Ashkan Bigham got his PhD in Materials Science and Engineering from the University of Naples Federico II. He is currently a Research Associate at the Institute of Polymers, Composites, and Biomaterials (IPCB) of the National Research Council of Italy (CNR), Italy. He was a research fellow at IPCB and the Institute of Biochemistry and Cell Biology (IBBC, CNR) from 2020 to 2022 developing theragenerative (therapeutic + regenerative) biomaterials for cancer therapy and regeneration. His current scientific interests include the design and synthesis of multifunctional biomaterials and biocomposites for biomedical applications.
His Professional and Scientific activity comprises: More than 70 scientific publications including original research papers, reviews, and book chapters in high-impact factor and prestigious journals and publishers including Chemical Society Reviews, Advanced Materials, Advanced Science, Small, Bioactive Materials, etc., and more than 10 presentations at international
EDUCATION
PhD in Materials Science from University of Naples Federico II
3D-Printed Polycaprolactone/Gelatin Scaffolds Reinforced with Nano-Strontium Carbonate and Bioactive Glass for Enhanced Osteogenic Performance N Keihani, M Babaei, A Bigham, F Amiri, SA Poursamar, MR Nilforoushan, ... Journal of Polymers and the Environment 34 (5), 117 , 2026 2026
Zinc-Containing Biomaterials for Bone Disease Therapy and Tissue Repair: Design Principles, Mechanistic Insights, and Translational Pathways I Zare, MS Far, S Tajabadi, Z Jafari, BS Heidari, Y Esmaeili, SM Davachi, ... Biomaterials, 124200 , 2026 2026
Black phosphorus in theragenerative medicine: a multi-organ perspective on disease modulation and tissue repair A Bigham, A Mariano, AR Boccaccini, L Ambrosio, MG Raucci Bioactive Materials 58, 422-471 , 2026 2026 Citations: 2
The MCM/Lys-Cys Nanodevices for the Efficient Gene Delivery: An Approach Towards MCP1 Gene manipulation using CRISPR technology A Rahimi, I Rahimmanesh, N Abedpoor, M Boshtam, E Bidram, ... Colloids and Surfaces B: Biointerfaces 260, 115377 , 2026 2026
Hybrid and Composite Nanofibrous Materials for Wound Healing Applications S Homaeigohar, JA Roether, AR Boccaccini Royal Society of Chemistry , 2025 2025 Citations: 1
Composite and Hybrid Conductive Nanofibers for Accelerated Wound Healing MS Far, S Tajabadi, MG Raucci, L Ambrosio, A Bigham 2025
Fabrication and characterization of 3D porous microtube Bioglass 58S using a sacrificial Polyethersulfone template for bone tissue engineering Z Emami, A Bigham, MA Bahri, B Latifi, M Mehrazin, SA Poursamar, ... Ceramics International , 2025 2025
A MULTIFUNCTIONAL 3D-PRINTED SCAFFOLD WITH THERAPEUTIC AND REGENERATIVE POTENTIAL FOR BONE CANCER THERAPY AND TISSUE REGENERATION A Bigham, A Mariano, X Yang, X Zhang, MG Raucci, L Ambrosio Orthopaedic Proceedings 107 (SUPP_8), 1-1 , 2025 2025
Advanced nanofibers for water treatment: unveiling the potential of electrospun polyacrylonitrile membranes M Shakiba, M Faraji, S Jouybar, A Foroozandeh, A Bigham, M Abdouss, ... Environmental Research 276, 121403 , 2025 2025 Citations: 15
The Therapeutic Potential of Berberine in Lung Cancer Z Jafari, S Honarmand, Z Abbasirad, S Sadeghi, A Bigham Archiv der Pharmazie 358 (6), e70013 , 2025 2025 Citations: 4
Inspired by nature: Bioinspired and biomimetic photocatalysts for biomedical applications A Bigham, A Zarepour, M Safarkhani, YS Huh, A Khosravi, N Rabiee, ... Nano Materials Science 7 (1), 1-23 , 2025 2025 Citations: 33
Black phosphorus-based nanoplatforms for cancer therapy: chemistry, design, biological and therapeutic behaviors A Bigham, M Serrano-Ruiz, M Caporali, I Fasolino, M Peruzzini, ... Chemical Society Reviews 54 (2), 827-897 , 2025 2025 Citations: 48
Microneedle patches: a new vantage point for diabetic wound treatments A Bigham, A Zarepour, A Khosravi, S Iravani, A Zarrabi Biomaterials Science 13 (2), 379-407 , 2025 2025 Citations: 18
Nanosystems for targeted drug Delivery: Innovations and challenges in overcoming the Blood-Brain barrier for neurodegenerative disease and cancer therapy N Rafati, A Zarepour, A Bigham, A Khosravi, H Naderi-Manesh, S Iravani, ... International Journal of Pharmaceutics 666, 124800 , 2024 2024 Citations: 42
3D printed polycaprolactone/gelatin/ordered mesoporous calcium magnesium silicate nanocomposite scaffold for bone tissue regeneration Z Mirzavandi, SA Poursamar, F Amiri, A Bigham, M Rafienia Journal of Materials Science: Materials in Medicine 35 (1), 58 , 2024 2024 Citations: 15
Micelle-engineered nanoplatforms for precision oncology W Gao, A Bigham, M Ghomi, A Zarrabi, N Rabiee, MR Saeb, YN Ertas, ... Chemical Engineering Journal 495, 153438 , 2024 2024 Citations: 31
Sustainable nanomaterials for precision medicine in cancer therapy A Bigham, A Zarepour, A Khosravi, S Iravani, A Zarrabi Materials Today Sustainability 27, 100865 , 2024 2024 Citations: 19
A bi‐functional nanofibrous composite membrane for wound healing applications M Shakiba, M Pourmadadi, SM Hosseini, A Bigham, E Rahmani, ... Archiv der Pharmazie 357 (8), 2400001 , 2024 2024 Citations: 15
MOFs and MOF‐based composites as next‐generation materials for wound healing and dressings A Bigham, N Islami, A Khosravi, A Zarepour, S Iravani, A Zarrabi Small 20 (30), 2311903 , 2024 2024 Citations: 124
Solid lipid nanoparticles and their application in the treatment of bacterial infectious diseases MR Arabestani, A Bigham, F Kamarehei, M Dini, F Gorjikhah, A Shariati, ... Biomedicine & Pharmacotherapy 174, 116433 , 2024 2024 Citations: 70
MOST CITED SCHOLAR PUBLICATIONS
Nylon—A material introduction and overview for biomedical applications M Shakiba, E Rezvani Ghomi, F Khosravi, S Jouybar, A Bigham, M Zare, ... Polymers for advanced technologies 32 (9), 3368-3383 , 2021 2021 Citations: 291
Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches M Ashrafizadeh, M Delfi, A Zarrabi, A Bigham, E Sharifi, N Rabiee, ... Journal of controlled release 351, 50-80 , 2022 2022 Citations: 237
Advances in tannic acid-incorporated biomaterials: Infection treatment, regenerative medicine, cancer therapy, and biosensing A Bigham, V Rahimkhoei, P Abasian, M Delfi, J Naderi, M Ghomi, ... Chemical Engineering Journal 432, 134146 , 2022 2022 Citations: 235
pHEMA: An overview for biomedical applications M Zare, A Bigham, M Zare, H Luo, E Rezvani Ghomi, S Ramakrishna International journal of molecular sciences 22 (12), 6376 , 2021 2021 Citations: 226
(Nano) platforms in breast cancer therapy: drug/gene delivery, advanced nanocarriers and immunotherapy M Ashrafizadeh, A Zarrabi, A Bigham, A Taheriazam, Y Saghari, S Mirzaei, ... Medicinal Research Reviews 43 (6), 2115-2176 , 2023 2023 Citations: 196
Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation E Sharifi, A Bigham, S Yousefiasl, M Trovato, M Ghomi, Y Esmaeili, ... Advanced Science 9 (2), 2102678 , 2022 2022 Citations: 154
Electrophoretic-deposited hydroxyapatite-copper nanocomposite as an antibacterial coating for biomedical applications M Hadidi, A Bigham, E Saebnoori, SA Hassanzadeh-Tabrizi, S Rahmati, ... Surface and Coatings Technology 321, 171-179 , 2017 2017 Citations: 154
In situ microemulsion synthesis of hydroxyapatite-MgFe2O4 nanocomposite as a magnetic drug delivery system F Foroughi, SA Hassanzadeh-Tabrizi, A Bigham Materials Science and Engineering: C 68, 774-779 , 2016 2016 Citations: 148
MOFs and MOF‐based composites as next‐generation materials for wound healing and dressings A Bigham, N Islami, A Khosravi, A Zarepour, S Iravani, A Zarrabi Small 20 (30), 2311903 , 2024 2024 Citations: 124
The journey of multifunctional bone scaffolds fabricated from traditional toward modern techniques A Bigham, F Foroughi, E Rezvani Ghomi, M Rafienia, RE Neisiany, ... Bio-Design and Manufacturing 3 (4), 281-306 , 2020 2020 Citations: 112
Chitosan‐based nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy M Ashrafizadeh, K Hushmandi, S Mirzaei, S Bokaie, A Bigham, ... Bioengineering & Translational Medicine 8 (1), e10325 , 2023 2023 Citations: 111
Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy AD Dey, A Bigham, Y Esmaeili, M Ashrafizadeh, FD Moghaddam, SC Tan, ... Seminars in Cancer Biology 86, 396-419 , 2022 2022 Citations: 92
Solvothermal synthesis of magnetic spinel ferrites M Rafienia, A Bigham, SA Hassanzadeh-Tabrizi Journal of Medical Signals & Sensors 8 (2), 108-118 , 2018 2018 Citations: 87
Nanotechnology-abetted astaxanthin formulations in multimodel therapeutic and biomedical applications Z Jafari, A Bigham, S Sadeghi, SM Dehdashti, N Rabiee, A Abedivash, ... Journal of Medicinal Chemistry 65 (1), 2-36 , 2021 2021 Citations: 86
Mesoporous silica@ chitosan@ gold nanoparticles as “on/off” optical biosensor and pH-sensitive theranostic platform against cancer Y Esmaeili, M Khavani, A Bigham, A Sanati, E Bidram, L Shariati, ... International journal of biological macromolecules 202, 241-255 , 2022 2022 Citations: 80
Biosynthesized nanomaterials with antioxidant and antimicrobial properties G Heidari, M Hassanpour, F Nejaddehbashi, MR Sarfjoo, S Yousefiasl, ... Materials Chemistry Horizons 1 (1), 35-48 , 2022 2022 Citations: 74
Nanostructured magnetic Mg2SiO4-CoFe2O4 composite scaffold with multiple capabilities for bone tissue regeneration A Bigham, AH Aghajanian, S Behzadzadeh, Z Sokhani, S Shojaei, ... Materials Science and Engineering: C 99, 83-95 , 2019 2019 Citations: 74
Multifunctional nanoporous magnetic zinc silicate-ZnFe2O4 core-shell composite for bone tissue engineering applications A Bigham, F Foroughi, M Motamedi, M Rafienia Ceramics International 44 (10), 11798-11806 , 2018 2018 Citations: 71
Solid lipid nanoparticles and their application in the treatment of bacterial infectious diseases MR Arabestani, A Bigham, F Kamarehei, M Dini, F Gorjikhah, A Shariati, ... Biomedicine & Pharmacotherapy 174, 116433 , 2024 2024 Citations: 70
Zn-substituted Mg2SiO4 nanoparticles-incorporated PCL-silk fibroin composite scaffold: A multifunctional platform towards bone tissue regeneration A Bigham, AOM Salehi, M Rafienia, MR Salamat, S Rahmati, MG Raucci, ... Materials Science and Engineering: C 127, 112242 , 2021 2021 Citations: 66
