Impact of Tranexamic Acid on Bleeding Outcomes and Complication Rates in Facelift: A Systematic Review and Meta-analysis Abdulaziz Saud Alenazi, Amani A Obeid, Abdulaziz Alderaywsh, Abdulaziz Alrabiah, Osama Alkaoud, Mona Ashoor, Badi Aldosari, Ahmed M Alarfaj Aesthetic Surgery Journal, 2024 Background Rhytidectomy poses a significant risk of bleeding. Several studies have reported the safety profile and efficacy of tranexamic acid (TXA), an antifibrinolytic agent, in minimizing perioperative sequelae, particularly hematoma and bleeding. Objectives The aim of this systematic review was to analyze the effect of TXA administration in facelift surgery, its effect with different routes of administration, and to compare different administration routes in reducing intraoperative blood loss, postoperative edema, and ecchymosis in rhytidectomy. Methods A systematic literature search was conducted to identify studies that reported on TXA in facelift surgery. The primary outcomes of interest were intraoperative blood loss, time to achieve hemostasis, operation duration, and postoperative hematoma, edema, ecchymosis, drain output, and major and minor complications. Meta-analyses of hematoma, operation duration, drain output, and major and minor complications were performed, and the risk of bias was assessed with ROBINS-I for nonrandomized studies, and Cochrane's RoB 2.0, a tool for randomized controlled trials. Results In total, 104 articles were included in the initial screening. Out of 388 participants 170 patients were administered TXA, predominantly female (over 91%), with ages from the late 50s to mid-60s. TXA administration varied, with subcutaneous injection being the most common method. The meta-analysis revealed that the pooled prevalence of minor and major hematoma in TXA recipients was remarkably low, with a significant reduction in the risk of minor hematoma (odds ratio [OR] = 0.18, 95% CI 0.05-0.62, P < .001) and no significant difference in major hematoma risk. Interestingly, TXA significantly reduced postoperative drainage compared to the controls (mean difference = −25.59, 95% CI, −30.4-−20.77, P < .01). Additionally, neither minor nor major complications were significantly different between the TXA recipients and controls. Specifically, the pooled odds for the incidence of major complications were not significantly different (OR = 1.47, 95% CI, 0.23-9.19, P = .68), and similar results were found for minor complications (OR = 0.59, 95% CI, 0.23-1.48, P = .26). Conclusions TXA significantly reduces postoperative drain output and minor hematomas in facelift surgery without increasing major complications. It also reduces edema, ecchymosis, and intraoperative blood loss. However, further studies are required to explore the efficacy of TXA with different dosages and administration routes. Level of Evidence: 3
Diagnostic accuracy of intrathecal fluorescein versus other radiological modalities in evaluating non-congenital skull base defects: a systematic review and meta-analysis Salma S. AlSharhan, Hussain J. Aljubran, Danah F. Alrusayyis, Aishah A. AlGhuneem, Wasan F. AlMarzouq, Mohammed H. Al Bar, Abdulmalik S. AlSaied, Mona M. Ashoor, Abdulaziz S. ALEnazi, Amal A. Alghamdi European Archives of Oto Rhino Laryngology, 2024 Purpose The intraoperative detection of cerebrospinal fluid (CSF) leaks during endoscopic skull base surgery is critical to ensure watertight sealed defects. Intrathecal fluorescein (ITF) is a valuable adjunct to intraoperative investigation. Hence, our aim is to summarize the evidence of the efficacy of ITF as an accurate diagnostic modality and reconstruction guide for non-congenital skull base defects. Methods Using the Cochrane Central, MEDLINE, and Embase databases, we identified studies involving the use of ITF in non-congenital CSF leaks which were published until November 2023. The STATA 18 software was used for meta-analysis. Results Fourteen studies met the inclusion criteria, in which seven studies were included in the meta-analysis. ITF was used in 1898 (90.3%) of patients, with a detection rate of 88.1%. The overall detection rate of non-congenital CSF leaks among ITF concentrations of 5% and 10% had a statistically significant pooled effect size of 2.6 (95% CI = 2.25, 2.95), while when comparing the ITF to other alternative radiological tests, it was not statistically significant with a mean difference of 0.88 (95% CI = − 0.4, 2.16). Moreover, the pooled prevalence was statistically significant in regards of the complications associated with ITF with an effect size of 0.6 (95% CI = 0.39, 0.82), indicating that 60% of patients who underwent ITF would experience at least one of the measured complications. Conclusion ITF is considered as an efficient tool in localizing skull base defects. However, there was no significant results when comparing the ITF to other alternative radiological tests. Accordingly, if the ITF intervention is indicated, patients should be carefully selected based on their clinical need.
Endoscopic appearance of duplicated middle turbinate, case series and literature review Abdulaziz Saud AlEnazi, Shahad Ali Alzahrani, Adnan Al-Samarah, Mona MohammedSaleh Ashoor International Journal of Surgery Case Reports, 2023 A double middle turbinate has important clinical implications. Anatomical variation may lead to narrowing in the middle meatus which makes the patient vulnerable to sinusitis or maybe associated with secondary symptoms. We report rare cases of middle turbinate duplication. Awareness of the nasal turbinates' variations is important for detection and management of inflammatory sinus diseases. Further studies are needed to identify the association of other pathology.
Clinical otorhinolaryngological presentation of COVID-19 patients in Saudi Arabia Laila M. Telmesani, Danah H. Althomaly, Lamia A. Buohliqah, Roa T. Halawani, Mona M. Ashoor, Marwan J. Alwazzeh, Suad A. Al Mubarak, Maha A. AlHarbi, Rana F. AlMuslem, Sahal S. Arabi, Waleed E. Saleh, Amal Y. ALYosif, Mohammad R. Al Eid, Lena S. Telmesani, Abdulaziz S. AlEnazi Saudi Medical Journal, 2022 OBJECTIVES To assess the otorhinolaryngological (ORL) symptoms, including their prevalence, severity, and early presentations among coronavirus disease-19 (COVID-19) patients in the Saudi population. METHODS This was a multicentric, cross-sectional study carried out on severe acute respiratory syndrome coronavirus-2 positive patients at 3 COVID-19 centres; Imam Abdulrahman Bin Faisal University, King Fahd Hospital of the University, ALKhobar, Qatif Central Hospital, AlQatif, and Ohud Hospital, Al Madinah Al Munawarah, Saudi Arabia. The validated survey consisted of sociodemographic data, general symptoms of COVID-19, and ORL manifestations. RESULTS A total of 1734 COVID-19 positive patients were included in the study (mean age: 37.7±11.6 years). Most of the cases were mild (51.8%), followed by moderate (45.6%), and severe (2.6%) cases. Approximately 33.7% were asymptomatic. Severity of symptoms was significantly associated with male gender (p=0.017), higher age-group (p=0.04), and smoking (p<0.001). The most common initial ORL presentations were sore throat (20.9%), anosmia (15.5%), hyposmia (10%), and loss of taste (11.4%). Overall, 79.5% showed ORL symptoms as the initial presenting symptoms for COVID-19, with anosmia and sore throat being the most common symptoms. CONCLUSION This study confirmed the prevalence of ORL symptoms among COVID-19 patients in Saudi Arabia. Moreover, these symptoms could also be considered for early detection of COVID-19 as they might appear prior to other symptoms.
Long-Term Follow-Up Strategy Islam R. Herzallah, Mona Ashoor CSF Rhinorrhea Pathophysiology Diagnosis and Skull Base Reconstruction, 2022
Knowledge and practice of Protective Personal Equipment (PPE) among healthcare providers in Saudi Arabia during the early stages of COVID-19 pandemic in 2020 Mona Ashoor, Saad Alshammari, Fahad Alzahrani, Noorah Almulhem, Zaid Almubarak, et al. Journal of Preventive Medicine and Hygiene, 2021 Introduction: Healthcare providers are at high risk of becoming infected when taking care of patients who have COVID-19, especially while attending aerosol generating procedures. Protective personal equipment must be used in the correct manner to prevent transmission of the disease. Published protocols on protective personal equipment (PPE) donning and doffing have been issued by disease control agencies. Methods: A questionnaire-based cross-sectional study was designed. An online anonymous questionnaire, which was validated and tested for reliability, focused on PPE related knowledge, donning and doffing practices of healthcare providers across the eastern region of Saudi Arabia. Results: A total of 312 healthcare providers across the eastern region of Saudi Arabia participated in the study, 208 physicians (66.7%) and 104 non-physicians (33.3%). Results indicate poor practice regarding PPE donning (13.8% reported the correct sequence) and PPE doffing (3.5% reported the correct sequence) among participants. In addition, practice and confidence scores regarding other issues with PPE were analyzed. Based on questionnaire responses, being male (T = 2.825; p = 0.008), being a non-physician (T = -2.120; p = 0.014) and being an allied medical professional (F = 5.379; p = 0.003) were significantly associated with higher confidence levels. Also, being a consultant was significantly associated with higher practice scores (F = 4.774; p = 0.008). Conclusion: The study demonstrates deficiencies among healthcare providers in following the recommended practices for correctly using PPE during the pandemic. Poor practice in PPE donning and doffing necessitates additional educational and training programs focused on infection control practices.
The psychological impact of the COVID-19 pandemic on otolaryngologists: Should we be concerned? Mona Mohammedsaleh Ashoor, Noorah Jamal Almulhem, Zaid Abdulrahman AlMubarak, Ahmed Abdulrahman Alrahim, Saad Mohammed Alshammari, Fahad Saleh Alzahrani, Ali Radi Alhayek, Abdullah Alardhi Laryngoscope Investigative Otolaryngology, 2021 Physicians on the frontline of the COVID‐19 pandemic are at increased risk of contracting the disease. Otolaryngologists are amongst the high‐risk practitioners, as they are in close proximity to patient's upper airway, which may induce their psychological stress.
Radiological sinonasal anatomy: Exploring the Saudi population Redha A. Alrumaih, Mona M. Ashoor, Ahmed A. Obidan, Khulood M. Al-Khater, Saeed A. Al-Jubran Saudi Medical Journal, 2016 Objectives: To assess the prevalence of common radiological variants of sinonasal anatomy among Saudi population and compare it with the reported prevalence of these variants in other ethnic and population groups. Methods: This is a retrospective cross-sectional study of 121 computerized tomography scans of the nose and paranasal sinuses of patients presented with sinonasal symptoms to the Department of Otorhinolarngology, King Fahad Hospital of the University, Khobar, Saudi Arabia, between January 2014 and May 2014. Results: Scans of 121 patients fulfilled inclusion criteria were reviewed. Concha bullosa was found in 55.4%, Haller cell in 39.7%, and Onodi cell in 28.9%. Dehiscence of the internal carotid artery was found in 1.65%. Type-1 and type-2 optic nerve were the prevalent types. Type-II Keros classification of the depth of olfactory fossa was the most common among the sample (52.9%). Frontal cells were found in 79.3%; type I was the most common. Conclusions: There is a difference in the prevalence of some radiological variants of the sinonasal anatomy between Saudi population and other study groups. Surgeon must pay special attention in the preoperative assessment of patients with sinonasal pathology to avoid undesirable complications.
Nasal chondromesenchymal hamartoma in an adolescent with pleuropulmonary blastoma Saudi Medical Journal, 2014
Orbital complications in allergic fungal rhinosinusitis: a case series from a tertiary center hospital experience MR Alabdulaal, HJ Aljubran, MA Alfaleh, SH Eksail, MM Ashoor, ... AME Case Report 10, 79 , 2026 2026
Impact of tranexamic acid on bleeding outcomes and complication rates in facelift: a systematic review and meta-analysis AS Alenazi, AA Obeid, A Alderaywsh, A Alrabiah, O Alkaoud, M Ashoor, ... Aesthetic Surgery Journal 44 (11), NP749-NP761 , 2024 2024 Citations: 9
Diagnostic accuracy of intrathecal fluorescein versus other radiological modalities in evaluating non-congenital skull base defects: a systematic review and meta-analysis SS AlSharhan, HJ Aljubran, DF Alrusayyis, AA AlGhuneem, ... European Archives of Oto-Rhino-Laryngology 281 (9), 4435-4454 , 2024 2024 Citations: 2
COMPARATIVE IMAGING MODALITIES FOR DIAGNOSING ROTATOR CUFF INJURIES AF ABORUKBAH, MM ASHOOR, HA ELBASHIR, ST NAMRI, EA HAMDI, ... INTERNATIONAL JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH 11 (11), 4512-4517 , 2024 2024
Orthopedic sports injuries: Advanced imaging modalities, return-to-play criteria, and injury prevention AF Aborukbah, HA Elbashir, MR Alajmi, YK Shagdar, NA Albadrani, ... 2024 Citations: 3
Anatomical variations of sphenoid sinus among the population of the Eastern province of Saudi Arabia B Alkhudair, M Ashoor, N Almulhim, D Alkhudair Journal of ENT and Healthcare 3 (1) , 2024 2024 Citations: 1
Clinical Practice Trends in Otolaryngology for the Prevention of Ear Ventilation Tube Blockage AS Alenazi, AA Alzhrani, WM Alshehri, AH Alherz, MMS Ashoor Saudi Journal of Otorhinolaryngology Head and Neck Surgery 26 (1), 1-5 , 2024 2024
Endoscopic appearance of duplicated middle turbinate, case series and literature review AS AlEnazi, SA Alzahrani, A Al-Samarah, MMS Ashoor International journal of surgery case reports 104, 107919 , 2023 2023 Citations: 2
Retropharyngeal emphysema following local palate trauma AS AlEnazi, ZJA AlMuhanna, AS Alfaraj, HAA AlKhawaja, SK AlTamimi, ... Cureus 14 (11) , 2022 2022 Citations: 3
Long-Term Follow-Up Strategy IR Herzallah, M Ashoor CSF Rhinorrhea: Pathophysiology, Diagnosis and Skull Base Reconstruction … , 2022 2022
Clinical otorhinolaryngological presentation of COVID-19 patients in Saudi Arabia: a multicenter study LM Telmesani, DH Althomaly, LA Buohliqah, RT Halawani, MM Ashoor, ... Saudi Medical Journal 43 (3), 266 , 2022 2022 Citations: 8
Knowledge and practice of Protective Personal Equipment (PPE) among healthcare providers in Saudi Arabia during the early stages of COVID-19 pandemic in 2020 M Ashoor, S Alshammari, F Alzahrani, N Almulhem, Z Almubarak, ... Journal of Preventive Medicine and Hygiene 62 (4), E830 , 2022 2022 Citations: 14
The psychological impact of the COVID‐19 pandemic on otolaryngologists: Should we be concerned? MM Ashoor, NJ Almulhem, ZA AlMubarak, AA Alrahim, SM Alshammari, ... Laryngoscope Investigative Otolaryngology 6 (3), 576-585 , 2021 2021 Citations: 15
Knowledge and practice of protective personal equipment (PPE) among health care providers in Saudi Arabia during the early stages of COVID-19 Pandemic in 2020 journal of preventive medicine and hygiene 62 (4) , 2021 2021
Nasal bone measurements in the middle eastern population based on radiological analysis: A cross-sectional retrospective study SS Al Sharhan, MI Al Somali, FS Al Zahrani, MM Ashoor, SF Almarzouq, ... Saudi Journal of Otorhinolaryngology Head and Neck Surgery 22 (2), 57-62 , 2020 2020 Citations: 3
A rare presentation of inflammatory myofibroblastic tumor in the nasolabial fold HK Alshammari, HF Alzamami, M Ashoor, WF Almarzouq, H Kussaibi Case Reports in Otolaryngology 2019 (1), 3257697 , 2019 2019 Citations: 12
Psammomatoid ossifying fibroma of the ethmoid sinus with secondary intracranial Aneurymal bone cyst: a case report and literature review SS Al-Sharhan, MM Ashoor, AM Al-Nemer Saudi Journal of Medicine & Medical Sciences 4 (2), 125-128 , 2016 2016 Citations: 4
Radiological sinonasal anatomy: exploring the saudi population RA Alrumaih, MM Ashoor, AA Obidan, KM Al-Khater, SA Al-Jubran Saudi Medical Journal 37 (5), 521 , 2016 2016 Citations: 41
Prevalence and analysis of concha bullosa among patients undergoing functional reconstructive nasal surgeries K Al-Dilaijan, M Ashoor, Y Al-Dilaijan, A Khamis Saudi Journal of Otorhinolaryngology Head and Neck Surgery 17 (1), 26-31 , 2015 2015 Citations: 1
Maxillary sinus hematoma: current pathogenesis and management M Almasoud, A Alhumaidan, M Ashoor Egyptian Journal of Ear, Nose, Throat and Allied Sciences 15 (1), 37-40 , 2014 2014 Citations: 6
MOST CITED SCHOLAR PUBLICATIONS
Radiological sinonasal anatomy: exploring the saudi population RA Alrumaih, MM Ashoor, AA Obidan, KM Al-Khater, SA Al-Jubran Saudi Medical Journal 37 (5), 521 , 2016 2016 Citations: 41
The psychological impact of the COVID‐19 pandemic on otolaryngologists: Should we be concerned? MM Ashoor, NJ Almulhem, ZA AlMubarak, AA Alrahim, SM Alshammari, ... Laryngoscope Investigative Otolaryngology 6 (3), 576-585 , 2021 2021 Citations: 15
Knowledge and practice of Protective Personal Equipment (PPE) among healthcare providers in Saudi Arabia during the early stages of COVID-19 pandemic in 2020 M Ashoor, S Alshammari, F Alzahrani, N Almulhem, Z Almubarak, ... Journal of Preventive Medicine and Hygiene 62 (4), E830 , 2022 2022 Citations: 14
A rare presentation of inflammatory myofibroblastic tumor in the nasolabial fold HK Alshammari, HF Alzamami, M Ashoor, WF Almarzouq, H Kussaibi Case Reports in Otolaryngology 2019 (1), 3257697 , 2019 2019 Citations: 12
Nasal chondromesenchymal hamartoma in an adolescent with pleuropulmonary blastoma AA Obidan, MM Ashoor Saudi Medical Journal 35 (8), 876-878 , 2014 2014 Citations: 11
Impact of tranexamic acid on bleeding outcomes and complication rates in facelift: a systematic review and meta-analysis AS Alenazi, AA Obeid, A Alderaywsh, A Alrabiah, O Alkaoud, M Ashoor, ... Aesthetic Surgery Journal 44 (11), NP749-NP761 , 2024 2024 Citations: 9
Clinical otorhinolaryngological presentation of COVID-19 patients in Saudi Arabia: a multicenter study LM Telmesani, DH Althomaly, LA Buohliqah, RT Halawani, MM Ashoor, ... Saudi Medical Journal 43 (3), 266 , 2022 2022 Citations: 8
Long term results of transseptal suture of the middle turbinate during sinus surgery G Rettinger, K Lindemann, M Ashoor, M Scheithauer, F Sommer, ... Laryngo-Rhino-Otologie 90 (8), 471-475 , 2011 2011 Citations: 8
Maxillary sinus hematoma: current pathogenesis and management M Almasoud, A Alhumaidan, M Ashoor Egyptian Journal of Ear, Nose, Throat and Allied Sciences 15 (1), 37-40 , 2014 2014 Citations: 6
Langzeitergebnisse der transseptalen Naht der mittleren Nasenmuscheln bei Siebbeinoperationen G Rettinger, K Lindemann, M Ashoor, M Scheithauer, F Sommer, ... Laryngo-Rhino-Otologie 90 (08), 471-475 , 2011 2011 Citations: 5
Psammomatoid ossifying fibroma of the ethmoid sinus with secondary intracranial Aneurymal bone cyst: a case report and literature review SS Al-Sharhan, MM Ashoor, AM Al-Nemer Saudi Journal of Medicine & Medical Sciences 4 (2), 125-128 , 2016 2016 Citations: 4
Orthopedic sports injuries: Advanced imaging modalities, return-to-play criteria, and injury prevention AF Aborukbah, HA Elbashir, MR Alajmi, YK Shagdar, NA Albadrani, ... 2024 Citations: 3
Retropharyngeal emphysema following local palate trauma AS AlEnazi, ZJA AlMuhanna, AS Alfaraj, HAA AlKhawaja, SK AlTamimi, ... Cureus 14 (11) , 2022 2022 Citations: 3
Nasal bone measurements in the middle eastern population based on radiological analysis: A cross-sectional retrospective study SS Al Sharhan, MI Al Somali, FS Al Zahrani, MM Ashoor, SF Almarzouq, ... Saudi Journal of Otorhinolaryngology Head and Neck Surgery 22 (2), 57-62 , 2020 2020 Citations: 3
Diagnostic accuracy of intrathecal fluorescein versus other radiological modalities in evaluating non-congenital skull base defects: a systematic review and meta-analysis SS AlSharhan, HJ Aljubran, DF Alrusayyis, AA AlGhuneem, ... European Archives of Oto-Rhino-Laryngology 281 (9), 4435-4454 , 2024 2024 Citations: 2
Endoscopic appearance of duplicated middle turbinate, case series and literature review AS AlEnazi, SA Alzahrani, A Al-Samarah, MMS Ashoor International journal of surgery case reports 104, 107919 , 2023 2023 Citations: 2
Anatomical variations of sphenoid sinus among the population of the Eastern province of Saudi Arabia B Alkhudair, M Ashoor, N Almulhim, D Alkhudair Journal of ENT and Healthcare 3 (1) , 2024 2024 Citations: 1
Prevalence and analysis of concha bullosa among patients undergoing functional reconstructive nasal surgeries K Al-Dilaijan, M Ashoor, Y Al-Dilaijan, A Khamis Saudi Journal of Otorhinolaryngology Head and Neck Surgery 17 (1), 26-31 , 2015 2015 Citations: 1
Orbital complications in allergic fungal rhinosinusitis: a case series from a tertiary center hospital experience MR Alabdulaal, HJ Aljubran, MA Alfaleh, SH Eksail, MM Ashoor, ... AME Case Report 10, 79 , 2026 2026
COMPARATIVE IMAGING MODALITIES FOR DIAGNOSING ROTATOR CUFF INJURIES AF ABORUKBAH, MM ASHOOR, HA ELBASHIR, ST NAMRI, EA HAMDI, ... INTERNATIONAL JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH 11 (11), 4512-4517 , 2024 2024