Iron deficiency among primary school children in Mosul City /Northern Iraq, a cross-section study Nashwan Mustafa Al Hafidh, Elham Khattab Al-Jammas, Humam Zubeer Journal of the Pakistan Medical Association, 2024 Objective: To determine the prevalence of iron deficiency among primary school students in an urban setting.Method: The descriptive, cross-sectional study was conducted from January to April 2019 in Mosul, Iraq, after approval from the ethics review committee of the College of Medicine, Nineveh University, Iraq, and comprised students aged 6-12 years who were part of the 2018-19 academic year at 4 public primary schools located along the two banks of Tigris River. Serum ferritin was measured in all the participants. Data wa analysed using Minitab 20.Results: Of the 827 subjects, 439(53%) were girls and 388(47%) were boys. The overall mean age was 8.5±0.057 years, with 558(67.5%) aged <10 years. The mean serum ferritin level was 8.05±6.43ng/ml, and 173(20.92%) subjects were found to iron-deficient. Among the iron-deficient students, 87(50.29%) had iron deficiency anaemia and 86(49.71%) had non-anaemic iron deficiency. Age and gender were significantly different between students with anaemic and non-anaemic iron deficiency (p<0.05). Within boys, significant difference was also noted in terms of body mass index-for-age values (p<0.05).Conclusion: One-fifth of the students were found to have iron deficiency. Plans to control iron deficiency among young children are essential.Key Words: Anaemia, Iron-Deficiency, Ferritins
Serum ferritin status and mitochondrial function in children Elham KhAljammas, Muhammed A Ahmed Al Kataan, Nashwan M Al Hafidh Bangladesh Journal of Medical Science, 2023 objective: Iron is the most abundant metal within the mitochondrial matrix . Ferritin reflects bodyironstores. This study aimed to assess the association between serum ferritin levels and mitochondrial function in children. Methods: Two hundred and forty-three children from four governmental primary schools in Mosul city in Iraq were randomly selected by a multistage random sampling method. Their age range was 6-12 years. Mitochondrial function tests involved measurement of serum lactate, serum pyruvate, and L-Carnitine were analyzed in all selected children along with serum ferritin. Results: Lower levels of serum ferritin weresignificantly associated with higher levels of serum lactate, serum lactate/serum pyruvate ratio. There was a significant negative correlation (p = 0.000, - 0.296,- 0.286) between mean serum ferritin level and mean serum lactate, serum lactate / serum pyruvate ratio respectively.There were significant differences (p= 0.000) in mean serum level of mitochondrial function tests (Lactate, L- Carnation, and L/P ratio) in comparing children possessing a normal level of serum ferritin versus those with a low serum ferritin level of < 12 ng/ml. ROC analysis showed that when the area under the curve (AUC) was 0.761 ± SE 0.37, a cut off value 4.79 ng/ml of serum ferritin was significantly (p=0 .000) associated with sensitivity of 100 % and 1- specificity of 0.861 value with presence of L: P molar ratio of ≤ equal 20. Conclusion:Serum ferritin < 12 ng/ ml represntsmitochondrial deficient level. Serum ferritin < 4.79 ng/ml was the critical value at which only 8.6% of children will have a healthy mitochondrial function. Bangladesh Journal of Medical Science Vol. 22 No. 02 April’23 Page : 374-378
Vitamin d deficiency among primary school children in mosul city, northern iraq Malaysian Journal of Medicine and Health Sciences, 2021
Effect of pacifier use on feeding practice in early infancy Nashwan M. Al-Hafidh, Faris B. Al-sawaf, Rafida H. Khalaf Annals of Tropical Medicine and Public Health, 2020 Many local breast-feeding infants were observed using pacifiers during first month of life. This study aimed to assess the effect of using pacifier during the period of breast-feeding establishment on breast-feeding weaning age.A case control study comparing 131 pacifier users' children during their first month of life versus 173 non-pacifier users in relation to breast feeding weaning age. Each enrolled child was ≥ 6 12 months age and was exclusive breast feeder for at leastthe first month oftheir life.One third (33.6 %) of pacifier user infants had pacifier in their first day of life; Male infant were significantly (p =0.004) more frequent pacifier users than female infants. Infants from extended family structure possessed 11.7 times risk to be a pacifier user (OR: 11.7, CI: 6.747-20.311).Nearly three quarter (71.8%) of pacifier users discontinued breast feeding prior to 6 months of age whereas abouttwo thirds (62.4 %) of pacifier not user maintained on breast feeding beyond age of 6 months (p = 0.000). Using a pacifier carried 4.2 times risk of early weaning from breast-feeding prior to 6 months of age (OR: 4.2, 95% CI 2.59-6.89).Factors that significantly predict early discontinuation of breast-feeding among studied variables were pacifier use, illiterate mother, and extended family structure.Pacifier use in the first month of life must be avoided to support longer than 6 months duration of breast-feeding.
Survival rate and mortality causes in patients with β-thalassemia major in Nineveh Governorate, Iraq Pakistan Journal of Medical and Health Sciences, 2020
Changes of liver transaminases levels during one year follow up of deferasirox treatment in children with β-thalassemia major Nashwan M Al Hafidh, Mozahim S Younis Bangladesh Journal of Medical Science, 2020 Objectives: Abnormal liver function tests lead to interruptions of Deferasirox therapy. The aim of this study is to determine the changes in liver transaminases levels in pediatric patients with β -thalassemia major during one year follow up of Deferasirox treatment.
 Material and methods: This study was conducted at Ibn Al Atheer center of thalassemia, Mosul city, Iraq during the period from 3rd of February 2013 till 2nd of February 2014. Seventy one pediatric patients with β -thalassemia major were included in the study. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were measured every 4 weeks after starting Deferasirox therapy dose of 30 mg /kg/day for one year.
 Results: In comparison to mean baseline ALT values, there were significant elevations of mean ALT values in each of the subsequent 4-weekly interval readingsafter Deferasirox therapy. There was nearly eleven times relative risk of having ALT ≥ 5 upper normal level (UNL) in patient with abnormal baseline ALT (Odd ratio 10.96,95% Confidence Interval: lower 2.05, upper 58.58). During a year of study, Deferasirox therapy was associated withALT readings of ≥ 5UNL in 22(31%) of pediatric β-thalassemia patients and that elevation lasted for 4 weeks in 95.5% of patients.
 Conclusions: Elevated ALT of ≥ 5UNL after Deferasirox therapy was short- lived, and lasted for 4 weeks in 95.5% of patients. It is advisable to start Deferasirox therapy at a dose of 30 mg /kg / day when baseline ALT level is normal.
 Bangladesh Journal of Medical Science Vol.19(3) 2020 p.453-457
Diagnostic yield of duodenal biopsy site in celiac disease in children Jordan Medical Journal, 2020
Vitamin D status and mitochondrial function in children Jordan Medical Journal, 2020
EFFICACY OF INTERRUPTED AND MODIFIED DEFERASIROX DOSE AMONG PAEDIATRIC PATIENTS WITH Β- THALASSEMIA MAJOR AND HIGH ALANINE AMINOTRANSFERASE LEVEL Journal of Ayub Medical College, 2019
Efficacy of deferasirox median dose of 30 mg/kg/day in pediatric patients with β-thalassemia major during one year follows-up therapy Nashwan M Al-Hafidh, Mozahim S. Younis International Journal of Pharmaceutical Quality Assurance, 2019 Objective: To assess the efficacy of deferasirox median dose of 30 mg /kg /day in pediatric patients with β- thalassemia major during one year of follow up Patients and methods: This study was conducted at Ibn Al Atheer center of thalassemia, Mosul city, Iraq during the period from 3rd of February 2013 to 2nd of February 2014. Serum ferritin was measured at baseline and at four weekly intervals thereafter among 49 transfusion dependent children with β-thalassemia major, who were treated with median deferasirox dose of 30 mg /kg /day. Results: No statistically significant difference was detected between mean serum ferritin level at baseline (2189.39 ± 85.7) ng/mL and its mean value at four weekly intervals during forty-eight weeks of deferasirox therapy. There was significant (p = 0.027) improvement of serum ferritin at fifty – two weeks reading (1750.6 ± 202.8 ng/mL) compared to baseline reading. Percentage of patients with baseline serum ferritin levels of >2,500 ng/ml was 32.7% (16/49), which increased significantly (p=0.000) to 65% at four weeks of therapy, and ranged between 32.1% - 46.2 % in the remaining readings. Conclusions: There was no significant reduction of serum ferritin during initial forty-eight weeks of deferasirox median dose of 30 mg /kg /day among patient with baseline mean serum ferritin above 2000 ng /ml.
RECENT SCHOLAR PUBLICATIONS
Iron deficiency among primary school children in Mosul City/Northern Iraq, a cross-section study NM Al Hafidh, EK Al-Jammas, H Zubeer JPMA 74 (S227), 8 , 2024 2024.0 Citations: 1
Significance of Preoperative Clinical and Radiological Assessment in Diagnosing Foreign Body Aspiration in PediatricPatients NMAH Rasha Nadeem Ahmed, Bassam Khaleel Al-abbasi Thi_Qar Medical Journal (TQMJ) 27 (1), 28_40 , 2024 2024.0
Serum ferritin status and mitochondrial function in children E KhAljammas, MAA Al Kataan, NM Al Hafidh Bangladesh Journal of Medical Science 22 (2), 374-378 , 2023 2023.0 Citations: 1
New insight into risk factors for gastroesophageal reflux in infants NMAHMH Suleiman International Journal of Health Sciences 6 (S5), 9845–9852 , 2022 2022.0
Vitamin D Deficiency Among Primary School Children in Mosul City, Northern Iraq. EK Aljammas, NM Al-Hafidh, HGI Zubeer Malaysian Journal of Medicine & Health Sciences , 2021 2021.0 Citations: 3
Acute Diarrhea in Exclusively Breast Fed Infants in relation to Zinc Level RM Ibrahim, NM Al Hafidh Pak J Med Health Sci 15, 1431-5 , 2021 2021.0 Citations: 80
Diagnostic Yield of Duodenal Biopsy Site in Celiac Disease in Children NM Al-Hafidh, KT Al-Abachi, NMT Jawhar Jordan Medical Journal 54 (4) , 2020 2020.0
Vitamin D Status and Mitochondrial Function in Children. NM Al Hafidh, EK Aljammas, MA Al-Kataan Jordan Medical Journal 54 (4) , 2020 2020.0 Citations: 1
Changes of liver transaminases levels during one year follow up of Deferasirox treatment in children with β-thalassemia major MSY Nashwan M Al-Hafidh Bangladesh Journal of Medical Science 19 (03 July’20), 453-457 , 2020 2020.0 Citations: 2
Survival rate and mortality causes in patients with β-thalassemia major in Nineveh Governorate, Iraq NM Al-Hafidh, MS Younis, KF Al Taee EXECUTIVE EDITOR 11 (04), 443 , 2020 2020.0 Citations: 2
EFFICACY OF INTERRUPTED AND MODIFIED DEFERASIROX DOSE AMONG PAEDIATRIC PATIENTS WITH Î’-THALASSEMIA MAJOR AND HIGH ALANINE AMINOTRANSFERASE LEVEL NMAL Hafidh Journal of Ayub Medical College Abbottabad 31 (2), 182-184 , 2019 2019.0
Determinants of inappropriate complementary feeding practices in children aged 6-23 months in Mosul city NMAH Luay A. AL-waly The Medical Journal of Tikrit University 25 (1), 54-73 , 2019 2019.0 Citations: 1
Assessment of complementary feeding practice in children 6-23 months of age in Mosul city NMAH AL-Waly, Luay Amjed Mosul Journal of Nursing 2 (1), 13-18 , 2014 2014.0 Citations: 1
Double-surface intensive phototherapy versus single-surface conventional phototherapy in treatment of neonatal hyperbilirubinemia RSS Nashwan M. Al-Hafidha , Ziad K. Ali b Ann. Coll. Med. Mosul 39 (1), 25-31 , 2013 2013.0 Citations: 7
β thalassemia major patients profile in Ninevah governorate-Iraq. MA Al-Nuaimi, YA AL-Hially, N AL-Hafidh Tikrit Medical Journal 18 , 2012 2012.0 Citations: 7
Value of clinical data in diagnosis of symptomatic celiac disease in children N M Al-Hafidh Annals of the College of Medicine, Mosul 38 (1), 46-53 , 2012 2012.0
Value of IgA human recombinant tissue transglutaminase antibody test in diagnosis of symptomatic celiac disease in children KT Al-Abachi, NM Al-Hafidh Annals of the College of Medicine Mosul 36 (1), 79.0-85.0 , 2010 2010.0
EFFECT OF PACIFIER USE ON FEEDING PRACTICE IN EARLY INFANCY NM Al-Hafidh, FB Al-sawaf, RH Khalaf
Efficacy of Deferasirox Median Dose of 30 mg/kg/day in Pediatric Patients with β-Thalassemia Major during One Year Follows-up Therapy NM Al-Hafidh, MS Younis Quality Assurance 10 (3), 69-72 , 0
MOST CITED SCHOLAR PUBLICATIONS
Acute Diarrhea in Exclusively Breast Fed Infants in relation to Zinc Level RM Ibrahim, NM Al Hafidh Pak J Med Health Sci 15, 1431-5 , 2021 2021.0 Citations: 80
Double-surface intensive phototherapy versus single-surface conventional phototherapy in treatment of neonatal hyperbilirubinemia RSS Nashwan M. Al-Hafidha , Ziad K. Ali b Ann. Coll. Med. Mosul 39 (1), 25-31 , 2013 2013.0 Citations: 7
β thalassemia major patients profile in Ninevah governorate-Iraq. MA Al-Nuaimi, YA AL-Hially, N AL-Hafidh Tikrit Medical Journal 18 , 2012 2012.0 Citations: 7
Vitamin D Deficiency Among Primary School Children in Mosul City, Northern Iraq. EK Aljammas, NM Al-Hafidh, HGI Zubeer Malaysian Journal of Medicine & Health Sciences , 2021 2021.0 Citations: 3
Changes of liver transaminases levels during one year follow up of Deferasirox treatment in children with β-thalassemia major MSY Nashwan M Al-Hafidh Bangladesh Journal of Medical Science 19 (03 July’20), 453-457 , 2020 2020.0 Citations: 2
Survival rate and mortality causes in patients with β-thalassemia major in Nineveh Governorate, Iraq NM Al-Hafidh, MS Younis, KF Al Taee EXECUTIVE EDITOR 11 (04), 443 , 2020 2020.0 Citations: 2
Iron deficiency among primary school children in Mosul City/Northern Iraq, a cross-section study NM Al Hafidh, EK Al-Jammas, H Zubeer JPMA 74 (S227), 8 , 2024 2024.0 Citations: 1
Serum ferritin status and mitochondrial function in children E KhAljammas, MAA Al Kataan, NM Al Hafidh Bangladesh Journal of Medical Science 22 (2), 374-378 , 2023 2023.0 Citations: 1
Vitamin D Status and Mitochondrial Function in Children. NM Al Hafidh, EK Aljammas, MA Al-Kataan Jordan Medical Journal 54 (4) , 2020 2020.0 Citations: 1
Determinants of inappropriate complementary feeding practices in children aged 6-23 months in Mosul city NMAH Luay A. AL-waly The Medical Journal of Tikrit University 25 (1), 54-73 , 2019 2019.0 Citations: 1
Assessment of complementary feeding practice in children 6-23 months of age in Mosul city NMAH AL-Waly, Luay Amjed Mosul Journal of Nursing 2 (1), 13-18 , 2014 2014.0 Citations: 1
Significance of Preoperative Clinical and Radiological Assessment in Diagnosing Foreign Body Aspiration in PediatricPatients NMAH Rasha Nadeem Ahmed, Bassam Khaleel Al-abbasi Thi_Qar Medical Journal (TQMJ) 27 (1), 28_40 , 2024 2024.0
New insight into risk factors for gastroesophageal reflux in infants NMAHMH Suleiman International Journal of Health Sciences 6 (S5), 9845–9852 , 2022 2022.0
Diagnostic Yield of Duodenal Biopsy Site in Celiac Disease in Children NM Al-Hafidh, KT Al-Abachi, NMT Jawhar Jordan Medical Journal 54 (4) , 2020 2020.0
EFFICACY OF INTERRUPTED AND MODIFIED DEFERASIROX DOSE AMONG PAEDIATRIC PATIENTS WITH Î’-THALASSEMIA MAJOR AND HIGH ALANINE AMINOTRANSFERASE LEVEL NMAL Hafidh Journal of Ayub Medical College Abbottabad 31 (2), 182-184 , 2019 2019.0
Value of clinical data in diagnosis of symptomatic celiac disease in children N M Al-Hafidh Annals of the College of Medicine, Mosul 38 (1), 46-53 , 2012 2012.0
Value of IgA human recombinant tissue transglutaminase antibody test in diagnosis of symptomatic celiac disease in children KT Al-Abachi, NM Al-Hafidh Annals of the College of Medicine Mosul 36 (1), 79.0-85.0 , 2010 2010.0
EFFECT OF PACIFIER USE ON FEEDING PRACTICE IN EARLY INFANCY NM Al-Hafidh, FB Al-sawaf, RH Khalaf
Efficacy of Deferasirox Median Dose of 30 mg/kg/day in Pediatric Patients with β-Thalassemia Major during One Year Follows-up Therapy NM Al-Hafidh, MS Younis Quality Assurance 10 (3), 69-72 , 0
