Intentional Insulin Omission (Diabulimia) in Patients with Insulin-Dependent Diabetes: An Eating Disorder? A Systematic Review Maria Benedetta Anesini, Mario Pinto, Michela Bellezza, Georgios D. Kotzalidis, Tommaso Callovini, Silvia Montanari, Camilla Scialpi, Gabriele Sani, Lorenzo Moccia, Delfina Janiri Journal of Clinical Medicine, 2026 Background/Objectives: Intentional insulin omission (IIO), commonly referred to as diabulimia, is a high-risk behavioural phenomenon observed mainly in adolescents and young adults with type 1 diabetes mellitus (T1D). Defined as the deliberate reduction or omission of insulin to influence body weight, IIO lies at the intersection of metabolic management and eating disorder psychopathology. Despite serious health risks, including diabetic ketoacidosis, microvascular complications, and increased mortality, it remains under-recognised due to stigma, diagnostic ambiguity, and overlap with routine diabetes self-management. This review aimed to examine the prevalence, psychological mechanisms, and clinical consequences of IIO. Methods: On 1 April 2026, we conducted a systematic search of PubMed, Scopus, APA PsycInfo/PsycArticles and Cinahl for studies investigating intentional insulin omission and related metabolic and psychological outcomes in T1D. Clinical and epidemiological studies assessing prevalence, risk factors, and interventions were included. Results: Twenty-nine studies met the inclusion criteria. Prevalence estimates ranged from 20% to 45%, with higher risk among females, adolescents, and individuals experiencing diabetes-related distress or body dissatisfaction. Psychological factors—including fear of weight gain, emotion dysregulation, depressive symptoms, and identity conflicts—were associated with IIO onset and maintenance. IIO was consistently linked to poor glycaemic control, elevated HbA1c levels, and adverse metabolic and psychological outcomes. Screening tools such as the Diabetes Eating Problem Survey–Revised (DEPS-R) may support early identification, while effective management requires integrated multidisciplinary care. Conclusions: Although IIO is not formally classified as an eating disorder in current diagnostic systems, it shares important psychopathological features with eating disorders and may represent a diabetes-specific disordered eating behaviour with life-threatening consequences.
Lifetime Mixed Depression and Childhood Trauma in Individuals With Bipolar Disorders Francesca Bardi, Mario Pinto, Alessio Simonetti, Marco Di Nicola, Marianna Mazza, Giovanni Manfredi, Georgios D. Kotzalidis, Gabriele Sani, Delfina Janiri Acta Psychiatrica Scandinavica, 2026 Background and Aims Mixed Depression (MxD), characterized by the co‐occurrence of depressive and excitatory symptoms, is a prevalent yet often underdiagnosed presentation in bipolar disorders (BD), with significant implications for prognosis and treatment. Childhood trauma is a key environmental risk factor associated with a more severe course of BD, as it influences its onset, progression, and clinical presentation. To date, no studies have specifically investigated the relationship between lifetime childhood trauma and lifetime MxD in individuals with BD. The aim of our study was to address this gap in a large and well‐characterized sample of patients with BD type I and type II. Methods A total of 376 individuals, 220 euthymic outpatients with BD (MxD = 100, non‐MxD = 120) and 156 healthy controls (HC), were enrolled. Childhood trauma was assessed using the Childhood Trauma Questionnaire (CTQ). Lifetime MxD was identified according to the Koukopoulos criteria. The relationship between childhood trauma and MxD was evaluated using two different multivariate models. Results The first model (Wilks' Lambda = 0.834, p < 0.001) revealed that BD patients with lifetime MxD reported significantly higher CTQ total scores compared to both non‐MxD ( p = 0.029) and HC ( p < 0.001). When examining childhood trauma subtypes, BD patients with MxD reported significantly higher emotional abuse scores than those without MxD ( p < 0.001). Furthermore, compared to HC, the MxD group showed significantly elevated scores in emotional abuse, emotional neglect, and physical abuse (all p < 0.001). The non‐MxD group scored higher than HC on physical abuse ( p = 0.008) and physical neglect ( p < 0.001). Regression analyses confirmed specifically emotional abuse as a significant predictor of lifetime MxD. Conclusions The findings demonstrate a strong association between childhood trauma, particularly emotional abuse, and lifetime MxD. These results underscore the significance of childhood trauma as a key predictor of clinical outcomes in BD.
Orexins, Psychosis, and Antipsychotics: A Systematic Review of Studies of Orexin Levels and the Effects of Dual Orexin Receptor Antagonists (DORAs) Stella Margoni, Senad Hasaj, Guglielmo Donofrio, Georgios D. Kotzalidis, Tommaso Callovini, Mario Pinto, Camilla Scialpi, Matteo Bucci, Maria Benedetta Anesini, Gabriele Sani, Lorenzo Moccia, Delfina Janiri Brain Sciences, 2026 Background/Objectives: Schizophrenia is a severe psychiatric disorder frequently characterised by sleep and circadian disturbances, which are closely linked to cognitive dysfunction, symptom exacerbation, and poor functional outcomes. A growing body of evidence implicates the orexin (hypocretin) system—an essential regulator of arousal, sleep–wake stability, metabolic processes, and motivated behaviour—in the pathophysiology and treatment response of psychotic disorders. We aimed to investigate the relationships between the orexinergic system and psychoses. Methods: On 3 March 2026, we searched the PubMed, Scopus, PsycInfo/Articles and Cinahl databases for studies dealing with the orexin system and psychotic disorders and treatment response. Results: We found 20 eligible studies reporting variable and inconsistent alterations in orexin signalling in patients with schizophrenia. Studies were mostly cross-sectional and heterogeneous in design. Antipsychotic medications interfere with orexin-dependent pathways, potentially contributing to both therapeutic effects and adverse outcomes such as sleep disruption and metabolic dysregulation. Conclusions: While evidence from preclinical studies could point to an influence of dopaminergic activity through orexinergic mechanisms, with possible attenuation of antipsychotic-induced motor side effects and improvement of attentional deficits associated with NMDA receptor hypofunction, the utility of dual orexin receptor antagonists (DORAs) in psychoses is unclear. Despite the high prevalence of insomnia in schizophrenia, its pharmacological management remains suboptimal, with current treatments often limited by reduced efficacy or tolerability concerns. DORAs, which are currently approved medications for the treatment of insomnia, represent a novel and mechanistically distinct therapeutic option that may improve sleep while modulating arousal- and cognition-related circuits relevant to psychosis.
“Summertime sadness”: Striatal dopamine binding decreases during warmer seasons in patients with severe depression Antonio Maria D’Onofrio, Daniela Di Giuda, Eleonora Maggio, Daniele Antonio Pizzuto, Fabrizio Cocciolillo, Federica Cavallo, Rosaria Calia, Alessio Simonetti, Delfina Janiri, Alexia Koukopoulos, Mauro Pettorruso, Giovanni Martinotti, Gabriele Sani, Giovanni Camardese Psychiatry Research Neuroimaging, 2026 • No overall seasonal difference in striatal DAT between fall–winter and spring–summer • Severe depression (HAMD > 25) shows lower left putamen DAT, accentuated in spring–summer • Psychomotor retardation (DRRS > 18) links to reduced left putamen DAT, extending pan-striatal in spring–summer • Suicidal ideation associates with decreased bilateral putamen DAT • Anhedonia severity is higher in fall–winter : Seasonal changes, particularly increased daylight exposure, are known to influence dopamine transporter (DAT) availability, potentially affecting mood disorders such as major depressive disorder (MDD). This study aimed to evaluate seasonal variations in the striatum using ¹²³I-FP-CIT SPECT in patients with MDD, and examine associations with specific psychopathological symptoms. : In this retrospective study, DAT SPECT scans from 85 patients with MDD were analyzed according to the season of imaging—fall-winter (FW) or spring-summer (SS). Psychometric assessments included the Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), Snaith-Hamilton Pleasure Scale (SHAPS), and Depression Retardation Rating Scale (DRRS). : No overall differences in DAT availability were observed between FW and SS. However, anhedonia levels were higher in FW (p = 0.050). Patients with severe depression (HAMD ≥ 25) showed lower DAT availability in the left putamen, especially during SS (p = 0.014). Patients with marked psychomotor retardation (DRRS ≥ 18) exhibited reduced DAT availability in the left putamen (p = 0.002), with further reductions across all striatal regions during SS. Patients with suicidal ideation showed decreased DAT in the right (p = 0.029) and left putamen (p = 0.015). A negative correlation was found between DRRS scores and left putamen DAT availability (p = 0.034). : Reduced DAT availability is associated with key depressive symptoms, notably psychomotor retardation and suicidal ideation. Seasonal effects, especially in the SS period, may exacerbate dopaminergic dysregulation. These findings support integrating seasonal and neurobiological factors in the assessment and management of severe MDD.
Combination of Antidepressants and Chemotherapeutic Agents to Overcome P-Glycoprotein-Mediated Resistance in Cancer Patients: A Systematic Review Antonio Restaino, Mario Pinto, Giulio Carriero, Antonio Maria D’Onofrio, Silvia Montanari, Delfina Janiri, Giovanni Camardese, Lorenzo Moccia, Gabriele Sani, Alessio Simonetti Medical Sciences, 2026 Background/Objectives: P-glycoprotein (P-gp, ABCB1/MDR1) is a key ATP-binding cassette transporter involved in multidrug resistance in cancer, limiting intracellular accumulation of various chemotherapeutic (CT) agents. Several antidepressants (ADs) have been shown to modulate P-gp function. This dual pharmacological profile raises the possibility of repurposing ADs as chemosensitizers to enhance anticancer drug efficacy. The objective of this review was to summarize the available evidence on the combined use of ADs and chemotherapeutics to overcome P-gp-mediated resistance. Methods: A systematic search was performed in PubMed, Scopus, and PsycInfo/PsycArticles databases using a comprehensive search string combining terms for P-gp, ADs, chemotherapy, and drug resistance. Inclusion criteria were preclinical or clinical studies investigating the effect of ADs in combination with chemotherapeutics on P-gp-mediated resistance in cancer models. Eleven relevant studies were identified and qualitatively analyzed. Results: Across diverse cancer models, including colon, breast, and multidrug-resistant cell lines, several ADs significantly enhanced the cytotoxicity of many chemotherapeutic agents. The proposed mechanisms involved downregulation of P-gp expression, inhibition of efflux activity, and increased intracellular drug accumulation. Conclusions: The combination of ADs with CT agents shows promising potential in overcoming P-gp-mediated multidrug resistance, enhancing antitumor efficacy in preclinical models. Further translational and clinical research is needed to validate these findings, optimize dosing strategies, and assess the risk–benefit profile in cancer patients, particularly those with comorbid depressive disorders.
Late-Onset Depression in an Aging World: A Multidimensional Perspective on Risks, Mechanisms, and Treatment Antonio Maria D’Onofrio, Gaspare Filippo Ferrajoli, Lodovico Maria Balzoni, Marco Massetti, Andrea Zanzarri, Giuseppe Marano, Marianna Mazza, Alexia Koukopoulos, Georgios D. Kotzalidis, Lorenzo Moccia, Alessio Simonetti, Delfina Janiri, Marco Di Nicola, Gabriele Sani, Giovanni Camardese Geriatrics Switzerland, 2026 Background: Late-onset depression (LOD) represents a distinct clinical and biological phenotype emerging in the context of global population ageing. This study aims to synthesize current evidence on the epidemiology, risk factors, mechanistic pathways, and therapeutic approaches of LOD, integrating biological, psychological, and social dimensions. Methods: This narrative review synthesizes recent evidence across epidemiology, clinical symptomatology, neurobiology, and treatment. Where conceptually appropriate or empirically overlapping, we incorporate findings from the broader late-life depression (LLD) literature. Results: LOD emerges (as a distinct clinical and biological entity in later life) as a clinically and biologically meaningful presentation of depression in later life, representing a minority of depressive cases. It is defined by prominent apathy, psychomotor slowing, and cognitive impairment, and is closely linked to frailty, medical comorbidity, and heightened dementia risk. Pathophysiological mechanisms converge on vascular, inflammatory, oxidative, and neuroplasticity pathways, while psychosocial adversity further shapes onset and course. Treatment prioritizes efficacy and tolerability amid multiple morbidity; SSRIs and SNRIs are first-line, with pro-dopaminergic or dual-action agents addressing anhedonia and apathy, and neuromodulation or augmentation strategies reserved for resistance. Integrative approaches combining pharmacotherapy, psychotherapy, and lifestyle interventions are essential to optimize outcomes in aging populations. Conclusions: Late-onset depression (is a distinct, biologically and psychosocially driven disorder) represents a biologically and psychosocially enriched subtype in its own within the spectrum of late-life depression, requiring integrated, personalized care. Addressing neurovascular mechanisms, psychosocial adversity, and prevention through coordinated geriatric and psychiatric strategies may improve outcomes in aging populations.
Affective illness onset in women during the pre-, peri-, and post-menopausal phases Alexia Koukopoulos, Leonardo Tondo, Gabriele Sani, Delfina Janiri, Lavinia De Chiara, Ross J. Baldessarini Nordic Journal of Psychiatry, 2026 BACKGROUND: Many reports associate particular phases of the human reproductive cycle with psychiatric symptoms including depression, although details of associations of morbidity of depressive, bipolar, and anxiety disorders with pre-, peri-, and post-menopausal phases require further clarification. This naturalistic study evaluated the timing of onset and morbidity of mood and anxiety disorders in women during these menopausal phases. METHODS: = 928) with a primary diagnosis of BD type I or II (BD1 or BD2), major depressive disorder (MDD) or an anxiety disorder were clinically evaluated after menopause to determine the onset of affective illness during the pre, peri-, or post-menopausal phases. Psychometric scales were used to assess affective illness and multivariable regression modeling was used to compare menopausal phases. RESULTS: Many descriptive and clinical measures differed significantly with illnesses starting in the three menstrual phases. Women with onset of affective illness in the perimenopause phase spent 1.33 more time ill than those starting in the premenopausal phase and 1.46 more time ill than women with postmenopausal onset, with corresponding differences in illness episodes/year as well as suicidal risks. CONCLUSIONS: Study findings are consistent with the view that onset in the peri-menopausal phase may be associated with an excess of affective morbidity in both MDD and BD and that the post-menopausal phase may involve less morbidity.
Pain and Suicide Behavior in Cancer Patients: Implications for Personalized Treatment—A Systematic Review Alessio Simonetti, Davide Tripaldella, Francesca Bardi, Mario Pinto, Romina Caso, Gianmarco Stella, Leonardo Monacelli, Giovanni Camardese, Antonio Maria D’Onofrio, Silvia Montanari, Delfina Janiri, Gabriele Sani Journal of Personalized Medicine, 2026 Objective: Pain is among the most common and debilitating symptoms experienced by oncology patients and has been associated with adverse mental health outcomes, including depression and suicide. Nevertheless, the relationship between pain and suicide in oncology populations remains insufficiently characterized. A clearer understanding of this interplay is essential to guide personalized approaches aimed at reducing cancer-related burden and improving quality of life. Methods: We searched PubMed and PsycInfo without imposing limits regarding publication date using pain* AND (suicid* OR “self-harm” OR “self-injurious behavior” OR “self-inflicted injury” or “self-killing”) AND (cancer* OR oncolog* OR tumor* OR neoplasm* OR metasta*). A total of 832 articles were identified, and 15 of them were included in our review. Results: Inadequately managed pain in cancer patients is associated with a significantly elevated risk of suicidal ideation. This association is further exacerbated in individuals presenting with depressive symptoms, advanced-stage disease, or limited access to timely psychological support. These factors may interact synergistically, intensifying the emotional and cognitive burden of pain, thereby increasing vulnerability in cancer patients. Conclusions: Cancer-related pain should be conceptualized as a highly variable indicator of psychological vulnerability. Factors influencing this variability include cancer type and severity, as well as the presence of past psychopathology. These findings support the need for a personalized medicine approach, whereby pain management and psychosocial interventions are tailored to patient-specific factors such as disease stage, psychological comorbidity, and access to supportive care.
Real-World Use, Effectiveness and Tolerability of Antidepressant Treatment in Oncology Patients Alessio Simonetti, Flavia Grisoni, Antonio Restaino, Claudia Calderoni, Giovanni Camardese, Antonio Maria Donofrio, Alexia Koukopoulos, Silvia Montanari, Delfina Janiri, Gabriele Sani Psycho Oncology, 2025 Background Depression significantly impacts quality of life and prognosis in subjects with cancer. Despite the evidence supporting the role of pharmacotherapy, real‐world data on the effectiveness and tolerability of different antidepressant classes in cancer populations remain limited. Objective To assess the effectiveness and tolerability of antidepressant classes and individual agents in oncology patients with major depressive disorder (MDD), and to investigate antidepressant prescription trends. Methods This 6‐month retrospective observational study was conducted in 170 oncology outpatients with MDD. Patients received monotherapy with tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), or a multimodal antidepressant class including only vortioxetine. Psychiatric symptoms were evaluated at baseline and after 1 and 6 months. Evaluation included rates of response, remission and changes in rating scales assessing depression, anxiety, suicidality, and agitation. Results All antidepressant classes showed comparable effectiveness and capability of reducing depression, anxiety, and suicidal ideation over time. Vortioxetine showed a favorable tolerability profile, with no reported adverse effects, whereas SSRIs and SNRIs had higher dropout rates due to side effects. SSRIs were the most prescribed class, followed by multimodal agents. Vortioxetine was the most frequently prescribed individual antidepressant, particularly among patients undergoing chemotherapy. Limitations The small sample size and the lack of stratification by cancer type limit the generalizability of the results. Conclusion Antidepressants were equally effective in treating depression among cancer patients. Vortioxetine emerged as a well‐tolerated and preferred option for chemotherapy patients. These findings emphasize the importance of tolerability and drug‐interaction profiles in oncology care.
Dopamine Partial Agonists in Pregnancy and Lactation: A Systematic Review Alexia Koukopoulos, Delfina Janiri, Miriam Milintenda, Sara Barbonetti, Georgios D. Kotzalidis, Tommaso Callovini, Lorenzo Moccia, Silvia Montanari, Marianna Mazza, Lucio Rinaldi, Alessio Simonetti, Mario Pinto, Giovanni Camardese, Gabriele Sani Pharmaceuticals, 2025
Pharmacological Interventions for Negative Symptoms in Schizophrenia: A Systematic Review of Randomised Control Trials Lorenzo Moccia, Francesca Bardi, Maria Benedetta Anesini, Sara Barbonetti, Georgios D. Kotzalidis, Sara Rossi, Romina Caso, Flavia Grisoni, Giuseppe Mandracchia, Stella Margoni, Tommaso Callovini, Delfina Janiri, Marianna Mazza, Alessio Simonetti, Silvia Montanari, Gianna Autullo, Giovanni Camardese, Maria Pepe, Marco Di Nicola, Vassilij Di Giorgio, Fabio Conti, Gabriele Sani, and Biomedicines, 2025
Psychiatric vulnerability in children growing up with a parent with cancer–a systematic review Silvia Montanari, Alexia Koukopoulos, Maria Benedetta Anesini, Francesca Bardi, Georgios D. Kotzalidis, Gianna Autullo, Elisa Marconi, Federica Moriconi, Daniela Pia Rosaria Chieffo, Giovanni Camardese, Gabriele Sani, Alessio Simonetti, Delfina Janiri International Review of Psychiatry, 2025
Psychological Sequelae of Dog Bites in Children: A Review Laura Monti, Georgios D. Kotzalidis, Valentina Arcangeli, Camilla Brozzi, Rossella Iacovino, Cristina Giansanti, Daniela Belella, Elisa Marconi, Silvia Maria Pulitanò, Marianna Mazza, Giuseppe Marano, Giorgio Conti, Delfina Janiri, Gabriele Sani, Daniela Pia Rosaria Chieffo Children, 2024
Obstetric Outcomes in Women on Lithium: A Systematic Review and Meta-Analysis Tommaso Callovini, Silvia Montanari, Francesca Bardi, Sara Barbonetti, Sara Rossi, Romina Caso, Giuseppe Mandracchia, Stella Margoni, Andrea Brugnami, Marco Paolini, Giovanni Manfredi, Luca Lo Giudice, Daniele Segatori, Andrea Zanzarri, Luca Onori, Claudia Calderoni, Elisabetta Benini, Giuseppe Marano, Marco Massetti, Federica Fiaschè, Federica Di Segni, Delfina Janiri, Alessio Simonetti, Lorenzo Moccia, Flavia Grisoni, Sara Ruggiero, Giovanni Bartolucci, Marco Biscosi, Ottavia Marianna Ferrara, Evelina Bernardi, Leonardo Monacelli, Alessandro Michele Giannico, Domenico De Berardis, Giulia Battisti, Michele Ciliberto, Caterina Brisi, Francesco Maria Lisci, Antonio Maria D’Onofrio, Antonio Restaino, Luca Di Benedetto, Maria Benedetta Anesini, Gianluca Boggio, Elettra Specogna, Arianna Crupi, Emanuela De Chiara, Emanuele Caroppo, Valentina Ieritano, Laura Monti, Daniela Pia Rosaria Chieffo, Lucio Rinaldi, Giovanni Camardese, Ilaria Cuomo, Roberto Brugnoli, Georgios D. Kotzalidis, Gabriele Sani, Marianna Mazza Journal of Clinical Medicine, 2024
Is Antipsychotic Drug Use During Pregnancy Associated with Increased Malformation Rates and Worsening of Maternal and Infant Outcomes? A Systematic Review Gabriele Sani, Tommaso Callovini, Ottavia Marianna Ferrara, Daniele Segatori, Stella Margoni, Alessio Simonetti, Francesco Maria Lisci, Giuseppe Marano, Alessia Fischetti, Georgios D. Kotzalidis, Federica Di Segni, Federica Fiaschè, Delfina Janiri, Lorenzo Moccia, Giovanni Manfredi, Alessandro Alcibiade, Caterina Brisi, Flavia Grisoni, Gianmarco Stella, Evelina Bernardi, Andrea Brugnami, Michele Ciliberto, Maria Chiara Spera, Romina Caso, Sara Rossi, Gianluca Boggio, Giulia Mastroeni, Francesca Abate, Eliana Conte, Anna Quintano, Lavinia De Chiara, Laura Monti, Giovanni Camardese, Lucio Rinaldi, Alexia E. Koukopoulos, Daniela Pia Rosaria Chieffo, Gloria Angeletti, Marianna Mazza Current Neuropharmacology, 2024
Malnutrition in COVID-19 survivors: prevalence and risk factors Matteo Tosato, Riccardo Calvani, Francesca Ciciarello, Vincenzo Galluzzo, Anna Maria Martone, Maria Beatrice Zazzara, Cristina Pais, Giulia Savera, Maria Camprubi Robles, Maria Ramirez, Francesco Landi, Francesco Landi, Elisa Gremese, Roberto Bernabei, Massimo Fantoni, Antonio Gasbarrini, Matteo Tosato, Carlo Romano Settanni, Serena Porcari, Francesca Benvenuto, Giulia Bramato, Vincenzo Brandi, Angelo Carfì, Francesca Ciciarello, Maria Rita Lo Monaco, Anna Maria Martone, Emanuele Marzetti, Carmen Napolitano, Vincenzo Galluzzo, Francesco Pagano, Cristina Pais, Sara Rocchi, Elisabetta Rota, Andrea Salerno, Matteo Tosato, Marcello Tritto, Riccardo Calvani, Maria Beatrice Zazzara, Lucio Catalano, Anna Picca, Giulia Savera, Mariaelena D’Elia, Damiano Biscotti, Roberto Cauda, Rita Murri, Antonella Cingolani, Giulio Ventura, Eleonora Taddei, Davide Moschese, Arturo Ciccullo, Massimo Fantoni, Leonardo Stella, Giovanni Addolorato, Francesco Franceschi, Gertrude Mingrone, Maria Assunta Zocco, Maurizio Sanguinetti, Paola Cattani, Simona Marchetti, Brunella Posteraro, Michela Sali, Alessandra Bizzarro, Alessandra Lauria, Stanislao Rizzo, Maria Cristina Savastano, Gloria Gambini, Grazia Maria Cozzupoli, Carola Culiersi, Giulio Cesare Passali, Gaetano Paludetti, Jacopo Galli, Fabrizio Crudo, Giovanni Di Cintio, Ylenia Longobardi, Laura Tricarico, Mariaconsiglia Santantonio, Tiziana Di Cesare, Mariateresa Guarino, Marco Corbò, Stefano Settimi, Dario Mele, Francesca Brigato, Danilo Buonsenso, Piero Valentini, Dario Sinatti, Gabriella De Rose, Luca Richeldi, Francesco Lombardi, Angelo Calabrese, Francesco Varone, Paolo Maria Leone, Matteo Siciliano, Giuseppe Maria Corbo, Giuliano Montemurro, Mariarosaria Calvello, Enrica Intini, Jacopo Simonetti, Giuliana Pasciuto, Veronica Adiletta, Carmelo Sofia, Maria Angela Licata, Gabriele Sani, Delfina Janiri, Alessio Simonetti, Marco Modica, Montanari Silvia, Antonello Catinari, Beatrice Terenzi, Luigi Natale, Anna Rita Larici, Riccardo Marano, Tommaso Pirronti, Amato Infante, Annamaria Paglionico, Luca Petricca, Barbara Tolusso, Stefano Alivernini, Clara Di Mario, Angelo Santoliquido, Luca Santoro, Antonio Nesci, Angela Di Giorgio, Alessia D’Alessandro, and Aging Clinical and Experimental Research, 2023
Association of Delirium and Depression with Respiratory and Outcome Measures in COVID-19 Inpatients Alessio Simonetti, Cristina Pais, Vezio Savoia, Maria Camilla Cipriani, Matteo Tosato, Delfina Janiri, Evelina Bernardi, Ottavia Marianna Ferrara, Stella Margoni, Georgios D. Kotzalidis, Daniela Chieffo, Massimo Fantoni, Rosa Liperoti, Francesco Landi, Roberto Bernabei, Gabriele Sani Journal of Personalized Medicine, 2023
Depressive Symptoms during Pregnancy: Prevalence and Correlates with Affective Temperaments and Psychosocial Factors Marianna Mazza, Carla Avallone, Georgios Demetrios Kotzalidis, Giuseppe Marano, Lorenzo Moccia, Anna Maria Serio, Marta Balocchi, Ilenia Sessa, Delfina Janiri, Ilaria De Luca, Caterina Brisi, Maria Chiara Spera, Laura Monti, Angela Gonsalez del Castillo, Gloria Angeletti, Daniela Chieffo, Lucio Rinaldi, Luigi Janiri, Antonio Lanzone, Giovanni Scambia, Eugenio Maria Mercuri, Gabriele Sani Journal of Personalized Medicine, 2023
COVID-19 and New-Onset Psychosis: A Comprehensive Review Lorenzo Moccia, Georgios D. Kotzalidis, Giovanni Bartolucci, Sara Ruggiero, Laura Monti, Marco Biscosi, Beatrice Terenzi, Ottavia M. Ferrara, Marianna Mazza, Marco Di Nicola, Delfina Janiri, Alessio Simonetti, Emanuele Caroppo, Luigi Janiri, Gabriele Sani Journal of Personalized Medicine, 2023
Post-COVID-19 Psychiatric Symptoms in the Elderly: The Role of Gender and Resilience Delfina Janiri, Matteo Tosato, Alessio Simonetti, Silvia Montanari, Beatrice Terenzi, Antonello Catinari, Lorenzo De Mori, Gaspare Filippo Ferrajoli, Georgios D. Kotzalidis, Francesco Landi, Roberto Bernabei, Gabriele Sani Journal of Personalized Medicine, 2022
COVID-19 atypical Parsonage-Turner syndrome: a case report Maria Beatrice Zazzara, Anna Modoni, Alessandra Bizzarro, Alessandra Lauria, Francesca Ciciarello, Cristina Pais, Vincenzo Galluzzo, Francesco Landi, Matteo Tostato, Francesco Landi, Elisa Gremese, Roberto Bernabei, Massimo Fantoni, Antonio Gasbarrini, Carlo Romano Settanni, Serena Porcari, Francesca Benvenuto, Giulia Bramato, Vincenzo Brandi, Angelo Carfì, Francesca Ciciarello, Maria Rita Lo Monaco, Anna Maria Martone, Emanuele Marzetti, Carmen Napolitano, Vincenzo Galluzzo, Francesco Pagano, Cristina Pais, Sara Rocchi, Elisabetta Rota, Andrea Salerno, Matteo Tosato, Marcello Tritto, Riccardo Calvani, Maria Beatrice Zazzara, Lucio Catalano, Anna Picca, Giulia Savera, Roberto Cauda, Rita Murri, Antonella Cingolani, Giulio Ventura, Eleonora Taddei, Davide Moschese, Arturo Ciccullo, Massimo Fantoni, Leonardo Stella, Giovanni Addolorato, Francesco Franceschi, Gertrude Mingrone, Maria Assunta Zocco, Maurizio Sanguinetti, Paola Cattani, Simona Marchetti, Brunella Posteraro, Michela Sali, Alessandra Bizzarro, Alessandra Lauria, Stanislao Rizzo, Maria Cristina Savastano, Gloria Gambini, Maria Grazia Cozzupoli, Carola Culiersi, Giulio Cesare Passali, Gaetano Paludetti, Jacopo Galli, Fabrizio Crudo, Giovanni Di Cintio, Ylenia Longobardi, Laura Tricarico, Mariaconsiglia Santantonio, Tiziana Di Cesare, Mariateresa Guarino, Marco Corbò, Stefano Settimi, Dario Mele, Francesca Brigato, Danilo Buonsenso, Piero Valentini, Dario Sinatti, Gabriella De Rose, Luca Richeldi, Francesco Lombardi, Angelo Calabrese, Francesco Varone, Paolo Maria Leone, Matteo Siciliano, Giuseppe Maria Corbo, Giuliano Montemurro, Mariarosaria Calvello, Enrica Intini, Jacopo Simonetti, Giuliana Pasciuto, Veronica Adiletta, Carmelo Sofia, Maria Angela Licata, Gabriele Sani, Delfina Janiri, Alessio Simonetti, Marco Modica, Silvia Montanari, Antonello Catinari, Beatrice Terenzi, Luigi Natale, Anna Rita Larici, Riccardo Marano, Tommaso Pirronti, Amato Infante, Annamaria Paglionico, Luca Petricca, Barbara Tolusso, Stefano Alivernini, Clara Di Mario, Angelo Santoliquido, Luca Santoro, Antonio Nesci, Angela Di Giorgio, and BMC Neurology, 2022
Depressive Symptoms in Expecting Fathers: Is Paternal Perinatal Depression a Valid Concept? A Systematic Review of Evidence Marianna Mazza, Georgios D. Kotzalidis, Carla Avallone, Marta Balocchi, Ilenia Sessa, Ilaria De Luca, Daniele Hirsch, Alessio Simonetti, Delfina Janiri, Emanuela Loi, Giuseppe Marano, Gabriella Albano, Vittorio Fasulo, Stefania Borghi, Angela Gonsalez del Castillo, Anna Maria Serio, Laura Monti, Daniela Chieffo, Gloria Angeletti, Luigi Janiri, Gabriele Sani Journal of Personalized Medicine, 2022
Fatigue in Covid-19 survivors: The potential impact of a nutritional supplement on muscle strength and function Vincenzo Galluzzo, Maria Beatrice Zazzara, Francesca Ciciarello, Giulia Savera, Cristina Pais, Riccardo Calvani, Anna Picca, Emanuele Marzetti, Francesco Landi, Matteo Tosato, Steering Committee, Francesco Landi, Elisa Gremese, Coordination, Roberto Bernabei, Massimo Fantoni, Antonio Gasbarrini, Field investigators, Gastroenterology team, Serena Porcari, Carlo Romano Settanni, Geriatric team, Francesca Benvenuto, Giulia Bramato, Vincenzo Brandi, Angelo Carfì, Francesca Ciciarello, Sofia Fabrizi, Vincenzo Galluzzo, Maria Rita Lo Monaco, Anna Maria Martone, Emanuele Marzetti, Carmen Napolitano, Francesco Cosimo Pagano, Cristina Pais, Sara Rocchi, Elisabetta Rota, Andrea Salerno, Matteo Tosato, Marcello Tritto, Maria Beatrice Zazzara, Riccardo Calvani, Lucio Catalano, Anna Picca, Giulia Savera, Francesco Paolo Damiano, Alessandra Rocconi, Alessandro Galliani, Giovanni Spaziani, Salvatore Tupputi, Camilla Cocchi, Flavia Pirone, Federica D'Ignazio, Stefano Cacciatore, Infectious disease team, Roberto Cauda, Enrica Tamburrini, A. Borghetti, Simona Di Gianbenedetto, Rita Murri, Antonella Cingolani, Giulio Ventura, E. Taddei, D. Moschese, A. Ciccullo, A. Dusina, Internal Medicine team, Leonardo Stella, Giovanni Addolorato, Francesco Franceschi, Gertrude Mingrone, M.A. Zocco, Microbiology team, Maurizio Sanguinetti, Paola Cattani, Simona Marchetti, Brunella Posteraro, M. Sali, Neurology team, Alessandra Bizzarro, Alessandra Lauria, Ophthalmology team, Stanislao Rizzo, Maria Cristina Savastano, G. Gambini, G.M. Cozzupoli, C. Culiersi, Otolaryngology team, Giulio Cesare Passali, Gaetano Paludetti, Jacopo Galli, F. Crudo, G. Di Cintio, Y. Longobardi, L. Tricarico, M. Santantonio, Pediatric team, Danilo Buonsenso, P. Valentini, D. Pata, D. Sinatti, C. De Rose, Pneumology team, Luca Richeldi, Francesco Lombardi, A. Calabrese, Paolo Maria Leone, Maria Rosaria Calvello, Enrica Intini, Giuliano Montemurro, Psychiatric team, Gabriele Sani, Delfina Janiri, Alessio Simonetti, G. Giuseppin, M. Molinaro, M. odica, Radiology team, Luigi Natale, Anna Rita Larici, Riccardo Marano, Rheumatology team, Annamaria Paglionico, Luca Petricca, Luca Gigante, G. Natalello, A.L. Fedele, M.M. Lizzio, B. Tolusso, Clara Di Mario, S. Alivernini, Vascular team, Angelo Santoliquido, Luca Santoro, Angela Di Giorgio, Antonio Nesci, V. Popolla Clinical Nutrition Espen, 2022
Lifestyle Changes and Psychological Well-Being in Older Adults During COVID-19 Pandemic Matteo Tosato, Francesca Ciciarello, Maria Beatrice Zazzara, Delfina Janiri, Cristina Pais, Stefano Cacciatore, Rossella Montenero, Maria Sandrina Leone, Enea Chisci, Anna Picca, Vincenzo Galluzzo, Hélio José Coelho-Junior, Riccardo Calvani, Emanuele Marzetti, Francesco Landi Clinics in Geriatric Medicine, 2022
Neuropsychological Measures of Long COVID-19 Fog in Older Subjects Alessandra Lauria, Angelo Carfi, Francesca Benvenuto, Giulia Bramato, Francesca Ciciarello, Sara Rocchi, Elisabetta Rota, Andrea Salerno, Leonardo Stella, Marcello Tritto, Antonella Di Paola, Cristina Pais, Matteo Tosato, Delfina Janiri, Gabriele Sani, Francesco Cosimo Pagano, Massimo Fantoni, Roberto Bernabei, Francesco Landi, Alessandra Bizzarro Clinics in Geriatric Medicine, 2022
Psychosis in women: Time for personalized treatment Marianna Mazza, Emanuele Caroppo, Domenico De Berardis, Giuseppe Marano, Carla Avallone, Georgios D. Kotzalidis, Delfina Janiri, Lorenzo Moccia, Alessio Simonetti, Eliana Conte, Giovanni Martinotti, Luigi Janiri, Gabriele Sani Journal of Personalized Medicine, 2021
Residual respiratory impairment after COVID-19 pneumonia Francesco Lombardi, Angelo Calabrese, Bruno Iovene, Chiara Pierandrei, Marialessia Lerede, Francesco Varone, Luca Richeldi, Giacomo Sgalla, Francesco Landi, Elisa Gremese, Roberto Bernabei, Massimo Fantoni, Antonio Gasbarrini, Carlo Romano Settanni, Francesca Benvenuto, Giulia Bramato, Angelo Carfì, Francesca Ciciarello, Maria Rita Lo Monaco, Anna Maria Martone, Emanuele Marzetti, Carmen Napolitano, Francesco Pagano, Sara Rocchi, Elisabetta Rota, Andrea Salerno, Matteo Tosato, Marcello Tritto, Riccardo Calvani, Lucio Catalano, Anna Picca, Giulia Savera, Enrica Tamburrini, Alberto Borghetti, Simona Di Gianbenedetto, Rita Murri, Antonella Cingolani, Giulio Ventura, Eleonora Taddei, Davide Moschese, Arturo Ciccullo, Leonardo Stella, Giovanni Addolorato, Francesco Franceschi, Gertrude Mingrone, Maria Assunta Zocco, Mauirizio Sanguinetti, Paola Cattani, Simona Marchetti, Alessandro Bizzarro, Alessandra Lauria, Stanislao Rizzo, Maria Cristina Savastano, Gloria Gambini, Maria Grazia Cozzupoli, Carola Culiersi, Giulio Cesare Passali, Gaetano Paludetti, Jacopo Galli, Fabrizio Crudo, Giovanni Di Cintio, Ylenia Longobardi, Laura Tricarico, Mariaconsiglia Santantonio, Danilo Buonsenso, Piero Valentini, Davide Pata, Davide Sinatti, Cristina. De Rose, Luca Richeldi, Francesco Lombardi, Aangelo Calabrese, Gabriele Sani, Delfina Janiri, Giulia Giuseppin, Marzia Molinaro, Marco Modica, Luigi Natale, Anna Rita Larici, Riccardo Marano, Annamaria Paglionico, Luca Petricca, Laura Gigante, Gerlando Natalello, Anna Laura. Fedele, Marco Maria Lizzio, Angelo Santoliquido, Luca Santoro, Antonio Nesci, Valentina Popolla, and BMC Pulmonary Medicine, 2021
Retinal capillary involvement in early post-COVID-19 patients: a healthy controlled study Maria Cristina Savastano, Gloria Gambini, Grazia Maria Cozzupoli, Emanuele Crincoli, Alfonso Savastano, Umberto De Vico, Carola Culiersi, Benedetto Falsini, Francesco Martelli, Angelo Maria Minnella, Francesco Landi, Francesco Cosimo Pagano, Stanislao Rizzo, and Graefe S Archive for Clinical and Experimental Ophthalmology, 2021
Post-COVID-19 global health strategies: the need for an interdisciplinary approach F. E. R. M. A. C. R. F. G. A. F. M. R. A. M. E. C. F. Landi Gremese Bernabei Fantoni Gasbarrini Settanni, F. Landi, E. Gremese, R. Bernabei, M. Fantoni, A. Gasbarrini, C. Settanni, F. Benvenuto, G. Bramato, A. Carfì, F. Ciciarello, M. R. Lo Monaco, A. M. Martone, E. Marzetti, C. Napolitano, F. Pagano, S. Rocchi, E. Rota, A. Salerno, M. Tosato, M. Tritto, R. Calvani, L. Catalano, A. Picca, G. Savera, E. Tamburrini, A. Borghetti, S. Di Gianbenedetto, R. Murri, A. Cingolani, G. Ventura, E. Taddei, D. Moschese, A. Ciccullo, L. Stella, G. Addolorato, F. Franceschi, G. Mingrone, M. A. Zocco, M. Sanguinetti, P. Cattani, S. Marchetti, A. Bizzarro, A. Lauria, S. Rizzo, M. Savastano, G. Gambini, G. M. Cozzupoli, C. Culiersi, G. Passali, G. Paludetti, J. Galli, F. Crudo, G. Di Cintio, Y. Longobardi, L. Tricarico, M. Santantonio, D. Buonsenso, P. Valentini, D. Pata, D. Sinatti, C. De Rose, L. Richeldi, F. Lombardi, A. Calabrese, G. Sani, D. Janiri, G. Giuseppin, M. Molinaro, M. Modica, L. Natale, A. R. Larici, R. Marano, A. Paglionico, L. Petricca, L. Gigante, G. Natalello, A. L. Fedele, M. M. Lizzio, A. Santoliquido, L. Santoro, A. Nesci, V. Popolla Aging Clinical and Experimental Research, 2020
Perinatal Mixed Affective State: Wherefore Art Thou? Alexia Emilia Koukopoulos, Gloria Angeletti, Gabriele Sani, Delfina Janiri, Giovanni Manfredi, Georgios D. Kotzalidis, Lavinia De Chiara Psychiatric Clinics of North America, 2020
Are 5-HT3 antagonists effective in obsessive-compulsive disorder? A systematic review of literature Daniele Serata, Georgios D. Kotzalidis, Chiara Rapinesi, Delfina Janiri, Simone Di Pietro, Gemma Callovini, Daria Piacentino, Carlotta Gasperoni, Roberto Brugnoli, Vittoria Rachele Ferri, Nicoletta Girardi, Roberto Tatarelli, Stefano Ferracuti, Gloria Angeletti, Paolo Girardi, Antonio Del Casale Human Psychopharmacology, 2015
Mitochondrial myopathy and comorbid major depressive disorder: Effectiveness of dTMS on gait and mood symptoms Chiara Rapinesi, Delfina Janiri, Georgios D. Kotzalidis, Daniele Serata, Antonio Del Casale, Paola Scatena, Claudia Dacquino, Giovanna Gentile, Giovanni Manfredi, Emanuela Danese, Ruggero Nessim Raccah, Roberto Brugnoli, Gemma Callovini, Vittoria Rachele Ferri, Stefano Ferracuti, Abraham Zangen, Maurizio Simmaco, Gloria Angeletti, Paolo Girardi General Hospital Psychiatry, 2015
Low-dose acetazolamide in the treatment of premenstrual dysphoric disorder: A case series Gabriele Sani, Georgios D. Kotzalidis, Isabella Panaccione, Alessio Simonetti, Lavinia De Chiara, Antonio Del Casale, Elisa Ambrosi, Flavia Napoletano, Delfina Janiri, Emanuela Danese, Nicoletta Girardi, Chiara Rapinesi, Daniele Serata, Giovanni Manfredi, Alexia E. Koukopoulos, Gloria Angeletti, Ferdinando Nicoletti, Paolo Girardi Psychiatry Investigation, 2014
Alcohol and suicidality: Could Deep Transcranial Magnetic Stimulation (DTMS) be a possible treatment? Psychiatria Danubina, 2014
Neurodevelopment in schizophrenia: The role of the wnt pathways Isabella Panaccione, Flavia Napoletano, Alberto Forte, Giorgio Kotzalidis, Antonio Casale, Chiara Rapinesi, Chiara Brugnoli, Daniele Serata, Federica Caccia, Ilaria Cuomo, Elisa Ambrosi, Alessio Simonetti, Valeria Savoja, Lavinia Chiara, Emanuela Danese, Giovanni Manfredi, Delfina Janiri, Marta Motolese, Ferdinando Nicoletti, Paolo Girardi, Gabriele Sani Current Neuropharmacology, 2013
Intramuscular aripiprazole in the acute management of psychomotor agitation Sergio De Filippis, Ilaria Cuomo, Luana Lionetto, Delfina Janiri, Maurizio Simmaco, Matteo Caloro, Simone De Persis, Gioia Piazzi, Alessio Simonetti, C Ludovica Telesforo, Antonio Sciarretta, Federica Caccia, Giovanna Gentile, Georgios D. Kotzalidis, Paolo Girardi Pharmacotherapy, 2013
Olanzapine in manic/mixed patients with or without substance abuse Rivista Di Psichiatria, 2013
