Mª Carmen Martín Gómez

@saludcastillayleon.es

Complejo Asistencial Universitario de Salamanca - Servicio de Psiquiatría
Psiquiatra

Mª Carmen Martín Gómez


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15

Scopus Publications

Scopus Publications

  • Impact on Sleep Quality, Mood, Anxiety, and Personal Satisfaction of Doctors Assigned to COVID-19 Units
    Pilar Andrés-Olivera, Judit García-Aparicio, María Teresa Lozano López, José Antonio Benito Sánchez, Carmen Martín, Ana Maciá-Casas, Armando González-Sánchez, Miguel Marcos, Carlos Roncero
    International Journal of Environmental Research and Public Health, 2022
    The SARS-CoV-2 health emergency has led to a restructuring of health care systems and the reassignment of medical specialists from their usual duties to attend COVID-19 patients. The aim of this paper is to describe the levels of insomnia, anxiety, depression, and the impact on quality of life of doctors who were on the frontline of COVID-19 during the first two waves of the pandemic. Self-report surveys were conducted on said physicians during both waves, with 83 and 61 responses in the first and second waves, respectively. The reported presence of insomnia was frequent (71.8%), although it decreased in the second survey. Anxiety was moderate, decreasing from 57.1% to 43.1% between measurements. Overall, depression rates decreased between the two surveys. Substance use was found to have an indirect correlation with personal and professional satisfaction. In the light of the unforeseeable evolution of the pandemic and the medium- to long-term repercussions on professionals, we believe the adaptation of health resources is crucial to meet the new unpredictable mental health needs of this group.
  • COVID pandemic as an opportunity for improving mental health treatments of the homeless people
    Carmen Martin, Pilar Andrés, Alberto Bullón, José Luis Villegas, Javier Ignacio de la Iglesia-Larrad, Berta Bote, Nieves Prieto, Carlos Roncero
    International Journal of Social Psychiatry, 2021
    Background: Homeless population has been severely affected by the COVID-19 pandemic. Their living conditions, comorbidity with different pathologies and a greater frequency of mental disorders, make this population vulnerable. Method: We implemented a program of serial visits in a hostel for confined homeless of the city council social services, for the monitoring and treatment of mental disorders and substance abuse problems. Accompanied by serial phone and email contacts. Results: A highly significant percentage (63%) had mental disorders or substance abuse, requiring pharmacological intervention, and 37% began follow-up in resources of the Mental Health and Addiction network of the Psychiatric Service at the end of the program. Hospital emergency service visits were drastically reduced. None of them were infected with COVID-19. An individualized Social plan was drawn up in order to reintegrate them with support in the community. Conclusions: The Results have been really positive, meeting all the objectives and opening up developing new programs in the future, in the pandemic outbreak and out of it.
  • The response of the mental health network of the Salamanca area to the COVID-19 pandemic: The role of the telemedicine.
    Carlos Roncero, Llanyra García-Ullán, Javier I. de la Iglesia-Larrad, Carmen Martín, Pilar Andrés, Ana Ojeda, David González-Parra, Javier Pérez, Clara Fombellida, Ana Álvarez-Navares, José Antonio Benito, Virginia Dutil, Carolina Lorenzo, Ángel Luis Montejo
    Psychiatry Research, 2020
    The COVID-19 pandemic reached world-wide causing a great impact on healthcare services. The aim of this work is to describe the response of the Mental Health Network of the Salamanca´ Area (Spain) to this crisis and the reorganization of its resources within the first 8 weeks after the state of alarm was declared. The Psychiatry Service applied a contingency plan which included the reorganization of the human resources, the closure of some of the units and the implementation of telemedicine programs along with two specific programs, namely a mental health assistance program in the context of the infection by coronavirus, and another program for homeless people. 9.038 phone interviews were carried out in the outpatients and community mental health programs. The activity in subacute and acute wards, as well as that of the day hospital programs was decreased to 50%. Based on that this real-world response provided we concluded that the usage of telemedicine is promising in patients with any kind of disorder. Its implementation in daily practice will be considered in the future. Research must continue on COVID-19′s impact on patients with mental disorders and Psychiatry's necessary adaptations and new approaches to them.
  • Abnormal self-experiences related to a hypersynchronic brain state in schizophrenia
    Marta Hernández-García, Carmen Martín-Gómez, Marta Gómez-García, Javier Gomez-Pilar, Pablo Núñez-Novo, Antonio Arjona-Valladares, María Victoria Alejos-Herrera, Maria Teresa Lozano-López, Sinta Gamonal Limcaoco, Carlos Molina-Novoa, Vicente Molina
    Schizophrenia Research, 2020
  • Psychotic symptoms following oxycodone withdrawal, case report and update
    N. Casado-Espada, C. Martin, J. I. de la Iglesia-Larrad, R. de Alarcón, C. Fombellida, L. Fernández-Martín, C. Roncero
    European Review for Medical and Pharmacological Sciences, 2019
    Opiate withdrawal-induced psychosis is an uncommon clinical manifestation. We present a 36-year-old male patient, with no prior personal or familiar psychiatric history, in treatment with several analgesic drugs (including oxycodone) for non-inflammatory chronic rachialgia. The patient is hospitalized after exhibiting psychotic symptomatology (delusions of harm and contamination, olfactory hallucinations, and aberrant behavior). This psychotic symptomatology first manifested after abruptly interrupting his prescribed oxycodone intake. It had a fluctuating course over time (alternating between lucid states and delusional ones) and eventually subsided after the prescription of antipsychotic drugs. In this case report, we describe the follow-up of the patient and discuss the influence and relevance of oxycodone withdrawal on the psychotic symptomatology.
  • Elevated noise power in gamma band related to negative symptoms and memory deficit in schizophrenia
    Vanessa Suazo, Álvaro Díez, Carmen Martín, Alejandro Ballesteros, Pilar Casado, Manuel Martín-Loeches, Vicente Molina
    Progress in Neuro Psychopharmacology and Biological Psychiatry, 2012
    BACKGROUND There is an increasing consideration for a disorganized cerebral activity in schizophrenia, perhaps relating to a synaptic inhibitory deficit in the illness. Noise power (scalp-recorded electroencephalographic activity unlocked to stimuli) may offer a non-invasive window to assess this possibility. METHODS 29 minimally-treated patients with schizophrenia (of which 17 were first episodes) and 27 healthy controls underwent clinical and cognitive assessments and an electroencephalographic recording during a P300 paradigm to calculate signal-to-noise ratio and noise power magnitudes in the theta and gamma bands. RESULTS In comparison to controls, a significantly higher gamma noise power was common to minimally-treated and first episode patients over P3, P4, T5 and Fz electrode sites. Those high values were directly correlated to negative symptom severity and inversely correlated to verbal memory scores in the patients. There were no differences in signal-to-noise ratio magnitudes among the groups. Gamma noise power at Fz discriminated significantly between patients and controls. No significant differences were found in theta noise power or in gamma noise power over the other electrode sites between the groups of patients and controls. LIMITATIONS We have not assessed phase-locked and non-phase locked power changes, a complementary approach that may yield useful information. CONCLUSIONS Gamma noise power may represent a useful and non-invasive tool for studying brain dysfunction in psychotic illness. These results suggest an inefficient activation pattern in schizophrenia.
  • Optimized voxel brain morphometry: Association between brain volumes and the response to atypical antipsychotics
    Vicente Molina, Carmen Martín, Alejandro Ballesteros, Alba G. Seco de Herrera, Juan Antonio Hernández-Tamames
    European Archives of Psychiatry and Clinical Neuroscience, 2011
    To date, few studies have addressed the relationship between brain structure alterations and responses to atypical antipsychotics in schizophrenia. To this end, in this study, magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) were used to assess the relationship between the brain volumes of gray (GM) and white (WM) matters and the clinical response to risperidone or olanzapine in 30 schizophrenia patients. In comparison with healthy controls, the patients in this study showed a bilateral decrease in the anteromedial cerebellar hemispheres, the rectal gyrus and the insula, together with bilateral increases in GM in the basal ganglia. Both patient groups had a significantly smaller volume of WM in a region encompassing the internal and external capsules as compared to the controls. We found an inverse association between striatal size and the degree of clinical improvement, and a direct association between the degree of insular volume deficit and its improvement. The non-responder patient group showed a significant decrease in their left rectal gyrus as compared with the responder group. This study reveals a pattern of structural alterations in schizophrenia associated with the response to risperidone or olanzapine.
  • Prepulse inhibition of the startle reflex in schizophrenia remains stable with short-term quetiapine
    V. Molina, D.E. López, R. Villa, J. Pérez, C. Martín, A. Ballesteros, A. Cardoso, C. Sancho
    European Psychiatry, 2011
    PurposeTo study the short-term effect of treatment with quetiapine on prepulse inhibition (PPI) deficits of the startle reflex in schizophrenia patients.Subjects and methodsUsing PPI, we studied a group of 21 schizophrenia patients and 16 controls. Seventeen of the patients were re-tested with PPI after 21 days of treatment with quetiapine.ResultsAt baseline, an almost significant decrease in PPI was found in the patients as compared to the controls. PPI measurements did not change in the patients after 21 days of treatment with quetiapine, despite their clinical improvement.ConclusionOur results suggest that short-term quetiapine treatment may not modify PPI measures in schizophrenia patients.
  • No association between prepulse inhibition of the startle reflex and neuropsychological deficit in chronic schizophrenia
    Vicente Molina, Benjamín Cortés, Javier Pérez, Carmen Martín, Rocío Villa, Dolores E. López, Consuelo Sancho
    European Archives of Psychiatry and Clinical Neuroscience, 2010
    Sensorimotor gating deficits are relevant in schizophrenia and can be measured using prepulse inhibition (PPI) of the startle reflex. It is conceivable that such deficits may hinder the cognitive functions in schizophrenia patients. In this study, using PPI and a neuropsychological battery, we studied this possibility in a group of 23 acute, neuroleptic-free schizophrenia patients and 16 controls. A non-significant decrease in PPI was found in the patients as compared to the controls, as well as significant differences in the performance of Trail A and B in Wisconsin Card Sorting and Digit/Symbol Tests. No statistically significant correlations between PPI and neuropsychological performance were found after the correction for multiple comparisons in any group. Our results suggest that PPI deficits in schizophrenia patients may not contribute to the cognitive deficits typical of that illness, at least in patients with a non-significant PPI decrease.
  • Subcortical and cortical gray matter differences between Kraepelinian and non-Kraepelinian schizophrenia patients identified using voxel-based morphometry
    Vicente Molina, Juan A. Hernández, Javier Sanz, Juan C. Paniagua, Ana I. Hernández, Carmen Martín, Juan Matías, Julia Calama, Berta Bote
    Psychiatry Research Neuroimaging, 2010
    The long-term outcome of schizophrenia patients may differ depending on their brain structure. This would be reflected in significant structural differences between poor-outcome (i.e., Kraepelinian) and non-Kraepelinian patients. To assess this possibility, we have evaluated the degree of deviation in brain structure in Kraepelinian patients with respect to controls and non-Kraepelinian schizophrenia patients. We used voxel-brain morphometry (VBM) to assess the differences in gray matter volume across the brain in the Kraepelinian group with respect to the healthy controls and non-Kraepelinian patients. Twenty-six Kraepelinian and 18 non-Kraepelinian schizophrenia patients and 41 healthy controls were included. With respect to the healthy controls, the Kraepelinian patients showed a very significant decrease in gray matter in the frontal, occipital, and limbic cortices, and, at a subcortical level, bilaterally in the striatum and thalamus. In comparison with the non-Kraepelinian patients, the Kraepelinian individuals continued to show a similar subcortical decrease. Thus, Kraepelinian patients may be characterized by a distinct pattern of brain abnormalities, in particular, in subcortical regions.
  • Clozapine may partially compensate for task-related brain perfusion abnormalities in risperidone-resistant schizophrenia patients
    V. Molina, P. Tamayo, C. Montes, A. De Luxán, C. Martin, N. Rivas, C. Sancho, A. Domínguez-Gil
    Progress in Neuro Psychopharmacology and Biological Psychiatry, 2008
  • A 68-year-old woman with chronic depression resistant to ambulatory treatment
    P. Franco Romo, M.C. Martn Gmez, S. Snchez Iglesias
    Medicine, 2007
  • Therapeutic protocol of chronic depression
    M.C. Martn Gmez, D. Gonzlez Parra, P. Franco Romo, S. Snchez Iglesias
    Medicine, 2007
  • Pharmacological treatment of depression
    D. Gonzlez Parra, M.C. Martn Gmez, P. Franco Romo, S. Snchez Iglesias
    Medicine, 2007
  • Diagnostic and therapeutic protocol of the behavioral changes in the elderly
    V. Gonzlez de Mara, C. Leal Snchez, M.C. Martn Gmez, S. Snchez Iglesias
    Medicine, 2007