levels of follicle-stimulating hormone (FSH), whereas levels of the luteinizing hormone (LH) varied according to the dose and period. In conclusion, the ovarian sex steroid receptors and sex hormones were restored only at lower doses of ND and after a longer period of recovery.

  • Effects of different doses of nandrolone decanoate on estrous cycle and ovarian tissue of rats after treatment and recovery periods
    Vinícius Augusto Simão, Larissa Berloffa Belardin, Gabriel Adan Araújo Leite, Luiz Gustavo de Almeida Chuffa, and Isabel Cristina Cherici Camargo

    Wiley
    This study tested the hypothesis that different doses of nandrolone decanoate (ND) will cause changes in the estrous cycle and ovarian tissue of adult rats; and investigated the duration of the recovery period that is sufficient to restore the damage in the animals treated with different doses. Wistar rats were treated with ND at doses of 1.87, 3.75, 7.5 and 15 mg/kg body weight, or received mineral oil (control group) for 15 days, subcutaneously. All animals were divided into three groups according to the treatment periods: (i) ND treatment for 15 days; (ii) ND treatment followed by a 30‐day recovery; and (iii) ND treatment followed by a 60‐day recovery. Estrous cycle was monitored daily, and at the end of each period, the animals were euthanized for histopathological analysis. During ND treatment and after 30‐day recovery, all animals exhibited persistent diestrus. After a 60‐day recovery, persistent diestrus was only maintained in the group that had received the highest dose. Ovarian weight was decreased significantly after the 30‐day recovery, regardless of ND doses, compared with the control group. There was a reduction (P < 0.05) in the number of corpora lutea and antral and growing follicles, in contrast to an increase (P < 0.05) in atretic follicles in a dose‐ and time‐dependent manner. Remarkable histopathological changes occurred in the ovaries of all ND‐treated groups. In conclusion, the different doses of ND caused changes in the estrous cycle and ovarian tissue of rats, and recovery periods (30 and 60 days) were insufficient to completely restore the damage in the animals treated with the highest dose.

  • Dose-dependent effects and reversibility of the injuries caused by nandrolone decanoate in uterine tissue and fertility of rats
    Larissa Berloffa Belardin, Vinícius Augusto Simão, Gabriel Adan Araújo Leite, Luiz Gustavo de Almeida Chuffa, and Isabel Cristina Cherici Camargo

    Wiley
    This study is the first to investigate the effects of different doses of nandrolone decanoate (ND) upon uterine tissue and fertility, and if the reproductive alterations can be restored after cessation of the treatment. Wistar female rats were treated with ND at doses of 1.87, 3.75, 7.5, and 15 mg/kg body weight, diluted in vehicle (n = 30/group), or received only mineral oil (control group, n = 45). The animals were divided into three periods of study: ND-treated receiving a daily subcutaneous injection for 15 consecutive days (1), and treatment with ND followed by 30-day recovery (2), and 60-day recovery (3). At the end of each period, five females per group were induced to death to histopathological analysis and the others were allowed to fertility evaluation (at 19th gestational day). Animals that received ND followed by 30-day recovery exhibited persistent diestrous and marked suppression of reproductive capacity. Conversely, after 60-day recovery, only lowest doses females (1.87 and 3.75 mg/kg) exhibited restoration of normal estrous cyclicity. Uterine weights were increased after ND treatment similarly to that of the controls after 60-day recovery. The ND-treated groups showed histopathological changes in the endometrium, myometrium, and perimetrium, and an increase in the thickness of both muscular and serous layers. Notably, the recovery of uterine tissue after ND treatment was dose- and period-dependent. We reported that administration of ND promoted damage in uterine tissue and fertility of rats, and the recovery periods were insufficient to restore all of the side effects caused by ND under a dose-dependent response.

RECENT SCHOLAR PUBLICATIONS

  • Adipose-derived stem cells (ASCs) culture in spinner flask: improving the parameters of culture in a microcarrier-based system
    VA Simo, H Brand, RN da Silveira-Antunes, JT Fukasawa, J Leme, ...
    Biotechnology Letters 45 (7), 823-846 2023

  • Epigenetic mechanisms involved in inflammaging-associated hypertension
    VA Simo, L Ferder, W Manucha, LGA Chuffa
    Current Hypertension Reports 24 (11), 547-562 2022

  • Melatonin regulates the daily levels of plasma amino acids, acylcarnitines, biogenic amines, sphingomyelins, and hexoses in a xenograft model of triple negative breast cancer
    RP Junior, LGA Chuffa, VA Simo, NM Sonehara, R Chammas, RJ Reiter, ...
    International journal of molecular sciences 23 (16), 9105 2022

  • Zuccari, DAPDC Melatonin Regulates the Daily Levels of Plasma Amino Acids, Acylcarnitines
    RP Junior, L Chuffa, VA Simo, NM Sonehara, R Chammas, RJ Reiter
    Biogenic Amines, Sphingomyelins, and Hexoses in a Xenograft Model of Triple 2022

  • Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved
    VMM Gimnez, LGA Chuffa, VA Simo, RJ Reiter, W Manucha
    Life Sciences 288, 120191 2022

  • Melatonin-loaded nanocarriers: New horizons for therapeutic applications
    LGA Chuffa, FRF Seiva, AA Novais, VA Simo, VM Martn Gimnez, ...
    Molecules 26 (12), 3562 2021

  • Nandrolone decanoate causes uterine injury by changing hormone levels and sex steroid receptors in a dose-and time-dependent manner
    VA Simao, LAL Jnior, GAA Leite, ICC Camargo, LG de Almeida Chuffa
    Reproductive Toxicology 102, 98-108 2021

  • ESTABELECIMENTO DE UM BIOPROCESSO PARA PROLIFERAO EM LARGA ESCALA DE CLULAS ESTROMAIS MESENQUIMAIS DERIVADAS DE TECIDO ADIPOSO HUMANO
    VA Simo, JAR Fracasso, MJ Malagutti-Ferreira, A Tonso, ...
    Hematology, Transfusion and Cell Therapy 42, 418-419 2020

  • Estabelecimento de um bioprocesso para proliferao de clulas estromais mesenquimais derivadas de tecido adiposo humano em biorreator
    VA Simo
    Universidade de So Paulo 2020

  • Metabolic and proliferation evaluation of human adipose-derived mesenchymal stromal cells (ASC) in different culture medium volumes: standardization of static culture
    VA Simo, CP Evangelista-Ribeiro, H Brand, L Lagass-Pereira, ...
    Biologicals 62, 93-101 2019

  • Histopathological changes in androgenized ovaries are recovered by melatonin treatment
    BR de Souza, LG de Almeida Chuffa, VA Simo, ICC Camargo
    International journal of experimental pathology 99 (4), 158-171 2018

  • Sex steroid receptors profiling is influenced by nandrolone decanoate in the ampulla of the fallopian tube: Post-treatment and post-recovery analyses
    GHB Andrade, VA Simo, BR Souza, LGA Chuffa, ICC Camargo
    Tissue and Cell 50, 79-88 2018

  • Proliferao de clulas-tronco derivadas de tecido adiposo humano: influncia do volume de meio de cultura sobre a cintica de crescimento e parmetros de identidade celular (2017)
    CPE Ribeiro, VA Simo, H Brand, LL Pereira, MSF Tsuboy, PHB Aoki, ...
    Resumos 2017

  • Assessment of estrous cycle, ovarian and uterine tissue and fetal parameters of Wistar rats treated with Topiramate
    ICC Camargo, WE Neres, APQ Mello, VA Simo
    2017

  • Ovarian sex steroid receptors and sex hormones in androgenized rats
    VA Simo, LG de Almeida Chuffa, IC Cherici Camargo
    Reproduction 152 (5), 545-59 2016

  • CB. Avaliao do tratamento com melatonina na supresso dos efeitos colaterais promovidos pelo decanoato de nandrolona no ciclo estral e no tecido uterino de ratas
    HO Silva, BR Santos, VA Simo, LGA Chuffa, ICC Camargo
    Journal of Basic and Applied Pharmaceutical Sciencies 37 (1) 2016

  • Anlise hormonal, imunolocalizao e quantificao dos receptores de andrgenos (AR) e estrgenos (ER-α E ER-β) em ovrio e tero de ratas submetidas a diferentes doses de
    VA Simo
    Universidade Estadual Paulista (Unesp) 2016

  • Avaliao do ciclo estral, tecido ovariano e uterino e parmetros fetais de ratas Wistar tratadas com Topiramato
    ICC Camargo, WE Neres, APQ Mello, VA Simo
    Semina: Cincias Biolgicas e da Sade 37 (2), 55-70 2016

  • Effects of different doses of nandrolone decanoate on estrous cycle and ovarian tissue of rats after treatment and recovery periods
    VA Simo, L Berloffa Belardin, GA Araujo Leite, LG de Almeida Chuffa, ...
    International Journal of Experimental Pathology 96 (5), 338-349 2015

  • A busca pelo corpo perfeito vale a pena?: uma abordagem geral
    AEMC Silva, BR Souza, VA Simo, ICC Camargo
    Universidade Estadual Paulista (Unesp) 2015

MOST CITED SCHOLAR PUBLICATIONS

  • Dose‐dependent effects and reversibility of the injuries caused by nandrolone decanoate in uterine tissue and fertility of rats
    LB Belardin, VA Simo, GAA Leite, LGA Chuffa, ICC Camargo
    Birth Defects Research Part B: Developmental and Reproductive Toxicology 101 2014
    Citations: 29

  • Melatonin-loaded nanocarriers: New horizons for therapeutic applications
    LGA Chuffa, FRF Seiva, AA Novais, VA Simo, VM Martn Gimnez, ...
    Molecules 26 (12), 3562 2021
    Citations: 26

  • Effects of different doses of nandrolone decanoate on estrous cycle and ovarian tissue of rats after treatment and recovery periods
    VA Simo, L Berloffa Belardin, GA Araujo Leite, LG de Almeida Chuffa, ...
    International Journal of Experimental Pathology 96 (5), 338-349 2015
    Citations: 25

  • Ovarian sex steroid receptors and sex hormones in androgenized rats
    VA Simo, LG de Almeida Chuffa, IC Cherici Camargo
    Reproduction 152 (5), 545-59 2016
    Citations: 14

  • Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved
    VMM Gimnez, LGA Chuffa, VA Simo, RJ Reiter, W Manucha
    Life Sciences 288, 120191 2022
    Citations: 12

  • Sex steroid receptors profiling is influenced by nandrolone decanoate in the ampulla of the fallopian tube: Post-treatment and post-recovery analyses
    GHB Andrade, VA Simo, BR Souza, LGA Chuffa, ICC Camargo
    Tissue and Cell 50, 79-88 2018
    Citations: 11

  • Histopathological changes in androgenized ovaries are recovered by melatonin treatment
    BR de Souza, LG de Almeida Chuffa, VA Simo, ICC Camargo
    International journal of experimental pathology 99 (4), 158-171 2018
    Citations: 8

  • Epigenetic mechanisms involved in inflammaging-associated hypertension
    VA Simo, L Ferder, W Manucha, LGA Chuffa
    Current Hypertension Reports 24 (11), 547-562 2022
    Citations: 7

  • Melatonin regulates the daily levels of plasma amino acids, acylcarnitines, biogenic amines, sphingomyelins, and hexoses in a xenograft model of triple negative breast cancer
    RP Junior, LGA Chuffa, VA Simo, NM Sonehara, R Chammas, RJ Reiter, ...
    International journal of molecular sciences 23 (16), 9105 2022
    Citations: 7

  • Metabolic and proliferation evaluation of human adipose-derived mesenchymal stromal cells (ASC) in different culture medium volumes: standardization of static culture
    VA Simo, CP Evangelista-Ribeiro, H Brand, L Lagass-Pereira, ...
    Biologicals 62, 93-101 2019
    Citations: 7

  • Nandrolone decanoate causes uterine injury by changing hormone levels and sex steroid receptors in a dose-and time-dependent manner
    VA Simao, LAL Jnior, GAA Leite, ICC Camargo, LG de Almeida Chuffa
    Reproductive Toxicology 102, 98-108 2021
    Citations: 3

  • A busca pelo corpo perfeito vale a pena?: uma abordagem geral
    AEMC Silva, BR Souza, VA Simo, ICC Camargo
    Universidade Estadual Paulista (Unesp) 2015
    Citations: 3

  • Adipose-derived stem cells (ASCs) culture in spinner flask: improving the parameters of culture in a microcarrier-based system
    VA Simo, H Brand, RN da Silveira-Antunes, JT Fukasawa, J Leme, ...
    Biotechnology Letters 45 (7), 823-846 2023
    Citations: 2

  • Zuccari, DAPDC Melatonin Regulates the Daily Levels of Plasma Amino Acids, Acylcarnitines
    RP Junior, L Chuffa, VA Simo, NM Sonehara, R Chammas, RJ Reiter
    Biogenic Amines, Sphingomyelins, and Hexoses in a Xenograft Model of Triple 2022
    Citations: 2

  • Estabelecimento de um bioprocesso para proliferao de clulas estromais mesenquimais derivadas de tecido adiposo humano em biorreator
    VA Simo
    Universidade de So Paulo 2020
    Citations: 1

  • Avaliao do ciclo estral, tecido ovariano e uterino e parmetros fetais de ratas Wistar tratadas com Topiramato
    ICC Camargo, WE Neres, APQ Mello, VA Simo
    Semina: Cincias Biolgicas e da Sade 37 (2), 55-70 2016
    Citations: 1