MICHALSKI
@pasteur.fr
Institut Pasteur
RESEARCH, TEACHING, or OTHER INTERESTS
Sensory Systems
RECENT SCHOLAR PUBLICATIONS
- Single-cell spatially resolved transcriptomic characterization of the developing mouse cochlea
P Jean, S Mechaussier, A Singh-Estivalet, C Trébeau, A Gaudin, LB Cano, ...
bioRxiv, 2026.01. 21.700589 , 2026
2026 - Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways (Adv. Sci. 46/2025)
A Buck, T Dupont, R Andrews Cavanagh, O Postal, J Bourien, JL Puel, ...
Advanced Science 12 (46), e73008 , 2025
2025 - Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways
A Buck, T Dupont, R Andrews Cavanagh, O Postal, J Bourien, J Puel, ...
Advanced Science 12 (46), e08777 , 2025
2025 - Cochlear gene therapy restores hearing and auditory processing in an atypical DFNB9 mouse model
N Benamer, H Le Ribeuz, C Felgerolle, C Calvet, O Postal, B Plion, ...
Communications Medicine 5 (1), 229 , 2025
2025
Citations: 3 - Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism (Adv. Sci. 19/2025)
M Gagliardini, S Mechaussier, C Campos Pina, M Morais, O Postal, ...
Advanced Science 12 (19), 2570147 , 2025
2025 - Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism
M Gagliardini, S Mechaussier, C Campos Pina, M Morais, O Postal, ...
Advanced Science 12 (19), 2410776 , 2025
2025
Citations: 4 - Safety and efficacy of GJB2-GT, an adeno associated vector-based gene therapy treatment candidate for the autosomal recessive non-syndromic deafness 1A (DFNB1A)
R Boudra, G Olivier, CT Van Ba, S Pierredon, AG Harrus, P Rambeau, ...
MOLECULAR THERAPY 33 (4) , 2025
2025 - GJB2 gene therapy-response of two pre-clinical mouse models of the most frequent form of human deafness, DFNB1
AV Heritier, A Lelli, A Singh-Estivalet, S Roux, N Mekdad, M Sudres, ...
HUMAN GENE THERAPY 36 (3-4), E266-E266 , 2025
2025 - Preclinical development of GJB2-GT as a treatment for the autosomal recessive non-syndromic deafness 1A (DFNB1A) using an adeno associated vector-based gene therapy
CT Van Ba, G Olivier, S Pierredon, AV Héritier, C Vaux, A Singh-Estivalet, ...
2025 - Detecting Central Auditory Processing Disorders in Awake Mice
C Dejean, T Dupont, E Verpy, N Gonçalves, S Coqueran, N Michalski, ...
Brain Sciences 13 (11), 1539 , 2023
2023
Citations: 4 - Single-cell transcriptomic profiling of the mouse cochlea: An atlas for targeted therapies
P Jean, F Wong Jun Tai, A Singh-Estivalet, A Lelli, C Scandola, ...
Proceedings of the National Academy of Sciences 120 (26), e2221744120 , 2023
2023
Citations: 69 - The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses
C Calvet, T Peineau, N Benamer, M Cornille, A Lelli, B Plion, G Lahlou, ...
Iscience 25 (12) , 2022
2022
Citations: 28 - Lateral line hair cells integrate mechanical and chemical cues to orient navigation
L Desban, J Roussel, O Mirat, FX Lejeune, L Keiser, N Michalski, C Wyart
bioRxiv, 2022.08. 31.505989 , 2022
2022
Citations: 10 - Characterizing subcutaneous cortical auditory evoked potentials in mice
O Postal, W Bakay, T Dupont, A Buck, É Daoud, C Petit, N Michalski, ...
Hearing Research 422, 108566 , 2022
2022
Citations: 11 - Central auditory deficits associated with genetic forms of peripheral deafness
N Michalski, C Petit
Human Genetics 141 (3), 335-345 , 2022
2022
Citations: 24 - Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis
S Boucher, FWJ Tai, S Delmaghani, A Lelli, A Singh-Estivalet, T Dupont, ...
Proceedings of the National Academy of Sciences 117 (49), 31278-31289 , 2020
2020
Citations: 67 - Severe forms of presbycusis are caused by very rare variants in genes underlying early-onset forms of deafness
S Boucher, F Tai, W Jun, A Lelli, S Delmaghani, A Singh-Estivalet, ...
EUROPEAN JOURNAL OF HUMAN GENETICS 28 (SUPPL 1), 201-202 , 2020
2020 - Spontaneous mouse behavior in presence of dissonance and acoustic roughness
O Postal, T Dupont, W Bakay, N Dominique, C Petit, N Michalski, ...
Frontiers in Behavioral Neuroscience 14, 588834 , 2020
2020
Citations: 13 - Mapping the fine-scale organization and plasticity of the brain vasculature
C Kirst, S Skriabine, A Vieites-Prado, T Topilko, P Bertin, G Gerschenfeld, ...
Cell 180 (4), 780-795. e25 , 2020
2020
Citations: 440 - Genes involved in the development and physiology of both the peripheral and central auditory systems
N Michalski, C Petit
Annual review of neuroscience 42 (1), 67-86 , 2019
2019
Citations: 47
MOST CITED SCHOLAR PUBLICATIONS
- Mapping the fine-scale organization and plasticity of the brain vasculature
C Kirst, S Skriabine, A Vieites-Prado, T Topilko, P Bertin, G Gerschenfeld, ...
Cell 180 (4), 780-795. e25 , 2020
2020
Citations: 440 - Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning
N Michalski, V Michel, A Bahloul, G Lefèvre, J Barral, H Yagi, ...
Journal of Neuroscience 27 (24), 6478-6488 , 2007
2007
Citations: 262 - Usherin, the defective protein in Usher syndrome type IIA, is likely to be a component of interstereocilia ankle links in the inner ear sensory cells
A Adato, G Lefèvre, B Delprat, V Michel, N Michalski, S Chardenoux, ...
Human molecular genetics 14 (24), 3921-3932 , 2005
2005
Citations: 229 - Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly
B Delprat, V Michel, R Goodyear, Y Yamasaki, N Michalski, A El-Amraoui, ...
Human molecular genetics 14 (3), 401-410 , 2005
2005
Citations: 226 - Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia
E Caberlotto, V Michel, I Foucher, A Bahloul, RJ Goodyear, E Pepermans, ...
Proceedings of the National Academy of Sciences 108 (14), 5825-5830 , 2011
2011
Citations: 178 - Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane
E Verpy, M Leibovici, N Michalski, RJ Goodyear, C Houdon, D Weil, ...
Journal of comparative neurology 519 (2), 194-210 , 2011
2011
Citations: 176 - Otoferlin acts as a Ca 2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses
N Michalski, JD Goutman, SM Auclair, J Boutet de Monvel, M Tertrais, ...
Elife 6, e31013 , 2017
2017
Citations: 164 - Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells
M Beurg, N Michalski, S Safieddine, Y Bouleau, R Schneggenburger, ...
Journal of Neuroscience 30 (40), 13281-13290 , 2010
2010
Citations: 161 - BMP signaling specifies the development of a large and fast CNS synapse
L Xiao, N Michalski, E Kronander, E Gjoni, C Genoud, G Knott, ...
Nature neuroscience 16 (7), 856-864 , 2013
2013
Citations: 108 - Harmonin-b, an actin-binding scaffold protein, is involved in the adaptation of mechanoelectrical transduction by sensory hair cells
N Michalski, V Michel, E Caberlotto, GM Lefèvre, AFJ Van Aken, ...
Pflügers Archiv-European Journal of Physiology 459 (1), 115-130 , 2009
2009
Citations: 98 - Defect in the gene encoding the EAR/EPTP domain-containing protein TSPEAR causes DFNB98 profound deafness
S Delmaghani, A Aghaie, N Michalski, C Bonnet, D Weil, C Petit
Human molecular genetics 21 (17), 3835-3844 , 2012
2012
Citations: 87 - Stiffness and tension gradients of the hair cell’s tip-link complex in the mammalian cochlea
M Tobin, A Chaiyasitdhi, V Michel, N Michalski, P Martin
Elife 8, e43473 , 2019
2019
Citations: 85 - Single-cell transcriptomic profiling of the mouse cochlea: An atlas for targeted therapies
P Jean, F Wong Jun Tai, A Singh-Estivalet, A Lelli, C Scandola, ...
Proceedings of the National Academy of Sciences 120 (26), e2221744120 , 2023
2023
Citations: 69 - Ultrarare heterozygous pathogenic variants of genes causing dominant forms of early-onset deafness underlie severe presbycusis
S Boucher, FWJ Tai, S Delmaghani, A Lelli, A Singh-Estivalet, T Dupont, ...
Proceedings of the National Academy of Sciences 117 (49), 31278-31289 , 2020
2020
Citations: 67 - Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction
B Libé-Philippot, V Michel, J Boutet de Monvel, S Le Gal, T Dupont, ...
Proceedings of the National Academy of Sciences 114 (30), 7765-7774 , 2017
2017
Citations: 57 - Genes involved in the development and physiology of both the peripheral and central auditory systems
N Michalski, C Petit
Annual review of neuroscience 42 (1), 67-86 , 2019
2019
Citations: 47 - PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIa
R Etournay, A El-Amraoui, A Bahloul, S Blanchard, I Roux, G Pézeron, ...
Journal of cell science 118 (13), 2891-2899 , 2005
2005
Citations: 46 - Genetics of auditory mechano-electrical transduction
N Michalski, C Petit
Pflügers Archiv-European Journal of Physiology 467 (1), 49-72 , 2015
2015
Citations: 44 - Robo3-driven axon midline crossing conditions functional maturation of a large commissural synapse
N Michalski, N Babai, N Renier, DJ Perkel, A Chédotal, ...
Neuron 78 (5), 855-868 , 2013
2013
Citations: 40 - Biallelic nonsense mutations in the otogelin-like gene (OTOGL) in a child affected by mild to moderate hearing impairment
C Bonnet, M Louha, N Loundon, N Michalski, E Verpy, L Smagghe, ...
Gene 527 (2), 537-540 , 2013
2013
Citations: 30
