Jordi Minguillon

@rdgroups.ciemat.es

Senior researcher - CIEMAT/IIS-FJD Advanced Therapies Mixed Unit
CIEMAT

RESEARCH, TEACHING, or OTHER INTERESTS

Oncology, Immunology, Biochemistry, Genetics and Molecular Biology, Pediatrics, Perinatology and Child Health
1239

Scholar Citations

14

Scholar h-index

19

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Outcomes of two distinct T-cell depletion strategies in haploidentical vs unrelated donor pediatric HSCT: A single-center retrospective analysis
    L Sisinni, O León-Triana, MF Artazcoz, M Guariento, IFR de Asua, ...
    Leukemia Research, 108150 , 2025
    2025
  • Lentiviral-mediated panErbB CAR-T cell therapy against head and neck squamous cell carcinomas for patients with Fanconi anemia
    A López, D Charbonnier, P Vela, B Díez, P Río, R Sánchez, O Alberquilla, ...
    Molecular Therapy Oncology 33 (4) , 2025
    2025
    Citations: 1
  • Torque teno virus in pediatric CAR-T recipients
    Y Mozo, C del Pino, M Martín-Lunas, B González, V Galán, ...
    Blood 146, 5937 , 2025
    2025
  • Opening of a phase Ib/II study to investigate the safety and efficacy of Afatinib in patients with Fanconi anemia and unresectable locally advanced or metastatic head and neck …
    G Anguera, O Gallego, M Llobet, N Berga, ME Moreno-Martinez, X Leon, ...
    BMC cancer 25 (1), 1374 , 2025
    2025
    Citations: 2
  • CD19 CAR-T cell therapy in a pediatric patient with MDA5+ dermatomyositis and rapidly progressive interstitial lung disease
    A París-Muñoz, RM Alcobendas-Rueda, C Verdú-Sánchez, C Udaondo, ...
    Med 6 (8) , 2025
    2025
    Citations: 26
  • Tandem CD19/CD22 CAR T-cells as potential therapy for children and young adults with high-risk r/r B-ALL
    B González-Martínez, V Galán-Gómez, A Navarro-Zapata, ...
    Ebiomedicine 118 , 2025
    2025
    Citations: 6
  • CAR-T cells targeting CCR9 and CD1a for the treatment of T cell acute lymphoblastic leukemia
    N Tirado, K Fidyt, MJ Mansilla, A Garcia-Perez, A Martinez-Moreno, ...
    Journal of Hematology & Oncology 18 (1), 69 , 2025
    2025
    Citations: 10
  • Siltuximab for the treatment of early complications after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia in children, adolescents, and young adults
    V Galán-Gómez, B González-Martínez, A Alonso-Saladrigues, S Rives, ...
    Experimental hematology & oncology 14 (1), 49 , 2025
    2025
    Citations: 7
  • Prognostic significance of mutation type and chromosome fragility in Fanconi anemia
    MJ Ramírez, R Pujol, J Minguillón, M Bogliolo, I Persico, D Cavero, ...
    American journal of hematology 100 (2), 272-284 , 2025
    2025
    Citations: 14
  • Prognostic significance of mutation type and chromosome fragility in Fanconi anemia
    MJ Ramírez de Haro, R Pujol, J Minguillón, M Bogliolo, I Persico, ...
    Wiley , 2025
    2025
  • Challenges in the preclinical design and assessment of CAR-T cells
    H Mirzaei, J Sivalingam, J Minguillón, C Tomuleasa, R Tomai, ...
    2025
  • Targeting protein-protein interactions in drug discovery: Modulators approved or in clinical trials for cancer treatment
    C Camps-Fajol, D Cavero, J Minguillón, J Surrallés
    Pharmacological research 211, 107544 , 2025
    2025
    Citations: 33
  • Newer generations of multi-target CAR and STAb-T immunotherapeutics: NEXT CART Consortium as a cooperative effort to overcome current limitations
    B Martín-Antonio, B Blanco, Á González-Murillo, L Hidalgo, J Minguillón, ...
    Frontiers in immunology 15, 1386856 , 2024
    2024
    Citations: 13
  • DNA repair in cancer therapeutics: developing a specific inhibitor for tumors and targeted therapies to treat solid tumors in rare diseases
    DC Moreno
    Universitat Autònoma de Barcelona , 2024
    2024
  • DNA repair in cancer therapeutics: developing a specific inhibitor for tumors and targeted therapies to treat solid tumors in rare diseases
    D Cavero Moreno
    2024
  • Breaking Barriers in B-Acute Lymphoblastic Leukemia Treatment: Experience of a Tertiary Hospital with the Use of a Tandem Dual CAR-T 19/22 in Pediatric & AYA Patients
    B González-Martínez, V Galán-Gómez, JM Pedreno, A Navarro-Zapata, ...
    Blood 142, 6886 , 2023
    2023
  • TURNING NKG2D CAR-T THERAPY INTO AN IMPROVED IL18 TRUCK AS A TREATMENT FOR PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS
    L Clares-Villa, L Pertinez, A Navarro-Zapata, C Mestre-Duran, ...
    HUMAN GENE THERAPY 34 (21-22), A16-A16 , 2023
    2023
    Citations: 1
  • OPTIMIZING MULTITARGET APPROACH IN THE PEDIATRIC PATIENT: NEW PERSPECTIVES OF DUAL CD19/CD22 CAR-T
    V Galan-Gomez, B Gonzalez Martinez, I Mirones Aguilar, ...
    BONE MARROW TRANSPLANTATION 58 (SUPP 1), 198-199 , 2023
    2023
  • Immunotherapy: FAMILIAL CD45RA DEPLETED T CELLS TO TREAT SEVERE REFRACTORY INFECTIONS IN IMMUNOCOMPROMISED PATIENTS
    K Al-Akioui-Sanz, C Ferreras, A Martin-Quirós, M Menéndez-Ribes, ...
    Cytotherapy 25 (6), S211 , 2023
    2023
  • Donor selection for adoptive cell therapy with CD45RA− memory T cells for patients with coronavirus disease 2019, and dexamethasone and interleukin-15 effects on the phenotype …
    K Al-Akioui-Sanz, B Pascual-Miguel, M Díaz-Almirón, C Mestre-Durán, ...
    Cytotherapy 25 (3), 330-340 , 2023
    2023
    Citations: 6

MOST CITED SCHOLAR PUBLICATIONS

  • Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia
    M Bogliolo, B Schuster, C Stoepker, B Derkunt, Y Su, A Raams, JP Trujillo, ...
    The American Journal of Human Genetics 92 (5), 800-806 , 2013
    2013
    Citations: 404
  • Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5
    M Buxadé, G Lunazzi, J Minguillón, S Iborra, R Berga-Bolaños, M Del Val, ...
    Journal of Experimental Medicine 209 (2), 379-393 , 2012
    2012
    Citations: 195
  • Regulation of the hypertonic stress response and other cellular functions by the Rel-like transcription factor NFAT5
    J Aramburu, K Drews-Elger, A Estrada-Gelonch, J Minguillón, ...
    Biochemical pharmacology 72 (11), 1597-1604 , 2006
    2006
    Citations: 176
  • Analysis of the transcriptional activity of endogenous NFAT5 in primary cells using transgenic NFAT-luciferase reporter mice
    B Morancho, J Minguillón, JD Molkentin, C López-Rodríguez, J Aramburu
    BMC molecular biology 9 (1), 13 , 2008
    2008
    Citations: 58
  • Concentrations of cyclosporin A and FK506 that inhibit IL-2 induction in human T cells do not affect TGF-β1 biosynthesis, whereas higher doses of cyclosporin A trigger …
    J Minguillon, B Morancho, SJ Kim, M Lopez-Botet, J Aramburu
    Journal of leukocyte biology 77 (5), 748-758 , 2005
    2005
    Citations: 53
  • Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1
    G Hernández, MJ Ramírez, J Minguillón, P Quiles, G Ruiz de Garibay, ...
    Nature communications 9 (1), 967 , 2018
    2018
    Citations: 50
  • Gefitinib and afatinib show potential efficacy for Fanconi anemia–related head and neck cancer
    H Montanuy, Á Martínez-Barriocanal, J Antonio Casado, L Rovirosa, ...
    Clinical Cancer Research 26 (12), 3044-3057 , 2020
    2020
    Citations: 34
  • Targeting protein-protein interactions in drug discovery: Modulators approved or in clinical trials for cancer treatment
    C Camps-Fajol, D Cavero, J Minguillón, J Surrallés
    Pharmacological research 211, 107544 , 2025
    2025
    Citations: 33
  • Natural gene therapy by reverse mosaicism leads to improved hematology in Fanconi anemia patients
    MJ Ramírez, R Pujol, JP Trujillo‐Quintero, J Minguillon, M Bogliolo, P Rio, ...
    American Journal of Hematology 96 (8), 989-999 , 2021
    2021
    Citations: 28
  • CD19 CAR-T cell therapy in a pediatric patient with MDA5+ dermatomyositis and rapidly progressive interstitial lung disease
    A París-Muñoz, RM Alcobendas-Rueda, C Verdú-Sánchez, C Udaondo, ...
    Med 6 (8) , 2025
    2025
    Citations: 26
  • Chromosome fragility in the buccal epithelium in patients with Fanconi anemia
    MJ Ramírez, J Minguillón, S Loveless, K Lake, E Carrasco, N Stjepanovic, ...
    Cancer Letters 472, 1-7 , 2020
    2020
    Citations: 25
  • CIBERER: Spanish national network for research on rare diseases: A highly productive collaborative initiative
    J Luque, I Mendes, B Gomez, B Morte, M López de Heredia, E Herreras, ...
    Clinical genetics 101 (5-6), 481-493 , 2022
    2022
    Citations: 24
  • Epigenetic alterations in Fanconi anaemia: role in pathophysiology and therapeutic potential
    H Belo, G Silva, BA Cardoso, B Porto, J Minguillon, J Barbot, J Coutinho, ...
    PloS one 10 (10), e0139740 , 2015
    2015
    Citations: 16
  • Prognostic significance of mutation type and chromosome fragility in Fanconi anemia
    MJ Ramírez, R Pujol, J Minguillón, M Bogliolo, I Persico, D Cavero, ...
    American journal of hematology 100 (2), 272-284 , 2025
    2025
    Citations: 14
  • Newer generations of multi-target CAR and STAb-T immunotherapeutics: NEXT CART Consortium as a cooperative effort to overcome current limitations
    B Martín-Antonio, B Blanco, Á González-Murillo, L Hidalgo, J Minguillón, ...
    Frontiers in immunology 15, 1386856 , 2024
    2024
    Citations: 13
  • Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia
    R Errazquin, A Page, A Suñol, C Segrelles, E Carrasco, J Peral, ...
    Oral Oncology 134, 106184 , 2022
    2022
    Citations: 11
  • Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia
    JA Casado, A Valeri, R Sanchez-Domínguez, P Vela, A López, S Navarro, ...
    The Journal of Clinical Investigation 132 (15) , 2022
    2022
    Citations: 11
  • CAR-T cells targeting CCR9 and CD1a for the treatment of T cell acute lymphoblastic leukemia
    N Tirado, K Fidyt, MJ Mansilla, A Garcia-Perez, A Martinez-Moreno, ...
    Journal of Hematology & Oncology 18 (1), 69 , 2025
    2025
    Citations: 10
  • Fanconi-like anemia related to a FANCM mutation
    JA Encarnación, P Cerezuela, I Español, MR García, C Manso, ...
    European Journal of Medical Genetics 65 (1), 104399 , 2022
    2022
    Citations: 10
  • Therapeutic research in the crystal chromosome disease Fanconi anemia
    J Minguillon, J Surralles
    Mutation Research/Genetic Toxicology and Environmental Mutagenesis 836, 104-108 , 2018
    2018
    Citations: 8