Mohsen Dehghani

@mums.ac.ir

Department of Epidemiology
Department of Epidemiology, Mashhad University of Medical Sciences, Mashhad, Iran

Mohsen Dehghani
Mohsen Dehghani is Assistant Professor of Epidemiology at Mashhad University of Medical Sciences from 2023. He was also academic staff of Epidemiology at Shahroud University of Medical Sciences from 2012 to 2015.
Mohsen Dehghani, BSc in Public Health from Tehran University of Medical Sciences, MSc in Epidemiology from Isfahan University of Medical Sciences, and graduated PhD in Epidemiology from Iran University of Medical Sciences.
He interested in Systematic Review and Network Meta-Analysis, Diabetes Epidemiology, Pharmacoepidemiology, and Evidence Based Medicine/Evidence synthesis.

EDUCATION

Mohsen Dehghani is Assistant Professor of Epidemiology at Mashhad University of Medical Sciences from 2023. He was also academic staff of Epidemiology at Shahroud University of Medical Sciences from 2012 to 2015.
Mohsen Dehghani, BSc in Public Health from Tehran University of Medical Sciences, MSc in Epidemiology from Isfahan University of Medical Sciences, and graduated PhD in Epidemiology from Iran University of Medical Sciences.
He interested in Systematic Review and Network Meta-Analysis, Diabetes Epidemiology, Pharmacoepidemiology, and Evidence Based Medicine/Evidence synthesis.

RESEARCH, TEACHING, or OTHER INTERESTS

Epidemiology, Health Professions, Endocrinology, Internal Medicine

FUTURE PROJECTS

Pharmacoepidemiology


Applications Invited

Network meta-analysis


Applications Invited

Evidence synthesis


Applications Invited
44

Scopus Publications

1389

Scholar Citations

18

Scholar h-index

23

Scholar i10-index

Scopus Publications

  • Hospital information systems evaluation criteria: a scoping review
    Hediye Khorasani, Soheila Damiri, Samaneh Abbasi, Amirhossein Fathabadi, Mohsen Dehghani, Masoumeh Sadeghi
    BMC Health Services Research, 2026
    Hospital information systems (HISs) play a vital role in optimizing healthcare delivery, managing clinical data, and supporting decision-making. While numerous frameworks have been developed to evaluate HIS performance, many remain limited in scope and do not fully capture the wide range of needs in modern healthcare environments. This review aimed to identify, categorize, and present a comprehensive set of criteria for evaluating HIS performance. A scoping review was conducted following Arksey and O’Malley’s methodological framework and reported in line with the PRISMA-ScR guidelines. A systematic search was carried out in the Cochrane Library, PubMed, Scopus, Web of Science, and Google Scholar for English-language studies that addressed HIS evaluation criteria. The initial search yielded 561 records, 52 of which met the inclusion criteria. A comprehensive list of evaluation indicators was synthesized and grouped into six main domains: human, technological, informational, organizational, legal, and patient safety. These domains were further divided into 14 categories. To provide further clarity, the indicators were also classified according to Donabedian’s framework of structure, process, and outcome. The majority of studies emphasized structural aspects—such as technological infrastructure and organizational capacity—followed by process-related factors such as user training and system usability, whereas outcome measures were less frequently addressed. Across the domains, “user satisfaction” was the most commonly reported criterion. This review provides a structured, multidimensional framework for the comprehensive evaluation of HISs. Moving beyond partial assessments focused solely on technical or usability aspects highlights the importance of incorporating human, organizational, legal, and patient safety perspectives. The proposed framework has practical value for policymakers, hospital administrators, and IT developers and can serve as a foundation for developing standardized and adaptable evaluation tools.
  • Clinical and functional outcomes of subacromial spacer implantation and superior capsular reconstruction for massive irreparable rotator cuff tears: a systematic review and meta-analysis
    Naeemeh Kalali, Mohammad H. Ebrahimzadeh, Mohsen Dehghani, Ali Moradi, Mahdieh Sahebi, Nafiseh Jirofti
    BMC Musculoskeletal Disorders, 2026
    BACKGROUND: Various surgical techniques are available for treating Massive and Irreparable Rotator Cuff Tears (MIRCTs). However, there is no agreement on which approach is the most effective. We have conducted a systematic review and analyzed the clinical outcomes of two advanced procedures: Subacromial Spacer Implantation (SSI) and Arthroscopic Superior Capsular Reconstruction (ASCR) for managing MIRCTs. METHODS: A comprehensive search using MeSH and keywords was performed on Medline/ PubMed, Embase, Web of Science, Scopus, and Cochrane Database up to August 2023 for observational and pre-post clinical trials regarding the study outcomes. American Shoulder and Elbow Score (ASES), Constant score (CS), Visual Analogue Scale (VAS), University of California-Los Angeles (UCLA), Simple Shoulder Test (SST), Subjective Shoulder Value (SSV), Japanese Orthopaedic Association (JOA), and Range of Motion (ROM) were considered as clinical and functional outcomes. The retrieved studies were assessed for methodological quality. Random-effects meta-analysis was used to estimate the pooled Weighted Mean Difference (WMD) with a 95% confidence interval (CI), considering the clinical and methodological heterogeneity across studies. We also performed subgroup meta-analysis and sensitivity analysis. RESULTS: Findings of the meta-analysis on 35 pre-post clinical trials, mainly fair to good quality, showed that clinical scores significantly improve after ASCR, ASES (WMD: 40.76; 95% CI: 35.9 to 45.6), CS (WMD: 33.34; 95% CI: 24.2 to 42.3), and VAS (WMD: -4.30; 95% CI: -4.8 to -3.7). The ROM reached 45.83 (95% CI: 33.6 to 58) for abduction, 42.8 (95% CI: 28.6 to 56.9) for flexion, 0.13 (95% CI: -1.5 to 1.8) for internal rotation, and 11.5 (95% CI: 7.5 to 15.4) for external rotation after surgery. The acromiohumeral distance (AHD) increased by 2.69 mm (95% CI: 1.9 to 3.4 mm). We found no publication bias, and the meta-analysis findings were robust in sensitivity analysis. CONCLUSIONS: Two advanced procedures, SSI and ASCR, for patients with MIRCTs showed significantly improved clinical and functional outcomes. It is difficult to directly compare the effectiveness of these two procedures. More long-term, large-scale, and high-quality trials are needed to confirm their effectiveness.
  • Epidemiological pattern of death and causes of death in registered immigrants of Northeast Iran during the 2013–2023: a cross-sectional study
    Samaneh Eslami, Ehsan Mosa Farkhani, Masoumeh Sadeghi, Masoumeh Andish, Najmeh Khodadadi, Mohsen Dehghani
    BMC Public Health, 2026
    International migration has increased in recent years and yet there is limited information about immigrant mortality. The present study aimed to investigate the epidemiological pattern of death and their causes among registered immigrants in Mashhad city, northeast Iran. In this cross-sectional study, data on deceased Afghan immigrants registered according to the International Classification of Diseases (ICD-10) were extracted from the system of registration and classification of the causes of death of Iran for deaths due to causes related to non-communicable diseases, communicable diseases, maternal/neonatal causes, injuries and unknown along with subgroups of each cause during the years 2013–2023. The variables analyzed included age, gender, date and cause of death. Patterns of death and age/gender standardized mortality rates were calculated. Data analysis was performed using Stata software. Data from 10,777 deaths were analyzed. The crude mortality rate was 3.05 per 1,000 population per year, while the age and gender standardized mortality rate (using the direct method and WHO 2000–2025 standard population) was 5.42 per 1,000 (95% CI: 5.31–5.54). Over this decade, non-communicable diseases were the leading cause of death among immigrants, accounting for 51.11%, followed by communicable diseases (24.27%), maternal/neonatal causes (10.44%), injuries (9.62%) and unknown causes (4.56%), respectively. Maternal/neonatal causes were more prevalent in males with 617 cases than females with 508 cases. Injuries were more common in males (n = 831) and predominantly affected the 20–40 age group with 40.04%. Among non-communicable diseases, circulatory system diseases (n = 3396) were the most frequent, followed by neoplasms (n = 839). A significant difference was observed between the occurrence of each cause of death and both age (p < 0.001) and gender (p < 0.001). Mortality due to non-communicable diseases, particularly circulatory system diseases and neoplasms, was higher among immigrants than other causes of death. Understanding and recording comprehensive and accurate data on the causes of death in migrant populations is crucial. Also, Addressing the health needs of migrants remains a major challenge due to the various risks associated with migration. Therefore, clinicians, health managers and policymakers involved in immigrant health require enhanced knowledge as a foundation for evidence-based care and informed decision-making.
  • Investigating the nutritional and mental health status in the suburbs of Northeast Iran: a register-based study
    Masoumeh Andish, Ehsan Mosa Farkhani, Ali Taghipoor, Samaneh Eslami, Zahra Amiri, Najmeh Khodadadi, Mohsen Dehghani
    BMC Public Health, 2026
    BACKGROUND: In urban areas, particularly among informal settlements, malnutrition and mental health disorders are recognized as key indicators of social inequality. Child malnutrition encompasses a wide range of developmental disorders. Mental disorders are also considered one of the main causes of the global burden of disease. This study aimed to investigate the nutritional status in children, mental health, and exposure to domestic violence among mothers living in the marginalized areas of Mashhad, northeast Iran. METHODS: This cross-sectional study analyzed data from 325863 individuals (children and mothers) living in the marginalized areas of Mashhad, registered in the Sina Electronic Health Record SINAEHR) system between 2016 and 2018. National reference standard values for underweight (weight-for-age), stunting (height-for-age), wasting, overweight, and obesity (weight-for-height) were used to define nutritional status. Binary and multinomial logistic regression models were applied to explore the associated factors with nutritional and mental health status. Data analysis was performed using SPSS software version 26. RESULTS: A total, 51.2% were boys and 48.8% were girls. Children with abnormal TSH were 20% more likely to be Stunting. Girls were 14% more likely to be underweight than boys (AOR = 1.14; 95% CI: 1.07-1.23). Maternal education and employment played a protective role in children's nutritional indicators. Regarding mental health and domestic violence indicators, smoking was associated with an increased likelihood of developing mental health problems (AOR = 3.58; 95% CI: 3.26-3.93). No statistically significant association was found between alcohol consumption and domestic violence; mothers with low scores on the mental health assessment were more likely to experience domestic violence, and a significant association was observed in this regard. CONCLUSIONS: Malnutrition and mental health problems remain significant challenges among children and mothers in marginalized areas. Strengthening maternal support, early identification, and integrated health interventions are crucial to reduce these disparities.
  • Systemic Low Dose Corticosteroid Improves Early Postoperative Knee Function and Pain Intensity in Patients Undergoing Unilateral Total Knee Arthroplasty: A Blinded Controlled Randomized Clinical Trial
    Mohammad H. Ebrahimzadeh, Reza Ganji, Mahdieh Samei, Mohsen Dehghani, Moslem Fallah, Mohammad Mahdi Sarzaeem, Hadi Makhmalbaf, Shayan Zanjanian, Mahla Daliri, Masoumeh Salari, Amir Kachooei
    Jbjs Open Access, 2026
    Background: This randomized controlled trial evaluates low-dose oral corticosteroids for improving pain and function after total knee arthroplasty (TKA), leveraging their potent anti-inflammatory effects. Methods: A total of 102 patients who underwent primary unilateral TKA were randomized to receive either 400 mg of celecoxib plus 10 mg of oral prednisolone daily or 400 mg of celecoxib alone. Oral medications started after discharge (24-48 hours after surgery) and continuing for 2 weeks. Follow-up visits were conducted at 1, 2, 4, 12, and 24 weeks postsurgery. The Visual Analog Scale, range of motion (ROM), Knee Society Score, Oxford Knee Score, and sleep quality were evaluated. Results: Demographic data were similar, except for age, with celecoxib alone group being older (p = 0.005). The celecoxib + prednisolone group experienced significantly lower Visual Analog Scale pain scores at 1 week (mean difference [MD]: −0.81; 95% confidence interval [CI]: −1.59 to −0.03) and 2 weeks (MD: −0.99; 95% CI: −1.87 to −0.09) postoperatively. Age-adjusted results confirmed the reduction in pain with a slight difference, although it was not statistically significant. Knee function scores showed statistically significant improvement in the celecoxib + prednisolone group at 2 weeks (MD: 12.96; 95% CI: 0.21-26.13). Improvement in knee function scores was reduced by about half in age-adjusted analysis and was not statistically significant (MD: 6.25, p = 0.35). ROM demonstrated significant difference at 4 weeks (MD: 6.66; 95% CI: 0.44-12.86). Sleep quality showed significant improvement in the celecoxib + prednisolone group at 2 weeks (MD: 0.84; 95% CI: 0.05-1.64). Improvement was clinically confirmed by controlling for the effect of age with borderline significance. Uncertainty was observed due to wide CIs in some results. Conclusion: Oral low-dose prednisolone administered early after TKA resulted in significant reductions in pain and improvements in sleep quality, ROM, and Knee Society Score during the early postoperative period. However, these improvements did not consistently reach the minimal clinically important difference. Adjusted analyses accounting for age suggested modest benefits, but wide CIs and small effect sizes warrant cautious interpretation. To optimize dosing regimens and assess the long-term effects of oral corticosteroids in TKA recovery protocols, large-scale randomized controlled trials are necessary. Level of Evidence: Therapeutic Level I . See Instructions for Authors for a complete description of levels of evidence.
  • Mesenchymal Stem Cell Transplantation for Osteogenesis Imperfecta Patients: A Systematic Review
    Mohaddese Mohaddesi Khorasani, Mohammad Hossein Ebrahimzadeh, Mohsen Dehghani, Maedeh Sharafoddin, Ali Moradi, Nafiseh Jirofti
    Annals of the New York Academy of Sciences, 2025
    The following systematic review provides an evaluation of the effectiveness of mesenchymal stem cell (MSC) transplantation in the treatment of osteogenesis imperfecta (OI). After reviewing 40 studies, 9 human clinical studies that included case reports or case series were included and resulted in a total of 12 patients with OI. Five studies documented an increase in total body bone mineral (TBBM) content, whereas four studies observed a reduction in fracture rates post‐transplantation. Moreover, noticeable improvements in children's growth were recorded. Although both BMSCs and human fetal MSCs (hfMSCs) were found to be effective, studies involving BMSCs were rated higher in terms of methodological quality. Both BMSCs and hfMSCs demonstrated significant improvements in TBBM, growth rates, and fracture reduction, with BMSC studies scoring higher in methodological quality. Future randomized clinical trials with longer follow‐ups are necessary.
  • Clinical outcomes of artificial meniscus scaffolds for partial meniscus injury: a systematic review and meta-analysis
    Afsaneh Jahani, Mohammad Hossein Ebrahimzadeh, Mohsen Dehghani, Maedeh Sharafoddin, Ali Moradi, Fateme Nikbakht, Nafiseh Jirofti
    Knee Surgery and Related Research, 2025
    Background Meniscal injuries, involving damage to the critical fibrocartilaginous structure of the knee joint, often necessitate surgical intervention, including meniscal allograft transplantation or the use of commercial implants. Despite advances in implant based therapies, there is no consensus regarding the comparative efficacy of collagen meniscus implants (CMI) versus polyurethane-based (PU-based) scaffolds. This review aimed to systematically evaluate and compare the clinical outcomes associated with these two implant types for partial meniscal repair. Methods A comprehensive systematic review was conducted to evaluate the clinical outcomes of meniscal implants by searching multiple databases including Medline/PubMed, Web of Science, Embase, Scopus, and Cochrane in the temporal range of 1999–2024. The review focused on pre–post studies and assessed various patient-reported outcome measures, including the visual analog scale (VAS), international Knee Documentation Committee (IKDC), Lysholm, knee injury and osteoarthritis outcome score (KOOS), as well as the Tegner activity score. These outcomes were evaluated across different follow-up periods [short-term (6 month to 2.5 years), mid-term (2.5–5 years) and long-term (10 years)] following meniscal implant implantation. A random-effects meta-analysis model was used to address heterogeneity, along with a sensitivity analysis to evaluate the robustness of pooled estimates. The National Institutes of Health (NIH) quality assessment tool was utilized to assess the methodological quality in the studies. Results The meta-analysis identified 26 studies that met the inclusion criteria, and the overall quality of the included studies was mostly fair to good. The analysis showed that both CMI and PU-based scaffolds improved clinical outcomes in patients with partial meniscus injuries, with the implants evaluated across short-term, mid-term, and long-term follow-up periods. Specifically, the analysis found: the VAS scores significantly improved during the short-term follow-up by an average of −1.86 points for CMI and −1.98 points for PU-based scaffolds. Lysholm scores significantly improved at short-term follow-up, increasing by an average of 29.26 points for CMI and 24.98 points for PU-based scaffolds. For the Tegner score, CMI implants showed an average increase of 2.02 points in the short-term, while PU-based implants exhibited a negligible change of −0.05 points. Conclusions Both CMI and PU-based scaffolds demonstrated improved clinical outcomes, but showed some differences in effectiveness over follow-up periods. PU-based scaffolds offer faster integration and short-term effectiveness, while CMI promotes gradual tissue regeneration and long-term stability. Although these differing characteristics support personalized meniscal repair strategies, the lack of comparative studies limits definitive clinical guidance. Level of evidence: Level III, IV.
  • Revolutionizing cancer diagnosis and dose biodistribution: a meta-analysis of [68ga] FAPI- 46 vs. [18f] FDG imaging
    Samaneh Abbasi, Mohsen Dehghani, Sara Khademi, Rasoul Irajirad, Zahra Pakdin Parizi, Mahdieh Sahebi, Masoumeh Sadeghi, Alireza Montazerabadi, Meysam Tavakoli
    Systematic Reviews, 2025
    Advancements in novel peptides significantly affect cancer diagnosis by targeting cancer-specific markers, thereby improving imaging modalities, such as positron emission tomography combined with computed tomography (PET/CT) for more accurate tumor detection. This systematic review and meta-analysis aimed to assess the diagnostic accuracy of [18F] Fluorodeoxyglucose (FDG) and 68Ga-fibroblast activation protein inhibitor (FAPI- 46) PET/CT for early cancer detection. A comprehensive search was conducted in Scopus, MEDLINE, Web of Science, and Embase databases up to March 28, 2024, using MeSH keywords. Titles and abstracts were screened to identify studies on hybrid [68Ga] FAPI- 46 and [18F] FDG, followed by a detailed full-text evaluation. Only cohort or cross-sectional studies published in English, focusing on the clinical diagnosis of cancer patients, were included, while reviews, case reports, conference proceedings, and abstracts were excluded. Random-effects meta-analysis was used for the estimation of pooled specificity and sensitivity with 95% confidence intervals (CIs). In addition, the heterogeneity was assessed across studies and subgroup meta-analyses for the detection rate via Stata. Among the 615 retrieved studies, nine articles were incorporated in the present systematic review, with five (n = 144 patients) eligible for meta-analysis. For [68Ga] FAPI- 46, the pooled sensitivity and specificity compared with immunohistopathology were 0.96 (95% CI 0.84, 0.99) and 0.92 (95% CI 0.53, 0.99), respectively, with a positive likelihood ratio (LR +) of 4.41 (95% CI 1.64, 11.79) and a negative likelihood ratio (LR −) of 3.07 (95% CI 1.01, 9.37). For [18F] FDG, pooled sensitivity and specificity compared with immunohistopathology were 0.73 (95% CI 0.34, 0.93) and 0.83 (95% CI 0.57, 0.95), with an LR + of 12.73 (95% CI 1.43, 113.45) and an LR − of 0.32 (95% CI 0.11, 0.17). The pooled odds ratio for the detection rate on a per-lesion basis was 1.73 (95% CI 0.99, 3.02) for [68Ga] FAPI- 46 compared with [18F] FDG. The pooled weighted mean differences in the standardized uptake value (SUVmax) for primary tumor uptake and the tumor-to-background ratio (TBR) in [68Ga] FAPI- 46 vs. 18F-FDG were 4.40 (95% CI − 0.7, 9.5) and 6.18 (95% CI 1.74, 10.61), respectively. Moderate to high heterogeneity was noted because of the variations in patient selection, interpretation criteria, and scanning procedures. This study revealed that [68Ga] FAPI- 46 outperforms [18F] FDG in cancer diagnosis, with higher sensitivity (0.96 vs. 0.73) and specificity (0.92 vs. 0.83). [Ga] FAPI- 46 improved tumor detection with higher SUVmax and TBR. While FDG had a higher LR +, its lower LR − highlighted more false negatives. Accordingly, [68Ga] FAPI- 46 exhibited superior accuracy and reliability than FDG in cancer diagnosis. PROSPERO CRD 42023472270.
  • Complications Rate and Hip Function After Revision of Infected Hip Arthroplasty with Bone Defects using Bone Allografts: A Systematic Review and Meta-Analysis
    Mahdieh Samei, Seyed Mohammad Javad Mortazavi, Mahdieh Sahebi, Mahla Daliri, Mohsen Dehghani, et al.
    Archives of Bone and Joint Surgery, 2025
    Objectives: We performed a systematic review and meta-analysis to evaluate complication rates and hip function following the revision of infected hip arthroplasty with bone defects using bone allografts. Methods: A comprehensive search of the PubMed, Web of Science, Embase, and Cochrane Library databases was conducted up to January 2024 to identify pre-post clinical trials. The primary outcomes assessed were the risk of reinfection, a critical concern for surgeons, and hip functional scores. The methodological quality of the included studies was also evaluated. A weighted mean difference (WMD) with a 95% confidence interval (CI) was used as the pooled estimate for clinical outcomes through random-effects meta-analysis, accounting for heterogeneity across studies. Results: Of the 2,189 records retrieved, 12 pre-post clinical trials (with fair to good quality) were included in the meta-analysis, involving a total of 342 participants. The pooled mean difference in Harris Hip Score (HHS) was 36.86 (95% CI: 29.58 to 44.13) post-surgery. In a subgroup analysis of studies employing structural grafts, the HHS increased by 36.99 (95% CI: 29.56 to 44.42). The overall reinfection rate was 6%. Subgroup analysis revealed that in studies utilizing morselized and structural allografts, the reinfection rates were 6% and 3%, respectively. The overall mean rate of aseptic loosening was 5%. Subgroup analysis showed that in studies using morselized grafts, the rate of aseptic loosening was 4%. The incidence of dislocation was 2% in the morselized group and 5% in the structural group. Conclusion: Revision of infected hip arthroplasty with bone defects using bone allografts may improve hip function. Interestingly, morselized allografts are often associated with higher rates of reinfection. Additionally, our findings suggest that structural allografts are associated with increased dislocation rates compared to morselized allografts. This difference may be attributed to the larger and more complex defects that necessitated the use of structural allografts rather than morselized grafts.
  • The clinical potentials of combining paclitaxel-based chemotherapy regimen with metformin in cancer treatment: A systematic review and Meta-analysis
    Behnam Omidi Sarajar, Nima Rastegar-Pouyani, Azadeh Rasouli, Fateme Nikbakht, Mahdieh Nezami Majd, Mohammad H. Ghahremani, Seyed Nasser Ostad, Emad Jafarzadeh, Mohsen Dehghani
    Translational Oncology, 2025
    • Combination of paclitaxel-based chemotherapy with metformin enhances overall survival (OS) in cancer patients. • Combination of paclitaxel-based chemotherapy with metformin enhances pathological complete response (pCR) in cancer patients. • Combination of paclitaxel-based chemotherapy with metformin has the potential to improve treatment effectiveness. • Combination of paclitaxel-based chemotherapy with metformin has the potential to minimize treatment-associated adverse events. Several clinical trials have shown that combining metformin with paclitaxel-based chemotherapy has a promising effect on various tumors but with inconsistent findings. We conducted a systematic review and meta-analysis to compare the effects of paclitaxel plus metformin versus paclitaxel-based chemotherapy alone in different organ neoplasms. A comprehensive literature search was performed in Scopus, PubMed, Web of Sciences, Embase and also Google scholar until December 2023 using MeSH keywords and all similar terms limited to randomized controlled trials (RCTs). The retrieved studies were assessed for methodological quality. Pooled standardize mean difference (SMD), odds ratio (OR) and 95 % confidence intervals (CI) of clinical outcomes were calculated using random-effects meta-analysis. Of 921 records, ultimately, 14 RCTs met the criteria for inclusion in the meta-analysis. Based on a meta-analysis findings, combination therapy of a paclitaxel-based regimen with metformin was found to be significantly associated with improved overall survival (OS) compared to the paclitaxel alone in various types of cancers (pooled SMD: 1.27; 95 % CI: 0.10, 2.43). Moreover, the metformin plus paclitaxel showed a borderline significant improvement in the pathological complete response (pCR) rate compared to the paclitaxel alone (Pooled OR: 1.74; 95 % CI: 0.96, 3.15). However, there was no significant improvement in the metformin plus paclitaxel group compared to the paclitaxel group for progression-free survival (PFS) and disease-free survival (DFS). The findings indicate that a combination of paclitaxel-based chemotherapy with metformin enhances OS and pCR in cancer patients. This combination therapy has the potential to improve treatment effectiveness and safety.
  • Efficacy and safety of premixed versus basal-bolus regimens as intensification of insulin therapy in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized clinical trials
    Mohsen Dehghani, Masoumeh Sadeghi, Farzaneh Barzkar, Mohammad Ebrahim Khamseh, Ashkan Torshizian, Hamid Reza Baradaran
    Journal of Diabetes Investigation, 2025
  • Comparing the effectiveness of two telemedicine counseling interventions on secondary tokophobia in single-child women: the study protocol of a pragmatic three-arm randomized controlled trial
    Maryam Ramezani, Mohsen Dehghani, Somaye Minaei Moghadam, Sedigheh Abdollahpour
    Journal of Psychosomatic Obstetrics and Gynecology, 2025
  • The Relationship between Female Genital Mutilation and Infertility: A systematic review and meta-analysis
    Narges S. Soltani, Farahnaz Heshmat, Mohsen Dehghani, Robab L. Roudsari, Mohadese B. Ghalibaf, Samira E. Zagami
    Sultan Qaboos University Medical Journal, 2025
  • Utilization of Rehabilitation Services by Disabled People under the Iranian Health Insurance Organization
    Samira Arabi, Mohammad Mahdi Nasehi, Zahra Shahali, Ali Shojaee, Mohsen Dehghani, Mehdi Rezaee, Hossein Ranjbaran, Parvaneh Keyhani, Rajabali Daroudi
    Medical Journal of the Islamic Republic of Iran, 2025
  • Clinical Outcomes and Complications Following Hip Fusion Conversion to Total Hip Arthroplasty: A Systematic Review and Meta-Analysis
    Mahla Daliri, Seyed Mohammad Hassan Moallem, Masoumeh Sadeghi, Mohsen Dehghani, Ali Parsa, Ali Moradi, Omid Shahpari, Mohammad H. Ebrahimzadeh
    Journal of Arthroplasty, 2024
  • Efficacy and safety of basal insulins in people with type 2 diabetes mellitus: a systematic review and network meta-analysis of randomized clinical trials
    Mohsen Dehghani, Masoumeh Sadeghi, Farzaneh Barzkar, Zohreh Maghsoomi, Leila Janani, Seyed Abbas Motevalian, Yoon K. Loke, Faramarz Ismail-Beigi, Hamid Reza Baradaran, Mohammad E. Khamseh
    Frontiers in Endocrinology, 2024
  • Prognostic value of CD44 expression in oral squamous cell carcinoma: A meta-analysis
    Majid Mirhashemi, Masoumeh Sadeghi, Narges Ghazi, Nasrollah Saghravanian, Mohsen Dehghani, Amin Aminian
    Annals of Diagnostic Pathology, 2023
  • A Systematic Review and Meta-Analysis of the Relationship between Receiving the Flu Vaccine with Acute Cerebrovascular Accident and Its Hospitalization in the Elderly
    Nilay Rezaei Tavabe, Soleiman Kheiri, Mohsen Dehghani, Abdollah Mohammadian-Hafshejani
    Biomed Research International, 2023
  • The Effect of Telenursing on Disease Outcomes in People with Type 2 Diabetes Mellitus: A Narrative Review
    Mina AkbariRad, Mohsen Dehghani, Masoumeh Sadeghi, Ashkan Torshizian, Nikoo Saeedi, Mehrdad Sarabi, Mahdieh Sahebi, Mohammad Taghi Shakeri
    Journal of Diabetes Research, 2023
  • Efficacy of Herbal Medicines on Lung Function in Asthma: a systematic review and meta-analysis of randomized controlled trials
    Alireza Derakhshan, Masoumeh Sadeghi, Amir-Mohammad-Hashem Asnaashari, Mohsen Dehghani, Roshanak Salari, Majid Khadem-Rezaiyan, Majid Mirsadraee, Shahin Saeidinejat, Shima Jalali, Shabnam Jalali
    Journal of Pharmacopuncture, 2023
  • National geographical pattern of COVID-19 hospitalization, case fatalities, and associated factors in patients covered by Iran Health Insurance Organization
    Soheila Damiri, Ali Shojaee, Mohsen Dehghani, Zahra Shahali, Sadrollah Abbasi, Rajabali Daroudi
    BMC Public Health, 2022
  • The effect of nanoparticles on pulmonary fibrosis: a systematic review and Meta-analysis of preclinical studies
    Rana Shahabi, Mohsen Dehghani, Seyed Ali Javad Moosavi, Bahareh Shahabi, Omid Poordakan, Masoumeh Sadeghi, Leila Aryan, Alireza Ghasempoor, Fatemeh Aghanasiri, Mojdeh Mohseni, Bita Mehravi
    Archives of Environmental and Occupational Health, 2022
  • Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis
    Tiberiu A. Pana, Mohsen Dehghani, Hamid Reza Baradaran, Samuel R. Neal, Adrian D. Wood, Chun Shing Kwok, Yoon K. Loke, Robert N. Luben, Mamas A. Mamas, Kay-Tee Khaw, Phyo Kyaw Myint
    European Journal of Epidemiology, 2021
  • Elevated Blood-Based Brain Biomarker Levels in Patients with Epileptic Seizures: A Systematic Review and Meta-analysis
    Leila Simani, Masoumeh Sadeghi, Fari Ryan, Mohsen Dehghani, Somayeh Niknazar
    ACS Chemical Neuroscience, 2020
  • Evaluation of targetable biomarkers for chimeric antigen receptor T-cell (CAR-T) in the treatment of pancreatic cancer: a systematic review and meta-analysis of preclinical studies : Pancreatic cancer is one of the lethal malignant tumours in the world. In this study, we investigated the CAR T-Cell therapy of pancreatic cancer
    Maryam Sahlolbei, Mohsen Dehghani, Behghat Kheiri yeghane azar, Somayeh Vafaei, G Roviello, Alberto D’Angelo, Zahra Madjd, Jafar Kiani
    International Reviews of Immunology, 2020
  • Association of antibiotics therapy during pregnancy with spontaneous miscarriage: a systematic review and meta-analysis
    Ara Omranipoor, Maryam Kashanian, Mohsen Dehghani, Masoumeh Sadeghi, Hamid Reza Baradaran
    Archives of Gynecology and Obstetrics, 2020
  • The Association of Food Intake and Physical Activity with Body Composition, Muscle Strength, and Muscle Function in Postmenopausal Women
    Mohammadreza Vafa, Behnaz Abiri, Mohsen Dehghani
    Methods in Molecular Biology, 2020
  • Effect of Vitamin D Supplementation on Muscle Strength, Muscle Function, and Body Composition in Vitamin D-Deficient Middle-Aged Women
    Behnaz Abiri, Mohsen Dehghani, Mohammadreza Vafa
    Methods in Molecular Biology, 2020
  • THE ROLE OF CELECOXIB IN GLIOBLASTOMA TREATMENT: A REVIEW OF LITERATURE
    F. Tavakolian, S. Sana Khezrnia, M. Dehghani, A. Mansouri
    World Cancer Research Journal, 2020
  • Efficacy of complete rings (MyoRing) in treatment of Keratoconus: a systematic review and meta-analysis
    Leila Janani, Kiarash Tanha, Fereshteh Najafi, Khosrow Jadidi, Farhad Nejat, Seyed Javad Hashemian, Mohsen Dehghani, Masoumeh Sadeghi
    International Ophthalmology, 2019
  • Association of sugar sweetened beverages consumption with non-alcoholic fatty liver disease: a systematic review and meta-analysis
    Farzaneh Asgari-Taee, Nahid Zerafati-Shoae, Mohsen Dehghani, Masoumeh Sadeghi, Hamid R. Baradaran, Shima Jazayeri
    European Journal of Nutrition, 2019
  • Association between tobacco smoking and opioid use: A meta-analysis
    Abdolhalim Rajabi, Mohsen Dehghani, Azadeh Shojaei, Mojtaba Farjam, Seyed Abbas Motevalian
    Addictive Behaviors, 2019
  • Modeling the burden of cardiovascular diseases in Iran from 2005 to 2025: The impact of demographic changes
    Iranian Journal of Public Health, 2017
  • Quality assessment of 30 various brands of bottled drinking waters in Iran
    D. Mohsen, N. Saeid, S. Hajer, N. Pyrasteh
    Environment Protection Engineering, 2016
  • Relationship between Epworth Sleepiness Scale and obstructive sleep apnea with road accidents
    Iran Occupational Health, 2015
  • Sleep habits and road traffic accident risk for Iranian occupational drivers
    Mohammad Hossein Ebrahimi, Masoumeh Sadeghi, Mohsen Dehghani, Khosro Sadegh Niiat
    International Journal of Occupational Medicine and Environmental Health, 2015
  • Effect of fluoride in drinking water on birth height and weight: An ecological study in Kerman Province, Zarand county, Iran
    Fluoride, 2015
  • Awareness of religious leaders' fatwa and willingness to donate organ
    International Journal of Organ Transplantation Medicine, 2015
  • Investigating happiness and its related factors in married women referred to health centers of shahroud city
    Zahra Sooky, Afsaneh Keramat, Khadijeh Sharifi, Mohsen Dehghani, Zahra Tagharrobi, Mahboubeh Taebi, Zohreh Sadat
    Iranian Red Crescent Medical Journal, 2014
  • Drinking water fluoride and child dental caries in Khartooran, Iran
    Fluoride, 2014
  • Quality of journal of obstetrics and gynecology in ISI and scopus databases based on indices of ranking journals
    Iranian Journal of Obstetrics Gynecology and Infertility, 2014
  • Comment on: Prevalence of diabetes in people aged >30 years: The results of screening program of Yazd province, Iran in 2012
    Journal of Research in Health Sciences, 2014
  • Hip circumference, height and risk of type 2 diabetes: Systematic review and meta-analysis
    M. Janghorbani, F. Momeni, M. Dehghani
    Obesity Reviews, 2012
  • Systematic Review and Meta-analysis of Insulin Therapy and Risk of Cancer
    Mohsen Janghorbani, Mohsen Dehghani, Mohammad Salehi-Marzijarani
    Hormones and Cancer, 2012

RECENT SCHOLAR PUBLICATIONS

  • Investigating the nutritional and mental health status in the suburbs of Northeast Iran: a register-based study
    M Andish, EM Farkhani, A Taghipoor, S Eslami, Z Amiri, N Khodadadi, ...
    BMC Public Health 26 (1), 322 , 2026
    2026
    Citations: 1
  • The Role of LTF , ENAM , and AMELX Gene Polymorphisms in Dental Caries Susceptibility: A Meta-Analysis
    D Shojaei, HS Mohammadipour, S Sekandari, M Dehghani, ...
    Current Genetic Medicine Reports 14 (1), 4 , 2026
    2026
  • Epidemiological pattern of death and causes of death in registered immigrants of Northeast Iran during the 2013–2023: a cross-sectional study
    S Eslami, EM Farkhani, M Sadeghi, M Andish, N Khodadadi, M Dehghani
    BMC Public Health , 2026
    2026
  • Hospital information systems evaluation criteria: a scoping review
    H Khorasani, S Damiri, S Abbasi, A Fathabadi, M Dehghani, M Sadeghi
    BMC Health Services Research 26, 184 , 2026
    2026
    Citations: 1
  • Comparing the effectiveness of two telemedicine counseling interventions on secondary tokophobia in single-child women: the study protocol of a pragmatic three-arm randomized …
    M Ramezani, M Dehghani, S Minaei Moghadam, S Abdollahpour
    Journal of Psychosomatic Obstetrics & Gynecology 46 (1), 2500928 , 2025
    2025
  • Clinical and functional outcomes of subacromial spacer implantation and superior capsular reconstruction for massive irreparable rotator cuff tears: a systematic review and …
    N Kalali, MH Ebrahimzadeh, M Dehghani, A Moradi, M Sahebi, N Jirofti
    BMC Musculoskeletal Disorders , 2025
    2025
    Citations: 1
  • Mesenchymal Stem Cell Transplantation for Osteogenesis Imperfecta Patients: A Systematic Review
    MM Khorasani, MH Ebrahimzadeh, M Dehghani, M Sharafoddin, ...
    Annals of the New York Academy of Sciences 1554 (1), 27-44 , 2025
    2025
    Citations: 1
  • Clinical outcomes of artificial meniscus scaffolds for partial meniscus injury: a systematic review and meta-analysis
    A Jahani, MH Ebrahimzadeh, M Dehghani, M Sharafoddin, A Moradi, ...
    Knee Surgery & Related Research 37 (1), 41 , 2025
    2025
    Citations: 2
  • The clinical potentials of combining paclitaxel-based chemotherapy regimen with metformin in cancer treatment: A systematic review and Meta-analysis
    BO Sarajar, N Rastegar-Pouyani, A Rasouli, F Nikbakht, MN Majd, ...
    Translational Oncology 59, 102438 , 2025
    2025
    Citations: 5
  • Revolutionizing cancer diagnosis and dose biodistribution: a meta-analysis of [68ga] FAPI-46 vs.[18f] FDG imaging
    S Abbasi, M Dehghani, S Khademi, R Irajirad, ZP Parizi, M Sahebi, ...
    Systematic Reviews 14 (1), 109 , 2025
    2025
    Citations: 8
  • The Relationship between Female Genital Mutilation and Infertility: A systematic review and meta-analysis
    NS Soltani, F Heshmat, M Dehghani, RL Roudsari, MB Ghalibaf, ...
    Sultan Qaboos University Medical Journal 25 (1), 310 , 2025
    2025
    Citations: 2
  • Efficacy and safety of premixed versus basal‐bolus regimens as intensification of insulin therapy in patients with type 2 diabetes mellitus: A systematic review and meta …
    M Dehghani, M Sadeghi, F Barzkar, ME Khamseh, A Torshizian, ...
    Journal of Diabetes Investigation 16 (5), 827-841 , 2025
    2025
    Citations: 3
  • Complications Rate and Hip Function After Revision of Infected Hip Arthroplasty with Bone Defects using Bone Allografts: A Systematic Review and Meta-Analysis
    M Samei, SMJ Mortazavi, M Sahebi, M Daliri, M Dehghani, RH Zadeh, ...
    Archives of Bone and Joint Surgery 13 (9), 537 , 2025
    2025
    Citations: 1
  • Utilization of Rehabilitation Services by Disabled People under the Iranian Health Insurance Organization
    RD Samira Arabi, Mohammad M Nasehi, Zahra Shahali, Ali Shojaee, Mohsen ...
    Medical Journal of The Islamic Republic of Iran (MJIRI) 39 (1) , 2025
    2025
  • Efficacy and safety of basal insulins in people with type 2 diabetes mellitus: a systematic review and network meta-analysis of randomized clinical trials
    M Dehghani, M Sadeghi, F Barzkar, Z Maghsoomi, L Janani, ...
    Frontiers in Endocrinology 15, 1286827 , 2024
    2024
    Citations: 5
  • Clinical outcomes and complications following hip fusion conversion to total hip arthroplasty: a systematic review and meta-analysis
    M Daliri, SMH Moallem, M Sadeghi, M Dehghani, A Parsa, A Moradi, ...
    The Journal of Arthroplasty 39 (1), 261-268. e36 , 2024
    2024
    Citations: 7
  • Prognostic value of CD44 expression in oral squamous cell carcinoma: A meta-analysis
    M Mirhashemi, M Sadeghi, N Ghazi, N Saghravanian, M Dehghani, ...
    Annals of Diagnostic Pathology 67, 152213 , 2023
    2023
    Citations: 28
  • Efficacy of herbal medicines on lung function in asthma: a systematic review and meta-analysis of randomized controlled trials
    A Derakhshan, M Sadeghi, M Dehghani, R Salari, M Khadem-Rezaiyan, ...
    Journal of pharmacopuncture 26 (2), 124 , 2023
    2023
    Citations: 12
  • The effect of telenursing on disease outcomes in people with type 2 diabetes mellitus: a narrative review
    M AkbariRad, M Dehghani, M Sadeghi, A Torshizian, N Saeedi, M Sarabi, ...
    Journal of diabetes research 2023 (1), 4729430 , 2023
    2023
    Citations: 25
  • A Systematic Review and Meta‐Analysis of the Relationship Between Receiving the Flu Vaccine With Acute Cerebrovascular Accident and Its Hospitalization in the Elderly
    NR Tavabe, S Kheiri, M Dehghani, A Mohammadian-Hafshejani
    BioMed Research International 2023 (1), 2606854 , 2023
    2023
    Citations: 19

MOST CITED SCHOLAR PUBLICATIONS

  • Modeling the burden of cardiovascular diseases in Iran from 2005 to 2025: the impact of demographic changes
    M Sadeghi, AA Haghdoost, A Bahrampour, M Dehghani
    Iranian journal of public health 46 (4), 506 , 2017
    2017
    Citations: 218
  • Comment on:" Prevalence of Diabetes in people aged> 30 years: The results of screening program of Yazd province, Iran in 2012"
    M Sadeghi, M Dehghani, AA Haghdoost
    Journal of Research in Health Sciences 14 (2), 167-168 , 2014
    2014
    Citations: 170
  • Systematic Review and Meta-analysis of Insulin Therapy and Risk of Cancer.
    M Janghorbani, M Dehghani, M Salehi-Marzijarani
    Hormones & cancer 3, 137-146 , 2012
    2012
    Citations: 121
  • Association of sugar sweetened beverages consumption with non-alcoholic fatty liver disease: a systematic review and meta-analysis
    F Asgari-Taee, N Zerafati-Shoae, M Dehghani, M Sadeghi, HR Baradaran, ...
    European journal of nutrition 58 (5), 1759-1769 , 2019
    2019
    Citations: 112
  • Association between tobacco smoking and opioid use: a meta-analysis
    A Rajabi, M Dehghani, A Shojaei, M Farjam, SA Motevalian
    Addictive behaviors 92, 225-235 , 2019
    2019
    Citations: 97
  • Hip circumference, height and risk of type 2 diabetes: systematic review and meta‐analysis
    M Janghorbani, F Momeni, M Dehghani
    Obesity Reviews 13 (12), 1172-1181 , 2012
    2012
    Citations: 93
  • Awareness of religious leaders’ fatwa and willingness to donate organ
    MA Aghaee, M Dehghani, M Sadeghi, E Khaleghi
    International journal of organ transplantation medicine 6 (4), 158 , 2015
    2015
    Citations: 64
  • SLEEP HABITS AND ROAD TRAFFIC ACCIDENT RISK FOR IRANIAN OCCUPATIONAL DRIVERS
    MH EBRAHIMI, M SADEGHI, M DEHGHANI, KS NIIAT
    Int J Occup Med Env Health 28 (2), 305-312 , 2015
    2015
    Citations: 60
  • Calcium intake, calcium supplementation and cardiovascular disease and mortality in the British population: EPIC-norfolk prospective cohort study and meta-analysis: TA Pana et al.
    TA Pana, M Dehghani, HR Baradaran, SR Neal, AD Wood, CS Kwok, ...
    European journal of epidemiology 36 (7), 669-683 , 2021
    2021
    Citations: 53
  • Effect of fluoride in drinking water on birth height and weight. An ecological study in Kerman province, Zarand county, Iran
    MAH Aghaei M, Derakhshani R, Raoof M, Dehghani M
    Fluoride 48 (2), 160-168 , 2015
    2015
    Citations: 40
  • Elevated blood-based brain biomarker levels in patients with epileptic seizures: a systematic review and meta-analysis
    L Simani, M Sadeghi, F Ryan, M Dehghani, S Niknazar
    ACS Chemical Neuroscience 11 (24), 4048-4059 , 2020
    2020
    Citations: 35
  • Association of antibiotics therapy during pregnancy with spontaneous miscarriage: a systematic review and meta-analysis
    A Omranipoor, M Kashanian, M Dehghani, M Sadeghi, HR Baradaran
    Archives of gynecology and obstetrics 302 (1), 5-22 , 2020
    2020
    Citations: 34
  • Investigating Happiness and its Related Factors in Married Women Referred to Health Centers of Shahroud City
    Z Sooky, A Keramat, K Sharifi, M Dehghani, Z Tagharrobi, M Taebi, ...
    Iran Red Crescent Med J 16 (9), 21-32 , 2014
    2014
    Citations: 30
  • Prognostic value of CD44 expression in oral squamous cell carcinoma: A meta-analysis
    M Mirhashemi, M Sadeghi, N Ghazi, N Saghravanian, M Dehghani, ...
    Annals of Diagnostic Pathology 67, 152213 , 2023
    2023
    Citations: 28
  • The effect of telenursing on disease outcomes in people with type 2 diabetes mellitus: a narrative review
    M AkbariRad, M Dehghani, M Sadeghi, A Torshizian, N Saeedi, M Sarabi, ...
    Journal of diabetes research 2023 (1), 4729430 , 2023
    2023
    Citations: 25
  • Hormonal and reproductive risk factors associated with breast cancer in Isfahan patients
    M Tazhibi, M Dehghani*, S Babazadeh, F Makkarian, M Tabatabaeian, ...
    J Edu Health Promot 3 (69), 106-111 , 2014
    2014
    Citations: 25
  • A Systematic Review and Meta‐Analysis of the Relationship Between Receiving the Flu Vaccine With Acute Cerebrovascular Accident and Its Hospitalization in the Elderly
    NR Tavabe, S Kheiri, M Dehghani, A Mohammadian-Hafshejani
    BioMed Research International 2023 (1), 2606854 , 2023
    2023
    Citations: 19
  • Efficacy of complete rings (MyoRing) in treatment of Keratoconus: a systematic review and meta-analysis
    L Janani, K Tanha, F Najafi, K Jadidi, F Nejat, SJ Hashemian, ...
    International Ophthalmology 39 (12), 2929-2946 , 2019
    2019
    Citations: 19
  • Effect of vitamin D supplement consumption on muscle strength, muscle function and body composition in vitamin D-deficient middle-aged women: a randomized clinical trial
    B Abiri, MR Vafa, M Dehghani, N Moslehi, J Sarrafzadeh
    Nutrition and food in health and disease 3 (3), 17-24 , 2016
    2016
    Citations: 18
  • Relationship between Epworth Sleepiness Scale and obstructive sleep apnea with road accidents.
    M Dehghani, KS Niat, MH Ebrahimi
    2015
    Citations: 14