Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease L Huang, P Liu, Q Chen, K Hu, S Li, A Lee, M Wabitsch, LJ Zhu, Q Yu, ... Science Advances 12 (17), eaed2780 , 2026 2026
Brown fat-selective adipokines YX Wang, Q Chen US Patent App. 19/250,645 , 2025 2025
Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis N Bhalerao, Y Ogoti, J Peura, C Johnson, Q Chen, ED Korobkina, ... bioRxiv , 2025 2025 Citations: 2
UCP1 Mitigates Hepatic Steatosis and Fibrosis Independent of Cold Exposure JA Haley, J Le, R Li, ED Korobkina, F De Fatima Silva, M Gaughan, ... bioRxiv, 2025.08. 05.666925 , 2025 2025
Rag GTPases Suppress Renal Cystic Disease by Inhibiting TFEB Independently of mTORC1 F de Fatima Silva, AR Boucher Jr, H Li, Q Chen, M Gaughan, ... bioRxiv , 2025 2025
A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite L Huang, P Liu, Y Du, JF Bazan, D Pan, Q Chen, A Lee, VSR Kola, ... bioRxiv, 2023.09. 12.557454 , 2024 2024 Citations: 5
Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress ED Korobkina, CM Calejman, JA Haley, ME Kelly, H Li, M Gaughan, ... Nature metabolism 6 (11), 2187-2202 , 2024 2024 Citations: 23
Abstract B002: Tumor-secreted PTHrP facilitates pancreatic cancer cachexia by regulation of de novo lipogenesis pathway N Bhalerao, J Peura, Y Ogoti, C Johnson, Q Chen, E Korobkina, F Keller, ... Cancer Research 84 (17_Supplement_2), B002 , 2024 2024
Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis G Park, JA Haley, J Le, SM Jung, TP Fitzgibbons, ED Korobkina, H Li, ... Nature Metabolism, 1204–1220 , 2023 2023 Citations: 81
A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis Q Chen, L Huang, D Pan, K Hu, R Li, RH Friedline, JK Kim, LJ Zhu, ... Nature communications 13 (1), 7633 , 2022 2022 Citations: 29
A novel batokine Breg controls adipose thermogenesis and glucose homeostasis Q Chen, L Huang, D Pan, K Hu, R Li, LJ Zhu, DA Guertin, YX Wang bioRxiv, 2022.08. 16.504121 , 2022 2022 Citations: 2
Cbx4 sumoylates Prdm16 to regulate adipose tissue thermogenesis Q Chen, L Huang, D Pan, LJ Zhu, YX Wang Cell reports 22 (11), 2860-2872 , 2018 2018 Citations: 49
IRX3 promotes the browning of white adipocytes and its rare variants are associated with human obesity risk Y Zou, P Lu, J Shi, W Liu, M Yang, S Zhao, N Chen, M Chen, Y Sun, ... EBioMedicine 24, 64-75 , 2017 2017 Citations: 65
Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation L Huang, D Pan, Q Chen, LJ Zhu, J Ou, M Wabitsch, YX Wang Nature communications 8 (1), 68 , 2017 2017 Citations: 50
Arogenate dehydratase isoforms differentially regulate anthocyanin biosynthesis in Arabidopsis thaliana Q Chen, C Man, D Li, H Tan, Y Xie, J Huang Molecular plant 9 (12), 1609-1619 , 2016 2016 Citations: 95
Arabidopsis thylakoid formation 1 is a critical regulator for dynamics of PSII–LHCII complexes in leaf senescence and excess light W Huang, Q Chen, Y Zhu, F Hu, L Zhang, Z Ma, Z He, J Huang Molecular plant 6 (5), 1673-1691 , 2013 2013 Citations: 92
Arogenate dehydratase isoforms differentially regulate anthocyanin biosynthesis in Arabidopsis thaliana Q Chen, C Man, D Li, H Tan, Y Xie, J Huang Molecular plant 9 (12), 1609-1619 , 2016 2016 Citations: 95
Arabidopsis thylakoid formation 1 is a critical regulator for dynamics of PSII–LHCII complexes in leaf senescence and excess light W Huang, Q Chen, Y Zhu, F Hu, L Zhang, Z Ma, Z He, J Huang Molecular plant 6 (5), 1673-1691 , 2013 2013 Citations: 92
Quantitative analysis of metabolic fluxes in brown fat and skeletal muscle during thermogenesis G Park, JA Haley, J Le, SM Jung, TP Fitzgibbons, ED Korobkina, H Li, ... Nature Metabolism, 1204–1220 , 2023 2023 Citations: 81
IRX3 promotes the browning of white adipocytes and its rare variants are associated with human obesity risk Y Zou, P Lu, J Shi, W Liu, M Yang, S Zhao, N Chen, M Chen, Y Sun, ... EBioMedicine 24, 64-75 , 2017 2017 Citations: 65
Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation L Huang, D Pan, Q Chen, LJ Zhu, J Ou, M Wabitsch, YX Wang Nature communications 8 (1), 68 , 2017 2017 Citations: 50
Cbx4 sumoylates Prdm16 to regulate adipose tissue thermogenesis Q Chen, L Huang, D Pan, LJ Zhu, YX Wang Cell reports 22 (11), 2860-2872 , 2018 2018 Citations: 49
A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis Q Chen, L Huang, D Pan, K Hu, R Li, RH Friedline, JK Kim, LJ Zhu, ... Nature communications 13 (1), 7633 , 2022 2022 Citations: 29
Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress ED Korobkina, CM Calejman, JA Haley, ME Kelly, H Li, M Gaughan, ... Nature metabolism 6 (11), 2187-2202 , 2024 2024 Citations: 23
A brown fat-enriched adipokine, ASRA, is a leptin receptor antagonist that stimulates appetite L Huang, P Liu, Y Du, JF Bazan, D Pan, Q Chen, A Lee, VSR Kola, ... bioRxiv, 2023.09. 12.557454 , 2024 2024 Citations: 5
Pancreatic cancer cachexia is mediated by PTHrP-driven disruption of adipose de novo lipogenesis N Bhalerao, Y Ogoti, J Peura, C Johnson, Q Chen, ED Korobkina, ... bioRxiv , 2025 2025 Citations: 2
A novel batokine Breg controls adipose thermogenesis and glucose homeostasis Q Chen, L Huang, D Pan, K Hu, R Li, LJ Zhu, DA Guertin, YX Wang bioRxiv, 2022.08. 16.504121 , 2022 2022 Citations: 2
Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease L Huang, P Liu, Q Chen, K Hu, S Li, A Lee, M Wabitsch, LJ Zhu, Q Yu, ... Science Advances 12 (17), eaed2780 , 2026 2026
Brown fat-selective adipokines YX Wang, Q Chen US Patent App. 19/250,645 , 2025 2025
UCP1 Mitigates Hepatic Steatosis and Fibrosis Independent of Cold Exposure JA Haley, J Le, R Li, ED Korobkina, F De Fatima Silva, M Gaughan, ... bioRxiv, 2025.08. 05.666925 , 2025 2025
Rag GTPases Suppress Renal Cystic Disease by Inhibiting TFEB Independently of mTORC1 F de Fatima Silva, AR Boucher Jr, H Li, Q Chen, M Gaughan, ... bioRxiv , 2025 2025
Abstract B002: Tumor-secreted PTHrP facilitates pancreatic cancer cachexia by regulation of de novo lipogenesis pathway N Bhalerao, J Peura, Y Ogoti, C Johnson, Q Chen, E Korobkina, F Keller, ... Cancer Research 84 (17_Supplement_2), B002 , 2024 2024