Jan Malik

Scopus Publications

Blood biomarkers for the prediction of outcome after cardiac arrest: an international prospective observational study within the Targeted Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial
Marion Moseby-Knappe, Helena Levin, Susann Ullén, Henrik Zetterberg, Kaj Blennow, et al.
Lancet Respiratory Medicine, 2026
How to Define High-Flow Arteriovenous Fistula? Comment on Kim et al. Hemodynamic Adaptation and Cardiac Effects of High-Flow Arteriovenous Access in Hemodialysis Patients: A Prospective Study. J. Clin. Med. 2025, 14, 4556
Jan Malik, Anna Valerianova, Kristina Buryskova Salajova, Pavel Michalek
Journal of Clinical Medicine, 2026
We have read the manuscript by Yaeni Kim et al [...]
Classifications of haemodialysis vascular access-induced limb ischaemia
Katerina Lawrie, Stephen O’Neill, Jan Malik, Peter Balaz, Michael Corr, et al.
Journal of Vascular Access, 2026
Vascular access-induced limb ischaemia is a potentially severe complication. A classification system for clinical assessment and treatment would be a useful clinical tool for standardising management. There are several classifications described in the current literature using inconsistent terminology. The aim of this review is to identify all the reported classification systems of vascular access-induced limb ischaemia and to present a comprehensive summary. PubMed, Scopus, Web of Science, Google Scholar and the ClinicalTrials.gov registry were searched from inception to the 17th of October 2024. All articles containing newly proposed classifications regarding haemodialysis vascular access were eligible. There were no restrictions to the full text’s language or the type of study. The classifications were evaluated using a modified Buchbinder’s classification critical appraisal tool. From 4694 screened papers, 59 full-text papers were retrieved, and eight articles contained classifications based only on the severity of vascular access-induced limb ischaemia. According to the modified Buchbinder critical appraisal, the classifications identified were overall good quality. The systems are all based on clinical symptoms but use inconsistent terminology and do not consider various aetiologies. We present a summary and propose a unified classification based on the anatomical location of the pathology, which leads to high- or low-flow ischaemia, along with a suitable therapeutic approach for each type.
Improvement of the left atrial systolic function after a surgical reduction of the high flow arteriovenous fistula
Vaclav Lejsek, Anna Valerianova, Kristyna Michalickova, Kristina Buryskova Salajova, Marcela Slavikova, et al.
Frontiers in Medicine, 2026
Background High-output heart failure (HOHF) is a distinct cardiac complication in end-stage kidney disease (ESKD) patients with high-flow arteriovenous fistulae (AVFs). While AVF flow reduction improves hemodynamics and left atrial (LA) volume, its effect on LA systolic function remains unclear. Objective To evaluate changes in left atrial systolic function and left ventricular (LV) filling pressures following surgical AVF flow reduction in haemodialysis patients with high-flow fistulae. Methods In this prospective, single-centre interventional study, 28 ESKD patients (mean age 63 ± 15 years) with high-flow AVFs (&gt;1,500 mL/min) and clinical heart failure (NYHA ≥ II) underwent surgical AVF flow reduction. Echocardiographic assessments were performed before and 6 weeks after intervention. LA ejection fraction (LAEF) and LV filling pressures (E/e′ ratio) were determined from digitally stored imaging data. Results Surgical intervention reduced AVF flow by approximately 50% [2,525 [1,388] to 1,250 [700] mL/min, p = 0.00006]. LA volume index decreased significantly (44.7 ± 17.3 to 38.5 ± 15.4 mL/m 2 , p = 0.01), accompanied by an improvement in LAEF (49.6 ± 14.9% to 53.2 ± 13.5%, p = 0.046). Dyspnoea improved or resolved in all patients. Baseline LAEF correlated negatively with age, LA volume index, and NYHA class, but no independent predictors of post-operative LAEF improvement were identified. Conclusions In patients with high-flow AVF–associated HOHF, surgical AVF flow reduction leads to a significant improvement in LA systolic function alongside decreased LA volume. These findings suggest partial reversibility of atrial remodeling induced by chronic hyperkinetic circulation and highlight the potential cardiovascular benefits of AVF flow optimization in selected dialysis patients.
Correction: Improvement of the left atrial systolic function after a surgical reduction of the high flow arteriovenous fistula (Frontiers in Medicine, (2026), 12, (1732862), 10.3389/fmed.2025.1732862)
Vaclav Lejsek, Anna Valerianova, Kristyna Michalickova, Kristina Buryskova Salajova, Marcela Slavikova, et al.
Frontiers in Medicine, 2026
Corrigendum: Vascular Access Management After Kidney Transplantation Position Paper on Behalf of the Vascular Access Society and the European Kidney Transplant Association (Transplant International, (2025), 38, (14712), 10.3389/ti.2025.14712)
Barış Akin, Tamara K. Jemcov, David Cucchiari, Jan Malik, Gavin J. Pettigrew, et al.
Transplant International, 2026
Negative impact of very mild volume overload on the heart function in patients on chronic hemodialysis
Kristyna Michalickova, Jan Malik, Anna Valerianova, Zdenka Hruskova, Vladimira Bednarova, et al.
Renal Failure, 2026
Lower cholesterol level on admission predicts poor outcome after prolonged cardiac arrest
Jan Malik, Anna Valerianova, Tomas Janota, Jana Smalcova, Nikol Kubinova, et al.
Scientific Reports, 2025
Using ultrasound in preoperative mapping and surveillance of arteriovenous grafts for haemodialysis improves patency rates: Single-centre experience
Julia Jarosciakova, Petr Utikal, Jan Malik, Jana Janeckova
Journal of Vascular Access, 2025
Background: This study aimed to evaluate patency outcomes of arteriovenous grafts (AVGs) before and after using Duplex doppler ultrasonography (DUS) in preoperative mapping and surveillance of AVG. Methods: In this single-centre, retrospective cohort study 212 patients receiving AVGs from January 2009 to December 2022 were included. In group 1, the creation of AVG as well as screening was based on physical examination alone. In contrast, DUS was used in the preoperative mapping and surveillance of AVG in group 2. The patients also received sulodexide as supplemental medication. Outcomes included primary and secondary patency. The Mann-Whitney U-test was used to compare the differences between groups in number of thrombectomies and preemptive percutaneous transluminal angioplasties (PTAs). Results: Group 1 included 90 AVGs. The mean follow-up time was 333 days (range: 1–1230 days, standard deviation: 318 days). The primary and secondary graft patency rates were 13.3%, 62.2% at 6 months; 2.2%, 52.1% at 12 months; 0%, 44.3% at 24 months and 0%, 44.3% at 36 months respectively. During the 7-year surveillance of AVG, significantly more thrombectomies were performed than preemptive PTA ( p < 0.0001). Group 2 included 122 AVGs. The mean follow-up time was 584 days (range: 1–2040 days, standard deviation: 463 days). The primary and secondary graft patency rates were 54.9%, 95.9% at 6 months; 29.5%, 77.8% at 12 months; and 9.8%, 56.5% at 24 months; 2.5%, 47.1% at 36 months respectively. The primary and secondary graft patency was significantly longer ( p < 0.0001, p = 0.002). During the 7-year surveillance of AVG there were significantly more preemptive PTAs performed ( p = 0.0004). Conclusions: The primary and secondary patency of AVG were significantly improved after using DUS in preoperative mapping and surveillance. DUS surveillance led to a decrease in AVG occlusion. A potential positive effect of sulodexide on patency rate of AVG needs more research.
The significance of possible non-occlusive mesenteric ischemia in relation to neurological outcomes in patients with refractory cardiac arrest – Secondary analysis of the Prague OHCA study
Jana Smalcova, Jacky Suen, Michal Huptych, Ondrej Franek, Petra Kavalkova, et al.
Resuscitation, 2025
Reasons for death in patients receiving ECPR for refractory out-of-hospital cardiac arrest
Klaudia Farkasovska, Daniel Rob, Marie Dacev, Petra Kavalkova, Jaromir Macoun, et al.
Resuscitation, 2025
Intestinal fatty acid-binding protein as a marker of prognosis and non-occlusive mesenteric ischemia in refractory cardiac arrest patients: a pilot study
Jana Smalcova, Lahoda Helena Brodska, Jacky Suen, Zdislava Vanickova, Petra Kavalkova, et al.
Resuscitation Plus, 2025
Management of vascular access inflow-outflow imbalance: A bimodal approach
Gerald A Beathard, William C Jennings, Jan Malik, Haimanot Wasse, Bart L Dolmatch, et al.
Journal of Vascular Access, 2025
Nephrology Partnership for Advancing Technology in Healthcare (N-PATH) Erasmus+ project: The Renal Expert in Vascular Access (REVAC) module
Carlo Lomonte, Jose Ibeas, Panagiotis Kitrou, Antonio Giusto, Marta Baratto, et al.
Journal of Vascular Access, 2025
Impact of routine extracorporeal cardiopulmonary resuscitation service on the availability of donor organs
Jana Smalcova, Petra Krupickova, Eva Pokorna, Ondrej Franek, Michal Huptych, et al.
Journal of Heart and Lung Transplantation, 2025
Classifications of haemodialysis vascular access stenosis: a scoping review
Katerina Lawrie, Stephen O’Neill, Jan Malik, Libor Janousek, Michael Corr, et al.
BMJ Open, 2025
First Real-Time Imaging of Acute Effects of Arteriovenous Fistula on Regional Distribution of Pulmonary Perfusion in a Novel Porcine Model
J Borges, A Valerianova, L Tejkl, J Malik, M Mlček, et al.
Physiological Research, 2025
Translumbar access to the inferior vena cava – rescue option for insertion of a central venous catheter
P Michálek, T Brožek, J Kaván, L Forejtová, M Novák, et al.
Anesteziologie A Intenzivni Medicina, 2025
Vascular Access Management After Kidney Transplantation Position Paper on Behalf of the Vascular Access Society and the European Kidney Transplant Association
Barış Akin, Tamara K. Jemcov, David Cucchiari, Jan Malik, Gavin J. Pettigrew, et al.
Transplant International, 2025
Right ventricular-pulmonary arterial coupling and pulmonary hypertension in hemodialysis: insights into structural cardiac changes and clinical implications
Kristina Buryskova Salajova, Jan Malik, Lucie Kaiserova, Zuzana Hladinova, Zdenka Hruskova, et al.
Renal Failure, 2025
Vascular access ultrasonography: The risk of simplification
Cora de Bont, Jan Malik
Journal of Vascular Access, 2024
Non-invasively assessed haemodynamics in patients with high flow arteriovenous fistula and high output cardiac failure
Kristína Burýšková Salajová, Jan Malík, Anna Valeriánová
Esc Heart Failure, 2024
Increased Cardiovascular Risk in Young Patients with CKD and the Role of Lipid-Lowering Therapy
Vojtech Kratky, Anna Valerianova, Zdenka Hruskova, Vladimir Tesar, Jan Malik
Current Atherosclerosis Reports, 2024
Cardiorenal Syndromes and Their Role in Water and Sodium Homeostasis
K Buryskova Salajova, J Malik, A Valerianova
Physiological Research, 2024
CZecking heart failure in patients with advanced chronic kidney disease (Czech HF-CKD): Study protocol
Jan Malik, Anna Valerianova, Satu Sinikka Pesickova, Zdenka Hruskova, Vladimira Bednarova, et al.
Journal of Vascular Access, 2024

Jan Malik

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Scopus Publications