Mufeda Ali Jwad

reproductive physiology
Al-Nahrain University



, Master in applied embryology, PhD infertility and clinical reproduction


Embryology, Embryology, Obstetrics and Gynecology, Medicine


Scopus Publications

Scopus Publications

  • The impact of serum and follicular fluid secreted frizzled-related protein-5 on ICSI outcome in Iraqi infertile women with different body mass index
    Hameedah Abdul Hussein Mohsin, Hayder A. L. Mossa, and Mufeeda Ali Jawad

    Indian Association of Biomedical Scientists
    Introduction and Aim: Adipose tissue adipokines and cytokines impede oocyte maturation and endometrial epithelial receptivity. Secreted frizzled-related protein 5 (Sfrp5), a novel antagonist adipokine secreted by adipocytes, may have anti-inflammatory and insulin-sensitizing actions, but data is conflicting. This study examined serum and follicular fluid Sfrp5 levels in Iraqi infertile women with varying BMIs undergoing IVF/ICSI, as well as ICSI outcomes.   Materials and Methods: This prospective cross-sectional study comprised 90 infertile females aged 18–45 who underwent IVF/ICSI at the High Institute of Infertility Diagnosis and Assisted Reproductive Technologies Centre in Baghdad, Iraq. Participants received antagonist ovarian hyperstimulation. All individuals' blood fasting sugar, serum fasting insulin, serum, and follicular fluid SFRP5 were tested on oocyte retrieval day. HOMA-IR was computed. Oocyte maturity and embryo morphology were categorized. Serum B-hCG was measured 14 days after embryo transfer.   Results: A notable disparity was observed in the levels of serum and follicular Sfrp5, total oocyte count, mean metaphase II (MII), grade I, and pregnancy rate (p<0.05) among the participants categorized as normal weight, overweight, and obese. A notable disparity was observed in the average germinal vesicles (GV), grade III (GIII) embryos, and HOMA-IR (p < 0.05) among patients with varying body mass index (BMI) values. The study found a positive correlation between the levels of Sfrp5 in both serum and follicular fluid and the total count of oocytes, MII oocytes, grade I embryos, and pregnancy rate. However, there was a negative correlation between Sfrp5 levels and HOMA-IR, with statistical significance at p<0.05.   Conclusion: Increased BMI is associated with lower serum and follicular fluid Sfrp5, reduced total oocyte count, reduced metaphase II oocyte count, more germinal vesicle oocytes, reduced embryo quality and lower pregnancy rate. Serum and follicular fluid Sfrp5 levels are negatively correlated with HOMA-IR but positively associated with ICSI outcome.

  • Effect of Bisphenol A Level in Follicular Fluid on ICSI OutCome
    Sarah Hamza Herez, M. A. Jawad and Muayad Sraibit Abbood

    Siree Journals
    Background: Infertility is the disability of a couple to obtain pregnancy after one year of sexual intercourse that is unprotected and regular. Bisphenol A (BPA) is an industrial chemical, that is produced in huge quantities worldwide. It is utilized as a raw material in multiple industries, and assorted as one of the endocrine-disrupting chemicals, as it can interfere with hormone activity. Bisphenol A may have a role in the reproduction process and may impact oocyte's maturity, meiotic division of germ cells, or fertilization rate. This study aimed to assess the impact of Bisphenol A level in follicular fluid on ICSI outcome. Methodology: The study was conducted at the High Institute for Infertility Diagnosis and Assisted Reproductive Technologies / Al Nahrain University, Baghdad /Iraq, at the interval extending from October 2021 to April 2022. Sixty infertile women enrolled in this study . BPA levels in follicular fluid were evaluated through an enzyme-linked immunosorbent assay (ELISA) technique. Results: Of 60 patients enrolled in this study, 22 patients (36.3%) became pregnant. Bisphenol A was detected in follicular fluids (FF) of all patients. The mean follicular fluid BPA level was significantly lower in pregnant women in comparison with that of non-pregnant women (45.44±1.73 ng/ml versus 68.23±6.77 ng/ml, respectively P = 0.01). A significant positive correlation was detected between BPA levels in follicular fluid and Grade 3embryos (r=0.539, p=0.021). Conclusion: Bisphenol A can be detected in follicular fluids of all patients undergoing IVF ̸ ICSI. Elevated BPA levels in the follicular fluid may affect IVF̸ ICSI outcomes (embryo quality and pregnancy rate).

  • Effect of intrauterine flushing of hcg on day of trigger on iui outcome


  • Comparison between effects of ketamine and remifentanil used during oocyte retrieval on ICSI outcome
    Systematic Reviews in Pharmacy SynthesisHub Advance Scientific Research

  • Antiatherosclerotic effect of L-thyroxine and verapamil combination on thoracic aorta of hyperlipidemic rabbits

  • Effect of alcohol extract of Prunus avium on In vitro sperm activation of human semen samples