Marjorie Whitfield

@iab-grenoble.fr

Institute for Advanced Biosciences - Team Physiology and Pathophysiology of Sperm cells
INSERM

Marjorie Whitfield


            Download Compact PDF  
https://researchid.co/marjwhit

EDUCATION

2017 : PhD Physiology and Molecular Genetics

RESEARCH, TEACHING, or OTHER INTERESTS

Physiology, Cell Biology, Molecular Biology
1083

Scholar Citations

16

Scholar h-index

17

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies
    E Cavarocchi, M Drouault, JC Ribeiro, V Simon, M Whitfield, A Touré
    Andrology , 2025
    2025
    Citations: 26
  • The annulus: composition, role and importance in sperm flagellum biogenesis and male fertility
    M Whitfield
    Basic and Clinical Andrology 34 (1), 25 , 2024
    2024
    Citations: 8
  • CCDC65 , encoding a component of the axonemal Nexin‐Dynein regulatory complex, is required for sperm flagellum structure in humans
    F Jreijiri, E Cavarocchi, A Amiri‐Yekta, C Cazin, SH Hosseini, E El Khouri, ...
    Clinical Genetics 105 (3), 317-322 , 2024
    2024
    Citations: 18
  • Results and perinatal outcomes from 189 ICSI cycles of couples with asthenozoospermic men and flagellar defects assessed by transmission electron microscopy
    A Boursier, A Boudry, V Mitchell, A Loyens, N Rives, A Moerman, ...
    Reproductive BioMedicine Online 47 (5), 103328 , 2023
    2023
    Citations: 6
  • Identification of IQCH as a calmodulin-associated protein required for sperm motility in humans
    E Cavarocchi, C Sayou, P Lores, C Cazin, L Stouvenel, E El Khouri, ...
    Iscience 26 (8) , 2023
    2023
    Citations: 4
  • TTC12 loss-of-function mutations cause primary ciliary dyskinesia and unveil distinct dynein assembly mechanisms in motile cilia versus flagella
    L Thomas, K Bouhouche, M Whitfield, G Thouvenin, A Coste, B Louis, ...
    EUROPEAN JOURNAL OF HUMAN GENETICS 31, 119-119 , 2023
    2023
  • Sperm ion transporters and channels in human asthenozoospermia: genetic etiology, lessons from animal models, and clinical perspectives
    E Cavarocchi, M Whitfield, F Saez, A Touré
    International journal of molecular sciences 23 (7), 3926 , 2022
    2022
    Citations: 39
  • Bi-allelic truncating variants in CFAP206 cause male infertility in human and mouse
    Q Shen, G Martinez, H Liu, J Beurois, H Wu, A Amiri-Yekta, D Liang, ...
    Human Genetics 140 (9), 1367-1377 , 2021
    2021
    Citations: 33
  • A missense mutation in IFT74, encoding for an essential component for intraflagellar transport of Tubulin, causes asthenozoospermia and male infertility without clinical signs …
    P Lores, ZE Kherraf, A Amiri-Yekta, M Whitfield, A Daneshipour, ...
    Human Genetics 140 (7), 1031-1043 , 2021
    2021
    Citations: 30
  • The sodium/proton exchanger SLC9C1 (sNHE) is essential for human sperm motility and fertility
    E Cavarocchi, M Whitfield, A Chargui, L Stouvenel, P Lorès, C Coutton, ...
    Clinical Genetics 99 (5), 684-693 , 2021
    2021
    Citations: 52
  • Correction to: A missense mutation in IFT74, encoding for an essential component for intraflagellar transport of Tubulin, causes asthenozoospermia and male infertility without …
    P Lorès, ZE Kherraf, A Amiri-Yekta, M Whitfield, A Daneshipour, ...
    Human genetics , 2021
    2021
  • Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility
    S Gadadhar, GA Viar, JN Hansen, A Gong, A Kostarev, C Ialy-Radio, ...
    Science 371 (6525) , 2021
    2021
    Citations: 146
  • Identification and Characterization of the Most Common Genetic Variant Responsible for Acephalic Spermatozoa Syndrome in Men Originating from North Africa
    C Cazin, Y Boumerdassi, G Martinez, S Fourati Ben Mustapha, ...
    International journal of molecular sciences 22 (4), 2187 , 2021
    2021
    Citations: 18
  • Bi-allelic DNAH8 variants lead to multiple morphological abnormalities of the sperm flagella and primary male infertility
    C Liu, H Miyata, Y Gao, Y Sha, S Tang, Z Xu, M Whitfield, C Patrat, H Wu, ...
    The American Journal of Human Genetics 107 (2), 330-341 , 2020
    2020
    Citations: 176
  • TTC12 loss-of-function mutations cause primary ciliary dyskinesia and unveil distinct dynein assembly mechanisms in motile cilia versus flagella
    L Thomas, K Bouhouche, M Whitfield, G Thouvenin, A Coste, B Louis, ...
    The American Journal of Human Genetics 106 (2), 153-169 , 2020
    2020
    Citations: 72
  • Les mutations de DNAH17 causent une infertilité isolée par asthénospermie par défaut d’une dynéine axonémale spécifique du flagelle des spermatozoïdes
    L Thomas, M Whitfield, É Béquignon, A Schmitt, L Stouvenel, G Montantin, ...
    Assises de génétique humaine et médicale , 2020
    2020
  • Mutations in TTC29, encoding an evolutionarily conserved axonemal protein, result in asthenozoospermia and male infertility
    P Lorès, D Dacheux, ZE Kherraf, JFN Mbango, C Coutton, L Stouvenel, ...
    The American Journal of Human Genetics 105 (6), 1148-1167 , 2019
    2019
    Citations: 64
  • Impairment of sperm maturation and capacitation due to diet‐dependent cholesterol overload
    F Saez, M Whitfield, JR Drevet
    Andrology 7 (5), 654-661 , 2019
    2019
    Citations: 7
  • Laurence Stouvenel, Guy Montantin, 7 Sylvie Tissier, 7 Philippe Duquesnoy, 4 Bruno Copin, 7 Sandra Chantot, 7 Florence Dastot, 7 Catherine Faucon, 8 Anne Laure Barbotin, 9, 10 …
    M Whitfield, L Thomas, E Bequignon, A Schmitt
    The American Journal of Human Genetics 105, 198-212 , 2019
    2019
  • Mutations in DNAH17, encoding a sperm-specific axonemal outer dynein arm heavy chain, cause isolated male infertility due to asthenozoospermia
    M Whitfield, L Thomas, E Bequignon, A Schmitt, L Stouvenel, G Montantin, ...
    The American Journal of Human Genetics 105 (1), 198-212 , 2019
    2019
    Citations: 202

MOST CITED SCHOLAR PUBLICATIONS

  • Mutations in DNAH17, encoding a sperm-specific axonemal outer dynein arm heavy chain, cause isolated male infertility due to asthenozoospermia
    M Whitfield, L Thomas, E Bequignon, A Schmitt, L Stouvenel, G Montantin, ...
    The American Journal of Human Genetics 105 (1), 198-212 , 2019
    2019
    Citations: 202
  • Bi-allelic DNAH8 variants lead to multiple morphological abnormalities of the sperm flagella and primary male infertility
    C Liu, H Miyata, Y Gao, Y Sha, S Tang, Z Xu, M Whitfield, C Patrat, H Wu, ...
    The American Journal of Human Genetics 107 (2), 330-341 , 2020
    2020
    Citations: 176
  • Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility
    S Gadadhar, GA Viar, JN Hansen, A Gong, A Kostarev, C Ialy-Radio, ...
    Science 371 (6525) , 2021
    2021
    Citations: 146
  • TTC12 loss-of-function mutations cause primary ciliary dyskinesia and unveil distinct dynein assembly mechanisms in motile cilia versus flagella
    L Thomas, K Bouhouche, M Whitfield, G Thouvenin, A Coste, B Louis, ...
    The American Journal of Human Genetics 106 (2), 153-169 , 2020
    2020
    Citations: 72
  • Comprehensive overview of murine epididymal mononuclear phagocytes and lymphocytes: unexpected populations arise
    A Voisin, M Whitfield, C Damon-Soubeyrand, C Goubely, J Henry-Berger, ...
    Journal of reproductive immunology 126, 11-17 , 2018
    2018
    Citations: 66
  • Mutations in TTC29, encoding an evolutionarily conserved axonemal protein, result in asthenozoospermia and male infertility
    P Lorès, D Dacheux, ZE Kherraf, JFN Mbango, C Coutton, L Stouvenel, ...
    The American Journal of Human Genetics 105 (6), 1148-1167 , 2019
    2019
    Citations: 64
  • The sodium/proton exchanger SLC9C1 (sNHE) is essential for human sperm motility and fertility
    E Cavarocchi, M Whitfield, A Chargui, L Stouvenel, P Lorès, C Coutton, ...
    Clinical Genetics 99 (5), 684-693 , 2021
    2021
    Citations: 52
  • Posttesticular sperm maturation, infertility, and hypercholesterolemia
    M Whitfield, X Pollet-Villard, R Levy, JR Drevet, F Saez
    Asian Journal of Andrology 17 (5), 742 , 2015
    2015
    Citations: 52
  • Sperm ion transporters and channels in human asthenozoospermia: genetic etiology, lessons from animal models, and clinical perspectives
    E Cavarocchi, M Whitfield, F Saez, A Touré
    International journal of molecular sciences 23 (7), 3926 , 2022
    2022
    Citations: 39
  • Bi-allelic truncating variants in CFAP206 cause male infertility in human and mouse
    Q Shen, G Martinez, H Liu, J Beurois, H Wu, A Amiri-Yekta, D Liang, ...
    Human Genetics 140 (9), 1367-1377 , 2021
    2021
    Citations: 33
  • Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse
    E El Khouri, M Whitfield, L Stouvenel, A Kini, B Riederer, P Lores, ...
    Molecular reproduction and development 85 (8-9), 682-695 , 2018
    2018
    Citations: 33
  • A missense mutation in IFT74, encoding for an essential component for intraflagellar transport of Tubulin, causes asthenozoospermia and male infertility without clinical signs …
    P Lores, ZE Kherraf, A Amiri-Yekta, M Whitfield, A Daneshipour, ...
    Human Genetics 140 (7), 1031-1043 , 2021
    2021
    Citations: 30
  • Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies
    E Cavarocchi, M Drouault, JC Ribeiro, V Simon, M Whitfield, A Touré
    Andrology , 2025
    2025
    Citations: 26
  • CCDC65 , encoding a component of the axonemal Nexin‐Dynein regulatory complex, is required for sperm flagellum structure in humans
    F Jreijiri, E Cavarocchi, A Amiri‐Yekta, C Cazin, SH Hosseini, E El Khouri, ...
    Clinical Genetics 105 (3), 317-322 , 2024
    2024
    Citations: 18
  • Identification and Characterization of the Most Common Genetic Variant Responsible for Acephalic Spermatozoa Syndrome in Men Originating from North Africa
    C Cazin, Y Boumerdassi, G Martinez, S Fourati Ben Mustapha, ...
    International journal of molecular sciences 22 (4), 2187 , 2021
    2021
    Citations: 18
  • Dyslipidemia alters sperm maturation and capacitation in LXR-null mice
    M Whitfield, R Guiton, J Rispal, N Acar, A Kocer, JR Drevet, F Saez
    Reproduction 154 (6), 827-842 , 2017
    2017
    Citations: 17
  • Liver X receptors (LXRs) alpha and beta play distinct roles in the mouse epididymis
    M Whitfield, A Ouvrier, R Cadet, C Damon-Soubeyrand, R Guiton, L Janny, ...
    Biology of reproduction 94 (3), 55, 1-11 , 2016
    2016
    Citations: 12
  • The annulus: composition, role and importance in sperm flagellum biogenesis and male fertility
    M Whitfield
    Basic and Clinical Andrology 34 (1), 25 , 2024
    2024
    Citations: 8
  • Impairment of sperm maturation and capacitation due to diet‐dependent cholesterol overload
    F Saez, M Whitfield, JR Drevet
    Andrology 7 (5), 654-661 , 2019
    2019
    Citations: 7
  • Results and perinatal outcomes from 189 ICSI cycles of couples with asthenozoospermic men and flagellar defects assessed by transmission electron microscopy
    A Boursier, A Boudry, V Mitchell, A Loyens, N Rives, A Moerman, ...
    Reproductive BioMedicine Online 47 (5), 103328 , 2023
    2023
    Citations: 6