Internal Medicine, Nephrology, Hypertension, Infectlon, Public Health,
FUTURE PROJECTS
Research about Kdney Disease and COVID-19
Applications Invited
35
Scopus Publications
656
Scholar Citations
14
Scholar h-index
20
Scholar i10-index
Scopus Publications
Garcinia forbesii King leaf extract protects against renal tubular injury in ischemia-reperfusion injury via IL-18 and oxidative stress reduction Azma Rosida, Nia Kania, Mohammad Rudiansyah, Fujiati, Triawanti, Ika Oktaviyanti, Roselina Panghiyangani, Nur Arfian Tropical Journal of Pharmaceutical Research, 2026 Purpose: To evaluate the protective effects of Garcinia forbesii King leaf extract against renal tubular injury induced by Renal ischemia–reperfusion injury (IRI) and to assess its association with inflammatory and oxidative stress markers, including interleukin-18 (IL-18), superoxide dismutase 2 (SOD2), and malondialdehyde (MDA).Methods: Male Wistar rats were subjected to renal IRI and treated with Garcinia forbesii King leaf extract at doses of 2.5, 25, and 250 mg/kg. Renal IL-18 levels, SOD2 expression, serum MDA levels, and histopathological tubular injury scores were evaluated.Results: Renal IL-18 levels were significantly increased in IRI group compared with the sham-operated group. Treatment with Garcinia forbesii King leaf extract at doses of 25 and 250 mg/kg significantly reduced renal IL-18 levels. The medium dose (25 mg/kg) significantly increased renal SOD2 expression and reduced serum MDA levels. Histopathological analysis showed that low- and medium-dose treatments attenuated renal tubular injury, whereas the high dose did not provide additional histological protection.Conclusion: Garcinia forbesii King leaf extract exerts nephroprotective effects against IRI-induced renal injury, likely through modulation of inflammatory responses and oxidative stress.
Symptoms, Ways of Transmission, Prevention, and Treatment of HIV Virus: A Review Amr Ali Mohamed Abdelgawwad El-Sehrawy, Mohammad Rudiansyah, Zahraa Abbas, Mohannad Abdulrazzaq Gati, Batool Ali Ahmed, Mohammad Javad Mohammadi Jundishapur Journal of Chronic Disease Care, 2026 Context: The human immunodeficiency virus (HIV) in humans causes the disease acquired immune deficiency syndrome (AIDS). In the recent decade, one of the main challenges of the health system, dangerous infectious diseases, and a major health problem in the world is AIDS. Objectives: The aim of this narrative review is to investigate the HIV virus. Methods: This narrative review article has been performed using the keywords HIV virus, chronic disease, and AIDS disease, along with their English equivalents, according to different databases including Google Scholar, CINAHL, Web of Science, Scopus, and PubMed from the years 1990 to 2024. A total of 392 articles were retrieved according to these databases. Results: The main symptoms of HIV include fever, lymphadenopathy, fatigue, weight loss, pneumonia, diarrhea, and oral yeast infection. The results of this study showed that AIDS can last from about three years to more than 20 years without any treatment, depending on the strength of the person's immune system. Exposure to infected blood or tissue, sexual contact, and mother-to-child transmission during pregnancy, childbirth, or breastfeeding are the main ways of transmission of the HIV virus. A common misconception about AIDS is that it can be transmitted through daily living with people living with the HIV virus. Based on the results of this study, sex education in schools, regular use of condoms, needle exchange, and drug substitution treatments among injecting drug addicts, using a vaginal gel containing tenofovir immediately before sex, performing accurate tests on blood products, and using up-to-date laboratory equipment in the long term reduce the risk of HIV transmission. Conclusions: This study evaluated the symptoms, ways of transmission, prevention, and treatment of the HIV virus. The main ways of reducing the transmission of HIV include raising awareness of the dangers of HIV and AIDS among people, sex education for young people in schools, efforts to reduce the number of addicts, especially injection drug addicts, reducing high-risk sexual behaviors, and increasing healthcare coverage for patients with the HIV virus.
The effect of resistant dextrin on glucose regulation markers in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials Mohammad Rudiansyah, Dina Akeel Salman, Hardik Doshi, Renuka Jyothi S., Debasish Shit, Swati Sharma, Mehran Nouri BMC Nutrition, 2025 The increasing prevalence of type 2 diabetes (T2D) necessitates greater efforts to find effective therapeutic agents for this complex condition. This study conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of resistant dextrin (RD) supplementation on markers of glucose regulation in patients with T2D. The databases PubMed, Web of Science, Scopus, and the Cochrane Library were searched from inception to March 20, 2025 aiming to identify RCTs evaluating the effect of RD supplementation on fasting blood sugar (FBS), fasting insulin levels, and glycosylated hemoglobin (HbA1c) in patients with T2D. The meta-analysis was conducted using a random-effects model to calculate weighted mean differences (WMDs) and corresponding 95% confidence intervals (95% CI). The quality of the included RCTs was assessed using the Cochrane risk of bias tool. The outcome data was pooled using Stata software, version 11.2. Four RCTs (260 participants) were included in the systematic review and meta-analysis. Meta-analyses indicated that RD supplementation was associated with a significant reduction in HbA1c levels (WMD: -0.30%; 95% CI: -0.56 to -0.03; P = 0.02; I2=0.0%). However, the effect of RD on FBS (WMD: -5.45 mg/dl, 95% CI: -12.38 to 1.93; P = 0.14; I2=55.3%) and fasting insulin levels (Hedges’ g: -0.26; 95% CI: -0.74 to 0.21; P = 0.28; I2=70.4%) was not statistically significant. This systematic review and meta-analysis demonstrated that RD supplementation may effectively lower HbA1c levels in patients with T2D. However, it is crucial to conduct more clinical studies with adequate sample sizes and rigorous methodologies to develop evidence-based treatment guidelines.
Integrating Metabolomics LC-HRMS, and Network Pharmacology of Garcinia forbesii King Leaf Extract, Potential for Treatment of Renal Ischemic Reperfusion Injury Azma Rosida, Nia Kania, Mohammad Rudiansyah, Fujiati Fujiati, Oski Illiandri, Wivina R Devi Tropical Journal of Natural Product Research, 2025 Garcinia forbesii King, locally known as Mundar in South Kalimantan, is rich in xanthone natural compounds recognized for their strong antioxidant and anti-inflammatory activities, which are thought to protect the kidneys from damage. However, the exact biological pathways are not fully understood. This study aimed to identify the bioactive compounds in Garcinia forbesii leaf and explore their potential mechanisms in protecting against kidney injury using a network pharmacology approach. The compounds were detected through liquid chromatography– high resolution mass spectrometry (LC-HRMS), and their chemical structures were represented in SMILES format using PubChem. Drug-likeness properties were assessed using ADMETLab, while potential target genes were identified through the Comparative Toxicogenomics Database and the Similarity Ensemble Approach (SEA). Genes relevant to renal ischemia–reperfusion injury (RIRI) were obtained from GeneCards. The predicted protein targets were then analyzed to determine their associated pathways and functions, and compound–target interaction networks were visualized with Cytoscape 3.10.2. Out of 219 bioactive compounds, 25 showed favorable drug-like properties. The key gene targets identified included TP53, TNF, BCL2, JUN, IL6, RELA, CASP3, IRS1, GSK3B, and NFE2L2. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses showed that the extract primarily influences processes related to apoptosis, gene regulation, and inflammation. The predicted protein targets were largely localized in the cytosol, exosomes, and cytoplasm, suggesting potential modulation of protein–protein interactions. These results point to possible mechanisms by which Garcinia forbesii may protect against kidney injury, strengthening its potential as a nephroprotective candidate.
Comparison of stingless bee honey and silver sulfadiazine on diabetic wound healing in rat models Nanang Miftah Fajari, Agung Pranoto, David Sontani Perdanakusuma, Muhammad Darwin Prenggono, Mohammad Rudiansyah, Hendra Wana Nur'amin, Yulia Syarifa, Nuvita Hasrianti, Imelda Nita Saputri, Muhammad Irawan Afrianto, Annisa Halida Husna Medical Journal of Indonesia, 2025 BACKGROUND Diabetic foot ulcers (DFUs) are a major health concern in Indonesia. Adjuvant therapies may improve healing by avoiding secondary infections, promoting angiogenesis, and supporting oxygen circulation. This aimed to evaluate the effect of stingless bee honey (SBH) from Heterotrigona itama on diabetic wound size in rats (Rattus norvegicus), compared to silver sulfadiazine (SSD). METHODS An experimental study was conducted on 13 diabetic wounds in streptozotocin-induced diabetic rats treated with three types of therapies: SSD (n = 5), pure SBH (n = 5), and SBH with 20% water content (n = 3). The study initially involved 21 rats, but eight died during the diabetes modeling and wound observation phases, presumably due to hyperglycemia. Baseline characteristics did not differ significantly across the groups. RESULTS SBH with 20% water content and pure SBH reduced wound size by 95.1% and 92.1%, outperforming SSD (77.4%), with all therapies showing statistically significant improvement (p<0.05). However, the differences between groups were not statistically significant (p = 0.162). CONCLUSIONS Topically applied SBH is a potential natural therapeutic agent for diabetic wounds, in addition to standard treatment such as SSD.
Herbal therapy in diabetes mellitus: A review Advancements in Life Sciences, 2024
Treatment of pilocarpine-induced epileptic seizures in adult male mice W. K. Abdelbasset, S. A. Jasim, M. Rudiansyah, H. Huldani, R. Margiana, A. T. Jalil, H. J. Mohammad, H. SH. Ridha, G. Yasin Brazilian Journal of Biology, 2024 Epilepsy is one of the most common neurological disorders affecting most social, economic and biological aspects of human life. Most patients with epilepsy have uncontrolled seizures and drug side effects despite the medications. Patients with epilepsy often have problems with attention, memory, and information processing speed, which may be due to seizures, underlying causes, or anticonvulsants. Therefore, improving seizure control and reducing or changing the anti-epileptic drugs can solve these problems, but these problems will not be solved in most cases. In this work, we looked at the effects of pioglitazone, a Peroxisome Proliferator-Activated Receptor agonist used to treat type 2 diabetes, on pilocarpine-induced seizures in mice. The Racine scale was used to classify pilocarpine-induced convulsions. After that, all of the animals were beheaded, and the brain and hippocampus were dissected. Finally, biochemical techniques were used to determine the levels of Malondialdehyde and Catalase activity, as well as Superoxide Dismutase and Glutathione Reductase in the hippocampus. The results of this investigation suggest that pioglitazone's antioxidant action may play a key role in its neuroprotective properties against pilocarpine-induced seizure neuronal damage.
The Nutritional Management of Patients with Continuous Ambulatory Peritoneal Dialysis Acta Medica Indonesiana, 2024
The emerging microbiome-based approaches to IBD therapy: From SCFAs to urolithin A Mohammad Rudiansyah, Saade Abdalkareem Jasim, Bakhadir S. Azizov, Vadim Samusenkov, Walid Kamal Abdelbasset, Ghulam Yasin, Hawraa Jabbar Mohammad, Mohammed Abed Jawad, Trias Mahmudiono, Seyed Reza Hosseini‐Fard, Rasoul Mirzaei, Sajad Karampoor Journal of Digestive Diseases, 2022
Garcinia forbesii King leaf extract protects against renal tubular injury in ischemia-reperfusion injury via IL-18 and oxidative stress reduction A Rosida, N Kania, M Rudiansyah, I Oktaviyanti, R Panghiyangani, ... Tropical Journal of Pharmaceutical Research 25 (2), 205-212 , 2026 2026
Symptoms, Ways of Transmission, Prevention, and Treatment of HIV Virus: A Review AAMA El-Sehrawy, M Rudiansyah, Z Abbas, MA Gati, BA Ahmed, ... 2026
Integrating Metabolomics LC-HRMS, and Network Pharmacology of Garcinia forbesii King Leaf Extract, Potential for Treatment of Renal Ischemic Reperfusion Injury. A Rosida, N Kania, M Rudiansyah, F Fujiati, O Illiandri, WR Devi Tropical Journal of Natural Product Research 9 (10) , 2025 2025
Comparison of stingless bee honey and silver sulfadiazine on diabetic wound healing in rat models NM Fajari, A Pranoto, DS Perdanakusuma, MD Prenggono, ... Medical Journal of Indonesia 34 (3), 151-7 , 2025 2025
DAUN MUNDAR (Garcinia forbesii King) Eksplorasi Metabolomik dan Mekanisme Molekuler pada Proteksi Ginjal A Rosida, N Kania, M Rudiansyah ULM Press , 2025 2025
Prognostic Nutritional Index (PNI) at Admission Predicts In-Hospital Mortality of COVID-19-Infected Patients H Haryati, M Isa, M Rudiansyah, J Juhairina, M Nor, FR Arganita Majalah Kedokteran Bandung 57 (2), 119-127 , 2025 2025
The effect of resistant dextrin on glucose regulation markers in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials M Rudiansyah, DA Salman, H Doshi, R Jyothi S, D Shit, S Sharma, ... BMC nutrition 11 (1), 91 , 2025 2025 Citations: 3
Hubungan Indeks Massa Tubuh Dan Tekanan Darah N Nurhayati, M Rudiansyah, DIN Pratiwi, F Mutaqqien, M Bakhriansyah Homeostasis 7 (3), 561-568 , 2025 2025 Citations: 2
HUBUNGAN ANTARA GANGGUAN DEPRESI DAN KUALITAS HIDUP PADA PASIEN HEMODIALISIS DI RSUD ULIN BANJARMASIN MR Zulfikar, M Rudiansyah, DIN Pratiwi, WASN Cahyawati, D Marisa Homeostasis 7 (3), 481-488 , 2025 2025
THE RELATIONSHIP OF PRE-AND POST-OPERATIVE KIDNEY FUNCTION AND THE DEGREE OF HYDRONEPHROSIS CAUSED BY STONES AND MALIGNANCY IN PATIENTS WHO HAVE HAD A DJ STENT INSTALLED E RAHMAN, EP MAULANI, A YASMINA, H SUTAPA, IZ AKBAR, ... JBN (JURNAL BEDAH NASIONAL) Учредители: Universitas Udayana 9 (1), 8 , 2025 2025
Efek Toksik Pemberian Ekstrak Daun Mundar (Garcinia forbesii King) Pada Ginjal Rattus norvegicus Jantan Galur Wistar A Rosida, AS Reyhana, E Wydiamala, J Joharman, M Rudiansyah, ... JPSCR: Journal of Pharmaceutical Science and Clinical Research 10 (2), 176-189 , 2025 2025
Prognostic Nutritional Index (PNI) at Admission Predicts In-Hospital Mortality of COVID-19-Infected Patients M Isa, M Rudiansyah, J Juhairina, M Nor, FR Arganita Faculty Of Medicine Universitas Padjajaran , 2025 2025
Acute oral toxicity test and determination of lethal dose (LD50) of Garcinia forbesii King leaf extract in wistar rats M Rudiansyah, A Rosida, N Kania, W Riza Devi, N Nirmalasari 2025
Correlation among Blood Sugar Levels, C-Reactive Protein, Total Lymphocyte Count with SOFA Score on Sepsis COVID-19 Patients NM Fajari, I Hartono, M Rudiansyah, WA SNC, A Yasmina Clinical and Research Journal in Internal Medicine 5 (2), 134-139 , 2024 2024
Correlation Between RET-He and Quality of Life in Chronic Kidney Disease Patients with Routine Hemodialysis: A Study at Ulin General Hospital Banjarmasin A Fariz, M Rudiansyah, ER Kurniaatmaja, NT Wulandari, DIN Pratiwi Indonesian Journal of Kidney and Hypertension 1 (2), 5-11 , 2024 2024
KORELASI KADAR MASSA OTOT DAN KUALITAS HIDUP PADA PASIEN YANG MENJALANI HEMODIALISIS RUTIN DI RSUD ULIN BANJARMASIN A Ariewardana, M Rudiansyah, DIN Pratiwi, WASN Cahyawati, D Marisa Homeostasis 7 (2), 289-298 , 2024 2024
HUBUNGAN KADAR ALBUMIN DAN KEKUATAN OTOT GENGGAMAN AL Farsya, M Rudiansyah, DIN Pratiwi, F Muttaqien, M Bakhriansyah Homeostasis 7 (2), 307-314 , 2024 2024
Herbal therapy in diabetes mellitus: A review B Gholamine, J Malviya, M Rudiansyah, MK Abid, AH Alawadi, OA Adeli, ... Advancements in Life Sciences 11 (1), 40-48 , 2024 2024 Citations: 13
Recent advances in Biosensor devices for HER-2 cancer biomarker detection S Chupradit, SA Jasim, D Bokov, MZ Mahmoud, AB Roomi, K Hachem, ... Authorea Preprints , 2024 2024
Beneficial alterations in growth performance, blood biochemicals, immune responses, and antioxidant capacity of common carp (Cyprinus carpio) fed a blend of Thymus vulgaris … M Rudiansyah, WK Abdelbasset, SA Jasim, G Mohammadi, ... AQUACULTURE 578 , 2024 2024
MOST CITED SCHOLAR PUBLICATIONS
Effect of tomato consumption on inflammatory markers in health and disease status: A systematic review and meta-analysis of clinical trials G Widjaja, M Rudiansyah, MQ Sultan, MJ Ansari, SE Izzat, MS Al Jaber, ... Clinical nutrition ESPEN 50, 93-100 , 2022 2022 Citations: 70
Coronavirus disease 2019 (COVID‐19) update: From metabolic reprogramming to immunometabolism M Rudiansyah, SA Jasim, ZG Mohammad Pour, SS Athar, AS Jeda, ... Journal of medical virology 94 (10), 4611-4627 , 2022 2022 Citations: 52
Optical-based biosensor for detection of oncomarker CA 125, recent progress and current status AV Yumashev, M Rudiansyah, S Chupradit, MM Kadhim, AT Jalil, ... Analytical biochemistry 655, 114750 , 2022 2022 Citations: 46
RETRACTED: Beneficial alterations in growth performance, blood biochemicals, immune responses, and antioxidant capacity of common carp (Cyprinus carpio) fed a blend of Thymus … M Rudiansyah, WK Abdelbasset, SA Jasim, G Mohammadi, ... Aquaculture 555, 738254 , 2022 2022 Citations: 45
Role of alloying composition on mechanical properties of CuZr metallic glasses during the nanoindentation process SA Jasim, MH Ali, ZH Mahmood, M Rudiansyah, FH Alsultany, YF Mustafa, ... Metals and Materials International 28 (9), 2075-2082 , 2022 2022 Citations: 42
Recent advances in biosensor devices for HER-2 cancer biomarker detection S Chupradit, SA Jasim, D Bokov, MZ Mahmoud, AB Roomi, K Hachem, ... Analytical Methods 14 (13), 1301-1310 , 2022 2022 Citations: 33
Emerging optical and electrochemical biosensing approaches for detection of ciprofloxacin residues in food and environment samples: A comprehensive overview MJ Ansari, DO Bokov, SA Jasim, M Rudiansyah, W Suksatan, G Yasin, ... Journal of Molecular Liquids 354, 118895 , 2022 2022 Citations: 29
Alendronate reinforced polycaprolactone-gelatin-graphene oxide: A promising nanofibrous scaffolds with controlled drug release HS Budi, A Davidyants, M Rudiansyah, MJ Ansari, W Suksatan, ... Materials Today Communications 32, 104108 , 2022 2022 Citations: 28
Osteoporosis treatment by mesenchymal stromal/stem cells and their exosomes: Emphasis on signaling pathways and mechanisms M Rudiansyah, AA El-Sehrawy, I Ahmad, EM Terefe, WK Abdelbasset, ... Life sciences 306, 120717 , 2022 2022 Citations: 23
COVID-19 and kidney diseases in Indonesia M Rudiansyah 2020 Citations: 22
Java barb fish gallbladder–induced acute kidney injury and ischemic acute hepatic failure M Rudiansyah, L Lubis, R Bandiara, R Supriyadi, RS Gondodiputro, ... Kidney International Reports 5 (5), 751-753 , 2020 2020 Citations: 21
The emerging microbiome‐based approaches to IBD therapy: from SCFAs to urolithin A M Rudiansyah, S Abdalkareem Jasim, B S. Azizov, V Samusenkov, ... Journal of digestive diseases 23 (8-9), 412-434 , 2022 2022 Citations: 20
Hubungan Antara Adekuasi Hemodialisis Dan Kualitas Hidup Pasien Di RSUD Ulin Banjarmasin: Tinjauan Terhadap Pasien Penyakit Ginjal Kronik Yang Menjalani Hemodialisis Rutin ARA Rahman, M Rudiansyah, T Triawanti Berkala Kedokteran 9 (2), 151-160 , 2013 2013 Citations: 20
Treatment of pilocarpine-induced epileptic seizures in adult male mice WK Abdelbasset, SA Jasim, M Rudiansyah, H Huldani, R Margiana, ... Brazilian Journal of Biology 84, e260091 , 2022 2022 Citations: 16
The Correlation between Fibroblast Growth Factor 23 (FGF23) and Iron Profile in Chronic Kidney Disease Patients on Dialysis with Anemia. M Rudiansyah, L Lubis, R Bandiara, BM Sanjaya, HW Nur'amin, ... Systematic Reviews in Pharmacy 11 (6) , 2020 2020 Citations: 14
Herbal therapy in diabetes mellitus: A review B Gholamine, J Malviya, M Rudiansyah, MK Abid, AH Alawadi, OA Adeli, ... Advancements in Life Sciences 11 (1), 40-48 , 2024 2024 Citations: 13
Investigation of parameters in restaurant food waste for use as poultry rations Y Garnida, M Rudiansyah, G Yasin, T Mahmudiono, AJ Kadhim, ... Food Science and Technology 42, e118621 , 2022 2022 Citations: 13
Potential of chimeric antigen receptor (CAR)‐redirected immune cells in breast cancer therapies: Recent advances M Nikoo, M Rudiansyah, DO Bokov, NT Jainakbaev, W Suksatan, ... Journal of cellular and molecular medicine 26 (15), 4137-4156 , 2022 2022 Citations: 12
Socioeconomic Determinants of Tuberculosis Cases in Indonesia, 2010–2013: An Ecological Study TA Wanahari, M Bakhriansyah, H Haryati, M Rudiansyah, M Isa, ... Open Access Macedonian Journal of Medical Sciences 10 (E), 1489-1495 , 2022 2022 Citations: 12
The role of selenium on the status of mineral elements and some blood parameters of blood serum of lambs M Rudiansyah, MM Kadhim, A Tolmasovich Shamsiev, AS Prakaash, ... Archives of Razi Institute 78 (1), 135 , 2023 2023 Citations: 11