Carlos Alberto Leite Filho

@fm.usp.br

Post-Doctoral Researcher at the Department of Physiotherapy, Speech-Language-Hearing Sciences, and Occupational Therapy of the School of Medicine, University of São Paulo
Universidade de São Paulo

Carlos Alberto Leite Filho

RESEARCH, TEACHING, or OTHER INTERESTS

Speech and Hearing, Cognitive Neuroscience, Neuropsychology and Physiological Psychology
6

Scopus Publications

52

Scholar Citations

4

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Click Ordering Lateralization Test: Applicability and feasibility of a new paradigm for assessing sound lateralization behavior
    Elizabeth Della Colette, Carlos Alberto Leite Filho, Camila Maia Rabelo, Frank Musiek, Eliane Schochat
    International Journal of Pediatric Otorhinolaryngology, 2025
  • Cross-cultural adaptation and validation evidence of the Hand-Foot Syndrome 14 (HFS-14) instrument
    Veronica Paula Torel de Moura, Carlos Alberto Leite Filho, Thais Scarpelli, Edvane Birelo Lopes De Domenico
    Acta Paulista De Enfermagem, 2025
    Objective To cross-culturally adapt the Brazilian version of the Hand-Foot Syndrome 14 (HFS-14) instrument to Brazilian Portuguese and obtain evidence of construct validity. Methods Methodological, quantitative study divided into two stages. Stage 1: cross-cultural adaptation, which consisted of translating the instrument from English into Portuguese, and back into English, and cross-cultural validation of the instrument in Portuguese, through content validity analysis and assessment by the target population. Stage 2: obtaining evidence of construct validity by applying the questionnaire to a sample of 110 participants undergoing therapy with drugs that potentially cause hand-foot syndrome. Evidence of validity was investigated using exploratory and confirmatory factor analysis techniques, item response theory parameterization, and relationships with the Skindex-16 instrument. Results The Brazilian Portuguese version of the HFS-14 showed excellent cross-cultural validity with an overall Content Validity Index of 0.92 and 100% acceptability by the target population. The instrument presented a unifactorial structure with factor loadings ≥ 0.516 for all items in both analyzes and good internal consistency and model fit indices. Correlation coefficients with the Skindex-16 ranging from 0.477 to 0.589 showed an association between the constructs measured by each instrument. Conclusion This study provides evidence of validity for the Brazilian version of the HFS-14 as an instrument capable of assisting in the assessment of the quality of life of patients with hand-foot syndrome.
  • Auditory temporal resolution and backward masking in musicians with absolute pitch
    Carlos Alberto Leite Filho, Caroline Nunes Rocha-Muniz, Liliane Desgualdo Pereira, Eliane Schochat
    Frontiers in Neuroscience, 2023
    Among the many questions regarding the ability to effortlessly name musical notes without a reference, also known as absolute pitch, the neural processes by which this phenomenon operates are still a matter of debate. Although a perceptual subprocess is currently accepted by the literature, the participation of some aspects of auditory processing still needs to be determined. We conducted two experiments to investigate the relationship between absolute pitch and two aspects of auditory temporal processing, namely temporal resolution and backward masking. In the first experiment, musicians were organized into two groups according to the presence of absolute pitch, as determined by a pitch identification test, and compared regarding their performance in the Gaps-in-Noise test, a gap detection task for assessing temporal resolution. Despite the lack of statistically significant difference between the groups, the Gaps-in-Noise test measures were significant predictors of the measures for pitch naming precision, even after controlling for possible confounding variables. In the second experiment, another two groups of musicians with and without absolute pitch were submitted to the backward masking test, with no difference between the groups and no correlation between backward masking and absolute pitch measures. The results from both experiments suggest that only part of temporal processing is involved in absolute pitch, indicating that not all aspects of auditory perception are related to the perceptual subprocess. Possible explanations for these findings include the notable overlap of brain areas involved in both temporal resolution and absolute pitch, which is not present in the case of backward masking, and the relevance of temporal resolution to analyze the temporal fine structure of sound in pitch perception.
  • A Study on the Reference Values and Cutoff Criteria of Masking Level Difference for Children Aged 7–12 Years
    Carlos Alberto Leite Filho, Mônica de Oliveira Viana, Fátima Cristina Alves Branco-Barreiro, Silvana Maria Monte Coelho Frota
    Journal of Clinical Medicine, 2022
    The Masking Level Difference (MLD) test is one of the main instruments for investigating binaural interaction. Studies with children aged 7–12 years still disagree about the influence of age on test performance and present discordant reference values. This study aimed to verify the effect of age on the performance of children aged 7–12 years in the MLD test and to establish reference values and cutoff criteria for this age group. Fifty-nine children with normal hearing were organized in three groups according to their age: 7–8 (n = 20), 9–10 (n = 20), and 11–12 (n = 19) years. The participants completed the MLD test by Auditec®. The Kruskal–Wallis statistical test was used to compare groups. Reference values were obtained by calculating mean, standard deviation, median, mode, and percentiles, while the cutoff criterion was obtained by subtracting two standard deviations from the mean. No statistically significant differences were observed between the groups regarding the MLD test measures. The mean MLD was 10.51 ± 1.84 dB and the cutoff point was set at 7 dB. Thus, reference values for the MLD test were established for children aged 7–12 years, who presented no effect of age on test performance.
  • Evidence of Validity and Normative Values of a New Auditory Backward Masking Test
    Renata Filippini, Carlos Alberto Leite Filho, Gabriela Melo Santos Bonassa Barros, Frank E. Musiek, Eliane Schochat
    Journal of Clinical Medicine, 2022
    There are still no valid, clinically feasible instruments to assess backward masking (BM), an auditory temporal processing (ATP) phenomenon. The aim of this study was to develop, standardize and present evidence of validity for a behavioral test for BM assessment. Young adults were submitted to a BM test (BMT), where they were asked to identify a 1000 Hz pure tone followed by a narrowband noise with interstimulus intervals of 0 to 400 ms and signal-to-noise ratio (SNR) between −20 and −30 dB. The correct response rate and target sound detection threshold were calculated, and the results compared with those of young adults with abnormal ATP tests and older adults. Diagnostic accuracy analyses were carried out. Young adults with normal ATP obtained an average correct response rate of 89 and 87% for SNR −20 and −30 dB, respectively, with average thresholds between 10 and 15 ms and no difference between the left and right ears. Results were more consistent at SNR −20 dB, and the best diagnostic accuracy was obtained for SNR −20 dB, with good specificity, but low sensitivity. Normative values were obtained for the BMT, which proved to be clinically feasible, with preliminary evidence of validity.
  • Auditory behavior and auditory temporal resolution in children with sleep-disordered breathing
    Carlos Alberto Leite Filho, Fábio Ferreira da Silva, Márcia Pradella-Hallinan, Sandra Doria Xavier, Mônica Carolina Miranda, Liliane Desgualdo Pereira
    Sleep Medicine, 2017

RECENT SCHOLAR PUBLICATIONS

  • Cross-cultural adaptation and validation evidence of the Hand-Foot Syndrome 14 (HFS-14) instrument
    VPT Moura, CA Leite Filho, T Scarpelli, EBLD Domenico
    Acta Paul Enferm 38, - , 2025
    2025
  • Click Ordering Lateralization Test: Applicability and feasibility of a new paradigm for assessing sound lateralization behavior
    E Della Colette, CA Leite Filho, CM Rabelo, F Musiek, E Schochat
    International Journal of Pediatric Otorhinolaryngology 189, 112215 , 2025
    2025
  • Validação do teste de mascaramento temporal sucessor e investigação do processamento temporal de músicos com ouvido absoluto
    CA Leite Filho, E Schochat
    2024
  • Auditory temporal resolution and backward masking in musicians with absolute pitch
    CA Leite Filho, CN Rocha-Muniz, LD Pereira, E Schochat
    Frontiers in Neuroscience 17, 1151776 , 2023
    2023
    Citations: 3
  • A study on the reference values and cutoff criteria of masking level difference for children aged 7–12 years
    CA Leite Filho, M de Oliveira Viana, FCA Branco-Barreiro, SMMC Frota
    Journal of Clinical Medicine 11 (18), 5282 , 2022
    2022
    Citations: 4
  • Evidence of Validity and Normative Values of a New Auditory Backward Masking Test
    R Filippini, CA Leite Filho, GMSB Barros, FE Musiek, E Schochat
    Journal of Clinical Medicine 11 (17), 4933 , 2022
    2022
    Citations: 6
  • Masking Level Difference: test-retest reliability assessment in normal hearing female university students
    SMMC Frota, CA Leite Filho, CS Bruno, LB Carvalho, NA Riegel, ...
    CoDAS 34, e20200207 , 2022
    2022
    Citations: 6
  • Considerations on linear correlation analysis
    CA Leite Filho
    Audiology-Communication Research 24 , 2019
    2019
    Citations: 1
  • Auditory behavior and auditory temporal resolution in children with sleep-disordered breathing
    CA Leite Filho, FF da Silva, M Pradella-Hallinan, SD Xavier, MC Miranda, ...
    Sleep Medicine 34, 90-95 , 2017
    2017
    Citations: 20
  • Hearing loss in children exposed to toxoplasmosis during their gestation
    CA Leite Filho, LCC Lagreca, NO Jesus, CP Corvaro, MAG Ferrarini, ...
    Revista CEFAC 19, 330-339 , 2017
    2017
    Citations: 12

MOST CITED SCHOLAR PUBLICATIONS

  • Auditory behavior and auditory temporal resolution in children with sleep-disordered breathing
    CA Leite Filho, FF da Silva, M Pradella-Hallinan, SD Xavier, MC Miranda, ...
    Sleep Medicine 34, 90-95 , 2017
    2017
    Citations: 20
  • Hearing loss in children exposed to toxoplasmosis during their gestation
    CA Leite Filho, LCC Lagreca, NO Jesus, CP Corvaro, MAG Ferrarini, ...
    Revista CEFAC 19, 330-339 , 2017
    2017
    Citations: 12
  • Evidence of Validity and Normative Values of a New Auditory Backward Masking Test
    R Filippini, CA Leite Filho, GMSB Barros, FE Musiek, E Schochat
    Journal of Clinical Medicine 11 (17), 4933 , 2022
    2022
    Citations: 6
  • Masking Level Difference: test-retest reliability assessment in normal hearing female university students
    SMMC Frota, CA Leite Filho, CS Bruno, LB Carvalho, NA Riegel, ...
    CoDAS 34, e20200207 , 2022
    2022
    Citations: 6
  • A study on the reference values and cutoff criteria of masking level difference for children aged 7–12 years
    CA Leite Filho, M de Oliveira Viana, FCA Branco-Barreiro, SMMC Frota
    Journal of Clinical Medicine 11 (18), 5282 , 2022
    2022
    Citations: 4
  • Auditory temporal resolution and backward masking in musicians with absolute pitch
    CA Leite Filho, CN Rocha-Muniz, LD Pereira, E Schochat
    Frontiers in Neuroscience 17, 1151776 , 2023
    2023
    Citations: 3
  • Considerations on linear correlation analysis
    CA Leite Filho
    Audiology-Communication Research 24 , 2019
    2019
    Citations: 1
  • Cross-cultural adaptation and validation evidence of the Hand-Foot Syndrome 14 (HFS-14) instrument
    VPT Moura, CA Leite Filho, T Scarpelli, EBLD Domenico
    Acta Paul Enferm 38, - , 2025
    2025
  • Click Ordering Lateralization Test: Applicability and feasibility of a new paradigm for assessing sound lateralization behavior
    E Della Colette, CA Leite Filho, CM Rabelo, F Musiek, E Schochat
    International Journal of Pediatric Otorhinolaryngology 189, 112215 , 2025
    2025
  • Validação do teste de mascaramento temporal sucessor e investigação do processamento temporal de músicos com ouvido absoluto
    CA Leite Filho, E Schochat
    2024