Francisco Leonardo Torres-Leal

Scopus Publications

Fasting-mimicking diets as a strategy to reprogram tumor metabolism: a systematic review
Irislene Costa Pereira, Jorddam Almondes Martins, Dallyla Jennifer Morais de Sousa, Maria Shelda de Oliveira Neres, Rodrigo Soares Pereira Lima, et al.
European Journal of Nutrition, 2026
Behavioral standardization and validation of a new model of cancer-induced depression in sarcoma-bearing mice
Rayran Walter Ramos de Sousa, Ingredy Lopes dos Santos, Débora Caroline do Nascimento Rodrigues, Maria Luísa Lima Barreto do Nascimento, Micaely Lorrana Pereira Conceição, et al.
Physiology and Behavior, 2026
The Influence of Exercise on the Endocrine System: Impacts on Adolescent Growth and Development
Juliana Soares Severo, Rodrigo Soares Pereira Lima, Aureliano Machado de Oliveira, Thiago Sousa Reinaldo, Francisco Leonardo Torres-Leal, et al.
Advances in Experimental Medicine and Biology, 2026
Colorectal cancer therapy and nutrition: From ultra-processed consumption to metabolic reprogramming
Rodrigo Soares Pereira Lima, Jheniffer da Silva Sousa, Maria Shelda de Oliveira Neres, Dallyla Jennifer Morais de Sousa, Jorddam Almondes Martins, et al.
World Journal of Gastrointestinal Oncology, 2026
This narrative review examines the role of dietary patterns in colorectal cancer (CRC) development and management, with a focus on the diet-microbiome-metabolic reprogramming axis. CRC is one of the most prevalent and lethal malignancies worldwide, with pathogenesis shaped by genetic susceptibility, environmental exposures, and diet-related metabolic disturbances. High consumption of ultra-processed foods (UPFs), characterized by low fiber content and high levels of additives, has been associated with intestinal barrier dysfunction, dysbiosis, chronic inflammation, and oxidative stress, and a meta-analysis indicates that each 10% increase in UPF consumption corresponds to a 4% higher CRC risk. In contrast, metabolic dietary interventions, such as caloric restriction, fasting or fasting-mimicking diets, and ketogenic diets, have been primarily explored in preclinical models, demonstrating effects on tumor metabolism and inflammatory pathways. However, clinical evidence remains limited and heterogeneous, consisting mainly of small trials and observational studies with inconsistent protocols and variable adherence. This review critically synthesises current evidence by distinguishing between mechanistic insights and translational applicability. Well-designed clinical trials incorporating metabolic phenotyping and patient stratification are necessary to define the role of personalised nutrition as a potential adjunctive strategy in CRC prevention and treatment.
Caloric Restriction Enhances Chemotherapy Efficacy and Reshapes Stress Responses in Sarcoma
Jorddam Almondes Martins, Irislene Costa Pereira, Thiago Sousa Reinaldo, Dallyla Jennifer Morais de Sousa, Isabelle Vasconcelos Rodrigues, et al.
Cancers, 2026
Background: Oncological treatment remains a major clinical challenge. Despite therapeutic advances and the diversity of available approaches, many tumors continue to exhibit limited responsiveness to chemotherapy. In this context, nutrition has emerged as a promising complementary strategy to support cancer therapy. In particular, interventions based on nutritional deprivation have gained prominence due to their ability to modulate tumor metabolism, inducing alterations that may increase the sensitivity of cancer cells to conventional treatments. Accordingly, the present study aimed to evaluate the safety and efficacy of caloric restriction combined with chemotherapy in a Sarcoma-180 model, investigating its effects on immunological and hematological parameters, antioxidant activity, oxidative stress, and tumor and liver morphology, as well as DNA damage. Methods: Mice bearing Sarcoma-180 were randomly assigned to four groups: Ad Libitum (AL), Ad Libitum + Doxorubicin (ALDOX), Caloric Restriction (CR), and Caloric Restriction + Doxorubicin (CRDOX). Assessment included tumor weight and volume, food and caloric intake, hematotoxicity, lipid metabolism, oxidative stress and antioxidant markers, genotoxicity, morphological alterations in the tumor and liver, and overall survival. Results: The data obtained demonstrate that caloric restriction combined with doxorubicin is both safe and feasible, as it preserves body weight and does not induce metabolic disturbances. Importantly, this combined strategy produced a marked reduction in tumor volume and mass while also mitigating the hematotoxicity typically associated with doxorubicin. In peripheral blood, the regimen decreased chemotherapy-induced DNA damage, supporting a systemic protective effect. Consistently, the combination reduced oxidative stress markers (NOx and MDA) and enhanced antioxidant activity within the tumor. Histological analyses further confirmed these outcomes, showing tumor cell death with features compatible with apoptosis and reduced local invasion. Together, these data indicate that caloric restriction enhances the antitumor efficacy of doxorubicin while simultaneously improving treatment tolerance. Conclusions: This study demonstrates that caloric restriction, combined with doxorubicin, is safe, well-tolerated, and enhances the antitumor response in the Sarcoma-180 model.
Cellular toxicity of organotellurans: a systematic review of pre-clinical studies
Maria Luisa Lima Barreto do Nascimento, Isabela Ribeiro de Sá Guimarães Nolêto, Francisco Leonardo Torres-Leal, Felipe Cavalcanti Carneiro da Silva, João Marcelo de Castro e Sousa
Naunyn Schmiedeberg S Archives of Pharmacology, 2025
Role of physical exercise, vagal nerve stimulation, and vagotomy in inflammatory bowel disease
Alda Cassia Alves da Silva, Juliana Soares Severo, Brenda Lois Barros dos Santos, Heron Silva Soares, Jorddam Almondes Martins, et al.
World Journal of Gastroenterology, 2025
Inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis, represents the two predominant clinical entities within this spectrum of gastrointestinal disorders. Current evidence indicates that the etiology of IBD is multifactorial, involving a complex interplay between host genetic susceptibility and environmental determinants. In recent years, non-pharmacological strategies such as physical exercise and vagus nerve stimulation have gained increasing attention as adjunctive therapeutic approaches. Vagus nerve stimulation has emerged as a promising therapeutic modality, particularly in conditions characterized by autonomic dysfunction and diminished vagal tone. Conversely, vagotomy, by disrupting vagal control, abolishes parasympathetic reflexes and may potentiate inflammatory responses and exacerbate IBD symptomatology under stress conditions. Physical exercise has likewise been investigated as a non-pharmacological intervention in Crohn’s disease and ulcerative colitis. Although the precise mechanisms remain to be fully elucidated, accumulating evidence suggests that skeletal muscle contractions promote the secretion of myokines, with recognized anti-inflammatory properties. These myokines act on the intestinal microenvironment, conferring protection against malignant transformation and modulating the composition and function of the gut microbiota. In this review, we critically examine the interplay between physical exercise, vagus nerve stimulation, and vagotomy in the pathophysiology and management of IBD, with particular emphasis on their immunomodulatory and therapeutic potential.
Can Pembrolizumab or Nivolumab be efficiently used against colorectal cancers with defective mismatch repair and high index of microsatellite instability?
Glauto Tuquarre Melo do Nascimento, Irislene Costa Pereira, Kynnara Gabriella Feitosa de Oliveira, Álina Mara Carvalho Pedrosa Santos, Maria Luisa Lima Barreto do Nascimento, et al.
Medical Oncology, 2025
Development of a 24-Hour Movement Behavior Questionnaire: Reliability and Validity Testing in College Students From Low-Income Regions
Marcus Vinicius Nascimento-Ferreira, Kliver Antonio Marin, Lorrane Cristine Conceição da Silva, Alaiana Marinho Franco, Francisco Leonardo Torres-Leal, et al.
Sage Open, 2025
In this study, we aimed to develop and test the psychometric properties of an online 24-hr movement behavior questionnaire (24 hr-MBQ). We recruited a sample of 195 undergraduate students. We developed a questionnaire based on 19 items extracted from previously validated questionnaires. We conducted reliability and construct validity assessment by classical test theory and structural validity assessment using unsupervised machine learning. In the classic test, we identified seven factors where the explained variance was 66.80% in the exploratory factor analysis, with no item excluded. We identified three clusters using unsupervised machine learning and this structure was able to distinguish differences in physical activity (physically active vs. long sleeper), sedentary behavior (all cluster comparison), and sleep time duration (all cluster comparison). Our findings suggest that the online 24 hr-MBQ is a reliable and structured construct for assessing 24-hr movement behaviors in college students.
Supplementation Containing Bromelain on the Side Effects of Oncological Treatment: Systematic Review
Irislene Costa Pereira, Raquel Barros Passos, Camila de Meneses Caetano Viana, Isabele Frazão Mascarenhas, Glauto Tuquarre de Melo Nascimento, et al.
Journal of Medicinal Food, 2025
Systemic therapies for the treatment of cancer collaborate to reduce cancer progression and have been used for decades. However, despite the clinical benefits, its long-term use is associated with toxicity, promoting important side effects that can compromise the quality of life. Enzyme supplementation has been pointed out as a therapeutic potential in several diseases. Bromelain is an enzyme complex that regulates pathways associated with inflammation. This review aims to evaluate the use of bromelain-containing supplements to improve the side effects of cancer treatment. This systematic review was developed in PubMed, Web of Science, and Cochrane Library, using the terms: Cancer AND Bromelain. 239 studies were retrieved, and only three met our objective. In general, it was possible to observe that supplementation was able to reduce side effects of adjuvant hormone therapy and chemotherapy, such as mucosal dryness, arthralgia, and peripheral neuropathy induced by chemotherapy.
Bromelain and liver health: A comprehensive systematic review of preclinical studies
Irislene Costa Pereira, Álina Mara Carvalho Pedrosa-Santos, Jorddam Almondes Martins, Athanara Alves de Sousa, Taline Alves Nobre, et al.
Clinical Nutrition Espen, 2025
Physical Exercise as a Therapeutic Approach in Gastrointestinal Diseases
Juliana Soares Severo, Alda Cássia Alves da Silva, Brenda Lois Barros dos Santos, Thiago Sousa Reinaldo, Aureliano Machado de Oliveira, et al.
Journal of Clinical Medicine, 2025
Physical Exercise Alleviates Oxidative Stress and Autonomic Dysregulation in a Rat Model of Inflammatory Bowel Disease
Brenda Lois Barros dos Santos, Alda Cássia Alves da Silva, Juliana Soares Severo, Bruno de Sousa Barbosa, Maisa Campêlo de Sousa, et al.
Antioxidants, 2025
Bromelain as a natural anti-inflammatory drug: a systematic review
Taline Alves Nobre, Athanara Alves de Sousa, Irislene Costa Pereira, Álina Mara Carvalho Pedrosa-Santos, Luana de Oliveira Lopes, et al.
Natural Product Research, 2025
Buthionine sulfoximine acts synergistically with doxorubicin as a sensitizer molecule on different tumor cell lines
Joedna Cavalcante Pereira, Rayran Walter Ramos de Sousa, Micaely Lorrana Pereira Conceição, Maria Luísa Lima Barreto do Nascimento, Ana Tárcila Alves de Almeida, et al.
Journal of Toxicology and Environmental Health Part A Current Issues, 2025
Brain Perception of Different Oils on Appetite Regulation: An Anorectic Gene Expression Pattern in the Hypothalamus Dependent on the Vagus Nerve
Gele de Carvalho Araújo Lopes, Brenda Caroline Rodrigues Miranda, João Orlando Piauilino Ferreira Lima, Jorddam Almondes Martins, Athanara Alves de Sousa, et al.
Nutrients, 2024
Dietary restriction and hepatic cancer: Systematic review and meta-analysis of animal studies
Dallyla Jennifer Morais de Sousa, Kynnara Gabriella Feitosa de Oliveira, Irislene Costa Pereira, Glauto Tuquarre Melo do Nascimento, Clenio Oliveira Barrense, et al.
Critical Reviews in Oncology Hematology, 2024
Editorial: Exercise physiology and gastrointestinal disorders
Moisés Tolentino Bento da Silva, Daniel Moreira-Gonçalves, Francisco Leonardo Torres-Leal, Arménio Aguiar dos Santos
Frontiers in Sports and Active Living, 2024
Treadmill Exercise Reverses the Adverse Effects of Intermittent Fasting on Behavior and Cortical Spreading Depression in Young Rats
Amanda Ferraz Braz, Maria Luísa Figueira de Oliveira, Dominique Hellen Silva da Costa, Francisco Leonardo Torres-Leal, Rubem Carlos Araújo Guedes
Brain Sciences, 2023
Physical exercise alleviates oxidative stress in brown adipose tissue and causes changes in body composition and nutritional behavior in rats with polycystic ovary syndrome
Wenna Lúcia Lima Santos, Clailson da Silva Pinheiro, Raisa de Oliveira Santos, Alda Cassia Alves da Silva, Juliana Soares Severo, et al.
Life Sciences, 2023
Consumption and supplementation of vitamin E in breast cancer risk, treatment, and outcomes: A systematic review with meta-analysis
Victor Alves de Oliveira, Iara Katrynne Fonseca Oliveira, Irislene Costa Pereira, Layza Karyne Farias Mendes, Felipe Cavalcanti Carneiro da Silva, et al.
Clinical Nutrition Espen, 2023
Chemopreventive and anti-tumor potential of vitamin E in preclinical breast cancer studies: A systematic review
Maria do Perpetuo Socorro de Sousa Coelho, Irislene Costa Pereira, Kynnara Gabriella Feitosa de Oliveira, Iara Katryne Fonseca Oliveira, Márcia dos Santos Rizzo, et al.
Clinical Nutrition Espen, 2023
RELATIONSHIP BETWEEN SELENIUM NUTRITIONAL STATUS AND MARKERS OF LOW-GRADE CHRONIC INFLAMMATION IN OBESE WOMEN
Larissa Cristina Fontenelle, Mickael de Paiva Sousa, Loanne Rocha dos Santos, Bruna Emanuele Pereira Cardoso, Thayanne Gabryelle Visgueira de Sousa, et al.
Biological Trace Element Research, 2023
Reliability and Validity Estimate of the Pro-Inflammatory/Anti-Inflammatory Food Intake Score in South American Pediatric Population: SAYCARE Study
Lívia Gabriele Azevedo-Garcia, Francisco Leonardo Torres-Leal, Juan Carlos Aristizabal, Gabriela Berg, Heráclito B. Carvalho, et al.
International Journal of Environmental Research and Public Health, 2023
Antimalarials and macrolides: a review of off-label pharmacotherapies during the first wave of the SARS-CoV-2 pandemic
Paulo Michel Pinheiro Ferreira, Rayran Walter Ramos de Sousa, Dalton Dittz, João Marcelo de Castro e Sousa, Francisco Leonardo Torres-Leal, et al.
Brazilian Journal of Pharmaceutical Sciences, 2023
α-tocopherol as a selective modulator of toxicogenic damage induced by antineoplastic agents cyclophosphamide and doxorubicin
Victor Alves de Oliveira, Andressa Naiane Rodrigues Monteiro Fernandes, Lauana Maria dos Santos Leal, Paloma Alves Ferreira Lima, Ana Rafaela Silva Pereira, et al.
Journal of Toxicology and Environmental Health Part A Current Issues, 2023
Cellular reprogramming, chemoresistance, and dietary interventions in breast cancer
Irislene Costa Pereira, Isabele Frazão Mascarenhas, Vinícius Cooper Capetini, Paulo Michel Pinheiro Ferreira, Marcelo Macedo Rogero, et al.
Critical Reviews in Oncology Hematology, 2022
Improvement of 2,2′-Azobis(2-Methylpropionamidine) Dihydrochloride-Induced Hepatic Redox Imbalance in Swiss Mice and HepG2 Cells by Rutin
Paula Alexandre de Freitas, Keciany Alves de Oliveira, Laryssa Alves Magalhães, Regina de Jesus das Neves, Carla Soraya Costa Maia, et al.
Journal of Medicinal Food, 2022
Evaluation of the Validity of a Food Frequency Questionnaire and 24-Hour Dietary Recall to Assess Dietary Iron Intake in Children and Adolescents from the South American Youth/Child Cardiovascular and Environmental Study
Tatiana Sadalla Collese, Augusto César F. De Moraes, Tara Rendo-Urteaga, Laura I. Gonzalez-Zapata, Diego Alejandro Gaitán Charry, et al.
Journal of the Academy of Nutrition and Dietetics, 2022
Probiotics in sports and physical exercise
Juliana Soares Severo, Alda Cássia Alves da Silva, Irislene Costa Pereira, Francisco Leonardo Torres-Leal, Moisés Tolentino Bento da Silva
Probiotics for Human Nutrition in Health and Disease, 2022
Reliability and validity of the dutch eating behavior questionnaire in an online format for university students from low-income regions in a pandemic context: A 24 hour MESYN study
Millena Vaz de Carvalho, Antonio Gibran de Almeida Cardoso, Shirley Cunha Feuerstein, Rosana Rodrigues de Sousa, Tatiana Sadalla Collese, et al.
Frontiers in Epidemiology, 2022
24 h movement behavior and metabolic syndrome study protocol: A prospective cohort study on lifestyle and risk of developing metabolic syndrome in undergraduate students from low-income regions during a pandemic
Marcus Vinicius Nascimento-Ferreira, Kliver Antonio Marin, Ruhena Kelber Abrão Ferreira, Luiz Fernando Oliveira, Ana Caroline Bandeira, et al.
Frontiers in Epidemiology, 2022
Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
Mar Quiñones, René Hernández-Bautista, Daniel Beiroa, Violeta Heras, Francisco L. Torres-Leal, et al.
Redox Biology, 2021
Acute strength exercise decreases satiety by modifying blood cytokines levels in physically active men
Thamires Mendonça de Carvalho, Juliana Soares Severo, Felipe Giovanni de Sousa e Silva Santos, Ana Karolina Martins Cavalcante, Alexandre Havt, et al.
Motriz Revista De Educacao Fisica, 2021
Sampling and processing blood samples within the South American Youth/Child cARdiovascular and Environmental (SAYCARE) Study
Graciela López, Raphael Assali Serruya, Magalí Barchuk, Diego Gaitan-Charry, Francisco Leonardo Torres-Leal, et al.
Scientific Reports, 2020
Food consumption of branched chain amino acids and insulin resistance: A systematic review of observational studies in humans
Eduardo Emanuel Sátiro Vieira, Irislene Costa Pereira, Amanda Ferraz Braz, Marcus Vinicius Nascimento-Ferreira, Lucillia Rabelo de Oliveira Torres, et al.
Clinical Nutrition Espen, 2020
Oral Pharmacological Activation of Hypothalamic Guanylate Cyclase 2C Receptor Stimulates Brown Fat Thermogenesis to Reduce Body Weight
Cintia Folgueira, Francisco Leonardo Torres-Leal, Daniel Beiroa, Verónica Pena-León, Natália Da Silva Lima, et al.
Neuroendocrinology, 2020
Hypoglycaemic effect of resveratrol in streptozotocin-induced diabetic rats is impaired when supplemented in association with leucine
Liohanna Silva Pires D´Avila, Keciane Alves de Oliveira, Ewerton Sousa de Abreu, Renata Prado Vasconcelos, Jessica de Freitas Nascimento, et al.
International Journal of Food Sciences and Nutrition, 2020
Modulation and Consequences of Sleep Duration in Child Obesity
Marcus Vinicius Nascimento-Ferreira, Augusto César Ferreira De Moraes, Francisco Leonardo Torres-Leal, Heráclito Barbosa Carvalho
Neurological Modulation of Sleep Mechanisms and Function of Sleep Health, 2020
Reliability and validity of an FFQ for South American children and adolescents from the SAYCARE study
Tara Rendo-Urteaga, Luisa Saravia, Tatiana Sadalla Collese, Julia María Monsalve-Alvarez, Laura Inés González-Zapata, et al.
Public Health Nutrition, 2020
Influence of the physical exercise on decrease in the gastric emptying and alter appetite and food behavior in rats dexamethasone-treatment
Lúcia Castro Santos de Oliveira, Pedro Victor Nogueira Telles, Jessica Fernanda Reis e Sousa, Ana Karolina Martins Cavalcante, Deysi Viviana Tenazoa Wong, et al.
Physiology and Behavior, 2019
Is self-reported physical fitness useful for estimating fitness levels in children and adolescents? A reliability and validity study
Augusto César Ferreira De Moraes, Regina Célia Vilanova-Campelo, Francisco Leonardo Torres-Leal, Heráclito Barbosa Carvalho
Medicina Lithuania, 2019
Leptin and adiposity as mediators on the association between early puberty and several biomarkers in European adolescents: The HELENA Study
Tara Rendo-Urteaga, Augusto César Ferreira de Moraes, Francisco Leonardo Torres-Leal, Yannis Manios, Frederic Gottand, et al.
Journal of Pediatric Endocrinology and Metabolism, 2018
Design and Objectives of the South American Youth/Child Cardiovascular and Environmental (SAYCARE) Study
Heráclito Barbosa Carvalho, Luis Alberto Moreno, Andrew Mello Silva, Gabriela Berg, Alejandro Estrada‐Restrepo, et al.
Obesity, 2018
Is the Measurement of Blood Pressure by Automatic Monitor in the South American Pediatric Population Accurate? SAYCARE Study
Keisyanne Araújo‐Moura, Augusto César Ferreira De Moraes, Elsie C.O. Forkert, Gabriela Berg, Gabriel Grizzo Cucato, et al.
Obesity, 2018
The lipid accumulation product is a powerful tool to predict metabolic syndrome in undiagnosed Brazilian adults
Marcus Vinicius Nascimento-Ferreira, Tara Rendo-Urteaga, Regina Célia Vilanova-Campelo, Heráclito Barbosa Carvalho, Germano da Paz Oliveira, et al.
Clinical Nutrition, 2017
ACE-modulated adiposity is related to higher energy expenditure and independent of lipolysis and glucose incorporation into lipids in adipocytes
Miriam Helena Fonseca-Alaniz, Talita Sayuri Higa, Tarcila Beatriz Ferraz-de-Campos, Julie Takada, Francisco Leonardo Torres-Leal, et al.
Physiological Genomics, 2017
Reply-Letter to the Editor-The lipid accumulation product is a powerful tool to predict metabolic syndrome in undiagnosed Brazilian adults
Marcus Vinicius Nascimento-Ferreira, Tara Rendo-Urteaga, Regina Célia Vilanova-Campelo, Heráclito Barbosa Carvalho, Germano da Paz Oliveira, et al.
Clinical Nutrition, 2017
Cross-sectional, school-based study of 14–19 year olds showed that raised blood pressure was associated with obesity and abdominal obesity
Marcus Vinícius Nascimento‐Ferreira, Augusto César Ferreira De Moraes, Tara Rendo‐Urteaga, Elsie Costa de Oliveira Forkert, Tatiana Sadalla Collese, et al.
Acta Paediatrica International Journal of Paediatrics, 2017
Thyroid Function in Human Obesity: Underlying Mechanisms
L. Fontenelle, M. Feitosa, J. Severo, T. Freitas, J. Morais, et al.
Hormone and Metabolic Research, 2016
Pequi (Caryocar brasiliense Camb.) almond oil attenuates carbon tetrachloride-induced acute hepatic injury in rats: Antioxidant and anti-inflammatory effects
Lucillia R. de O. Torres, Fernanda C. de Santana, Francisco L. Torres-Leal, Illana L.P. de Melo, Luciana T. Yoshime, et al.
Food and Chemical Toxicology, 2016
Magnesium Status and Its Relationship with C-Reactive Protein in Obese Women
Ana Raquel Soares de Oliveira, Kyria Jayanne Clímaco Cruz, Jennifer Beatriz Silva Morais, Juliana Soares Severo, Taynáh Emannuelle Coelho de Freitas, et al.
Biological Trace Element Research, 2015
Neonatal streptozotocin-induced diabetes in mothers promotes metabolic programming of adipose tissue in male rat offspring
Ariclécio C. Oliveira, Sandra Andreotti, Patricia Chimin, Rogério A.L. Sertié, Talita da S.M. Farias, et al.
Life Sciences, 2015
Prevalence of cardiovascular risk factors, the association with socioeconomic variables in adolescents from Low-Income region
Nutricion Hospitalaria, 2015
Pinealectomy interferes with the circadian clock genes expression in white adipose tissue
Talita da Silva Mendes de Farias, Ariclécio Cunha de Oliveira, Sandra Andreotti, Fernanda Gaspar do Amaral, Patrícia Chimin, et al.
Journal of Pineal Research, 2015
L-leucine supplementation worsens the adiposity of already obese rats by promoting a hypothalamic pattern of gene expression that favors fat accumulation
Thais Zampieri, Francisco Torres-Leal, Amanda Campaña, Fabio Lima, Jose Donato
Nutrients, 2014
Influence of magnesium on insulin resistance in obese women
Kyria Jayanne Clímaco Cruz, Ana Raquel Soares de Oliveira, Denise Pereira Pinto, Jennifer Beatriz Silva Morais, Fabiana da Silva Lima, et al.
Biological Trace Element Research, 2014
Chronic glucocorticoid treatment enhances lipogenic activity in visceral adipocytes of male Wistar rats
P. Chimin, T. da S. M. Farias, F. L. Torres‐Leal, A. Bolsoni‐Lopes, A. B. Campaña, et al.
Acta Physiologica, 2014
Palmitoleic acid (n-7) increases white adipocytes GLUT4 content and glucose uptake in association with AMPK activation
Andressa Bolsoni-Lopes, William T Festuccia, Patricia Chimin, Talita SM Farias, Francisco L Torres-Leal, et al.
Lipids in Health and Disease, 2014
Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner
Andressa Bolsoni-Lopes, William T. Festuccia, Talita S. M. Farias, Patricia Chimin, Francisco L. Torres-Leal, et al.
American Journal of Physiology Endocrinology and Metabolism, 2013
Maternal postnatal high-fat diet, rather than gestational diet, affects morphology and mTOR pathway in skeletal muscle of weaning rat
Lucas C. Pantaleão, Gabriela F.R. Teodoro, Francisco L. Torres-Leal, Daiana Vianna, Tatyana D. de Paula, et al.
Journal of Nutritional Biochemistry, 2013
Nutrient-adjusted high-fat diet is associated with absence of periepididymal adipose tissue inflammation: Is there a link with adequate micronutrient levels?
Monica Yamada, Marina Maintinguer Norde, Maria C. Borges, Tatiane Mieko de Meneses Fujii, Patrícia Silva Jacob, et al.
International Journal for Vitamin and Nutrition Research, 2013
Metabolic disorders and adipose tissue insulin responsiveness in neonatally STZ-induced diabetic rats are improved by long-term melatonin treatment
Ariclécio C. de Oliveira, Sandra Andreotti, Talita da S.M. Farias, Francisco L. Torres-Leal, André R.G. de Proença, et al.
Endocrinology, 2012
Long-term leucine supplementation reduces fat mass gain without changing body protein status of aging rats
Daiana Vianna, Gabriela Fulin Teodoro Resende, Francisco Leonardo Torres-Leal, Lucas Carminatti Pantaleão, Jose Donato, et al.
Nutrition, 2012
Leucine supplementation improves adiponectin and total cholesterol concentrations despite the lack of changes in adiposity or glucose homeostasis in rats previously exposed to a high-fat diet
Francisco L Torres-Leal, Miriam H Fonseca-Alaniz, Gabriela FR Teodoro, Mariana D de Capitani, Daiana Vianna, et al.
Nutrition and Metabolism, 2011
The role of inflamed adipose tissue in the insulin resistance
Francisco L. Torres‐Leal, Miriam H. Fonseca‐Alaniz, Marcelo M. Rogero, Julio Tirapegui
Cell Biochemistry and Function, 2010
Protein synthesis regulation by leucine
Daiana Vianna, Gabriela Fullin Resende Teodoro, Francisco Leonardo Torres-Leal, Julio Tirapegui
Brazilian Journal of Pharmaceutical Sciences, 2010
Effects of administering testosterone undecanoate in rats subjected to physical exercise: Effects on the estrous cycle, motor behavior and morphology of the liver and kidney
Moisés Tolentino Bento-Silva, Maria do Carmo de Carvalho e Martins, Francisco Leonardo Torres-Leal, Talvany Luiz Barros, Ingrid Lara do Nascimento Ferreira de Carvalho, et al.
Brazilian Journal of Pharmaceutical Sciences, 2010
The effect of physical exercise and caloric restriction on the components of metabolic syndrome
Francisco Leonardo Torres-Leal, Mariana Dutilh de Capitani, Julio Tirapegui
Brazilian Journal of Pharmaceutical Sciences, 2009
Considerations on the role of creatine on physical performance
Francisco Leonardo Torres-Leal, Dilina Do Nascimento Marreiro
Revista Brasileira De Cineantropometria E Desempenho Humano, 2008

Francisco Leonardo Torres-Leal

RESEARCH, TEACHING, or OTHER INTERESTS

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

MOST CITED SCHOLAR PUBLICATIONS