David Pakizer

@lf.osu.eu

Atherosclerosis Research Working Group, Centre for Health Research, Department of Medical Imaging
Faculty of Medicine, University of Ostrava

David Pakizer

RESEARCH, TEACHING, or OTHER INTERESTS

Radiology, Nuclear Medicine and imaging, Neurology (clinical)
20

Scopus Publications

122

Scholar Citations

6

Scholar h-index

3

Scholar i10-index

Scopus Publications

  • Expanding the stroke risk paradigm: Left atrial size as a trigger for preventive action
    David Pakizer, David Školoudík
    European Journal of Internal Medicine, 2026
  • Contrast-Associated Acute Kidney Injury After Thrombectomy for Ischemic Stroke
    Ghil Schwarz, Angelo Cascio Rizzo, Gareth Ambler, Pawel Wrona, Agnieszka Slowik, Szymonn Kotas, Mohamed F. Doheim, Alhamza R. Al-Bayati, Raul G. Nogueira, Ana Paiva Nunes, Patricia Ferreira, Matteo Paolucci, Andrea Zini, Luigi Simonetti, Norbert Leško, Jakub Fedorko, Zuzana Gdovinova, Luca Scarcia, Erwah Kalsoum, Firas Farhat, Morin Beyeler, Adnan Mujanovic, Marcel Arnold, Torcato Meira, Marta Morais, Leonor Francisco, Marcin Wiacek, Paulina Pudło, Halina Bartosik-Psujek, Patricia Calleja, Fernando Ostos, David Seoane, Anca Negrila, Razvan Alexandru Radu, Cristina Tiu, Sami Al Kasab, Ahmad Abu Qdais, Imad Samman Tahhan, Oscar Ayo-Martin, Maria Paya, Juan David Molina-Nuevo, Beata Labuz-Roszak, Danilo Toni, Karolina Moszko, Mateusz Łukasz Roszak, Manuela De Michele, Elena Barrile, Prasanna Eswaradass, Margaret Houghton, Tiffany Barkley, Amir Ali, Jelle Demeestere, Wayne Martin Bauknight, Sunil Sheth, Louise Maes, Anke Wouters, João Pedro Marto, Josè Blazer Costa, Nicola D. Loizzo, Andrea Romi, Carmelo Tiberio Currò, Piotr Luchowski, Maksymilian Seweryn, Konrad Rejdak, Piers Klein, Mohamad Abdalkader, Valentina Saia, Antioco Sanna, Tiziana Tassinari, Maurizio Acampa, Francesca Rosini, Rossana Tassi, Marta Bilik, Anna Maria Bandzarewicz-Samcik, Jiangyong Min, Naser HajAissa, Marilena Mangiardi, Sabrina Anticoli, Enrico Pampana, Carlos Hervás-Testal, Ricardo Rigual, Blanca Fuentes, Davide Strambo, Carl Manuata Tetaria, Guillaume Saliou, Andrea Salvatore Caramma, Davide Maimone, Pier Andrea Rizzo, Marco Moci, Irene Scala, Antonio Cruz-Culebras, Rocío Vera Lechuga, Sebastián García-Madrona, Giovanni Merlino, Mariarosaria Valente, Arianna Cella, Manuel Bolognese, Lehel-Barna Lakatos, Grzegorz M. Karwacki, Paolo Candelaresi, Vincenzo Andreone, Carlo Maurea, Roberto Tarletti, Angelica Mele, Antonio Ciacciarelli, Michele Alessiani, Gabriella Monteforte, David Pakizer, Martin Roubec, David Školoudík, Fenne Vandervorst, Sylvie De Raedt, Martijn Verdam, Josef Bartoš, Martin Sramek, Valentina Mazzoleni, Luca Quilici, Dario Alimonti, Jessica Moller, Ilaria Maestrini, Marina Diomedi, Giordano Lacidogna, Osama O. Zaidat, Eugene Lin, Mohammad Almajali, Claudio Baracchini, Matteo Zaccagnino, Federica Viaro, Alessandro Pezzini, Giulia Avola, Chiara Ferraro, Milena Świtońska, Paulina Sobieszak-Skura, Grzegorz Meder, Lukas Mayer-Suess, Michael Knoflach, Elke R. Gizewski, Matthew R. Common, Patrick Nicholson, Sarah Power, Marta Nowakowska-Kotas, Michal Puła, Maciej Guzinski, Soledad Pérez-Sánchez, Joan Montaner, Alexandra Sevilla Bravo, Simona Marcheselli, Francesca Vodret, Costanza Maria Rapillo, Liliana Pereira, Miguel Rodrigues, Adam Jaros, Martin Kovar, Jan Vojik, Gloria Valcamonica, Serena Gallo Cassarino, Alessandra Cardillo, Marco Petruzzellis, Silvia Grimaldi, Nicola Marrone, Ameer E. Hassan, Samantha Miller, Mohammad W. Khasawneh, Valentina Poretto, Simone Tonello, Saverio Tollot, Aleksander DęBiec, Jacek Staszewski, Adam Stepien, Francisco Bernardo, Jorge Ferrao, Marialuisa Zedde, Rosario Pascarella, Alessandra Sanna, Rossella Meloni, Sennur Delibas, Simona Sacco, Maria Grazia Vittorini, Raffaele Ornello, Marina Mannino, Valeria Terruso, Marco Filizzolo, Emily Hall, Christine Roffe, Malgorzata Dorobek, Justyna Zielińska-Turek, Giuseppe Scopelliti, Leonardo Pantoni, Guglielmo C. Pero, Antonio Macera, Amedeo Cervo, Simone Bellavia, Mine Sezgin, Yavuz Dilmen, Esme Ekizoglu, Georgios Tsivgoulis, Aikaterini Theodorou, Vlad Tiu, Cristina Aura Panea, Simona Petrescu, Mariangela Piano, Thanh N. Nguyen, Maria Sessa, and
    Neurology, 2026
    BACKGROUND AND OBJECTIVES: Contrast-associated acute kidney injury (CA-AKI) is a potentially preventable complication after exposure to iodinated contrast media. In patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke (AIS), the incidence and clinical impact are poorly characterized, and no validated prediction tool is currently available. The aim of this study was to assess the incidence and prognostic significance of CA-AKI in EVT-treated patients with AIS and to develop and validate a predictive score. METHODS: < 0.05), and coefficient-based scoring after categorization of continuous predictors, with internal validation by bootstrap to obtain optimism-adjusted estimates. RESULTS: Among 6,638 patients (median age 74 years; 48.7% male), CA-AKI occurred in 326 (4.9%) and was independently associated with in-hospital mortality (adjusted odds ratio [aOR] 2.269; 95% CI 1.615-3.190), higher 90-day mRS scores (adjusted common odds ratio 1.584; 95% CI 1.110-2.258), and 90-day severe disability or death (aOR 1.530; 95% CI 1.057-2.216). A preprocedural risk model including 12 routine clinical variables-sex, ethnicity, arterial hypertension, dyslipidemia, chronic kidney disease, antiplatelet therapy, NIH Stroke Scale score at admission, serum glucose, estimated glomerular filtration rate, hemoglobin, mean arterial pressure, and IV thrombolysis-demonstrated acceptable discrimination (area under the receiver operating characteristic curve 0.710 [95% CI 0.682-0.738]; precision-recall area under the curve 0.13 [95% CI 0.10-0.16]), good calibration (slope 0.870 [95% CI 0.759-0.928]), good overall performance (Brier score 0.045 [95% CI 0.042-0.049]). A second model that included EVT-related variables (e.g., contrast volume) showed similar performances. DISCUSSION: In this large, international cohort, CA-AKI occurred in approximately 1 in 20 EVT-treated patients with AIS and was independently associated with poor outcomes. A simple preprocedural risk score enables early identification of high-risk individuals and may support preventive strategies.
  • Carotid Endarterectomy Randomized Trials: Overview
    David Pakizer, David Školoudík
    Surgical and Interventional Treatment of Cerebral Ischemia Basic Science to Clinical Practice, 2026
  • Emergent Carotid Stenting During Endovascular Therapy for Isolated Cervical Internal Carotid Artery Occlusion
    Christoph Riegler, João Pedro Marto, Pimrapat Gebert, Tilman Reiff, Marek Sykora, Marcin Wiącek, David Pakizer, André Araújo, Adrien ter Schiphorst, João André Sousa, Arno Reich, Belen Flores Pina, Lukas Mayer-Suess, Cristina Hobeanu, Marialuisa Zedde, João Nuno Ramos, Georgios Tsivgoulis, Pedro Castro, Sven Poli, José Nuno Alves, Anne Dusart, Blanca Fuentes, Herbert Tejada Meza, Jelle Demeestere, Susanne Wegener, Lars Kellert, Patricia Calleja, Cristina Panea, Christoph Vollmuth, Liliana Pereira, Ronen R. Leker, Timo Uphaus, Andrea Zini, Henrik Gensicke, Gauthier Duloquin, Taraneh Ebrahimi, Alexander Salerno, Cristina Tiu, Thanh N. Nguyen, Sebastian García-Madrona, Marta Bilik, Shadi Yaghi, Halina Sienkiewicz-Jarosz, Michał Karliński, Stefan Krebs, Eva Hurtíková, Nathalia Ferreira, João Sargento-Freitas, João Pinho, Isabel Rodriguez Caamaño, Elke Ruth Gizewski, Pierre Seners, Rosario Pascarella, Klearchos Psychogios, Alexandra Gomez Exposito, Sara Gomes, Flavio Bellante, Jorge Rodríguez-Pardo, Mario Bautista Lacambra, Robin Lemmens, Corinne Inauen, Johannes Wischmann, Fernando Ostos, Vlad Tiu, Karl Georg Haeusler, Miguel Rodrigues, Issa Metanis, Marianne Hahn, Maria Maddalena Viola, Simon Truessel, Yannick Bejot, Louisa Nitsch, Davide Strambo, Elena Oana Terecoasa, Mohamad Abdalkader, Alicia De Felipe, Farhan Khan, Caroline Arquizan, Manuel Ribeiro, Martin Roubec, Izabella Tomaszewska-Lampart, Julia Ferrari, Peter Ringleb, Christian H. Nolte
    Journal of Stroke, 2026
    Background and Purpose In patients with ischemic stroke and isolated cervical internal carotid artery occlusion (c-ICA-O), endovascular therapy (EVT) can improve cerebral perfusion. To maintain vessel patency, EVT is frequently combined with carotid artery stenting (CAS). We assessed the efficacy and safety of emergent CAS during EVT for isolated c-ICA-O.Methods This retrospective multinational cohort study (42 centers) included consecutive patients who underwent EVT for isolated c-ICA-O within 24 hours from the time last seen well. Patients who underwent emergent CAS were compared with those who did not. Co-primary outcomes were c-ICA vessel patency and symptomatic intracerebral hemorrhage (sICH) 24 hours post-EVT. Secondary outcomes included any intracerebral hemorrhage (ICH) at 24 hours and disability at 3 months (modified Rankin Scale [mRS] shift). Outcomes were adjusted using inverse probability of treatment weighting.Results Of 317 patients (mean age, 68.6 years [standard deviation, 12.9]; median National Institutes of Health Stroke Scale 11 [interquartile range, 6–17]; 26.8% female), 219 (69.1%) underwent CAS, whereas 98 (30.9%) did not. At 24 hours, vessel patency was more common after CAS (83.5% vs. 40.7%; adjusted odds ratio [aOR], 9.45; 95% confidence interval [CI], 4.91–18.17); sICH rates did not differ (2.3% vs. 3.1%; aOR, 0.92; 95% CI, 0.18–4.73). Any ICH was more common after CAS (19.3% vs. 9.3%; aOR, 2.50; 95% CI, 1.12–5.60). CAS was not associated with mRS at 3 months (adjusted common odds ratio, 0.98; 95% CI, 0.62–1.56).Conclusions In patients undergoing EVT for isolated c-ICA-O, emergent CAS was technically effective and reasonably safe. More frequent vessel patency in patients who underwent CAS did not translate into improved functional outcome at 3 months.
  • A comparative study between CT angiography and flow parameters in hemodynamic phantom of carotid stenosis evaluated by duplex sonography
    Anna Seidlová, Norbert Svoboda, Richard Voldřich, Petra Kešnerová, Roman Matějka, David Pakizer, David Školoudík, David Netuka
    3D Printing in Medicine, 2025
    BACKGROUND: The use of 3D-printed hemodynamic phantom of a stenotic carotid artery has not been extensively investigated. Our study aims to address this gap by exploring the correlation between CTA and flow parameters in hemodynamic phantom. METHODS: Patients with carotid stenosis were included in a prospective study. A realistic phantoms of carotid artery stenoses were 3D-printed based on CT angiography. Stenosis severity and hemodynamic flow parameters in the phantom evaluated using duplex sonography were correlated with CTA. The primary outcome was to compare the evaluation of the percentage of stenosis based on the measurement of diameter reduction and area reduction of the carotid artery among CTA, a 3D model constructed from CTA data, and ultrasound measurement of stenosis percentage within the 3D printed phantom. The secondary outcome was to determine whether the percentage of stenosis measured by ultrasound in B-mode or ultrasound-measured flow velocities (PSV, EDV) better correlates with the stenosis percentage derived from CTA and the phantom. RESULTS: The study included 95 subjects (average age 71 years, 75% male) with carotid stenosis, 39% were symptomatic. Significant correlations were found between ultrasound B-Mode findings on the phantom and CTA, with the strongest correlations for area reduction (Spearman r = 0.615, p < 0.0001) and diameter reduction (Spearman r = 0.465, p < 0.0001). The most robust correlation between PSV and EDV in stenosis and the percentage of stenosis was identified between PSV in stenosis and the percentage of stenosis by diameter reduction, as evaluated through ultrasound. The Spearman correlation coefficient revealed a relatively strong correlation, with a value of r = 0.444 (p < 0.0001), and the Kendall Tau correlation coefficient also demonstrated significance, with a value of r = 0.302 (p < 0.0001). CONCLUSIONS: A significant correlation between CTA and duplex sonography measurements on the carotid phantom was demostrated, suggesting the potential utilization of the phantom in testing hemodynamic parameters of carotid stenosis.
  • Histologically Verified Carotid Plaque Characteristics by Ultrasound: A Diagnostic Accuracy Systematic Review
    David Pakizer, Jiří Kozel, Jolanda Elmers, Janusz Feber, Patrik Michel, David Školoudík, Gaia Sirimarco
    Ultrasound in Medicine and Biology, 2025
    Ultrasound (US) has been considered the first-line diagnostic technique for evaluating carotid atherosclerosis, where plaque composition plays a key role in stroke risk. We aimed to analyze the diagnostic accuracy of carotid plaque characteristics using US techniques compared to histology in patients with symptomatic/asymptomatic carotid plaques. After prospective study registration in PROSPERO, we searched Medline Ovid, Embase.com, Cochrane Library, and Web of Science without any search limitation for the diagnostic accuracy of US in detecting carotid plaque features based on histology. From 8168 studies, 63 were included evaluating 13 histologically verified plaque characteristics by 14 different US techniques. Diagnostic accuracies for all plaque characteristics usually varied between 35% and 100% without a trend towards increasing accuracy over the last 40 y but were affected by large heterogeneity. In characteristics with >5 diagnostic accuracy comparisons, the highest diagnostic performance was found for detection of calcification (mean sensitivity 65.7%/mean specificity 84.7%), fibrous tissue (61.2%/84.9%), vulnerable/unstable plaque (76.3%/70.3%), and stable plaque (63.2%/82.7%). However, several advanced techniques investigated showed high diagnostic accuracy, promising interesting diagnostic options for the future. Carotid US allows for widely available and reliable evaluation of atherosclerotic plaque morphology by conventional and advanced techniques. Registration: PROSPERO ID CRD42022329690 (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=329690).
  • Non-invasive imaging of individual histological carotid plaque characteristics: A diagnostic accuracy meta-analysis
    David Pakizer, Patrick Taffé, Jiří Kozel, Jolanda Elmers, Janusz Feber, Vincent Dunet, Patrik Michel, David Školoudík, Gaia Sirimarco
    Atherosclerosis, 2025
  • Endovascular treatment for isolated cervical internal carotid artery occlusion: ETIICA study
    João Pedro Marto, Christoph Riegler, Pimrapat Gebert, Tilman Reiff, Marek Sykora, Marcin Wiącek, David Pakizer, André Araújo, Adrien ter Schiphorst, João André Sousa, Arno Reich, Belen Flores Pina, Lukas Mayer-Suess, Cristina Hobeanu, Marialuisa Zedde, João Nuno Ramos, Georgios Tsivgoulis, Pedro Castro, Sven Poli, José Nuno Alves, Anne Dusart, Blanca Fuentes, Herbert Tejada Meza, Jelle Demeestere, Susanne Wegener, Lars Kellert, Patricia Calleja, Cristina Panea, Christoph Vollmuth, Liliana Pereira, Ronen R Leker, Timo Uphaus, Andrea Zini, Henrik Gensicke, Gauthier Duloquin, Taraneh Ebrahimi, Alexander Salerno, Cristina Tiu, Thanh N. Nguyen, Sebastian García-Madrona, Marta Bilik, Shadi Yaghi, Halina Sienkiewicz-Jarosz, Michał Karliński, Stefan Krebs, Eva Hurtíková, Nathalia Ferreira, João Sargento-Freitas, João Pinho, Isabel Rodriguez Caamaño, Elke Ruth Gizewski, Pierre Seners, Rosario Pascarella, Klearchos Psychogios, Alexandra Gomez Exposito, Sara Gomes, Flavio Bellante, Jorge Rodríguez-Pardo, Mario Bautista Lacambra, Robin Lemmens, Corinne Inauen, Johannes Wischmann, Fernando Ostos, Vlad Tiu, Karl Georg Haeusler, Miguel Rodrigues, Issa Metanis, Marianne Hahn, Maria Maddalena Viola, Simon Truessel, Yannick Bejot, Louisa Nitsch, Davide Strambo, Elena Oana Terecoasa, Mohamad Abdalkader, Alicia de Felipe, Farhan Khan, Caroline Arquizan, Manuel Ribeiro, Martin Roubec, Izabella Tomaszewska-Lampart, Julia Ferrari, Peter Ringleb, Christian H. Nolte
    European Stroke Journal, 2025
    Introduction: Evidence regarding the benefit of endovascular therapy (EVT) in patients with acute ischemic stroke (AIS) due to isolated cervical internal carotid artery occlusion (c-ICA-O) is lacking. We assessed the outcomes and safety of EVT in patients with isolated c-ICA-O. Methods: Retrospective multicenter cohort study of patients with an AIS due to isolated c-ICA-O, within 24-h since last-seen-well. Comparisons were made between EVT and best medical therapy (BMT). The primary outcome was 3-months modified Rankin Scale (mRS) ordinal shift. Secondary outcomes included 3-month favorable outcome (mRS 0–2, or return to pre-stroke mRS), symptomatic intracranial hemorrhage (sICH) and any parenchymal hemorrhage. Outcomes were compared combining inverse probability of treatment weighting with regression models and propensity score matching (PSM) as sensitivity analysis. Results: We analyzed 998 patients (66.2% male, mean age 71.1 ± 13.2 years). 487 (48.8%) patients received EVT and 511 (51.2%) received BMT. Patients receiving EVT had a higher admission NIHSS [13 (7–18) vs 5 (2–13)] compared to BMT. There was no difference between EVT and BMT groups in 3-month mRS shift (adjusted common odds ratio [OR], 1.01 [95% CI 0.76–1.34]) and favorable outcome (adjusted OR [aOR] 1.16 [95% CI 0.84–1.60]). No patient (0%) in the BMT group had sICH versus 1.6% in the EVT group. Parenchymal hemorrhage was numerically higher in EVT patients (2.7% vs 0.6%; aOR 3.85 [95% CI 0.98–15.23]). PSM analysis revealed similar results. Discussion and conclusion: In patients with isolated c-ICA-O, EVT was associated with similar odds of disability and intracranial bleeding compared to BMT. Randomized-controlled clinical trials in patients with isolated c-ICA-O are warranted.
  • Carotid plaque characteristics by computed Tomography: A diagnostic accuracy systematic review
    David Pakizer, Jiří Kozel, Jolanda Elmers, Janusz Feber, Vincent Dunet, Patrik Michel, David Školoudík, Gaia Sirimarco
    Ijc Heart and Vasculature, 2025
    Beyond the stenosis degree, the carotid plaque morphology assessed by computed tomography may improve the stroke risk stratification and is recommended to be considered before interventional treatment according to current guidelines. This study aimed to systematically review the accuracy of computed tomography (CT) to detect carotid plaque characteristics compared to histology in patients with symptomatic and asymptomatic carotid plaques. We registered the protocol in PROSPERO and searched Medline Ovid, Embase.com , Cochrane Library, and Web of Science for diagnostic accuracy of CT in specific carotid plaque characteristic imaging compared to histology, without any search limitation up to May 27, 2022. Out of 8,168 studies, 20 studies that evaluated seven specific plaque characteristics were included in our systematic review. The best diagnostic performance was found for the detection of ulceration (sensitivity range 39.4–100% [mean 79.6%], specificity range 74–100% [mean 93.6%]), followed by calcification (72.7–100% [88.1%], 35.7–100% [80.1%]), lipid-rich necrotic core (63.2–95.6% [81.1%], 60–100% [80.1%]), and intraplaque hemorrhage (61.5–100% [86%], 20–99.5% [67.8%]). Only a few studies evaluated specifically vulnerable, mixed, and fibrous plaque. Diagnostic studies with larger sample sizes are needed, using novel available CT techniques that enable increasing diagnostic performance and decreasing radiation and amount of contrast agent. CT allows for highly accurate detection of carotid plaque features, particularly ulceration and calcification. These results underline the role of routine CT examinations to assess not only stenosis degree but also plaque morphology and individual patient stroke risk to better guide management. Registration: PROSPERO ID CRD42022329690 ( https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=329690 ).
  • Diagnostics Accuracy of Magnetic Resonance Imaging in Detection of Atherosclerotic Plaque Characteristics in Carotid Arteries Compared to Histology: A Systematic Review
    David Pakizer, Jiří Kozel, Jolanda Elmers, Janusz Feber, Patrik Michel, David Školoudík, Gaia Sirimarco
    Journal of Magnetic Resonance Imaging, 2025
    Carotid plaque composition represents one of the main risk factors of future ischemic stroke. MRI provides excellent soft tissue contrast that can distinguish plaque characteristics. Our objective was to analyze the diagnostic accuracy of MRI imaging in the detection of carotid plaque characteristics compared to histology in patients with symptomatic and asymptomatic carotid atherosclerosis through a systematic review. After prospective registration in PROSPERO (ID CRD42022329690), Medline Ovid, Embase.com, Cochrane Library, and Web of Science Core were searched without any search limitation up to May 27, 2022 to identify eligible articles. Of the 8168 studies, 53 (37 × 1.5 T MRI, 17 × 3 T MRI) evaluated MRI accuracy in the detection of 13 specific carotid plaque characteristics in 169 comparisons. MRI demonstrated high diagnostic accuracy for detection of calcification (3 T MRI: mean sensitivity 92%/mean specificity 90%; 1.5 T MRI: mean sensitivity 81%/mean specificity 91%), fibrous cap (1.5 T: 89%/87%), unstable plaque (1.5 T: 89%/87%), intraplaque hemorrhage (1.5 T: 86%/88%), and lipid‐rich necrotic core (1.5 T: 89%/79%). MRI also proved to have a high level of tissue discrimination for the carotid plaque characteristics investigated, allowing potentially for a better risk assessment and follow‐up of patients who may benefit from more aggressive treatments. These results emphasize the role of MRI as the first‐line imaging modality for comprehensive assessment of carotid plaque morphology, particularly for unstable plaque.Evidence Level2Technical EfficacyStage 2
  • Extracranial carotid plaque calcification and its association with risk factors for cerebrovascular events: insights from the ANTIQUE study
    David Pakizer, Dana Šalounová, David Školoudík
    Frontiers in Neurology, 2025
  • Atherosclerotic Plaque Stability Prediction from Longitudinal Ultrasound Images
    Jan Kybic, David Pakizer, Jiří Kozel, Patricie Michalčová, František Charvát, David Školoudík
    Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics, 2025
  • MRI- and CT-derived carotid plaque characteristics and stroke: Insights from the ANTIQUE study
    David Pakizer, David Netuka, Tomáš Hrbáč, Jiří Vrána, František Charvát, Tomáš Jonszta, Petra Kešnerová, Roman Herzig, Tomáš Heryán, Kateřina Langová, David Školoudík
    Kardiologia Polska, 2025
  • Diagnostic accuracy of carotid plaque instability by noninvasive imaging: a systematic review and meta-analysis
    David Pakizer, Jiří Kozel, Patrick Taffé, Jolanda Elmers, Janusz Feber, Patrik Michel, David Školoudík, Gaia Sirimarco
    European Heart Journal Cardiovascular Imaging, 2024
  • Carotid atherosclerotic plaque stability prediction from transversal ultrasound images using deep learning
    Jan Kybic, David Pakizer, Jiří Kozel, Patricie Michalčová, František Charvát, David Školoudík
    Ceska A Slovenska Neurologie A Neurochirurgie, 2024
  • Changes in Cognitive Functions after Carotid Endarterectomy and Carotid Stenting: A Decade-Apart Comparison
    Daniel Václavík, David Pakizer, Tomáš Hrbáč, Martin Roubec, Václav Procházka, Tomáš Jonszta, Roman Herzig, David Školoudík
    Biomedicines, 2024
  • Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): A randomised study
    Tomáš Hrbáč, Jiří Fiedler, Václav Procházka, Tomáš Jonszta, Martin Roubec, David Pakizer, Daniel Václavík, David Netuka, Tomáš Heryán, David Školoudík
    Stroke and Vascular Neurology, 2023
  • Risk of MRI-detected cerebral infarction and vascular events after carotid endarterectomy and carotid stenting one decade apart
    Tomáš Hrbáč, Martin Roubec, Václav Procházka, Tomáš Jonszta, David Pakizer, Tomáš Heryán, Roman Herzig, David Školoudík
    British Journal of Surgery, 2023
  • Peak systolic velocity ratio for evaluation of internal carotid artery stenosis correlated with plaque morphology: substudy results of the ANTIQUE study
    David Pakizer, Anna Vybíralová, Tomáš Jonszta, Martin Roubec, Michal Král, Vendelín Chovanec, Roman Herzig, Tomáš Heryán, David Školoudík
    Frontiers in Neurology, 2023
  • Differentiating between stable and progressive carotid atherosclerotic plaques from in-vivo ultrasound images using texture descriptors
    Martin Kostelansky, Ana Manzano Rodriguez, Jan Kybic, Miroslav Hekrdla, Ondrej Dvorsky, Jiri Kozel, Patricie Baurova, David Pakizer, David Skoloudik
    Proceedings of SPIE the International Society for Optical Engineering, 2021

RECENT SCHOLAR PUBLICATIONS

  • ABSTRACT NUMBER: ESOC2026A2439 USE OF POINT-OF-CARE AND INTERVENTIONAL ULTRASOUND MODULES DEVELOPED FOR HYBRID MOBILE STROKE UNITS
    R Licenik, D Pakizer, M Huncovsky, R Mikulik, D Pfeifer, O Volny, P Janik, ...
    European Stroke Journal 11 (Suppl 1), i979 , 2026
    2026
  • ABSTRACT NUMBER: ESOC2026A1232 CAROTID ATHEROSCLEROTIC PLAQUE WIDTH AND PLAQUE PROGRESSION AS MARKERS FOR RISK OF DEATH
    D Skoloudik, D Pakizer, I Szegedi, D Netuka
    European Stroke Journal 11 (Suppl 1), i347 , 2026
    2026
  • ABSTRACT NUMBER: ESOC2026A1202 PREVALENCE OF CAROTID WEB IN PATIENTS WITH CAROTID ATHEROSCLEROSIS AND 10-YEAR RISK OF STROKE: POST-HOC ANALYSIS OF ANTIQUE STUDY
    I Szegedi, D Školoudík, D Pakizer
    European Stroke Journal 11 (Suppl 1), i342 , 2026
    2026
  • ABSTRACT NUMBER: ESOC2026LB218 IMPACT OF NIHSS ON ENDOVASCULAR TREATMENT FOR ISOLATED CERVICAL INTERNAL CAROTID ARTERY OCCLUSION: A SECONDARY ANALYSIS OF THE ETIICA STUDY
    JP Marto, C Riegler, P Gebert, T Reiff, M Sykora, M Wiącek, D Pakizer, ...
    European Stroke Journal 11 (Supplement_1), i1029-i1030 , 2026
    2026
  • ABSTRACT NUMBER: ESOC2026A1050 NON-INVASIVELY DETECTED CAROTID PLAQUE CHARACTERISTICS ASSOCIATED WITH CEREBROVASCULAR EVENTS IN SYMPTOMATIC PATIENTS: A META-ANALYSIS
    D Pakizer, I Szegedi, F Strouhal, N Attila, P Michel, D Školoudík, ...
    European Stroke Journal 11 (Supplement_1), i305-i305 , 2026
    2026
  • ABSTRACT NUMBER: ESOC2026A1240 HEMODYNAMIC PHANTOM FOR TESTING MICROEMBOLI DETECTION BY TRANSCRANIAL DOPPLER
    D Skoloudik, R Matejka, D Pakizer, I Szegedi, A Skoloudik, D Netuka
    European Stroke Journal 11 (Supplement_1), i348-i349 , 2026
    2026
  • Expanding the stroke risk paradigm: Left atrial size as a trigger for preventive action
    D Pakizer, D Školoudík
    European Journal of Internal Medicine , 2026
    2026
  • Contrast-Associated Acute Kidney Injury After Thrombectomy for Ischemic Stroke: Prognostic Impact and CAN-REST Predictive Score
    G Schwarz, A Cascio Rizzo, G Ambler, P Wrona, A Slowik, S Kotas, ...
    Neurology 106 (6), e214655 , 2026
    2026
  • Carotid Endarterectomy Randomized Trials: Overview
    D Pakizer, D Školoudík
    Surgical and Interventional Treatment of Cerebral Ischemia: Basic Science to … , 2026
    2026
  • Emergent Carotid Stenting During Endovascular Therapy for Isolated Cervical Internal Carotid Artery Occlusion
    C Riegler, JP Marto, P Gebert, T Reiff, M Sykora, M Wiącek, D Pakizer, ...
    Journal of Stroke 28 (1), 160-171 , 2026
    2026
  • THE INFLUENCE OF CAROTID PLAQUE MORPHOLOGY ON ISCHEMIC STROKE SEVERITY AND PATIENT OUTCOMES
    D Pakizer, K Stejskalikova, D Salounova, D Skoloudik
    INTERNATIONAL JOURNAL OF STROKE 20 (2_ SUPPL) , 2025
    2025
  • PREHOSPITAL HYBRID MOBILE STROKE UNIT FOR ACUTE NEUROEMERGENCY PATIENTS IN RURAL AND MOUNTAINOUS REGIONS OF CZECHIA
    D Pakizer, R Licenik
    INTERNATIONAL JOURNAL OF STROKE 20 (2_ SUPPL) , 2025
    2025
  • Endovascular treatment for isolated cervical internal carotid artery occlusion: ETIICA study
    JP Marto, C Riegler, P Gebert, T Reiff, M Sykora, M Wiącek, D Pakizer, ...
    European stroke journal 10 (3), 694-704 , 2025
    2025
    Citations: 6
  • Histologically verified carotid plaque characteristics by ultrasound: A diagnostic accuracy systematic review
    D Pakizer, J Kozel, J Elmers, J Feber, P Michel, D Školoudík, G Sirimarco
    Ultrasound in Medicine & Biology , 2025
    2025
    Citations: 4
  • A comparative study between CT angiography and flow parameters in hemodynamic phantom of carotid stenosis evaluated by duplex sonography
    A Seidlová, N Svoboda, R Voldřich, P Kešnerová, R Matějka, D Pakizer, ...
    3D Printing in Medicine 11 (1), 29 , 2025
    2025
    Citations: 1
  • Non-invasive imaging of individual histological carotid plaque characteristics: A diagnostic accuracy meta-analysis
    D Pakizer, P Taffé, J Kozel, J Elmers, J Feber, V Dunet, P Michel, ...
    Atherosclerosis, 120391 , 2025
    2025
    Citations: 6
  • Carotid plaque characteristics by computed Tomography: A diagnostic accuracy systematic review
    D Pakizer, J Kozel, J Elmers, J Feber, V Dunet, P Michel, D Školoudík, ...
    IJC Heart & Vasculature 58, 101656 , 2025
    2025
    Citations: 7
  • Sonolysis during carotid endarterectomy: randomised controlled trial
    D Školoudík, T Hrbáč, M Kovář, V Beneš, J Fiedler, M Branca, JB Rossel, ...
    bmj 388 , 2025
    2025
    Citations: 6
  • Diagnostics accuracy of magnetic resonance imaging in detection of atherosclerotic plaque characteristics in carotid arteries compared to histology: a systematic review
    D Pakizer, J Kozel, J Elmers, J Feber, P Michel, D Školoudík, G Sirimarco
    Journal of Magnetic Resonance Imaging 61 (3), 1067-1093 , 2025
    2025
    Citations: 20
  • Extracranial carotid plaque calcification and its association with risk factors for cerebrovascular events: insights from the ANTIQUE study
    D Pakizer, D Šalounová, D Školoudík
    Frontiers in Neurology 16, 1532883 , 2025
    2025
    Citations: 3

MOST CITED SCHOLAR PUBLICATIONS

  • Diagnostics accuracy of magnetic resonance imaging in detection of atherosclerotic plaque characteristics in carotid arteries compared to histology: a systematic review
    D Pakizer, J Kozel, J Elmers, J Feber, P Michel, D Školoudík, G Sirimarco
    Journal of Magnetic Resonance Imaging 61 (3), 1067-1093 , 2025
    2025
    Citations: 20
  • Diagnostic accuracy of carotid plaque instability by noninvasive imaging: a systematic review and meta-analysis
    D Pakizer, J Kozel, P Taffé, J Elmers, J Feber, P Michel, D Školoudík, ...
    European Heart Journal-Cardiovascular Imaging 25 (10), 1325-1335 , 2024
    2024
    Citations: 20
  • Comparison of carotid endarterectomy and repeated carotid angioplasty and stenting for in-stent restenosis (CERCAS trial): a randomised study
    T Hrbáč, J Fiedler, V Procházka, T Jonszta, M Roubec, D Pakizer, ...
    Stroke and vascular neurology 8 (5) , 2023
    2023
    Citations: 16
  • Peak systolic velocity ratio for evaluation of internal carotid artery stenosis correlated with plaque morphology: substudy results of the ANTIQUE study
    D Pakizer, A Vybíralová, T Jonszta, M Roubec, M Král, V Chovanec, ...
    Frontiers in Neurology 14, 1206483 , 2023
    2023
    Citations: 9
  • Carotid plaque characteristics by computed Tomography: A diagnostic accuracy systematic review
    D Pakizer, J Kozel, J Elmers, J Feber, V Dunet, P Michel, D Školoudík, ...
    IJC Heart & Vasculature 58, 101656 , 2025
    2025
    Citations: 7
  • Endovascular treatment for isolated cervical internal carotid artery occlusion: ETIICA study
    JP Marto, C Riegler, P Gebert, T Reiff, M Sykora, M Wiącek, D Pakizer, ...
    European stroke journal 10 (3), 694-704 , 2025
    2025
    Citations: 6
  • Non-invasive imaging of individual histological carotid plaque characteristics: A diagnostic accuracy meta-analysis
    D Pakizer, P Taffé, J Kozel, J Elmers, J Feber, V Dunet, P Michel, ...
    Atherosclerosis, 120391 , 2025
    2025
    Citations: 6
  • Sonolysis during carotid endarterectomy: randomised controlled trial
    D Školoudík, T Hrbáč, M Kovář, V Beneš, J Fiedler, M Branca, JB Rossel, ...
    bmj 388 , 2025
    2025
    Citations: 6
  • Search strategies related to: sensitivity and specificity of atherosclerotic plaque components in carotid arteries detectable by CT, MRI, PET, and sonography–Comparison with …
    D Pakizer, G Sirimarco, J Elmers, P Michel, D Školoudík
    Zenodo , 2022
    2022
    Citations: 6
  • Histologically verified carotid plaque characteristics by ultrasound: A diagnostic accuracy systematic review
    D Pakizer, J Kozel, J Elmers, J Feber, P Michel, D Školoudík, G Sirimarco
    Ultrasound in Medicine & Biology , 2025
    2025
    Citations: 4
  • MRI-and CT-derived carotid plaque characteristics and stroke: Insights from the ANTIQUE study
    D Pakizer, D Netuka, T Hrbáč, J Vrána, F Charvát, T Jonszta, P Kešnerová, ...
    Polish Heart Journal (Kardiologia Polska) 83 (3), 277-286 , 2025
    2025
    Citations: 4
  • Changes in cognitive functions after carotid endarterectomy and carotid stenting: a decade-apart comparison
    D Václavík, D Pakizer, T Hrbáč, M Roubec, V Procházka, T Jonszta, ...
    Biomedicines 12 (1), 13 , 2023
    2023
    Citations: 4
  • Differentiating between stable and progressive carotid atherosclerotic plaques from in-vivo ultrasound images using texture descriptors
    M Kostelansky, AM Rodriguez, J Kybic, M Hekrdla, O Dvorsky, J Kozel, ...
    17th International Symposium on Medical Information Processing and Analysis … , 2021
    2021
    Citations: 4
  • Extracranial carotid plaque calcification and its association with risk factors for cerebrovascular events: insights from the ANTIQUE study
    D Pakizer, D Šalounová, D Školoudík
    Frontiers in Neurology 16, 1532883 , 2025
    2025
    Citations: 3
  • Atherosclerotic plaque stability prediction from longitudinal ultrasound images
    J Kybic, D Pakizer, J Kozel, P Michalčová, F Charvát, D Školoudík
    International Workshop on Machine Learning in Medical Imaging, 124-132 , 2024
    2024
    Citations: 2
  • A comparative study between CT angiography and flow parameters in hemodynamic phantom of carotid stenosis evaluated by duplex sonography
    A Seidlová, N Svoboda, R Voldřich, P Kešnerová, R Matějka, D Pakizer, ...
    3D Printing in Medicine 11 (1), 29 , 2025
    2025
    Citations: 1
  • Predikce stability aterosklerotického plátu z transverzálních ultrazvukových obrazů pomocí hlubokého učení.
    J Kybic, D Pakizer, J Kozel, P Michalčová, F Charvát, D Školoudík
    Česká a Slovenská Neurologie a Neurochirurgie 87 (4) , 2024
    2024
    Citations: 1
  • Carotid atherosclerotic plaque stability prediction from transversal ultrasound images using deep learning
    J Kybic, D Pakizer, J Kozel, P Michalčová, F Charvát, D Školoudík
    CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE 87 (4) , 2024
    2024
    Citations: 1
  • Diagnostic accuracy of non-invasive imaging methods in detection of intraplaque hemorrhage in carotid atherosclerotic plaques: A systematic review and meta-analysis
    D Pakizer, J Kozel, P Taffé, J Elmers, J Feber, P Michel, D Skoloudik, ...
    Journal of the Neurological Sciences 455 , 2023
    2023
    Citations: 1
  • Risk of MRI-detected cerebral infarction and vascular events after carotid endarterectomy and carotid stenting one decade apart
    T Hrbáč, M Roubec, V Procházka, T Jonszta, D Pakizer, T Heryán, ...
    British Journal of Surgery 110 (8), 987-988 , 2023
    2023
    Citations: 1