Thirunavukkarasu

Scopus Publications

Azadirachta indica Leaf Extract Mediated Green Synthesized Vanadium Nanoparticles Exhibit Potent Anticancer Activity against Hepatocellular Carcinoma in Hep3B Cells and in vivo, Compared with Sorafenib and Combination Treatment
Shreyoshi Guha, Sancharan Acharya, Chandrabose Sureka, Chinnasamy Thirunavukkarasu
Bionanoscience, 2026
Transcriptional profiling and in silico investigations reveal novel nutraceutical formulation dwindling lipid accumulation in oleic acid induced high-fat hepatocytes through modulating RPPH1, RMRP, RN7SK, and TACSTD2 genes
Sancharan Acharya, Thirunavukkarasu Chinnasamy
Journal of Food Science and Technology, 2026
Therapeutic potential of ECP-SA1: A novel lytic phage against multidrug-resistant Escherichia coli
Sancharan Acharya, Thirunavukkarasu Chinnasamy
Microbial Pathogenesis, 2025
Sequential optimization for biomass and fucoxanthin enriched carotenoid production of Isochrysis galbana
Vijayakumar Maduraimuthu, Shenbhagaraman Ramalingam, Thirunavukkarasu Chinnasamy, Raja Rathinam, Babu Saranam, Jayappriyan Kothilmozhian Ranishree
Biocatalysis and Agricultural Biotechnology, 2025
Metal Oxide Nanoparticles Having Strong Physico- and Electrochemical Interaction with Genetic Material Will Have Better Anticancer Efficacy
Venugopal Sujatha, Gunaseelan Kaviyasri, Shreyoshi Guha, Sancharan Acharya, Thiyagarajan Ramesh, Chinnasamy Thirunavukkarasu
Bionanoscience, 2025
Critical Role of Phytochemicals in Gut-Microbiota-Associated Liver Cancer
Sancharan Acharya, Chinnasamy Thirunavukkarasu
Liver Cancer and Phytomedicine Chemoprevention Chemo Sensitization and Chemotherapy Strategies, 2025
Green-synthesized titanium dioxide nanoparticles with pyrogallol functionalization: A novel approach using cow dung extract for anticancer applications
Acharya, Sancharan, Behera, Akanksha, CS, Aswathy, Venugopal, Sujatha, Thiyagarajan, Ramesh, et al.
International Journal of Nano Dimension, 2025
Growing interest has been shown in the environment friendly synthesis of metal nanoparticles, yet no published research exists on synthesizing titanium dioxide nanoparticles (TiO2NPs) using cow dung extract (CD). In this manuscript, we synthesized TiO2NPs using CD extract (CD-TiO2) and functionalized them with pyrogallol (P-CD-TiO2). The physicochemical characteristics of the TiO2NPs were evaluated using UV-Vis spectroscopy, dynamic light scattering, Fourier-transform infrared spectroscopy, Raman spectroscopy, X-ray photoelectron spectroscopy, X-ray diffraction and scanning electron microscopy. The qualitative analysis of CD extract and biological activities of CD-TiO2 and P-CD-TiO2 were evaluated. The potential anticancer activity was examined in vitro against Hep3B using the MTT assay. The hydrodynamic size of CD-TiO2 and P-CD-TiO2NPs were 147.9nm and 183.4nm, respectively. The CD-TiO2 and P-CD-TiO2 were spherical in shape, with an average size ranging from 32nm to 48nm. CD-TiO2 and P-CD-TiO2 showed anti-hemolytic, anti-inflammatory, antioxidant activity, and significant cytotoxicity against Hep3B cells. The IC50 of CD-TiO2 was 379.9 μg/mL, while P-CD-TiO2 showed a significantly higher cytotoxic with an IC50 of 31.98 μg/mL. The results revealed that CD extract is effective reducing agents for TiO2 nanoparticles synthesis. Notably, the green-synthesized P-CD-TiO2NPs exhibited promising anticancer potential in concentration-dependent manner while being safe for red blood cells.
Elucidation of escitalopram oxalate and related antidepressants as putative inhibitors of PTP4A3/PRL-3 protein in hepatocellular carcinoma: A multi-computational investigation
Ishfaq Hassan Mir, Kankipati Teja Shyam, Susmida Seni Balakrishnan, Muthuvel Suresh Kumar, Thiyagarajan Ramesh, Chinnasamy Thirunavukkarasu
Computational Biology and Chemistry, 2024
Gut Microbiome and Cancer: From Cancer Development to Therapeutics with a Special Focus on Hepatocellular Carcinoma
Sancharan Acharya, Chinnasamy Thirunavukkarasu
Frontiers in Bioscience Landmark, 2024
The body of a human has a vast array of microorganisms termed the microbiome that impacts almost every function of the body. Gene-environment interactions play a major role in making us susceptible to cancer and the microbiome is such an environmental factor that we are exposed to from the very beginning of our lives to the very end. Increasing pieces of evidence are pointing towards an association of cancer and the microbiome. The bacteria inside our body might help us prevent some cancers as well as may increase the risk of carcinogenesis and treatment responses. Many studies are suggesting that tinkering with the microbiome might be a new way to treat and prevent many kinds of cancer. Although information on the roles of the microbiome in carcinogenesis is scant and almost no direct links have been found between these two yet. This review offers some of the recent evidences of the association between cancer and the microbiome, discuss the impact of gut bacteria on cancer and provide a detailed discussion on gut microbiota mediated therapeutic approaches with a special focus on Hepatocellular Carcinoma. The implementation of the new knowledge discovered in this subject calls for a great deal of research.
Phyto-assisted eco-friendly fabrication of haemocompatible vanadium nanoparticles using Azadirachta indica leaf extract inherent with antioxidant and anti-bacterial activity
Shreyoshi Guha, Sancharan Acharya, Thirunavukkarasu Chinnasamy
Particulate Science and Technology, 2024
In the present investigation, vanadium nanoparticles (VNPs) were synthesized through green process that entailed the use of Azadirachta indica leaf extract from sodium metavanadate. The characterization of VNPs involved a multitude of techniques, namely UV-Vis spectroscopy, Dynamic light scattering (DLS), Fourier transform infrared (FT-IR) spectroscopy, Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), Transmission electron microscopy (TEM) and Scanning electron microscopy (SEM). Analytical studies, such as UV-Vis spectra, established the band gap of 2.5 eV, demonstrating the semi-conductive nature of VNPs. According to DLS analysis, nanoparticles (NPs) had an average size of 113 nm. The subsequent characterization techniques validated the rod-shaped and crystalline structure of the NPs. Following the effective synthesis of NPs, antioxidant studies determined their in vitro radicle quenching competence against superoxide, hydrogen peroxide, and DPPH radicles. The VNPs exhibited an outstanding antioxidant potential and displayed a prominent protective effect in chicken erythrocytes subjected to H2O2-induced oxidative stress. Furthermore, VNPs were evaluated for anti-bacterial efficacy against various bacterial species, including Klebsiella aerogenes, Escherichia coli, Staphylococcus aureus, Klebsiella pneumonia, and Lactobacillus acidophilus, showing zones of inhibition at low doses. Thus, VNPs from Azadirachta indica leaf extract could be utilized in medicine as a preventative measure against oxidative stress and bacterial disorders.
Biogenic Zinc Oxide Nanoparticles Attenuate Acute Lymphoblastic Leukemia Cell Proliferation through Oxidative Stress and DNA Damage
Venugopal Sujatha, Alagesan Venkatesan, Acharya Sancharan, Chinnasamy Thirunavukkarasu
Pharmaceutical Sciences, 2024
Elucidation of 7,8-dihydroxy flavone in complexing with the oxidative stress-inducing enzymes, its impact on radical quenching and DNA damage: an in silico and in vitro approach
Ishfaq Hassan Mir, Aswathy Sheeja Anilkumar, Shreyoshi Guha, Amaresh Kumar Mohanty, Muthuvel Suresh Kumar, Venugopal Sujatha, Thiyagarajan Ramesh, Chinnasamy Thirunavukkarasu
Journal of Biomolecular Structure and Dynamics, 2024
Deciphering the calf thymus DNA binding potential of 5FU conjugated copper oxide nanoparticles along with its antiproliferative effects on liver cancer cells: A molecular, in silico, and in vitro approach
Jajnasenee Behera, Ishfaq Hassan Mir, Kankipati Teja Shyam, Shreyoshi Guha, Venugopal Sujatha, Chikkonda Raghavendar, Chinnasamy Thirunavukkarasu
Journal of Molecular Structure, 2023
Multi-spectroscopic Analysis Decodes the Interaction of Vanadium Nanoparticles with Calf Thymus DNA and Its Anticancer Effect Against Hepatocellular Carcinoma
Shreyoshi Guha, Kiruthiga Nancy, Ishfaq Hassan Mir, Valluru Lokanatha, Raghavendar Chikkonda, Venugopal Sujatha, Amaresh Kumar Mohanty, Muthuvel Suresh Kumar, Chinnasamy Thirunavukkarasu
Journal of Cluster Science, 2023
The relevance of acid sphingomyelinase as a potential target for therapeutic intervention in hepatic disorders: current scenario and anticipated trends
Ishfaq Hassan Mir, Chinnasamy Thirunavukkarasu
Archives of Toxicology, 2023
Selenium Nanoparticles Show Anticancer Activity Through Regulation of HIF-1α and HIF-2α Under Hypoxic Condition in Liver Cancer Cells
Sancharan Acharya, Subramaniyam Nithyananthan, Chinnasamy Thirunavukkarasu
DNA and Cell Biology, 2023
Biomimetic formation of silver oxide nanoparticles through Diospyros montana bark extract: Its application in dye degradation, antibacterial and anticancer effect in human hepatocellular carcinoma cells
Venugopal Sujatha, Gunaseelan Kaviyasri, Alagesan Venkatesan, Chinnasamy Thirunavukkarasu, Sancharan Acharya, Salman Bin Dayel, Sameer Al-Ghamdi, Mohammad Hassan Abdelzaher, Mohammad Shahid, Thiyagarajan Ramesh
Journal of King Saud University Science, 2023
Selenium conditioning decreases antioxidant enzyme activity and delays germination potency of Macrotyloma uniflorum and Vigna radiate
Subramaniyam Nithyananthan, Sen Somenath, Biddika Sreenadh, Chinnasamy Thirunavukkarasu, Nasraddin Othman Bahakim, Mohammad Shahid, Mohammad Hassan Abdelzaher, Abubucker Peer Mohideen, Thiyagarajan Ramesh, Valluru Lokanatha
Journal of King Saud University Science, 2023
Hepatocellular Carcinoma and Human Gut Microbiome: Association with Disease and Scope for Therapeutic Intervention
Ishfaq Hassan Mir, Saqib Hassan, Joseph Selvin, Chinnasamy Thirunavukkarasu
Human Microbiome in Health Disease and Therapy, 2023
Epigenetics and mitochondrial dysfunction insights into the impact of the progression of non-alcoholic fatty liver disease
Shreyoshi Guha, Selvam Sesili, Ishfaq Hassan Mir, Chinnasamy Thirunavukkarasu
Cell Biochemistry and Function, 2023
Inhibition of glutathione generation in hepatic steatotic rats augments oxidative stress
Krishnan Silja, Natarajan Selvaganabathy, Thiyagarajan Kalaiselvi, Chinnasamy Thirunavukkarasu
Toxicology Mechanisms and Methods, 2023
The Human Breast Milk Microbiome: Establishment and Resilience of Microbiota over the Mother–Infant Relationship
Saqib Hassan, Ishfaq Hassan Mir, Meenatchi Ramu, Ayushi Rambia, Chinnasamy Thirunavukkarasu, George Seghal Kiran, Pallaval Veera Bramhachari, Joseph Selvin
Human Microbiome in Health Disease and Therapy, 2023
The prominence of potential biomarkers in the diagnosis and management of hepatocellular carcinoma: Current scenario and future anticipation
Ishfaq Hassan Mir, K. C. Jyothi, Chinnasamy Thirunavukkarasu
Journal of Cellular Biochemistry, 2022
Transcriptional profiling reveals ataxia telangiectasia mutated pathways regulate joint copper and arsenic toxicity for hepatic metalloplasia and anti-cancer therapies
Chinnasamy Thirunavukkarasu, Yogeshwar Sharma, Tatyana Tchaikovskaya, Alexander Y. Maslov, Sanjeev Gupta
Life Sciences, 2022
Effect of Titanium, Silver and Zinc Nanoparticles on Microalgae in the Aquatic Environment
Arularasi Thenarasu, Chai Mee Kin, Wong Ling Shing, Sinouvassane Djearamane, Chinnasamy Thirunavukkarasu
Journal of Experimental Biology and Agricultural Sciences, 2022
A Mechanistic Review on Plant-derived Natural Inhibitors of Human Coronaviruses with Emphasis on SARS-COV-1 and SARS-COV-2
S.S.K. Durairajan, S.K. Guguloth, A.R. Lakshmi, R. Rajendran, K. Rajaram, T. Chinnasamy, J.-D. Huang, H. Zhang, S. Senapati
Current Drug Targets, 2022
Enhanced hepatocyte survival and anti-apoptosis via Akt by Diallyl trisulfide, augments hepatic regeneration through hydrogen sulfide in partially hepatectomized rats
S. Nithyananthan, Shreyoshi Guha, Ishfaq Hassan Mir, C. Thirunavukkarasu
Phytomedicine Plus, 2021
Targeting molecular signal transduction pathways in hepatocellular carcinoma and its implications for cancer therapy
Ishfaq Hassan Mir, Shreyoshi Guha, Jajnasenee Behera, Chinnasamy Thirunavukkarasu
Cell Biology International, 2021
Potential of Fruit Peel Waste in Growing Cyanobacteria Anabaena cylindrica
Tan Yeong Hwang, Ho An Qi, Chai Mee Kin, Wong Ling Shing, Djearamane Sinouvassane, Thirunavukkarasu Chinnasamy
International Journal of Technology, 2021
Prevalence of microplastics in the sediments of Odisha beaches, southeastern coast of India
Arunkumar Patchaiyappan, Syed ZakiAhmed, Kaushik Dowarah, Swapna Sarika Khadanga, Tejaswini Singh, Shanmuganathan Jayakumar, Chinnasamy Thirunavukkarasu, Suja P. Devipriya
Marine Pollution Bulletin, 2021
Prevalence and characteristics of microplastics present in the street dust collected from Chennai metropolitan city, India
Arunkumar Patchaiyappan, Kaushik Dowarah, Syed Zaki Ahmed, Manivannan Prabakaran, Shanmuganathan Jayakumar, Chinnasamy Thirunavukkarasu, Suja P. Devipriya
Chemosphere, 2021
Synthesis and characterization of novel bioactive azo compounds fused with benzothiazole and their versatile biological applications
Shanmugam Prakash, Govindharaj Somiya, Nagaraj Elavarasan, Kasivisvanathan Subashini, Selvaraj Kanaga, Ramamurthy Dhandapani, Magudeeswaran Sivanandam, Poomani Kumaradhas, Chinnasamy Thirunavukkarasu, Venugopal Sujatha
Journal of Molecular Structure, 2021
Isolation of hesperetin - A flavonoid from Cordia sebestena flower extract through antioxidant assay guided method and its antibacterial, anticancer effect on cervical cancer via in vitro and in silico molecular docking studies
Shanmugam Prakash, Nagaraj Elavarasan, Kasivisvanathan Subashini, Selvaraj Kanaga, Ramamurthy Dhandapani, Magudeeswaran Sivanandam, Poomani Kumaradhas, Chinnasamy Thirunavukkarasu, Venugopal Sujatha
Journal of Molecular Structure, 2020
Quantification of microplastics using Nile Red in two bivalve species Perna viridis and Meretrix meretrix from three estuaries in Pondicherry, India and microplastic uptake by local communities through bivalve diet
Kaushik Dowarah, Arunkumar Patchaiyappan, Chinnasamy Thirunavukkarasu, Shanmuganathan Jayakumar, Suja P. Devipriya
Marine Pollution Bulletin, 2020
Curcuma longa and Trigonella foenum graecum-enriched nutrient mixture from germinated Macrotyloma uniflorum and Vigna radiate ameliorate nonalcoholic fatty liver diseases in rats
Subramaniyam Nithyananthan, Dangudubiyyam Sushmaa, Ibansiewdor Myrthong, Lokanatha Valluru, Shreyoshi Guha, Ishfaq Hassan Mir, Jajnasenee Behera, Chinnasamy Thirunavukkarasu
Journal of Food Biochemistry, 2020
Arsenic trioxide, a cancer chemo drug hampers fibrotic liver regeneration by interrupting oxidative stress rekindling and stellate cell rejuvenation
Subramaniyam Nithyananthan, Chinnasamy Thirunavukkarasu
Journal of Cellular Physiology, 2020
The biosynthesis of a graphene oxide-based zinc oxide nanocomposite using: Dalbergia latifolia leaf extract and its biological applications
Elavarasan Nagaraj, Prakash Shanmugam, Kokila Karuppannan, Thirunavukkarasu Chinnasamy, Sujatha Venugopal
New Journal of Chemistry, 2020
Nutrient mixture from germinated legumes: Enhanced medicinal value with herbs-attenuated liver cirrhosis
Subramaniyam Nithyananthan, Pushparaj Keerthana, Srinivasan Umadevi, Shreyoshi Guha, Ishfaq Hassan Mir, Jajnasenee Behera, Chinnasamy Thirunavukkarasu
Journal of Food Biochemistry, 2020
Chemotherapeutic doses of arsenic trioxide delays hepatic regeneration by oxidative stress and hepatocyte apoptosis in partial hepatectomy rat
Subramaniyam. Nithyananthan, Chinnasamy. Thirunavukkarasu
Toxicology and Applied Pharmacology, 2019
Phosphorylated abacavir analogue (ABC-1) has ameliorative action against Newcastle disease virus induced pathogenesis in chicken
K. A. Suresh, K. C. Venkata Subbaiah, C. Thirunavukkarasu, S. Chennakesavulu, A. Rachamallu, Naga Raju Chamarti, Rajendra Wudayagiri, Lokanatha Valluru
Biotechnology and Applied Biochemistry, 2019
Augmenter of liver regeneration enhances cell proliferation through the microRNA-26a/Akt/cyclin D1 pathway in hepatic cells
Parul Gupta, Teja Naveen Sata, Naushad Ahamad, Rakibul Islam, Ajay K. Yadav, Amit Mishra, Subramaniyam Nithyananthan, Chinnasamy Thirunavukkarasu, M.G. Sanal, Senthil K. Venugopal
Hepatology Research, 2019
Synthesis and characterisation of arsenic nanoparticles and its interaction with DNA and cytotoxic potential on breast cancer cells
Ariraman Subastri, Viswanathan Arun, Preeti Sharma, Ezhuthupurakkal Preedia babu, Arumugam Suyavaran, Subramaniyam Nithyananthan, Ghedeir M. Alshammari, Balakrishnan Aristatile, Venkataraman Dharuman, Chinnasamy Thirunavukkarasu
Chemico Biological Interactions, 2018
Protective role of germinated mung bean against progression of non-alcoholic steatohepatitis in rats: A dietary therapy to improve fatty liver health
Ghedeir M. Alshammari, Aristatile Balakrishnan, Thirunavukkarasu Chinnasamy
Journal of Food Biochemistry, 2018
Unveiling anticancer potential of glibenclamide: Its synergistic cytotoxicity with doxorubicin on cancer cells
Nithyananthan Subramaniyam, Suyavaran Arumugam, Preedia Babu Ezthupurakkal, Subastri Ariraman, Indrani Biswas, Suresh Kumar Muthuvel, Aristatile Balakrishnan, Ghedeir M. Alshammari, Thirunavukkarasu Chinnasamy
Journal of Pharmaceutical and Biomedical Analysis, 2018
Butein protects the nonalcoholic fatty liver through mitochondrial reactive oxygen species attenuation in rats
Ghedeir M. Alshammari, Aristatile Balakrishnan, Thirunavukkarasu Chinnasamy
Biofactors, 2018
Neutrophil extracellular traps in acrolein promoted hepatic ischemia reperfusion injury: Therapeutic potential of NOX2 and p38MAPK inhibitors
Suyavaran Arumugam, Kesthuru Girish Subbiah, Kempaiah Kemparaju, Chinnasamy Thirunavukkarasu
Journal of Cellular Physiology, 2018
Troxerutin with copper generates oxidative stress in cancer cells: Its possible chemotherapeutic mechanism against hepatocellular carcinoma
Ariraman Subastri, Arumugam Suyavaran, Ezhuthupurakkal Preedia Babu, Subramaniyam Nithyananthan, Rajamani Barathidasan, Chinnasamy Thirunavukkarasu
Journal of Cellular Physiology, 2018
Anticancer potential of ZnO nanoparticle-ferulic acid conjugate on Huh-7 and HepG2 cells and diethyl nitrosamine induced hepatocellular cancer on Wistar albino rat
Preedia Babu Ezhuthupurakkal, Subastri Ariraman, Suyavaran Arumugam, Nithyananthan Subramaniyan, Suresh Kumar Muthuvel, Premkumar Kumpati, Bharathidasan Rajamani, Thirunavukkarasu Chinnasamy
Nanomedicine Nanotechnology Biology and Medicine, 2018
Nimbolide attenuate the lipid accumulation, oxidative stress and antioxidant in primary hepatocytes
Ghedeir M. Alshammari, Aristatile Balakrishnan, Thirunavukkarasu Chinnasamy
Molecular Biology Reports, 2017
Size Dependent Uptake and Hemolytic Effect of Zinc Oxide Nanoparticles on Erythrocytes and Biomedical Potential of ZnO-Ferulic acid Conjugates
E. Preedia Babu, A. Subastri, A. Suyavaran, K. Premkumar, V. Sujatha, B. Aristatile, Ghedeir M. Alshammari, V. Dharuman, C. Thirunavukkarasu
Scientific Reports, 2017
2-Hydroxy-4-methoxy benzoic acid attenuates the carbon tetra chloride-induced hepatotoxicity and its lipid abnormalities in rats via anti-inflammatory and antioxidant mechanism
Ghedeir M. Alshammari, Aristatile Balakrishnan, Thirunavukkarasu Chinnasamy
Inflammation Research, 2017
Selenium nanoparticles synthesized in aqueous extract of Allium sativum perturbs the structural integrity of Calf thymus DNA through intercalation and groove binding
Preedia Babu Ezhuthupurakkal, Lokeswara Rao Polaki, Arumugam Suyavaran, Ariraman Subastri, Venugopal Sujatha, Chinnasamy Thirunavukkarasu
Materials Science and Engineering C, 2017
Effect of troxerutin on 2-aminoanthracene and DNA interaction and its anti-mutagenic property
A. Subastri, K. Harikrishna, M. Sureshkumar, Ghedeir M. Alshammari, B. Aristatile, C. Thirunavukkarasu
Biomedicine and Pharmacotherapy, 2017
Preconditioning methods in the management of hepatic ischemia reperfusion- induced injury: Update on molecular and future perspectives
Arumugam Suyavaran, Chinnasamy Thirunavukkarasu
Hepatology Research, 2017
Solanum torvum Swartz. fruit attenuates cadmium-induced liver and kidney damage through modulation of oxidative stress and glycosylation
C. H. Ramamurthy, A. Subastri, A. Suyavaran, K. C. V. Subbaiah, L. Valluru, C. Thirunavukkarasu
Environmental Science and Pollution Research, 2016
Exploration of disulfiram dealings with calf thymus DNA using spectroscopic, electrochemical and molecular docking techniques
A. Subastri, A. Durga, K. Harikrishna, M. Sureshkumar, K. Jeevaratnam, K.S. Girish, C. Thirunavukkarasu
Journal of Luminescence, 2016
Probing the interaction of troxerutin with transfer RNA by spectroscopic and molecular modeling
A. Subastri, C.H. Ramamurthy, A. Suyavaran, P. Lokeswara Rao, E. Preedia Babu, K. Hari Krishna, M. Suresh Kumar, C. Thirunavukkarasu
Journal of Photochemistry and Photobiology B Biology, 2015
Unconjugated Bilirubin exerts Pro-Apoptotic Effect on Platelets via p38-MAPK activation
Somanathapura K. NaveenKumar, Ram M. Thushara, Mahalingam S. Sundaram, Mahadevappa Hemshekhar, Manoj Paul, Chinnasamy Thirunavukkarasu, Basappa, Ganesh Nagaraju, Sathees C. Raghavan, Kesturu S. Girish, Kempaiah Kemparaju, Kanchugarakoppal S. Rangappa
Scientific Reports, 2015
Nutrient profile of porridge made from Eleusine coracana (L.) grains: effect of germination and fermentation
Ariraman Subastri, Chitteti Ramamurthy, Arumugam Suyavaran, Ramachandran Mareeswaran, Priyanka Mandal, Sandeep Rellegadla, Chinnasamy Thirunavukkarasu
Journal of Food Science and Technology, 2015
Spectroscopic and molecular docking studies on the interaction of troxerutin with DNA
A. Subastri, C.H. Ramamurthy, A. Suyavaran, R. Mareeswaran, P. Lokeswara Rao, M. Harikrishna, M. Suresh Kumar, V. Sujatha, C. Thirunavukkarasu
International Journal of Biological Macromolecules, 2015
Influence of age on the free-radical scavenging ability of CeO2 and Au/CeO2 nanoparticles
M. Anandkumar, C. H. Ramamurthy, C. Thirunavukkarasu, K. Suresh Babu
Journal of Materials Science, 2015
Synthesis and biological evaluation of isoindoloisoquinolinone, pyroloisoquinolinone and benzoquinazolinone derivatives as poly(ADP-ribose) polymerase-1 inhibitors
Arumugam Suyavaran, Chitteti Ramamurthy, Ramachandran Mareeswaran, Yagna Viswa Shanthi, Jayaraman Selvakumar, Selvaraj Mangalaraj, Muthuvel Suresh Kumar, Chinnasamy Ramaraj Ramanathan, Chinnasamy Thirunavukkarasu
Bioorganic and Medicinal Chemistry, 2015
TNF-α suppression by glutathione preconditioning attenuates hepatic ischemia reperfusion injury in young and aged rats
Arumugam Suyavaran, Chitteti Ramamurthy, Ramachandran Mareeswaran, Ariraman Subastri, Polaki Lokeswara Rao, Chinnasamy Thirunavukkarasu
Inflammation Research, 2015
Extracellularly synthesized ZnO nanoparticles interact with DNA and augment gamma radiation induced DNA damage through reactive oxygen species
E. Preedia Babu, A. Subastri, A. Suyavaran, P. Lokeshwara Rao, M. Suresh Kumar, K. Jeevaratnam, C. Thirunavukkarasu
Rsc Advances, 2015
(-)-Epigallocatechin-gallate (EGCG) stabilize the mitochondrial enzymes and inhibits the apoptosis in cigarette smoke-induced myocardial dysfunction in rats
Gokulakrishnan Adikesavan, Magendira Mani Vinayagam, Liyakath Ali Abdulrahman, Thirunavukkarasu Chinnasamy
Molecular Biology Reports, 2013
Green synthesis and characterization of selenium nanoparticles and its augmented cytotoxicity with doxorubicin on cancer cells
CH. Ramamurthy, K. S. Sampath, P. Arunkumar, M. Suresh Kumar, V. Sujatha, K. Premkumar, C. Thirunavukkarasu
Bioprocess and Biosystems Engineering, 2013
Phytochemical screening, antioxidant and antimicrobial activities of ethanolic extract of Tecoma Stans flowers
International Journal of Pharma and Bio Sciences, 2013
Crocin, a dietary colorant mitigates cyclophosphamide-induced organ toxicity by modulating antioxidant status and inflammatory cytokines
Sadashivaiah Jnaneshwari, Mahadevappa Hemshekhar, Martin Sebastin Santhosh, Kabburahalli Sunitha, Rammohan Thushara, Chinnasamy Thirunavukkarasu, Kempaiah Kemparaju, Kesturu Subbaiah Girish
Journal of Pharmacy and Pharmacology, 2013
The extra cellular synthesis of gold and silver nanoparticles and their free radical scavenging and antibacterial properties
CH. Ramamurthy, M. Padma, I. Daisy mariya samadanam, R. Mareeswaran, A. Suyavaran, M. Suresh Kumar, K. Premkumar, C. Thirunavukkarasu
Colloids and Surfaces B Biointerfaces, 2013
Inhibition of hyaluronidase by N-acetyl cysteine and glutathione: Role of thiol group in hyaluronan protection
K. Sunitha, P. Suresh, M. Sebastin Santhosh, M. Hemshekhar, R.M. Thushara, Gopal K. Marathe, C. Thirunavukkarasu, K. Kemparaju, M. Suresh Kumar, K.S. Girish
International Journal of Biological Macromolecules, 2013
Polyphenol contents and antioxidant activity of Brassica nigra (L.) Koch. leaf extract
R. Rajamurugan, N. Selvaganabathy, S. Kumaravel, CH. Ramamurthy, V. Sujatha, C. Thirunavukkarasu
Natural Product Research, 2012
Brassica nigra plays a remedy role in hepatic and renal damage
R. Rajamurugan, A. Suyavaran, N. Selvaganabathy, C. H. Ramamurthy, G. Pramodh Reddy, V. Sujatha, C. Thirunavukkarasu
Pharmaceutical Biology, 2012
Evaluation of Antioxidant, Radical Scavenging Activity and Polyphenolics Profile in Solanum torvum L. Fruits
CH. Ramamurthy, M. Suresh Kumar, V. Sujatha A. Suyavaran, R. Mareeswaran, C. Thirunavukkarasu
Journal of Food Science, 2012
Lactobacillus plantarum AS1 isolated from South Indian fermented food Kallappam suppress 1,2-dimethyl hydrazine (DMH)-induced colorectal cancer in male wistar rats
R. Satish Kumar, P. Kanmani, N. Yuvaraj, K. A. Paari, V. Pattukumar, C. Thirunavukkarasu, V. Arul
Applied Biochemistry and Biotechnology, 2012
Identification, quantification of bioactive constituents, evaluation of antioxidant and in vivo acute toxicity property from the methanol extract of Vernonia cinerea leaf extract
R. Rajamurugan, N. Selvaganabathy, S. Kumaravel, CH. Ramamurthy, V. Sujatha, M. Suresh Kumar, C. Thirunavukkarasu
Pharmaceutical Biology, 2011
Attenuation of the cardiac inflammatory changes and lipid anomalies by (-)-epigallocatechin-gallate in cigarette smoke-exposed rats
A. Gokulakrisnan, B. Jayachandran Dare, C. Thirunavukkarasu
Molecular and Cellular Biochemistry, 2011
Constitutive release of powerful antioxidant-scavenging activity by hepatic stellate cells: Protection of hepatocytes from ischemia/reperfusion injury
Noor Mohamed Jameel, Chinnasamy Thirunavukkarasu, Noriko Murase, Michael Cascio, John Prelich, Shuting Yang, Stephen A. K Harvey, Chandrashekhar R Gandhi
Liver Transplantation, 2010
P38-MAPK-and caspase-3- mediated superoxide-induced apoptosis of rat hepatic stellate cells: reversal by retinoic acid
Noor Mohamed Jameel, Chinnasamy Thirunavukkarasu, Tong Wu, Simon C. Watkins, Scott L. Friedman, Chandrashekhar R. Gandhi
Journal of Cellular Physiology, 2009
Augmenter of liver regeneration: An important intracellular survival factor for hepatocytes
Chinnasamy Thirunavukkarasu, Lian Fu Wang, Stephen A.K. Harvey, Simon C. Watkins, J. Richard Chaillet, John Prelich, Thomas E. Starzl, Chandrashekhar R. Gandhi
Journal of Hepatology, 2008
Sodium selenite enhances glutathione peroxidase activity and DNA strand breaks in hepatoma induced by N-nitrosodiethylamine and promoted by phenobarbital
C. Thirunavukkarasu, K. Premkumar, A. K. Sheriff, D. Sakthisekaran
Molecular and Cellular Biochemistry, 2008
Mechanisms of endotoxin-induced NO, IL-6, and TNF-α production in activated rat hepatic stellate cells: Role of p38 MAPK
Chinnasamy Thirunavukkarasu, Simon C. Watkins, Chandrashekhar R. Gandhi
Hepatology, 2006
Protective effect of saffron (Crocus sativus L.) aqueous extract against genetic damage induced by anti-tumor agents in mice
K Premkumar, C Thirunavukkarasu, S K Abraham, S T Santhiya, A Ramesh
Human and Experimental Toxicology, 2006
The inhibitory effect of sodium selenite on N-nitrosodiethylamine-induced and phenobarbital promoted liver tumourigenesis in rats based on the modulation of polyamine levels
C. Thirunavukkarasu, K. Premkumar, R. Jagadeeswaran, D. Sakthisekaran
Molecular and Cellular Biochemistry, 2005
Normal rat hepatic stellate cells respond to endotoxin in LBP-independent manner to produce inhibitor(s) of DNA synthesis in hepatocytes
Chinnasamy Thirunavukkarasu, Tadahiro Uemura, Lian Fu Wang, Simon C. Watkins, Chandrashekhar R. Gandhi
Journal of Cellular Physiology, 2005
Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice
K. Selvendiran, C. Thirunavukkarasu, J. Prince Vijeya Singh, R. Padmavathi, D. Sakthisekaran
Molecular and Cellular Biochemistry, 2005
Superoxide-induced apoptosis of activated rat hepatic stellate cells
Chinnasamy Thirunavukkarasu, Simon Watkins, Stephen A.K. Harvey, Chandrashekhar R. Gandhi
Journal of Hepatology, 2004
Response of human islets to isolation stress and the effect of antioxidant treatment
Rita Bottino, A.N. Balamurugan, Hubert Tse, C. Thirunavukkarasu, Xinhui Ge, Jennifer Profozich, Martha Milton, Audra Ziegenfuss, Massimo Trucco, Jon D. Piganelli
Diabetes, 2004
Antioxidant-associated chemoprevention by sodium selenite in N-nitrosodiethylamine-induced and phenobarbital-promoted hepatocarcinogenesis in rats
C. Thirunavukkarasu, E. Babu, A. S. Ebrahim, N. Chandramohan, D. Sakthisekaran
Cell Biochemistry and Function, 2004
Endothelin receptor antagonist TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats
C Thirunavukkarasu, Y Yang, V M Subbotin, S A K Harvey, J Fung, C R Gandhi
Gut, 2004
Influence of sodium selenite on glycoprotein contents in normal and N-nitrosodiethylamine initiated and phenobarbital promoted rat liver tumors
C. Thirunavukkarasu, D. Sakthisekaran
Pharmacological Research, 2003
Sodium selenite modulates tumour marker indices in N-nitrosodiethylamine-initiated and phenobarbital-promoted rat liver carcinogenesis
C. Thirunavukkarasu, D. Sakthisekaran
Cell Biochemistry and Function, 2003
Stabilization of membrane bound enzyme profiles by sodium selenite in N-nitrosodiethylamine induced and phenobarbital promoted hepatocarcinogenesis in rats
C. Thirunavukkarasu, D. Sakthisekaran
Biomedicine and Pharmacotherapy, 2003
Sodium selenite, dietary micronutrient, prevents the lymphocyte DNA damage induced by N-nitrosodiethylamine and phenobarbital promoted experimental hepatocarcinogenesis
C. Thirunavukkarasu, D. Sakthisekaran
Journal of Cellular Biochemistry, 2003
Effect of sodium selenite on lipids and lipid-metabolizing enzymes in N-nitrosodiethylamine-induced hepatoma-bearing rats
C. Thirunavukkarasu, K. Selvedhiran, J. Prince Vijaya Singh, P. Senthilnathan, D. Sakthisekaran
Journal of Trace Elements in Experimental Medicine, 2003
Effect of dietary selenite on N-nitrosodiethylamine-induced and phenobarbital promoted multistage hepatocarcinogenesis in rat: Reflection in some minerals
C. Thirunavukkarasu, D. Sakthisekaran
Biomedicine and Pharmacotherapy, 2003
Dietary influence of selenium on the incidence of N-nitrosodiethylamine-induced hepatoma with reference to drug and glutathione metabolizing enzymes
C. Thirunavukkarasu, J. Prince Vijeya Singh, M. Thangavel, K. Selvendiran, D. Sakthisekaran
Cell Biochemistry and Function, 2002
Chemopreventive efficacy of selenium against N-nitrosodiethylamine-induced hepatoma in albino rats
C. Thirunavukkarasu, J. Prince Vijeya Singh, K. Selvendiran, D. Sakthisekaran
Cell Biochemistry and Function, 2001
Effect of citrinin on biochemical markers studied in experimental rats
Biomedicine, 2001
Protective role of vitamin E, 2-deoxy-D-glucose, and taurine on perchloroethylene induced alterations in ATPases
Abdul Shukkur Ebrahim, Ellappan Babu, Chinnasamy Thirunavukkarasu, Dhanapal Sakthisekaran
Drug and Chemical Toxicology, 2001
Effect of selenium on N-nitrosodiethylamine-induced multistage hepatocarcinogenesis with reference to lipid peroxidation and enzymic antioxidants
C. Thirunavukkarasu, D. Sakthisekaran
Cell Biochemistry and Function, 2001
In vitro studies on the selective cytotoxic effect of crocetin and quercetin
R Jagadeeswaran, C Thirunavukkarasu, P Gunasekaran, Nalini Ramamurty, D Sakthisekaran
Fitoterapia, 2000
Inhibitory effect of selenium on N-nitrosodiethylamine and phenobarbital-promoted rat liver carcinogenesis
Chinnasamy THIRUNAVUKKARASU, Ramasamy JAGADEESWARAN, Ellappan BABU, Dhanapal SAKTHISEKARAN
Journal of Clinical Biochemistry and Nutrition, 2000
Protective efficacy of selenium on N-nitrosodiethylamineinduced alterations in carbohydrate metabolism, studied in experimental hepatoma
Medical Science Research, 1999

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