Mario Santini
@unicampania.it
Universita Vanvitelli
Scopus Publications
- Artificial Intelligence in Lung Cancer Diagnosis: “SYNERGY-NET” in Campania FESR-POR (European Fund of Regional Development—Regional Operative Program) Research Project
Domenico Parmeggiani, Alfonso Fiorelli, Giancarlo Moccia, Pasquale Luongo, Vittorio d’Orlando, Pasquale Sperlongano, Francesco Miele, Francesco Torelli, Stefano Marrone, Michela Gravina, Carlo Sansone, Ruggiero Bollino, Paola Bassi, Antonella Sciarra, Mario Santini, Paola Della Monica, Federica Colapietra, Marina Di Domenico, Ludovico Docimo, Massimo Agresti
Smart Innovation Systems and Technologies, 2024 - The Prediction of Fissure Integrity by Quantitative Computed Tomography Analysis
Antonio Noro, Giovanni Natale, Gaetana Messina, Beatrice Leonardi, Anna Rainone, Mario Santini, Alfonso Fiorelli
Thoracic and Cardiovascular Surgeon, 2023
Background Incomplete interlobar fissure may increase the difficulty of thoracoscopic lobectomy. Herein, we compared the accuracy of visual versus quantitative analysis to predict fissure integrity in lung cancer patients undergoing thoracoscopic lobectomy and evaluated the effects of fissure integrity on surgical outcome. Methods This was a single-center retrospective study including consecutive patients undergoing VATS (video-assisted thoracoscopic surgery) lobectomy for lung cancer. The target interlobar fissures were classified as complete or incomplete by visual and quantitative analysis. Using the intraoperative finding as the reference method, the diagnostic accuracy of the two methods to define fissure completeness (dependent variable) was calculated and statistically compared. Yet, we evaluated differences in postoperative outcomes between patients with complete and incomplete fissure integrity. Results A total of 93 patients were included in the study; 33/93 (36%) presented complete fissure. Visual and quantitative analyses correctly identified complete fissure in 19/33 (57%) and 29/33 (88%) patients, respectively, and incomplete fissure in 56/60 (93%) and 58/60 (96%) patients, respectively. Quantitative analysis had better diagnostic accuracy than visual analysis (81 vs. 93%; p = 0.01). Patients with incomplete fissure compared with those with complete fissure had a higher conversion rate (6 vs. 13%; p = 0.43), higher persistent air leak rate (0/33 vs. 14/60; p = 0.03), and longer hospitalization (12.6 ± 3.8 vs. 7.1 ± 2.4 days; p = 0.01). Conclusions Quantitative analysis accurately predicted the fissures' integrity; it may be useful for selecting suitable cases for thoracoscopic lobectomy especially for surgeons with limited minimally invasive experience. - Bleeding during Learning Curve of Thoracoscopic Lobectomy: CUSUM Analysis Results
Alfonso Fiorelli, Roberto Cascone, Annalisa Carlucci, Giovanni Natale, Antonio Noro, Mary Bove, Mario Santini
Thoracic and Cardiovascular Surgeon, 2023
Background The management of intraoperative bleeding during thoracoscopic lobectomy is challenging, especially for non-experienced surgeons. We evaluated intraoperative bleeding in relation to learning curve of thoracoscopic lobectomy, the strategies to face it, the outcomes, and the target case number for gaining the technical proficiency. Methods This was a retrospective single center study including consecutive patients undergoing thoracoscopic lobectomy for lung cancer. Based on cumulative sum analysis, patients were divided into early and late experience groups, and the differences on surgical outcomes, with particular focus on vascular injury, were statistically compared. Results Eight-three patients were evaluated. Cumulative sum charts showed a decreasing of operative time, blood loss, and hospital stay after the 49th, the 43th, and the 39th case, respectively. Early (n = 49) compared with late experience group (n = 34) was associated with higher conversion rate (p = 0.08), longer operative time (p <0.0001), greater blood loss (p <0.0001), higher transfusion rate (p = 0.01), higher postoperative air leak rate (p = 0.02), longer chest tube stay (p <0.0001), and hospitalization (p <0.0001). Six patients (7%) had intraoperative bleeding during early phase of learning curve, successfully treated by thoracoscopy in four cases. Patients with vascular injury (n = 6) compared with control group (n = 77) presented a longer operative time (p = 0.003), greater blood loss (p = 0.0001), and higher transfusion rate (p = 0.001); no significant differences were found regarding postoperative morbidity (p = 0.57), length of chest tube stay (p = 0.07), and hospitalization (p = 0.07). Conclusion Technical proficiency was achieved after 50 procedures. All vascular injuries occurred in the early phase of learning curve; they were safely managed, without affecting surgical outcomes. - The use of fibrin glue for the endoscopic management of post-intubation tracheal lacerations: a case series
Beatrice Leonardi, Giovanni Natale, Gaetana Messina, Giorgia Opromolla, Rosa Mirra, Francesca Capasso, Vincenzo Di Filippo, Francesco Leone, Davide Gerardo Pica, Giuseppe Vicario, Cristiano Cesaro, Umberto Caterino, Giovanni Vicidomini, Mario Santini, Alfonso Fiorelli
Shanghai Chest, 2023
Video 1 The use of fibrin glue for the endoscopic management of post-intubation tracheal lacerations: a case series - Endoscopic treatment of solitary fibrous tumor of the trachea: a case report
Gaetana Messina, Mary Bove, Giovanni Natale, Alfonso Fiorelli, Giovanni Vicidomini, Mario Santini, Andrea Ronchi, Mario Pirozzi, Sergio Facchini, Fortunato Ciardiello, Morena Fasano
Translational Cancer Research, 2023
Background Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, generally arising in the visceral pleura. It rarely originates from other sites such as trachea, orbital cavities, nasal cavities, peritoneum, paranasal sinuses, meninges, salivary glands, thyroid gland, diaphragm, liver, pancreas, lung kidney, adrenal gland, mediastinum, spermatid cord, pericardium, urinary bladder, prostate, uterine cervix, testis, spinal cord, periosteum, skin, soft tissue and bone. Case Description We present a surgical case of a rare primary tracheal tumor. High resolution computed tomography (HRCT) scan of the chest showed a 5 mm hypodense lesion, located on the right lateral wall of the proximal third of trachea; however the tracheal lumen was normal. We performed a rigid bronchoscopy in order to remove the endotracheal tumor with palliative purposes only. For this reason, we did not perform a prior histologic examination. The lesion was easily removed with common biopsy forceps and with standard aspirator. The debulking of the tumor was achieved with the use of laser Nd-YAP, electrocautery was used also for hemostasis to prevent bleeding during the operation. Without complications during the endoscopic treatment, the procedure was well tolerated by the patient. The pathological diagnosis was SFT. Conclusions SFT located in the trachea can be endoscopically resceted. Endoscolical treatment is indicated for patients with poor clinical conditions (heart disease, respiratory failure) that are not elegible for surgical resection. - Endovascular Surgery of Descending Thoracic Aorta Involved in T4 Lung Tumor
Luigi Di Tommaso, Ettorino Di Tommaso, Raffaele Giordano, Emilio Mileo, Mario Santini, Emanuele Pilato, Gabriele Iannelli
Journal of Endovascular Therapy, 2023
Purpose: Surgical treatment of primary lung T4 tumors is controversial especially when the cancer invades the mediastinal structures or the descending thoracic aorta. Conventional surgical treatment is associated with a high perioperative mortality and morbidity rate. Thoracic EndoVascular Aortic Repair has emerged as a valid off-label alternative to conventional surgery. We aimed to assess perioperative and midterm aortic-related outcome of patients who have undergone aortic stent-graft implantation, followed by en bloc surgical treatment of the involved aorta and lung cancer resection. Materials and Methods: From July 2017 to May 2020, we treated 5 patients diagnosed with a T4 lung cancer by the involvement of the descending thoracic aorta. When only the descending thoracic aorta is involved, a 2-stage procedure was considered, with aortic stent-graft implantation performed before tumor resection. One-stage strategy, with stent-graft implantation carried out before thoracotomy, was preferred for patients with the involvement of cardiac and/or other vascular mediastinal structures. Results: The mean age was 58.4 ± 6.2 years. All patients were affected by non–small cell lung cancer. All 5 patients required a single stent-graft to completely cover the involved segment of aorta. Four patients underwent a 2-stage procedure. One patient, with the involvement of the left inferior pulmonary vein, required a 1-stage en bloc resection of the left lower lobe, aortic wall adventitia, left inferior pulmonary vein, and reconstruction of the left atrial wall. Primary procedural success was achieved in all. At follow-up, no patient developed aortic-related complications. One patient died 2 years after surgery, due to local recurrence of the tumor. Conclusion: T4 lung resection combined with aortic stent-graft implantation can be safely performed. Endovascular surgery, by avoiding the use of cardiopulmonary bypass, aortic cross-clamping, and graft replacement, can reduce significant morbidity and mortality rate. Postoperative and long-term outcome of these patients treated with endovascular surgery is mainly related to pulmonary disease, not to aortic treatment. - Ventilation challenge in rigid bronchoscopy: Laser tube as an alternative management in patients with lung cancer and central airway obstruction
Gaetana Messina, Mary Bove, Giovanni Natale, Vincenzo Di Filippo, Giorgia Opromolla, Eva Massimilla, Mauro Forte, Anna Rainone, Giuseppe Vicario, Beatrice Leonardi, Alfonso Fiorelli, Giovanni Vicidomini, Mario Santini, Mario Pirozzi, Marianna Caterino, Carminia Maria Della Corte, Fortunato Ciardiello, Morena Fasano
Thoracic Cancer, 2023
INTRODUCTION Central airway tumors involving the trachea and main-stem bronchi are a common cause of airway obstruction and a significant cause of mortality among the patients of thoracic diseases with respiratory failure. Debulking in rigid bronchoscopy is quick, safe, and effective. It can be complex and hard in patients with severe bronchial or tracheal obstruction and/or with intraluminal bleeding tumors because of inadequate distal airway control. We have used laser tube as a new technique of ventilation for severe central airway obstruction. MATERIALS AND METHODS Forty-six patients with severe airway obstruction undergoing rigid bronchoscopy from September 2020 to June 2022 at the Thoracic Surgery Department of the University L. Vanvitelli of Naples underwent placement of laser tube. RESULTS In all patients who underwent rigid bronchoscopy with the use of the laser tube, a reduction of obstruction of more than 50% was obtained and in all patients no hypoxia (saturation < 88%), nor hypercapnia, nor significant bleeding were reported. DISCUSSION The results of this study suggest that rigid bronchoscopic debulking with the use of laser tube is a safe and effective technique in the management of central airway obstruction. CONCLUSIONS The use of the laser tube allows the monitoring of gas exchange, which controls hypoxemia. Thanks to the double cuff put distally to the tracheal obstruction or in the contralateral bronchus to the obstructed one, the laser tube prevents the flooding of blood from debulking below the stenosis. Rigid bronchoscopy with laser tube will expand its use in the future. - Diagnosis of malignant pleural disease: Ultrasound as “a detective probe”
Gaetana Messina, Mary Bove, Giovanni Natale, Vincenzo Di Filippo, Giorgia Opromolla, Anna Rainone, Beatrice Leonardi, Mario Martone, Alfonso Fiorelli, Giovanni Vicidomini, Mario Santini, Andrea Ronchi, Eva Massimilla, Carminia Maria Della Corte, Mario Pirozzi, Marianna Caterino, Fortunato Ciardiello, Morena Fasano
Thoracic Cancer, 2023
BACKGROUND Malignant pleural mesothelioma (MPM) is an invasive, aggressive pleural tumor with a predominantly local spread. The objective of this study was to assess thoracic ultrasound (TUS) as an imaging modality with high sensitivity for the identification of malignant pleural involvement and in order to guide pleural biopsies. METHODS In this retrospective single-center study between January 2018 and June 2022, 51 consecutive patients with impassable circumferential pleural thickening underwent TUS at the Thoracic Surgery Unit of the Vanvitelli University of Naples. Pleural biopsies were performed, and then large and multiple samples were sent to the pathological anatomy for histological examination. RESULTS In all patients who underwent ultrasound examination, we chose the optimal point of entry to perform pleural biopsies and selected the areas of greater thickening without pleural effusion. No patient had any complications. No drainage tubes were placed after the pleural biopsies and no pneumothorax was present during the following days of hospitalization. The patients were discharged on the second postoperative day. CONCLUSION With TUS the precise pleural thickening localization, local infiltration, mass extent, its nature (solid, cystic or complex) and ultrasound features can be easily defined. Furthermore, ultrasound is more economical than computed tomography and avoids the risks associated with radiation. Thoracic ultrasound is an important component of the diagnostic procedure in detecting a safe entry site for biopsies of MPMs. - Combined minimally invasive para-esophageal hernia repair and lobectomy for lung cancer
Alfonso Fiorelli, Stefano Forte, Salvatore Tolone, Giovanni Natale, Mario Santini, Ludovico Docimo
Jtcvs Techniques, 2022
Central MessageCombined ipsilateral para-esophageal hernia repair and lobectomy prevented life-threatening complications such as intrathoracic gastric volvulus from the presence of hernia after lobectomy. Combined ipsilateral para-esophageal hernia repair and lobectomy prevented life-threatening complications such as intrathoracic gastric volvulus from the presence of hernia after lobectomy. Herein, we report a combined minimally invasive surgical approach to manage ipsilateral para-esophageal hernia, and lung cancer concurrently, to alleviate potentially detrimental complications from the presence of hernia after lobectomy. A 61-year-old morbidly obese woman (weight: 91 kg, body mass index: 41) with a history of arterial hypertension and chronic obstructive pulmonary disease (COPD) and with a known preexisting para-esophageal hernia was referred to our attention for management of early-stage lung adenocarcinoma of the left lower lobe (T1 cN0 M0) (Figure 1, A). No other lesions were found on whole body positron emission tomography scan. The patient complained only of occasional gastroesophageal reflux; for that her local gastroenterologist did not recommend surgical correction. After preoperative multidisciplinary assessment, the patient was scheduled for concomitant laparoscopic hernia repair and thoracoscopic lobectomy. The patient was intubated with a double-lumen tube and the para-esophageal hernia was repaired through a standard laparoscopic approach. The hernia containing the stomach was reduced, and the hernia sac was excised. The gastric lipoma and gastric vessels were resected using LigaSure (Medtronic) up to the left crura of the diaphragm. The hiatal hernia defect was closed with interrupted sutures, followed by a Dor fundoplication. Then, the patient was placed in a right lateral decubitus position and a standard triportal thoracoscopy with anterior access was performed. The pulmonary ligament was carefully resected from the hernia sac using a Harmonic device (Ethicon Endo-Surgery Inc), and the inferior pulmonary vein was isolated and mechanically resected. Then, the fissure between the S5 and S7 segment, the A6 artery branch, the basal pyramid artery, and the lower bronchus were sequentially stapled. After retrieval of the specimen, a radical lymphadenectomy completed the procedure, and 1 chest tube for drainage was left in the pleural cavity. Video 1 summarizes the procedure. Total operative duration was 235 minutes, with 100 minutes for hernia repair and 135 minutes for lobectomy. The total estimated blood loss was 270 mL and no intraoperative issues were found. Surgical pathology confirmed a pT1 cN0 M0 adenocarcinoma, with negative surgical margins. Postoperative course was unremarkable. Chest drainage was removed 3 days later, and the patient was discharged 5 days after the operation. At 1-month follow-up, a computed tomography scan (Figure 1, B) and barium swallow radiograph showed expansion of the remaining lobe without hernia recurrence. The patient did not have symptoms of reflux and was able to tolerate an oral diet. The patient was followed with computed tomography scan every 3 months for the first 2 years for lung cancer and with yearly esophagogram for hernia repair. The patient gave a written informed consent for this publication. Thoracoscopic lobectomy is the recommended approach for management of early-stage lung cancer in high-risk patients at present, due to incurring less surgical trauma compared with thoracotomy,1Paul S. Altorki N.K. Sheng S. Lee P.C. Harpole D.H. Onaitis M.W. et al.Thoracoscopic lobectomy is associated with lower morbidity than open lobectomy: a propensity-matched analysis from the STS database.J Thorac Cardiovasc Surg. 2010; 139: 366-378Abstract Full Text Full Text PDF PubMed Scopus (623) Google Scholar but a preexisting para-esophageal hernia may increase the risk of postoperative morbidity and mortality. Ten previous cases reported intrathoracic gastric volvulus resulting from pneumonectomy or lobectomy associated with a known preexisting hiatal hernia.2Parvathaneni S. Penafiel M. Garrett J. Toloza E. Fontaine J. Intrathoracic gastric volvulus complicating a robotic left upper lobectomy: a case report and review of literature.Int J Surg Case Rep. 2021; 78: 110-115Crossref PubMed Scopus (1) Google Scholar,3Toloza E. Straughan D. Hernandez J. Garrett J. Yamamoto M. Fakhry T. et al.Concurrent robotic-assisted laparoscopic paraesophageal hiatal hernia repair with Nissen fundoplication and robotic-assisted video-thoracoscopic pulmonary lobectomy for lung cancer: a case report.Cardiothorac Surg Cardiol Cardiothorac Surg. 2016; 149: A45Google Scholar Thus, we planned simultaneous surgical repair of the hernia and lobectomy. This approach possibly prevented complications from the presence of hernia after lobectomy while the concomitant lobectomy did not increase the risk of postoperative complications (ie, esophageal or stomach perforation or acute dysphagia) related to the hernia repair itself.4Botha A.J. Di Maggio F. Management of complications after paraesophageal hernia repair.Ann Laparosc Endosc Surg. 2021; 6: 38Crossref Google Scholar Potential additional advantages were that ipsilateral pleural or pericardial injuries related to the hernia repair were managed during lobectomy concurrently and that 1 dose of anesthesia, and 1 course of postanesthesia recovery were used for performing 2 different operations that would have required 2 staged procedures, with potential delay of lung cancer treatment. Toloza and colleagues3Toloza E. Straughan D. Hernandez J. Garrett J. Yamamoto M. Fakhry T. et al.Concurrent robotic-assisted laparoscopic paraesophageal hiatal hernia repair with Nissen fundoplication and robotic-assisted video-thoracoscopic pulmonary lobectomy for lung cancer: a case report.Cardiothorac Surg Cardiol Cardiothorac Surg. 2016; 149: A45Google Scholar reported the feasibility and safety of contralateral combined hiatal hernia repair with lobectomy for lung cancer, whereas in our case, for the first time, this procedure was performed on the same site. Technically, the presence of ipsilateral lung cancer did not interfere with the hernia repair, whereas the reposition of the stomach into the abdominal cavity facilitated thoracoscopic lobectomy (Figure 2) because the hernia, protruding into the posterior mediastinum, could complicate the identification and resection of the lower pulmonary vein, especially in a patient with obesity, as was seen here. During hernia repair, great care was made to prevent iatrogenic communications between diaphragm and pleural cavity given the presence of ipsilateral lung cancer. For that, our strategy was not indicated in presence of ipsilateral pleural effusion, due to the potential risk of abdominal contamination from pleural effusion, in case of diaphragm injury. A Dor rather than a Toupet fundoplication was performed because it was associated with a reduction of operative time (due to less dissection).5Tomasko J.M. Augustin T. Tran T.T. Haluck R.S. Rogers A.M. Lyn-Sue J.R. Quality of life comparing Dor and Toupet after Heller myotomy for achalasia.JSLS. 2014; 18e2014.00191Crossref PubMed Scopus (13) Google Scholar It could be valuable because lobectomy should be performed after hernia repair. eyJraWQiOiI4ZjUxYWNhY2IzYjhiNjNlNzFlYmIzYWFmYTU5NmZmYyIsImFsZyI6IlJTMjU2In0.eyJzdWIiOiIzNTNjZWU1NjkxZmFkZGUwOWYzYWFhZThkZDE2Y2M1NCIsImtpZCI6IjhmNTFhY2FjYjNiOGI2M2U3MWViYjNhYWZhNTk2ZmZjIiwiZXhwIjoxNjk1MDYzNDMyfQ.MNeGb9sohKa8slfqwgWOYyBjNnq4KUsDYKy0iiDdFii-9xCJ40qmyzxHN2kWzalSyYejDP2as_T0IFx0Lo8u0gzkNQX3MUcazU2pBE3M8KUEQTSFA5ViMppl0E9VF__lVMalnP0mF4db2E_zCuhpXxQmkCZJlblP_LtCgMYsQqX6FE5GGbnYaLbqHYbuebuYY1RJHKCcXeFWbzdsTZtWByDH2EdfI0SMuDCSp2B9_AVGKNgjBLQYSA1hJGu3wDSzsX9nH_m4PXRyxnKK218ORIsFruJU5mCoiBYhFfUGAJknNzWwR28GIYld2gKnoo7HI0KX0CtIr5F0ZKcAvmCdSg Download .mp4 (39.94 MB) Help with .mp4 files Video 1Video edited to show the main steps of the procedure of laparoscopic hernia repair and thoracoscopic lower left lobectomy. Video available at: https://www.jtcvs.org/article/S2666-2507(22)00472-2/fulltext. Download .jpg (.19 MB) Help with files Video 1Video edited to show the main steps of the procedure of laparoscopic hernia repair and thoracoscopic lower left lobectomy. Video available at: https://www.jtcvs.org/article/S2666-2507(22)00472-2/fulltext. - AXL and MET Tyrosine Kinase Receptors Co-Expression as a Potential Therapeutic Target in Malignant Pleural Mesothelioma
Federica Zito Marino, Carminia Maria Della Corte, Vincenza Ciaramella, Stefania Erra, Andrea Ronchi, Alfonso Fiorelli, Giovanni Vicidomini, Mario Santini, Giosuè Scognamiglio, Floriana Morgillo, Fortunato Ciardiello, Renato Franco, Marina Accardo
Journal of Personalized Medicine, 2022
Malignant pleural mesothelioma (MPM) is a highly lethal malignancy that unfortunately cannot benefit from molecularly targeted therapies. Although previous results showed the pivotal role of various receptor tyrosine kinases (RTKs) in MPM tumorigenesis, the treatment with a single inhibitor targeting one specific RTK has been shown to be ineffective in MPM patients. The main aim of the present study was to investigate the potential role of AXL and MET receptors in MPM and the possible efficacy of treatment with AXL and MET multitarget inhibitors. Immunohistochemical and FISH analyses were performed in a wide series of formalin-fixed paraffin-embedded MPM samples to detect the expression of two receptors and the potential gene amplification. In vitro studies were performed to evaluate putative correlations between the target’s expression and the cell sensitivity to AXL-MET multitarget inhibitors. In our series, 10.4% of cases showed a co-expression of AXL and MET, regardless of their ligand expression, and the gene amplification. Furthermore, our in vitro results suggest that the concomitant pharmacological inhibition of AXL and MET may affect the proliferative and aggressiveness of MPM cells. In conclusion, the subset of MPM patients with AXL-MET co-activation could benefit from treatment with specific multitarget inhibitors. - Ultrasound location of ground-glass opacity during thoracoscopic surgery
Gaetana Messina, Mary Bove, Giovanni Natale, Antonio Noro, Mario Martone, Giorgia Opromolla, Vincenzo Di Filippo, Beatrice Leonardi, Morena Fasano, Rita Polito, Alfonso Fiorelli, Mario Santini, Giovanni Vicidomini
Interactive Cardiovascular and Thoracic Surgery, 2022 - Prediction of preoperative intrathoracic adhesions for ipsilateral reoperations: sliding lung sign
Gaetana Messina, Mary Bove, Antonio Noro, Giorgia Opromolla, Giovanni Natale, Francesco Leone, Vincenzo Di Filippo, Beatrice Leonardi, Mario Martone, Mario Pirozzi, Marianna Caterino, Sergio Facchini, Alessia Zotta, Giovanni Vicidomini, Mario Santini, Alfonso Fiorelli, Della Corte Carminia, Fortunato Ciardiello, Morena Fasano
Journal of Cardiothoracic Surgery, 2022 - Intraoperative ultrasound: “Alternative eye” in lymph nodal dissection in non-small cell lung cancer
Gaetana Messina, Mary Bove, Antonio Noro, Giorgia Opromolla, Giovanni Natale, Rosa Mirra, Francesca Capasso, Davide Gerardo Pica, Vincenzo Di Filippo, Mario Pirozzi, Marianna Caterino, Sergio Facchini, Alessia Zotta, Rita Polito, Giovanni Vicidomini, Mario Santini, Alfonso Fiorelli, Fortunato Ciardiello, Morena Fasano
Thoracic Cancer, 2022 - Collateral Ventilation Effect After Endoscopic Recanalization of Malignant Stenosis
Alfonso Fiorelli, Gaetana Messina, Mario Santini
Archivos De Bronconeumologia, 2022 - Left upper lobectomy in a patient with congenital pericardial defect
Alfonso Fiorelli, Giovanni Natale, Vincenzo Di Filippo, Giorgia Opromolla, Giovanni Vicidomini, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2022 - Did conversion to thoracotomy during thoracoscopic lobectomy increase post-operative complications and prejudice survival? Results of best evidence topic analysis
Alfonso Fiorelli, Stefano Forte, Mario Santini, René Horsleben Petersen, Wentao Fang
Thoracic Cancer, 2022 - Management of residual spaces after lung resections and air leaks: Ultrasound and pneumoperitoneum
Gaetana Messina, Antonio Noro, Giovanni Natale, Mary Bove, Morena Fasano, Giovanni Vicidomini, Mario Santini, Alfonso Fiorelli
Interactive Cardiovascular and Thoracic Surgery, 2022 - The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment
Gaetana Messina, Nicola Tartaglia, Antonio Ambrosi, Chiara Porro, Angelo Campanozzi, Anna Valenzano, Gaetano Corso, Alfonso Fiorelli, Rita Polito, Mario Santini, Marcellino Monda, Domenico Tafuri, Giovanni Messina, Antonietta Messina, Vincenzo Monda
Life, 2022 - Ultrasound for Assessment and Follow-up of Airway Stenosis
Alfonso Fiorelli, Gaetana Messina, Mary Bove, Giovanni Natale, Antonio Noro, Roberto Cascone, Giorgia Opromolla, Domenico Testa, Gaetano Motta, Mario Santini
Annals of Thoracic Surgery, 2022 - The use of ultrasound in the evaluation of postoperative pneumothorax and lung re-expansion in patients after lung resection
Annali Italiani Di Chirurgia, 2022 - Stapler stuck to the lung tissue during thoracoscopic lobectomy: A case report
Alfonso Fiorelli, Giovanni Natale, Fausto Ferraro, Roberta Fiorito, Mario Santini
Shanghai Chest, 2022 - Endotracheal tube for relocating dislocated airway stent: A case report
Alfonso Fiorelli, Gaetana Messina, Roberta Fiorito, Mario Martone, Fausto Ferraro, Mario Santini
Shanghai Chest, 2022 - Application of ERAS Protocol after VATS Surgery for Chronic Empyema in Immunocompromised Patients
Beatrice Leonardi, Caterina Sagnelli, Alfonso Fiorelli, Francesco Leone, Rosa Mirra, Davide Gerardo Pica, Vincenzo Di Filippo, Francesca Capasso, Gaetana Messina, Giovanni Vicidomini, Antonello Sica, Mario Santini
Healthcare Switzerland, 2022 - Adjuvant chemotherapy, extent of resection, and immunoistochemical neuroendocrine markers as prognostic factors of early-stage large-cell neuroendocrine carcinoma
Claudio Andreetti, Mohsen Ibrahim, Antonio Gagliardi, Camilla Poggi, Giulio Maurizi, Domenico Armillotta, Valentina Peritone, Leonardo Teodonio, Erino Angelo Rendina, Federico Venuta, Marco Anile, Giovanni Natale, Mario Santini, Alfonso Fiorelli
Thoracic Cancer, 2022 - Does airway metallic stent limit additional treatments in patients with malignant airway stenosis?
Alfonso Fiorelli, Gaetana Messina, Alfonso Pecoraro, Mario Santini
General Thoracic and Cardiovascular Surgery, 2022 - The Potential Role of Nutrition in Lung Cancer Establishment and Progression
Chiara Porro, Maria Ester La Torre, Nicola Tartaglia, Tarek Benameur, Mario Santini, Antonio Ambrosi, Giovanni Messina, Giuseppe Cibelli, Alfonso Fiorelli, Rita Polito, Gaetana Messina
Life, 2022 - Leveraging CycleGAN in Lung CT Sinogram-free Kernel Conversion
Michela Gravina, Stefano Marrone, Ludovico Docimo, Mario Santini, Alfonso Fiorelli, Domenico Parmeggiani, Carlo Sansone
Lecture Notes in Computer Science, 2022 - Smart biomaterials and constructs for cardiac tissue regeneration
Antonio Noro, Beatrice Leonardi, Giovanni Natale, Mary Bove, Mario Martone, Davide Gerardo Pica, Francesco Leone, Rosa Mirra, Mario Santini, Alfonso Fiorelli
New Trends in Smart Nanostructured Biomaterials in Health Sciences, 2022 - A trimodality, four-step treatment including chemotherapy, pleurectomy/decortication and radiotherapy in early-stage malignant pleural mesothelioma: A single-institution retrospective case series study
Giovanni Vicidomini, Carminia Maria Della Corte, Antonio Noro, Raimondo Di Liello, Salvatore Cappabianca, Alfonso Fiorelli, Valerio Nardone, Gaetana Messina, Giuseppe Viscardi, Angelo Sangiovanni, Riccardo Monti, Marina Accardo, Floriana Morgillo, Fortunato Ciardiello, Renato Franco, Mario Santini
Cancers, 2022 - Three-Dimensional Printed Models for Preoperative Planning and Surgical Treatment of Chest Wall Disease: A Systematic Review
Beatrice Leonardi, Annalisa Carlucci, Antonio Noro, Mary Bove, Giovanni Natale, Giorgia Opromolla, Rosa Mirra, Davide Pica, Francesca Capasso, Vincenzo Di Filippo, Gaetana Messina, Francesco Ferrigno, Anna Cecilia Izzo, Giovanni Vicidomini, Mario Santini, Alfonso Fiorelli
Technologies, 2021 - Percutaneous dilation tracheostomy in a patient with tracheal stent
Alfonso Fiorelli, Gaetana Messina, Mario Santini, Fausto Ferraro
Interactive Cardiovascular and Thoracic Surgery, 2021 - New trends in precision medicine: A pilot study of pure light scattering analysis as a useful tool for non-small cell lung cancer (nsclc) diagnosis
Domenico Rossi, David Dannhauser, Bianca Maria Nastri, Andrea Ballini, Alfonso Fiorelli, Mario Santini, Paolo Antonio Netti, Salvatore Scacco, Maria Michela Marino, Filippo Causa, Mariarosaria Boccellino, Marina Di Domenico
Journal of Personalized Medicine, 2021 - Hemopatch to Fix Mobile Lobe after Thoracoscopic Lobectomy
Alfonso Fiorelli, Annalisa Carlucci, Roberto Cascone, Mario Santini
Thoracic and Cardiovascular Surgeon, 2021 - Human lung-resident macrophages express and are targets of thymic stromal lymphopoietin in the tumor microenvironment
Mariantonia Braile, Alfonso Fiorelli, Daniela Sorriento, Rosa Maria Di Crescenzo, Maria Rosaria Galdiero, Gianni Marone, Mario Santini, Gilda Varricchi, Stefania Loffredo
Cells, 2021 - Pulmonary Hamartoma Associated With Lung Cancer (PHALC Study): Results of a Multicenter Study
Alfonso Fiorelli, Antonio D’Andrilli, Annalisa Carlucci, Giovanni Vicidomini, Giacomo Argento, Beatrice Trabalza Marinucci, Francesco Ardissone, Roberta Rapanà, Simona Sobrero, Paolo Carbognani, Luigi Ventura, Giovanni Bocchialini, Mark Ragusa, Valentina Tassi, Francesco Sollitto, Domenico Loizzi, Nicoletta Pia Ardò, Marco Anile, Francesco Puma, Erino Angelo Rendina, Federico Venuta, Nicola Serra, Mario Santini
Lung, 2021 - PercuTwist tracheostomy in an intubated patient with tracheal stent
Mary Bove, Fausto Ferraro, Floriana Morgillo, Giovanni Natale, Mario Santini, Alfonso Fiorelli
Asian Cardiovascular and Thoracic Annals, 2021 - Ultrasound-guided anterior mediastinotomy: A feasible tool for critical lymphoma patients
Roberto Cascone, Annalisa Carlucci, Gaetana Messina, Antonio Noro, Mary Bove, Giovanni Natale, Caterina Sagnelli, Giorgia Opromolla, Mario Martone, Carlo Santoriello, Elena Santoriello, Pasquale Verolino, Massimiliano Creta, Giovanni Vicidomini, Alfonso Fiorelli, Mario Santini, Antonello Sica
Healthcare Switzerland, 2021 - Handling benign interlobar lymphadenopathy during thoracoscopic lobectomy
Alfonso Fiorelli, Stefano Forte, Giovanni Natale, Mario Santini, Wentao Fang
Thoracic Cancer, 2021 - Subxifoid versus transthoracic thoracoscopic lobectomy: Results of a retrospective analysis before and after matching analysis
Claudio Andreetti, Valentina Peritore, Mohsen Ibrahim, Antonio Gagliardi, Giacomo Argento, Giulio Maurizi, Leonardo Teodonio, Nicola Serra, Erino Angelo Rendina, Mario Santini, Alfonso Fiorelli
Thoracic Cancer, 2021 - Novel Duck Bill-Shaped Laryngotracheal Stent for Management of Subglottic Stenosis
Claudio Andreetti, Erino Angelo Rendina, Mario Santini, Alfonso Fiorelli
Annals of Thoracic Surgery, 2021 - Is video-assisted thoracoscopic lobectomy associated with higher overall costs compared with open surgery? Results of best evidence topic analysis
Alfonso Fiorelli, Stefano Forte, Francesco Paolo Caronia, Francesco Ferrigno, Mario Santini, René Horsleben Petersen, Wentao Fang
Thoracic Cancer, 2021 - Uniportal thoracoscopic surgical management using a suture traction for primary pneumothorax
Alfonso Fiorelli, Roberto Cascone, Annalisa Carlucci, Giovanni Natale, Chiara Freda, Mary Bove, Gaetana Messina, Giovanni Liguori, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2021 - Double-staining Immunohistochemistry Reveals in Malignant Pleural Mesothelioma the Coexpression of ERCC1 and RRM1 as a Frequent Biological Event Related to Poorer Survival
Federica Zito Marino, Simona Baselice, Stefania Erra, Andrea Ronchi, Marco Montella, Floriana Morgillo, Giovanni Vicidomini, Mario Santini, Giuseppina Poziello, Immacolata Cozzolino, Marina Accardo, Renato Franco
Applied Immunohistochemistry and Molecular Morphology, 2021 - Tissue Engineering in Musculoskeletal Tissue: A Review of the Literature
Mary Bove, Annalisa Carlucci, Giovanni Natale, Chiara Freda, Antonio Noro, Vincenzo Ferrara, Giorgia Opromolla, Mario Martone, Roberto Cascone, Gaetana Messina, Anna Izzo, Giovanni Vicidomini, Mario Santini, Alfonso Fiorelli
Surgeries Switzerland, 2021 - Endoscopic resection of tracheal lobular capillary haemangioma with ultrasonically activated device
Alfonso Fiorelli, Marina Accardo, Pietro Venetucci, Roberto Cascone, Annalisa Carlucci, Antonio Noro, Vincenzo Ferrara, Giovanni Natale, Vincenzo Napolitano, Mario Santini
General Thoracic and Cardiovascular Surgery, 2021 - Macrophage-polarizing stimuli differentially modulate the inflammatory profile induced by the secreted phospholipase A2 group IA in human lung macrophages
Anne Lise Ferrara, Maria Rosaria Galdiero, Alfonso Fiorelli, Leonardo Cristinziano, Francescopaolo Granata, Giancarlo Marone, Rosa Maria Di Crescenzo, Mariantonia Braile, Simone Marcella, Luca Modestino, Gilda Varricchi, Giuseppe Spadaro, Mario Santini, Stefania Loffredo
Cytokine, 2021 - The lidocaine patch: Features and applications: Post-thoracotomy pain and beyond
Alfonso Fiorelli, Pasquale Sansone, Caterina Pace, Mario Santini
Treatments Mechanisms and Adverse Reactions of Anesthetics and Analgesics, 2021 - Inherited predisposition to malignant mesothelioma: germline BAP1 mutations and beyond
F. Pagliuca, F. Zito Marino, F. Morgillo, C. D. Della Corte, M. Santini, G. Vicidomini, G. Guggino, G. de Dominicis, S. Campione, M. Accardo, I. Cozzolino, R. Franco
European Review for Medical and Pharmacological Sciences, 2021 - Survival after video-assisted thoracoscopic surgery for lung metastasectomy
Alfonso Fiorelli, Annalisa Carlucci, Giovanni Natale, Mary Bove, Chiara Freda, Antonio Noro, Vincenzo Ferrara, Giorgia Opromolla, Mario Martone, Roberto Cascone, Gaetana Messina, Anna Izzo, Giovanni Vicidomini, Mario Santini
Video Assisted Thoracic Surgery, 2021 - Management of vascular injury during VATS lobectomy with hemostatic matrix sealant agent: a case report
Roberto Cascone, Alfonso Fiorelli, Vincenzo Ferrara, Antonio Noro, Annalisa Carlucci, Mario Santini
Mediastinum, 2020 - The use of Transcollation Technology for Video-Assisted Thoracic Surgery lobectomy
Cecilia Menna, Camilla Poggi, Claudio Andreetti, Anna Maria Ciccone, Alberto Emiliano Baccarini, Giulio Maurizi, Antonio D’Andrilli, Camilla Vanni, Roberto Cascone, Alfonso Fiorelli, Mario Santini, Federico Venuta, Erino Angelo Rendina, Mohsen Ibrahim
Journal of Cardiothoracic Surgery, 2020 - Does the length of uniportal video-assisted thoracoscopic lobectomy affect postoperative pain? Results of a randomized controlled trial
Cecilia Menna, Camilla Poggi, Claudio Andreetti, Giulio Maurizi, Anna Maria Ciccone, Antonio D'Andrilli, Camilla Vanni, Anna Rita Vestri, Alfonso Fiorelli, Mario Santini, Federico Venuta, Erino Angelo Rendina, Mohsen Ibrahim
Thoracic Cancer, 2020 - Dilation of tracheal stenosis below tracheostomy tube with Dolphin percutaneous tracheostomy kit: Tracheal stenosis treated with Dolphin PDT
Alfonso Fiorelli, Mary Bove, Antonio Noro, Angela Iuorio, Mario Santini, Fausto Ferraro
General Thoracic and Cardiovascular Surgery, 2020 - Cardio-Pulmonary Changes After Bronchoscopic Lung Volume Reduction with Endobronchial One-Way Valves
Alfonso Fiorelli, Roberto Cascone, Giovanni Natale, Valentina Peritore, Camilla Vanni, Camilla Poggi, Federico Venuta, Erino Angelo Rendina, Mario Santini, Claudio Andreetti
Lung, 2020 - Endoscopic treatment and pulmonary rehabilitation for management of lung abscess in elderly lymphoma patients
Roberto Cascone, Antonello Sica, Caterina Sagnelli, Annalisa Carlucci, Armando Calogero, Mario Santini, Alfonso Fiorelli
International Journal of Environmental Research and Public Health, 2020 - Surgical treatment of lung cancer with adjacent lobe invasion in relation to fissure integrity
Claudio Andreetti, Camilla Poggi, Mohsen Ibrahim, Antonio D'Andrilli, Giulio Maurizi, Matteo Tiracorrendo, Valentina Peritore, Erino Angelo Rendina, Federico Venuta, Marco Anile, Andreina Pagini, Giovanni Natale, Mario Santini, Alfonso Fiorelli
Thoracic Cancer, 2020 - Prognostic factors of lung cancer in lymphoma survivors (the LuCiLyS study)
Alfonso Fiorelli, , Antonio D’Andrilli, Annalisa Carlucci, Giovanni Vicidomini, Domenico Loizzi, Nicoletta Pia Ardò, Rita Daniela Marasco, Luigi Ventura, Luca Ampollini, Paolo Carbognani, Giovanni Bocchialini, Filippo Lococo, Massimiliano Paci, Teresa Severina Di Stefano, Francesco Ardissone, Matteo Gagliasso, Paolo Mendogni, Lorenzo Rosso, Alessandra Mazzucco, Camilla Vanni, Beatrice Trabalza Marinucci, Rossella Potenza, Alberto Matricardi, Mark Ragusa, Valentina Tassi, Marco Anile, Camilla Poggi, Nicola Serra, Antonello Sica, Mario Nosotti, Francesco Sollitto, Federico Venuta, Erino Angelo Rendina, Francesco Puma, Mario Santini
Translational Lung Cancer Research, 2020 - Best Evidence Topic: Does the Depth of Sedation Affect Diagnostic Yield of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration?
Alfonso Fiorelli, Alfonso Pecoraro, Annalisa Carlucci, Mario Santini, Pallav L. Shah, Vincent Wentao Fang
Clinical Pulmonary Medicine, 2020 - Diagnostic and prognostic role of liquid biopsy in non-small cell lung cancer: evaluation of circulating biomarkers
Giovanni Vicidomini, Roberto Cascone, Annalisa Carlucci, Alfonso Fiorelli, Marina Di Domenico, Mario Santini
Exploration of Targeted Anti Tumor Therapy, 2020 - The use of 3D printing model as tool for planning endoscopic treatment of benign airway stenosis
Giovanni Natale, Alfonso Reginelli, Domenico Testa, Gaetano Motta, Vincent Fang, Mario Santini, Alfonso Fiorelli
Translational Cancer Research, 2020 - Montgomery T-tube for management of tracheomalacia: Impact on voice-related quality of life
Alfonso Fiorelli, Giovanni Natale, Chiara Freda, Roberto Cascone, Annalisa Carlucci, Saveria Costanzo, Vincenzo Ferrara, Mario Santini
Clinical Respiratory Journal, 2020 - Pronounced dys-autonomic symptoms announcing a primary sjögren’s syndrome
F. Masini, L. Monaco, K. Gjeloshi, E. Pinotti, R. Ferrrara, P.C. Pafundi, M. Santini, T. Salvatore, G. Cuomo
Reumatismo, 2020 - Adequacy of cytologic samples by ultrasound-guided percutaneous transthoracic fine-needle aspiration cytology of peripheral pulmonary nodules for morphologic diagnosis and molecular evaluations comparison with computed tomography-guided percutaneous transthoracic fine-needle aspiration cytology
Immacolata Cozzolino, Andrea Ronchi, Gaetana Messina, Marco Montella, Floriana Morgillo, Giovanni Vicidomini, Virginia Tirino, Anna Grimaldi, Federica Zito Marino, Mario Santini, Salvatore Cappabianca, Renato Franco
Archives of Pathology and Laboratory Medicine, 2020 - Pembrolizumab monotherapy in advanced NSCLC patients with low PD-L1 expression: Is there real evidence?
Alfonso Fiorelli, Fabiana Vitiello, Floriana Morgillo, Mario Santagata, Chiara Spuntarelli, Marina Di Domenico, Mario Santini, Andrea Bianco
Translational Cancer Research, 2019 - Proteomics analysis of human serum of patients with non-small-cell lung cancer reveals proteins as diagnostic biomarker candidates
Mariarosaria Boccellino, Federica Pinto, Vincenzo Ieluzzi, Alfonso Giovane, Lucio Quagliuolo, Chiara Fariello, Mario Coppola, Annalisa Carlucci, Mario Santini, Kenan Ferati, Arbëresha Bexheti‐Ferati, Antonio Giordano, Marina Di Domenico
Journal of Cellular Physiology, 2019 - Combined intrapleural and intrabronchial injection of fibrin glue for closing alveolar pleural fistula: A case report
Alfonso Fiorelli, Italia Odierna, Daniele Scarano, Francesco Caronia, Andrea Failla, Mario Iannotti, Mario Santini, Caterina Pace
Journal of Cardiothoracic Surgery, 2019 - Endoscopic one-way endobronchial valves in the treatment of persistent air leak with empyema
Giacomo Cusumano, Alfonso Fiorelli, Salvatore Bellofiore, Carmelo Riscica Lizzio, Rosalia Giarlotta, Mario Santini, Alberto Terminella
Shanghai Chest, 2019 - Flow-Volume Curve Analysis for Predicting Recurrence After Endoscopic Dilation of Airway Stenosis
Alfonso Fiorelli, Camilla Poggi, Nicoletta Pia Ardò, Gaetana Messina, Claudio Andreetti, Federico Venuta, Erino Angelo Rendina, Mario Santini, Michele Loizzi, Nicola Serra, Francesco Sollitto, Domenico Loizzi
Annals of Thoracic Surgery, 2019 - Antitumor activity of dual blockade of PD-L1 and MEK in NSCLC patients derived three-dimensional spheroid cultures
Carminia Maria Della Corte, Giusi Barra, Vincenza Ciaramella, Raimondo Di Liello, Giovanni Vicidomini, Silvia Zappavigna, Amalia Luce, Marianna Abate, Alfonso Fiorelli, Michele Caraglia, Mario Santini, Erika Martinelli, Teresa Troiani, Fortunato Ciardiello, Floriana Morgillo
Journal of Experimental and Clinical Cancer Research, 2019 - Nanoparticle-biomolecular corona: A new approach for the early detection of non-small-cell lung cancer
Marina Di Domenico, Daniela Pozzi, Sara Palchetti, Luca Digiacomo, Rosamaria Iorio, Carlo Astarita, Alfonso Fiorelli, Matteo Pierdiluca, Mario Santini, Marcella Barbarino, Antonio Giordano, Angelina Di Carlo, Luigi Frati, Morteza Mahmoudi, Giulio Caracciolo
Journal of Cellular Physiology, 2019 - Visual analysis versus quantitative CT analysis of interlobar fissure integrity in selecting emphysematous patients for endobronchial valve treatment
Alfonso Fiorelli, Camilla Poggi, Marco Anile, Roberto Cascone, Annalisa Carlucci, Francesco Cassiano, Claudio Andreetti, Matteo Tiracorrendo, Daniele Diso, Nicola Serra, Federico Venuta, Erino Angelo Rendina, Mario Santini, Antonio D’Andrilli
Interactive Cardiovascular and Thoracic Surgery, 2019 - Endobronchial Ultrasound for Benign Tracheal Stenosis
Alfonso Fiorelli, Gaetana Messina, Carlo Santoriello, Mario Santini
Thoracic and Cardiovascular Surgeon, 2019 - Preventive skin analgesia with lidocaine patch for management of post-thoracotomy pain: Results of a randomized, double blind, placebo controlled study
Alfonso Fiorelli, Caterina Pace, Roberto Cascone, Annalisa Carlucci, Emanuele De Ruberto, Anna Cecilia Izzo, Beatrice Passavanti, Paolo Chiodini, Vincenzo Pota, Caterina Aurilio, Mario Santini, Pasquale Sansone
Thoracic Cancer, 2019 - Endoscopic central airway recanalization to enable first line pembrolizumab treatment in a PD-L1 strongly positive non-small cell lung cancer: A case report
Alfonso Fiorelli, Fabio Perrotta, Mariano Mollica, Mario Santini, Fabiana Vitiello, Marina Gilli, Cecilia Calabrese, Andrea Bianco
Journal of Cardiothoracic Surgery, 2019 - Is thymomectomy equivalent to complete thymectomy in non-myasthenic patients with early-stage thymoma?
Alfonso Fiorelli, Giovanni Natale, Chiara Freda, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2019 - Reply
Claudio Andreetti, Matteo Tiracorrendo, Erino Angelo Rendina, Mario Santini, Alfonso Fiorelli
Annals of Thoracic Surgery, 2019 - Insert: Surgical Operative Procedures Suggested by an Expert
Mario Santini, Alfonso Fiorelli
Malignant Pleural Mesothelioma A Guide for Clinicians, 2019 - Tailored airway stent: The new frontiers of the endoscopic treatment of broncho-pleural fistula
Alfonso Fiorelli, Vincenzo Ferrara, Mary Bove, Mario Santini
Journal of Thoracic Disease, 2019 - Fibrin glue to fix metallic airway stent
Alfonso Fiorelli, Gaetana Messina, Carlo Santoriello, Giovanni Liguori, Ettore Arrigo, Francesco Paolo Caronia, Mario Santini
Journal of Thoracic Disease, 2019 - A modified technique to simplify external fixation of the subglottic silicone stent
Claudio Andreetti, Cecilia Menna, Antonio D’Andrilli, Mohsen Ibrahim, Federico Venuta, Mario Santini, Erino Angelo Rendina, Alfonso Fiorelli
Interactive Cardiovascular and Thoracic Surgery, 2018 - Multimodal Treatment for Post-Pneumonectomy Bronchopleural Fistula Associated With Empyema
Claudio Andreetti, Cecilia Menna, Antonio D'Andrilli, Mohsen Ibrahim, Giulio Maurizi, Camilla Poggi, Erino Angelo Rendina, Federico Venuta, Mario Santini, Alfonso Fiorelli
Annals of Thoracic Surgery, 2018 - Unidirectional endobronchial valves for management of persistent air-leaks: Results of a multicenter study
Alfonso Fiorelli, Antonio D’Andrilli, Roberto Cascone, Luisa Occhiati, Marco Anile, Daniele Diso, Francesco Cassiano, Camilla Poggi, Mohsen Ibrahim, Giacomo Cusumano, Alberto Terminella, Giuseppe Failla, Alba La Sala, Michela Bezzi, Margherita Innocenti, Elena Torricelli, Federico Venuta, Erino Angelo Rendina, Giovanni Vicidomini, Mario Santini, Claudio Andreetti
Journal of Thoracic Disease, 2018 - Three-dimensional (3D) Printed Model to Plan the Endoscopic Treatment of Upper Airway Stenosis
Alfonso Fiorelli, Roberto Scaramuzzi, Ivana Minerva, Emanuele De Ruberto, Teresa Califano, Alfonso Reginelli, Roberto Grassi, Mario Santini
Journal of Bronchology and Interventional Pulmonology, 2018 - Life-threatening central air-way obstruction caused by misdiagnosed migration of silicone tracheal stent
Annalisa Carlucci, Gaetana Messina, Roberto Cascone, Massimo Ingenito, Damiano Capaccio, Mario Santini, Alfonso Fiorelli
Shanghai Chest, 2018 - The renaissance of photodynamic therapy for early esophageal cancer: Is it the time?
Alfonso Fiorelli, Aldo Prencipe, Mario Santini
Journal of Thoracic Disease, 2018 - A simplified insertion technique for tracheal T-tube
Alfonso Fiorelli, Annalisa Carlucci, Vincenzo Pota, Mario Santini
Journal of Thoracic and Cardiovascular Surgery, 2018 - The use of ultrasound in detecting and defining ground-glass opacities: Results of an ex vivo evaluation
Alfonso Fiorelli, Gaetana Messina, Elisabetta Frongillo, Marina Accardo, Marco Montella, Iacopo Panarese, Renato Franco, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2018 - Uniportal thoracoscopy combined with laparoscopy as minimally invasive treatment of esophageal cancer
Francesco Paolo Caronia, Ettore Arrigo, Andrea Valentino Failla, Francesco Sgalambro, Giorgio Giannone, Attilio Ignazio Lo Monte, Massimo Cajozzo, Mario Santini, Alfonso Fiorelli
Journal of Thoracic Disease, 2018 - When can computed tomography-fissure analysis replace Chartis collateral ventilation assessment in the prediction of patients with emphysema who might benefit from endobronchial valve therapy?
Alfonso Fiorelli, Mario Santini, Pallav Shah
Interactive Cardiovascular and Thoracic Surgery, 2018 - Endoscopic treatment of idiopathic subglottic stenosis with digital AcuBlade robotic microsurgery system
Alfonso Fiorelli, Salvatore Mazzone, Giuseppe Costa, Mario Santini
Clinical Respiratory Journal, 2018 - The use of ultrasound in the management of a life-threatening malignant laryngotracheal obstruction
Alfonso Fiorelli, Gaetana Messina, Antonio Raucci, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2018 - Endoscopic management of critical neoplastic central airway obstruction
Alfonso Fiorelli, Roberto Cascone, Davide Di Natale, Annalisa Carlucci, Gaetana Messina, Emanuele De Ruberto, Giovanni Liguori, Vincenzo Pota, Filomena Peluso, Luigi Ferrante, Mario Santini
Shanghai Chest, 2018 - Lobar or sublobar resection for stage I lung cancer: That is (still) the question!
Alfonso Fiorelli, Domenico Loizzi, Mario Santini
Journal of Thoracic Disease, 2018 - Complications related to endoscopic lung volume reduction for emphysema with endobronchial valves: Results of a multicenter study
Alfonso Fiorelli, Antonio D’Andrilli, Michela Bezzi, Mohsen Ibrahim, Marco Anile, Daniele Diso, Giacomo Cusumano, Alberto Terminella, Valentina Luzzi, Margherita Innocenti, Mauro Novali, Emanuele Carelli, Chiara Freda, Giovanni Natale, Valentina Peritore, Camilla Poggi, Giuseppe Failla, Marco Basile, Emilia Mazzucca, Serena Conforti, Nicola Serra, Massimo Torre, Federico Venuta, Erino Angelo Rendina, Mario Santini, Claudio Andreetti
Journal of Thoracic Disease, 2018 - Prognostic value of soluble major histocompatibility complex class I polypeptiderelated sequence A in non-small-cell lung cancer - Significance and development
Roberto Cascone, Annalisa Carlucci, Matteo Pierdiluca, Mario Santini, Alfonso Fiorelli
Lung Cancer Targets and Therapy, 2017 - Percutaneous dilatational tracheostomy using the ETView Tracheoscopic Ventilation Tube®: a teaching course in a pig model
Alfonso Fiorelli, Fausto Ferraro, Elisabetta Frongillo, Pierluigi Fusco, Matteo Pierdiluca, Francesca Nagar, Angela Iuorio, Mario Santini
Journal of Anesthesia, 2017 - Comparison of plethysmographic and helium dilution lung volumes in patients with a giant emphysematous bulla as selection criteria for endobronchial valve implant
Alfonso Fiorelli, Roberto Scaramuzzi, Matteo Pierdiluca, Elisabetta Frongillo, Gaetana Messina, Nicola Serra, Alberto De Felice, Mario Santini
European Journal of Cardio Thoracic Surgery, 2017 - The role of video-assisted thoracoscopic surgery for management of symptomatic pleural effusion after coronary artery bypass surgery: A best evidence topic report
Alfonso Fiorelli, Francesco Caronia, Aldo Prencipe, Mario Santini, Brendon Stiles
Journal of Thoracic Disease, 2017 - Total intravenous anaesthesia with local anaesthesia for controlling pain after spontaneous ventilation video-assisted thoracic surgery: Is it a viable strategy?
Alfonso Fiorelli, Mario Santini
European Journal of Cardio Thoracic Surgery, 2017 - Results of the safety run-in part of the METAL (METformin in Advanced Lung cancer) study: A multicentre, open-label phase I-II study of metformin with erlotinib in second-line therapy of patients with stage IV non-small-cell lung cancer
Floriana Morgillo, Morena Fasano, Carminia Maria Della Corte, Ferdinando Carlo Sasso, Federica Papaccio, Giuseppe Viscardi, Giovanna Esposito, Raimondo Di Liello, Nicola Normanno, Annalisa Capuano, Liberato Berrino, Giovanni Vicidomini, Alfonso Fiorelli, Mario Santini, Fortunato Ciardiello
ESMO Open, 2017 - In the era of ultrasound technology, could conventional transbronchial needle aspiration still play a role in lung cancer mediastinal staging?
Alfonso Fiorelli, Carlo Santoriello, Davide Di Natale, Roberto Cascone, Valentina Musella, Rossella Mastromarino, Nicola Serra, Giovanni Vicidomini, Mario Polverino, Mario Santini
Journal of Thoracic Disease, 2017 - Uniportal Video-Assisted Thoracoscopic Surgery Resection of a Giant Midesophageal Diverticulum
Francesco Paolo Caronia, Alfonso Fiorelli, Mario Santini, Attilio Ignazio Lo Monte
Annals of Thoracic Surgery, 2017 - A New Modified Evans Blue Dye Test as Screening Test for Aspiration in Tracheostomized Patients
Alfonso Fiorelli, Fausto Ferraro, Francesca Nagar, Pierluigi Fusco, Salvatore Mazzone, Giuseppe Costa, Davide Di Natale, Nicola Serra, Mario Santini
Journal of Cardiothoracic and Vascular Anesthesia, 2017 - Trans-tracheostomy repair of tracheo-esophageal fistula under endoscopic view in a 75-year-old woman
Francesco Paolo Caronia, Alfonso Reginelli, Mario Santini, Roberto Alfano, Sebastiano Trovato, Ettore Arrigo, Alfonso Fiorelli
Journal of Thoracic Disease, 2017 - A conical self-expanding metallic stent for the management of critical complex tracheobronchial malignant stenosis
Alfonso Fiorelli, Umberto Caterino, Antonio Raucci, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2017 - Iterative Surgical Treatment for Repeated Recurrences After Complete Resection of Thymic Tumors
Alfonso Fiorelli, Antonio D'Andrilli, Camilla Vanni, Roberto Cascone, Marco Anile, Daniele Diso, Valentina Tassi, Jacopo Vannucci, Nicola Serra, Francesco Puma, Erino Angelo Rendina, Federico Venuta, Mario Santini
Annals of Thoracic Surgery, 2017 - A new technique for treatment of tracheal stenosis
Sandro Batzella, Gabriele Lucantoni, Giovanni Galluccio, Mario Santini, Umberto Caterino, et al.
Multimedia Manual of Cardiothoracic Surgery Mmcts, 2017 - Endoscopic hand drill for management of tracheal stenosis
Sandro Batzella, Gabriele Lucantoni, Giovanni Galluccio, Mario Santini, Umberto Caterino, et al.
Multimedia Manual of Cardiothoracic Surgery Mmcts, 2017 - Ultrasonic Technology for Management of Primary Spontaneous Pneumothorax
Antonio Mazzella, Marina Accardo, Mario Santini, Alfonso Fiorelli
Thoracic and Cardiovascular Surgeon, 2017 - Routine invasive mediastinal staging of lung cancer in elderly patients without lymph adenopathy on pet-ct scan: Is an appropriate choice?
Journal of Gerontology and Geriatrics, 2017 - Cardiac Autonomic Changes After Thoracic Sympathectomy: A Prospective, Randomized Study
Alfonso Fiorelli, Giovanni Messina, Paolo Chiodini, Saveria Costanzo, Andrea Viggiano, Marcellino Monda, Giovanni Vicidomini, Mario Santini
Annals of Thoracic Surgery, 2017 - Three-dimensional virtual bronchoscopy using a tablet computer to guide real-time transbronchial needle aspiration
Alfonso Fiorelli, Antonio Raucci, Roberto Cascone, Alfonso Reginelli, Davide Di Natale, Carlo Santoriello, Antonio Capuozzo, Roberto Grassi, Nicola Serra, Mario Polverino, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2017 - Small bowel metastasis from pancreatic cancer in a long-term survival patient with synchronous advanced malignant pleural mesothelioma: A case report and literature review
Morena Fasano, Carminia Maria Della Corte, Giovanni Vicidomini, Valerio Scotti, Pier Francesco Rambaldi, Alfonso Fiorelli, Marina Accardo, Ferdinando De Vita, Mario Santini, Fortunato Ciardiello, Floriana Morgillo
Oncology Letters, 2016 - Sublobar resection versus lobectomy for stage I non-small cell lung cancer: an appropriate choice in elderly patients?
Alfonso Fiorelli, Francesco Paolo Caronia, Niccolò Daddi, Domenico Loizzi, Luca Ampollini, Nicoletta Ardò, Luigi Ventura, Paolo Carbognani, Rossella Potenza, Francesco Ardissone, Francesco Sollitto, Sandro Mattioli, Francesco Puma, Mario Santini, Mark Ragusa
Surgery Today, 2016 - Bilateral single-port thoracoscopic extended thymectomy for management of thymoma and myasthenia gravis: Case report
Francesco Paolo Caronia, Alfonso Fiorelli, Ettore Arrigo, Sebastiano Trovato, Mario Santini, Attilio Ignazio Lo Monte
Journal of Cardiothoracic Surgery, 2016 - A persistent tracheocutaneous fistula closed with two hinged skin flaps and rib cartilage interpositional grafting
Francesco Paolo Caronia, Alfonso Fiorelli, Mario Santini, Sergio Castorina
General Thoracic and Cardiovascular Surgery, 2016 - A new technique to repair huge tracheo-gastric fistula following esophagectomy
Francesco Paolo Caronia, Alfonso Fiorelli, Mario Santini, Roberto Alfano, Sergio Castorina
Annals of Translational Medicine, 2016 - Bronchoscopic lung volume reduction: An alternative to repeated lung volume reduction surgery
Alfonso Fiorelli, Mario Santini
European Journal of Cardio Thoracic Surgery, 2016 - Endobronchial Valve Migration: A "whistle Blower"
Alfonso Fiorelli, Alfonso Reginelli, Mario Santini
Journal of Bronchology and Interventional Pulmonology, 2016 - Bilateral thoracoscopic extended thymectomy versus sternotomy
Alfonso Fiorelli, Antonio Mazzella, Roberto Cascone, Francesco Paolo Caronia, Ettore Arrigo, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2016 - A new endoscopic hand drill for management of tracheal stenosis
Sandro Batzella, Gabriele Lucantoni, Alfonso Fiorelli, Raffaele Dello Iacono, Paolo Battistoni, Umberto Caterino, Mario Santini, Giovanni Galluccio
Interactive Cardiovascular and Thoracic Surgery, 2016 - Sequential Bilateral Bronchoscopic Lung Volume Reduction with One-Way Valves for Heterogeneous Emphysema
Alfonso Fiorelli, Antonio D’Andrilli, Marco Anile, Daniele Diso, Camilla Poggi, Mario Polverino, Giuseppe Failla, Federico Venuta, Erino Angelo Rendina, Mario Santini
Annals of Thoracic Surgery, 2016 - Harmonic technology versus neodymium-doped yttrium aluminium garnet laser and electrocautery for lung metastasectomy: An experimental study
Alfonso Fiorelli, Marina Accardo, Emanuele Carelli, Assunta Del Prete, Gaetana Messina, Alfonso Reginelli, Daniela Berritto, Ferdinando Papale, Emilia Armenia, Paolo Chiodini, Roberto Grassi, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2016 - AcuBlade® laser system: A new tool for interventional bronchoscopist
Alfonso Fiorelli, Salvatore Mazzone, Mario Santini
Archivos De Bronconeumologia, 2016 - Management of subtotal tracheal section with esophageal perforation: A catastrophic complication of tracheostomy
Francesco Paolo Caronia, Alfonso Fiorelli, Ettore Arrigo, Mario Santini, Sergio Castorina
Journal of Thoracic Disease, 2016 - Reconstruction with a pectoralis major myocutaneous flap after left first rib and clavicular chest wall resection for a metastasis from laryngeal cancer
Francesco Paolo Caronia, Alfonso Fiorelli, Fabio Zanchini, Mario Santini, Attilio Ignazio Lo Monte, Sergio Castorina
General Thoracic and Cardiovascular Surgery, 2016 - Percutaneous dilatational tracheostomy using a tracheoscopic ventilation tube in an experimental ex vivo animal model
A. F. Fiorelli, F. F. Ferraro, R. M. Milione, R. S. Scarumuzzi, P. I. Imitazione, L. M. Marulli, A. O. Orsini, M. S. Santini
Anaesthesia and Intensive Care, 2016 - Bronchoscopic treatment of complex persistent air leaks with endobronchial one-way valves
Alfonso Fiorelli, Saveria Costanzo, Emanuele Carelli, Emilio Di Costanzo, Mario Santini
General Thoracic and Cardiovascular Surgery, 2016 - Matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in diagnosis of pleural effusion of malignant origin
Alfonso Fiorelli, Serena Ricci, Antonia Feola, Antonio Mazzella, Luigi D'Angelo, Mario Santini, Marina Di Domenico, Angelina Di Carlo
Interactive Cardiovascular and Thoracic Surgery, 2016 - Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors
Rosaria I Staiano, Stefania Loffredo, Francesco Borriello, Fabio Arturo Iannotti, Fabiana Piscitelli, Pierangelo Orlando, Agnese Secondo, Francescopaolo Granata, Maria Teresa Lepore, Alfonso Fiorelli, Gilda Varricchi, Mario Santini, Massimo Triggiani, Vincenzo Di Marzo, Gianni Marone
Journal of Leukocyte Biology, 2016 - Spontaneous pneumothorax associated with talc pulmonary granulomatosis after cocaine inhalation
Alfonso Fiorelli, Marina Accardo, Francesco Rossi, Mario Santini
General Thoracic and Cardiovascular Surgery, 2016 - Spontaneous pneumothorax and cocaine use
Alfonso Fiorelli, Marina Accardo, Mario Santini
Archivos De Bronconeumologia, 2016 - Management of postoperative pain as part of a successful multidisciplinary lung volume reduction surgery programme
Alfonso Fiorelli, Mario Polverino, Mario Santini
European Journal of Cardio Thoracic Surgery, 2016 - Extrapleural pneumonectomy for malignant pleural mesothelioma: A novel mini-invasive technique
Francesco Paolo Caronia, Alfonso Fioretti, Mario Santini, Ettore Arrigo
Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery, 2016 - Erratum: A comparative analysis of Pancoast tumour resection performed via video-assisted thoracic surgery versus standard open approaches (Interactive Cardiovascular and Thoracic Surgery (2014) 19:3 (426-435))
Francesco Paolo Caronia, Alfonso Fiorelli, Enrico Ruffini, Maurizio Nicolosi, Mario Santini, Attilio Ignazio Lo Monte
Interactive Cardiovascular and Thoracic Surgery, 2016 - Efficacy of wound analgesia for controlling post-thoracotomy pain: A randomized double-blind study
Alfonso Fiorelli, Anna Cecilia Izzo, Elisabetta Maria Frongillo, Assunta Del Prete, Giovanni Liguori, Emilio Di Costanzo, Giovanni Vicidomini, Mario Santini
European Journal of Cardio Thoracic Surgery, 2016 - Erratum:Is pre-emptive administration of ketamine a significant adjunction to intravenous morphine analgesia for controlling postoperative pain? A randomized, double-blind, placebo-controlled clinical trial (Interactive Cardiovascular and Thoracic Surgery (2015) 21:3 (284-290))
Alfonso Fiorelli, Antonio Mazzella, Beatrice Passavanti, Pasquale Sansone, Paolo Chiodini, Mario Iannotti, Caterina Aurilio, Mario Santini, Maria Caterina Pace
Interactive Cardiovascular and Thoracic Surgery, 2016 - Descending necrotizing mediastinitis in the elderly patients
Antonio Mazzella, Mario Santagata, Atirge Cecere, Ettore La Mart, Alfonso Fiorelli, Gianpaolo Tartaro, Domenico Tafuri, Domenico Testa, Edoardo Grella, Fabio Perrotta, Andrea Bianco, Gennaro Mazzarella, Mario Santini
Open Medicine Poland, 2016 - Large tracheobronchial fistula due to esophageal stent migration: Let it be!
Alfonso Fiorelli, Giuseppe Esposito, Ilaria Pedicelli, Alfonso Reginelli, Pasquale Esposito, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2015 - SMO gene amplification and activation of the hedgehog pathway as novel mechanisms of resistance to anti-epidermal growth factor receptor drugs in human lung cancer
Carminia Maria Della Corte, Claudio Bellevicine, Giovanni Vicidomini, Donata Vitagliano, Umberto Malapelle, Marina Accardo, Alessio Fabozzi, Alfonso Fiorelli, Morena Fasano, Federica Papaccio, Erika Martinelli, Teresa Troiani, Giancarlo Troncone, Mario Santini, Roberto Bianco, Fortunato Ciardiello, Floriana Morgillo
Clinical Cancer Research, 2015 - Bronchopleural fistula closed with cellulose patch and fibrin glue
Alfonso Fiorelli, Elisabetta Frongillo, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2015 - EReply. Is the pre-emptive administration of ketamine able to prevent chronic post-thoracotomy pain?
Alfonso Fiorelli, Antonio Mazzella, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2015 - Is pre-emptive administration of ketamine a significant adjunction to intravenous morphine analgesia for controlling postoperative pain? A randomized, double-blind, placebo-controlled clinical trial
Alfonso Fiorelli, Antonio Mazzella, Beatrice Passavanti, Pasquale Sansone, Paolo Chiodini, Mario Iannotti, Caterina Aurilio, Mario Santini, Maria Caterina Pace
Interactive Cardiovascular and Thoracic Surgery, 2015 - Two different serum MiRNA signatures correlate with the clinical outcome and histological subtype in pleural malignant mesothelioma patients
Monica Lamberti, Rosanna Capasso, Angela Lombardi, Marina Di Domenico, Alfonso Fiorelli, Antonia Feola, Alessandra F. Perna, Mario Santini, Michele Caraglia, Diego Ingrosso
Plos One, 2015 - Lung adenocarcinoma and its thyroid metastasis characterized on fine-needle aspirates by cytomorphology, immunocytochemistry, and next-generation sequencing
Claudio Bellevicine, Elena Vigliar, Umberto Malapelle, Emanuele Carelli, Alfonso Fiorelli, Giovanni Vicidomini, Salvatore Cappabianca, Mario Santini, Giancarlo Troncone
Diagnostic Cytopathology, 2015 - The feasibility of LigaSure to create intestinal anastomosis: Results of Ex vivo study
Mario Santini, Alfonso Fiorelli, Gaetana Messina, Antonio Mazzella, Marina Accardo
Surgical Innovation, 2015 - Circulating tumor cells in diagnosing lung cancer: Clinical and morphologic analysis
Alfonso Fiorelli, Marina Accardo, Emanuele Carelli, Denise Angioletti, Mario Santini, Marina Di Domenico
Annals of Thoracic Surgery, 2015 - Tracheal ring fracture secondary to percutaneous tracheostomy: Is tracheal flaccidity a risk factor?
Fausto Ferraro, Raffaele Marfella, Marianna Esposito, Jole Petruzzi, Annarita Torino, Anna d’Elia, Mario Santini, Alfonso Fiorelli
Journal of Cardiothoracic and Vascular Anesthesia, 2015 - Is a vessel-sealing system useful for resection of anterior mediastinal mass?
Alfonso Fiorelli, Giovanni Vicidomini, Gaetana Messina, Marina Accardo, Mario Santini
Thoracic and Cardiovascular Surgeon, 2015 - The early detection of lung cancer during follow-up of patients undergoing endobronchial one-way valve treatment for Emphysema
Alfonso Fiorelli, Saveria Costanzo, Emilio di Costanzo, Mario Santini
Archivos De Bronconeumologia, 2015 - Resection of costal exostosis using piezosurgery associated with uniportal video-assisted thoracoscopy
Mario Santini, Alfonso Fiorelli, Mario Santagata, Gian Paolo Tartaro
Annals of Thoracic Surgery, 2015 - A home-made animal model in comparison with a standard manikin for teaching percutaneous dilatational tracheostomy
Alfonso Fiorelli, Emanuele Carelli, Denise Angioletti, Annarita Orsini, Anna D'Elia, Annarita Torino, Mario Santini, Fausto Ferraro
Interactive Cardiovascular and Thoracic Surgery, 2015 - Incidence, Risk Factors, and Analysis of Survival of Unexpected N2 Disease in Stage i Non-Small Cell Lung Cancer
Alfonso Fiorelli, Dariusz Sagan, Lukasz Mackiewicz, Lucio Cagini, Elisa Scarnecchia, Paolo Chiodini, Francesco Caronia, Francesco Puma, Mark Ragusa, Mario Santini
Thoracic and Cardiovascular Surgeon, 2015 - Uniportal bilateral video-assisted thoracoscopic extended thymectomy for myasthenia gravis: A case report
Francesco Paolo Caronia, Alfonso Fiorelli, Mario Santini, Salvatore Cottone
Journal of Thoracic and Cardiovascular Surgery, 2015 - Mediastinal sarcoid-like reaction after colon adenocarcinoma resection
Alfonso Fiorelli, Marina Accardo, Michele Orditura, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2015 - Interlobar fixation using TachoSil®: A novel technique
Alfonso Fiorelli, Roberto Scaramuzzi, Saveria Costanzo, Antonio Volpicelli, Mario Santini
Translational Lung Cancer Research, 2015 - The use of an electrothermal bipolar tissue sealing system in the management of lung hydatid disease
Mario Santini, Alfonso Fiorelli, Roberta Milione, Giovanni Vicidomini, Marina Accardo
Interactive Cardiovascular and Thoracic Surgery, 2014 - The Influence of Body Mass Index and Weight Loss on Outcome of Elderly Patients Undergoing Lung Cancer Resection
Alfonso Fiorelli, Giovanni Vicidomini, Antonio Mazzella, Gaetana Messina, Roberta Milione, Vincenzo Di Crescenzo, Mario Santini
Thoracic and Cardiovascular Surgeon, 2014 - Isolated mediastinal amyloidosis mimicking a neoplastic lesion
Alfonso Fiorelli, Marina Accardo, Giuseppe Ciancia, Guido Pettinato, Mario Santini
General Thoracic and Cardiovascular Surgery, 2014 - A comparative analysis of Pancoast tumour resection performed via video-assisted thoracic surgery versus standard open approaches
Francesco Paolo Caronia, Alfonso Fiorelli, Enrico Ruffini, Maurizio Nicolosi, Mario Santini, Attilio Ignazio Lo Monte
Interactive Cardiovascular and Thoracic Surgery, 2014 - Does cannabis smoking predispose to lung bulla formation?
Alfonso Fiorelli, Marina Accardo, Giovanni Vicidomini, Gaetana Messina, Paolo Laperuta, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2014 - Combined transbronchial needle aspiration and 99m Tc-2-methoxy-isobutyl-isonitrile single photon emission computed tomography for diagnosing enlarged mediastinal lymph nodes
Alfonso Fiorelli, Pierfrancesco Rambaldi, Giovanni Vicidomini, Umberto di Serio, Marina Accardo, Antonio Rotondo, Mario Santini
Archivos De Bronconeumologia, 2014 - A simple technique to control placement of Dumon stent in subglottic tracheal stenosis
Alfonso Fiorelli, Salvatore Mazzone, Vincenzo Giuseppe Di Crescenzo, Giuseppe Costa, Assunta Del Prete, Giovanni Vicidomini, Adriano Mazzone, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2014 - Quantitative assessment of emphysematous parenchyma using multidetector-row computed tomography in patients scheduled for endobronchial treatment with one-way valves
Alfonso Fiorelli, Mario Petrillo, Giovanni Vicidomini, Vincenzo Giuseppe Di Crescenzo, Elisabetta Frongillo, Alberto De Felice, Antonio Rotondo, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2014 - Antineoplastic activity of povidone-iodine on different mesothelioma cell lines: Results of in vitro study
A. Fiorelli, F. Pentimalli, V. D'Urso, D. Di Marzo, I. M. Forte, A. Giordano, M. Di Domenico, M. Accardo, U. Di Serio, M. Santini
European Journal of Cardio Thoracic Surgery, 2014 - The digital AcuBlade laser system to remove huge vocal fold granulations following subglottic airway stent
Alfonso Fiorelli, Salvatore Mazzone, Adriano Mazzone, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2013 - In lung cancer patients where a malignant pleural effusion is found at operation could resection ever still be justified?
A. Fiorelli, M. Santini
Interactive Cardiovascular and Thoracic Surgery, 2013 - The use of the LigaSure device and the Stapler in closure of the small bowel: A comparative ex vivo study
Mario Santini, Alfonso Fiorelli, Gaetana Messina, Paolo Laperuta, Antonio Mazzella, Marina Accardo
Surgery Today, 2013 - The value of matrix metalloproteinase-9 and vascular endothelial growth factor receptor 1 pathway in diagnosing indeterminate pleural effusion
Alfonso Fiorelli, Floriana Morgillo, Morena Fasano, Giovanni Vicidomini, Vincenzo Giuseppe Di Crescenzo, Marina Di Domenico, Marina Accardo, Mario Santini
Interactive Cardiovascular and Thoracic Surgery, 2013 - Tracheobronchial Amyloidosis Treated by Endobronchial Laser Resection and Self Expanding Y Stent
Alfonso Fiorelli, Marina Accardo, Giovanni Galluccio, Mario Santini
Archivos De Bronconeumologia, 2013 - LigaSure meets endobronchial valve in a case of lung cancer with pneumoconiosis
Alfonso Fiorelli, Marina Accardo, Giovanni Vicidomini, Mario Santini
Translational Lung Cancer Research, 2013 - The effects of lung resection on physiological motor activity of the oesophagus
Alfonso Fiorelli, Giovanni Vicidomini, Roberta Milione, Roberto Grassi, Antonio Rotondo, Mario Santini
European Journal of Cardio Thoracic Surgery, 2013 - Cardiac and skeletal muscle expression of mutant β-myosin heavy chains, degree of functional impairment and phenotypic heterogeneity in hypertrophic cardiomyopathy
Marina Di Domenico, Rita Casadonte, Pietroantonio Ricci, Mario Santini, Giacomo Frati, Antonietta Rizzo, Caterina Romano Carratelli, Monica Lamberti, Elvira Parrotta, Barbara Quaresima, Concetta M. Faniello, Francesco Costanzo, Giovanni Cuda
Journal of Cellular Physiology, 2012 - Acute life-threatening airway obstruction with pseudomembrane formation after percutaneous dilational tracheostomy
Anaesthesia and Intensive Care, 2012 - T2-T3 sympathectomy versus sympathicotomy for essential palmar hyperhidrosis: Comparison of effects on cardio-respiratory function
A. Fiorelli, A. D'Aponte, R. Canonico, A. Palladino, G. Vicidomini, F. Limongelli, M. Santini
European Journal of Cardio Thoracic Surgery, 2012 - Recurrent spontaneous pneumomediastinum: A rare but possible event!
Zongfei Wang, Chu Pei, Lunchao Ma, Daoyuan Wang, Jiangfen Zhou, et al.
Journal of Thoracic Disease, 2012 - Malignant transformation of bronchogenic cyst revealed by 99mTc-MIBI-SPECT
Alfonso Fiorelli, Pierfrancesco Rambaldi, Marina Accardo, Mario Santini
Asian Cardiovascular and Thoracic Annals, 2012 - Reply to Anile et al.
A. Fiorelli, G. Vicidomini, G. Messina, M. Santini
European Journal of Cardio Thoracic Surgery, 2012 - Control of post-thoracotomy pain by transcutaneous electrical nerve stimulation: Effect on serum cytokine levels, visual analogue scale,pulmonary function and medication
A. Fiorelli, F. Morgillo, R. Milione, M. C. Pace, M. B. Passavanti, P. Laperuta, C. Aurilio, M. Santini
European Journal of Cardio Thoracic Surgery, 2012 - Correlation between matrix metalloproteinase 9 and 18F-2-fluoro-2-deoxyglucose-positron emission tomography as diagnostic markers of lung cancer
A. Fiorelli, A. Rizzo, G. Messina, A. Izzo, G. Vicidomini, G. Pannone, M. Santini, M. Di Domenico
European Journal of Cardio Thoracic Surgery, 2012 - An unpredicted case of tracheal necrosis following thyroidectomy
Annali Italiani Di Chirurgia, 2012 - Tracheal necrosis, oesophageal fistula: Unusual complications of thyroidectomy. Report of two case and literature review
Annali Italiani Di Chirurgia, 2012 - Bilateral lung lesions: When the eyes deceive the brain!
Annali Italiani Di Chirurgia, 2012 - Spontaneous pneumothorax after chemotherapy for sarcoma with lung metastases: Case report and consideration of pathogenesis
Alfonso Fiorelli, Giovanni Vicidomini, Filomena Napolitano, Mario Santini
Journal of Thoracic Disease, 2011 - Metastasis from transitional cell carcinoma of urinary bladder as cystic pulm onary lesion
Alfonso Fiorelli, Giovanni Vicidomini, Gaetana Messina, Mario Santini
Journal of Thoracic Disease, 2011 - Endobronchial treatment of giant emphysematous bullae with one-way valves: A new approach for surgically unfit patients
Mario Santini, Alfonso Fiorelli, Giovanni Vicidomini, Vincenzo Giuseppe Di Crescenzo, Gaetana Messina, Paolo Laperuta
European Journal of Cardio Thoracic Surgery, 2011 - Interplay between steroid receptors and neoplastic progression in sarcoma tumors
A. Fiorelli, C. Ricciardi, G. Pannone, A. Santoro, P. Bufo, M. Santini, R. Serpico, R. Rullo, G.M. Pierantoni, M. Di Domenico
Journal of Cellular Physiology, 2011 - Spontaneous expectoration of an obstructive fibrinous tracheal pseudomembrane after tracheal intubation
Alfonso Fiorelli, Giovanni Vicidomini, Gaetana Messina, Mario Santini
European Journal of Cardio Thoracic Surgery, 2011 - The role of Tc-99m-2-Methoxy-Isobutyl-Isonitrile Single Photon Emission Computed Tomography in visualizing anterior mediastinal tumor and differentiating histologic type of thymoma
Alfonso Fiorelli, Giovanni Vicidomini, Paolo Laperuta, Pierfrancesco Rambaldi, Luigi Mansi, Antonio Rotondo, Mario Santini
European Journal of Cardio Thoracic Surgery, 2011 - Vascular endothelial growth factor in pleural fluid for differential diagnosis of benign and malignant origin and its clinical applications
A. Fiorelli, G. Vicidomini, M. Di Domenico, F. Napolitano, G. Messina, F. Morgillo, F. Ciardiello, M. Santini
Interactive Cardiovascular and Thoracic Surgery, 2011 - Negative-pressure pulmonary edema presented with concomitant spontaneous pneumomediastinum: Moore meets Macklin
A. Fiorelli, S. Brongo, F. D'Andrea, M. Santini
Interactive Cardiovascular and Thoracic Surgery, 2011 - F-18-2-fluoro-2-deoxyglucose positron emission tomography compared to technetium-99m hexakis-2-methoxyisobutyl isonitrile single photon emission chest tomography in the diagnosis of indeterminate lung lesions
Mario Santini, Alfonso Fiorelli, Giovanni Vicidomini, Paolo Laperuta, Luigi Busiello, Pier Francesco Rambaldi, Luigi Mansi, Antonio Rotondo
Respiration, 2010 - A simple device designed to facilitate sternal closure and avoid complications
M. Santini, G. Vicidomini, A. Fiorelli
Thoracic and Cardiovascular Surgeon, 2010 - Iatrogenic Air Leak Successfully Treated by Bronchoscopic Placement of Unidirectional Endobronchial Valves
Mario Santini, Alfonso Fiorelli, Giovanni Vicidomini, Paolo Laperuta, Vincenzo Giuseppe Di Crescenzo
Annals of Thoracic Surgery, 2010 - Impact of positive pleural lavage cytology on survival in patients having lung resection for non-small-cell lung cancer: An international individual patient data meta-analysis
Eric Lim, Rachel E. Clough, Peter Goldstraw, Lyn Edmonds, Keiju Aokage, et al.
Journal of Thoracic and Cardiovascular Surgery, 2010 - Pre-emptive local analgesia in video-assisted thoracic surgery sympathectomy
Alfonso Fiorelli, Giovanni Vicidomini, Paolo Laperuta, Luigi Busiello, Anna Perrone, Filomena Napolitano, Gaetana Messina, Mario Santini
European Journal of Cardio Thoracic Surgery, 2010 - Use of unidirectional endobronchial valves for the treatment of giant emphysematous bulla
Mario Santini, Alfonso Fiorello, Vincenzo Giuseppe Di Crescenzo, Giovanni Vicidomini, Luigi Busiello, Paolo Laperuta
Journal of Thoracic and Cardiovascular Surgery, 2010 - Intrathoracic Extramedullary Haematopoiesis Manifested as a Neoplastic Lesion Within Anterior Mediastinum
Mario Santini, Alfonso Fiorelli, Giovanni Vicidomini, Filomena Napolitano
Annals of Thoracic Surgery, 2009 - Global gene expression profiling of human pleural mesotheliomas: Identification of matrix metalloproteinase 14 (MMP-14) as potential tumour target
Stefania Crispi, Raffaele A. Calogero, Mario Santini, Pasquale Mellone, Bruno Vincenzi, Gennaro Citro, Giovanni Vicidomini, Silvia Fasano, Rosaria Meccariello, Gilda Cobellis, Simona Menegozzo, Riccardo Pierantoni, Francesco Facciolo, Alfonso Baldi, Massimo Menegozzo
Plos One, 2009 - A Surgical Case of Pyothorax-Associated Lymphoma of T-Cell Origin Arising From the Chest Wall in Chronic Empyema
Mario Santini, Alfonso Fiorello, Giovanni Vicidomini, Luigi Busiello, Alfonso Baldi
Annals of Thoracic Surgery, 2009 - The role of technetium-99m hexakis-2-methoxyisobutyl isonitrile in the detection of neoplastic lung lesions
Mario Santini, Alfonso Fiorello, Luigi Mansi, Pier Francesco Rambaldi, Giovanni Vicidomini, Luigi Busiello, Gaetana Messina, Paola Nargi
European Journal of Cardio Thoracic Surgery, 2009 - Pulmonary hernia secondary to limited access for mitral valve surgery and repaired by video thoracoscopic surgery
Mario Santini, Alfonso Fiorello, Giovanni Vicidomini, Luigi Busiello
Interactive Cardiovascular and Thoracic Surgery, 2009 - Lung mast cells are a source of secreted phospholipases A2
Massimo Triggiani, Giorgio Giannattasio, Cecilia Calabrese, Stefania Loffredo, Francescopaolo Granata, Alfonso Fiorello, Mario Santini, Michael H. Gelb, Gianni Marone
Journal of Allergy and Clinical Immunology, 2009 - Expression of the embryonic lethal abnormal vision-like protein HuR in human mesothelioma: Association with cyclooxygenase-2 and prognosis
Daniela Stoppoloni, Irene Cardillo, Alessandra Verdina, Bruno Vincenzi, Simona Menegozzo, Mario Santini, Ada Sacchi, Alfonso Baldi, Rossella Galati
Cancer, 2008 - Marijuana smokers and lung bullae
Alfonso Fiorello, Giovanni Vicidomini, Mario Santini
European Journal of Cardio Thoracic Surgery, 2008 - The serine protease HtrA1 is a novel prognostic factor for human mesothelioma
Alfonso Baldi, Marcella Mottolese, Bruno Vincenzi, Mara Campioni, Pasquale Mellone, Mariapia Di Marino, Vincenzo G di Crescenzo, Paolo Visca, Simona Menegozzo, Enrico P Spugnini, Gennaro Citro, Anna Ceribelli, Alessandra Mirri, Jeremy Chien, Viji Shridhar, Michael Ehrmann, Mario Santini, Francesco Facciolo
Pharmacogenomics, 2008 - The use of LigaSure for preservation of a previous coronary artery bypass graft by using the left internal thoracic artery in a left upper lobectomy
Mario Santini, Alfonso Fiorello, Giovanni Vicidomini, Paolo Laperuta
Journal of Thoracic and Cardiovascular Surgery, 2008 - A home-made device for safe intraoperative aspiration of pulmonary hydatid cysts
M. Santini, A. Fiorello, G. Vicidomini, A. Perrone
Interactive Cardiovascular and Thoracic Surgery, 2008 - Giant solitary fibrous tumors of the pleura: Two case reports
A. Fiorello, G. Vicidomini, M. Santini
Thoracic and Cardiovascular Surgeon, 2007 - Role of diffusing capacity in predicting complications after lung resection for cancer
M. Santini, A. Fiorello, G. Vicidomini, V. Di Crescenzo, P. Laperuta
Thoracic and Cardiovascular Surgeon, 2007 - Unusual case of Boerhaave syndrome, diagnosed late and successfully treated by Abbott's T-tube
Mario Santini, Alfonso Fiorello, Salvatore Cappabianca, Giovanni Vicidomini
Journal of Thoracic and Cardiovascular Surgery, 2007 - An enormous asymptomatic solitary fibrous tumour of the pleura
Alfonso Fiorello, Giovanni Vicidomini, Vincenzo Pastore, Mario Santini
European Journal of Cardio Thoracic Surgery, 2006 - Surgical strategies in cervico-mediastinal goiters
Minerva Chirurgica, 2006 - Use of an electrothermal bipolar tissue sealing system in lung surgery
Mario Santini, Giovanni Vicidomini, Alfonso Baldi, Giuseppe Gallo, Paolo Laperuta, Luigi Busiello, Maria Pia Di Marino, Vincenzo Pastore
European Journal of Cardio Thoracic Surgery, 2006 - Use of a modified endobronchial tube for mechanical ventilation of patients with bronchopleural fistula
Mario Santini, Giovanni Vicidomini, Giovanni La Monica, Vincenzo Pastore
European Journal of Cardio Thoracic Surgery, 2005 - Intraoperative pleural lavage: Is it a valid prognostic factor in lung cancer?
Giovanni Vicidomini, Mario Santini, Alfonso Fiorello, Vincenzo Parascandolo, Barbara Calabrò, Vincenzo Pastore
Annals of Thoracic Surgery, 2005 - Intraoperative pleural lavage cytology should not influence decision for radical surgery in nonsmall cell lung cancer [4] (multiple letters)
C.S. Pramesh, Rajesh C. Mistry, Jaiprakash Agarwal
Annals of Thoracic Surgery, 2005 - Early biomarkers of pleural malignant mesothelioma in workers past exposed to asbestos: Proposal of a survey
Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2004 - Mediastinal hibernoma: A case report
A Baldi, M Santini, P Mellone, V Esposito, A M Groeger, M Caputi, F Baldi
Journal of Clinical Pathology, 2004 - Primary cardiac T-cell lymphoma
Riccardo Giunta, Ranieri G. Cravero, Gianluca Granata, Ausilia Sellitto, Ciro Romano, Umberto De Fanis, Giampiero Foccillo, Cleofina De Capite, Mario Santini, Luigi Rossiello, Raffaele Rossiello, Giacomo Lucivero
Annals of Hematology, 2004 - Prognostic significance of cyclooxygenase-2 (COX-2) and expression of cell cycle inhibitors p21 and p27 in human pleural malignant mesothelioma
A Baldi
Thorax, 2004 - Retroperitoneal pleomorphic liposarcoma. A case of survival after ten years
Recenti Progressi in Medicina, 2004 - Analysis of cell cycle regulator proteins in non-small cell lung cancer
V Esposito, A Baldi, G Tonini, B Vincenzi, M Santini, V Ambrogi, T C Mineo, P Persichetti, G Liuzzi, V Montesarchio, E Wolner, F Baldi, A M Groeger
Journal of Clinical Pathology, 2004 - Analysis of Fas (Apo-1/CD95) Expression in Non-small Cell Lung Cancer
Anticancer Research, 2003 - Expression of p21 in SV40 large T antigen positive human pleural mesothelioma: Relationship with survival
A Baldi
Thorax, 2002 - Lung carcinoma. An unusual case of survival
Recenti Progressi in Medicina, 2002 - Papillary pneumocytoma of the lung simulating adenoma
In Vivo, 2002 - Solitary muscle metastasis from lung carcinoma
Journal of Cardiovascular Surgery, 2001 - Gemcitabine and small cell lung cancer
Michele Della Vittoria Scarpati, Giovanni Vicidomini, Mario Santini
Lung Cancer, 2001 - Role of the surgeon in the treatment of small cell lung carcinoma
Minerva Endocrinologica, 2001 - Role of radio-guided surgery with 111In-octreotide in the treatment of thoracic neoplasms
Minerva Endocrinologica, 2001 - Pleural mesothelioma. A case report
Recenti Progressi in Medicina, 1999 - Relapsing pneumothorax due to Ascaris lumbricoides larvae
Monaldi Archives for Chest Disease, 1999 - Intraoperative detection of lung cancer by octreotide labeled to Indium- 111
Vincenzo Pastore, Eugenio Di Lieto, Luigi Mansi, Pier Francesco Rambaldi, Mario Santini, Rosario Mancusi
Seminars in Surgical Oncology, 1998 - Congenital cystic adenomatoid malformation of the lung in an adult
Minerva Chirurgica, 1997 - Staging and surgical therapy of lung cancer
Lotta Contro La Tuberculosi E Le Malattie Polmonari Sociali, 1995
