Ilona Procházková

PhD study, the Laboratory of Molecular Biology of Bacterial Pathogens headed by Prof. Peter Šebo, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, and The University of Chemistry and Technology, Prague
Dissertation thesis - Role of the RNA chaperone Hfq and small non-coding RNAs in Bordetella pertussis virulence
Diploma, the Laboratory of Molecular Biology of Bacterial Pathogens headed by Prof. Peter Šebo, Institute of Microbiology of the Academy of Sciences of the Czech Republic, Prague, and The University of Chemistry and Technology, Prague
Diploma thesis - Detection of memory T cells specific response to stimulation by mycobacterial antigens

 Post-transcriptional regulation in Bacteria
 Role of the small regulatory RNAs and RNA chaperone Hfq in virulence
 Molecular pathogenesis of whooping cough
 Host-pathogen interactions

Keidel K., Amman F., Bibova I., Drzmisek J., Benes V., Hot D., Vecerek B. Signal transduction-dependent small regulatory RNA is involved in glutamate metabolism of the human pathogen Bordetella pertussis. RNA 2018, 24: 1530-1541
Amman F., D'Halluin A., Antoine R., Huot L., Bibova I., Keidel K., Slupek S., Bouquet P., Coutte L., Caboche S., Locht C., Vecerek B., Hot D. Primary transcriptome analysis reveals importance of IS elements for the shaping of the transcriptional landscape of Bordetella pertussis. RNA Biol. 2018, 15: 967–975
Skopova K, Tomalova B, Kanchev I, Rossmann P, Svedova M, Adkins I, Bibova I, Tomala J, Masin J, Guiso N, Osicka R, Sedlacek R, Kovar M, Sebo P. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis. Infect Immun. 2017, 85(6):e00937-16. doi: 10.1128/
Seydlova G., Beranova J., Bibova I., Dienstbier A., Drzmisek J., Masin J., Fiser R., Konopasek I., Vecerek B. The extent of the temperature-induced membrane remodeling in two closely related Bordetella species reflects their adaptation to diverse environmental niches. J Biol Chem 2017, 292:8048-8058
Bumba L, Masin J, Macek P, Wald T, Motlova L, Bibova I, Klimova N, Bednarova L, Veverka V, Kachala M, Svergun DI, Barinka C, Sebo P. Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts. Mol Cell. 2016, 62(1):47-62
Cerny O, Kamanova J, Mas