Rajiv Ranjan

Scopus Publications

The emerging roles of yeasts as plant growth promoters: mechanisms, benefits, and agricultural applications
Soumya Sharma, Dipak T. Nagrale, Anurag Chaurasia, Rajiv Ranjan, Girish Kumar Jha, Sunil Kumar
World Journal of Microbiology and Biotechnology, 2026
A metagenomic survey of the rhizosphere bacterial community of P. longum from the herbal garden, Dayalbagh Educational Institute (D.E.I), Agra, India
Shivangi Mathur, Mrinalini Prasad, Sunil Kumar, Anurag Chaurasia, Rajiv Ranjan
World Journal of Microbiology and Biotechnology, 2026
Role of CRISPR in bioremediation of heavy metal(loid): a breakthrough in environmental biotechnology
Harshit Mangal, Shivangi Mathur, Sunil Kumar, Anurag Chaurasia, Rajiv Ranjan
World Journal of Microbiology and Biotechnology, 2026
De novo transcriptome profiling revealing genes involved in piperine biosynthetic pathway in Piper longum L
Mrinalini Prasad, Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Scientific Reports, 2025
Piper longum, commonly known as long pepper, is highly valued for its bioactive alkaloid piperine, which has diverse pharmaceutical and culinary applications. In this study, we used high-throughput sequencing and de novo transcriptome assembly to analyze the transcriptomes of P. longum leaves, roots, and spikes. Our dataset consisted of 173,381 high-quality transcripts, with functional annotations highlighting key pathways involved in lysine biosynthesis and secondary metabolite production. We identified 8041 simple sequence repeats (SSRs), primarily trinucleotide repeats, adding valuable genetic markers. Additionally, we uncovered 21,235 transcription factors (TFs) across 65 families, including bHLH, NAC, and MYB, which are essential in regulating metabolism. KEGG pathway analysis categorized 4730 transcripts into 377 pathways, focusing on piperine biosynthesis, including phenylpropanoid and L-lysine metabolism. Our research identified 14 expressed genes encoding enzymes crucial for tropane, piperidine, and pyridine alkaloid biosynthesis, shedding light on piperine production mechanisms. High-performance liquid chromatography (HPLC) revealed varying piperine concentrations, with spikes showing the highest content, followed by roots and leaves. This comprehensive analysis of the P. longum transcriptome offers valuable insights into the genetics and regulatory networks underlying piperine biosynthesis, identifying molecular markers and genes that hold significant potential for enhancing the plant's biological and pharmaceutical applications.
In-silico study of E169G and F242K double mutations in leucine-rich repeats (LRR) polygalacturonase inhibiting protein (PGIP) of Gossypium barbadense and associated defense mechanism against plant pathogens
Sneha Murmu, Mayank Rashmi, Dipak T. Nagrale, Tejasman Kour, Mahender Kumar Singh, Anurag Chaurasia, Santosh Kumar Behera, Raja Shankar, Rajiv Ranjan, Girish Kumar Jha, Shailesh P. Gawande, Neelakanth S. Hiremani, Y. G. Prasad, Sunil Kumar
Journal of Cotton Research, 2025
Background Polygalacturonase inhibiting proteins (PGIPs) play a pivotal role in plant defense against plant pathogens by inhibiting polygalacturonase (PG), an enzyme produced by pathogens to degrade plant cell wall pectin. PGIPs, also known as leucine-rich repeat pathogenesis-related (PR) proteins, activate the host’s defense response upon interaction with PG, thereby reinforcing the host defense against plant pathogens attacks. In Egyptian or extra-long staple cotton (Gossypium barbadense), the interaction between PGIP and PG is one of the crucial steps in the defense mechanism against major pathogens such as Xanthomonas citri pv. malvacearum and Alternaria macrospora, which are responsible for bacterial leaf blight and leaf spot diseases, respectively. Results To unravel the molecular mechanisms underlying these PR proteins, we conducted a comprehensive study involving molecular modeling, protein-protein docking, site-specific double mutation (E169G and F242K), and molecular dynamics simulations. Both wild-type and mutated cotton PGIPs were examined in the interaction with the PG enzyme of a bacterial and fungal pathogen. Our findings revealed that changes in conformations of double-mutated residues in the active site of PGIP lead to the inhibition of PG binding. The molecular dynamics simulation studies provide insights into the dynamic behaviour and stability of the PGIP-PG complexes, shedding light on the intricate details of the inhibitory and exhibitory mechanism against the major fungal and bacterial pathogens of G. barbadense, respectively. Conclusions The findings of this study not only enhance our understanding of the molecular interactions between PGs of Xanthomonas citri pv. malvacearum and Alternaria macrospora and PGIP of G. barbadense but also present a potential strategy for developing the disease-resistant cotton varieties. By variations in the binding affinities of PGs through specific mutations in PGIP, this research offers promising avenues for the development of enhanced resistance to cotton plants against bacterial leaf blight and leaf spot diseases.
Strategies for plant-virus disease management from gene editing to nanotechnology
Ambika Chaturvedi, Rajiv Ranjan
Physiology and Molecular Biology of Plants, 2025
Next-Generation Sequencing in Medicinal Plants: Recent Progress, Opportunities, and Challenges
Deeksha Singh, Shivangi Mathur, Mrinalini Prasad, Rajiv Ranjan
Journal of Plant Growth Regulation, 2025
Advances in RNAi-based nanoformulations: revolutionizing crop protection and stress tolerance in agriculture
Shivangi Mathur, Ambika Chaturvedi, Rajiv Ranjan
Nanoscale Advances, 2025
Nucleic acid-based therapeutics have the ability to tackle a wide range of diseases and stress tolerance that present significant obstacles for conventional approaches in agriculture.
Unlocking the potential of CRISPR tools and databases for precision genome editing
Pooja Saraswat, Rajiv Ranjan
Frontiers in Plant Science, 2025
Recent breakthroughs in CRISPR/Cas genome editing have transformed molecular biology research and offer significant potential across biotechnology and medicine. This has created a broad spectrum of computational tools and databases that aim to optimize each phase of the genome-edited workflow, from guide RNA design and off-target prediction through screening analysis and biological validation. Here, we survey major CRISPR tools and analyse their features in the context of precision genome editing. CRISPOR and CHOPCHOP versatile platform that provides robust guide RNA design for several species, integrated off-target scoring, and intuitive genomic locus visualization. This review gives an overview of these new resources that have been developed, grouped based on their functionalities like design of guide RNA, off-target predictions, genome-wide screens, and visualizations of the data. Furthermore, we discuss new trends in database development like their integration with genome browsers and implementation of machine learning. This review thus gives a useful overview of the dynamic field of CRISPR/Cas genome editing tools. It also serves as a helpful guide for researchers looking to utilize these tools in their research.
Antimicrobial nanoparticles: a new horizon to combat multidrug-resistant bacteria
Ambika Chaturvedi, Rajiv Ranjan
Frontiers in Nanotechnology, 2025
Antimicrobial nanoparticles (NPs) exhibit revolutionary potential against infections due to their unique physicochemical properties that enhance antimicrobial activity. Antimicrobial NPs employ various mechanisms and pathways, including ROS generation, cell membrane disruption, DNA and protein damage, interference with metabolic pathways, and the electron transport chain, that eventually lead to microbial cell death. They are more beneficial than conventional antibiotics and have broad-spectrum efficacy with lower risk of resistance. Specifically, antibacterial NPs have a wide range of applications in various fields, such as food safety (e.g., antimicrobial packaging), water purification, healthcare (e.g., wound healing, coatings on medical devices), agriculture (e.g., disease management, plant protection), and industrial products (e.g., textiles, personal care items). Despite their promising potential, challenges such as toxicity, environmental impact, and regulatory limitations remain critical for their sustainable use. This review aims to provide the critical insight into various antibacterial NPs applications, mechanisms of action, and future scope, highlighting their potential prospects for safe and optimal use.
Nano-enabled biosensors in early detection of plant diseases
Ambika Chaturvedi, Deepti Tripathi, Rajiv Ranjan
Frontiers in Nanotechnology, 2025
Green Technologies in the Extraction of Medicinal Plant Bioactive Compounds
Deeksha Singh, Shivangi Mathur, Kumar Abhinandan, Rajiv Ranjan
Green Biotechnology for Herbal and Medicinal Plant Metabolites, 2025
A new isolate of mungbean yellow mosaic India virus in Vigna mungo L. reported from a Dayalbagh field, Agra
Ambika Chaturvedi, Dipinte Gupta, Bikash Mandal, Rajiv Ranjan
Virus Genes, 2024
The ecosystem approach and environmental justice nexus in natural resource management
Vikas, Rajiv Ranjan
Environmental Nexus for Resource Management, 2024
Proteomics approaches in medicinal plant research and pharmacological studies
Riya Jain, Shruti Rohatgi, Deeksha Singh, Shivangi Mathur, Rajiv Ranjan
Plant Proteomics Implications in Growth Quality Improvement and Stress Resilience, 2024
Dataset on double mutation in PGIP of Glycine max improves defense to PG of Sclerotinia sclerotiorum
Mayank Rashmi, Sneha Murmu, Dipak T. Nagrale, Mahender Kumar Singh, Santosh Kumar Behera, Raja Shankar, Rajiv Ranjan, Girish Kumar Jha, Anurag Chaurasia, Sunil Kumar
Data in Brief, 2024
In silico Identification and Characterization of WRKY Superfamily in Capsella rubella
Dipinte Gupta, Pooja Saraswat, Hunny Waswani, Sunil Kumar, Rajiv Ranjan
Research Journal of Biotechnology, 2024
Metagenomics analysis of water samples collected from the Yamuna River of Agra city, India
Nupur Raghav, Pooja Saraswat, Sunil Kumar, Anurag Chaurasia, Rajiv Ranjan
World Journal of Microbiology and Biotechnology, 2024
Diosgenin biosynthesis investigation in medicinal herb (Tribulus terrestris) by transcriptome analysis
Parul Tyagi, Mrinalini Prasad, Shivangi Mathur, Rajiv Ranjan
Gene, 2024
Agroecological approaches to sustainable development
Vikas, Rajiv Ranjan
Frontiers in Sustainable Food Systems, 2024
Pattern recognition receptors as potential therapeutic targets for developing immunological engineered plants
Deeksha Singh, Shivangi Mathur, Rajiv Ranjan
Advances in Protein Chemistry and Structural Biology, 2024
Recent advances in plant translational genomics for crop improvement
Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Advances in Protein Chemistry and Structural Biology, 2024
Eco-metabolomic Studies of Medicinal Plants and Herbal Medicine
Hunny Waswani, Mrinalini Prasad, Rajiv Ranjan
Reference Series in Phytochemistry, 2024
CRISPR/Cas techniques used in plant disease management
Pooja Saraswat, Deeksha Singh, Ayushi Singh, Shivangi Mathur, Hunny Waswani, Rajiv Ranjan
Biocontrol Agents for Improved Agriculture, 2024
Applications of bio-based nanomaterials in environment and agriculture: A review on recent progresses
Pooja Saraswat, Shivani Singh, Mrinalini Prasad, Ranjita Misra, Vishnu D. Rajput, Rajiv Ranjan
Hybrid Advances, 2023
Biofertilizers and biofortification in future agriculture
Vikas, Rajiv Ranjan
Climate Resilient Agriculture, 2023
Cross talk of biostimulants with other signaling molecules under abiotic stress
Shruti Rohatgi, Riya Jain, Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Climate Resilient Agriculture, 2023
Genome-wide association studies and next-generation sequencing in plant response to environmental stress
Pooja Saraswat, Hunny Waswani, Rajiv Ranjan
Biology and Biotechnology of Environmental Stress Tolerance in Plants Sustainable Approaches for Enhancing Environmental Stress Tolerance, 2023
Role of nanoparticles in tolerance against different environmental stress
Biology and Biotechnology of Environmental Stress Tolerance in Plants Trace Elements in Environmental Stress Tolerance, 2023
CRISPR/Cas-mediated genome editing for improvement of plant traits
Crispr Cas Mediated Genome Editing in Plants, 2023
Transposable elements and polyploidy in plants
Plant Transposable Elements Biology and Biotechnology, 2023
Genome engineering in plants via transposable elements
Plant Transposable Elements Biology and Biotechnology, 2023
Genetic circuits in microbial biosensors for heavy metal detection in soil and water
Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Biochemical and Biophysical Research Communications, 2023
Comparative study of the pharmacological, phytochemical and biotechnological aspects of Tribulus terrestris Linn. and Pedalium murex Linn: An overview
Parul Tyagi, Rajiv Ranjan
Acta Ecologica Sinica, 2023
Phytohormones as Stress Mitigators in Plants
Hunny Waswani, Rajiv Ranjan
Mineral Biofortification in Crop Plants for Ensuring Food Security, 2023
China Root (Wolfiporia extensa (Peck) Ginns)
Jeetendra Singh, SK Soni, Rajiv Ranjan
Mushrooms Nutraceuticals and Functional Foods, 2023
Biochar for the Improvement of Crop Production
Jeetendra Singh, Santendra Kumar Soni, Rajiv Ranjan
Mineral Biofortification in Crop Plants for Ensuring Food Security, 2023
Zinc Finger Nuclease (ZFNs) and Transcription Activator-like Effector Nucleases (TALENs) Based Genome Editing in Enhancement of Anticancer Activity of Plants
Plant Derived Anticancer Drugs in the Omics Era Biosynthesis Functions and Applications, 2023
Roles of Strigolactone in Plant Growth and Development
Deeksha Singh, Shivangi Mathur, Rajiv Ranjan
Strigolactones Alkamides and Karrikins in Plants Recent Updates and Future Prospects, 2023
Production of phenolic secondary metabolites by fungal endophytes: importance and implication
Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Fungal Secondary Metabolites Synthesis and Applications in Agroecosystem, 2023
Sustainable agricultural approach to study interaction of plants and microbes
Parul Tyagi, Ayushi Singh, Pooja Saraswat, Ambika Chaturvedi, Rajiv Ranjan
Plant Microbe Interaction Recent Advances in Molecular and Biochemical Approaches Volume 2 Agricultural Aspects of Microbiome Leading to Plant Defence, 2023
Bioremediation of Hazardous Wastes Using Green Synthesis of Nanoparticles
Ayushi Singh, Parul Tyagi, Rajiv Ranjan, Svetlana N. Sushkova, Tatiana Minkina, Marina Burachevskaya, Vishnu D. Rajput
Processes, 2023
Upcoming progress of transcriptomics studies on plants: An overview
Parul Tyagi, Deeksha Singh, Shivangi Mathur, Ayushi Singh, Rajiv Ranjan
Frontiers in Plant Science, 2022
Alternative Fuels for Agriculture Sustainability: Carbon Footprint and Economic Feasibility
Shivangi Mathur, Hunny Waswani, Deeksha Singh, Rajiv Ranjan
Agriengineering, 2022
Remediation of heavy metal(loid) contaminated soil through green nanotechnology
Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Frontiers in Sustainable Food Systems, 2022
CRISPR-Cas system: a precise tool for plant genome editing
Pooja Saraswat, Rajiv Ranjan
Nucleus India, 2022
Delineation of molecular interactions of plant growth promoting bacteria induced β-1,3-glucanases and guanosine triphosphate ligand for antifungal response in rice: a molecular dynamics approach
Yachana Jha, Budheswar Dehury, S. P. Jeevan Kumar, Anurag Chaurasia, Udai B. Singh, Manoj Kumar Yadav, U. B. Angadi, Rajiv Ranjan, Minaketan Tripathy, R. B. Subramanian, Sunil Kumar, Jesus Simal-Gandara
Molecular Biology Reports, 2022
Increasing the Heavy Metals Accumulation Ability of Transgenic Plants by Expressing Bacterial Enzymes
Pooja Saraswat, Dipinte Gupta, Rajiv Ranjan
Managing Plant Production Under Changing Environment, 2022
Hazardous elements in plants: sources, effect and management
Parul Tyagi, Ayushi Singh, Rajiv Ranjan
Hazardous and Trace Materials in Soil and Plants Sources Effects and Management, 2022
Role of Insect Pest Management in Agriculture Conservation
Hunny Waswani, Anamika Gupta, Mrinalini Prasad, Rajiv Ranjan
Agrochemicals in Soil and Environment Impacts and Remediation, 2022
Detoxification of Sewage Sludge by Natural Attenuation and Application as a Fertilizer
Ambika Chaturvedi, Pooja Saraswat, Anamika Gupta, Mrinalini Prasad, Rajiv Ranjan
Sustainable Management and Utilization of Sewage Sludge, 2022
Impact of Pesticides on the Ecosystem
Shivani Singh, Anamika Gupta, Hunny Waswani, Mrinalini Prasad, Rajiv Ranjan
Agrochemicals in Soil and Environment Impacts and Remediation, 2022
Microbial Degradation of Wastewater
Nupur Raghav, Rajesh Nigam, Shivangi Mathur, Deeksha Singh, Rajiv Ranjan
Recent Trends in Wastewater Treatment, 2022
Synthetic Biology in Plants, a Boon for Coming Decades
Dipinte Gupta, Gauri Sharma, Pooja Saraswat, Rajiv Ranjan
Molecular Biotechnology, 2021
Development of efficient synthetic promoters derived from pararetrovirus suitable for translational research
Dipinte Gupta, Nrisingha Dey, Sadhu Leelavathi, Rajiv Ranjan
Planta, 2021
Mechanism and function of salicylate in plant toward biotic stress tolerance
Parul Tyagi, Ayushi Singh, Anamika Gupta, Mrinalini Prasad, Rajiv Ranjan
Emerging Plant Growth Regulators in Agriculture Roles in Stress Tolerance, 2021
In silico characterization of synthetic promoters designed from mirabilis mosaic virus and rice tungro bacilliform virus
Dipinte Gupta, Rajiv Ranjan
Virusdisease, 2020
Nano-contaminants: Sources and impact on agriculture
Mrinalini Prasad, Anamika Gupta, Rajiv Ranjan
Contaminants in Agriculture Sources Impacts and Management, 2020
Efficient transformation of agricultural waste in India
Mrinalini Prasad, Rajiv Ranjan, Akbar Ali, Deepika Goyal, Arti Yadav, Teg Bahadur Singh, Preksha Shrivastav, Prem Kumar Dantu
Contaminants in Agriculture Sources Impacts and Management, 2020
Brassicaceae Plants Response and Tolerance toWaterlogging and Flood
Mrinalini Prasad, Rajiv Ranjan
Brassicaceae Plants Response and Tolerance Towaterlogging and Flood, 2020
Molecular mechanism of plant adaptation and tolerance to cold stress
Dipinte Gupta, Anamika Gupta, Kritika Yadav, Rajiv Ranjan
Plant Ecophysiology and Adaptation Under Climate Change Mechanisms and Perspectives II Mechanisms of Adaptation and Stress Amelioration, 2020
Molecular basis of plant-microbe interaction in remediating organic pollutants
Mrinalini Prasad, Pooja Saraswat, Anamika Gupta, Rajiv Ranjan
Handbook of Bioremediation Physiological Molecular and Biotechnological Interventions, 2020
Physiological and molecular basis for remediation of pesticides
Anamika Gupta, Pooja Saraswat, Kritika Yadav, Mrinalini Prasad, Rajiv Ranjan
Handbook of Bioremediation Physiological Molecular and Biotechnological Interventions, 2020
Physiological and molecular basis for remediation of polyaromatic hydrocarbons
Pooja Saraswat, Kritika Yadav, Anamika Gupta, Mrinalini Prasad, Rajiv Ranjan
Handbook of Bioremediation Physiological Molecular and Biotechnological Interventions, 2020
Fabrication of biobeads expressing heavy metal-binding protein for removal of heavy metal from wastewater
Dipinte Gupta, Suresh Satpati, Anshuman Dixit, Rajiv Ranjan
Applied Microbiology and Biotechnology, 2019
Genome wide in silico analysis of AP2/ERF transcription factor in Arachis duranensis
Mrinalini Prasad, Chaturvedi Ambika, Saraswat Pooja, Prem Kumar Dantu, Rajiv Ranjan
International Conference on Bioinformatics and Systems Biology Bsb 2018, 2018
In silico comparative analysis of promoters derived from plant pararetroviruses
Dipinte Gupta, Rajiv Ranjan
Virusdisease, 2017
Efficient chimeric plant promoters derived from plant infecting viral promoter sequences.
Sefali Acharya, Rajiv Ranjan, Sitakanta Pattanaik, Indu B. Maiti, Nrisingha Dey
Planta, 2014
Erratum to Development of Vascular Tissue and Stress Inducible Hybrid-Synthetic Promoters Through Dof-1 Motifs Rearrangement (Cell Biochem Biophys, (2012), 63, (235-245), 10.1007/s12013-012-9359-9)
Rajiv Ranjan, Nrisingha Dey
Cell Biochemistry and Biophysics, 2013
Development and functional analysis of novel genetic promoters using DNA shuffling, hybridization and a combination thereof
Rajiv Ranjan, Sunita Patro, Bhubaneswar Pradhan, Alok Kumar, Indu B. Maiti, Nrisingha Dey
Plos One, 2012
Development of Vascular Tissue and Stress Inducible Hybrid-Synthetic Promoters Through Dof-1 Motifs Rearrangement
Rajiv Ranjan, Nrisingha Dey
Cell Biochemistry and Biophysics, 2012
The development of efficient plant promoters for transgene expression employing plant virus promoters
Sunita Patro, Deepak Kumar, Rajiv Ranjan, Indu B. Maiti, Nrisingha Dey
Molecular Plant, 2012
Development of useful recombinant promoter and its expression analysis in different plant cells using confocal laser scanning microscopy
Deepak Kumar, Sunita Patro, Rajiv Ranjan, Dipak K. Sahoo, Indu B. Maiti, Nrisingha Dey
Plos One, 2011
Efficient chimeric promoters derived from full-length and sub-genomic transcript promoters of Figwort mosaic virus (FMV)
Rajiv Ranjan, Sunita Patro, Sangeeta Kumari, Deepak Kumar, Nrisingha Dey, Indu B. Maiti
Journal of Biotechnology, 2011
An alternative method of promoter assessment by confocal laser scanning microscopy
Dipak K. Sahoo, Rajiv Ranjan, Deepak Kumar, Alok Kumar, Bhabani S. Sahoo, Sumita Raha, Indu B. Maiti, Nrisingha Dey
Journal of Virological Methods, 2009

Rajiv Ranjan

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