Organic Chemistry, Analytical Chemistry, Physical and Theoretical Chemistry, Spectroscopy
14
Scopus Publications
112
Scholar Citations
6
Scholar h-index
4
Scholar i10-index
Scopus Publications
A STUDY OF DEVELOPMENT AND VALIDATION OF A METHOD FOR SIMULTANEOUS ESTIMATION OF LOBEGLITAZONE SULFATE AND GLIMEPIRIDE USING REVERSEDPHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY IN DOSAGE FORM AND CHARACTERIZATION OF DEGRADANTS USING LIQUID CHROMATOGRAPHY–MASS SPECTROMETRY RAVI CH, KIRAN KUMAR K, KRISHNAVENI G Asian Journal of Pharmaceutical and Clinical Research, 2025 Objectives: A novel, speedy, and accurate high-performance liquid chromatography approach has been established for quantitatively analyzing lobeglitazone sulfate and glimepiride. Methods: In this method, the drugs were separated using Inertsil Octadecylsilyl (ODS) 250 × 4.6 mm, 5 μm column with a flow rate of 1 mL/min. The buffer consists of 1 mL of formic acid, which is dissolved in 1 L Milli-Q water, and a mobile phase consisting of a 50:50 (v/v) mixture of 0.1% formic acid and acetonitrile. The 260 nm wavelength was used for detection. Results: Lobeglitazone sulfate concentrations ranging from 12.5 μg/mL to 75 μg/mL and glimepiride concentrations from 25 μg/mL to 150 μg/mL show good linearity in the suggested approach. The limit of detection and limit of quantification values were 0.3 μg/mL, 1.0 μg/mL and 0.15 μg/mL, 0.5 μg/mL for glimepiride and lobeglitazone sulfate, respectively. All the parameters of accuracy, specificity, and method precision were all within the acceptable limit. Conclusion: In the forced degradation studies, the degradation products were characterized by the use of liquid chromatography–mass spectrometry. The current method was found to be simple, economical, suitable, and validated according to the International Council for Harmonization guidelines.
Synergistic Influence of Ni Substitution on Synergistic Influence of Ni substitution on Structural, Magnetic and Photocatalysis Properties of Y0.85La0.15FeO3 Nanomaterials Kalakonda Sajini, Rama Sekhara Reddy Dachuru, Gudela Krishnaveni Ecs Journal of Solid State Science and Technology, 2025 Y0.85La0.15Fe1−x Ni x O3 (where 0 ≤ x ≤ 0.15) nanomaterials were fabricated via sol-gel method. The structural characterization and estimation of crystallite size of synthesized nanopowders were performed using X-ray powder diffraction (XRD) and scanning electron microscopy (SEM), respectively. However optical band gap and magnetic behavior of these nanopowders were estimated using UV–vis absorption and Vibrating-sample magnetometer (VSM). An orthorhombic structure with pure phase for the synthesized samples (for x = 0, 0.05, 0.10 and 0.15) was observed through XRD analysis. The calculated tolerance factor was increased from 0.8132 to 0.8411 with an increase of Ni2+ concentration from 0 to 15 mol % in Y0.85La0.15Fe1-x Ni x O3. Due to electronic transitions of valence band (2p level of oxygen) to conduction band (3 d level of iron), the p-d transition was observed in range of 500 to 600 nm using the UV–vis absorption spectrum. Due to decrease of crystallite size from 125 nm to 108 nm, an increased optical band gap from 1.98 eV to 2.06 eV was noticed in the synthesized samples. The enhanced saturation magnetization (Ms) value was observed for Y0.85La0.15Fe0.85Ni0.15O3 nanomaterials when compared to that of other samples in this study. The Ni ion doped at Fe site leads to the variation of oxidation state in Fe atom as a consequence increase of super exchange interaction Fe3+-O2—Fe2+, Y3+/La3+-O2−-Fe3+/Fe2+, Fe3+/Ni2+-O2− -Fe3+/Fe2+, Y3+/La3+-O2−- Ni2+ compared to that super exchange interaction of un-doped YFeO3 sample. X-ray photoelectron spectroscopy (XPS) technique was employed to determine the oxidation state of each atom in the sample. Rate constant k obtained for x = 0 and x = 0.15 were found to be 0.0083 min−1 and 0.0132 min−1 respectively. In summary, the obtained result indicates that Ni substitution at Fe site is greatly influenced on structural and physical properties of Y0.85La0.15FeO3 nanomaterials.
Synergistic Influence of Doping and Co-Doping of Trivalent Ions (La+3 and Al+3) on YFeO3 Nanomaterials Sajini Kalakonda, Rama Sekhara Reddy Dachuru, Krishnaveni Gudela Physica Status Solidi B Basic Research, 2024 Herein, the structural, optical, and magnetic properties of Y0.85La0.15FexAlyO3: (x; y) where x = 1; y = 0, x = 0.975; y = 0.025, x = 0.95; y = 0.05, and x = 0.9; y = 0.1 nanomaterials obtained from sol–gel method are reported. The X‐ray powder diffraction (XRD) for the structural characterization, scanning electron microscopy for crystallite size estimation, ultraviolet–visible absorption for optical studies, and vibrating‐sample magnetometer for magnetic studies are used in this investigation. An increase of orthorhombic crystal structure with an increase of Al content in the sample is observed from XRD studies. The existence of all the elements present in the samples is observed from energy‐dispersive X‐ray spectroscopy. The optical bandgap increases from 2.04 to 2.10 eV with an increase of Al concentration from 0 to 0.05. The observed magnetization value is 3.14 emu g−1 for y = 0.05, which is higher than y = 0 (2.11 emu g−1) and y = 0.024 (2.58 emu g−1). In summary, the obtained result (x = 0.95; y = 0.05) can be useful for different magnetic‐based applications.
Structural and Magnetic Properties of Y0.85La0.15Fe1−(4/3)xTixO3 (where (x = 0, 0.025, 0.05 and 0.075) Nanomaterials Derived from Sol-Gel Route Sajini Kalakonda, Rama Sekhara Reddy Dachuru, Krishnaveni Gudela Ecs Journal of Solid State Science and Technology, 2024 Y0.85La0.15Fe1−(4/3)xTixO3 (where (x = 0, 0.025, 0.05 and 0.075) nanomaterials were prepared using tartare acid assisted sol-gel method. Various analytical characterization techniques such as X-ray powder diffraction (XRD), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), UV–vis absorption, Vibrating-sample magnetometer (VSM) and dielectric spectroscopy were employed to characterize the synthesized nanomaterials. Downward shifted of (121) and (002) planes were observed with an increasing of Ti concentration at Fe site through XRD study. The ability of the prepared nano-powders to absorb visible light was demonstrated by the investigation of diffuse reflectance spectra, which showed a decline in bandgap from 2.13 eV to 2.06 eV. XPS studies revealed that Y and La atoms are existed in +3 oxidation state, Fe atom is existed in mixed (+2 and +3) oxidation state and Ti atom is existed in mixed (+3 and +4) oxidation state. The highest magnetization value was observed for x = 0.05 sample through VSM study. High dielectric constant, low dielectric loss and low conductivity values were also observed for Y0.85La0.15Fe1−(4/3)xTixO3 (where (x = 0.05)).
Defluoridation of Water by Biowaste Material - A Study of Adsorption Kinetics and Isotherms K. Kiran Kumar, Ratnakaram Venkata Nadh, Kaza Somasekhara Rao, G. Krishnaveni Nature Environment and Pollution Technology, 2023 Human beings experience adversative effects due to the large fluoride concentrations present in potable water. Because of the low cost and simple operation, the extensively acknowledged process is adsorption. The objective of this study is to investigate the performance of some of the prepared carbons from bio-waste materials viz., Citrus limon, Citrus nobilis, Pithecellobium dulce, and Bombax malabaricum sheaths in defluoridation. Initial concentration, particle size, agitation time, adsorbent dose, and pH were the different parameters chosen to study their effect on adsorption. Studied the adsorption kinetics. Further suitability to adsorption isotherms was reviewed.
Simultaneous estimation of aflatoxins (B1, B2, G1 and G2) by liquid chromatography coupled with mass spectrometry (LC-MS) in corn samples O. Sailaja, M. Manoranjani, G. Krishnaveni Asian Journal of Chemistry, 2021 Aflatoxins produced by Aspergillus flavins and Aspergillus pasasiticus have been investigated in the corn (maize) collected in different locations in Andhra Pradesh state, India. In the present study, 24 corn samples collected from different harvest, storage and dumping areas were analyzed for detection of aflatoxin contamination by liquid chromatography coupled with mass spectrometry (LC-MS). Mixed aflatoxin working standard solutions with a concentration of 10, 20, 30, 40, 50 and 60 ng/mL were prepared and followed by instrumental analysis and the retention times of the sample chromatograms were compared with the standard aflatoxins B1, B2, G1 and G2 retention times in order to determine the contamination. The findings revealed that among 24 collected samples, only 10 samples have been found positive for aflatoxins contamination when subjected to LC-MS analysis. Co-occurrence of aflatoxin was identified in the most of the samples. Even though 10 samples were tested positive total aflatoxin content in the most positive are found within the acceptable limits (30 μg/kg) and samples collected at dumping areas (S4, S8 and S10) show the presence of exceeding quantity than the limits described by FSSAI. Total aflatoxin content in the most positive were found within the acceptable limits (30 μg/kg) and the samples collected at dumping areas S4 (40.9 μg/kg), S8 (53.2 μg/kg) and S10 (71.86 μg/kg) had shown exceeding limits. The sample S7 collected from the storage was also found positive of presence of aflatoxin G2- 13.49 μg/kg and B2-21.14 μg/kg with total aflatoxin of 34.65 μg/kg. High contamination of these dumping areas may lead to contamination of storage points nearer to these areas. Present results showed that the corn samples at dumping areas were found to be contaminated with the Aspergillus flavins and Aspergillus pasasiticus.
Air pollution tolerance index of selected plants in Vijayawada city, Andhra Pradesh International Journal of Green Pharmacy, 2017
Phytochemical screening and quantitative analysis of hexane, acetone, methanol & water extracts of Salicornia virginica by UV-spectrophotometry Der Pharmacia Lettre, 2016
Seasonal variations in physico-chemical characteristics of ground water collected from Kondapalli Santhi Nagar near Vijayawada thermal power plant (VTPS) Rasayan Journal of Chemistry, 2016
Physico chemical properties and heavy metal content of water collected from Ibrahimpatnam nearby VTPS-Vijayawada International Journal of Pharma and Bio Sciences, 2015
Simultaneous determination of famotidine and ibuprofen in combined pharmaceutical dosage form by RP-HPLC method International Journal of Pharma and Bio Sciences, 2013
Synthesis and characterization of novel biodegradable aliphatic copolyesters - poly(ethylene sebacate-co-propylene succinate) and poly(ethylene sebacate-co-propylene adipate) Journal of Chemical and Pharmaceutical Research, 2012
A novel RP-HPLC method for the quantification of celecoxib in formulations Research Journal of Pharmaceutical Biological and Chemical Sciences, 2012
RECENT SCHOLAR PUBLICATIONS
Synergistic Influence of Ni substitution on Structural, Magnetic and Photocatalysis Properties of Y 0.85 La 0.15 FeO 3 Nanomaterials K Sajini, RSR Dachuru, G Krishnaveni ECS Journal of Solid State Science and Technology 14 (4), 043006 , 2025 2025
Pressure Pump Reagent Bottle KRM Dr.Gudela Krishnaveni, Dr.D.Rama Sekhara Reddy, Kalakonda Sajini, Dr ... IN Patent 431415-001 , 2024 2024
Structural and Magnetic Properties of Y 0.85 La 0.15 Fe 1−(4/3)x Ti x O 3 (where (x = 0, 0.025, 0.05 and 0.075) Nanomaterials Derived from Sol-Gel Route S Kalakonda, RSR Dachuru, K Gudela ECS Journal of Solid State Science and Technology 13 (8), 083002 , 2024 2024 Citations: 1
Exploring the Structural Attributes of Molecules in Pharmaceuticals G Krishnaveni, O Sailaja PROCEEDINGS OF ICCBAD’24, 318 , 2024 2024
Synergistic Influence of Doping and Co‐Doping of Trivalent Ions (La+ 3 and Al+ 3) on YFeO3 Nanomaterials S Kalakonda, RSR Dachuru, K Gudela physica status solidi (b), 2400190 , 2024 2024 Citations: 2
Defluoridation of Water by Biowaste Material–A Study of Adsorption Kinetics and Isotherms. KK Kumar, RV Nadh, KS Rao, G Krishnaveni Nature Environment & Pollution Technology 22 (4) , 2023 2023 Citations: 1
A Modern Method for Analyzing Related Substances of Cabotegravir and Rilpivirine Using RP-HPLC, along with the Characterization of their Degradation Products Via LCMS K Gudela Asian Journal of Pharmaceutics (AJP) 17 (2) , 2023 2023
Determination of Sodium, Potassium, and Calcium Content in Diverse Mango Fruit Varieties and Mango Flavoured Beverages from Nuzvid, EluruDistrict, AP through Flame Photometry O V.Nagalakshmi1 , Krishanveni, G2 , Kiran Kumar Katare3 , Sailaja European Chemical Bulletin 12 (5), 5855 – 5866 , 2023 2023
Phytochemical Analysis and Flame Photometric Studies of Hexane and Chloroform leaf extracts of Inula Recemosa BKT Krishnaveni G, Sailaja O, Kiran Kumar Katare European Chemical Bulletin 12 (2), 311-320 , 2023 2023
ONE POT REACTION FOR THE SYNTHESIS OF AMIDES FROM TOLUENE USING TERTIARY BUTYL AMMONIUM IODIDE KGSO Bhagya KumarTatavarti BioGecko 11 (4), 17-22 , 2022 2022
Evaluation of Fumonisins Contamination using Liquid Chromatography Mass Spectrometry in Corn Samples Collected from Different Locations S Ommi Asian Journal of Pharmaceutics (AJP) 16 (2) , 2022 2022
Simultaneous Estimation of Aflatoxins (B1, B2, G1 and G2) by Liquid Chromatography Coupled with Mass Spectrometry (LC-MS) in Corn Samples GK O. Sailaja, M. Manoranjani Asian Journal of Chemistry 33 (3), 521-526 , 2021 2021 Citations: 3
A Review on Contamination, Effects and Analysis of Aflatoxins in Different Food Products S Ommi, M Medikonda, K Gudela 2019
Asian Journal of Organic & Medicinal Chemistry KR Devi, KK Kumar, G Krishnaveni 2019
A Review on Contamination, Effects and Analysis of Aflatoxins in Different Food Products MMKG Sailaja Ommi International Journal of Pharmacy and Biological Sciences 9 (2), 371-378 , 2019 2019
New Extractive Spectrophotometric Method Development and Validation for the Estimation of Danazol in Pharmaceutical Formulations KKKGK K. Rama Devi Asian journal of organic & medicinal chemistry 4 (1), 36-39 , 2019 2019
IDENTIFICATION AND HPLC QUANTIFICATION OF AFLATOXINS IN GROUNDNUT (ARACHIS HYPOGAEA L.) SAMPLES COLLECTED IN RAYALASEEMA AREA, ANDHRA PRADESH MMKG Sailaja Ommi international journal of pharmaceutical sciences and Research 10 (3), 1312-1318 , 2019 2019 Citations: 4
Identification and High-performance Liquid Chromatography Quantification of Aflatoxins in Red Chili (Capsicum annuum L.) in Guntur, Andhra Pradesh, India MM Ommi Sailaja, G. Krishnaveni Asian Journal of Pharmaceutics 11 (4), S933-S937 , 2017 2017 Citations: 8
Stability Indicating Development and Validation of Ultraviolet Spectrophotometric Methods for the Simultaneous Estimation of Bromhexine and Cephalexin in their Combined … GK K. Kiran Kumar Asian Journal of Pharmaceutics 11 (4), S938-S943 , 2017 2017 Citations: 3
Air pollution tolerance index of selected plants in Vijayawada city, Andhra Pradesh G Krishnaveni International Journal of Green Pharmacy (IJGP) 11 (04) , 2017 2017 Citations: 24
MOST CITED SCHOLAR PUBLICATIONS
Air pollution tolerance index of selected plants in Vijayawada city, Andhra Pradesh G Krishnaveni International Journal of Green Pharmacy (IJGP) 11 (04) , 2017 2017 Citations: 24
Simultaneous determination of famotidine and ibuprofen in combined pharmaceutical dosage form by RP-HPLC method G Krishnaveni, P Sathyannarayana Int J Pharm Bio Sci 4 (3), 655-662 , 2013 2013 Citations: 18
Phytochemical screening and quantitative analysis of hexane, acetone, methanol and water extracts of Salicornia virginica by UV-spectrophotometry G Krishnaveni, O Sailaja, KK Kumar Der Pharmacia Lettre 8 (16), 52-56 , 2016 2016 Citations: 14
Method development and validation for simultaneous determination of ezetimibe and simvastatin in combined pharmaceutical dosage form by Rp-Hplc method G Krishnaveni, PVV Sathyannarayana International Journal of Pharmaceutical and Life Sciences 2 (2), 60-69 , 2013 2013 Citations: 14
Identification and High-performance Liquid Chromatography Quantification of Aflatoxins in Red Chili (Capsicum annuum L.) in Guntur, Andhra Pradesh, India MM Ommi Sailaja, G. Krishnaveni Asian Journal of Pharmaceutics 11 (4), S933-S937 , 2017 2017 Citations: 8
Identification And Estimation Of Phytochemicals From The Plant Pedicularis Bicornuta Leaf Extract By Uv-Spectrophotometry KM G Krishnaveni, O Sailaja www.researchdesk.net 3 (1), 410-418 , 2014 2014 Citations: 6
A Novel RP-HPLC method for the Quantification of Celecoxib in Formulations SPVV Krishnaveni.G Research Journal of Pharmaceutical, Biological and Chemical Sciences 3 (1 … , 2012 2012 Citations: 6
IDENTIFICATION AND HPLC QUANTIFICATION OF AFLATOXINS IN GROUNDNUT (ARACHIS HYPOGAEA L.) SAMPLES COLLECTED IN RAYALASEEMA AREA, ANDHRA PRADESH MMKG Sailaja Ommi international journal of pharmaceutical sciences and Research 10 (3), 1312-1318 , 2019 2019 Citations: 4
First Derivative UV-Spectrophotometric Method for The Simultaneous Estimation of Neomycin and Betamethasone in Their Combined Dosage Form KK Kumar, O Sailaja, G Krishnaveni International Journal of Research and Reviews in Pharmacy and Applied … , 2016 2016 Citations: 4
Simultaneous Estimation of Aflatoxins (B1, B2, G1 and G2) by Liquid Chromatography Coupled with Mass Spectrometry (LC-MS) in Corn Samples GK O. Sailaja, M. Manoranjani Asian Journal of Chemistry 33 (3), 521-526 , 2021 2021 Citations: 3
Stability Indicating Development and Validation of Ultraviolet Spectrophotometric Methods for the Simultaneous Estimation of Bromhexine and Cephalexin in their Combined … GK K. Kiran Kumar Asian Journal of Pharmaceutics 11 (4), S938-S943 , 2017 2017 Citations: 3
Simple, Sensitive, Specific and Validated Calorimetric Method Development for the Quantitative Estimation of Melphalan Hydrochloride in Bulk and Pharmaceutical Dosage forms KLR G.Krishnaveni, O.Sailaja SPJPBS 2 (1), 110-117 , 2014 2014 Citations: 3
Synergistic Influence of Doping and Co‐Doping of Trivalent Ions (La+ 3 and Al+ 3) on YFeO3 Nanomaterials S Kalakonda, RSR Dachuru, K Gudela physica status solidi (b), 2400190 , 2024 2024 Citations: 2
Structural and Magnetic Properties of Y 0.85 La 0.15 Fe 1−(4/3)x Ti x O 3 (where (x = 0, 0.025, 0.05 and 0.075) Nanomaterials Derived from Sol-Gel Route S Kalakonda, RSR Dachuru, K Gudela ECS Journal of Solid State Science and Technology 13 (8), 083002 , 2024 2024 Citations: 1
Defluoridation of Water by Biowaste Material–A Study of Adsorption Kinetics and Isotherms. KK Kumar, RV Nadh, KS Rao, G Krishnaveni Nature Environment & Pollution Technology 22 (4) , 2023 2023 Citations: 1
PHYSICO CHEMICAL PROPERTIES AND HEAVY METAL CONTENT OF WATER COLLECTED FROM IBRAHIMPATNAM NEARBY VTPS-VIJAYAWADA TBANDOS G. KRISHNAVENI International Journal of Pharma and Bio Sciences 6 (3), 42-49 , 2015 2015 Citations: 1
Synergistic Influence of Ni substitution on Structural, Magnetic and Photocatalysis Properties of Y 0.85 La 0.15 FeO 3 Nanomaterials K Sajini, RSR Dachuru, G Krishnaveni ECS Journal of Solid State Science and Technology 14 (4), 043006 , 2025 2025
Pressure Pump Reagent Bottle KRM Dr.Gudela Krishnaveni, Dr.D.Rama Sekhara Reddy, Kalakonda Sajini, Dr ... IN Patent 431415-001 , 2024 2024
Exploring the Structural Attributes of Molecules in Pharmaceuticals G Krishnaveni, O Sailaja PROCEEDINGS OF ICCBAD’24, 318 , 2024 2024
A Modern Method for Analyzing Related Substances of Cabotegravir and Rilpivirine Using RP-HPLC, along with the Characterization of their Degradation Products Via LCMS K Gudela Asian Journal of Pharmaceutics (AJP) 17 (2) , 2023 2023