Periodontics, periodontal medicine, microbiology, epidemiology, and biostatistics.
101
Scopus Publications
4204
Scholar Citations
34
Scholar h-index
76
Scholar i10-index
Scopus Publications
Interdental Brushing and Obstetrical Outcomes in Nulliparous Pregnant Women: Insights From a Cluster Randomised Controlled Trial Denis Bourgeois, Aida Kanoute, Daouda Faye, Marta Mazur, Hervé Perrier, et al. Journal of Clinical Periodontology, 2026 Aim Pregnancy gingivitis is potentially modifiable, making it a promising target for preventive strategies to reduce adverse obstetrical outcomes. The primary objective of this study was to evaluate whether an interdental hygiene intervention in early pregnancy could reduce obstetrical complications. Exploratory analyses focused on potential biological pathways linking oral inflammation and obstetrical outcomes. Materials and Methods A two‐arm randomised controlled trial (RCT) with cluster allocation (1:1) was conducted in six antenatal clinics in Senegal among nulliparous women at 12 weeks. Participants received either a daily calibrated interdental brushing intervention (Intervention) or usual oral hygiene (Control). Follow‐up visits were scheduled at 5 and 8 months. The primary endpoint was a composite of preterm birth, low birth weight, small for gestational age or pre‐eclampsia, analysed exploratorily under the intention‐to‐treat principle. Results A total of 323 women were randomised (162 intervention, 161 control). The composite outcome occurred in 28.4% of the intervention group and 24.2% of the control group ( p = 0.449). After adjustment, the intervention was not significantly associated (aOR = 0.65; 95% CI: 0.39–1.10; p = 0.107). Exploratory analyses suggested that interdental bleeding and C‐reactive protein (CRP) could act as mediators, accounting for ~60% of the effect, with the remaining ~40% representing a direct effect. No intervention‐related adverse events were observed. Conclusion This RCT did not demonstrate a significant reduction in obstetrical complications with early interdental prophylaxis. However, the intervention was safe, acceptable and feasible within antenatal care, highlighting the need for adequately powered trials to clarify its potential clinical impact.
Subgingival Bacterial Microbiota Profile of People Living With HIV-1 Under HAART: A Systematic Review Tatiana Pinheiro de Macedo, Cristiane Gonçalves, Lucio Souza Gonçalves, Priscila Pereira Pavan Vidal, Josué da Costa Lima‐Junior, et al. Special Care in Dentistry, 2025 Objective This systematic review aimed to assess the available literature on the subgingival bacterial microbiota profiles of PLHIV undergoing HAART. Materials and Methods This research was conducted in accordance with the PRISMA guidelines. Electronic searches were performed in the Cochrane Library, LILACS, PubMed, and Science Direct databases to identify primary studies evaluating the subgingival bacterial microbiota of individuals living with HIV‐1 undergoing HAART. The search was performed by two independent researchers and covered the period from January 2001 to July 2022. Studies published in English, Portuguese, and Spanish were included. Results A total of 457 articles were initially retrieved. Of these, 9 met the eligibility criteria. The included studies revealed a high frequency of periodontal pathogens among individuals living with HIV‐1 on HAART, including Treponema denticola (44%, n = 4 studies) and Porphyromonas gingivalis (33%, n = 3 studies), as well as species not commonly found in patients with periodontal disease, such as Enterococcus faecalis (33%, n = 2 studies). Conclusions According to the present findings, the most frequently identified subgingival bacterial species in patients living with HIV‐1 and receiving antiretroviral therapy were T. denticola and P. gingivalis , without establishing a consistent or unique microbiological profile.
Periodontal Health in Individuals Living with HIV: An Exploratory and Descriptive Molecular Approach of Microbial Interspecific and Intraspecific Diversity in Brazilian Patients Patricia N. Olivares Ponce, Lana Bitencourt Chaves, Daiana de Souza Perce-da-Silva, Ana Luiza Carneiro-Alencar, Cinthia Magalhães Rodolphi, et al. Microorganisms, 2025 Oral manifestations of HIV infection can be an early sign of the disease and may indicate progression to AIDS. Although antiretroviral therapies, especially highly active antiretroviral therapy (HAART), have reduced the prevalence of HIV-related oral lesions, ongoing updates in diagnosis and treatment are essential due to the extended life expectancy of individuals living with HIV. Periodontal disease is a significant concern in these patients, influenced by altered immune responses and microbial dynamics, though the mechanisms are not fully understood. This exploratory study aimed to investigate the oral microbiota and periodontal disease prevalence in HIV-positive individuals by analyzing subgingival plaque samples from 24 patients. We identified 12 bacterial species using Polymerase Chain Reaction (PCR) and amplicon sequencing. Seven species were detected, with Filifactor alocis, Tannerella forsythia, and Porphyromonas endodontalis being the most common. Porphyromonas gingivalis was present in only 13.6% of samples, while T. forsythia was found in 58.3%. Genetic diversity was also observed in P. endodontalis and Selenomonas sputigena amplicons, with specific single nucleotide polymorphisms (SNPs) identified in both species. These results highlight the complex microbial interactions in the oral environments of people living with HIV, emphasizing the need for personalized diagnostic and therapeutic strategies for managing oral health in this population.
Association of anxiety, age and oral health-related quality of life with periodontitis: A case-control study Dionisia Cataldo, Leila Cristina Mourão, Lucio Souza Gonçalves, Antonio Canabarro International Journal of Dental Hygiene, 2024 OBJECTIVE This case-control study evaluated the association of sociodemographic profile, mental health disorders and oral health-related quality of life (OHRQoL) with periodontitis. METHODS Patients with periodontitis (PP, n = 50) and control patients (CP, n = 50) were allocated into 2 groups after a complete periodontal examination. Data collection included age, sex, marital status, education and application of 2 questionnaires: Hospital Anxiety and Depression Scale for the diagnosis of anxiety/depression and Impact Profile on Oral Health (OHIP-14) for classification of well-being. An adjusted multiple binary logistic regression analysis was performed to assess the effect of all studied covariates on periodontitis. RESULTS The results show that mean clinical attachment loss and periodontal probing depth were 5.92 (SD = 0.42) and 5.46 (SD = 0.78) in PP and 0.00 (SD = 0.00) and 2.85 (SD = 0.23) in CP, respectively (p < 0.001). The regression analysis demonstrated a significant effect on periodontitis for age (OR = 1.13; p < 0.0001; 95% CI: 1.07-1.20), with the PP having more people aged 50 years or older than CP, anxiety (OR = 1.25; p = 0.020; 95% CI: 1.04-1.50) and OHIP-14 (OR = 1.17; p < 0.0001; 95% CI: 1.08-1.226). CONCLUSIONS The findings showed a positive association between anxiety, OHRQoL and age with periodontitis.
Factors influencing the outcome of nonsurgical root canal treatment and retreatment: A retrospective study Adalberto R. Vieira, Juan Pacheco‐Yanes, Isbelia D. Gazzaneo, Mônica A. S. Neves, José F. Siqueira, et al. Australian Endodontic Journal, 2024 This study assessed the influence of diverse variables on the outcome of nonsurgical root canal treatment/retreatment. In general, 304 teeth from 218 patients were treated/retreated and the outcome evaluated by the periapical index (PAI). Teeth with apical periodontitis lesions that have not completely healed were classified as success or failure based on lenient and rigid criteria, respectively. Findings were evaluated using a logistic regression analysis. The overall success rates were 74% and 82% using the PAI‐rigid and lenient success criteria, respectively. Specifically for treatment, the success rates were 73% (rigid) and 82% (lenient), while for retreatment they were 78% (rigid) and 83% (lenient). The treatment outcome was negatively affected by overextension, presence of preoperative lesion, lesion size >10 mm, and higher number of treatment visits (with no intracanal medication). Regarding retreatment, the chance of success was greater for teeth with adequate coronal restorations.
Oral candidiasis in patients hospitalised in the intensive care unit: Diagnosis through clinical and cytopathological examinations Fabiane Marques dos Santos Freire, Letícia Côgo Marques, Natasha Camargo da Silva, Karin Soares Cunha, Danielle Castex Conde, et al. Cytopathology, 2023 OBJECTIVE To evaluate the prevalence and clinical aspects of oral candidiasis in patients hospitalised in the intensive care unit. METHODS This is a longitudinal and prospective study that included 48 participants hospitalised in the intensive care unit. Sociodemographic data, presence of systemic disorders, use of medications, laboratory tests, cause of hospital admission, type of breathing, and length of hospital stay were obtained from medical records. Oral clinical inspection and cytopathological examinations were performed on all participants. The diagnosis of clinical candidiasis was based on the presence of clinical alterations together with positive cytopathological examination results. The diagnosis of subclinical candidiasis was based on the absence of clinical lesions and a positive cytopathological examination. The absence of oral candidiasis was considered when the participant did not present oral lesions and had a negative cytopathological examination. RESULTS Clinical candidiasis was present in 18.8% of the 48 participants, and 45.8% of them had the subclinical form. Levels of urea (P = 0.005), creatinine (P = 0.009), haemoglobin (P = 0.009), haematocrit (P = 0.011), bands (P = 0.024), international normalised ratio (INR; P = 0.034), types of breathing (P = 0.017), length of hospital stay (P = 0.037), and outcome (P = 0.014) demonstrated statistically significant differences between the groups with and without oral candidiasis. CONCLUSIONS Clinical and subclinical forms of oral candidiasis are frequent in intensive care unit patients. Levels of urea, creatinine, haemoglobin, haematocrit, bands, INR, type of breathing, length of hospital stay, and outcome can be associated with the presence of candidiasis.
Oral Squamous Cell Carcinomas and Expression of Inflammatory Markers Revista Cubana De Estomatologia, 2023
Interdental brushing and obstetrical outcomes in nulliparous pregnant women: insights from a cluster randomised controlled trial D Bourgeois, A Kanoute, D Faye, M Mazur, H Perrier, R Ardan, C Clément, ... Journal of Clinical Periodontology 53 (3), 436-444 , 2026 2026 Citations: 3
Osteopontin Expression in Oral Potentially Malignant Disorders and Squamous Cell Carcinoma: Association with Early Invasion but Not with Dysplastic Grade MTL Ribeiro, TCRB dos Santos, AB de Azevedo, AR Santos-Silva, ... Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology , 2026 2026
Subgingival Bacterial Microbiota Profile of People Living With HIV‐1 Under HAART: A Systematic Review TP de Macedo, C Gonçalves, LS Gonçalves, PPP Vidal, JC Lima‐Junior, ... Special Care in Dentistry 45 (6), e70121 , 2025 2025
Bidirectional association between dental caries and body mass index in socially vulnerable adolescents: a group-based trajectory analysis BML Gonçalves, L Armada, TH Stea, MAB Rebelo, JC Carvalho, ... Journal of Dentistry, 106087 , 2025 2025
Apical Periodontitis and Maxillary Sinus Alterations: Results of an Exploratory Cross-Sectional Tomographic In Vivo Study T Coutinho, L Gonçalves, MFV Marceliano-Alves, VR Figueiredo, ... Sinusitis 9 (2), 16 , 2025 2025
Histological criteria predictive of epithelial dysplasia in oral leukoplakia CFB Costa, AB de Azevedo, TCRB dos Santos, MA Lopes, ... Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 139 (5), e134 , 2025 2025
Periodontal health in individuals living with HIV: An exploratory and descriptive molecular approach of microbial interspecific and intraspecific diversity in brazilian patients PNO Ponce, LB Chaves, DS Perce-da-Silva, AL Carneiro-Alencar, ... Microorganisms 13 (4), 867 , 2025 2025 Citations: 4
The role of angioplasty in spontaneous coronary dissection M Duarte Almeida, JG Fiuza, GRM Ferreira, OC Kungel, FR Santos, ... European Heart Journal: Acute Cardiovascular Care 14 (Supplement_1), zuaf044 … , 2025 2025 Citations: 2
Gender differences in management of myocardial infarction in elderly patients G Ferreira, JG Fiuza, M Almeida, F Santos, O Kungel, JG Pereira, ... European Heart Journal: Acute Cardiovascular Care 14 (Supplement_1), zuaf044 … , 2025 2025
Antimicrobial effects of chlorhexidine gel associated with hyaluronic acid or cetylpyridinium chloride in a multispecies biofilm LV Mendes, BB Silva, FV Marques, TT Macedo, RC de Souza, ... REVISTA DELOS 18 (63), e3883-e3883 , 2025 2025
Factors influencing the outcome of nonsurgical root canal treatment and retreatment: A retrospective study AR Vieira, J Pacheco‐Yanes, ID Gazzaneo, MAS Neves, JF Siqueira Jr, ... Australian Endodontic Journal 50 (2), 245-259 , 2024 2024 Citations: 13
Association of anxiety, age and oral health‐related quality of life with periodontitis: A case‐control study D Cataldo, LC Mourão, LS Gonçalves, A Canabarro International Journal of Dental Hygiene 22 (3), 540-546 , 2024 2024 Citations: 12
Comparison of conventional and high sensitive cardiac troponin in pulmonary embolism risk assessement G Goncalo Ferreira, M Almeida, JG Fiuza, V Neto, O Kungel, F Santos, ... EUROPEAN JOURNAL OF HEART FAILURE 26, 533-533 , 2024 2024
Septal late gadolinum enhancement in acute myocarditis: is it worse? G Goncalo Ferreira, JG Fiuza, M Almeida, V Neto, F Santos, O Kungel, ... EUROPEAN JOURNAL OF HEART FAILURE 26, 505-506 , 2024 2024
Prediction of pacemaker implantation using FAINT score G Ferreira, M Almeida, JG Fiuza, V Neto, O Kungel, F Santos, ... EUROPEAN JOURNAL OF HEART FAILURE 26, 34-34 , 2024 2024
Exploring cardiac magnetic resonance accessibility and clinical significance in MINOCA: insights from a tertiary centre M Duarte Almeida, J Fiuza, G Ferreira, V Neto, L Goncalves, N Craveiro EUROPEAN JOURNAL OF HEART FAILURE 26, 450-450 , 2024 2024
SAMY score: a precision instrument for discriminating myocarditis from acute coronary syndrome M Duarte Almeida, J Fiuza, G Ferreira, V Neto, L Goncalves, N Craveiro EUROPEAN JOURNAL OF HEART FAILURE 26, 508-508 , 2024 2024
Exploring the Controversy: Dysplasia in Oral Lichen Planus-A Comparative Study Based on WHO Criteria and the Binary System LC Marques, DN Lopes, LS Gonçalves, KS Cunha, AS Junior, DC Conde 2024
81P Early access program: The reality of a Portuguese oncology center L Goncalves, C Lopes, S Torres, L Costa ESMO Open 9 , 2024 2024
Challenges in the assessment of epithelial dysplasia in oral lichen planus and oral lichenoid lesion: Inter and intra-observer variability of the WHO criteria and binary system LC Marques, LS Gonçalves, KS Cunha, AS Junior, DC Conde Journal of Clinical and Experimental Dentistry 16 (1), e62 , 2024 2024 Citations: 4
MOST CITED SCHOLAR PUBLICATIONS
The effect of sodium hypochlorite and chlorhexidine as irrigant solutions for root canal disinfection: a systematic review of clinical trials LS Gonçalves, RCV Rodrigues, CVA Junior, RG Soares, MV Vettore Journal of endodontics 42 (4), 527-532 , 2016 2016 Citations: 280
Antiviral activity of reagents in mouth rinses against SARS-CoV-2 F Carrouel, LS Gonçalves, MP Conte, G Campus, J Fisher, L Fraticelli, ... Journal of dental research 100 (2), 124-132 , 2021 2021 Citations: 214
Periradicular status and quality of root canal fillings and coronal restorations in an urban Colombian population JO Moreno, FRF Alves, LS Gonçalves, AM Martinez, IN Rôças, ... Journal of endodontics 39 (5), 600-604 , 2013 2013 Citations: 198
Cleaning and shaping oval canals with 3 instrumentation systems: a correlative micro–computed tomographic and histologic study MFLS Lacerda, MF Marceliano-Alves, AR Pérez, JC Provenzano, ... Journal of endodontics 43 (11), 1878-1884 , 2017 2017 Citations: 197
COVID-19: a recommendation to examine the effect of mouthrinses with β-cyclodextrin combined with citrox in preventing infection and progression F Carrouel, MP Conte, J Fisher, LS Gonçalves, C Dussart, JC Llodra, ... Journal of clinical medicine 9 (4), 1126 , 2020 2020 Citations: 193
Low survival rates of oral and oropharyngeal squamous cell carcinoma ACOV Le Campion, CMB Ribeiro, RR Luiz, FF da Silva Júnior, ... International journal of dentistry 2017 (1), 5815493 , 2017 2017 Citations: 158
Odontogenic sinusitis: a comprehensive review F Vidal, TM Coutinho, D Carvalho Ferreira, RC Souza, LS Gonçalves Acta Odontologica Scandinavica 75 (8), 623-633 , 2017 2017 Citations: 130
Glide path preparation in S-shaped canals with rotary pathfinding nickel-titanium instruments NCC Ajuz, L Armada, LS Gonçalves, G Debelian, JF Siqueira Jr Journal of endodontics 39 (4), 534-537 , 2013 2013 Citations: 126
Root canal disinfection by single-and multiple-instrument systems: effects of sodium hypochlorite volume, concentration, and retention time I Gazzaneo, GCS Vieira, AR Pérez, FRF Alves, LS Gonçalves, I Mdala, ... Journal of endodontics 45 (6), 736-741 , 2019 2019 Citations: 123
Effects of preparation with the self‐adjusting file, TRUS hape and XP‐endo shaper systems, and a supplementary step with XP‐endo finisher R on filling material removal during … AG Machado, BPS Guilherme, JC Provenzano, MF Marceliano‐Alves, ... International Endodontic Journal 52 (5), 709-715 , 2019 2019 Citations: 107
Endodontic-related facial paresthesia: systematic review FR Alves, MS Coutinho, LS Gonçalves J Can Dent Assoc 80 (80), e13 , 2014 2014 Citations: 99
Effects of increased apical enlargement on the amount of unprepared areas and coronal dentine removal: a micro‐computed tomography study AR Pérez, FRF Alves, MF Marceliano‐Alves, JC Provenzano, ... International Endodontic Journal 51 (6), 684-690 , 2018 2018 Citations: 96
Histobacteriologic conditions of the apical root canal system and periapical tissues in teeth associated with sinus tracts D Ricucci, S Loghin, LS Gonçalves, IN Rôças, JF Siqueira Jr Journal of endodontics 44 (3), 405-413 , 2018 2018 Citations: 95
Clinical and microbiological profiles of human immunodeficiency virus (HIV)–seropositive Brazilians undergoing highly active antiretroviral therapy and HIV‐Seronegative … LS Gonçalves, SM Soares Ferreira, CO Souza, R Souto, AP Colombo Journal of Periodontology 78 (1), 87-96 , 2007 2007 Citations: 95
Antibiofilm effects of endodontic sealers containing quaternary ammonium polyethylenimine nanoparticles J Barros, MG Silva, IN Rôças, LS Gonçalves, FF Alves, MA Lopes, ... Journal of endodontics 40 (8), 1167-1171 , 2014 2014 Citations: 90
Periodontal disease in HIV-infected adults in the HAART era: Clinical, immunological, and microbiological aspects LS Gonçalves, BML Gonçalves, TV Fontes Archives of oral biology 58 (10), 1385-1396 , 2013 2013 Citations: 86
Distribution of mast cells and macrophages and expression of interleukin-6 in periapical cysts IV Bracks, L Armada, LS Gonçalves, FR Pires Journal of Endodontics 40 (1), 63-68 , 2014 2014 Citations: 70
Influence of the geometry of curved artificial canals on the fracture of rotary nickel-titanium instruments subjected to cyclic fatigue tests HP Lopes, MVB Vieira, CN Elias, LS Gonçalves, JF Siqueira Jr, ... Journal of endodontics 39 (5), 704-707 , 2013 2013 Citations: 66
Association of T CD4 lymphocyte levels and subgingival microbiota of chronic periodontitis in HIV-infected Brazilians under HAART L de Souza Gonçalves, SM Ferreira, A Silva Jr, GE Villoria, LH Costinha, ... Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and … , 2004 2004 Citations: 60
Distribution of sodium hypochlorite throughout the mesial root canal system of mandibular molars after adjunctive irrigant activation procedures: a micro-computed tomographic study J Pacheco-Yanes, JC Provenzano, MF Marceliano-Alves, I Gazzaneo, ... Clinical oral investigations 24 (2), 907-914 , 2020 2020 Citations: 58
