Silvestre Garcia de la Puente
@pediatria.gob.mx
Instituto Nacional de Pediatría. Departamento de Metodología de la Investigación
Jefe de Departamento
@pediatria.gob.mx
Instituto Nacional de Pediatría. Departamento de Metodología de la Investigación
Jefe de Departamento
Objective. To describe the complete blood count (CBC) values of pediatric patients with Down syndrome and report the most common non-malignant hematological alterations. Materials and Methods. The analysis includes data from 450 patients with Down syndrome, aged 0-18 years, whose clinical charts included CBC panel results for the period January 2008 through March 2018. Results. A total of 3438 CBC panels were analyzed with descriptive statistics to find the values and statistical dispersion of the major indicators, with percentiles, and reported separately by sex and age group. The most common non-malignant hematological alterations found were macrocytic anemia, leukopenia, lymphopenia, and thrombocytosis. There were differences in values in all three series. Conclusions. The CBC panels and hematological alterations are summarized for patients with Down syndrome.
