Begum fauziyah

@uin-malang.ac.id



              

https://researchid.co/begumfauziyah
11

Scopus Publications

275

Scholar Citations

9

Scholar h-index

6

Scholar i10-index

Scopus Publications

  • Evaluation of Self Nanoemulsifying Drug Delivery System from Qusthul Hindi (Saussurea lappa) Extract: In vitro Release and Absorption Assessment
    R. Annisa, Roihatul Muti’ah, Avin Ainur Fitrianingsih, B. Fauziyah, Nabila Rahmadani and Wirda Anggraini

    This study aimed to determine the release and absorption flux values of qusthul Hindi (Saussurea lappa) self nanoemulsifying drug delivery system using the template formula for the optimal D-optimal design approach. The method is emulsification. The in vitro release test used the dialysis bag method. The absorption test was carried out through the intestinal membrane using the Crane and Wilson tube method. The levels released and absorbed were measured using a UV-Vis Spectrophotometer. The results showed that in vitro release and absorption values in SNEDDS were higher than the qusthul Hindi (Saussurea lappa) extract solution in both artificial intestinal fluid media at pH 6.8 ± 0.05 and artificial gastric fluid at pH 1.2 ± 0.05. The analysis found a significant difference in flux for both release (p=0.02) and absorption (p=0.01). The SNEDDS formula provided in vitro release flux results that were 4.20 times higher in AGF media and 5.62 times higher in AIF media compared to the extract solution. In vitroabsorption results also indicated a 4.02 times increase in AGF media and 3.32 times higher in AIF compared to the extract solution. The selected formulas using miglyol 812, Tween 80, and Polyethylenflycol 400 components at concentrations of 2.13%, 5.81%, and 2.06% can be used for SNEDDS formulations of qusthul Hindi (Saussurea lappa). These formulations showed superior in vitro release and absorption results compared to the extract solution in both AIF media at pH 6.8 ± 0.05 and AGF media at pH 1.2 ± 0.05.

  • Network Pharmacology and Component Analysis Integrated Study to Uncovers the Molecular Mechanisms of Lansium parasiticum Bark Extract in Colon Cancer Treatment
    Roihatul Mutiah, Malich Septi Diajeng Briliana, Ananda Rizkia Azizah Ahmad, Begum Fauziyah, Nandana Adyuta Janaloka, and Arief Suryadinata
    ARTS Publishing
    Side effects and risk of resistance are common consequences of colon cancer treatment based on chemotherapy. The medicinal plant originating in Indonesia, Lansium parasiticum bark extract (LPBE), has not been studied much. The purpose of this study is to identify the compounds present in LPBE and explain how the molecular mechanisms of the composite inhibit colon cancer cells. LC-MS/MS Liquid Chromatography Tandem Mass Spectrophotometry has been used to identify compounds in LPBE. The ADMET program is used to determine absorption profiles and bioavailability per oral. The tissue pharmacology approach uses Cytoscape 3.9.1, GeneCards, Disgenet, STRING 2.0.0, SRplot, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway to predict the molecular anti-cancer mechanisms of these compounds. In vitro validation using PyRx Autodock Vina 9.0 and Biovia Discovery Studio with BAX (PDB ID:2YXJ), BCL2 (P DB ID:2W3L) and STAT3 receptors (PDB ID:6NJS). A total of 17 active compounds were identified through LC-MS/MS. The moronic acid compound showed the highest levels of 14.29% followed by 4-Morpholineacetic Acid 12.2% and ursolic aldehyde 8.37%. Pharmacological network analysis showed that the compounder works on the EGFR tyrosine kinase resistance path by targeting the BCL2, BAX, STAT3 genes. The results of the in silico validation support the results of tissue pharmacology findings. Ursolic aldehyde, and Moronic acid showed a higher affinity to the three receptors. Therefore, Lansium parasiticum bark extract (LPBE) is recommended for further study as a candidate anti-cancer drug both in vitro and in vivo.

  • Comparison of Microwave and Oven Extraction Methods on the Quality of Pork, Beef and Duck Gelatine
    Begum Fauziyah, Dyah Fatimatussholichah, and Aldila Syarifah
    Egypts Presidential Specialized Council for Education and Scientific Research

  • The effect of additional sucrose on the value of tensile strength and elongation of chicken legs gelatin film
    B. Fauziyah, Dyah Fatimatussholichah, Aldila Syarifah and Burhan Ma’arif

    Gelatin is a clear, flavorless, and colorless biopolymer formed by the denaturation of collagen protein in animal tissues. Gelatin is an important ingredient in the manufacture of capsule shell films. The tensile strength and elongation values of gelatin film indicate its quality. Sucrose is one of the ingredients that can affect the tensile strength and elongation of the gelatin film. To determine the effect of adding sucrose on the tensile strength and elongation of the chicken leg skin gelatin film. To extract the gelatin, clean, sliced chicken leg skin was freeze-dried, ground into powder, and extracted. The characteristics of chicken skin gelatin were measured using Fourier-transform infrared, and the data were read in the 4000–400 cm − 1 range for 32 scans. Pouring the solution into a mold, flattening it, and drying it at 40°C results in a film that has been tested for tensile strength and elongation. Gelatin films with a 30% sucrose addition had the best tensile strength and elongation values, with a tensile strength of 3.03 MPa and an elongation of 152.02%. Sucrose alters the tensile strength and elongation of chicken leg gelatin film. 30% sucrose provides better tensile and elongation strength.

  • Analysis of Bioactive Compounds in Nabeez Water
    Begum Fauziyah, Asna Defi Batrisyia, Alif Firman Firdausy, Burhan Ma’arif, and Siti Maimunah
    Oriental Scientific Publishing Company
    Dates (Phoenix dactylifera L.) are a unique fruit because they have many health benefits. Ajwa dates are one of the dates that many people are interested in for ingestion. Making date-infused water or nabeez water is one technique to ingest dates as exemplified by the Prophet SAW and is believed to have many benefits for digestion. As a result, there has never been any research on the analysis of active compounds from nabeez water, particularly Ajwa dates themselves, so the goal of this study was to determine the content of active compounds in nabeez water as well as the total content based on qualitative and quantitative analysis. The nabeez water from dates was tested qualitatively and quantitatively using phytochemical tests and UV-Visible Spectrophotometry. The results show that the nabeez water contains active ingredients of flavonoids, saponins, alkaloids, and tannins, according to qualitative analytical results. The quantitative analysis showed that nabeez water has a total concentration of flavonoid compounds of 5.749 g/mL and a concentration of tannin compounds of 52.934 g/mL.


  • Runt-Related Transcription Factor 2 (Runx2) Measurement in Phytoestrogen-Induced Bone: A Comparison of Western Blot and Immunohistochemistry Methods
    Burhan Ma’arif, Fariza Amanatul Sholihah, Anisah Mahardiani, Begum Fauziyah, Denis Mery Mirza, and Mangestuti Agil
    Oriental Scientific Publishing Company
    Estrogen deficiency can contribute to osteoporosis in postmenopausal women. Phytoestrogens are becoming more widely recognized as potential estrogen replacement therapy. The administration of phytoestrogens can cause bone formation, which is marked by an increase in Runx2 expression in osteoblast cells and can be seen using western blot and immunohistochemistry approaches. This review aimed to compare the detection methods of Runx2 in phytoestrogen-induced bone tissue using western blots and immunohistochemistry. Selectivity, sensitivity, processing time, and cost-effectiveness were the parameters that were compared. This review was done by identifying articles in several databases (Google Scholar, PubMed, and Science Direct). The process of selecting the articles used the PRISMA guidelines to create a flowchart with inclusion and exclusion study criteria. Meta-synthesis was done to analyze, identify, and interpret all of the data in the articles systematically. 70 articles in total were obtained from the selection process, with 21 articles being relevant to the topic. The result shows that the selectivity and sensitivity of western blot for detecting Runx2 on tissue were 93.5–100%, respectively, whereas immunohistochemistry selectivity and sensitivity were 45–99.5%, respectively. Compared to immunohistochemistry, western blot can save up to 57.26%. Immunohistochemistry takes 46 hours to process, while Western blot takes 25 hours and 20 minutes. In comparison to immunohistochemistry, the western blot is more selective, sensitive, rapid and affordable for detecting Runx2 in bone tissue.

  • The effect of acid variation on physical and chemical characteristics of cellulose isolated from Saccharum officinarum L. Bagasse
    B Fauziyah, M Yuwono, and Isnaeni
    IOP Publishing
    Abstract Saccharum officinarum L. bagasse is waste from sugarcane plants contains lignin, hemicellulose, cellulose and wax compounds. Isolation of cellulose from sugarcane can be done by acid hydrolysis of sugarcane waste and delignification with Sodium Hydroxide (NaOH). The objectives of this research were to study the effect of acid type and concentration on the physical and chemical characteristics of cellulose isolated from sugarcane bagasse. The acid variation that used were nitric acid: sulphuric acid; nitric acid; hydrochloric acid and sulphuric acid: hydrochloric acid in 1:1; 2:1 and 3:1 in the variation of concentration for each combination. Cellulose characteristics observed were color, shape and powder properties such as Hausner Ratio, Carr’s index, Angle of Repose and functional group analysis of cellulose using FTIR (Fourier Transform Infrared). The cellulose that isolated from sugarcane bagasse with HNO3: H2SO and HNO3: HCl were matched in white powder form with standard cellulose. Cellulose color that obtained with other acids were cream in fiber form. The results showed that the hydrolysis process of cellulose with nitric acid was more effective than sulfuric acid and hydrochloric acid. Standard cellulose FTIR spectra showed that delignification process was success and cellulose obtained from sugarcane bagasse. Sugarcane bagasse cellulose samples that isolated with nitric acid: hydrochloric acid (2:1) was the largest in percentage of cellulose (44.143%) and showed in line peaks with standard cellulose. Bulk Densities, Tapped Densities, Hausner Ratio, Carr’s index and Angle of Repose values of sugarcane bagasse cellulose isolated in sequence were 0.05; 0.07; excellent; 26.6; good.

  • Tensile strength and elongation analysis on nano cellulose Film Isolated from Sugarcane Bagasse
    M Yuwono, B Fauziyah, Isnaeni, and A Nisak
    IOP Publishing
    Abstract Nano cellulose was successfully isolated from sugarcane bagasse through sulphuric acid hydrolysis of sugarcane bagasse cellulose. Physically, Nano cellulose was transparent and broken white. The crystallinity index of sugarcane bagasse nano cellulose was 80.72%. The particle size of sugarcane bagasse nano cellulose was 225 nm. Delignification process in isolation was successfully showed by releasing peaks in 1239.3 and 1507.7. It show C-O-C vibration of aryl group in lignin and C=C aromatic ring in lignin respectively. Sugarcane bagasse cellulose shows peaks at 1720.2 that represent COOH and hemicellulose carboxylic groups, while the others were not found. The crystallinity index of Nano cellulose was 42.65%. Nano cellulose film prepared in several concentrations (3%, 6%, and 9%). Nano cellulose film also prepared with adding HPMC 2%. Nano cellulose film prepared in 9% concentration was too strict and broken easily. The tensile strength and elongation of Nano cellulose film that prepared in 3% + HPMC 2% and 6% + HPMC 2% were 3.177 Mpa, 10.93% and 3.315 Mpa dan 3.7% respectively.

  • The optimization of eluent chromatography thin layer 2-D for the purification of isolat alkaloid of pulai having potention as anti-toxoplasma


  • A method in urea sensor fabrication based immobilization diacetylmonoxime-thiosemicarbazide onto silica paper


RECENT SCHOLAR PUBLICATIONS

  • Evaluation of Self Nanoemulsifying Drug Delivery System from Qusthul Hindi (Saussurea lappa) Extract: In vitro Release and Absorption Assessment
    R Annisa, R Muti’ah, AA Fitrianingsih, B Fauziyah, N Rahmadani, ...
    Biomedical and Pharmacology Journal 17 (4), 2329-2339 2024

  • Network Pharmacology and Component Analysis Integrated Study to Uncovers the Molecular Mechanisms of Lansium parasiticum Bark Extract in Colon Cancer Treatment
    R Mutiah, MSD Briliana, ARA Ahmad, B Fauziyah, NA Janaloka, ...
    Science and Technology Indonesia 9 (2), 314-324 2024

  • Optimalisasi manfaat limbah ampas tebu dalam formulasi transdermal patch anti nyeri (sertifikat hak cipta)
    B Fauziyah, A Wafi
     2024

  • Sistem integrasi LPH Halal Center UIN Maulana Malik Ibrahim Malang dengan SiHalal BPJH berbasis web (sertifikat hak cipta)
    B Fauziyah, ATW Almais, PD Fitriasari, TM Lestari
     2023

  • Comparison of Microwave and Oven Extraction Methods on The Quality Of Pork, Beef And Duck Gelatine
    B Fauziyah, D Fatimatussholichah, AR Syarifah
    Egyptian Journal of Chemistry 66 (4), 189-195 2023

  • Pendampingan penguatan moderasi beragama di Australia
    B Fauziyah, N Solikin
     2023

  • Formulation of Silver Nanoparticle Mouthwash and Testing of Antibacterial Activity Against Staphylococcus aureus
    R Annisa, B Fauziyah, DS Megawati, F Zahrah
    Journal of Tropical Pharmacy and Chemistry 7 (2), 52-58 2023

  • The effect of additional sucrose on the value of tensile strength and elongation of chicken legs gelatin film
    B Fauziyah, D Fatimatussholichah, AR Syarifah, B Ma'arif
    Journal of Advanced Pharmaceutical Technology & Research 14 (1), 56-61 2023

  • Analysis of Bioactive Compounds in Nabeez Water
    B Fauziyah, AD Batrisyia, AF Firdausy, B Ma’arif, S Maimunah
    Biomedical and Pharmacology Journal 15 (3), 1721-1728 2022

  • Sistem informasi manajemen riset unggulan fakultas berbasis web
    B Fauziyah, Y Yueniwati, S Maimunah, TM Lestari
    JATISI (Jurnal Teknik Informatika Dan Sistem Informasi) 9 (3), 2351-2362 2022

  • Isolation and characterization of sugarcane (Saccharum officinarum l.) bagasse cellulose hydrolyzed with acid variation
    B Fauziyah, M Yuwono, I Isnaeni, N Nahdhia, F Sholihah
    Tropical Journal of Natural Product Research 6 (6), 856-862 2022

  • Systematic Review: Anti-Osteoporosis Potential Activities Of Phytoestrogen Compounds In Chrysophyllum cainito L., Elaeis guineensis Jacq., Lannea acida Rich., Marsilea crenata
    B Ma'arif, S Suryanto, FA Muslikh, A Suryadinata, B Fauziyah
    Jurnal Farmasi Sains dan Komunitas (JFSK) 19 (1), 41-52 2022

  • Runt-related transcription factor 2 (Runx2) measurement in phytoestrogen-induced bone: a comparison of western blot and immunohistochemistry methods
    B Ma'arif, FA Sholihah, A Mahardiani, B Fauziyah, DM Mirza, M Agil
    Biomedical and Pharmacology Journal 15 (2), 1039-1052 2022

  • Studi in silico penghambatan aktivasi TLR2 ekstrak etanol daun semanggi (Marsilea crenata Presl.)
    B Ma'arif, DAP Fihuda, FA Muslikh, S Syarifuddin, B Fauziyah, DP Sari, ...
    Jurnal Tumbuhan Obat Indonesia 15 (1), 31-40 2022

  • Prediction of compounds from 96% Ethanol Extract of Marsilea crenata Presl. Leaves in increasing estrogen receptor-α activation
    B Ma'arif, FA Muslikh, DAP Fihuda, S Syarifuddin, B Fauziyah
     2021

  • Effect of addition virgin coconut oil (VCO) on physical stability and SPF value of sunscreen cream combination of zinc oxide and titanium dioxide
    BC Jayati, R Annisa, AF Firdausy, DS Megawati, B Fauziyah
     2021

  • Analysis of Powder Properties and Pharmacopeial Spesifications of Bagasse Cellulose Isolated from Saccharum Officinarum L in Indonesia.
    B Fauziyah, M Yuwono
    Indian Journal of Forensic Medicine & Toxicology 15 (3) 2021

  • Ensiklopedia Ilmu Farmasi: mengenal dunia pendidikan kefarmasian mulai dari ilmu dasar hingga terapan
    A Hakim, YYA Indrawijaya, R Mutiah, B Ma'arif, T Jati Dharma Dewi, ...
    UIN Maliki Press, Malang. Chrysanthemum cinerariifolium (Trev.) Vis dengan 2021

  • Potensi ampas tebu di bidang farmasi
    B Fauziyah
    Literasi Nusantara 2021

  • Pengembangan Bahan Baku Selulosa Dan Nanoselulosa Ampas Tebu (Saccharum Officinarum L.) Sebagai Upaya Mendukung Kemandirian Produksi Bahan Baku Sediaan Farmasi Halal
    B Fauziyah
    UNIVERSITAS AIRLANGGA 2021

MOST CITED SCHOLAR PUBLICATIONS

  • Ekstraksi, uji aktivitas antioksidan dan identifikasi golongan senyawa aktif alga merah Eucheuma spinosum dari perairan Banyuwangi
    U Mardiyah, AG Fasya, B Fauziyah, S Amalia
    Alchemy 3 (1), 39-46 2014
    Citations: 52

  • Uji Toksisitas Ekstrak Akuades (Suhu Kamar) Dan Akuades Panas (70 Oc) Daun Kelor (Moringa Oleifera Lamk.) Terhadap Larva Udang Artemia salina Leach
    S Anwar, E Yulianti, A Hakim, AG Fasya, B Fauziyah, R Muti'ah
    ALCHEMY: Journal of Chemistry, 84-92 2014
    Citations: 26

  • Ekstraksi, Uji Aktivitas Antioksidan Terhadap 1, 1-Difenil-2-Pikrilhidrazil (DPPH) dan Identifikasi Golongan Senyawa Aktif Alga Merah Eucheuma spinosum dari Perairan Banyuwangi
    U Mardiyah, AG Fasya, B Fauziyah, S Amalia
    Skripsi 2012
    Citations: 21

  • Analisis kadar logam tembaga (Cu) pada permen secara spektrofotometri serapan atom (AAS)
    E Rahmawati, DC Dewi, B Fauziyah
    Journal of Islamic Pharmacy 1 (1), 11-14 2015
    Citations: 19

  • Uji Antitoksoplasma Ekstrak Kasar Alkaloid Daun Pulai (Alstonia scholaris,(L.) R. BR) terhadap Mencit (Mus musculus) BALB/C yang Terinfeksi Toxoplasma Gondii Strain Rh
    A Abraham, AG Fasya, B Fauziyah, TK Adi
    ALCHEMY: Journal of Chemistry, 67-75 2014
    Citations: 14

  • Prediction of compounds from 96% Ethanol Extract of Marsilea crenata Presl. Leaves in increasing estrogen receptor-α activation
    B Ma'arif, FA Muslikh, DAP Fihuda, S Syarifuddin, B Fauziyah
     2021
    Citations: 10

  • Ensiklopedia Ilmu Farmasi: mengenal dunia pendidikan kefarmasian mulai dari ilmu dasar hingga terapan
    A Hakim, YYA Indrawijaya, R Mutiah, B Ma'arif, T Jati Dharma Dewi, ...
    UIN Maliki Press, Malang. Chrysanthemum cinerariifolium (Trev.) Vis dengan 2021
    Citations: 9

  • Bagasse nanocellulose (Saccharum officinarum L.): process optimization and characterization
    B Fauziyah, M Yuwono, I Isnaeni
    Annals of the Romanian Society for Cell Biology 25 (2), 989-1001 2021
    Citations: 9

  • Identifikasi golongan senyawa dan uji toksisitas akut ekstrak etanol 95% daun, kulit batang dan akar pulai (Alstonia scholaris (L.) R. Br.) terhadap mencit Balb/C
    F Ismiyah, B Fauziyah, AG Fasya, R Muti'ah
    ALCHEMY: Journal of Chemistry, 12-17 2014
    Citations: 9

  • Systematic Review: Anti-Osteoporosis Potential Activities Of Phytoestrogen Compounds In Chrysophyllum cainito L., Elaeis guineensis Jacq., Lannea acida Rich., Marsilea crenata
    B Ma'arif, S Suryanto, FA Muslikh, A Suryadinata, B Fauziyah
    Jurnal Farmasi Sains dan Komunitas (JFSK) 19 (1), 41-52 2022
    Citations: 8

  • Optimasi Parameter Analitik Biosensor Urea Berbasis Immobilisasi Urease dalam Membran Polianilin
    B Fauziyah
    Sainstis 2011
    Citations: 8

  • Studi in silico penghambatan aktivasi TLR2 ekstrak etanol daun semanggi (Marsilea crenata Presl.)
    B Ma'arif, DAP Fihuda, FA Muslikh, S Syarifuddin, B Fauziyah, DP Sari, ...
    Jurnal Tumbuhan Obat Indonesia 15 (1), 31-40 2022
    Citations: 7

  • The effect of acid variation on physical and chemical characteristics of cellulose isolated from Saccharum officinarum L. bagasse
    B Fauziyah, M Yuwono
    IOP Conference Series: Earth and Environmental Science 456 (1), 012016 2020
    Citations: 7

  • Development of an antimicrobial gel formulation for topical delivery using silver nanoparticle
    R Annisa, A Suryadinata, A Nashichuddin, R Mutiah, B Fauziyah
    Indian Journal of Novel Drug Delivery 11 (1), 13-19 2019
    Citations: 7

  • Effect of addition virgin coconut oil (VCO) on physical stability and SPF value of sunscreen cream combination of zinc oxide and titanium dioxide
    BC Jayati, R Annisa, AF Firdausy, DS Megawati, B Fauziyah
     2021
    Citations: 6

  • Tensile strength and elongation analysis on nano cellulose Film Isolated from Sugarcane Bagasse
    M Yuwono, B Fauziyah, A Nisak
    IOP Conference Series: Earth and Environmental Science 456 (1), 012088 2020
    Citations: 6

  • Pengaruh variasi konsentrasi propilen glikol sebagai Enhancer terhadap sediaan Transdermal Patch ibuprofen in Vitro
    M Misnamayanti
    Universitas Islam Negeri Maulana Malik Ibrahim 2019
    Citations: 6

  • Analysis of Metal Copper Concentration at Candy using Atomic Absorption Spectrophotometry (AAS)
    E Rahmawati, DC Dewi, AG Fasya, B Fauziyah
    ALCHEMY: Journal of Chemistry 4 (1), 39-43 2015
    Citations: 6

  • Optimasi metode penentuan kadar logam tembaga dan timbal dalam gula pasir secara spektrofotometri serapan atom dengan destruksi microwave digestion
    DC Dewi, B Fauziyah, A Suryadinata, D Annisa, N Afifah
    ALCHEMY: Journal of Chemistry 2013
    Citations: 6

  • Uji Toksisitas Ekstrak Kasar Alga Merah Eucheuma spinosum Pantai Lobuk Madura Terhadap Larva Udang Artemia salina Leach
    H Habibah
    Universitas Islam Negeri Maulana Malik Ibrahim 2012
    Citations: 6