Longevity of different in-office treatments for dentin hypersensitivity: A 6-month randomized and parallel clinical trial Fernanda de Souza e Silva Ramos, André Luiz Fraga Briso, Érika Mayumi Omoto, Edgar Dutra Zanotto, Paulo Henrique dos Santos, et al. Plos One, 2026 This longitudinal, randomized, parallel-design clinical trial aimed to evaluate the long-term effectiveness of different in-office treatments for dentin hypersensitivity (DH) over a 6-month period. A total of 192 teeth presenting DH associated with root surface exposure were treated with one of four desensitizing agents: fluoride varnish (Duraphat – FLU, active control), bioactive ceramic solution (Biosilicate – BIOS), universal self-etching adhesive (Single Bond Universal – SBU), and a bioactive, photoactivated varnish containing PRG fillers (SPRG). DH was assessed using a visual analogue scale (VAS) to analyse intensity of sensitivity and a computerized visual scale (CoVAS) to observe the time course of sensibility at baseline, 7, 15, 30 days and 6 months post-treatment. Comparisons between groups were conducted using Fisher’s exact test for qualitative variables and analysis of variance (ANOVA) for quantitative variables. Longitudinal outcomes (VAS and CoVAS) were evaluated using linear mixed-effects models, with post hoc comparisons performed using orthogonal contrasts. Statistical differences were found for VAS analysis (p < 0.05). Comparing the desensitizers, FLU showed higher sensitivity than SBU, after 7 days. Comparing follow-up periods, a significant reduction in DH beginning at 7 days for BIOS and SBU, and at 15 days for FLU and SPRG. Regarding CoVAS time course, FLU exhibited a significantly shorter time course than SBU, after 15 days and 6 months of follow-up (p ≤ 0.05). SPRG was the only treatment that showed no difference in reaction time between 6 months and baseline (p > 0.05). In conclusion, root exposure height and the presence of an antagonist tooth may influence the initial intensity of DH. All treatments reduced DH over 6 months. Only bioactive resin varnish maintained the same reaction time in all periods. Universal adhesive system had slowed pain reaction time compared to conventional fluoride varnish.
Comparative Analysis Between Strip and Gels Indicated for at Home Bleaching: Analysis of Color Alteration, Roughness and Microhardness of Dental Enamel K. M. S. Aidar, L. T. A. Cintra, M. C. B. Ferreira, T. C. Fagundes, L. M. B. Esteves, et al. Journal of Esthetic and Restorative Dentistry, 2025 Purpose To compare the color alteration, surface roughness and microhardness and cross‐sectional microhardness of bovine enamel treated with at‐home whitening strips and gels. Materials and Methods Sixty‐six pigmented specimens ( n = 11) were allocated to six groups: C—cotton wool moistened with distilled water for 1 h; SDS—sodium dithionite strip, for 1 h; HPS—6.5% hydrogen peroxide strip, for 1 h; CPS—20% carbamide peroxide strip, for 1 h; HPG—7.5% hydrogen peroxide gel, for 1 h; CPG—10% carbamide peroxide gel, for 4 h. The treatments lasted 10 days, calculating the ∆E, ∆ E 00 , and ∆ W ID at baseline, 5 and 10 days, and 14 days after completion. Additional 66 polished discs ( n = 11) were used to analyze the surface roughness and microhardness of enamel before and after bleaching, cross‐sectional microhardness and integrated mineral loss (ΔZ; %Vol × μm). Data were subjected to statistical analysis by two‐way Anova RM and Tukey post‐test ( α = 0.05). Results In ∆E and ∆W ID analysis, greater values were obtained in CPG ( p < 0.001), followed by HPG and HPS ( p = 0.271). SDS and CPS ( p < 0.001) exceeded only C ( p < 0.001). In ∆ E 00 , at completion of treatments, the results were similar; however, HPG = HPS = CPS ( p = 0.237). There was an increase in roughness and decrease in surface microhardness in all bleaching groups ( p < 0.005). Concerning the cross‐sectional microhardness, the treatments were equal to C at 150 μm, the last depth analyzed. For Δ Z , the values of SDS, CPS, HPG, and CPG groups showed similar mineral loss ( p > 0.001), and the lowest value was exhibited in the Control group, followed by HPS group ( p < 0.001). Conclusion Although the strips were aesthetically effective, the CPG and HPG groups presented highest values in the ∆ E 00 and ∆ W ID analysis. However, all treatments influenced the enamel surface, increasing roughness and decreasing surface and transverse microhardness. Clinical Relevance The whitening gels promoted greater chromatic changes, but all treatments affected the enamel surface, increasing roughness and decreasing surface and transverse microhardness.
In vitro evaluation of the enhancement of glass ionomer cement features by using chitosan and nanodiamond Murilo Henrique Torres da Silva, Henrico Badaoui Strazzi-Sahyon, Renata Gallo, Ticiane Cestari Fagundes, André Luiz Fraga Briso, et al. Brazilian Dental Journal, 2025 This study investigated the influence of chitosan and nanodiamond incorporation on the surface, optical, and mechanical properties of glass ionomer cement. Total 56 samples (5 mm diameter and 2 mm thickness) were prepared and divided into 4 groups according to the incorporation of chitosan and nanodiamond on Fuji II glass ionomer cement: Control group: no incorporation; 10%CH group: incorporation of 10% chitosan; 10%ND group: incorporation of 10% of nanodiamond; 5%CH-5%ND group: incorporation of 5% chitosan and 5% nanodiamond (n=14). Analyses of color stability, surface roughness, fluorescence intensity, microhardness, morphology, and chemical composition were investigated. Additionally, water sorption, hygroscopic expansion, contact angle, surface free energy, and total free energy of interaction were also assessed. After the initial readings, the samples were individually stored in red wine solution for 28 days. Data were subjected to ANOVA followed by Tukey´s test (α=.05). Aging in wine solution altered the optical, mechanical, and surface properties of glass ionomer cement regardless of the incorporation of the compound (P<.05). 10% chitosan-incorporated glass ionomer cement promoted higher color alteration, surface roughness, and water sorption after aging (P<.05). 10% nanodiamond-incorporated glass ionomer cement showed higher microhardness compared to the other groups before aging (P<.05), however there were no differences among them after aging (P>.05). In general, no differences between the 5% chitosan- and 5% nanodiamond-incorporated glass ionomer cement and control groups were noted on the evaluated analyses (P>.05). Thus, the incorporation of 5% chitosan and 5% nanodiamond is a satisfactory alternative for maintain the surface, optical, and mechanical properties of the glass ionomer cement.
In vitro performance of violet LED and argon plasma with oxygen on dentin bleaching Karen Milaré Seicento Aidar, Lara Maria Bueno Esteves, Paulo Henrique dos Santos, Henrico Badaoui Strazzi-Sahyon, Juliana Aparecida Delben, et al. Brazilian Dental Journal, 2025 This in vitro study aimed to evaluate the effect of violet LED and argon plasma, associated or not with oxygen, on chromatic alteration, whitening index, temperature variation, wettability, surface energy, total free interaction energy, and adhesive strength in dentin tissue. Thus, 100 bovine dentin discs were allocated to 5 groups (n=20): C - control; APL - argon plasma; APL+O - argon plasma + 3% oxygen; LED - violet LED; HP - 35% hydrogen peroxide. In the first bleaching treatment for each technique, chromatic alteration (ΔE00), bleaching index (ΔWID), and temperature variation were analyzed. Subsequently, the specimens were repolished, receiving the surface treatments again and designated for contact angle (o), surface energy (γs), and total free interaction energy (ΔG) analyses (n=5). In contrast, the remaining specimens were restored for bond strength analysis (n=15). From each specimen, four beams were obtained, two evaluated immediately and two after 10,000 thermal cycles. Bond strength data were subjected to 2-way repeated measures ANOVA, and the other analyses to 1-way ANOVA with Tukey's post hoc test (α=0.05). APL+O presented bleaching efficacy similar to the HP group, which, in turn, had the lowest bond strength values (p<0.05). LED was the only treatment that generated a temperature increase and showed a hydrophobic surface. APL+O presented lower contact angle values and higher ΔG values. APL and APL+O showed bond strength values that surpassed only those of the control group. It was concluded that plasma treatments were effective in dentin bleaching; however, none of the evaluated therapies managed to prevent the loss of bond strength.
Anatomical characteristics of different tooth groups International Journal of Esthetic Dentistry, 2024
Adhesion and sealing of different universal adhesive systems associated with bulk-fill resins after using endodontic irrigation solutions: An in vitro study Érika Mayumi Omoto, Anderson Catelan, Paulo Henrique dos Santos, Luciano Tavares Angelo Cintra, Fernanda de Souza e Silva Ramos, et al. Australian Endodontic Journal, 2024 This study aimed to evaluate the interface of universal adhesive (UA) with bulk‐fill resin (BF) and dentin, after endodontic irrigation. The pulp chamber of 96 molars was irrigated with chlorhexidine 2% (CHX) or sodium hypochlorite 5.25% (NaOCl) and restored according to three restorative protocols. Microtensile bond strength (μTBS) and nanoleakage tests were performed after 24 h of thermocycling. Kruskal Wallis, Mann–Whitney and Wilcoxon were performed (p < 0.05). Comparing restorative systems, a difference was found only when irrigated with CHX after 24 h. CHX provided higher μTBS than NaOCl after 24 h for two restorative protocols; after thermocycling, NaOCl provided the greatest μTBS than CHX for one group. Decreased μTBS was observed for all restorative systems when CHX was used after thermocycling. NaOCl demonstrated the highest nanoleakage. The composition of UA influenced the immediate adhesion and sealing to BF when CHX was used; ageing has a deteriorating effect on adhesion and sealing for all restorative systems.
Fluorescence intensity of composite resin for direct veneer removal using a fluorescence-aided identification technique Giovana Maria Zeine, Érika Mayumi Omoto, Fernanda de Souza e Silva Ramos, André Luiz Fraga Briso, Paulo Henrique dos Santos, et al. Journal of Esthetic and Restorative Dentistry, 2024 ObjectivesThis laboratory study evaluated the influence of the fluorescence intensity of composite resins on additional tooth wear and the presence of restorative material in different dental thirds during the retreatment of direct veneers.Materials and MethodsThe crown dimensions of 60 bovine incisors were reduced to 10 × 8 mm. The teeth were classified according to the fluorescence intensity of the composites: low (LOW) (TPH Spectra), medium (MED) (Opallis), and high (HIGH) (Essentia) groups. The teeth were divided according to the removal methods: conventional (CON) and fluorescence‐aided identification technique (FIT). The specimens were scanned (T0), received veneer preparation, and scanned again (T1). After restorations, the composites were removed and the teeth were scanned (T2). Measurement assessments between T1 and T2 were performed to determine additional wear, presence of residual areas, and the average between additional wear and the presence of residual areas. Kruskal Wallis, Mann–Whitney, Friedman, 2‐way ANOVA, and post‐Tukey tests were performed (α < 0.05).ResultsThe comparison of composite resins indicated a smaller area of additional wear and greater residue presence in the HIGH group than the LOW group for both techniques in the cervical third. Regarding removal methods, the FIT produced greater additional wear than the CON method for the LOW and MED groups in the middle and cervical thirds. The incisal third exhibited greater additional wear than the other thirds.ConclusionsComposite resins with high fluorescence intensity removed using FIT had less tooth wear. The incisal third was the most affected area for direct veneer removal procedures.Clinical SignificanceA FIT has been proposed for composite resin removal; however, the different fluorescence intensities of composite resins can influence tooth wear caused during this procedure.
Human Pulpal Responses to Peroxides Rafael Antonio de Oliveira Ribeiro, Igor Paulino Mendes Soares, Diana Gabriela Soares, André Luiz Fraga Briso, Josimeri Hebling, et al. Tooth Whitening an Evidence Based Perspective Second Edition, 2023
Complications from the Use of Peroxides André Luiz Fraga Briso, Vanessa Rahal, Marjorie Oliveira Galinari, Lara Maria Bueno Esteves, Diana Gabriela Soares, et al. Tooth Whitening an Evidence Based Perspective Second Edition, 2023
Direct dentin bleaching: Would it be possible? Camila Ferro Clemente, Sibele de Alcântara, Lívia Maria Alves Valentim da Silva, Lara Maria Bueno Esteves, Anderson Catelan, et al. Photodiagnosis and Photodynamic Therapy, 2022
Complications from the use of peroxides André Luiz Fraga Briso, Vanessa Rahal, Marjorie Oliveira Gallinari, Diana Gabriela Soares, Carlos Alberto de Souza Costa Tooth Whitening an Evidence Based Perspective, 2016
Predation on the pointedbelly frog Leptodactylus podicipinus (Anura: Leptodactylidae) by the rufescent tiger-heron Trigrisoma lineatum (Pelecaniformes: Ardeidae) Herpetology Notes, 2014
Clinical evaluation of a composite resin and a resin-modified glass-ionomer cement in non-carious cervical lesions: One-year results International Journal of Clinical Dentistry, 2012
Clinical Evaluation of the effectiveness of different bleaching therapies in vital teeth International Journal of Periodontics and Restorative Dentistry, 2012
Correlation between hybrid layer thickness, resin tag length and microtensile bond strength of a self-etching adhesive system. Acta Odontologica Latinoamericana AOL, 2012
Occurrence of sensitivity during at-home and in-office tooth bleaching therapies with or without use of light sources. Acta Odontologica Latinoamericana AOL, 2012
Twenty years experience with pit and fissure sealants Perspectives on Clinical Dentistry, 2011
Direct restorative treatment of dental erosion caused by gastroesophageal reflux disease associated with bruxism: a case report. Compendium of Continuing Education in Dentistry Jamesburg N J 1995, 2011
Influence of the hybrid layer thickness and resin tag length on microtensile bond strength. Acta Odontologica Latinoamericana AOL, 2011
Smile restoration through use of enamel microabrasion associated with tooth bleaching. Compendium of Continuing Education in Dentistry Jamesburg N J 1995, 2011
