N-Acetylcysteine Reduces Alveolar Bone Loss and Mitigates Systemic Oxidative Damage in Rats With Apical Periodontitis Ian Wesley Rocha dos Santos, Deiweson Souza‐Monteiro, Deborah Ribeiro Frazão, Zuleni Alexandre Lisboa da Silva, João Daniel Mendonça de Moura, Jorddy Neves Cruz, Fabrício Mezzomo Collares, Renata Duarte de Souza‐Rodrigues, Luciano Tavares Ângelo Cintra, Rafael Rodrigues Lima International Endodontic Journal, 2026 Aim This study aimed to evaluate the effects of N‐acetylcysteine (NAC) supplementation in apical periodontitis (AP) induced in rats. Methodology Eighteen male Wistar rats were randomly assigned to three groups: control, AP, and AP plus NAC. NAC was administered by oral gavage (100 mg/kg/day), beginning 1 day after lesion induction and continued daily until the day preceding euthanasia. AP induction was performed by exposing the dental pulp of the lower first molars bilaterally, maintaining this condition for 28 days. After this period, the animals were euthanized, and the following biological materials were collected: blood (for systemic oxidative stress analysis) and hemimandibles for histopathological and histochemical, and micro‐computed tomography analyses, aiming to measure bone quality parameters and periapical volume. Statistical analyses were performed using one‐way ANOVA and Tukey's post hoc test. In addition, correlation analyses and multivariate analyses of variance (MANOVA) were performed on the biochemical parameters. Results The study results showed that animals supplemented with NAC had greater preservation of bone quality parameters and a reduction in periapical volume progression when compared to the only apical periodontitis group. Additionally, in the analysis of systemic oxidative stress, supplemented animals showed higher antioxidant parameter levels and lower oxidant levels compared to non‐supplemented animals, which also showed reduced preservation of bone collagen content. Conclusions The study findings suggest that NAC supplementation promoted greater preservation of bone quality, reduced periapical volume development, and modulation of endogenous antioxidant and oxidant aspects. This indicates that NAC can decrease local and systemic damage caused by AP, highlighting its potential as an adjunctive agent in processes involving systemic oxidative stress and the preservation of biological structures.
Integrative Computational and Experimental Approaches Reveal the Protective Role of Moderate Caffeine Intake Against Apical Periodontitis Induced Bone Loss Matheus Ferreira Lima Rodrigues, Deborah Ribeiro Frazão, Deiweson Souza‐Monteiro, Vinicius Ruan Neves dos Santos, Felipe Oliveira Nunes, João Daniel Mendonça de Moura, Thamires Campos Gomes, Jorddy Neves Cruz, Cristiane do Socorro Ferraz Maia, Rodrigo A. Cunha, Fabrício Mezzomo Collares, Rogerio de Castilho Jacinto, Rafael Rodrigues Lima International Endodontic Journal, 2026 Aim To investigate whether moderate systemic caffeine intake modulates the progression of apical periodontitis (AP) and associated alveolar bone loss, combining in vivo rat experiments with in silico molecular docking to explore potential mechanisms. Methodology Male Wistar rats were randomly assigned to four groups ( n = 8 per group): control, caffeine, AP, AP + caffeine. AP was induced by pulp exposure of mandibular first molars and allowed to develop for 28 days. Animals in caffeine groups received 10 mg/kg/day by orogastric gavage during the experimental period. The antioxidant capacity of caffeine was assessed by DPPH• and ABTS• + assays. Systemic oxidative status was evaluated by blood reduced glutathione (GSH) and thiobarbituric acid reactive substances (TBARS). Histology, Picro‐Sirius red staining for collagen, and micro‐computed tomography (micro‐CT) analysis of alveolar bone (BV/TV, Tb.N, Tb.Sp, porosity, lesion volume) were performed. Molecular docking against adenosine A 1 and A 2 A receptors was used to probe caffeine–receptor interactions. Results Caffeine showed relevant radical‐scavenging activity in vitro (DPPH• assay). AP induced systemic redox imbalance, marked inflammatory infiltration, collagen loss and increased lesion volume. Moderate caffeine intake restored redox markers (↑GSH, ↓TBARS), attenuated inflammatory infiltrate, preserved collagen content and reduced lesion volume (AP + caffeine vs. AP; p < 0.05). Micro‐CT demonstrated improved alveolar bone microarchitecture in AP + caffeine group (increased BV/TV and Tb.N; reduced Tb.Sp and porosity). Molecular docking indicated stable hydrophobic and hydrogen‐bond interactions of caffeine within A 1 and A 2 A receptor binding pockets, supporting an antagonistic effect on adenosine signalling consistent with reduced pro‐inflammatory activation. Conclusion Moderate systemic caffeine (10 mg/kg/day) attenuates apical periodontitis progression and preserves alveolar bone quality in rats, associated with antioxidant activity and a probable modulation of adenosine receptor‐mediated inflammatory pathways.
Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats Rayssa Maitê Farias Nazário, Deborah Ribeiro Frazão, Leonardo Oliveira Bittencourt, Victoria Santos Chemelo, José Mário Matos‐Sousa, Beatriz Rodrigues Risuenho Peinado, Roberta Souza D’almeida Couto, Osmar Alves Lameira, João Daniel Mendonça de Moura, Jorddy Neves Cruz, Fabrício Mezzomo Collares, Rafael Rodrigues Lima International Endodontic Journal, 2026 Aim This study aimed to investigate the effects of copaiba oil–resin on induced apical periodontitis in rats. Methodology A total of 24 male Wistar rats were divided equally into three groups (eight animals each): control (C), apical periodontitis (AP) and apical periodontitis with copaiba administration (AP + COP). The AP was induced by exposing the pulp chambers of the mandibular first molars to the oral environment. The openings were maintained for 28 days to allow lesion development. The AP + COP group received systemic administration of 200 mg/kg of copaiba oil–resin via intragastric gavage during the final 7 days of the AP induction period. The rats were then euthanised, and their hemimandibles were subjected to histopathological analysis to assess tissue preservation, histochemical staining with picrosirius red to evaluate collagen content, and microcomputed tomography to assess lesion volume and bone quality parameters. Statistical analyses were performed using a one‐way ANOVA, followed by Tukey's post hoc test for parametric data and the Kruskal–Wallis test for nonparametric data. The results are expressed as mean and standard error of the mean for parametric tests, and median and interquartile deviation for the nonparametric test. Results The findings showed that copaiba oil–resin reduced lesion volume compared to the untreated group ( p = 0.0261), as well as reducing the space between the bone trabeculae found in the AP group ( p = 0.0063). Additionally, copaiba oil–resin preserved the collagen fibres, which were more degraded in the untreated group ( p = 0.0009). Histopathological analysis showed that copaiba oil–resin reduced tissue damage, preserving a significant area of alveolar bone surrounding the lesion. Conclusions These results indicate that copaiba oil resin has a promising adjunct therapeutic potential to reduce the bone loss caused by apical periodontitis and contribute to the maintenance of quality in the remaining bone.
Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis João Daniel Mendonça de Moura, Vinicius Ruan Neves Dos Santos, Leonardo Oliveira Bittencourt, Fabrício Mezzomo Collares, Paulo Fernando Santos Mendes, José Mario Matos‐Sousa, Beatriz Rodrigues Risuenho Penaido, José Messias Perdigão, Herve Rogez, Rafael Rodrigues Lima, Patricia de Almeida Rodrigues International Endodontic Journal, 2025 AimThis study aimed to investigate the effects of açai on bone and systemic damage caused by apical periodontitis (AP) in an animal model.MethodologyIn this experimental study, 32 male Wistar rats were randomly allocated into six groups—Control 14 days (n = 4), Control 28 days (n = 4), AP 14 days (n = 4), AP 28 days (n = 4), AP plus açai treatment for 14 days (n = 8) and AP plus açai treatment for 28 days (n = 8). Apical periodontitis was induced under general anaesthesia by exposing the pulp of the first molars to the oral environment. Daily treatments were administered by gavage at a dose of 0.01 mL/g, using either saline solution or clarified açai. At the end of each experimental period, periapical lesions were quantitatively evaluated by micro‐computed tomography (micro‐CT) and histopathological analyses, whilst systemic oxidative stress was assessed through biochemical assays. Data normality was verified using the Shapiro–Wilk test, followed by one‐way anova and Tukey's post hoc test (p < .05).ResultsMicro‐CT analysis revealed that açai reduced apical periodontitis lesion volume and improved bone quality (p < .05). Histopathological evaluation corroborated these findings, revealing moderate inflammation at 14 days and more pronounced, heterogeneous inflammatory responses at 28 days, with no significant differences between groups. Additionally, açai modulated systemic oxidative biochemistry, enhanced antioxidant defences and reduced pro‐oxidant damage after 28 days.ConclusionsOral açai administration was associated with reduced progression of apical periodontitis and improved bone quality, suggesting its potential as a protective antioxidant in endodontic treatment, minimizing both local and systemic damage.
Physical training attenuates systemic cytokine response and tissue damage triggered by apical periodontitis Railson de Oliveira Ferreira, Matheus Soares Pereira, Deiweson Souza-Monteiro, Deborah Ribeiro Frazão, João Daniel Mendonça de Moura, Daiane Claydes Baia-da-Silva, Leonardo Oliveira Bittencourt, Gabriela de Souza Balbinot, Fabrício Mezzomo Collares, Maria Laura de Souza Lima, Aurigena Antunes de Araújo, Rafael Rodrigues Lima Scientific Reports, 2024 Apical periodontitis (AP) is a condition characterized by inflammatory and infectious components in the tooth canal. AP affects periradicular tissues and has systemic repercussions. Physical exercise is a structured activity that requires cardiorespiratory function, and can modulate the inflammatory profile in pathological conditions. As a result, this study aimed to determine the effects of aerobic physical training (PT) on the alveolar bone with and without AP, and its systemic inflammatory repercussions. AP was induced in the mandibular first molars, and PT was performed on a treadmill for five consecutive days over four weeks, with progressive increases in speed and activity time. Blood samples were collected to determine serum cytokine levels using immunoassays, and alveolar bone samples were collected for histopathological evaluation, lesion volume and microarchitecture assessment using computed microtomography. Animals with AP had increased pro-inflammatory cytokines levels compared to those without AP; however, these levels were attenuated or restored by PT. Compared to the AP group, the AP + PT group had a smaller lesion volume and greater preservation of the bone trabeculae in the remaining alveolar bone surrounding the lesion. In overall, PT minimized the severity of AP proving to be a valid strategy for individuals undergoing endodontic treatment.
Açai (Euterpe oleracea Mart.) supplementation promotes histological and ultrastructural changes in rats' alveolar bone João Daniel Mendonça de Moura, Patricia de Almeida Rodrigues, Vinicius Ruan Neves Dos Santos, Leonardo Oliveira Bittencourt, José Mario Matos-Sousa, Beatriz Rodrgiues Risuenho Peinado, José Messias Perdigão, Herve Rogez, Fabrício Mezzomo Collares, Rafael Rodrigues Lima Heliyon, 2024 The açai juice contains high concentrations of phenolic compounds, including cyanidin-3-glucoside and others flavonoids. The aim of this study was to evaluate the impact of açai supplementation on healthy mandibular alveolar bone in male albino rats of the Wistar strain. 24 rats were divided into 3 groups, in which one group received a daily dose of saline solution and the other two groups were treated with daily doses of clarified açai juice for 14 or 28 days. After the experiment, hemimandibles were collected and analyzed using Scanning Electron Microscopy (SEM), histological assessments, and micro-CT. Results showed changes in the integrity of the alveolar bone as seen in SEM, increased osteocyte density and higher collagen matrix area in the açai group compared to the control group as seen in histological analysis, and increased bone volume, trabecular thickness and number, and cortical bone as seen in micro-CT analysis. The space between bone trabeculae showed no difference among the groups. These results suggest that açai supplementation may have a structural change effect on alveolar bone, but further research is needed to confirm these findings in humans and to determine the exact mechanisms behind these effects.
Is there any association between the presence of biomarkers and apical periodontitis? A systematic review José Mário Matos-Sousa, Victória Santos Chemelo, Deborah Ribeiro Frazão, Leonardo Oliveira Bittencourt, João Daniel Mendonça de Moura, Caio Melo Mesquita, Guido Marañón-Vásquez, Nathalia Carolina Fernandes Fagundes, Luiz Renato Paranhos, Lucianne Cople Maia, Marta Chagas Monteiro, Rafael Rodrigues Lima Frontiers in Immunology, 2024 This systematic review aimed to verify whether there is evidence of an association between apical periodontitis and the presence of systemic biomarkers. This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses - PRISMA. For this, the acronym PECO was used; population (P) of adult humans exposed (E) to the presence of apical periodontitis, compared (C) to adult humans without apical periodontitis, and the outcome (O) of the presence of biomarkers was observed. The articles were searched in PubMed, Scopus, Web of Science, LILACS, Cochrane Library, OpenGray, and Google Scholar grey databases. Subsequently, studies were excluded based on title, abstract, and full article reading, following the eligibility criteria. The methodological quality of the selected studies was evaluated using the Newcastle-Ottawa qualifier. After exclusion, 656 studies were identified, resulting in 17 final articles that were divided into case-control, cross-sectional, and cohort studies. Eight studies were considered to have a low risk of bias, one had a medium risk of bias, and eight had a high risk of bias. In addition, 12 articles evaluated biomarkers in blood plasma, four evaluated them in saliva, and only one evaluated them in gingival crevicular fluid. The results of these studies indicated an association between apical periodontitis and the systemic presence of biomarkers. These markers are mainly related to inflammation, such as interleukins IL-1, IL-2, and IL-6, oxidative markers, such as nitric oxide and superoxide anions, and immunoglobulins IgG and IgM.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier (CRD42023493959).
Modulation of blood redox status by the progression of induced apical periodontitis in rats Deborah Ribeiro Frazão, Paulo Fernando Santos Mendes, Daiane Claydes Baia-da-Silva, João Daniel Mendonça de Moura, Vinicius Ruan Neves dos Santos, José Mario Matos-Sousa, Gabriela de Souza Balbinot, Douglas Magno Guimarães, Fabrício Mezzomo Collares, Rafael Rodrigues Lima Frontiers in Physiology, 2023
Biological Activity of Copaiba in Damage to the Alveolar Bone in a Model of Periodontitis Induced in Rats Vinicius Ruan Neves dos Santos, João Victor da Silva Motta, Deborah Ribeiro Frazão, Railson de Oliveira Ferreira, Deiweson Souza-Monteiro, Daiane Claydes Baia-da-Silva, Paulo Fernando Santos Mendes, Leonardo Oliveira Bittencourt, João Daniel Mendonça de Moura, Osmar Alves Lameira, Gabriela de Souza Balbinot, Fabrício Mezzomo Collares, Cassiano Kuchenbecker Rösing, Rafael Rodrigues Lima Molecules, 2022
Açaí (Euterpe oleracea Mart.) Attenuates Oxidative Stress and Alveolar Bone Damage in Experimental Periodontitis in Rats Vinicius Ruan Neves dos Santos, Deborah Ribeiro Frazão, Railson de Oliveira Ferreira, Paulo Fernando Santos Mendes, Daiane Claydes Baia-da-Silva, Deiweson Souza-Monteiro, Leonardo Oliveira Bittencourt, João Daniel Mendonça de Moura, José Messias Perdigão, Bruno José Brito Teixeira, Everton Luiz Pompeu Varela, Gabriela de Souza Balbinot, Sandro Percário, Herve Rogez, Cassiano Kuchenbecker Rösing, Fabrício Mezzomo Collares, Rafael Rodrigues Lima Antioxidants, 2022
Copaiba Oil–Resin Reduces the Alveolar Bone Damage Triggered by Apical Periodontitis in Rats RMF Nazário, DR Frazão, LO Bittencourt, VS Chemelo, JM Matos‐Sousa, ... International Endodontic Journal 59 (3), 511-523 , 2026 2026
REGENERATIVE ENDODONTIC PROCEDURES: MAPPING AND CRITICAL APPRAISAL OF CLINICAL TRIAL EVIDENCE FO Nunes, EB Sollim, CF Dos Santos, MKM Ferreira, JDM Moura, ... Journal of Endodontics , 2026 2026 Citations: 2
Evaluating Large Language Models performance in Endodontics: A clinical experimental study PRZ de Almeida, IA Barbosa, MSA Alves, SAF de Menezes, ... Research, Society and Development 15 (1), e2515150523-e2515150523 , 2026 2026
Integrative Computational and Experimental Approaches Reveal the Protective Role of Moderate Caffeine Intake Against Apical Periodontitis Induced Bone Loss MFL Rodrigues, DR Frazão, D Souza‐Monteiro, VRN Dos Santos, ... International Endodontic Journal , 2026 2026
N‐Acetylcysteine Reduces Alveolar Bone Loss and Mitigates Systemic Oxidative Damage in Rats With Apical Periodontitis IWR Dos Santos, D Souza‐Monteiro, DR Frazão, ZAL da Silva, ... International Endodontic Journal , 2026 2026
REVISÃO DE NOVE PLANTAS MEDICINAIS DA LISTA RENISUS COM POTENCIAL USO EM ODONTOLOGIA NM de Souza Lopes, P de Almeida Rodrigues, JDM de Moura, ... ARACÊ 7 (11), e9966-e9966 , 2025 2025
Assessing the diagnostic and treatment accuracy of Large Language Models (LLMs) in Peri-Implant Diseases: a clinical experimental study IA Barbosa, MSA Alves, PRZ de Almeida, P de Almeida Rodrigues, ... Journal of Dentistry, 106091 , 2025 2025 Citations: 3
Is Artificial Intelligence an Underutilized Tool for Assisting Diagnosis in Dentistry? JD Mendonça de Moura, RR de Souza Fonseca, ... International journal of odontostomatology 19 (3), 193-194 , 2025 2025
Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis JDM de Moura, VRND Santos, LO Bittencourt, FM Collares, PFS Mendes, ... International Endodontic Journal , 2025 2025 Citations: 6
Comparative accuracy of artificial intelligence chatbots in pulpal and periradicular diagnosis: A cross-sectional study JDM de Moura, CE Fontana, VHR da Silva Lima, I de Souza Alves, ... Computers in Biology and Medicine 183, 109332 , 2024 2024 Citations: 28
High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats JM Matos-Sousa, D Souza-Monteiro, VRN Dos Santos, MKM Ferreira, ... Heliyon 10 (22) , 2024 2024 Citations: 7
Comparative analysis of debris extrusion and instrumentation time among various endodontic file systems: an in vitro study: Debris Extrusion and Instrumentation … CE Fontana, B dos Santos Ribeiro, L de Carvalho Davanso, ... Giornale Italiano di Endodonzia 38 (3) , 2024 2024 Citations: 6
Is there any association between the presence of biomarkers and apical periodontitis? A systematic review JM Matos-Sousa, VS Chemelo, DR Frazão, LO Bittencourt, JDM Moura, ... Frontiers in Immunology 15, 1366954 , 2024 2024 Citations: 17
Açai (Euterpe oleracea Mart.) supplementation promotes histological and ultrastructural changes in rats' alveolar bone JDM de Moura, P de Almeida Rodrigues, VRN Dos Santos, LO Bittencourt, ... Heliyon , 2024 2024 Citations: 2
Physical training attenuates systemic cytokine response and tissue damage triggered by apical periodontitis RO Ferreira, MS Pereira, D Souza-Monteiro, DR Frazão, JDM de Moura, ... Scientific Reports 14 (1), 8030 , 2024 2024 Citations: 5
Restorative challenges and successful outcome of apexification and revascularization in adjacent traumatized immature teeth JDM de Moura, ARL dos Santos Miranda, NR Da Silva, MF Lobato, ... Giornale Italiano di Endodonzia , 2024 2024 Citations: 1
Evaluation of the apical sealing of an eggshell hydroxyapatite-based sealer CE Fontana, BA Dos Santos, VC da Silva, SL Pinheiro Journal of Clinical and Experimental Dentistry 15 (11), e895 , 2023 2023 Citations: 7
Setting time of calcium silicate-based sealers at different acidic pHs CG Teixeira, MAM da Silva, ACP Janini, JDM de Moura, DGP Rocha, ... Giornale Italiano di Endodonzia 37 (2) , 2023 2023 Citations: 2
Modulation of blood redox status by the progression of induced apical periodontitis in rats DR Frazão, PF Santos Mendes, DC Baia-da-Silva, ... Frontiers in Physiology 14, 1214990 , 2023 2023 Citations: 14
A laboratory study analysis of the cyclic fatigue strength of glide path instruments at simulated body temperature CE Fontana, L Bonfante, YM Rosa, JDM de Moura, RA Pelegrine, ... Giornale Italiano di Endodonzia 36 (2) , 2022 2022
MOST CITED SCHOLAR PUBLICATIONS
Extrusion of debris from curved root canals instrumented up to different working lengths using different reciprocating systems JDM de Moura, CE da Silveira Bueno, CE Fontana, RA Pelegrine Journal of endodontics 45 (7), 930-934 , 2019 2019.0 Citations: 42
Comparative accuracy of artificial intelligence chatbots in pulpal and periradicular diagnosis: A cross-sectional study JDM de Moura, CE Fontana, VHR da Silva Lima, I de Souza Alves, ... Computers in Biology and Medicine 183, 109332 , 2024 2024.0 Citations: 28
Açaí ( Euterpe oleracea Mart.) Attenuates Oxidative Stress and Alveolar Bone Damage in Experimental Periodontitis in Rats VRN Dos Santos, DR Frazão, RO Ferreira, PFS Mendes, ... Antioxidants 11 (10), 1902 , 2022 2022.0 Citations: 20
Is there any association between the presence of biomarkers and apical periodontitis? A systematic review JM Matos-Sousa, VS Chemelo, DR Frazão, LO Bittencourt, JDM Moura, ... Frontiers in Immunology 15, 1366954 , 2024 2024.0 Citations: 17
Modulation of blood redox status by the progression of induced apical periodontitis in rats DR Frazão, PF Santos Mendes, DC Baia-da-Silva, ... Frontiers in Physiology 14, 1214990 , 2023 2023.0 Citations: 14
Biological Activity of Copaiba in Damage to the Alveolar Bone in a Model of Periodontitis Induced in Rats VRN Dos Santos, JVS Motta, DR Frazão, RO Ferreira, D Souza-Monteiro, ... Molecules 27 (19), 6255 , 2022 2022.0 Citations: 11
Influence of conservative endodontic access cavities on instrumentation of oval‐shaped straight root canals ARL dos Santos Miranda, JDM de Moura, PHS Calefi, PA Amoroso Silva, ... International Endodontic Journal 55 (1), 103-112 , 2022 2022.0 Citations: 9
The impact of kinematics, single-file technique and preparation time on the apical extrusion of debris CE Fontana, GM Ferraresso, LP Derigi, JDM de Moura, RA Pelegrine, ... Giornale Italiano di Endodonzia 34 (2) , 2020 2020.0 Citations: 9
High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats JM Matos-Sousa, D Souza-Monteiro, VRN Dos Santos, MKM Ferreira, ... Heliyon 10 (22) , 2024 2024.0 Citations: 7
Evaluation of the apical sealing of an eggshell hydroxyapatite-based sealer CE Fontana, BA Dos Santos, VC da Silva, SL Pinheiro Journal of Clinical and Experimental Dentistry 15 (11), e895 , 2023 2023.0 Citations: 7
Evaluation of alveolar bone preservation and oxidative stress reduction with açai in Wistar rats with induced apical periodontitis JDM de Moura, VRND Santos, LO Bittencourt, FM Collares, PFS Mendes, ... International Endodontic Journal , 2025 2025.0 Citations: 6
Comparative analysis of debris extrusion and instrumentation time among various endodontic file systems: an in vitro study: Debris Extrusion and Instrumentation … CE Fontana, B dos Santos Ribeiro, L de Carvalho Davanso, ... Giornale Italiano di Endodonzia 38 (3) , 2024 2024.0 Citations: 6
Physical training attenuates systemic cytokine response and tissue damage triggered by apical periodontitis RO Ferreira, MS Pereira, D Souza-Monteiro, DR Frazão, JDM de Moura, ... Scientific Reports 14 (1), 8030 , 2024 2024.0 Citations: 5
Anatomical proximity of upper teeth and local factors associated with the thickness of the maxillary sinus membrane: a retrospective study P de Almeida Rodrigues, VV Pinheiro, JDM de Moura, DCB da Silva, ... Giornale Italiano di Endodonzia 35 (2) , 2021 2021.0 Citations: 4
Assessing the diagnostic and treatment accuracy of Large Language Models (LLMs) in Peri-Implant Diseases: a clinical experimental study IA Barbosa, MSA Alves, PRZ de Almeida, P de Almeida Rodrigues, ... Journal of Dentistry, 106091 , 2025 2025.0 Citations: 3
Analysis of the influence of different kinematic instrumentation in extrusion of apical debris CE Fontana, GM Ferraresso, L Pinheiro, GRBP Derigi, VC Trevensoli, ... Citations: 3
REGENERATIVE ENDODONTIC PROCEDURES: MAPPING AND CRITICAL APPRAISAL OF CLINICAL TRIAL EVIDENCE FO Nunes, EB Sollim, CF Dos Santos, MKM Ferreira, JDM Moura, ... Journal of Endodontics , 2026 2026.0 Citations: 2
Açai (Euterpe oleracea Mart.) supplementation promotes histological and ultrastructural changes in rats' alveolar bone JDM de Moura, P de Almeida Rodrigues, VRN Dos Santos, LO Bittencourt, ... Heliyon , 2024 2024.0 Citations: 2
Setting time of calcium silicate-based sealers at different acidic pHs CG Teixeira, MAM da Silva, ACP Janini, JDM de Moura, DGP Rocha, ... Giornale Italiano di Endodonzia 37 (2) , 2023 2023.0 Citations: 2
Restorative challenges and successful outcome of apexification and revascularization in adjacent traumatized immature teeth JDM de Moura, ARL dos Santos Miranda, NR Da Silva, MF Lobato, ... Giornale Italiano di Endodonzia , 2024 2024.0 Citations: 1