Angela Ogechukwu Ugwu

@unn.edu.ng

Associate Professor/Consultant Haematologist/ Haematology & Immunology Department/Faculty of Medical Sciences
College of Medicine, University of Nigeria Ituku/Ozalla

Angela Ogechukwu Ugwu


                        Download Compact PDF  
https://researchid.co/angelao.ugwu
Dr. Angela Ogechukwu Ugwu is a native of Ibagwa-Ani in Nsukka LGA of Enugu State. She obtained her MBBS degree from Nnamdi Azikiwe University, Awka in 2006 and later FMCPath in 2014 from the National Postgraduate Medical College of Nigeria. She also obtained her Doctor of medicine (MD) in 2023 from same College.
Dr. Angela Ugwu has initiated and completed several research works in areas of sickle cell anaemia, transfusion medicine, hemato-oncology, coagulation disorders and Cochrane systematic reviews. Consequently, she has published 54 papers in peer review journals (locally and internationally), with 31 of these papers published in journals with Thompson Reuters and SCimago Impact Factors/Ratings. She was the Principal investigator in one of the grants she attracted to the College.

EDUCATION

MBBS
MD
FMCPath

RESEARCH INTERESTS

Transfusion Medicine
Haemaoglobinopathies
Haemostasis
Haemo oncology
43

Scopus Publications

1179

Scholar Citations

18

Scholar h-index

28

Scholar i10-index

Scopus Publications

  • Seroprevalence, seroconversion, and mother-to-child transmission of dual and triplex infections of HIV, HBV, and HCV among Nigerian obstetric population: A national multicentre prospective cohort study
    George Uchenna Eleje, Hadiza Abdullahi Usman, Chinyere Ukamaka Onubogu, Preye Owen Fiebai, Godwin Otuodichinma Akaba, et al.
    Antiviral Therapy, 2025
    Objectives To determine seroprevalence, seroconversion, and mother-to-child transmission (MTCT) rates for dual and triplex infections of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) among pregnant women. Methods A multicentre prospective cohort study was conducted in six randomly selected tertiary hospitals from six geopolitical zones of Nigeria. Consenting participants were tested at recruitment for triplex infections and followed-up till delivery. Retests were performed at delivery for those who tested negative for all three infections/positive for only one. Polymerase chain reaction was used for validation while rapid test kits were employed for initial screening. Results Of the 2775 participants recruited, 13 (0.47%; 95% CI: 0.25%–0.80%) and 4 (0.14%; 95% CI: 0.04%–0.37%) were seropositive for dual and triplex infections, respectively. Dual infections revealed seroprevalences of 0.22% for HIV-HBV (6/2775; 95% CI: 0.08%–0.47%), 0.14% for HIV-HCV (4/2775; 95% CI: 0.04%–0.37%), and 0.11% for HBV-HCV (3/2775; 95% CI: 0.02%–0.32%). Multivariable analysis highlighted significant associations between HIV/HBV co-infection and religion (adjusted odds ratio (aOR): 0.068, 95% CI: 0.006–0.757) and house ownership (aOR): 1.65 × 10 –9 , 95% CI: 1.60 × 10 –9 –1.70 × 10 −9 ). Continuing our follow-up until delivery for 2403 initial participants, 2386 did not have dual or triplex infections at the start. Upon retesting at delivery, three of these women were seropositive for a dual infection of HIV and HBV, giving a seroconversion rate of 0.12% (95% CI: 0.03% to 0.37%). MTCT rate stood at 0% at 6-week post-delivery. Conclusion We observed a relatively low seroprevalence and seroconversion rates for dual and triplex infections of HIV, HBV, and HCV among pregnant women in Nigeria and no MTCT.
  • Adult Patients with HbS-Only Phenotype of Sickle Cell Disease Have a Decreased Arginine/Asymmetric Dimethylarginine Ratio
    Chiemelie Raluchukwu Onwasigwe, Angela Ogechukwu Ugwu, Anazoeze Jude Madu, Ikechukwu Okwudili Anigbogu, Chidiebele Michael Egolum
    Medical Principles and Practice, 2025
    Objective: Leg ulcer is the most common cutaneous manifestation of sickle cell disease (SCD). Asymmetric dimethylarginine (ADMA) inhibits nitric oxide synthase, reducing nitric oxide availability and causing endothelial dysfunction. This study examined the relationship between arginine/ADMA ratio and leg ulcers in SCD. Methods: This was a cross sectional analytical study of 90 adult subjects including, 30 ‘HbS only’ with leg ulcer, 30 ‘HbS only’ without leg ulcer and 30 HbAA subjects. Plasma Arginine and ADMA levels were measured by ELISA method. Results: Median Arginine level, ADMA level, and Arginine/ADMA ratio were 21.05µmol/L, 3.0 µmol/L, and 7.41 respectively, for HbS-Only with leg ulcer; 25.9 µmol/L, 2.8 µmol/L, and 9.6 respectively, for HbS-Only without leg ulcer; and 47.8 µmol/L, 1.0 µmol/L (CI: 1.0-1.2), and 48.5 respectively for HbAA subjects. Median plasma L-arginine level was significantly lower in HbS with leg ulcer compared to HbS without leg ulcer (p < 0.001) and HbAA subjects (p < 0.001)). Conversely, median plasma ADMA level was significantly higher in HbS-Only with leg ulcer compared to HbS without leg ulcer (p = 0.002), and HbAA subjects (p < 0.001). Median Arginine/ADMA ratio was significantly lower in HbS-only patients with leg ulcer. Conclusions: The HbS-only patients with leg ulcers have lower Arginine, higher ADMA and lower Arginine/ADMA ratio when compared to those without leg ulcers and HbAA controls. The prospective Arginine/ADMA ratio should be studied to screen patients with higher risks of leg ulcers that could be prevented with specifically targeted care.
  • Access and usage of formal financial services among small-scale cassava farmers in Enugu state, Nigeria
    Angela Ugwu, Angela Igweh, Joseph Odoh, Ginikanwa Ezeaku
    Turkish Journal of Agricultural Economics, 2024
    Purpose: Access to financial resources has been identified as one of the ways of boosting farm output, and this can be achieved through improving access to and usage of formal financial services. The study thus evaluated the effects of financial inclusion on cassava production among small-scale farmers in Enugu state, Nigeria.Methodology: A multi-stage sampling technique was employed in the selection of 162 cassava farmers in Enugu State. The data collected were analyzed using descriptive statistics, multiple regression analysis, and Likert scale rating Technique.Finding: Empirical results showed that the average of all respondents who participated in the survey was 43 years and 62.35% of the total respondents were males. Additionally, the result showed mean household size (4.75), mean years of cassava farming experience (5.86 years), and mean farm size (0.45 hectares). The majority (88.30%) of the farmers had access to a formal financial institution and the average amount saved in the last 12 months was ₦162,154.32. The multiple regression analysis showed that socioeconomic characteristics influencing cassava output are household, farming experience, farm size, farm income, and input cost. Additionally, financial inclusion positively influenced cassava output through access to formal financial institutions and level of savings.Originality: The findings revealed the positive effect access and usage of formal financial services have on the economy. Therefore, the study recommends that farmers be encouraged to improve their usage of formal financial services such as improving their savings levels at banks and banks to reduce charges on formal financial services.
  • The role of immune-inflammatory markers in children with complicated and uncomplicated malaria in Enugu, Nigeria
    Angela Ogechukwu Ugwu, Rebecca Chinyelu Chukwuanukwu, Friday Alfred Ehiaghe, Emmanuel Onyebuchi Ugwu
    BMC Immunology, 2024
    Background There is currently insufficient data regarding immune parameters and relationship with severity of malaria infection in Enugu, Nigeria where the economic and social costs of the disease and its management are extremely high. This study was conducted to determine the relationship between malaria severity and some immune-inflammatory markers among malaria-infected children in Enugu, Nigeria. Methods The study adopted a case control design. Eligible children were categorized into three groups — complicated, uncomplicated and healthy children. Pro-inflammatory cytokines –interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α); and anti-inflammatory cytokine — interleukin-10 (IL-10) were assayed using enzyme-linked immunosorbent assay (ELISA) technique, while immune cell ratios — neutrophil lymphocyte ratio (NLR) and monocyte lymphocyte ratio (MLR) were calculated from full blood count results. Results The overall mean age of the participants was 7.3 ± 3.4 (range: 6 months − 12 years) and the male-female ratio was 1:1. There was no significant difference between the ages of the three groups (P = 0.44). The Mean levels of IFN-γ, TNF-α, and NLR were higher in complicated than uncomplicated malaria (266.9 ± 66.3pg/ml vs. 62.5 ± 6.4pg/ml, p < 0.001; 140.3 ± 30.0pg/ml vs. 42.0 ± 9.0pg/ml, p < 0.001; and 32.9 ± 16.2pg/ml vs. 17.8 ± 6.0pg/ml, p < 0.001, respectively); and higher in uncomplicated malaria than healthy children (62.5 ± 6.4pg/ml vs. 40.6 ± 9.1pg/ml, p < 0.001; 42.0 ± 9.0pg/ml vs. 105.7 ± 32.1, p < 0.001; 17.8 ± 6.0pg/ml vs. 18.7 ± 6.2pg/ml, p < 0.001, respectively). On the other hand, the mean level of IL-10 is higher in uncomplicated than complicated malaria (105.73 ± 32.06pg/ml vs. 40.60 ± 9.11pg/ml, p < 0.001). There was a positive correlation between NLR and IFN-γ (r = 0.815; p = 0.003), as well as NLR and TNF-α (r = 0.745; p = 0.002). Conclusion Complicated malaria is associated with higher levels of pro-inflammatory cytokines while uncomplicated malaria is associated with higher levels of anti-inflammatory cytokines. NLR correlates positively with pro-inflammatory cytokines, and could be useful in evaluation for the severity of malaria infection.
  • Multidisciplinary approach to obstetric disseminated intravascular coagulopathy management in low-income country: A survey
    Theresa U. Nwagha, Helen C. Okoye, Angela O. Ugwu, Augustine N. Duru, Ifeanyi E. Menuba, et al.
    International Journal of Gynecology and Obstetrics, 2024
    ObjectiveTo assess the uptake of a multidisciplinary team approach in obstetric disseminated intravascular coagulopathy (DIC) management in a low‐ to middle‐income country.MethodsA cross‐sectional observational study, in which a semi‐structured and pre‐tested questionnaire was used to collect data on the uptake by Nigerian obstetricians of the multidisciplinary team approach to obstetric DIC management.ResultsA total of 171 obstetricians responded, 82 (48.0%) were consultants and 89 (52.0%) were specialist registrars. Most (165; 96.5%) practiced in tertiary healthcare facilities and the multidisciplinary team approach was the most preferred (162; 94.7%) management approach. In all, 142 (83.0%) supported the invitation of hematologists always in the management whereas 115 (67.3%) participants recommended that involvement of specialists in the treatment should be when clinical presentation was suggestive of DIC. No significant association existed between years of obstetric practice and adoption of a multidisciplinary team‐based approach (χ2 = 9.590; P = 0.252).ConclusionA multidisciplinary approach is widely adopted in the management of obstetric DIC, with hematologists being a key member of the team.
  • Effects of Maternal Dyslipidemia on Maternal and Perinatal Outcomes in Enugu, Southeast Nigeria: A Prospective Cohort Study
    CE Obodo, PU Agu, EO Ugwu, HU Ezegwui, PO Nkwo, et al.
    Nigerian Journal of Clinical Practice, 2024
    Background: Maternal dyslipidemia is one of the consistent metabolic changes during pregnancy. There is a controversy as to whether maternal lipid disturbances in early pregnancy are associated with adverse maternal and perinatal outcome. Aim: To determine the effects of maternal dyslipidemia on maternal and perinatal outcomes. Methods: A prospective observational cohort study of eligible pregnant women attending antenatal clinic (ANC) at two tertiary hospitals in Southeast Nigeria. The attendees blood samples were collected for lipid profile analysis and those who met the criteria for dyslipidemia constituted the study (exposed) group, while those with normal lipid levels were the control (unexposed group). Both groups were followed up throughout pregnancy and in labor to determine the pregnancy and perinatal outcomes. Results: Compared with pregnant women with normal lipid profile, those with dyslipidemia were at higher risk of low birth weight (LBW) (RR: 9.40, CI 95%: 1.3-70.2, P = 0.005), intrauterine fetal death (IUFD) (RR: 5.98; 95% CI: 0.8-46.9; P = 0.04), still birth (RR: 6.84, CI 95%: 8.9-52.7, P = 0.03), and birth asphyxia (RR: 10.26, CI 95%:1.4-76.0, P = 0.003). Conclusion: Maternal dyslipidemia is associated with some adverse perinatal outcomes such as LBW, IUFD, still birth, and birth asphyxia. These findings would guide in the care of pregnant women with dyslipidemia.
  • Blood donation practices, processing and utilisation of blood components in government tertiary hospitals in Nigeria: a multicentre cooperative study
    Garba Umar, Ibrahim Abdulqadir, Ngozi Ugwu, Titilope Adeyemo, Nabila Yau, et al.
    International Health, 2024
    Background Timely access to safe blood and blood components is still a challenge in Nigeria. This study aimed to determine blood donation practices, processing and utilization of blood components across government tertiary hospitals (THs) in Nigeria. Methods This was a descriptive cross-sectional study done in Nigeria in June–July 2020. Data were analysed with SPSS version 21.0. Results Data were collected from 50 THs. The majority (68%) of the THs lack facilities for blood component preparation and only 18% and 32% provide cryoprecipitate and platelet concentrate, respectively. Whole blood was most commonly requested (57.04%). All facilities tested blood for HIV, HBV and HCV, but the majority (23 [46%]) employed rapid screening tests alone and nucleic acid testing was not available in any hospitals. The manual method was the most common method of compatibility testing in 90% (45/50) and none of the THs routinely perform extended red cell typing. The average time to process routine, emergency and uncross-matched requests were a mean of 109.58±79.76 min (range 45.00–360.00), 41.62±25.23 (10.00–240.00) and 11.09±4.92 (2.00–20.00), respectively. Conclusion Facilities for blood component preparation were not widely available. Concerned government authorities should provide facilities for blood component preparation.
  • Frequency of red blood cell allo-immunization in transfused patients with sickle cell disease in Africa: a systematic review with meta-analysis
    Theresa Ukamaka Nwagha, Angela Ogechukwu Ugwu, Martins Nweke
    African Health Sciences, 2024
    Background and Objectives: Blood transfusion is an effective and proven treatment for some severe complications of sickle cell disease. Recurrent transfusions have put patients with sickle cell disease at risk of developing antibodies against the various antigens they were exposed to. This study aims to investigate the frequency of red blood cell alloimmunization in patients with sickle disease in Africa.Materials and Methods: This is a systematic review of peer-reviewed and published literature. The review was conducted consistent with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist.Data sources for the review include MEDLINE, PubMed, AJOL, CINAHL, Psych-Info and Academic Search Complete. Included in this review are articles that reported the frequency/prevalence of red blood cell alloimmunization in sickle cell disease patients in Africa. Eligible studies were subjected to independent full-text screening and data extraction. Risk of bias assessment was conducted with the aid of the mixed method appraisal tool. We employed a random-effects model of meta-analysis to estimate the pooled prevalence. We computed Cochrane’s Q statistics and I2 and prediction interval to quantify heterogeneity in effect size.Results: The prevalence estimates range from 2.6% to 29%. Pooled prevalence was estimated to be 12.1% (95% CI 8.1 to 17.7), with significant heterogeneity (I2= 91.83; PI = 2 to 54%).Conclusion: The frequency of red cell alloantibody varies considerably in Africa.Keywords: Systematic review; red blood cell; alloimmunization; sickle cell disease; Africa.
  • Healthcare practitioners’ Knowledge and Awareness on current guideline for management of hypertension in Nigeria: A cross-sectional web-based survey
    Ibom Medical Journal, 2024
  • Impact of binet staging versus tumour bulk on treatment outcome in chronic lymphocytic leukaemia
    Anazoeze Jude Madu, Helen Chioma Okoye, Ebele Adaobi Muoghalu, Angela Ogechukwu Ugwu, Augustine Nwakuche Duru, et al.
    Nigerian Postgraduate Medical Journal, 2024
    Background: Most of the predictive tools put up to prognosticate treatment outcomes in patients with chronic lymphocytic leukaemia (CLL) are not easily available and affordable in our resource-constrained environment. Aim: The aim of this study was to evaluate the impact of staging and some tumour bulk on treatment outcomes of persons with CLL, Enugu, Nigeria. Patients and Methods: This is a 10-year review of the CLL data from the haemato-oncology unit of a Nigerian tertiary hospital to evaluate the impact of staging and tumour bulk indicators. Data were retrieved from the case notes of 102 patients with CLL receiving care at the facility. Data of interest include basic demographic variables, clinical features including spleen size and disease staging and blood counts. Statistical analysis was done using SPSS version 22. Results: The median absolute lymphocyte count (ALC) was 108.05 (confidence interval [CI] = 50.8–201.3, interquartile range [IQR] = 124.4) ×109/L, and duration of survival for the study cohort was 5.5 (CI = 3.5–31.9, IQR = 27) months. Majority (69, 79.3%) were in Stage C. The Binet stage showed a significant association with the ALC (r = 0.338; P = 0.002) but not with spleen size (r = 0.198; P = 0.056). The duration of survival only showed a significant inverse relationship with the ALC (r = 0.35, P = 0.006) but with neither the Binet stage (r = 0.103, P = 0.431) nor spleen size (r = 0.184, P = 0.116). Conclusion: In CLL patients, ALC at presentation correlates with the duration of survival. We recommend that the ALC at presentation be used as a prognostic marker in our clime.
  • Antivirals for prevention of hepatitis B virus mother-to-child transmission in human immunodeficiency virus positive pregnant women co-infected with hepatitis B virus
    Emmanuel O Ugwu, George U Eleje, Angela O Ugwu, Uchenna I Nwagha, Joseph I Ikechebelu, et al.
    Cochrane Database of Systematic Reviews, 2023
  • Cerebral artery conditional blood velocity in sickle cell disease: A multicentre study and evidence for active treatment
    Emmanuel Modebe, Charles Nonyelu, Augustine Duru, Osita Ezenwosu, Barth Chukwu, et al.
    Archives of Disease in Childhood, 2023
  • Efficacy and safety of Mojeaga remedy in combination with conventional oral iron therapy for correcting anemia in obstetric population: A phase II randomized pilot clinical trial
    George Uchenna Eleje, Ifeanyichukwu Uzoma Ezebialu, Joseph Tochukwu Enebe, Nnanyelugo Chima Ezeora, Emmanuel Onyebuchi Ugwu, et al.
    Plos One, 2023
  • Antichlamydia Antibodies and Sperm Quality among Male Partners of Infertile Couples in Nigeria
    PC Udealor, AO Olibe, EO Ugwu, CA Iyoke, AO Ugwu, et al.
    Nigerian Journal of Clinical Practice, 2023
  • Iron supplementation and blood donation in Nigeria: Effect on Hemoglobin, red cell indices, and iron stores - The ranferon™ study
    T. Nwagha, A. Ugwu, Chinenye Nkemakolam Nwaekpe
    Annals of African Medicine, 2023
  • Effectiveness of blood utilization across departments in a tertiary health institution
    Ikechukwu Okwudili Anigbogu, Ebele Dumebi Muoghalu, Anazoeze Jude Madu, Charles Emeka Nonyelu, Helen Chioma Okoye, et al.
    Acta Haematologica Polonica, 2023
  • Renal Biomarkers in Pre-Eclampsia and their Associations with Severity of Pre-Eclampsia
    Paschalina C. Ezechukwu, Emmanuel O. Ugwu, Samuel N. Obi, George U. Eleje, Polycarp U. Agu, et al.
    International Journal of Medicine and Health Development, 2023
  • A Systematic Review and Meta-Analysis of the Prevalence of Triplex Infections (Combined Human Immunodeficiency Virus, Hepatitis B Virus, and Hepatitis C Virus) among Pregnant Women in Nigeria
    George Uchenna Eleje, Olabisi Morebise Loto, Hadiza Abdullahi Usman, Chinyere Ukamaka Onubogu, Preye Owen Fiebai, et al.
    Obstetrics and Gynecology International, 2023
  • Venous Thromboembolism: Knowledge and Awareness among Students of Faculties of Medicine in Southeast Nigeria - A Need for Curriculum Review
    Helen C. Okoye, Theresa U. Nwagha, Lisa I. Eweputanna, Chilota C. Efobi, Eyiuche D. Ezigbo, et al.
    International Journal of Medicine and Health Development, 2022
  • Evaluation of the Clinico-laboratory Manifestations of Newly Diagnosed Multiple Myeloma
    Angela Ogechukwu Ugwu
    International Journal of Medicine and Health Development, 2022
  • Cesarean section rate and outcomes during and before the first wave of COVID-19 pandemic
    George Uchenna Eleje, Emmanuel Onyebuchi Ugwu, Joseph Tochukwu Enebe, Chukwuemeka Chukwubuikem Okoro, Boniface Chukwuneme Okpala, et al.
    Sage Open Medicine, 2022
  • Does Sickle Cell Disease Protect against HIV Infection: A Systematic Review
    Theresa Ukamaka Nwagha, Angela Ogechukwu Ugwu, Martins Nweke
    Medical Principles and Practice, 2022
  • Gender Differences in the Complications of Sickle Cell Anemia
    Angela O. Ugwu
    International Journal of Medicine and Health Development, 2022
  • Phenotypic characterisation and associations of leg ulcers in adult sickle cell patients
    Anazoeze Madu, Kenechi Madu, Ikechukwu Anigbogu, Angela Ogechukwu Ugwu, Vincent A. Okwulehie, et al.
    Wound Repair and Regeneration, 2022
  • Diagnosis and treatment of bbstetrics disseminated intravascular coagulation in resource limited settings
    Helen C Okoye, Theresa U Nwagha, Angela O Ugwu, Ifeanyi E Menuba, Augustine N Duru, et al.
    African Health Sciences, 2022

RECENT SCHOLAR PUBLICATIONS

  • Inadequate and maldistribution of critical personnel for blood transfusion services, a potential threat to blood safety in Nigeria: a multicenter cooperative study.
    I Abdulqadir, G Umar, N Yau, AA Hassan, O Ayodele, A Musa, ...
    Nigerian Journal of Haematology 9 (1) , 2025
    2025
  • Adult Patients with HbS-Only Phenotype of Sickle Cell Disease Have a Decreased Arginine/Asymmetric Dimethylarginine Ratio
    CR Onwasigwe, AO Ugwu, AJ Madu, IO Anigbogu, CM Egolum
    Medical Principles and Practice 34 (5), 483-490 , 2025
    2025
  • ORIGINAL Population Survey on Contributing Factors to Sustained Prevalence of Sickle Cell Disease in Enugu, Nigeria: West Afr J Med. 2025 January; 42 (1): 44-51 PMID: 40544512
    AO Ugwu, CJ Okamkpa, CS Anigbo, EA Muoghalu, OI Obodo, ...
    West Africa Journal of Medicine 42 (1), 44-51 , 2025
    2025
    Citations: 1
  • Investigating serum levels of IL-6 and TNF alpha, and the risk of thrombosis in newly diagnosed chemotherapy naïve obese cancer patients
    AO Ugwu, ID Nnakenyi, CJ Okwor
    Nigerian Medical Journal: Journal of the Nigeria Medical Association 66 (2), 761 , 2025
    2025
    Citations: 1
  • Seroprevalence, seroconversion, and mother-to-child transmission of dual and triplex infections of HIV, HBV, and HCV among Nigerian obstetric population: A national multicentre …
    GU Eleje, HA Usman, CU Onubogu, PO Fiebai, GO Akaba, A Rabiu, ...
    Antiviral Therapy 30 (2), 13596535251333259 , 2025
    2025
    Citations: 4
  • Hematological Profile and Prevalence of Bloodborne Viruses Among Pregnant Women Attending Antenatal Clinic in a Tertiary Military Hospital in Lagos, Southwest of Nigeria
    SI Omisakin, GS Ogoh, AS Ayeni, AO Ugwu, AO Ugwu, C Odo, OE Otokiti, ...
    2025
    Citations: 3
  • Quality Assurance and Blood Security in Blood Transfusion Practice in Nigeria: A Multi-Centre Study
    G Umar, N Ugwu, I Abdulqadir, S Yuguda, T Adeyemo, C Ukoma, ...
    Orient Journal of Medicine 37 (1-2), 17-25 , 2025
    2025
  • Access and usage of formal financial services among small-scale cassava farmers for productivity in Enugu state, Nigeria.
    A Ugwu, A Igweh, J Odoh, G Ezeaku
    Tarım Ekonomisi Dergisi 30 (2), 183-196 , 2024
    2024
    Citations: 2
  • Access and usage of formal financial services among small-scale cassava farmers in Enugu state, Nigeria.
    A Ugwu, A Igweh, J Odoh, G Ezeaku
    Turkish Journal of Agricultural Economics 30 (2) , 2024
    2024
  • ORIGINAL: Association Between Anti-Chlamydial Antibodies and Tubal Factor Infertility in South Eastern Nigeria: West Afr J Med. 2024 November; 41 (11): 1091-1096 PMID: 40221906
    JC Akabueze, PU Agu, EO Ugwu, SN Obi, UU Aniebue, GU Eleje, ...
    West Africa Journal of Medicine 41 (11), 1091-1096 , 2024
    2024
    Citations: 1
  • Multidisciplinary approach to obstetric disseminated intravascular coagulopathy management in low‐income country: A survey
    TU Nwagha, HC Okoye, AO Ugwu, AN Duru, IE Menuba, EO Ugwu, ...
    International Journal of Gynecology & Obstetrics 167 (2), 779-783 , 2024
    2024
  • Blood donation practices, processing and utilisation of blood components in government tertiary hospitals in Nigeria: a multicentre cooperative study
    G Umar, I Abdulqadir, N Ugwu, T Adeyemo, N Yau, A Hassan, J Olaniyi, ...
    International Health 16 (6), 636-641 , 2024
    2024
    Citations: 4
  • Frequency of red blood cell allo-immunization in transfused patients with sickle cell disease in Africa: a systematic review with meta-analysis
    TU Nwagha, AO Ugwu, M Nweke
    African Health Sciences 24 (3), 417-429 , 2024
    2024
    Citations: 2
  • Attributes of pathological fractures in a Nigerian myeloma cohort
    AN Duru, CE Nonyelu, AJ Madu, HC Okoye, AO Ugwu, IO Anigbogu, ...
    Annals of Clinical and Biomedical Research 5 (2) , 2024
    2024
  • Healthcare practitioners’ Knowledge and Awareness on current guideline for management of hypertension in Nigeria: A cross-sectional web-based survey
    TT Shogade, EE Ekpe, ST Engmann, AU Udosen, AO Ajibare, ...
    Ibom Medical Journal 17 (3), 484-491 , 2024
    2024
    Citations: 1
  • ORIGINAL: Effectiveness of Monthly Versus Two-Dose Regimen of Sulphadoxine-Pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Southeastern Nigeria …
    GU Odoh, PU Agu, EO Ugwu, CC Dim, SN Obi, JE Nnagbo, MI Eze, ...
    West Africa Journal of Medicine 41 (8), 860-867 , 2024
    2024
    Citations: 1
  • ORIGINAL: Use of Prophylactic Parenteral Tranexamic Acid for Reduction of Blood Loss During and After Caesarean Section: A Double-Blind Randomized Controlled Study: West Afr J …
    AV Ndubuisi, PU Agu, EO Ugwu, SN Obi, GU Eleje, MI Eze, KE Ekwuazi, ...
    West Africa Journal of Medicine 41 (7), 810-817 , 2024
    2024
    Citations: 2
  • The role of immune-inflammatory markers in children with complicated and uncomplicated malaria in Enugu, Nigeria
    AO Ugwu, RC Chukwuanukwu, FA Ehiaghe, EO Ugwu
    BMC immunology 25 (1), 47 , 2024
    2024
    Citations: 9
  • Frequency of red blood cell allo-immunization in transfused patients with sickle cell disease in Africa
    TU Nwagha, AO Ugwu, MC Nweke
    Makerere University Medical School , 2024
    2024
  • Beyond malaria: A rare case of Tardive dyskinesia-like syn-drome in antimalaria therapy
    EC Ezema, T Okoye, O Agazie, VO Ugwu, AO Ugwu, C Okeke-Moffatt, ...
    J Clin Images Med Case Rep 5 (5), 3025 , 2024
    2024

MOST CITED SCHOLAR PUBLICATIONS

  • Determinants of compliance to iron supplementation among pregnant women in Enugu, Southeastern Nigeria
    EO Ugwu, AO Olibe, SN Obi, AO Ugwu
    Nigerian journal of clinical practice 17 (5), 608-612 , 2014
    2014
    Citations: 166
  • A five-year survey of caesarean delivery at a Nigerian tertiary hospital
    EOV Ugwu, KCE Obioha, OA Okezie, AO Ugwu
    Annals of medical and health sciences research 1 (1), 77 , 2011
    2011
    Citations: 133
  • Acceptability of human papilloma virus vaccine and cervical cancer screening among female health-care workers in Enugu, Southeast Nigeria
    EO Ugwu, SN Obi, PC Ezechukwu, II Okafor, AO Ugwu
    Nigerian journal of clinical practice 16 (2), 249-252 , 2013
    2013
    Citations: 105
  • Utilization of insecticide treated nets among pregnant women in Enugu, South Eastern Nigeria
    EO Ugwu, PC Ezechukwu, SN Obi, AO Ugwu, TC Okeke
    Nigerian journal of clinical practice 16 (3), 292-296 , 2013
    2013
    Citations: 78
  • Pattern of blood donation and characteristics of blood donors in Enugu, Southeast Nigeria
    AO Ugwu, AJ Madu, CC Efobi, OG Ibegbulam
    Nigerian journal of clinical practice 21 (11), 1438-1443 , 2018
    2018
    Citations: 66
  • Patter of Gynaecological Cancers in University of Nigeria Teaching Hospital, Enugu, South Eastern Nigeria
    EOV Ugwu, SE Iferikigwe, TC Okeke, AO Ugwu, OA Okezie, PU Agu
    Nigerian Journal of Medicine 20 (2), 266-269 , 2011
    2011
    Citations: 59
  • Pilot study of omega‐3 fatty acid supplements in sickle cell disease
    I Okpala, O Ibegbulam, A Duru, S Ocheni, I Emodi, A Ikefuna, G Umar, ...
    Apmis 119 (7), 442-448 , 2011
    2011
    Citations: 46
  • Stroke prevalence amongst sickle cell disease patients in Nigeria: a multi-centre study
    MA Jude, GN Aliyu, AM Nalado, KU Garba, FO Florence, A Hassan, ...
    African Health Sciences 14 (2), 446 , 2014
    2014
    Citations: 41
  • Incidence, pattern and management of ovarian cancer at a tertiary medical center in Enugu, South East Nigeria
    CA Iyoke, GO Ugwu, EC Ezugwu, N Onah, O Ugwu, O Okafor
    Annals of Medical and Health Sciences Research 3 (3), 417 , 2013
    2013
    Citations: 40
  • Cesarean section rate and outcomes during and before the first wave of COVID-19 pandemic
    GU Eleje, EO Ugwu, JT Enebe, CC Okoro, BC Okpala, NC Ezeora, ...
    SAGE Open Medicine 10, 20503121221085453 , 2022
    2022
    Citations: 36
  • Avascular necrosis in sickle cell (homozygous S) patients: Predictive clinical and laboratory indices
    AJ Madu, AK Madu, GK Umar, K Ibekwe, A Duru, AO Ugwu
    Nigerian Journal of Clinical Practice 17 (1), 86-89 , 2014
    2014
    Citations: 30
  • Malaria and anaemia in pregnancy: a cross-sectional study of pregnant women in rural communities of Southeastern Nigeria
    EO Ugwu, CC Dim, BS Uzochukwu, EI Iloghalu, AO Ugwu
    International Health 6 (2), 130-137 , 2014
    2014
    Citations: 28
  • Sexual practices of people living with HIV in South Eastern Nigeria
    J Ikechebelu, S Mbamara, N Joe-Ikechebebelu, A Ezenwabachili
    Nigerian Journal of Clinical Practice 12 (4) , 2009
    2009
    Citations: 26
  • Hyperhaemolytic syndrome in sickle cell disease: clearing the cobwebs
    AJ Madu, AO Ugwu, C Efobi
    Medical Principles and Practice 30 (3), 236-243 , 2021
    2021
    Citations: 24
  • Perception of problem based learning versus conventional teaching methods by clinical medical students in Nigeria
    HC Okoye, IA Meka, AO Ugwu, IA Yahaya, O Otokunefor, OO Ojo, ...
    The Pan African Medical Journal 33, 311 , 2019
    2019
    Citations: 22
  • Anti‑malaria prescription in pregnancy among general practitioners in Enugu state, south east Nigeria
    EO Ugwu, ES Iferikigwe, SN Obi, AO Ugwu, PU Agu, OA Okezie
    Nigerian Medical Journal 54 (2) , 2013
    2013
    Citations: 21
  • Blood transfusion in Sub-Saharan Africa: Historical perspective, clinical drivers of demand and strategies for increasing availability
    AO Ugwu, AJ Madu, IO Anigbogu
    Afr Sanguine 23 (1), 14-20 , 2021
    2021
    Citations: 19
  • Clinical and laboratory predictors of frequency of painful crises among sickle cell anaemia patients in Nigeria
    AO Ugwu, OG Ibegbulam, TU Nwagha, AJ Madu, S Ocheni, I Okpala
    Journal of Clinical and Diagnostic Research: JCDR 11 (6), EC22 , 2017
    2017
    Citations: 18
  • Levels of Maternal Serum Alpha-fetoprotein and Beta Human Chorionic Gonadotropin in HIV Seropositive Pregnant Women Attending Antenatal Care at Nnamdi Azikiwe University …
    CH Udeogu, MC Ugwu, J Okwara, AC Ohale, OC Ike, NC Amadi, O Ugwu, ...
    J. Adv. Med. Med. Res, 32-38 , 2021
    2021
    Citations: 15
  • Cerebral artery conditional blood velocity in sickle cell disease: a multicentre study and evidence for active treatment
    E Modebe, C Nonyelu, A Duru, O Ezenwosu, B Chukwu, A Madu, ...
    Archives of Disease in Childhood 108 (6), 440-444 , 2023
    2023
    Citations: 14